D. Basketter

D. Basketter, D. Mougin, A. P. Walker, 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Predictive testing in contact dermatitis. Irritant dermatitis.

D. Basketter, F. Reynolds, M. York, 1997, Clinics in dermatology.

Test guidelines for the assessment of skin tolerance of potentially irritant cosmetic ingredients in man. European Cosmetic, Toiletry and Perfumery Association.

D. Basketter, D. Mougin, A. P. Walker, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Patch tests versus use tests in skin irritation risk assessment

D. Basketter, F. Reynolds, E. Whittle, 1998, Contact dermatitis.

Toxicology of Contact Dermatitis: Allergy, Irritancy and Urticaria

D. Basketter, I. Kimber, Carolyn Willis, 1999 .

Immune responses to contact allergens: novel approaches to hazard evaluation.

D. Basketter, I. Kimber, R. Dearman, 1999, Toxicology letters.

Nickel, chromium and cobalt in consumer products: revisiting safe levels in the new millennium

D. Basketter, G. Angelini, T. Menné, 2003, Contact dermatitis.

Preservatives and Skin Sensitization Quantitative Risk Assessment

D. Basketter, F. Gerberick, C. Ryan, 2008, Dermatitis : contact, atopic, occupational, drug.

Ethnic variation in the skin irritation response

D. Basketter, E. Whittle, V. Foy, 2001, Contact dermatitis.

Predictive Tests for Irritants and Allergens: Human, Animal, and In Vitro Tests

D. Basketter, I. Kimber, J. Ezendam, 2020, Contact Dermatitis.

Predictive Tests for Irritants and Allergens: Human, Animal, and In Vitro Tests

D. Basketter, I. Kimber, J. Ezendam, 2020, Contact Dermatitis.

Integrated Testing Strategies ( ITS ) for Safety Assessment 1

A. M. Api, L. Smirnova, J. Pitchford, 2014 .

Dichloronitrobenzene: a reappraisal of its skin sensitization potential

D. Basketter, I. Kimber, R. Dearman, 1996, Contact dermatitis.

Dinitrohalobenzenes: evaluation of relative skin sensitization potential using the local lymph node assay

D. Basketter, I. Kimber, R. Dearman, 1997, Contact dermatitis.

Irritant dermatitis, irritancy and its role in allergic contact dermatitis

D. Basketter, J. McFadden, H. Smith, 2002, Clinical and experimental dermatology.

Activation of Human Dendritic Cells by p-Phenylenediamine

K. L. Mathews, D. Basketter, B. K. Park, 2007, Journal of Pharmacology and Experimental Therapeutics.

The impact of vehicle on assessment of relative skin sensitization potency of 1,4-dihydroquinone in the local lymph node assay.

D. Basketter, I. Kimber, R. Dearman, 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Skin sensitization quantitative risk assessment: A review of underlying assumptions.

D. Basketter, B. Safford, 2016, Regulatory toxicology and pharmacology : RTP.

Diisocyanates, occupational asthma and IgE antibody: implications for hazard characterization

D. Basketter, I. Kimber, R. Dearman, 2014, Journal of applied toxicology : JAT.

Local lymph node assay: use in hazard and risk assessment

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

The performance of the local lymph node assay with chemicals identified as contact allergens in the human maximization test.

D. Basketter, I. Kimber, E. Scholes, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Atopy and contact allergy to fragrance: allergic reactions to the fragrance mix I (the Larsen mix)

D. Buckley, D. Basketter, I. White, 2008, Contact dermatitis.

Skin sensitisation.

A. Worth, D. Basketter, G. Gerberick, 2005, Alternatives to laboratory animals : ATLA.

Does hapten exposure predispose to atopic disease? The hapten-atopy hypothesis.

D. Basketter, I. Kimber, J. McFadden, 2009, Trends in immunology.

Immunogenic properties of rapidly digested food proteins following gavage exposure of mice: a comparison of ovalbumin with a potato acid phosphatase preparation.

D. Basketter, I. Kimber, J. G. Kenna, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Characterization of antibody responses induced in rodents by exposure to food proteins: influence of route of exposure.

D. Basketter, I. Kimber, R. Dearman, 2001, Toxicology.

Divergent antibody isotype responses induced in mice by systemic exposure to proteins: a comparison of ovalbumin with bovine serum albumin.

D. Basketter, I. Kimber, R. Dearman, 2000, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Selection of Chemicals for the Development and Evaluation of In Vitro Methods for Skin Sensitisation Testing

C. Rovida, D. Basketter, L. Tosti, 2009 .

Results with OECD recommended positive control sensitizers in the maximization, Buehler and local lymph node assays.

D. Basketter, P. Botham, I. Kimber, 1993, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Fragrance sensitisers: Is inhalation an allergy risk?

D. Basketter, I. Kimber, 2015, Regulatory toxicology and pharmacology : RTP.

Immediate contact reactions to chemicals in the fragrance mix and a study of the quenching action of eugenol

D. Basketter, R. Safford, C. Allenby, 1990, The British journal of dermatology.

Epicutaneous challenge with protease allergen requires its protease activity to recall TH2 and TH17/TH22 responses in mice pre-sensitized via distant skin

D. Basketter, H. Yokozeki, H. Sakaguchi, 2021, Journal of immunotoxicology.

The impact of LLNA group size on the identification and potency classification of skin sensitizers: a review of published data

D. Basketter, I. Kimber, C. Ryan, 2009, Cutaneous and ocular toxicology.

Total dose defines the incidence of percutaneous IgE/IgG1 mediated immediate‐type hypersensitivity caused by papain

D. Basketter, H. Sakaguchi, A. Ogasawara, 2020, Journal of applied toxicology : JAT.

Skin Sensitisation, Adverse Outcome Pathways and Alternatives

D. Basketter, 2016, Alternatives to laboratory animals : ATLA.

Dermal Toxicity: Skin Sensitization

D. Basketter, S. Casati, 2014 .

Local lymph node assay: validation assessment for regulatory purposes.

D. Basketter, I. Kimber, C. Ryan, 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Building confidence in skin sensitisation potency assessment using new approach methodologies report of the 3rd EPAA Partners Forum, Brussels, 28th October 2019.

D. Basketter, J. Bridges, M. Jacobs, 2020, Regulatory toxicology and pharmacology : RTP.

In vitro RHE skin sensitisation assays: Applicability to challenging substances.

D. Basketter, A. Irizar, B. Hubesch, 2019, Regulatory toxicology and pharmacology : RTP.

Are skin sensitisation test methods relevant for proteins?

D. Basketter, I. Kimber, 2018, Regulatory toxicology and pharmacology : RTP.

Phthalic anhydride: Illustrating a conundrum in chemical allergy

D. Basketter, I. Kimber, 2016, Journal of immunotoxicology.

REACH and Immunotoxicology

D. Basketter, L. H. Rossi, 2014 .

The local lymph node assay in 2014.

D. Basketter, I. Kimber, G. Gerberick, 2014, Dermatitis : contact, atopic, occupational, drug.

Inter‐relationships between different classes of chemical allergens

D. Basketter, I. Kimber, R. Dearman, 2013, Journal of applied toxicology : JAT.

Assessing the potency of respiratory allergens: uncertainties and challenges.

D. Basketter, I. Kimber, 2011, Regulatory toxicology and pharmacology : RTP.

Dermal Toxicology of Cosmetics and Body‐Care Products

D. Basketter, L. Lea, 2009 .

Strong irritants masquerading as skin allergens: the case of benzalkonium chloride

D. Basketter, I. White, M. Marriott, 2004, Contact dermatitis.

Designation of substances as skin sensitizing chemicals: a commentary

D. Basketter, I. Kimber, R. Dearman, 2003, Human & experimental toxicology.

Protein–Hapten Binding: Challenges and Limitations for In Vitro Skin Sensitization Assays

D. Basketter, A. Dell, H. Morris, 2003 .

Utility of historical vehicle‐control data in the interpretation of the local lymph node assay

D. Basketter, I. Kimber, G. Gerberick, 2003, Contact dermatitis.

Predictive testing in contact all_ergy: facts and future

D. Basketter, I. Kimber, 2001, Allergy.

Quenching: fact or fiction?

D. Basketter, 2000, Contact dermatitis.

Irritant thresholds in subjects withcolophony allergy

D. Basketter, J. Mcfadden, J. McFadden, 2000, Contact dermatitis.

Investigating protein haptenation mechanisms of skin sensitisers using human serum albumin as a model protein.

