P. Fernandes

发表

BMS-192548, a tetracyclic binding inhibitor of neuropeptide Y receptors, from Aspergillus niger WB2346. I. Taxonomy, fermentation, isolation and biological activity.

Y. Shu, K. Kodukula, M. Arcuri, 1995, The Journal of antibiotics.

In vitro and in vivo evaluation of tiacumicins B and C against Clostridium difficile

P. Fernandes, R. Swanson, D. Hardy, 1991, Antimicrobial Agents and Chemotherapy.

In vitro and in vivo activities of clarithromycin against Mycobacterium avium

P. Fernandes, R. Swanson, D. Hardy, 1989, Antimicrobial Agents and Chemotherapy.

Fluoroquinolone Antimicrobial Agents

P. Fernandes, A. Pernet, G. McHugh, 2022 .

Identification and structure-activity relationship studies of 3-methylene-2-norbornanone as potent anti-proliferative agents presumably working through p53 mediated apoptosis.

P. Fernandes, D. Stout, Jeanette R. Hill, 2004, Bioorganic & medicinal chemistry letters.

Comparative in vitro activities of new 14-, 15-, and 16-membered macrolides

P. Fernandes, C. Vojtko, D. Hardy, 1988, Antimicrobial Agents and Chemotherapy.

In vitro susceptibilities of mycoplasmas and ureaplasmas to new macrolides and aryl-fluoroquinolones

P. Fernandes, K. Waites, G. Cassell, 1988, Antimicrobial Agents and Chemotherapy.

In vitro evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones

R. Bailer, P. Fernandes, C. Vojtko, 1986, Antimicrobial Agents and Chemotherapy.

Morphology of Vibrio cholerae during enterotoxin production under anaerobic conditions.

P. Fernandes, J. M. Clark, H. L. Smith, 1977, Journal of ultrastructure research.

Pacidamycins, a novel series of antibiotics with anti-Pseudomonas aeruginosa activity. III. Microbiologic profile.

P. Fernandes, L. Coen, R. Swanson, 1989, The Journal of antibiotics.

Microbial resistance: Novel screens for a contemporary problem

P. Fernandes, Y. Tse‐Dinh, D. Hardy, 1999, Medicinal research reviews.

Coloradocin, an antibiotic from a new Actinoplanes. I. Taxonomy, fermentation and biological properties.

R. J. Theriault, P. Fernandes, J. Karwowski, 1987, The Journal of antibiotics.

Murine models for studying the pathogenesis and treatment of pyelonephritis.

R. R. Bower, P. Fernandes, N. Shipkowitz, 1987, Advances in experimental medicine and biology.

Membrane-bound Entero toxin of Vibrio cholerae

P. Fernandes, D. Bayer, 2008 .

Synthesis and antibacterial activity of novel 4-aryl-[1,2,3]-triazole containing macrolides.

P. Fernandes, David Pereira, D. Pereira, 2011, Bioorganic & medicinal chemistry letters.

Susceptibility of Campylobacter pylori to macrolides and fluoroquinolones.

P. Fernandes, D. Hardy, C. W. Hanson, 1988, The Journal of antimicrobial chemotherapy.

Phenelfamycins, a novel complex of elfamycin-type antibiotics. III. Activity in vitro and in a hamster colitis model.

P. Fernandes, L. Coen, R. Swanson, 1989, The Journal of antibiotics.

Aromatic dienoyl tetramic acids. Novel antibacterial agents with activity against anaerobes and staphylococci.

P. Fernandes, M. Marovich, T. Rosen, 1989, Journal of medicinal chemistry.

Synthesis and structure-activity relationship of 1-aryl-6,8-difluoroquinolone antibacterial agents.

P. Fernandes, R. Maleczka, A. Pernet, 1987, Journal of medicinal chemistry.

Synthesis and structure-activity relationships of new arylfluoronaphthyridine antibacterial agents.

P. Fernandes, A. Pernet, D. Chu, 1986, Journal of medicinal chemistry.

Chapter 14. Quinolone Antibacterial Agents

P. Fernandes, D. Chu, 1988 .

Synthesis and biological activity of benzothiazolo[3,2-a]quinolone antibacterial agents.

P. Fernandes, A. Pernet, D. Chu, 1986, Journal of medicinal chemistry.

Design, synthesis, and properties of (4S)-7-(4-amino-2-substituted-pyrrolidin-1-yl)quinolone-3-carboxylic acids.

P. Fernandes, K. Marsh, T. Rosen, 1988, Journal of medicinal chemistry.

Variability of clarithromycin and erythromycin susceptibility tests with Haemophilus influenzae in four different broth media and correlation with the standard disk diffusion test

P. Fernandes, J. Jorgensen, R. Jones, 1988, Journal of clinical microbiology.

Clerocidin, a terpenoid antibiotic, inhibits bacterial DNA gyrase.

J. S. Wells, P. Fernandes, M. Muller, 1993, The Journal of antibiotics.

Structure-activity relationships of the fluoroquinolones

P. Fernandes, C. Vojtko, D. Chu, 1989, Antimicrobial Agents and Chemotherapy.

Synthesis and structure-activity relationships of novel arylfluoroquinolone antibacterial agents.

