Heping Cheng

Xianhua Wang, Heping Cheng, Tingting Hou, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Superoxide flashes: elemental events of mitochondrial ROS signaling in the heart.

Xianhua Wang, Heping Cheng, W. Shang, 2012, Journal of molecular and cellular cardiology.

CMYA5 establishes cardiac dyad architecture and positioning

W. Pu, Wenjun Xie, Heping Cheng, 2022, Nature Communications.

Ca 2 sparks and secretion in dorsal root ganglion neurons

Heping Cheng, Dongmei Yang, Xiao M Qin, 2005 .

Enhanced Gi Signaling Selectively Negates &bgr;2-Adrenergic Receptor (AR)– but Not &bgr;1-AR–Mediated Positive Inotropic Effect in Myocytes From Failing Rat Hearts

E. Lakatta, Heping Cheng, C. Balke, 2003, Circulation.

Spontaneous Activation of b 2-but Not b 1-Adrenoceptors Expressed in Cardiac Myocytes from b 1 b 2 Double Knockout Mice

E. Lakatta, Heping Cheng, Dongmei Yang, 2000 .

Spontaneous Activation of β2- but Not β1-Adrenoceptors Expressed in Cardiac Myocytes from β1β2 Double Knockout Mice

E. Lakatta, B. Kobilka, Heping Cheng, 2000 .

Arterial Labeling Ultrasound Subtraction Angiography (ALUSA) Based on Acoustic Phase-Change Nanodroplets.

Heping Cheng, Jue Zhang, Jiabin Zhang, 2022, Small.

Response to "A critical evaluation of cpYFP as a probe for superoxide".

Xianhua Wang, Heping Cheng, S. Sheu, 2011, Free radical biology & medicine.

Mitoflash biogenesis and its role in the autoregulation of mitochondrial proton electrochemical potential

Xianhua Wang, Heping Cheng, Jinghang Li, 2019, The Journal of general physiology.

Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy

Xianhua Wang, Heping Cheng, H. Takeshima, 2012, Science Translational Medicine.

Anomalous Subdiffusion of Calcium Spark in Cardiac Myocytes

Heping Cheng, Wenchang Tan, Kaitao Li, 2011 .

Structural and Mechanistic Bases of Nuclear Calcium Signaling in Human Pluripotent Stem Cell-Derived Ventricular Cardiomyocytes

Ronald A. Li, Heping Cheng, Wendy Keung, 2019, Stem cells international.

Mitofusin-2 Is a Major Determinant of Oxidative Stress-mediated Heart Muscle Cell Apoptosis*

Heping Cheng, Jian Tang, Wanrui Zhang, 2007, Journal of Biological Chemistry.

Linkage of beta1-adrenergic stimulation to apoptotic heart cell death through protein kinase A-independent activation of Ca2+/calmodulin kinase II.

B. Kobilka, Heping Cheng, Dongmei Yang, 2003, The Journal of clinical investigation.

Light-sheet fluorescence imaging charts the gastrula origin of vascular endothelial cells in early zebrafish embryos

Heping Cheng, Xiaojun Zhu, Liangyi Chen, 2020, bioRxiv.

Absence of physiological Ca2+ transients is an initial trigger for mitochondrial dysfunction in skeletal muscle following denervation

K. Dhakal, Heping Cheng, Jianjie Ma, 2017, Skeletal Muscle.

RyR 2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca 2 release ( SOICR )

Heping Cheng, Dongmei Yang, B. Xiao, 2004 .

RyR3 Amplifies RyR1-mediated Ca2+-induced Ca2+ Release in Neonatal Mammalian Skeletal Muscle*

Heping Cheng, Dongmei Yang, H. Takeshima, 2001, The Journal of Biological Chemistry.

Subtypes Optimizes -Adrenergic Modulation of Cardiac Contractility

E. Lakatta, Heping Cheng, Dongmei Yang, 2005 .

Effect in Myocytes From Failing Rat Hearts

E. Lakatta, Heping Cheng, C. Balke, 2003 .

Recent Advances in Cardiac b2-Adrenergic Signal Transduction

E. Lakatta, Heping Cheng, R. Xiao, 1999 .

Sustained beta1-adrenergic stimulation modulates cardiac contractility by Ca2+/calmodulin kinase signaling pathway.

