J. Um

发表

A bitter herbal medicine Gentiana scabra root extract stimulates glucagon-like peptide-1 secretion and regulates blood glucose in db/db mouse.

Hyo-Weon Suh, Ki-Beom Lee, Ki-Suk Kim, 2015, Journal of ethnopharmacology.

Arctigenin Inhibits Adipogenesis by Inducing AMPK Activation and Reduces Weight Gain in High‐Fat Diet‐Induced Obese Mice

R. Park, J. Um, Yo-Han Han, 2016, Journal of cellular biochemistry.

Green tea seed oil reduces weight gain in C57BL/6J mice and influences adipocyte differentiation by suppressing peroxisome proliferator-activated receptor-γ

J. Um, Su-jin Kim, Seung-Heon Hong, 2008, Pflügers Archiv - European Journal of Physiology.

Novel approach of molecular genetic understanding of iridology: relationship between iris constitution and angiotensin converting enzyme gene polymorphism.

J. Um, Seung-Heon Hong, Hyung-Ryong Kim, 2005, The American journal of Chinese medicine.

Anti-cancer effect of Eriocaulon sieboldianum through the activation of caspase-3 in human leukemia cell line, HL-60 cells

J. Um, H. M. Kim, Su-jin Kim, 2009 .

Anti-inflammatory activity of Schizonepeta tenuifolia through the inhibition of MAPK phosphorylation in mouse peritoneal macrophages.

Dong-Hyun Kim, J. Um, Su-jin Kim, 2008, The American journal of Chinese medicine.

Fructus Ligustrum lucidi inhibits inflammatory mediator release through inhibition of nuclear factor‐κB in mouse peritoneal macrophages

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2007, The Journal of pharmacy and pharmacology.

The Antiinflammatory Mechanism of Igongsan in Mouse Peritoneal Macrophages via Suppression of NF‐κB/Caspase‐1 Activation

J. Um, Jong Hyun Lee, Sung-Hoon Kim, 2014, Phytotherapy research : PTR.

Candidate genes of cerebral infarction and traditional classification in Koreans with cerebral infarction

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2005, The International journal of neuroscience.

Association between iris constitution and apolipoprotein e gene polymorphism in hypertensives.

J. Um, Sung-Hoon Kim, Seung-Heon Hong, 2004, Journal of alternative and complementary medicine.

Polymorphism of angiotensin-converting enzyme, angiotensinogen, and apolipoprotein E genes in Korean patients with cerebral infarction

J. Um, Hyung‐Min Kim, Kwang-Ho Cho, 2003, Journal of Molecular Neuroscience.

Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway

J. Um, Jinbong Park, Hye-Lin Kim, 2018, European journal of pharmacology.

LPS-INDUCED INFLAMMATORY CYTOKINE PRODUCTION WAS INHIBITED BY HYUNGBANGJIHWANGTANG THROUGH BLOCKADE OF NF-κB IN PERIPHERAL BLOOD MONONUCLEAR CELLS

J. Um, Seung-Heon Hong, P. Moon, 2007, The International journal of neuroscience.

YULDA-HANSO-TANG ATTENUATES THE ENDOTOXIN-INDUCED INFLAMMATORY CYTOKINE PRODUCTION IN PERIPHERAL BLOOD MONONUCLEAR CELLS

J. Um, Su-jin Kim, Seung-Heon Hong, 2007, The International journal of neuroscience.

Functional Polymorphism of IL-1 Alpha and Its Potential Role in Obesity in Humans and Mice

J. Um, Hye-Lin Kim, Su-jin Kim, 2011, PloS one.

Inhibitory effects of Saururus chinensis (LOUR.) BAILL on the development of atopic dermatitis-like skin lesions in NC/Nga mice.

J. Um, H. M. Kim, B. Min, 2008, Biological & pharmaceutical bulletin.

Arctigenin Inhibits Lung Metastasis of Colorectal Cancer by Regulating Cell Viability and Metastatic Phenotypes

J. Um, Yo-Han Han, Ji-Ye Kee, 2016, Molecules.

Mori Folium regulates DSS-induced ulcerative colitis in mice and cytokine production in mast cells

J. Um, Ji-Ye Kee, Dae-Seung Kim, 2012, Oriental Pharmacy and Experimental Medicine.

Vanillic Acid Improves Comorbidity of Cancer and Obesity through STAT3 Regulation in High-Fat-Diet-Induced Obese and B16BL6 Melanoma-Injected Mice

J. Um, Jinbong Park, Yunu Jung, 2020, Biomolecules.

Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-κB and caspase-1 activation.

