J. Laramie

发表

Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants

D. Altshuler, L. Groop, B. Voight, 2011, Genetic epidemiology.

Multiple Genes Influence BMI on Chromosome 7q31–34: The NHLBI Family Heart Study

Ingrid B. Borecki, Michael A. Province, Jason M. Laramie, 2009, Obesity.

A Bayesian mathematical model of motor and cognitive outcomes in Parkinson’s disease

A. Singleton, B. Hayete, C. Tanner, 2017, PloS one.

NYD-SP18 is associated with obesity in the NHLBI Family Heart Study

I. Borecki, M. Province, J. Wilk, 2008, International Journal of Obesity.

The Framingham Heart Study 100K SNP genome-wide association study resource: overview of 17 phenotype working group reports

Sudha Seshadri, Qiong Yang, Chao-Yu Guo, 2007, BMC Medical Genetics.

Functional genomics of critical illness and injury

M. Province, J. Cobb, J. Laramie, 2002, Critical care medicine.

Physiologic genomics.

J. Cobb, J. McDunn, J. Laramie, 2006, Surgery.

Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program

E. Boerwinkle, A. Chakravarti, S. Hunt, 2006, BMC Medical Genetics.

Program Tompkins and the Inflammation and Host Response to Injury , Large-Scale Collaborative

D. Schoenfeld, R. Tompkins, W. Xiao, 2004 .

The Gly2019Ser mutation in LRRK2 is not fully penetrant in familial Parkinson's disease: the GenePD study

H. Shill, J. Growdon, S. Sherman, 2008, BMC medicine.

Coronary Artery Disease Polygenic Risk Score Identifies Patients at Higher Risk for Recurrent Cardiovascular Events in the CANTOS Trial.

Aviv Madar, P. Ridker, J. Laramie, 2021, Circulation. Genomic and precision medicine.

Late Breaking Abstract - The biological pathways underlying response to anti-IL-17A (AIN457; secukinumab) therapy differ across severe asthmatic patients

R. Strieter, T. Thornton-Wells, J. Laramie, 2017 .

SEQUENCE MAKES A DIFFERENCE: PARADOXICAL EFFECTS OF STRESS IN VIVO

C. Coopersmith, R. Hotchkiss, J. Cobb, 2004, Shock.

Aptamer Proteomics for Biomarker Discovery in Heart Failure with Reduced Ejection Fraction

J. McMurray, J. Rouleau, P. Jhund, 2022, medRxiv.

Whole Genome Sequencing Reveals a Widely Expressed Mutation (MYD88 L265P) with Oncogenic Activity in Waldenstrom's Macroglobulinemia

D. Skifter, S. Lincoln, J. Laramie, 2011 .

Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers.

B. Peters, Geoffrey B. Nilsen, P. Ng, 2014, Cancer research.

Framingham Heart Study genome-wide association: results for pulmonary function measures

G. O'Connor, D. Gottlieb, J. Wilk, 2007, BMC Medical Genetics.

Molecular Diagnostics in Sepsis: From Bedside to Bench

G. Stormo, R. Hotchkiss, T. Downey, 2006, Journal of the American College of Surgeons.

Translational precision medicine: an industry perspective

J. Millholland, J. Laramie, E. Ferrero, 2021, Journal of Translational Medicine.

MYD88 L265P somatic mutation in Waldenström's macroglobulinemia.

N. Harris, D. Skifter, S. Lincoln, 2012, The New England journal of medicine.

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism.

M. MacDonald, J. Gusella, R. Myers, 2005, Human molecular genetics.

Polymorphisms near EXOC4 and LRGUK on chromosome 7q32 are associated with Type 2 Diabetes and fasting glucose; The NHLBI Family Heart Study

I. Borecki, M. Province, J. Wilk, 2008, BMC Medical Genetics.

Artificial intelligence and machine learning in clinical development: a translational perspective

Jianying Hu, Sean Khozin, Pratik Shah, 2019, npj Digital Medicine.