M. Crow, Heping Cheng, Dongmei Yang, 2004, Circulation research.

Ser-2030, but not Ser-2808, is the major phosphorylation site in cardiac ryanodine receptors responding to protein kinase A activation upon beta-adrenergic stimulation in normal and failing hearts.

H. T. ter Keurs, M. Obayashi, Heping Cheng, 2006, The Biochemical journal.

Inhibition of Spontaneous β2-Adrenergic Activation Rescues β1-Adrenergic Contractile Response in Cardiomyocytes Overexpressing β2-Adrenoceptor*

E. Lakatta, R. Lefkowitz, W. Koch, 2000, The Journal of Biological Chemistry.

Paradoxical Cellular Ca 2 (cid:1) Signaling in Severe but Compensated Canine Left Ventricular Hypertrophy

S. Vatner, W. Lederer, Heping Cheng, 2005 .

Spontaneous Activation of b2- but Not b1-Adrenoceptors Expressed in Cardiac Myocytes from b1b2 Double Knockout Mice

E. Lakatta, Heping Cheng, Dongmei Yang, 2000 .

Carvedilol and its new analogs suppress arrhythmogenic store overload–induced Ca2+ release

H. Duff, A. Gillis, Heping Cheng, 2011, Nature Medicine.

Catecholaminergic-induced arrhythmias in failing cardiomyocytes associated with human HRCS96A variant overexpression.

Heping Cheng, Wen-Feng Cai, E. Kranias, 2011, American journal of physiology. Heart and circulatory physiology.

Programmed Cell Death 5 Provides Negative Feedback on Cardiac Hypertrophy Through the Stabilization of Sarco/Endoplasmic Reticulum Ca2+-ATPase 2a Protein

Heping Cheng, Yingyu Chen, Q. Zheng, 2018, Hypertension.

Coupling of (cid:98) 2 -Adrenoceptor to G i Proteins and Its Physiological Relevance in Murine Cardiac Myocytes

E. Lakatta, R. Lefkowitz, W. Koch, 1999 .

Erratum: Culture and adenoviral infection of adult mouse cardiac myocytes: Methods for cellular genetic physiology (American Journal of Physiology - Heart and Circulatory Physiology (July 2000) 279:48 (H429-H436))

E. Lakatta, B. Kobilka, Heping Cheng, 2000 .

Gi-Dependent Localization of β2-Adrenergic Receptor Signaling to L-Type Ca2+ Channels

E. Lakatta, H. Spurgeon, Heping Cheng, 2000 .

Ca(2+) signaling in cardiac myocytes overexpressing the alpha(1) subunit of L-type Ca(2+) channel.

E. Lakatta, Heping Cheng, Long-Sheng Song, 2002, Circulation Research.

Encoding of social novelty by sparse GABAergic neural ensembles in the prelimbic cortex

Y. Wu, Heping Cheng, Liangyi Chen, 2022, Science advances.

Hypersensitivity of BK Ca to Ca 2 (cid:1) Sparks Underlies Hyporeactivity of Arterial Smooth Muscle in Shock

Heping Cheng, Cai-hong Wu, Xiuqin Zhang, 2007 .

Spontaneous β2-Adrenergic Signaling Fails To Modulate L-Type Ca2+ Current in Mouse Ventricular Myocytes

Heping Cheng, Long-Sheng Song, E. Lakatta, 1999 .

Sinoatrial Node Pacemaker Activity Requires Ca 2 1 /Calmodulin-Dependent Protein Kinase II Activation Cellular Biology

Heping Cheng, Dongmei Yang, T. Vinogradova, 2000 .

Permeability Transition Pore-Mediated Mitochondrial Superoxide Flashes Mediate an Early Inhibitory Effect of Aβ1–42 on Neural Progenitor Cell Proliferation

Heping Cheng, A. Cheng, Ruiqian Wan, 2014 .

Local Control Models of Cardiac Excitation–Contraction Coupling

Michael D. Stern, Eduardo Ríos, Kenneth R. Boheler, 1999, The Journal of general physiology.

Heterodimerization of beta1- and beta2-adrenergic receptor subtypes optimizes beta-adrenergic modulation of cardiac contractility.

