A. Kling

发表

Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists.

H. Böhm, H. Riechers, H. Albrecht, 1996, Journal of medicinal chemistry.

Design and synthesis of 1,5- and 2,5-substituted tetrahydrobenzazepinones as novel potent and selective integrin α V β 3 antagonists

A. Kling, J. Delzer, Udo E W Lange, 2003 .

Highly potent and selective αVβ3-receptor antagonists: solid-phase synthesis and SAR of 1-substituted 4-amino-1H-pyrimidin-2-ones

A. Kling, J. Delzer, C. Zechel, 2003 .

Synthesis and SAR of N-substituted dibenzazepinone derivatives as novel potent and selective αVβ3 antagonists

A. Kling, J. Delzer, Udo E W Lange, 2002 .

Synthesis of highly potent and selective hetaryl ureas as integrin αVβ3-Receptor antagonists

A. Kling, J. Delzer, C. Zechel, 2002 .

Synthesis and SAR of highly potent dual 5-HT1A and 5-HT1B antagonists as potential antidepressant drugs.

M. Bakker, A. Kling, L. Unger, 2005, Bioorganic & medicinal chemistry letters.

Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.

A. Kling, M. Nijsen, V. Nimmrich, 2019, Bioorganic & medicinal chemistry letters.

Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.

A. Kling, M. Nijsen, A. Moeller, 2018, ACS medicinal chemistry letters.

Discovery of Novel and Highly Selective Inhibitors of Calpain for the Treatment of Alzheimer's Disease: 2-(3-Phenyl-1H-pyrazol-1-yl)-nicotinamides.

A. Kling, K. Marsh, C. Hutchins, 2017, Journal of medicinal chemistry.

Synthesis and SAR of highly potent and selective dopamine D3-receptor antagonists: 1H-Pyrimidin-2-one derivatives

A. Kling, L. Unger, W. Wernet, 2006 .

Facile Synthesis of a β(1‐3)‐Linked gal‐galactal Disaccharide and Its Use in N‐Iodosuccinimide‐Activated O‐Glycopeptide Synthesis

A. Kling, H. Kessler, M. Kottenhahn, 1990 .

Design and synthesis of novel potent and selective integrin αvβ3 antagonists—Novel synthetic routes to isoquinolinone, benzoxazinone, and quinazolinone acetates

Werner Seitz, A. Kling, Thomas Subkowski, 2008 .

Solution Structure of a Synthetic N-Glycosylated Cyclic Hexapeptide Determined by NMR Spectroscopy and MD Calculations

H. Matter, A. Kling, H. Kessler, 1991 .

Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.

Justin D Dietrich, A. Petros, V. Stoll, 2019, Journal of medicinal chemistry.

Discovery and synthesis of (S)-3-[2-(3,4-dimethoxyphenyl)ethoxy]-2- (4,6-dimethylpyrimidin-2-yloxy)-3,3-diphenylpropionic acid (LU 302872), a novel orally active mixed ET(A)/ET(B) receptor antagonist.

H. Riechers, W. Amberg, D. Klinge, 1999, Journal of medicinal chemistry.

Calpain inhibitor A-705253 mitigates Alzheimer's disease-like pathology and cognitive decline in aged 3xTgAD mice.

F. LaFerla, A. Kling, M. Kitazawa, 2012, The American journal of pathology.