D. Basketter, A. Dell, H. Morris, 2007, Toxicology in vitro : an international journal published in association with BIBRA.

Can currently available non-animal methods detect pre and pro-haptens relevant for skin sensitization?

Silvia Casati, Jean-Pierre Lepoittevin, Andrew P Worth, 2016, Regulatory toxicology and pharmacology : RTP.

Skin Sensitization Tests: The LLNA and the RhE IL-18 Potency Assay.

D. Basketter, E. Corsini, I. Kimber, 2021, Methods in molecular biology.

Why does allergic contact dermatitis exist?

D. Basketter, J. Mcfadden, I. Kimber, 2013, The British journal of dermatology.

Sodium metabisulfite as a contact allergen – an example of a rare chemical mechanism for protein modification

D. Roberts, D. Basketter, I. Kimber, 2012, Contact dermatitis.

Skin sensitization to cinnamic alcohol: the role of skin metabolism.

D. Basketter, 1992, Acta dermato-venereologica.

p‐Phenylenediamine allergy: the role of Bandrowski's base

D. Basketter, J. Mcfadden, J. McFadden, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Toward an evidence-based dermatotoxicology

T. Hartung, D. Basketter, S. Hoffmann, 2012 .

Enzymes and sensitization via skin exposure: A critical analysis.

D. Basketter, I. Kimber, 2021, Regulatory toxicology and pharmacology : RTP.

Skin and respiratory chemical allergy: confluence and divergence in a hybrid adverse outcome pathway.

D. Basketter, A. Poole, I. Kimber, 2018, Toxicology research.

The hapten–atopy hypothesis III: the potential role of airborne chemicals

D. Basketter, J. Mcfadden, I. Kimber, 2014, The British journal of dermatology.

Skin irritation thresholds in hairdressers: implications for the development of hand dermatitis

D. Basketter, J. Mcfadden, H. Smith, 2002, The British journal of dermatology.

Contact allergy, irritancy and ‘danger’

D. Basketter, J. Mcfadden, J. McFadden, 2000, Contact dermatitis.

Immediate contact reactions to fragrance mix constituents and Myroxylon pereirae resin

D. Basketter, R. Rycroft, J. McFadden, 2004, Contact dermatitis.

Metal Exposure Regulations and Their Effect on Allergy Prevention

D. Basketter, K. Heim, 2018 .

Fragrance allergy in patients with hand eczema – a clinical study

D. Basketter, M. Bruze, S. Heydorn, 2003, Contact dermatitis.

The local lymph node assay: An interlaboratory evaluation of Interleukin 6 (IL‐6) production by draining lymph node cells

D. Basketter, I. Kimber, R. Dearman, 1994, Journal of applied toxicology : JAT.

Characteristics of antibody responses induced in mice by protein allergens.

D. Basketter, I. Kimber, R. Dearman, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Classification of Chemical Allergens According to Cytokine Secretion Profiles of Murine Lymph Node Cells

D. Basketter, S. Smith, I. Kimber, 1997, Journal of applied toxicology : JAT.

Studies on non‐immune immediate contact reactions in an unselected population

K. Wilhelm, D. Basketter, 1996, Contact dermatitis.

Relevance of sensitization to occupational allergy and asthma in the detergent industry

D. Basketter, F. Kruszewski, K. Sarlo, 2012, Journal of immunotoxicology.

The cosmetic allergy conundrum: inference of an immunoregulatory response to cosmetic allergens

D. Basketter, I. Kimber, I. White, 2013, Contact dermatitis.

The Local Lymph Node Assay (LLNA)

C. Rovida, D. Basketter, I. Kimber, 2012, Current protocols in toxicology.

An evaluation of the suitability of benzocaine as a positive control skin sensitizer

D. Basketter, J. Montelius, E. Scholes, 1995, Contact dermatitis.

Does Irritation Potency Contribute to the Skin Sensitization Potency of Contact Allergens?

D. Basketter, I. Jowsey, D. Kan-King-Yu, 2007, Cutaneous and ocular toxicology.

Activation of T-cells from allergic patients and volunteers by p-phenylenediamine and Bandrowski's base.

M. Pirmohamed, D. Basketter, D. Naisbitt, 2008, The Journal of investigative dermatology.

Characterization of chemical allergens as a function of divergent cytokine secretion profiles induced in mice.

D. Basketter, I. Kimber, R. Dearman, 1996, Toxicology and applied pharmacology.

Updating exposure assessment for skin sensitization quantitative risk assessment for fragrance materials.

A. M. Api, D. Basketter, H. Greim, 2020, Regulatory toxicology and pharmacology : RTP.

Perforin, COVID‐19 and a possible pathogenic auto‐inflammatory feedback loop

P. Simmonds, D. Basketter, I. Kimber, 2021, Scandinavian journal of immunology.

Why judiciously timed anti-IL 6 therapy may be of benefit in severe COVID-19 infection

D. Basketter, I. Kimber, J. McFadden, 2020, Autoimmunity Reviews.

Enzymes, detergents and skin: facts and fantasies

D. Basketter, J. English, I. White, 2008, The British journal of dermatology.

Identification of immunotoxic effects of chemicals and assessment of their relevance to man.

D. Basketter, C. Lambré, P. Botham, 1988, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Perforin and resistance to SARS coronavirus 2

P. Simmonds, D. Basketter, I. Kimber, 2020, Journal of Allergy and Clinical Immunology.

Behaviour of chemical respiratory allergens in novel predictive methods for skin sensitisation.

D. Basketter, A. Poole, I. Kimber, 2017, Regulatory toxicology and pharmacology : RTP.

Chemical allergy in humans: Fresh perspectives

D. Basketter, J. Thyssen, I. Kimber, 2014, Journal of immunotoxicology.

Selective induction of type 2 cytokines following topical exposure of mice to platinum salts.

D. Basketter, I. Kimber, R. Dearman, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Measurement of CD4+ and CD8+ T-lymphocyte cytokine secretion and gene expression changes in p-phenylenediamine allergic patients and tolerant individuals.

Andrew A. White, Dominic P. Williams, M. Pirmohamed, 2010, The Journal of investigative dermatology.

Reduced allergy rates in atopic eczema to contact allergens used in both skin products and foods: atopy and the ‘hapten‐atopy hypothesis’

D. Basketter, I. Kimber, Jonathan M L White, 2008, Contact dermatitis.

T helper cell 2 immune skewing in pregnancy/early life: chemical exposure and the development of atopic disease and allergy

D. Basketter, J. Thyssen, J. Mcfadden, 2015, The British journal of dermatology.

Intra‐individual variation of irritant threshold and relationship to transepidermal water loss measurement of skin irritation

D. Basketter, J. Mcfadden, M. Rowson, 2004, Contact dermatitis.

Chemical respiratory allergy: classification and labelling.

D. Basketter, I. Kimber, R. Roggeband, 2001, Toxicology.

Minimum eliciting patch test concentrations of cobalt

D. Basketter, C. Allenby, D. Basketter, 1989, Contact dermatitis.

Differential ability of occupational chemical contact and respiratory allergens to cause immediate and delayed dermal hypersensitivity reactions in mice.

D. Basketter, I. Kimber, R. Dearman, 1992, International archives of allergy and immunology.

Gene expression analysis of EpiDerm following exposure to SLS using cDNA microarrays.

D. Kelsell, D. Basketter, V. Baker, 2001, Toxicology in vitro : an international journal published in association with BIBRA.

Predictive testing for respiratory sensitization in the mouse.

D. Basketter, I. Kimber, R. Dearman, 1996, Toxicology letters.

Experimental assessment of the sensitizing properties of formaldehyde.

D. Basketter, I. Kimber, R. Dearman, 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Identification of Chemical Respiratory Allergens: Dose-Response Relationships in the Mouse IgE Test

D. Basketter, I. Kimber, R. Dearman, 1995 .

Serological responses induced in mice by immunogenic proteins and by protein respiratory allergens.

D. Basketter, I. Kimber, R. Dearman, 1994, Toxicology letters.

Langerhans cells, antigen presentation, and the diversity of responses to chemical allergens.

S. Gould, D. Basketter, I. Kimber, 1992, The Journal of investigative dermatology.

Variable effects of chemical allergens on serum ige concentration in mice. Preliminary evaluation of a novel approach to the identification of respiratory sensitizers

D. Basketter, I. Kimber, R. Dearman, 1992, Journal of applied toxicology : JAT.

The cellular and molecular basis for divergent allergic responses to chemicals.