E. Lakatta, Heping Cheng, Dongmei Yang, 2005, Circulation research.

Direct measurement of SR release flux by tracking ‘Ca2+ spikes’ in rat cardiac myocytes

E. Lakatta, Heping Cheng, M. Stern, 1998, The Journal of physiology.

Identification of EFHD1 as a novel Ca(2+) sensor for mitoflash activation.

Liping Wei, Xianhua Wang, Heping Cheng, 2016, Cell calcium.

Imaging ROS signaling in cells and animals

Xianhua Wang, Heping Cheng, W. Shang, 2013, Journal of Molecular Medicine.

Ca 2 (cid:1) /Calmodulin Kinase II–Dependent Phosphorylation of Ryanodine Receptors Suppresses Ca 2 (cid:1) Sparks and Ca 2 (cid:1) Waves in Cardiac Myocytes

E. Lakatta, Didier X. P. Brochet, Heping Cheng, 2007 .

Cardiovascular research as a forum for publications from China: present, past, and future.

Heping Cheng, K. Sipido, Diane Gal, 2014, Cardiovascular research.

Cheng et al. reply

M. Dong, Xianhua Wang, Heping Cheng, 2014, Nature.

High Basal Protein Kinase A–Dependent Phosphorylation Drives Rhythmic Internal Ca2+ Store Oscillations and Spontaneous Beating of Cardiac Pacemaker Cells

E. Lakatta, Heping Cheng, Dongmei Yang, 2006, Circulation research.

Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes.

Heping Cheng, Dongmei Yang, Xiaomei Lan, 2008, Cell calcium.

Sustained &bgr;1-Adrenergic Stimulation Modulates Cardiac Contractility by Ca2+/Calmodulin Kinase Signaling Pathway

M. Crow, Heping Cheng, Dongmei Yang, 2004 .

Subtype-specific β-adrenoceptor signaling pathways in the heart and their potential clinical implications

Heping Cheng, E. Lakatta, Heping Cheng, 2004 .

Sustained (cid:1) 1 -Adrenergic Stimulation Modulates Cardiac Contractility by Ca 2 (cid:2) /Calmodulin Kinase Signaling Pathway Cellular Biology

M. Crow, Heping Cheng, Dongmei Yang, 2004 .

Imaging Ca2+ Nanosparks in Heart With a New Targeted Biosensor

M. Cannell, Xianhua Wang, Heping Cheng, 2014, Circulation research.

A Method to Measure Myocardial Calcium Handling in Adult Drosophila

N. Bursac, Heping Cheng, H. Rockman, 2011, Circulation research.

Sparks and Puffs in Oligodendrocyte Progenitors: Cross Talk between Ryanodine Receptors and Inositol Trisphosphate Receptors

Heping Cheng, Long-Sheng Song, T. Molinski, 2001, The Journal of Neuroscience.

FeCeOx with improved activity for catalytic reduction of NO with NH3

Heping Cheng, Zhen Ma, Junbo Wang, 2020 .

ROS regulation of microdomain Ca(2+) signalling at the dyads.

Xianhua Wang, Heping Cheng, Huiliang Zhang, 2013, Cardiovascular research.

Imaging superoxide flash and metabolism-coupled mitochondrial permeability transition in living animals

Feng Gao, Jianjie Ma, Xing Zhang, 2011, Cell Research.

The mechanosensitive Piezo1 channel mediates heart mechano-chemo transduction

Heping Cheng, B. Xiao, Shi-Qiang Wang, 2021, Nature Communications.

Synergistic Triggering of Superoxide Flashes by Mitochondrial Ca2+ Uniport and Basal Reactive Oxygen Species Elevation*

Feng Gao, Xing Zhang, Heping Cheng, 2013, The Journal of Biological Chemistry.

Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes*

Xianhua Wang, Heping Cheng, Quan Chen, 2012, The Journal of Biological Chemistry.

Cyclophilin D regulates mitochondrial flashes and metabolism in cardiac myocytes.

Huaqiang Fang, Heping Cheng, Xianhua Wang, 2016, Journal of molecular and cellular cardiology.

Mitochondrial superoxide flashes - From signaling to disease

Xianhua Wang, Heping Cheng, Wang Wang, 2014 .

Bidirectional regulation of Ca2+ sparks by mitochondria-derived reactive oxygen species in cardiac myocytes.

Wenjun Xie, Heping Cheng, Jie Liu, 2008, Cardiovascular research.

Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle

Xianhua Wang, Heping Cheng, W. Shang, 2015, Journal of Molecular Medicine.

Cardioprotection of Ischemia/Reperfusion Injury by Cholesterol-Dependent MG53-Mediated Membrane Repair

Wenjun Xie, Xianhua Wang, Heping Cheng, 2010, Circulation research.

STIM1- and Orai1-mediated Ca2+ oscillation orchestrates invadopodium formation and melanoma invasion

Heping Cheng, Wei-Chiao Chang, A. Sarnaik, 2014, The Journal of cell biology.

Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans

Yu Shyr, Pei-Fang Su, Meng-Qiu Dong, 2014, Nature.

Imaging Microglia Surveillance during Sleep-wake Cycles in Freely Behaving Mice

Xianhua Wang, Heping Cheng, Huaqiang Fang, 2023, bioRxiv.

NDUFAB1 confers cardio-protection by enhancing mitochondrial bioenergetics through coordination of respiratory complex and supercomplex assembly

Xinli Hu, Xianhua Wang, Heping Cheng, 2019, Cell Research.

Exogenous nucleic acids aggregate in non-P-body cytoplasmic granules when transfected into cultured cells

Wenjun Xie, Heping Cheng, Zicai Liang, 2010, Frontiers in Biology.

Calcium flickers steer cell migration

Heping Cheng, Xianhua Wang, Long-Sheng Song, 2009, Nature.

DB130035 3736..3746

Heping Cheng, N. Hou, Jue Wang, 2013 .

Overnutrition Stimulates Intestinal Epithelium Proliferation Through β-Catenin Signaling in Obese Mice

Heping Cheng, N. Hou, Xiaomin Hu, 2013, Diabetes.

Mitochondrial Superoxide Production Negatively Regulates Neural Progenitor Proliferation and Cerebral Cortical Development

Mark P Mattson, Heping Cheng, Aiwu Cheng, 2012, Stem cells.

1B50-1, a mAb raised against recurrent tumor cells, targets liver tumor-initiating cells by binding to the calcium channel α2δ1 subunit.

Wei Zhao, Heping Cheng, B. Xing, 2013, Cancer cell.

Hypersensitivity of BKCa to Ca2+ Sparks Underlies Hyporeactivity of Arterial Smooth Muscle in Shock

Heping Cheng, N. Hou, Cai-hong Wu, 2007, Circulation research.

Uncontrolled calcium sparks act as a dystrophic signal for mammalian skeletal muscle

Jianjie Ma, Heping Cheng, Marco Brotto, 2005, Nature Cell Biology.

Adaptive mechanisms of intracellular calcium homeostasis in mammalian hibernators.

E. Lakatta, Heping Cheng, Shi-Qiang Wang, 2002, The Journal of experimental biology.

Rad As a Novel Regulator of Excitation–Contraction Coupling and &bgr;-Adrenergic Signaling in Heart

Wenjun Xie, Heping Cheng, Xiaojun Zhu, 2010, Circulation research.

Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds

Heping Cheng, Caiye Zhu, Youji Ma, 2021, Biology open.

Dysfunction of store-operated calcium channel in muscle cells lacking mg29

Heping Cheng, Dongmei Yang, M. Nishi, 2002, Nature Cell Biology.

Methylation-associated silencing of MicroRNA-335 contributes tumor cell invasion and migration by interacting with RASA1 in gastric cancer.

Heping Cheng, Ke Yang, Z. Jie, 2014, American journal of cancer research.

Calcium sparks.

Heping Cheng, W. Lederer, Heping Cheng, 2008, Physiological reviews.

The third intracellular loop and the carboxyl terminus of beta2-adrenergic receptor confer spontaneous activity of the receptor.

B. Kobilka, Heping Cheng, Dongmei Yang, 2003, Molecular pharmacology.

A running title: Intestinal GSK3β/βcatenin signaling in obesity

Heping Cheng, N. Hou, Xiaomin Hu, 2013 .

Prostaglandin A2-mediated Stabilization of p21 mRNA through an ERK-dependent Pathway Requiring the RNA-binding Protein HuR*

M. Gorospe, Jinshui Fan, Xiaoling Yang, 2004, Journal of Biological Chemistry.

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

L. Saksida, T. Bussey, Heping Cheng, 2019, bioRxiv.

Rapid volumetric imaging with Bessel-Beam three-photon microscopy.

