Yan Xu

发表

Nanomechanical DNA origami 'single-molecule beacons' directly imaged by atomic force microscopy

M. Komiyama, A. Kuzuya, Y. Sakai, 2011, Nature communications.

Allosteric control of nanomechanical DNA origami pinching devices for enhanced target binding.

M. Komiyama, A. Kuzuya, Y. Sakai, 2017, Chemical communications.

Targeting human telomeric higher-order DNA: dimeric G-quadruplex units serve as preferred binding site.

Yan Xu, X. Qu, J. Ren, 2013, Journal of the American Chemical Society.

Clipping of Telomere from Human Chromosomes Using a Chemistry‐Based Artificial Restriction DNA Cutter

M. Komiyama, Yan Xu, Takumi Ishizuka, 2015, Current protocols in nucleic acid chemistry.

Linear consecutive hexaoxazoles as G4 ligands inducing chair-type anti-parallel topology of a telomeric G-quadruplex

T. Hirokawa, Yan Xu, Yue Ma, 2020, RSC advances.

Human telomere RNA and DNA form an intermolecular G-quadruplex.

M. Komiyama, Yan Xu, Takashi Kimura, 2008, Nucleic acids symposium series.

Consecutive formation of G-quadruplexes in human telomeric-overhang DNA: a protective capping structure for telomere ends.

M. Komiyama, Yan Xu, Takumi Ishizuka, 2009, Angewandte Chemie.

Human telomere RNA: a potential target for ligand recognition.

Yan Xu, 2012, Current pharmaceutical design.

Antiparallel RNA G-quadruplex Formed by Human Telomere RNA Containing 8-Bromoguanosine

Yan Xu, Takumi Ishizuka, Chao-Da Xiao, 2017, Scientific Reports.

Improving Thermodynamic Stability and Anticoagulant Activity of a Thrombin Binding Aptamer by Incorporation of 8-trifluoromethyl-2'-deoxyguanosine.

Yan Xu, Takumi Ishizuka, Y. Asada, 2020, Journal of medicinal chemistry.

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

David F. Boyd, D. Green, J. Crawford, 2020, Cell.

Human telomere RNA structure and function

Yan Xu, 2016 .

Photochemical approach to probing different DNA structures.

Yan Xu, H. Sugiyama, 2006, Angewandte Chemie.

Direct Light-up of cAMP Derivatives in Living Cells by Click Reactions

M. Komiyama, Yan Xu, Kenichiro Ito, 2013, Molecules.

A multi-functional guanine derivative for studying the DNA G-quadruplex structure.

Yan Xu, Takumi Ishizuka, Hong-Liang Bao, 2017, The Analyst.

19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures Using 19F-Labeled Nucleobase.

Yan Xu, Takumi Ishizuka, Hong-Liang Bao, 2019, Methods in molecular biology.

Recent progress in human telomere RNA structure and function.

Yan Xu, 2018, Bioorganic & medicinal chemistry letters.

Human telomeric DNA sequence-specific cleaving by G-quadruplex formation.

M. Komiyama, Yan Xu, Yuta Suzuki, 2009, Journal of the American Chemical Society.

Characterization of Structure and Catalytic Activity of a Complex between Heme and an All Parallel-Stranded Tetrameric G-Quadruplex Formed from DNA/RNA Chimera Sequence d(TTA)r(GGG)dT

Yan Xu, Takumi Ishizuka, Yasuhiko Yamamoto, 2020 .

A chiral wedge molecule inhibits telomerase activity.

Takashi Kawase, Hidetoshi Tahara, Hiroshi Sugiyama, 2010, Journal of the American Chemical Society.

(P)-helicene displays chiral selection in binding to Z-DNA.

Kazuhiko Tanaka, Hiroshi Sugiyama, Yan Xu, 2004, Journal of the American Chemical Society.

8-Methylguanosine: a powerful Z-DNA stabilizer.

Hiroshi Sugiyama, Yan Xu, H. Sugiyama, 2003, Journal of the American Chemical Society.

Click chemistry for the identification of G-quadruplex structures: discovery of a DNA-RNA G-quadruplex.

M. Komiyama, Yan Xu, Yuta Suzuki, 2009, Angewandte Chemie.

The new models of the human telomere d[AGGG(TTAGGG)3] in K+ solution.

Yan Xu, H. Sugiyama, Yu-taro Noguchi, 2006, Bioorganic & medicinal chemistry.

Telomeric repeat-containing RNA structure in living cells

M. Komiyama, Yan Xu, Yuta Suzuki, 2010, Proceedings of the National Academy of Sciences.

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.

Yan Xu, Yan Xu, 2011, Chemical Society reviews.

Structure Determination and Relative Properties of Novel Noncentrosymmetric Borates MM′4(BO3)3 (M: Na, M′: Ca and M: K, M′: Ca, Sr).