D. Basketter, I. Kimber, R. Dearman, 1992, Chemico-biological interactions.

Distribution and number of epidermal growth factor receptors in skin is related to epithelial cell growth.

D. Basketter, M. Green, J. Couchman, 1983, Developmental biology.

Addressing the conundrums of p‐phenylenediamine hair dye allergy by applying Friedmann's principles of contact sensitization

D. Basketter, I. White, F. Ferguson, 2019, Contact dermatitis.

Methyldibromoglutaronitrile: skin sensitization and quantitative risk assessment

D. Basketter, 2010, Cutaneous and ocular toxicology.

Investigation of the threshold for allergic reactivity to chromium

D. Basketter, L. Horev, A. Ingber, 2001, Contact dermatitis.

Identification of fragrances relevant to hand eczema

D. Basketter, S. Heydorn, J. Johansen, 2002 .

Susceptibility to skin stinging, non‐immunologic contact urticaria and acute skin irritation; is there a relationship?

D. Basketter, E. Whittle, J. Coyerly, 1998, Contact dermatitis.

Fragrance Skin Sensitization Evaluation and Human Testing: 30-Year Experience

A. M. Api, D. Basketter, M. Lavelle, 2020, Dermatitis : contact, atopic, occupational, drug.

The Role of Non-Covalent Protein Binding in Skin Sensitisation Potency of Chemicals

D. Basketter, S. Gutsell, M. Aleksić, 2007, Cutaneous and ocular toxicology.

The Local Lymph Node Assay

D. Basketter, I. Kimber, G. Gerberick, 2019, Dermatotoxicology Methods: The Laboratory Worker’s Vade Mecum.

Quantitative risk assessment for skin sensitization: Success or failure?

D. Basketter, I. Kimber, G. Gerberick, 2017, Regulatory toxicology and pharmacology : RTP.

Hexyl cinnamal: consideration of skin-sensitizing properties and suitability as a positive control

D. Basketter, I. Kimber, I. White, 2015, Cutaneous and ocular toxicology.

Consideration of criteria required for assignment of a (skin) sensitiser a substance of very high concern (SVHC) under the REACH regulation.

D. Basketter, I. Kimber, 2014, Regulatory toxicology and pharmacology : RTP.

Skin irritation, false positives and the local lymph node assay: a guideline issue?

D. Basketter, I. Kimber, 2011, Regulatory toxicology and pharmacology : RTP.

The reduced local lymph node assay: the impact of group size

G. Patlewicz, D. Basketter, I. Kimber, 2008, Journal of applied toxicology : JAT.

Chemical respiratory sensitizers: Activity in a non-standard local lymph node assay (LLNA)

D. Basketter, I. Kimber, R. Dearman, 2007 .

Elicitation response characteristics to permanent hair dye in paraphenylenediamine‐allergic volunteers

D. Basketter, I. Jowsey, J. McFadden, 2006, Contact dermatitis.

Biocides: Characterization of the Allergenic Hazard of Methylisothiazolinone

D. Basketter, C. Lidén, A. Boman, 2003 .

Asymmetry of the hexose transfer system in human erythrocytes. Comparison of the effects of cytochalasin B, phloretin and maltose as competitive inhibitors.

D. Basketter, W. F. Widdas, 1978, The Journal of physiology.

Analysis of interleukin 12 protein production and mRNA expression in mice exposed topically to chemical allergens.

D. Basketter, I. Kimber, R. Dearman, 1999, Toxicology.

A QSAR evaluation of existing contact allergy database

M. Cronin, D. Basketter, 1993 .

THE MOUSE IgE TEST: INTERLABORATORY EVALUATION AND COMPARISON OF BALB/c AND C57BL/6 STRAIN MICE

D. Basketter, G. Ladics, I. Kimber, 1998 .

Irritant threshold and histological response of epidermis to irritant application

D. Basketter, J. Mcfadden, E. Calonje, 2004, Contact dermatitis.

Incidence and prevalence of para-phenylenediamine allergy in an adult Thai population: a public health problem

D. Basketter, J. McFadden, P. Kullavanijaya, 2007 .

Allergic Contact Dermatitis

G Frank Gerberick, Ian Kimber, David A Basketter, 1998, Springer Berlin Heidelberg.

Contact allergenic potency: correlation of human and local lymph node assay data.

I Kimber, G F Gerberick, R J Dearman, 2001, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Allergic contact dermatitis from ethoxymethylenemalononitrile in an agrochemical chemist

S. Wakelin, D. Basketter, R. Rycroft, 1998, Contact dermatitis.

Alternative Methods for Skin Sensitisation Testing

Emanuela Corsini, Jean-Pierre Lepoittevin, Maria Ponec, 1996 .

Chemical photoallergy: photobiochemical mechanisms, classification, and risk assessments.

A. M. Api, S. Onoue, D. Basketter, 2017, Journal of dermatological science.

Skin sensitization testing in potency and risk assessment.

I Kimber, D A Basketter, W Steiling, 2001, Toxicological sciences : an official journal of the Society of Toxicology.

Skin sensitization potency of methyl methacrylate in the local lymph node assay: comparisons with guinea‐pig data and human experience

Ian Kimber, David A Basketter, D. Basketter, 2006, Contact dermatitis.

Nickel, cobalt and chromium in consumer products: a role in allergic contact dermatitis?

D. Basketter, G. Briatico-Vangosa, W. Bontinck, 1993, Contact dermatitis.

The biocide polyhexamethylene biguanide remains an uncommon contact allergen

J. Geier, A. Schnuch, W. Uter, 2007, Contact dermatitis.

In vitro skin irritation: facts and future. State of the art review of mechanisms and models.

David A Basketter, D. Basketter, T. Welss, 2004, Toxicology in vitro : an international journal published in association with BIBRA.

Alternative approaches to the identification and characterization of chemical allergens.

I Kimber, R J Dearman, D A Basketter, 2001, Toxicology in vitro : an international journal published in association with BIBRA.

Investigation of the skin sensitizing activity of linalool

G. Patlewicz, D. Basketter, C. Pease, 2002, Contact dermatitis.

Mechanistic applicability domain classification of a local lymph node assay dataset for skin sensitization.

Petra S Kern, Grace Patlewicz, David W Roberts, 2007, Chemical research in toxicology.

Chemistry of contact allergens and irritants.

D. Basketter, 1998, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

The chemistry of contact allergy: why is a molecule allergenic?

David Basketter, D. Basketter, A. Karlberg, 1995, Contact dermatitis.

Combined effects of irritants and allergens

T. Agner, D. Basketter, A. Vølund, 2002, Contact dermatitis.

The value and limitations of rechallenge in the guinea pig maximization test

D. Basketter, K. Andersen, S. Frankild, 1996, Contact dermatitis.

Intermittent exposure to low‐concentration paraphenylenediamine can be equivalent to single, higher‐dose exposure

D. Basketter, D. Sanders, J. McFadden, 2007, Contact dermatitis.

Contact allergy to isoeugenol and its derivatives: problems with allergen substitution

D. Buckley, D. Basketter, A. Goossens, 2004, Contact dermatitis.

Clinical allergy to cocamidopropyl betaine: reactivity to cocamidopropylamine and lack of reactivity to 3‐dimethylaminopropylamine

D. Basketter, I. White, J. McFadden, 2001, Contact dermatitis.

Skin sensitization risk assessment: a comparative evaluation of 3 isothiazolinone biocides

I Kimber, D A Basketter, D. Basketter, 1999, Contact dermatitis.

Provocative use tests in CAPB‐allergic subjects with CAPB‐containing product

D. Basketter, T. Diepgen, M. Fartasch, 1999, Contact dermatitis.

Contact sensitization: A new approach to risk assessment

Ian Kimber, David A. Basketter, D. Basketter, 1997 .

Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects

A. M. Api, T. L. Diepgen, D. A. Basketter, 2011, Cellular and Molecular Life Sciences.

Studies of the quenching phenomenon in delayed contact hypersensitivity reactions

D A Basketter, D. Basketter, C F Allenby, 1991, Contact dermatitis.

Skin sensitisation testing--new perspectives and recommendations.

I Kimber, W Steiling, D. Basketter, 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The identification of photoallergic potential in the local lymph node assay.

D A Basketter, D. Basketter, W W Lovell, 1991, Photodermatology, photoimmunology & photomedicine.