P. Fernandes, R. Maleczka, A. Pernet, 1985, Journal of medicinal chemistry.

In-vitro and in-vivo potency of five new fluoroquinolones against anaerobic bacteria.

R. R. Bower, P. Fernandes, J. Weisz, 1986, The Journal of antimicrobial chemotherapy.

Structure-activity relationships in quinolone antibacterials: design, synthesis and biological activities of novel isothiazoloquinolones.

P. Fernandes, L. Shen, A. Pernet, 1988, Drugs under experimental and clinical research.

Asymmetric synthesis and properties of the enantiomers of the antibacterial agent 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-1,4-dihydro-6- fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid hydrochloride.

P. Fernandes, T. Rosen, S. Borodkin, 1988, Journal of medicinal chemistry.

Mode of Action, and In Vitro and In Vivo Activities of the Fluoroquinolones

P. Fernandes, 1988, Journal of clinical pharmacology.

Ascosteroside, a new antifungal agent from Ascotricha amphitricha. I. Taxonomy, fermentation and biological activities.

J. A. Gorman, D. Pirnik, P. Fernandes, 1996, The Journal of antibiotics.

A-61827 (A-60969), a new fluoronaphthyridine with activity against both aerobic and anaerobic bacteria

R. R. Bower, P. Fernandes, R. Swanson, 1988, Antimicrobial Agents and Chemotherapy.

Activity against Both Aerobic and Anaerobic Bacteria

R. R. Bower, P. Fernandes, R. Swanson, 2022 .

Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones

R. R. Bower, P. Fernandes, R. Swanson, 1987, Antimicrobial Agents and Chemotherapy.

In vitro and in vivo evaluation of A-56268 (TE-031), a new macrolide

R. R. Bower, R. Bailer, P. Fernandes, 1986, Antimicrobial Agents and Chemotherapy.

The effects of space flight on the production of monorden by Humicola fuscoatra WC5157 in solid-state fermentation

D. Klaus, P. Fernandes, S. Forenza, 1998, Applied Microbiology and Biotechnology.

Manumycins E, F and G, new members of manumycin class antibiotics, from Streptomyces sp.

J. S. Wells, Y. Shu, D. Pirnik, 1994, The Journal of antibiotics.

Characterization of membrane-bound nicotinamide adenine dinucleotide glycohydrolase of Vibrio cholerae.

P. Fernandes, M. Bayer, K. Welsh, 1979, The Journal of biological chemistry.

The frequency of in-vitro resistance development to fluoroquinolones and the use of a murine pyelonephritis model to demonstrate selection of resistance in vivo.

P. Fernandes, C. Vojtko, N. Shipkowitz, 1987, The Journal of antimicrobial chemotherapy.

Chapter 12 Quinolones

P. Fernandes, D. Chu, 1987 .

Susceptibility testing of macrolide antibiotics against Haemophilus influenzae and correlation of in vitro results with in vivo efficacy in a mouse septicemia model

R. Bailer, P. Fernandes, R. Swanson, 1987, Antimicrobial Agents and Chemotherapy.

Wall-less microbial isolate from a human renal biopsy

P. Fernandes, C. Panos, 1977, Journal of clinical microbiology.

10'-Desmethoxystreptonigrin, a novel analog of streptonigrin.

M. Barbacid, P. Fernandes, S. Huang, 1992, The Journal of antibiotics.

New macrolides active against Streptococcus pyogenes with inducible or constitutive type of macrolide-lincosamide-streptogramin B resistance

P. Fernandes, D. Hardy, E. McDonald, 1989, Antimicrobial Agents and Chemotherapy.

Membrane-bound enterotoxin of Vibrio cholerae.

P. Fernandes, M. Bayer, 1977, Journal of general microbiology.

The effect of anaerobiosis and bile salts on the growth and toxin production by Vibrio cholerae.

P. Fernandes, H. L. Smith, 1977, Journal of general microbiology.

Technological advances in high-throughput screening.

P. Fernandes, P. Fernandes, P B Fernandes, 1998, Current opinion in chemical biology.

Comparative in vitro potencies of nine new macrolides.

P. Fernandes, D. Hardy, 1988, Drugs under experimental and clinical research.

Effect of dosing intervals on efficacy of clarithromycin and erythromycin in mouse infection models.

P. Fernandes, R. Swanson, D. Hardy, 1988, Drugs under experimental and clinical research.

Synthesis and activity of nonhydrolyzable pseudomonic acid analogues.

P. Fernandes, L. L. Klein, P. Lartey, 1989, Journal of medicinal chemistry.

Synthesis and Activity on Nonhydrolyzable Pseudomonic Acid Analogues.

P. Fernandes, L. L. Klein, P. Lartey, 1989 .

In vivo evaluation of A-56619 (difloxacin) and A-56620: new aryl-fluoroquinolones

R. R. Bower, P. Fernandes, N. Shipkowitz, 1986, Antimicrobial Agents and Chemotherapy.

Correlation of in vitro activities of the fluoroquinolones to their in vivo efficacies.

P. Fernandes, R. Swanson, 1988, Drugs under experimental and clinical research.