Zhe Zhao, Guoqing Chen, Haitao Wu, 2018, Biomedical optics express.

The quantal nature of Ca2+ sparks and in situ operation of the ryanodine receptor array in cardiac cells.

Eduardo Ríos, Heping Cheng, Michael D Stern, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Cellular Mechanisms of p 38 MAPK – Induced Negative Inotropic Effect : Suppression of Myofilament Ca

Heping Cheng, Yibin Wang, M. Zheng, 2002 .

Mitochondrial flashes: new insights into mitochondrial ROS signalling and beyond

Heping Cheng, Xianhua Wang, Xianhua Wang, 2014, The Journal of physiology.

Superoxide flashes reveal novel properties of mitochondrial reactive oxygen species excitability in cardiomyocytes.

Wenjun Xie, Xianhua Wang, Heping Cheng, 2012, Biophysical journal.

Ca2+ sparks and secretion in dorsal root ganglion neurons.

Heping Cheng, Dongmei Yang, Xiao M Qin, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Rhesus Macaques Develop Metabolic Syndrome With Reversible Vascular Dysfunction Responsive to Pioglitazone

Heping Cheng, Paul L. Huang, N. Hou, 2011, Circulation.

Orphaned ryanodine receptors in the failing heart.

Eric A Sobie, Heping Cheng, Long-Sheng Song, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Imaging elemental events of store-operated Ca2+ entry in invading cancer cells with plasmalemmal targeted sensors

Xianhua Wang, Heping Cheng, Jinghang Li, 2019, Journal of Cell Science.

Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure

Chuan-Yun Li, Xianhua Wang, Heping Cheng, 2020, Cell Death & Disease.

Na/Ca exchanger: Molecular and cellular characteristics

R. Kieval, P. Lipp, W. Lederer, 1996 .

Frequency-encoding Thr17 Phospholamban Phosphorylation Is Independent of Ser16 Phosphorylation in Cardiac Myocytes*

Heping Cheng, R. Xiao, Weizhong Zhu, 2000, The Journal of Biological Chemistry.

Imaging microdomain Ca2+ in muscle cells.

Heping Cheng, Long-Sheng Song, Didier X. P. Brochet, 2004, Circulation research.

Visualizing Seizure Propagation in Freely-moving Mice via Miniature Two-photon Microscopy

Heping Cheng, Wei-Na Jin, Qiang Liu, 2022, Neuroscience Bulletin.

Isobaric Tags for Relative and Absolute Quantification-Based Proteomics Reveals Candidate Proteins of Fat Deposition in Chinese Indigenous Sheep With Morphologically Different Tails

Heping Cheng, Caiye Zhu, Youji Ma, 2021, Frontiers in Genetics.

Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging

Heping Cheng, Haitao Wu, Liangyi Chen, 2021, Nature Methods.

Miniature Fluorescence Microscopy for Imaging Brain Activity in Freely-Behaving Animals

Dong Zhang, Heping Cheng, Shiyuan Chen, 2020, Neuroscience Bulletin.

Mitochondrial Flash: Integrative Reactive Oxygen Species and pH Signals in Cell and Organelle Biology

Xianhua Wang, Heping Cheng, S. Sheu, 2016, Antioxidants & redox signaling.

Gi Protein-mediated Functional Compartmentalization of Cardiac β2-Adrenergic Signaling*

E. Lakatta, Heping Cheng, Ye Chen, 1999, The Journal of Biological Chemistry.

Prohibitin 2 deficiency impairs cardiac fatty acid oxidation and causes heart failure

Chuan-Yun Li, Xianhua Wang, Heping Cheng, 2020, Cell Death & Disease.

Β-adrenergic-stimulated L-type channel Ca²+ entry mediates hypoxic Ca²+ overload in intact heart.

Xianhua Wang, Heping Cheng, Guangju Ji, 2013, Journal of molecular and cellular cardiology.

RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR).

Heping Cheng, Dongmei Yang, B. Xiao, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Functional Consequence of Protein Kinase A-dependent Phosphorylation of the Cardiac Ryanodine Receptor

Wenjun Xie, Xianhua Wang, Heping Cheng, 2007, Journal of Biological Chemistry.