Positive rates to propyl gallate on patch testing: a change in trend

D. Basketter, J. McFadden, I. White, 2007, Contact dermatitis.

Analysis of para‐phenylenediamine allergic patients in relation to strength of patch test reaction

D. Basketter, R. Rycroft, J. Mcfadden, 2005, The British journal of dermatology.

The importance of exposure estimation in the assessment of skin sensitization risk

G F Gerberick, D A Basketter, M K Robinson, 2000, Contact dermatitis.

Understanding fragrance allergy using an exposure‐based risk assessment approach

S. Felter, D. Basketter, I. White, 2001, Contact dermatitis.

Methyldibromoglutaronitrile: An Increasingly Important Allergen in the UK

D. Basketter, M. Beck, D. Ramlogan, 2004, Exogenous Dermatology.

Protein binding and metabolism influence the relative skin sensitization potential of cinnamic compounds.

D. Basketter, S. Hotchkiss, D. Hinselwood, 2004, Chemical Research in Toxicology.

Dose–time relationships for elicitation of contact allergy to para‐phenylenediamine

D. Basketter, L. Blaikie, J. McFadden, 2002, Contact dermatitis.

Comparison of human skin irritation and photo-irritation patch test data with cellular in vitro assays and animal in vivo data

D. Basketter, M. Liebsch, K. Kejlová, 2008 .

COMBINED EFFECTS OF IRRITANTS AND ALLERGENS: 20

T. Agner, D. Basketter, A. Vølund, 2002 .

Thresholds in contact sensitization: theoretical and practical considerations.

I Kimber, G F Gerberick, D A Basketter, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The effect of patch duration on the elicitation of para‐phenylenediamine contact allergy

S. Wakelin, D. Basketter, J. Mcfadden, 1998, Contact dermatitis.

An arm immersion model of compromised skin

D. Basketter, C. Allenby, 1993, Contact dermatitis.

Hapten–protein binding: from theory to practical application in the in vitro prediction of skin sensitization

G Frank Gerberick, David A Basketter, Camilla K Pease, 2005, Contact dermatitis.

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients.

G Frank Gerberick, Anne Marie Api, David A Basketter, 2008, Regulatory toxicology and pharmacology : RTP.

The local lymph node assay and the assessment of relative potency: status of validation

Frank Gerberick, Ian Kimber, David A Basketter, 2007, Contact dermatitis.

Predictive identification of human skin sensitization thresholds

Frank Gerberick, Ian Kimber, Bob Safford, 2005, Contact dermatitis.

Contact Allergy Risk Assessment

D. Basketter, 1993 .

Patch test frequency to p‐phenylenediamine: follow up over the last 6 years

D. Basketter, R. Rycroft, I. White, 2007, Contact dermatitis.

The identification and classification of skin irritation hazard by a human patch test.

D. Basketter, M. York, E. Whittle, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

A general population from Thailand: incidence of common allergens with emphasis on para‐phenylenediamine

D. Basketter, J. Mcfadden, D. Jeffries, 2007, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Dendritic Cells as a Tool for the Predictive Identification of Skin Sensitisation Hazard

Valérie Zuang, Silvia Casati, Thomas Hartung, 2005, Alternatives to laboratory animals : ATLA.

The Report and Recommendations of ECVAM Workshop 51 1,2

T. Hartung, D. Basketter, A. Cavani, 2005 .

Classification criteria for skin‐sensitizing chemicals: a commentary

D A Basketter, D. Basketter, M. Flyvholm, 1999, Contact dermatitis.

Activity of human contact allergens in the murine local lymph node assay

I Kimber, G F Gerberick, R J Dearman, 2000, Contact dermatitis.

The local lymph node assay: developments and applications.

I Kimber, R J Dearman, D A Basketter, 1994, Toxicology.

The murine local lymph node assay: results of an inter-laboratory trial.

T. Gray, D. Basketter, P. Botham, 1991, Toxicology letters.

Citral a fragrance allergen and irritant

D. Basketter, M. Bruze, S. Heydorn, 2003, Contact dermatitis.

Oral tolerance to contact allergens: a common occurrence? A review

D. Basketter, I. Kimber, I. Jowsey, 2007, Contact dermatitis.

A review of critical factors in the conduct and interpretation of the human repeat insult patch test.

Anne Marie Api, David A Basketter, Ian Jowsey, 2008, Regulatory toxicology and pharmacology : RTP.

Skin sensitisation, vehicle effects and the local lymph node assay.

I Kimber, G F Gerberick, D A Basketter, 2001, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Identification of metal allergens in the local lymph node assay.

I Kimber, G F Gerberick, R J Dearman, 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

REVIEW Skin sensitization: risk assessment

D. Basketter, 1998, International journal of cosmetic science.

The effect of repeated open exposure to low levels of nickel on compromised hand skin of nickel‐allergic subjects

D. Basketter, C. Allenby, 1994, Contact dermatitis.

The impact of exposure variables on the induction of skin sensitization

D. Basketter, I. Jowsey, B. Safford, 2006, Contact dermatitis.

Human potency predictions for aldehydes using the local lymph node assay

I Kimber, G F Gerberick, R J Dearman, 2001, Contact dermatitis.

Threshold for classification as a skin sensitizer in the local lymph node assay: a statistical evaluation.

I Kimber, R J Dearman, D A Basketter, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Strategies for identifying false positive responses in predictive skin sensitization tests.

I Kimber, G F Gerberick, D A Basketter, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

An international evaluation of the murine local lymph node assay and comparison of modified procedures.

J Hilton, I Kimber, G F Gerberick, 1995, Toxicology.

Skin sensitization--a critical review of predictive test methods in animals and man.

D A Basketter, T Maurer, D. Basketter, 1991, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Skin sensitization to eugenol and isoeugenol in mice: possible metabolic pathways involving ortho-quinone and quinone methide intermediates.

D W Roberts, D A Basketter, D. Roberts, 1997, Chemical research in toxicology.

Further investigation of the prohapten concept: reactions to benzene derivatives in man

D. Basketter, C. Lidén, 1992, Contact dermatitis.

Possible origin of the skin sensitization potential of isoeugenol and related compounds

D A Basketter, M D Barratt, D. Basketter, 1992, Contact dermatitis.

Categorization of Chemicals According to Their Relative Human Skin Sensitizing Potency

João Barroso, Andreas Schepky, Sebastian Hoffmann, 2014, Dermatitis : contact, atopic, occupational, drug.

The local lymph node assay: a viable alternative to currently accepted skin sensitization tests.

I Kimber, G F Gerberick, D A Basketter, 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The classification of skin irritants by human patch test.

D. Basketter, M. Chamberlain, M. Rowson, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Skin sensitization thresholds: determination in predictive models.

D. Basketter, G. Gerberick, M. Potokar, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Evaluation of protein allergenic potential in mice: dose–response analyses

I Kimber, R J Dearman, D A Basketter, 2003, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Protein Allergenicity: Mouse Models

D. Basketter, I. Kimber, R. Dearman, 2002 .

Contact allergy: the role of skin chemistry and metabolism

D A Basketter, D. Basketter, C K Smith Pease, 2003, Clinical and experimental dermatology.

Determination of skin irritation potential in the human 4‐h patch test

David A Basketter, D. Basketter, M. Robinson, 2004, Contact dermatitis.

Application of the risk assessment paradigm to the induction of allergic contact dermatitis.

G Frank Gerberick, David A Basketter, Susan P Felter, 2003, Regulatory toxicology and pharmacology : RTP.

Comparison of the local lymph node assay with the guinea-pig maximization test for the detection of a range of contact allergens.

D A Basketter, D. Basketter, E W Scholes, 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

A critical commentary and updating of the guinea pig maximization test

D. Basketter, A. Kligman, 1995, Contact dermatitis.

Validity and ethics of the human 4‐h patch test as an alternative method to assess acute skin irritation potential

D A Basketter, M K Robinson, D. Basketter, 2001, Contact dermatitis.