Yan Xu, Li Wu, Xia Chen, 2006 .

Characterization of human telomere RNA G-quadruplex structures in vitro and in living cells using 19F NMR spectroscopy

N. Kenmochi, T. Uechi, Yan Xu, 2017, Nucleic acids research.

Investigation of higher-order RNA G-quadruplex structures in vitro and in living cells by 19F NMR spectroscopy

Yan Xu, Hong-Liang Bao, Hongliang Bao, 2018, Nature Protocols.

Studying DNA G-Quadruplex Aptamer by 19F NMR

Atsushi Yamashita, Yan Xu, Takumi Ishizuka, 2017, ACS omega.

A U-tetrad stabilizes human telomeric RNA G-quadruplex structure.

M. Komiyama, Yan Xu, Takumi Ishizuka, 2010, Journal of the American Chemical Society.

The Conformational Study of Two Carbocyclic Nucleosides: Why Carbocyclic Nucleic Acids (CarNAs) Form More Stable Duplexes with RNA than DNA Does

Yan Xu, H. Sugiyama, K. Kino, 2002, Journal of biomolecular structure & dynamics.

2′-O-Methyl-8-methylguanosine as a Z-Form RNA Stabilizer for Structural and Functional Study of Z-RNA

Yan Xu, Takumi Ishizuka, Hong-Liang Bao, 2018, Molecules.

Structure of a human telomeric DNA sequence stabilized by 8‐bromoguanosine substitutions, as determined by NMR in a K+ solution

Yan Xu, H. Sugiyama, M. Katahira, 2007, The FEBS journal.

SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome

K. Zhao, Yan Xu, H. Sugiyama, 2012, Cell & Bioscience.

Helicase‐dependent isothermal DNA amplification

Yan Xu, H. Kong, Huimin Kong, 2004, EMBO reports.

Simultaneous amplification and screening of whole plasmids using the T7 bacteriophage replisome

Yan Xu, H. Kong, Huimin Kong, 2006, Nucleic acids research.

Hybrid-type and two-tetrad antiparallel telomere DNA G-quadruplex structures in living human cells

Yan Xu, Hong-Liang Bao, Hong-shan Liu, 2019, Nucleic acids research.

An intramolecular antiparallel G-quadruplex formed by human telomere RNA.

Yan Xu, Yasuhiko Yamamoto, Tomokazu Shibata, 2018, Chemical communications.

G-quadruplex formation by human telomeric repeats-containing RNA in Na+ solution.

M. Komiyama, Yan Xu, K. Kaminaga, 2008, Journal of the American Chemical Society.

Telomeric DNA-RNA-hybrid G-quadruplex exists in environmental conditions of HeLa cells.

Yan Xu, Hong-Liang Bao, Hongliang Bao, 2020, Chemical communications.

Finding a human telomere DNA-RNA hybrid G-quadruplex formed by human telomeric 6-mer RNA and 16-mer DNA using click chemistry: a protective structure for telomere end.

M. Komiyama, Yan Xu, Takumi Ishizuka, 2014, Bioorganic & medicinal chemistry.

Oligonucleotide Models of Telomeric DNA and RNA Form a Hybrid G-quadruplex Structure as a Potential Component of Telomeres*

M. Komiyama, Yan Xu, Takumi Ishizuka, 2012, The Journal of Biological Chemistry.

Structure-Dependent Binding of hnRNPA1 to Telomere RNA.

Yan Xu, Danzhou Yang, Takumi Ishizuka, 2017, Journal of the American Chemical Society.

A Small Ligand That Selectively Binds to the G-quadruplex at the Human Vascular Endothelial Growth Factor Internal Ribosomal Entry Site and Represses the Translation

Yan Xu, Shi-quan Gan, Chao-Da Xiao, 2021, Frontiers in Chemistry.

Antiparallel RNA G-quadruplex Formed by Human Telomere RNA Containing 8-Bromoguanosine

Yan Xu, Takumi Ishizuka, Chao-Da Xiao, 2017, Scientific Reports.

Unusual Topological RNA Architecture with an Eight-Stranded Helical Fragment Containing A-, G-, and U-Tetrads.

Yan Xu, H. Sugiyama, Takumi Ishizuka, 2017, Journal of the American Chemical Society.

Formation of the G-quadruplex and i-motif structures in retinoblastoma susceptibility genes (Rb)

Yan Xu, H. Sugiyama, 2006, Nucleic acids research.

G-rich sequence-specific recognition and scission of human genome by PNA/DNA hybrid G-quadruplex formation.

M. Komiyama, Yan Xu, Takumi Ishizuka, 2012, Angewandte Chemie.

Inhibition of translation by small RNA-stabilized mRNA structures in human cells.