Respective Contribution of Mitochondrial Superoxide and pH to Mitochondria-targeted Circularly Permuted Yellow Fluorescent Protein (mt-cpYFP) Flash Activity*

David I. Yule, Heping Cheng, Xianhua Wang, 2013, The Journal of Biological Chemistry.

Brain activity regulates loose coupling between mitochondrial and cytosolic Ca2+ transients

W. Gan, Avital Adler, Xianhua Wang, 2019, Nature Communications.

Ca(2+)-induced Ca(2+) release in sensory neurons: low gain amplification confers intrinsic stability.

Heping Cheng, Cai-hong Wu, K. Ouyang, 2005, The Journal of biological chemistry.

Calmodulin Regulation of Excitation-Contraction Coupling in Cardiac Myocytes

Heping Cheng, Dongmei Yang, Long-Sheng Song, 2003, Circulation research.

Kissing and nanotunneling mediate intermitochondrial communication in the heart

Clara Franzini-Armstrong, Heping Cheng, Xianhua Wang, 2013, Proceedings of the National Academy of Sciences.

Mitochondrial flashes: From indicator characterization to in vivo imaging.

Heping Cheng, Huiliang Zhang, Wang Wang, 2016, Methods.

Superoxide flashes: illuminating new insights into cardiac ischemia/reperfusion injury.

Heping Cheng, S. Sheu, Wang Wang, 2008, Future cardiology.

Dynamics of a disinhibitory prefrontal microcircuit in controlling social competition

Hailan Hu, Heping Cheng, Huan Ma, 2021, Neuron.

Remodeling of Mitochondrial Flashes in Muscular Development and Dystrophy in Zebrafish

Xiaojun Zhu, Yingchun Hu, Jing-Wei Xiong, 2015, PloS one.

Permeability transition pore-mediated mitochondrial superoxide flashes mediate an early inhibitory effect of amyloid beta1−42 on neural progenitor cell proliferation

M. Mattson, Heping Cheng, A. Cheng, 2014, Neurobiology of Aging.

NDUFAB1 Protects Heart by Coordinating Mitochondrial Respiratory Complex and Supercomplex Assembly

Xinli Hu, Xianhua Wang, Heping Cheng, 2018, bioRxiv.

Fluorescence-Based Measurements of Store-Operated Ca2+ Entry in Cancer Cells Using Fluo-4 and Confocal Live-Cell Imaging.

Heping Cheng, Tao Sun, Shengyu Yang, 2018, Methods in molecular biology.

Spatiotemporal regulation of store-operated calcium entry in cancer metastasis.

Heping Cheng, Shengyu Yang, Yunzhan Li, 2021, Biochemical Society transactions.

Mitochondrial PIP3-binding protein FUNDC2 supports platelet survival via AKT signaling pathway

Heping Cheng, Rong Zhang, Quan Chen, 2018, Cell Death & Differentiation.

Hydrogen peroxide primes heart regeneration with a derepression mechanism

Chuan-Yun Li, Heping Cheng, Chuanmao Zhang, 2014, Cell Research.

Ca2+ blinks: rapid nanoscopic store calcium signaling.

Clara Franzini-Armstrong, Heping Cheng, W. Lederer, 2005, Proceedings of the National Academy of Sciences of the United States of America.

Use of Chimeric Fluorescent Proteins and Fluorescence Resonance Energy Transfer to Monitor Cellular Responses Imaging Microdomain Ca in Muscle Cells Optical Imaging of the Heart Examining Intracellular Organelle Function Using Fluorescent Probes Two-Photon Microscopy of Cells and Tissues

Didier X. P. Brochet, Heping Cheng, Dongmei Yang, 2004 .

Functional network topography of the medial entorhinal cortex

T. Bonhoeffer, M. Moser, E. Moser, 2021, Proceedings of the National Academy of Sciences.

Miniature three-photon microscopy maximized for scattered fluorescence collection

Fei Yu, Heping Cheng, Liangyi Chen, 2023, Nature Methods.

Miniature two-photon microscopy for enlarged field-of-view, multi-plane and long-term brain imaging

Heping Cheng, Liangyi Chen, Runlong Wu, 2021, Nature Methods.

Blinking Acoustic Nanodroplets Enable Fast Super-resolution Ultrasound Imaging.