Application of a 4‐h human patch test method for comparative and investigative assessment of skin irritation

D. Basketter, M. Robinson, M. Perkins, 1998, Contact dermatitis.

Cross-reactions among hair dye allergens

D. Basketter, J. English, 2009, Cutaneous and ocular toxicology.

PROTEIN ALLERGENS: THE IMPORTANCE OF SKIN AS A ROUTE OF EXPOSURE

D. Basketter, I. White, C. K. Smith Pease, 2002 .

Individual, ethnic and seasonal variability in irritant susceptibility of skin: the implications for a predictive human patch test

K. Wilhelm, D. Basketter, J. McFadden, 1996, Contact dermatitis.

Thresholds, dose–response relationships and dose metrics in allergic contact dermatitis

D. Basketter, I. Kimber, 2008, British Journal of Dermatology.

Skin as a route of exposure to protein allergens

D. Basketter, I. White, C. K. Smith Pease, 2002, Clinical and experimental dermatology.

Integrated Testing Strategies (ITS) for safety assessment.

Thomas Hartung, Andreas Schepky, Mardas Daneshian, 2015, ALTEX.

Chemical respiratory allergy: reverse engineering an adverse outcome pathway.

Darrell R Boverhof, Ian Kimber, David A Basketter, 2014, Toxicology.

Dendritic cells and skin sensitization: biological roles and uses in hazard identification.

G Frank Gerberick, Ian Kimber, David A Basketter, 2007, Toxicology and applied pharmacology.

A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.

T. Knudsen, J. Jaworska, G. Patlewicz, 2012, ALTEX.

Consensus report on the future of animal-free systemic toxicity testing.

Mardas Daneshian, Thomas B Knudsen, Francois Busquet, 2014, ALTEX.

Polyhexamethylenebiguanide: a relevant contact allergen?

J. Geier, A. Schnuch, D. Basketter, 2000, Contact Dermatitis.

The Practical Approach

D. Basketter, A. Goossens, A. Karlberg, 1998 .

A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses

I Kimber, R J Dearman, D A Basketter, 1999, Journal of applied toxicology : JAT.

A review of the scientific basis for uncertainty factors for use in quantitative risk assessment for the induction of allergic contact dermatitis

G Frank Gerberick, David A Basketter, Susan P Felter, 2002, Contact dermatitis.

Use of the local lymph node assay for the estimation of relative contact allergenic potency

I. Kimber, D. Basketter, P. Evans, 2000, Contact dermatitis.

Influence of application vehicle on skin sensitization to methylchloroisothiazolinone/methylisothiazolinone: an analysis using the local lymph node assay

D. Basketter, I. Kimber, R. Dearman, 1999, Contact dermatitis.

Assessment of the skin sensitization potential of topical medicaments using the local lymph node assay: an interlaboratory evaluation.

J Hilton, I Kimber, G F Gerberick, 1998, Journal of toxicology and environmental health. Part A.

A re-appraisal of the skin-sensitizing activity of 2,4-dinitrothiocyanobenzene.

D. Basketter, I. Kimber, R. Dearman, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Harnessing co‐operative immune augmentation by contact allergens to enhance the efficacy of viral vaccines

D. Basketter, I. Kimber, I. White, 2020, Contact dermatitis.

Extra domain A-positive fibronectin-positive feedback loops and their association with cutaneous inflammatory disease.

D. Basketter, I. Kimber, R. Dearman, 2011, Clinics in dermatology.

Regulatory classification of substances oxidized to skin sensitizers on exposure to air

D. Basketter, A. Goossens, A. Karlberg, 1999, Contact dermatitis.

Proteomic analysis of the response of EpiDerm cultures to sodium lauryl sulphate.

D. Basketter, S. Fletcher, 2006, Toxicology in vitro : an international journal published in association with BIBRA.

Allergen‐induced changes in interleukin 1β (iL‐1β) mRNA expression by human blood‐derived dendritic cells: inter‐individual differences and relevance for sensitization testing

I Kimber, R J Dearman, D A Basketter, 2001, Journal of applied toxicology : JAT.

Classification of contact allergens according to potency: proposals.

I Kimber, G F Gerberick, D A Basketter, 2003, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The local lymph node assay: past, present and future

Ian Kimber, D. Basketter, I. Kimber, 2002, Contact dermatitis.

Factors affecting thresholds in allergic contact dermatitis: safety and regulatory considerations

D. Basketter, P. Evans, G. Gerberick, 2002, Contact dermatitis.

Local lymph node assay responses to paraphenylenediamine: intra‐ and inter‐laboratory evaluations

I. Kimber, D. Basketter, I. Kimber, 1999, Journal of applied toxicology : JAT.

Temporal stability of local lymph node assay responses to hexyl cinnamic aldehyde

Ian Kimber, D. Basketter, P. Evans, 1998, Journal of applied toxicology : JAT.

5.21 – Contact Hypersensitivity*

D. A. Basketter, D. Basketter, 2010 .

The Potential Use of Non-invasive Methods in the Safety Assessment of Cosmetic Products

V. Rogiers, J. Lévêque, P. Elsner, 1999, Alternatives to laboratory animals : ATLA.

Structure–activity relationships for selected fragrance allergens

G. Patlewicz, D. Basketter, J. Lepoittevin, 2002, Contact dermatitis.

Further evaluation of the local lymph node assay in the final phase of an international collaborative trial.

J Hilton, I Kimber, G F Gerberick, 1996, Toxicology.

Investigation of induced changes in interleukin 1beta mRNA expression by cultured human dendritic cells as an in vitro approach to skin sensitization testing.

I Kimber, D A Basketter, Dearman, 2000, Toxicology in vitro : an international journal published in association with BIBRA.

3.4. Skin Sensitisation

Silvia Casati, Andrew P. Worth, G. Frank Gerberick, 2005 .

The murine local lymph node assay: a commentary on collaborative studies and new directions.

I Kimber, D A Basketter, D. Basketter, 1992, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Cytokine endpoints for the local lymph node assay: consideration of interferon‐γ and interleukin 12

I. Kimber, D. Basketter, I. Kimber, 1999, Journal of applied toxicology : JAT.

Chemical allergy: considerations for the practical application of cytokine profiling.

Neil Humphreys, Ian Kimber, David A Basketter, 2003, Toxicological sciences : an official journal of the Society of Toxicology.

Chemical‐induced asthma and the role of clinical, toxicological, exposure and epidemiological research in regulatory and hazard characterization approaches

J. Bernstein, D. Basketter, A. Maier, 2017, Regulatory toxicology and pharmacology : RTP.

Acute irritant reactivity to sodium lauryl sulfate in atopics and non‐atopics

D. Basketter, J. Miettinen, A. Lahti, 1998, Contact dermatitis.

Visual assessment of human skin irritation: a sensitive and reproducible tool

D. Basketter, F. Reynolds, M. Rowson, 1997, Contact dermatitis.

Skin irritation testing in man for hazard assessment — evaluation of four patch systems

James T. Cuthbert, D. Basketter, L. Neilson, 1995, Human & experimental toxicology.

A study of the relationship between susceptibility to skin stinging and skin irritation

D. Basketter, H. Griffiths, 1993, Contact dermatitis.

Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data

Manfred Liebsch, David Basketter, Helena Kandárová, 2010, Contact dermatitis.

Fragrances Categorized According to Relative Human Skin Sensitization Potency

Anne Marie Api, David A. Basketter, D. Basketter, 2017, Dermatitis.

Chemical allergens--what are the issues?

D. Basketter, I. Kimber, R. Dearman, 2010, Toxicology.

Structure activity relationships in skin sensitization using the murine local lymph node assay.

I Kimber, D A Basketter, J Ashby, 1995, Toxicology.

Pathology considerations for, and subsequent risk assessment of, chemicals identified as immunosuppressive in routine toxicology.

D. Basketter, I. Kimber, D. A. Stringer, 1995, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Updating the skin sensitization in vitro data assessment paradigm in 2009

Ian Kimber, D. Basketter, I. Kimber, 2009, Journal of applied toxicology : JAT.

Nonanimal alternatives for skin sensitization: a step forward?

David A Basketter, D. Basketter, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

An evaluation of selected global (Q)SARs/expert systems for the prediction of skin sensitisation potential

G Patlewicz, I Kimber, A O Aptula, 2007, SAR and QSAR in environmental research.

The Local Lymph Node Assay: Current Position in the Regulatory Classification of Skin Sensitizing Chemicals

G Frank Gerberick, Ian Kimber, David A Basketter, 2007, Cutaneous and ocular toxicology.

A future approach to measuring relative skin sensitising potency: a proposal

Carl Westmoreland, Ian Kimber, David A Basketter, 2006, Journal of applied toxicology : JAT.

The local lymph node assay and skin sensitization: a cut‐down screen to reduce animal requirements?