Haplotypes and gene expression implicate the MAPT region for Parkinson disease

H. Shill, J. Growdon, S. Sherman, 2008, Neurology.

Evaluating the contribution of rare variants to type 2 diabetes and related traits using pedigrees

Tanya M. Teslovich, Kyle J. Gaulton, Y. J. Kim, 2017, Proceedings of the National Academy of Sciences.

Leptin Is Associated With Blood Pressure and Hypertension in Women From the National Heart, Lung, and Blood Institute Family Heart Study

I. Borecki, M. Province, M. Feitosa, 2009, Hypertension.

Global gene expression in neuroendocrine tumors from patients with the MEN1 syndrome

J. Cobb, J. Laramie, T. Lairmore, 2005, Molecular Cancer.

Sepsis gene expression profiling: Murine splenic compared with hepatic responses determined by using complementary DNA microarrays

G. Stormo, R. Hotchkiss, J. Cobb, 2002, Critical care medicine.

BMC Medicine

Christine Klein, Karen Ostergaard, Stuart, 2006 .

INJURY IN THE ERA OF GENOMICS

G. Stormo, R. Hotchkiss, M. Watson, 2001, Shock.

Sepiapterin reductase expression is increased in Parkinson's disease brain tissue

A. DeStefano, A. McKee, J. Wilk, 2007, Brain Research.

Whole blood and leukocyte RNA isolation for gene expression analyses.

Jason Laramie, Wenzhong Xiao, J Perren Cobb, 2004, Physiological genomics.

Relation of increased prebeta-1 high-density lipoprotein levels to risk of coronary heart disease.

Christian Zellner, Prakash Deedwania, L. Guey, 2011, The American journal of cardiology.

Reverse Engineering and Evaluation of Prediction Models for Progression to Type 2 Diabetes

Jignesh R. Parikh, Jason M. Laramie, Richard J. Willke, 2016, Journal of diabetes science and technology.

Surgical research reviewPhysiologic genomics

J. Cobb, J. Laramie, R. Townsend, 2006 .

Ten simple rules to power drug discovery with data science

Audrey Kauffmann, Birgit Schoeberl, Sophie Brachat, 2020, PLoS Comput. Biol..

Gene expression profiles of livers from thermally injured rats.

Marcus Spies, J Perren Cobb, M. Spies, 2004, Gene.

SEPSIS GENE EXPRESSION PROFILING II: EFFECT OF ANTIBIOTICS OVER TIME ON MURINE SPLENOCYTES AFTER CECAL LIGATION AND PUNCTURE.: 78

R. Hotchkiss, M. Watson, J. Cobb, 2001 .

Democratizing data at Novartis through clinical trial data access.

Gabriel S. Eichler, J. Laramie, J. Branson, 2022, Drug Discovery Today.

Functional genomics of critical illness and injury.

M. Province, J. Cobb, J. Laramie, 2002, Critical care medicine.

TRANSCRIPTIONAL PROFILES OF HUMAN EPITHELIAL CELLS IN RESPONSE TO HEAT: COMPUTATIONAL EVIDENCE FOR NOVEL HEAT SHOCK PROTEINS

J Perren Cobb, Gary D Stormo, G. Stormo, 2007, Shock.

SEPSIS GENE EXPRESSION PROFILING IV: CIRCULATING BLOOD TRANSCRIPTION PROFILES PREDICT PHENOTYPES IN MICE WITH ABDOMINAL SEPSIS OR INFLAMMATION: 98

G. Stormo, B. Brownstein, J. Cobb, 2003 .

Multiple Genes Influence BMI on Chromosome 7q31–34: The NHLBI Family Heart Study

I. Borecki, M. Province, J. Wilk, 2009, Obesity.

Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers.

B. Peters, Geoffrey B. Nilsen, P. Ng, 2014, Cancer research.

Arti ﬁ cial intelligence and machine learning in clinical development: a translational perspective

N. Schork, Jianying Hu, S. Khozin, 2022 .