C. Ambrose

发表

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Manish S. Shah, A. Poustka, D. Church, 1993, Cell.

Comparison of Soluble Decoy IgG Fusion Proteins of BAFF-R and BCMA as Antagonists for BAFF*

Yen-Ming Hsu, Fang Qian, Adrian Whitty, 2003, Journal of Biological Chemistry.

BAFF, a Novel Ligand of the Tumor Necrosis Factor Family, Stimulates B Cell Growth

J. Tschopp, P. Romero, K. Hofmann, 1999, The Journal of experimental medicine.

Baff Binds to the Tumor Necrosis Factor Receptor–Like Molecule B Cell Maturation Antigen and Is Important for Maintaining the Peripheral B Cell Population

J. Tschopp, C. Ambrose, M. Zafari, 2000, The Journal of experimental medicine.

A Soluble Form of B Cell Maturation Antigen, a Receptor for the Tumor Necrosis Factor Family Member April, Inhibits Tumor Cell Growth

J. Tschopp, C. Ambrose, P. Schneider, 2000, The Journal of experimental medicine.

Trinucleotide repeat length instability and age of onset in Huntington's disease

J. Penney, S. Folstein, A. Falek, 1993, Nature Genetics.

cellular depletion and survival blockade Anti-BR3 antibodies - a new class of B cell immunotherapy combining

D. Danilenko, D. Seshasayee, A. Ebens, 2008 .

Anti-BR3 antibodies: a new class of B-cell immunotherapy combining cellular depletion and survival blockade.

D. Danilenko, D. Seshasayee, A. Ebens, 2007, Blood.

Signaling Through the Lymphotoxin-β Receptor Stimulates HIV-1 Replication Alone and in Cooperation with Soluble or Membrane-Bound TNF-α

C. Ambrose, B. Brinkman, J. Browning, 1999, The Journal of Immunology.

Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies

C. Ambrose, J. Dayer, Y. Chicheportiche, 2001, Arthritis research.

Anti-CD19 CAR T Cells That Secrete a Biparatopic Anti-CLEC12A Bridging Protein Have Potent Activity Against Highly Aggressive Acute Myeloid Leukemia In Vitro and In Vivo

C. Ambrose, Lan Wu, Fay J. Dufort, 2021, Molecular Cancer Therapeutics.

Interaction affinity between cytokine receptor components on the cell surface.

A. Whitty, C. Ambrose, C. Benjamin, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Cutting Edge: BAFF Regulates CD21/35 and CD23 Expression Independent of Its B Cell Survival Function

M. Scott, C. Ambrose, S. Bixler, 2004, The Journal of Immunology.

Signaling through the lymphotoxin-beta receptor stimulates HIV-1 replication alone and in cooperation with soluble or membrane-bound TNF-alpha.

C. Ambrose, B. Brinkman, J. Browning, 1999, Journal of immunology.

An fMRI Investigation of Emotional Engagement in Moral Judgment

J. Tschopp, M. Scott, C. Ambrose, 2007 .

CAR-T Engager proteins optimize anti-CD19 CAR-T cell therapies for lymphoma

C. Ambrose, Lan Wu, P. Rennert, 2022, bioRxiv.

Dual role for TWEAK in angiogenic regulation.

C. Ambrose, T. Zheng, Jeffrey S. Thompson, 2002, Journal of cell science.

Antioxidant and Anti-inflammatory Activity of Eurycoma Longifolia Jack, A Traditional Medicinal Plant in Malaysia

C. Ambrose, T. Keisaban, 2013 .

The α-subunit of the skeletal muscle sodium channel is encoded proximal to Tk-1 on mouse Chromosome 11

J. Nadeau, M. MacDonald, J. Gusella, 2004, Mammalian Genome.

TWEAK induces liver progenitor cell proliferation.

C. Ambrose, T. Zheng, L. Burkly, 2005, The Journal of clinical investigation.

Characterization of lymphotoxin-alpha beta complexes on the surface of mouse lymphocytes.

C. Ambrose, C. Benjamin, P. Lawton, 1997, Journal of immunology.

A novel G protein-coupled receptor kinase gene cloned from 4p16.3.

D. Church, M. MacDonald, C. Ambrose, 1992, Human molecular genetics.

Follicular dendritic cell secreted protein FDC-SP controls IgA production

A. Miller, C. Ambrose, A. Marshall, 2014, Mucosal Immunology.

Mice Transgenic for Baff Develop Lymphocytic Disorders along with Autoimmune Manifestations

J. Tschopp, C. Ambrose, P. Schneider, 1999, The Journal of experimental medicine.

Anti-CD19 CAR T cells potently redirected to kill solid tumor cells

C. Ambrose, Lan Wu, Fay J. Dufort, 2020, bioRxiv.

De novo expansion of a (CAG)n repeat in sporadic Huntington's disease

J. Gusella, W. Koroshetz, J. Vonsattel, 1993, Nature genetics.

EC144 is a potent inhibitor of the heat shock protein 90.

S. Kasibhatla, I. Enyedy, C. Ambrose, 2012, Journal of medicinal chemistry.

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor

J. Haines, M. MacDonald, R. Martuza, 1993, Cell.

Interactions of Tumor Necrosis Factor (TNF) and TNF Receptor Family Members in the Mouse and Human*

J. Tschopp, C. Ambrose, P. Schneider, 2006, Journal of Biological Chemistry.

Identification of a Palmitic Acid-modified Form of Human Sonic hedgehog*

C. Ambrose, D. Baker, S. Bixler, 1998, The Journal of Biological Chemistry.

BAFF production by antigen-presenting cells provides T cell co-stimulation.