Petra S Kern, G Frank Gerberick, Ian Kimber, 2006, Contact dermatitis.

Evaluation of the skin sensitizing potency of chemicals by using the existing methods and considerations of relevance for elicitation

David A. Basketter, Klaus E. Andersen, Carola Liden, 2005, Contact dermatitis.

Evaluation of a human patch test for the identification and classification of skin irritation potential

D A Basketter, D. Basketter, E Whittle, 1996, Contact dermatitis.

An alternative strategy to the use of guinea pigs for the identification of skin sensitization hazard.

D A Basketter, M D Barratt, M Chamberlain, 1995, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

A two-center study of the development of acute irritation responses to fatty acids.

D. Basketter, M. Robinson, E. Whittle, 1999, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Interlaboratory evaluation of a human patch test for the identification of skin irritation potential/hazard.

D A Basketter, M K Robinson, K. Wilhelm, 1997, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Variation in response of human skin to irritant challenge

D. Basketter, R. Rycroft, D. A. Basketter, 1996, Contact dermatitis.

Differential cytokine production following chronic exposure of mice to chemical respiratory and contact allergens.

D. Basketter, I. Kimber, R. Dearman, 1995, Immunology.

The identification of chemicals with sensitizing or immunosuppressive properties in routine toxicology.

I Kimber, D A Basketter, D. Basketter, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Toll‐like receptor ligand activation of murine bone marrow‐derived dendritic cells

Gavin Maxwell, Ian Kimber, D. Basketter, 2009, Immunology.

Skin Sensitisation and Epidermal Disposition: The Relevance of Epidermal Disposition for Sensitisation Hazard Identification and Risk Assessment

Silvia Casati, Thomas Hartung, David Basketter, 2007, Alternatives to laboratory animals : ATLA.

An interlaboratory evaluation of the Buehler test for the identification and classification of skin sensitizers

G F Gerberick, D A Basketter, D. Basketter, 1996, Contact dermatitis.

Allergic Sensitization to Nickel and Implanted Metal Devices: A Perspective

D. Basketter, I. Kimber, 2021, Dermatitis : contact, atopic, occupational, drug.

Identification and classification of skin sensitizers: identifying false positives and false negatives

John McFadden, Peter Evans, Klaus E Andersen, 2006, Contact dermatitis.

Competitive inhibition of hexose transfer in human erythrocytes by Cytochalasin B [proceedings].

D. Basketter, W. F. Widdas, 1977, The Journal of physiology.

Occupational Exposure Limits for Enzymes: Practical Considerations

D. Basketter, 2021, International Journal of Pulmonary & Respiratory Sciences.

Evidence-Informed Occupational Exposure Limits for Enzymes.

D. Basketter, Merete Simonsen, P. Fox, 2019, Annals of work exposures and health.

Defining occupational and consumer exposure limits for enzyme protein respiratory allergens under REACH.

D. Basketter, C. Rodriguez, K. Maurer, 2010, Toxicology.

Experience with a mouse intranasal test for the predictive identification of respiratory sensitization potential of proteins.

D. Basketter, L. Blaikie, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Strain variation in the IgG1 antibody response to proteins administered intranasally in the mouse.

D. Basketter, L. Blaikie, 1999, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Managing the Risk of Occupational Allergy in the Enzyme Detergent Industry

D. Basketter, R. Bookstaff, F. Kruszewski, 2013, Journal of occupational and environmental hygiene.

Categorisation of protein respiratory allergens: the case of Subtilisin.

D. Basketter, I. Kimber, 2014, Regulatory toxicology and pharmacology : RTP.

The toxicology and immunology of detergent enzymes

D. Basketter, F. Kruszewski, K. Sarlo, 2012, Journal of immunotoxicology.

Enzymes in cleaning products: an overview of toxicological properties and risk assessment/management.

D. Basketter, C. Rodriguez, C. Kluin, 2012, Regulatory toxicology and pharmacology : RTP.

Industrial Enzymes

D. Basketter, M. Raulf, 2019, Kanerva’s Occupational Dermatology.

Atopic dermatitis and allergic reactions to individual fragrance chemicals

D. Buckley, D. Basketter, J. Mcfadden, 2009, Allergy.

Allergic contact dermatitis: epidemiology, molecular mechanisms, in vitro methods and regulatory aspects

A. M. Api, H. Maibach, A. Schnuch, 2011, Cellular and Molecular Life Sciences.

Risk management of skin sensitisers: A commentary.

D. Basketter, 2023, Regulatory toxicology and pharmacology : RTP.

Applying non-animal strategies for assessing skin sensitisation report from an EPAA/cefic-LRI/IFRA Europe cross sector workshop, ECHA helsinki, February 7th and 8th 2019.

Silvia Casati, Janine Ezendam, David Basketter, 2019, Regulatory toxicology and pharmacology : RTP.

Skin sensitization

I Kimber, D A Basketter, D. Basketter, 2015, Human & experimental toxicology.

Diagnostic patch testing—does it have a wider relevance?

D. Basketter, I. White, 2012, Contact dermatitis.

Nothing is perfect, not even the local lymph node assay: a commentary and the implications for REACH

Frank Gerberick, Amanda Cockshott, Ian Kimber, 2009, Contact dermatitis.

Local lymph node assay: validation assessment for regulatory purposes.

I Kimber, G F Gerberick, R J Dearman, 2000, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

Allergic contact dermatitis: is the reactive chemistry of skin sensitizers the whole story?

D. Basketter, I. Kimber, 2013, Contact dermatitis.

Synergistic effects of chemical insult and toll-like receptor ligands on dendritic cell activation.

D. Basketter, I. Kimber, R. Dearman, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Fragrance inhalation and adverse health effects: The question of causation

D. Basketter, I. Kimber, J. Huggard, 2019, Regulatory toxicology and pharmacology : RTP.

Skin sensitization: strategies for the assessment and management of risk

D A Basketter, D. Basketter, 2008, The British journal of dermatology.

Contact allergy: the local lymph node assay for the prediction of hazard and risk

D A Basketter, G. Patlewicz, D. Basketter, 2003, Clinical and experimental dermatology.

Identification and Assessment in Relation to the Material Safety Data Sheets

D. A. Basketter, L. Kanerva, D. Basketter, 2000 .

Skin irritation potential of mixed surfactant systems.

M. Barratt, D. Basketter, P. Revell, 1998, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The complex problem of sensitive skin

D. Basketter, J. Holmes, M. Rowson, 2005, Contact dermatitis.

In vitro approaches to the assessment of skin irritation and phototoxicity of topically applied materials

João Barroso, Chantra Eskes, David A. Basketter, 2007 .

Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity

D. Basketter, I. Jowsey, S. Knight, 2008, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Analysis of cytokine mRNA expression following repeated exposure of mice to chemical contact and respiratory allergens

D. Basketter, I. Kimber, G. Gerberick, 1998, Journal of applied toxicology : JAT.

Influence of topical exposure to chemical allergens on murine Langerhans cells. Comparison of 2,4-dinitrochlorobenzene with trimellitic anhydride.

S. Gould, D. Basketter, I. Kimber, 1992, Journal of clinical & laboratory immunology.

High frequency of simultaneous sensitivity to Disperse Orange 3 in patients with positive patch tests to para‐phenylenediamine

D. Basketter, R. Rycroft, I. White, 2003, Contact dermatitis.

The skin corrosivity test in vitro. Results of an inter-laboratory trial.

D A Basketter, J. C. McCall, D J Esdaile, 1992, Toxicology in vitro : an international journal published in association with BIBRA.

Mass spectrometric identification of covalent adducts of the skin allergen 2,4-dinitro-1-chlorobenzene and model skin proteins.

D. Basketter, A. Dell, H. Morris, 2008, Toxicology in vitro : an international journal published in association with BIBRA.

Chemical reactivity measurement and the predicitve identification of skin sensitisers. The report and recommendations of ECVAM Workshop 64.

Silvia Casati, David Basketter, Petra Kern, 2008, Alternatives to laboratory animals : ATLA.

Effect of glutathione on the covalent binding of the 13C-labeled skin sensitizer 5-chloro-2-methylisothiazol-3-one to human serum albumin: identification of adducts by nuclear magnetic resonance, matrix-assisted laser desorption/ionization mass spectrometry, and nanoelectrospray tandem mass spectrom

D. Basketter, A. Dell, H. Morris, 2004, Chemical Research in Toxicology.

Estimation of relative skin sensitizing potency using the local lymph node assay: a comparison of formaldehyde with glutaraldehyde.