Heping Cheng, Jue Zhang, Jiabin Zhang, 2021, ACS nano.

Thermodynamically irreversible gating of ryanodine receptors in situ revealed by stereotyped duration of release in Ca(2+) sparks.

E. Lakatta, Heping Cheng, M. Stern, 2002, Biophysical journal.

Calcium Sparks: Release Packets of Uncertain Origin and Fundamental Role

Heping Cheng, M. Stern, E. Ríos, 1999, The Journal of general physiology.

Central role of IP3R2-mediated Ca2+ oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor

Xianhua Wang, Heping Cheng, Wei Zhao, 2019, Cell Death & Disease.

New imaging instrument in animal models: Two‐photon miniature microscope and large field of view miniature microscope for freely behaving animals

Heping Cheng, Changliang Guo, Liangyi Chen, 2022, Journal of neurochemistry.

Ca2+-induced Ca2+ Release in Sensory Neurons

Heping Cheng, Cai-hong Wu, K. Ouyang, 2005, Journal of Biological Chemistry.

T-Tubule Remodeling During Transition From Hypertrophy to Heart Failure

Sheng Wei, Heping Cheng, Long-Sheng Song, 2010, Circulation research.

Cardioprotection by CaMKII-&dgr;B Is Mediated by Phosphorylation of Heat Shock Factor 1 and Subsequent Expression of Inducible Heat Shock Protein 70

Heping Cheng, Wei Peng, Heping Cheng, 2010, Circulation research.

Expression Of aquaporin-1 (AQP-1) in rat heart

E. Lakatta, M. Crow, W. Lederer, 1999 .

Long-term, in toto live imaging of cardiomyocyte behaviour during mouse ventricle chamber formation at single-cell resolution

Aibin He, Heping Cheng, Bin Zhou, 2020, Nature Cell Biology.

BacFlash signals acid-resistance gene expression in bacteria

Xianhua Wang, Heping Cheng, Tao Sun, 2020, Cell Research.

Temperature dependence of mitoflash biogenesis in cardiac mitochondria.

Xianhua Wang, Heping Cheng, Jinghang Li, 2019, Archives of biochemistry and biophysics.

Mitochondrial flashes regulate ATP homeostasis in the heart

Feng Gao, Jinghang Li, Heping Cheng, 2017, eLife.

Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity

Pak-Ming Lau, Guo-Qiang Bi, Huaqiang Fang, 2017, Nature Communications.

Mitochondrial Flashes: Elemental Signaling Events in Eukaryotic Cells.

Heping Cheng, Xianhua Wang, Xianhua Wang, 2017, Handbook of experimental pharmacology.

Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics

Xianhua Wang, Heping Cheng, Tao Sun, 2016, Scientific Reports.

Protons Trigger Mitochondrial Flashes.

Feng Gao, Heping Cheng, Xianhua Wang, 2016, Biophysical journal.

Mitoflash altered by metabolic stress in insulin-resistant skeletal muscle

Xianhua Wang, Heping Cheng, W. Shang, 2015, Journal of Molecular Medicine.

Large-field high-resolution two-photon digital scanned light-sheet microscopy

Liangyi Chen, Weijian Zong, Huixia Ren, 2014, Cell Research.

Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations

Xianhua Wang, Heping Cheng, Chongshu Jian, 2014, Science China Life Sciences.

Superoxide constitutes a major signal of mitochondrial superoxide flash.

Feng Gao, Xing Zhang, Heping Cheng, 2013, Life sciences.

Superoxide Flashes

Xianhua Wang, Heping Cheng, Quan Chen, 2011, The Journal of Biological Chemistry.

Adiponectin regulates SR Ca(2+) cycling following ischemia/reperfusion via sphingosine 1-phosphate-CaMKII signaling in mice.