M. Komiyama, Yan Xu, Kenichiro Ito, 2011, Journal of the American Chemical Society.

Human telomeric RNA r(UAGGGU) sequence forms parallel tetraplex structure with U-quartet.

M. Komiyama, Yan Xu, Takashi Kimura, 2009, Nucleic acids symposium series.

A 6-mer photocontrolled oligonucleotide as an effective telomerase inhibitor.

M. Komiyama, Yan Xu, Yuta Suzuki, 2010, Journal of the American Chemical Society.

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.

Yan Xu, Yan Xu, 2011, Chemical Society reviews.

Structure, function and targeting of human telomere RNA.

M. Komiyama, Yan Xu, 2012, Methods.

Click Chemistry Takes a Snapshot of DNA-RNA Hybrid G-Quadruplex in Living Cells

Yan Xu, Takumi Ishizuka, 2016 .

Photochemical determination of different DNA structures

Yan Xu, H. Sugiyama, Ryu Tashiro, 2007, Nature Protocols.

Highly efficient photochemical 2'-deoxyribonolactone formation at the diagonal loop of a 5-iodouracil-containing antiparallel G-quartet.

Yan Xu, H. Sugiyama, 2004, Journal of the American Chemical Society.

Efficient and erroneous incorporation of oxidized DNA precursors by human DNA polymerase eta.

Yan Xu, H. Sugiyama, F. Hanaoka, 2007, Biochemistry.

A nucleoside derivative 5-vinyluridine (VrU) for imaging RNA in cells and animals.

Yan Xu, Takumi Ishizuka, R. Nishii, 2019, Bioconjugate chemistry.

A chemistry-based method to detect individual telomere length at a single chromosome terminus.

M. Komiyama, Yan Xu, Takumi Ishizuka, 2013, Journal of the American Chemical Society.

Jason E. Rostron, A. Segall, Yan Xu, 2012, PloS one.

Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA.

M. Komiyama, Yan Xu, H. Sugiyama, 2013, Angewandte Chemie.

Efficient generation of 2'-deoxyuridin-5-yl at 5'-(G/C)AA(X)U(X)U-3' (X = Br, I) sequences in duplex DNA under UV irradiation.

Yan Xu, H. Sugiyama, T. Bando, 2005, Journal of the American Chemical Society.

Oligonucleotides DNA containing 8-trifluoromethyl-2′-deoxyguanosine for observing Z-DNA structure

Yan Xu, T. Oyoshi, Hong-Liang Bao, 2020, Nucleic acids research.

Conformation of G-quadruplex Controlled by Click Reaction

Yan Xu, Zhixing He, Chao-Da Xiao, 2020, Molecules.

Evidence for G‐Quadruplex DNA in Human Cells

M. Komiyama, Yan Xu, 2013, Chembiochem : a European journal of chemical biology.

Observation of Z‐DNA Structure via the Synthesis of Oligonucleotide DNA Containing 8‐Trifluoromethyl‐2‐Deoxyguanosine

Yan Xu, Hong-Liang Bao, Hongliang Bao, 2021, Current protocols.

Unveiling the role of G-quadruplex structure in promoter region: Regulation of ABCA1 expression in macrophages possibly via NONO protein recruitment.

Yan Xu, Chao-Da Xiao, Ling-yun Fu, 2023, International journal of biological macromolecules.

HnRNPA1 Specifically Recognizes the Base of Nucleotide at the Loop of RNA G-Quadruplex

Yan Xu, Xiao Liu, 2018, Molecules.

Stable lariat formation based on a G-quadruplex scaffold.

Hiroshi Sugiyama, Yan Xu, H. Sugiyama, 2008, Journal of the American Chemical Society.

Allosteric control of nanomechanical DNA origami pinching devices for enhanced target binding.

M. Komiyama, A. Kuzuya, Y. Sakai, 2017, Chemical communications.

I-motif and quadruplex-based device that can control a protein release or bind and release small molecule to influence biological processes.

Yan Xu, H. Sugiyama, Y. Nishimura, 2007, Bioorganic & medicinal chemistry.

Identification of a specific inhibitor of nOGA — a caspase-3 cleaved O-GlcNAcase variant during apoptosis

Yan Xu, Jing Li, Tiehai Li, 2012, Biochemistry (Moscow).

A multi-functional guanine derivative for studying the DNA G-quadruplex structure.

Yan Xu, Takumi Ishizuka, Hong-Liang Bao, 2017, The Analyst.

Conjugation of peptide nucleic acid with a pyrrole/imidazole polyamide to specifically recognize and cleave DNA.

M. Komiyama, Yan Xu, H. Sugiyama, 2013, Angewandte Chemie.

A chiral wedge molecule inhibits telomerase activity.

Yan Xu, H. Sugiyama, Takashi Kawase, 2010, Journal of the American Chemical Society.