D. Basketter, P. Evans, I. Kimber, 1998, American journal of contact dermatitis : official journal of the American Contact Dermatitis Society.

The Mouse IgE Test for the Identification of Potential Chemical Respiratory Allergens: Considerations of Stability and Controls

D. Basketter, I. Kimber, R. Dearman, 1996, Journal of applied toxicology : JAT.

An expert system rulebase for identifying contact allergens.

D A Basketter, M D Barratt, J J Langowski, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Inducible interleukin-4-secreting cells provoked in mice during chemical sensitization.

D. Basketter, I. Kimber, R. Dearman, 1994, Immunology.

Skin corrosivity potential of fatty acids: In vitro rat and human skin testing and QSAR studies.

M. Barratt, D. Basketter, M. Chamberlain, 1996, Toxicology in vitro : an international journal published in association with BIBRA.

Specificity of the local lymph node assay (LLNA) for skin sensitisation.

D. Basketter, I. Kimber, D. Roberts, 2023, Regulatory toxicology and pharmacology : RTP.

Comment on "Reduced specificity for the local lymph node assay for lipophilic chemicals: Implications for the validation of new approach methods for skin sensitization" (Natsch et al., 2023).

D. Basketter, D. Roberts, 2023, Regulatory toxicology and pharmacology : RTP.

Local lymph node assay - validation, conduct and use in practice.

R J Fielder, I Kimber, G F Gerberick, 2002, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Further evaluation of quantitative structure–activity relationship models for the prediction of the skin sensitization potency of selected fragrance allergens

G. Patlewicz, D. Roberts, D. Basketter, 2004, Contact dermatitis.

Para‐phenylendiamine (PPD) 1% pet. is an important allergen in the standard series

D. Basketter, M. Wilkinson, T. Diepgen, 2005, Contact Dermatitis.

Active sensitization to para‐phenylenediamine and its relevance: a 10‐year review

D. Basketter, R. Rycroft, J. Mcfadden, 2004, Contact Dermatitis.

Hair dye sensitivity testing: a critical commentary

D. Basketter, D. Orton, 2012, Contact dermatitis.

Experience with local lymph node assay performance standards using standard radioactivity and nonradioactive cell count measurements

Robert Landsiedel, David Basketter, D. Basketter, 2012, Journal of applied toxicology : JAT.

Assessing the severity of allergic reactions: a regulatory dilemma

D. Basketter, I. Kimber, J. McFadden, 2012, Contact dermatitis.

Experience with local lymph node assay performance standards using standard radioactivity and non-radioactive cell count measurements

Robert Landsiedel, Susanne N. Kolle, David A. Basketter, 2011 .

Information derived from sensitization test methods: test sensitivity, false positives and false negatives

Ian Kimber, David A Basketter, D. Basketter, 2007, Contact dermatitis.

Olive oil: suitability for use as a vehicle in the local lymph node assay

D. Basketter, I. Kimber, 1996, Contact dermatitis.

Sulphanilic acid: divergent results in the guinea pig maximization test and the local lymph node assay

I. Kimber, D. Basketter, I. Kimber, 1992, Contact dermatitis.

The Value of Animal Assays and the Quenching Phenomenon

D. Basketter, 1998 .

Performance standards and alternative assays: practical insights from skin sensitization.

Silvia Casati, Judy Strickland, Robert Landsiedel, 2013, Regulatory toxicology and pharmacology : RTP.

Studies of chemical selectivity of hapten, reactivity, and skin sensitization potency. 3. Synthesis and studies on the reactivity toward model nucleophiles of the 13C-labeled skin sensitizers, 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI).

Jean-Pierre Lepoittevin, David Basketter, Camilla Pease, 2003, Chemical research in toxicology.

Covalent binding of the 13C-labeled skin sensitizers 5-chloro-2-methylisothiazol-3-one (MCI) and 2-methylisothiazol-3-one (MI) to a model peptide and glutathione.

D. Basketter, J. Lepoittevin, C. Pease, 2004, Bioorganic & medicinal chemistry letters.

Influence of vitamin C on the elicitation of allergic contact dermatitis to p‐phenylenediamine

D. Basketter, I. White, J. McFadden, 2016, Contact dermatitis.

Investigation of the prohapten concept Cross reactions betwen 1,4‐substituted benzene derivatives in the guinea pig

D. Basketter, B. F. J. Gooodwin, 1988, Contact dermatitis.

Pre-testing in hair dye users: an assessment of the Colourstart system.

D. Basketter, J. English, 2009, European journal of dermatology : EJD.

Cutaneous reactivity of the hands in nickel‐sensitive patients with hand eczema

D. Basketter, S. Powell, C. Banfield, 1998, Contact Dermatitis.

The fragrance hand immersion study – an experimental model simulating real‐life exposure for allergic contact dermatitis on the hands

D. Basketter, M. Bruze, S. Heydorn, 2003, Contact dermatitis.

Labelling of skin sensitizers: the new European Dangerous Preparations Directive

D. Basketter, G. Gerberick, M. Robinson, 2001, Contact dermatitis.

Characterization of skin sensitizing chemicals: A lesson learnt from nickel allergy

Ian Kimber, David A Basketter, D. Basketter, 2011, Journal of immunotoxicology.

Optimised testing strategies for skin sensitization--the LLNA and beyond.

David Basketter, Bruno Hubesch, Irene Manou, 2012, Regulatory toxicology and pharmacology : RTP.

Evidence That Two Alkyl Ester Quaternary Ammonium Compounds Lack Substantial Human Skin‐Sensitizing Potential

David A Basketter, Ian R Jowsey, D. Basketter, 2007, Dermatitis : contact, atopic, occupational, drug.

Review of skin irritation/corrosion Hazards on the basis of human data: A regulatory perspective

D. Basketter, D. Jírová, H. Kanďárová, 2012, Interdisciplinary toxicology.

Skin sensitization, false positives and false negatives: experience with guinea pig assays

Ian Kimber, David A Basketter, D. Basketter, 2010, Journal of applied toxicology : JAT.

The human repeated insult patch test in the 21st century: A commentary

David A Basketter, D. Basketter, 2009, Cutaneous and ocular toxicology.

The impact of vehicle on the relative potency of skin-sensitizing chemicals in the local lymph node assay

Bob Safford, D. Basketter, I. Jowsey, 2008, Cutaneous and ocular toxicology.

The local lymph node assay in practice: a current regulatory perspective

I Kimber, G F Gerberick, R J Dearman, 2006, Human & experimental toxicology.

Measurement of allergenic potency using the local lymph node assay.

I Kimber, G F Gerberick, D A Basketter, 2001, Trends in pharmacological sciences.

Failure of vehicle to influence local lymph node assay response to benzocaine.

I Kimber, R J Dearman, D A Basketter, 2000, Contact dermatitis.

A quantitative structure-activity relationship (QSAR) investigation of a Draize eye irritation database.

D A Basketter, M. Cronin, D. Basketter, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Frequency of allergic contact dermatitis to isoeugenol is increasing: a review of 3636 patients tested from 2001 to 2005

D. Buckley, D. Basketter, J. Mcfadden, 2007, The British journal of dermatology.

The local lymph node assay: Results of a final inter‐laboratory validation under field conditions

I. Kimber, D. Basketter, I. Kimber, 1992, Journal of applied toxicology : JAT.

Multivariate QSAR analysis of a skin sensitization database.

D A Basketter, M. Cronin, M. Cronin, 1994, SAR and QSAR in environmental research.

Interlaboratory Evaluation of the Local Lymph Node Assay with 25 Chemicals and Comparison with Guinea Pig Test Data

D. Basketter, P. Botham, I. Kimber, 1991 .

Local Lymph Node Data for the Evaluation of Skin Sensitization Alternatives: A Second Compilation

Aynur Aptula, Ian Kimber, David A. Basketter, 2010, Dermatitis : contact, atopic, occupational, drug.

Reproducible prediction of contact allergenic potency using the local lymph node assay

D. Basketter, David A. Basketter, P. Cadby, 2004, Contact dermatitis.

Skin sensitisation testing in practice: Applying a stacking meta model to cosmetic ingredients.

Joan Eilstein, Hicham Noçairi, David Basketter, 2020, Toxicology in vitro : an international journal published in association with BIBRA.