F. Gao, W. Koch, Heping Cheng, 2014, Journal of molecular and cellular cardiology.

Activation of CaMKIIδC Is a Common Intermediate of Diverse Death Stimuli-induced Heart Muscle Cell Apoptosis*

M. Crow, Heping Cheng, Dongmei Yang, 2007, Journal of Biological Chemistry.

An optimized acetylcholine sensor for monitoring in vivo cholinergic activity

L. Saksida, T. Bussey, Heping Cheng, 2020, Nature Methods.

Paradoxical Cellular Ca2+ Signaling in Severe but Compensated Canine Left Ventricular Hypertrophy

S. Vatner, W. Lederer, Heping Cheng, 2005, Circulation research.

Calcium dysregulation mediates mitochondrial and neurite outgrowth abnormalities in SOD2 deficient embryonic cerebral cortical neurons

M. Mattson, Heping Cheng, A. Cheng, 2018, Cell Death & Differentiation.

Ca2+/Calmodulin Kinase II–Dependent Phosphorylation of Ryanodine Receptors Suppresses Ca2+ Sparks and Ca2+ Waves in Cardiac Myocytes

E. Lakatta, Didier X. P. Brochet, Heping Cheng, 2007, Circulation research.

Regulation of superoxide flashes by transient and steady mitochondrial calcium elevations

Xianhua Wang, Heping Cheng, Chongshu Jian, 2014, Science China Life Sciences.

Flash Sniper: Automated Detection and Analysis of Mitochondrial Superoxide Flash

Jie Liu, Wang Wang, Wenchang Tan, 2009 .

Dendritic mitoflash as a putative signal for stabilizing long-term synaptic plasticity

G. Bi, Pak-Ming Lau, Xianhua Wang, 2017, Nature Communications.

Cardiac-specific Overexpression of the α1 Subunit of the L-type Voltage-dependent Ca2+ Channel in Transgenic Mice

E. Lakatta, H. Yamaguchi, I. Grupp, 1999, The Journal of Biological Chemistry.

Nitroxyl Improves Cellular Heart Function by Directly Enhancing Cardiac Sarcoplasmic Reticulum Ca2+ Cycling

M. Zaccolo, D. Kass, G. M. Wilson, 2007, Circulation research.

β-Adrenergic signaling accelerates and synchronizes cardiac ryanodine receptor response to a single L-type Ca2+ channel

Shu-Hua Bai, Heping Cheng, Edward G Lakatta, 2009, Proceedings of the National Academy of Sciences.

Putting out the fire: what terminates calcium-induced calcium release in cardiac muscle?

Heping Cheng, Michael D Stern, Heping Cheng, 2004, Cell calcium.

An anomalous subdiffusion model for calcium spark in cardiac myocytes

Wenchang Tan, Heping Cheng, Ceji Fu, 2007 .

Central role of IP3R2-mediated Ca2+ oscillation in self-renewal of liver cancer stem cells elucidated by high-signal ER sensor

Xianhua Wang, Heping Cheng, Wei Zhao, 2019, Cell Death & Disease.

Calcium signaling between sarcolemmal calcium channels and ryanodine receptors in heart cells.

Heping Cheng, Shi-Qiang Wang, 2002, Frontiers in bioscience : a journal and virtual library.

Elementary calcium release events from the sarcoplasmic reticulum in the heart.

W. Lederer, Didier X. P. Brochet, Heping Cheng, 2012, Advances in experimental medicine and biology.

Systemic ablation of RyR3 alters Ca2+ spark signaling in adult skeletal muscle.

Heping Cheng, H. Takeshima, Jianjie Ma, 2007, Cell calcium.

Two-photon three-axis digital scanned light-sheet microscopy (2P3A-DSLM)

Zhuan Zhou, Weijian Zong, Jia Zhao, 2014, 2014 Conference on Lasers and Electro-Optics (CLEO) - Laser Science to Photonic Applications.

Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle.

W. Lederer, M. Cannell, H. Cheng, 1993, Science.

Ca2+ Signaling in Cardiac Myocytes Overexpressing the &agr;1 Subunit of L-Type Ca2+ Channel

E. Lakatta, Heping Cheng, Long-Sheng Song, 2002 .

Non-Invasive Skin Imaging Assessment of Human Stress During Head-Down Bed Rest Using a Portable Handheld Two-Photon Microscope

Heping Cheng, Yan Ren, Qiang Fu, 2022, Frontiers in Physiology.

Calcium sparks and [Ca2+]i waves in cardiac myocytes.

W. Lederer, M. Cannell, H. Cheng, 1996, The American journal of physiology.

p38 Mitogen-Activated Protein Kinase Mediates a Negative Inotropic Effect in Cardiac Myocytes

Heping Cheng, Yibin Wang, M. Zheng, 2002, Circulation research.

Subunit of L-Type Ca Channel