J. Tschopp, L. French, C. Ambrose, 2004, International immunology.

BAFF-R, a Newly Identified TNF Receptor That Specifically Interacts with BAFF

J. Tschopp, M. Scott, C. Ambrose, 2001, Science.

Molecular genetics of Huntington's disease.

J. Gusella, C. Ambrose, M. Duyao, 1993, Archives of neurology.

Preparation and Characterization of Soluble Recombinant Heterotrimeric Complexes of Human Lymphotoxins and (*)

C. Ambrose, J. Browning, D. Griffiths, 1996, The Journal of Biological Chemistry.

Normal and Expanded Huntington’s Disease Gene Alleles Produce Distinguishable Proteins Due to Translation Across the CAG Repeat

M. MacDonald, J. Gusella, J. Vonsattel, 1995, Molecular medicine.

The TNF family members BAFF and APRIL: the growing complexity.

C. Ambrose, F. Mackay, 2003, Cytokine & growth factor reviews.

Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF1

M. Scott, C. Putterman, C. Ambrose, 2006, The Journal of Immunology.

Deficient in BAFF Lupus-Prone New Zealand Mixed 2328 Mice Autoimmunity and Kidney Pathology in Paucity of Clinical Disease despite Serological

M. Scott, C. Putterman, C. Ambrose, 2006 .

BAFF overexpression and accelerated glomerular disease in mice with an incomplete genetic predisposition to systemic lupus erythematosus.

C. Putterman, C. Ambrose, F. Mackay, 2005, Arthritis and rheumatism.

BAFF supports human B cell differentiation in the lymphoid follicles through distinct receptors.

C. Ambrose, Y. Hsu, Y. Choi, 2005, International immunology.

BAFF selectively enhances the survival of plasmablasts generated from human memory B cells.

S. Tangye, P. Hodgkin, C. Ambrose, 2003, The Journal of clinical investigation.

BAFF: B cell survival factor and emerging therapeutic target for autoimmune disorders

C. Ambrose, S. Kalled, Y. Hsu, 2003, Expert opinion on therapeutic targets.

Cytotoxic activities of recombinant soluble murine lymphotoxin-alpha and lymphotoxin-alpha beta complexes.

C. Ambrose, M. Zafari, F. Mackay, 1997, Journal of immunology.

Synteny conservation of the Huntington's disease gene and surrounding loci on mouse Chromosome 5

J. Gusella, C. Ambrose, M. Duyao, 1994, Mammalian Genome.

Gametic but not somatic instability of CAG repeat length in Huntington's disease.

M. MacDonald, J. Penney, C. Ambrose, 1993, Journal of medical genetics.

The biochemistry and biology of BAFF, APRIL and their receptors.

C. Ambrose, S. Kalled, Y. Hsu, 2005, Current directions in autoimmunity.

Retargeting CD19 CAR T cells via engineered CD19-fusion proteins.

Justin R. Klesmith, C. Ambrose, Lan Wu, 2019, Molecular pharmaceutics.

A CD19-Anti-ErbB2 scFv Engager Protein Enables CD19-Specific CAR T Cells to Eradicate ErbB2+ Solid Cancer

C. Ambrose, H. Abken, P. Rennert, 2023, Cells.

Poly(Gp) Proteins Are A Useful Pharmacodynamic Marker For C9Orf72-Associated Amyotrophic Lateral Sclerosis

William T. Hu, Robert H. Brown, L. Petrucelli, 2017 .

Huntington's disease gene: Regional and cellular expression in brain of normal and affected individuals

M. MacDonald, J. Penney, A. Young, 1995, Annals of neurology.

Exon trapping and sequence-based methods of gene finding in transcript mapping of human 4p 16.3

D. Church, M. MacDonald, H. Lehrach, 1997, Somatic Cell Genetics.

Structure and expression of the Huntington's disease gene: Evidence against simple inactivation due to an expanded CAG repeat

R. Durbin, D. Church, M. MacDonald, 1994, Somatic cell and molecular genetics.

Mouse Huntington's disease gene homolog (Hdh)

M. MacDonald, J. Gusella, C. Ambrose, 1994, Somatic cell and molecular genetics.

Cloning of the α–adducin gene from the Huntington's disease candidate region of chromosome 4 by exon amplification

D. Church, D. Housman, R. Snell, 1992, Nature Genetics.

A Novel Role for Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure

Mohit M. Jain, C. Ambrose, C. Lim, 2009, Circulation.

Characterization of the G Protein-coupled Receptor Kinase GRK4

M. MacDonald, R. Stoffel, R. Lefkowitz, 1996, The Journal of Biological Chemistry.

Differential Expression of Normal and Mutant Huntington's Disease Gene Alleles

James F. Gusella, Marcy E. MacDonald, M. MacDonald, 1996, Neurobiology of Disease.

IT15 gene expression in fetal human brain

G. Bernhard Landwehrmeyer, James F. Gusella, Marcy E. MacDonald, 1994, Brain Research.

A gene from chromosome 4p16.3 with similarity to a superfamily of transporter proteins.

D. Church, M. MacDonald, D. Housman, 1993, Human molecular genetics.

Proinflammatory activity of TWEAK on human dermal fibroblasts and synoviocytes: blocking and enhancing effects of anti-TWEAK monoclonal antibodies

C. Ambrose, J. Dayer, Y. Chicheportiche, 2001, Arthritis research.

A Novel Role for Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) in the Development of Cardiac Dysfunction and Failure

Mohit M. Jain, C. Ambrose, C. Lim, 2009, Circulation.