Identification of Skin Allergens by In Vivo Assay

D. Basketter, 2019, Kanerva’s Occupational Dermatology.

Alternatives for skin sensitisation: Hazard identification and potency categorisation: Report from an EPAA/CEFIC LRI/Cosmetics Europe cross sector workshop, ECHA Helsinki, April 23rd and 24th 2015.

Andrew Worth, Silvia Casati, Robert Landsiedel, 2015, Regulatory toxicology and pharmacology : RTP.

Correlation between experimental human and murine skin sensitization induction thresholds

David Basketter, Anne Marie Api, Jon Lalko, 2015, Cutaneous and ocular toxicology.

Skin sensitisation--moving forward with non-animal testing strategies for regulatory purposes in the EU.

Silvia Casati, Robert Landsiedel, David Basketter, 2013, Regulatory toxicology and pharmacology : RTP.

Skin Immunology and Sensitisation

D. Basketter, 2008 .

A chemical dataset for evaluation of alternative approaches to skin‐sensitization testing

Ian Kimber, G. Patlewicz, D. Basketter, 2004, Contact dermatitis.

The local lymph node assay: status of validation.

D. Basketter, M. Chamberlain, 1996, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

Hydrolyzed protein shampoo additives are not a common contact allergen.

S. Wakelin, D. Basketter, R. Rycroft, 2000, Contact dermatitis.

Simultaneous sensitivity to fragrances

D. Buckley, D. Basketter, R. Rycroft, 2006, The British journal of dermatology.

Reactivity assays, substances, samples and in vitro alternatives: why should we care?

D. Basketter, D. Roberts, 2009, Contact dermatitis.

Computer-aided knowledge generation for understanding skin sensitization mechanisms: the TOPS-MODE approach.

Ernesto Estrada, Grace Patlewicz, Mark Chamberlain, 2003, Chemical research in toxicology.

Further evaluation of the quantitative structure‐activity relationship for skin‐sensitizing alkyl transfer agents

D W Roberts, D A Basketter, D. Roberts, 1997, Contact dermatitis.

Structure-activity relationships for contact allergenic potential of gamma,gamma-dimethyl-gamma-butyrolactone derivatives. 1. Synthesis and electrophilic reactivity studies of alpha-(omega-substituted-alkyl)-gamma,gamma-dimethyl-gamma-butyrolacton es and correlation of skin sensitization potential a

D. Roberts, D. Basketter, C. Benezra, 1994, Chemical research in toxicology.

Structure-activity relationships for contact allergenic potential of gamma,gamma-dimethyl-gamma-butyrolactone derivatives. 2. Quantitative structure-skin sensitization relationships for alpha-substituted-alpha-methyl-gamma,gamma-dimethyl-gamma-butyrolactone s.

D W Roberts, D A Basketter, C Benezra, 1994, Chemical research in toxicology.

Structure-activity relationships in the murine local lymph node assay for skin sensitization: alpha,beta-diketones.

D W Roberts, D A Basketter, D. Roberts, 1999, Contact dermatitis.

Proteolytic activity accelerates the TH17/TH22 recall response to an epicutaneous protein allergen-induced TH2 response

D. Basketter, H. Sakaguchi, Yi-Ting Lai, 2022, Journal of immunotoxicology.

42 Industrial Enzymes

D. Basketter, 2012 .

Extrapolating Local Lymph Node Assay EC3 Values To Estimate Relative Sensitizing Potency

Ian Kimber, David A. Basketter, Petra S. Kern, 2007, Cutaneous and ocular toxicology.

Letter to ESCD members

D. Basketter, 2002 .

Human volunteer studies; a consumer products company view

D A Basketter, D. Basketter, V Scailteur, 1999, Human & experimental toxicology.

A comparison of statistical approaches to the derivation of EC3 values from local lymph node assay dose responses

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

Cytokine endpoints for the local lymph node assay: consideration of interferon‐γ and interleukin 12

D. Basketter, I. Kimber, R. Dearman, 1999, Journal of applied toxicology : JAT.

Possible allergy to complex titanium salt.

D. Basketter, E. Whittle, B. Monk, 2000, Contact dermatitis.

Strategic hierarchical approaches to acute toxicity testing.

D A Basketter, D. Basketter, 1994, Toxicology in vitro : an international journal published in association with BIBRA.

Plant extracts, polymers and new approach methods: Practical experience with skin sensitization assessment.

D. Basketter, R. Landsiedel, S. Kolle, 2023, Regulatory toxicology and pharmacology : RTP.

Further experience with the local lymph node assay using standard radioactive and nonradioactive cell count measurements

Robert Landsiedel, David Basketter, D. Basketter, 2012, Journal of applied toxicology : JAT.

Selectivity of IgE responses, mast cell sensitization, and cytokine expression in the immune response of Brown Norway rats to chemical allergens.

D. Basketter, I. Kimber, R. Dearman, 1996, Cellular immunology.

Dissemination Strategies: How do they Influence the Uptake of New three Rs Methods across Laboratories and Other Boundaries?

J. Linge, D. Basketter, H. Spielmann, 2008 .

Dissemination strategies: how do they influence the uptake of the new Three Rs methods across laboratories and other boundaries? A report of a workshop held by the European Partnership for Alternative Approaches to Animal Testing (EPAA) Working Group 3.

J. Linge, D. Basketter, H. Spielmann, 2008, Alternatives to laboratory animals : ATLA.

In vitro skin corrosivity test using human skin.

D. Basketter, E. Whittle, 1994, Toxicology in Vitro.

Identification of irritation and corrosion hazards to skin: an alternative strategy to animal testing.

D. Basketter, M. Chamberlain, E. Whittle, 1994, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.

The in vitro skin corrosivity test. Development of method using human skin.

D. Basketter, E. Whittle, 1993, Toxicology in vitro : an international journal published in association with BIBRA.

The in vitro skin corrosivity test. Comparison of in vitro human skin with in vivo data.

D. Basketter, E. Whittle, 1993, Toxicology in vitro : an international journal published in association with BIBRA.

Mutagens and Sensitizers—An Unequal Relationship?

D. Basketter, A. Wolfreys, 2005 .

The Local Lymph Node Assay

G. Frank Gerberick, Ian Kimber, David A. Basketter, 2017 .

Management of an Integrated Project (Sens-it-iv) to Develop In Vitro Tests to Assess Sensitisation

Silvia Casati, David Basketter, Irene Manou, 2007, Alternatives to laboratory animals : ATLA.

Application of a weight of evidence approach to assessing discordant sensitisation datasets: implications for REACH.

Reinhard Kreiling, Nicholas Ball, David Basketter, 2009, Regulatory toxicology and pharmacology : RTP.

The suitability of hexyl cinnamic aldehyde as a calibrant for the murine local lymph node assay

Ian Kimber, D. Basketter, I. Kimber, 2001, Contact dermatitis.

Reciprocal effects of interleukin‐4 and interferon‐γ on immunoglobulin E‐mediated mast cell degranulation: a role for nitric oxide but not peroxynitrite or cyclic guanosine monophosphate

Kimber, Dearman, D. Basketter, 1999, Immunology.

Integrated Testing Strategies (ITS) for safety assessment.

A. M. Api, L. Smirnova, J. Pitchford, 2015, ALTEX.

Dose metrics in the acquisition of skin sensitization: thresholds and importance of dose per unit area.

A. M. Api, D. Basketter, I. Kimber, 2008, Regulatory toxicology and pharmacology : RTP.

Skin sensitization quantitative risk assessment: A review of underlying assumptions.

D. Basketter, B. Safford, 2016, Regulatory toxicology and pharmacology : RTP.

An arm immersion model of compromised skin

D. Basketter, C. Allenby, A. Dickens, 1993, Contact dermatitis.

Modulation of EGF Receptors during Epidermal Hyperplasia

D. Basketter, 1986 .

Optimised testing strategies for skin sensitization--the LLNA and beyond.

D. Basketter, B. Hubesch, A. Mehling, 2012, Regulatory toxicology and pharmacology : RTP.

Selection of Chemicals for the Development and Evaluation of In Vitro Methods for Skin Sensitisation Testing

Silvia Casati, Gavin Maxwell, Costanza Rovida, 2009 .

Benzalkonium chloride neutralizes the irritant effect of sodium dodecyl sulfate

D. Basketter, J. Mcfadden, E. Whittle, 2000, Contact dermatitis.

Dendritic cell research projects.

D. Basketter, I. Kimber, F. Gerberick, 2006 .