J. Um, Sung-Hoon Kim, Dae-Seung Kim, 2015, Molecular medicine reports.

Molecular authentication of Panax ginseng species by RAPD analysis and PCR-RFLP.

J. Um, H. Kim, H. Na, 2001, Biological & pharmaceutical bulletin.

Ginsenoside Rb1 Induces Beta 3 Adrenergic Receptor–Dependent Lipolysis and Thermogenesis in 3T3-L1 Adipocytes and db/db Mice

J. Um, Jinbong Park, Seona Lim, 2019, Front. Pharmacol..

Cynanchum atratum inhibits the development of atopic dermatitis in 2,4-dinitrochlorobenzene-induced mice.

K. Ahn, J. Um, Seok-Geun Lee, 2017, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Antiapoptotic mechanism of cannabinoid receptor 2 agonist on cisplatin‐induced apoptosis in the HEI‐OC1 auditory cell line

J. Um, Sejin Jeong, Su-jin Kim, 2007, Journal of neuroscience research.

Mild NO preconditioning protects H9c2 cells against NO-induced apoptosis through activation of PI3K/Akt and PKA-dependent pathways

J. Um, Sang-Seob Lee, H. Kwak, 2019, Molecular & Cellular Toxicology.

PEX13 is required for thermogenesis of white adipose tissue in cold-induced mice.

K. Ahn, J. Um, Jinbong Park, 2021, Biochimica et biophysica acta. Molecular and cell biology of lipids.

Fruit of Hovenia dulcis Thunb. induces non-shivering thermogenesis through mitochondrial biogenesis and activation by SIRT1 in high fat diet-fed obese mice and primary cultured brown adipocytes.

K. Ahn, J. Um, Jinbong Park, 2020, Journal of agricultural and food chemistry.

Gamiwalbitang, composed of four herbs, controls body weight increase and lipid level elevation induced by a high-fat diet in mice

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2010, Immunopharmacology and immunotoxicology.

Aqueous extracts of Anemarrhena asphodeloides stimulate glucagon-like pepetide-1 secretion in enteroendocrine NCI-H716 cells

Eun-Young Kim, Ki-Suk Kim, Min-Hee Shin, 2013, BioChip Journal.

Anti-neoplastic Effect of Ginkgolide C through Modulating c-Met Phosphorylation in Hepatocellular Carcinoma Cells

K. Ahn, J. Um, S. Baek, 2020, International journal of molecular sciences.

Evodiamine Mitigates Cellular Growth and Promotes Apoptosis by Targeting the c-Met Pathway in Prostate Cancer Cells

K. Ahn, J. Um, A. Chinnathambi, 2020, Molecules.

Arctii Fructus Inhibits Colorectal Cancer Cell Proliferation and MMPs Mediated Invasion via AMPK.

J. Um, Yo-Han Han, Ji-Ye Kee, 2017, The American journal of Chinese medicine.

β-Lapachone Inhibits Lung Metastasis of Colorectal Cancer by Inducing Apoptosis of CT26 Cells

K. Ahn, J. Um, Yo-Han Han, 2016, Integrative cancer therapies.

Molecular Discrimination of Medicinal Astragali Radix by RAPD Analysis

J. Um, Cheorl-Ho Kim, Hyung‐Min Kim, 2004, Immunopharmacology and immunotoxicology.

Polymorphism of the angiotensin-converting enzyme gene in patients with cerebral infarction in koreans

J. Um, Hyung‐Min Kim, N. An, 2001, Journal of Molecular Neuroscience.

Proinflammatory cytokine IL-1 β polymorphisms in sudden sensorineural hearing loss

C. Jang, K. Ahn, J. Um, 2013, Immunopharmacology and immunotoxicology.

Steroid Combination Therapy and Detoxification Enzyme Gene Polymorphisms in Sudden Sensorineural Hearing Loss Patients

C. Jang, J. Um, Hye-Lin Kim, 2011, Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology.

Candidate Genes of Cerebrovascular Disease and Sudden Sensorineural Hearing Loss

C. Jang, J. Um, Su-jin Kim, 2010, Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis.

The effect of topically administered latanoprost on the cochlear blood flow and hearing.

C. Jang, J. Um, Pa-Chun Wang, 2013, International journal of pediatric otorhinolaryngology.

Lipid profile lowering effect of SoyproTM fermented with lactic acid bacteria isolated from Kimchi in high‐fat diet‐induced obese rats

J. Um, Su-jin Kim, Seung-Heon Hong, 2008, BioFactors.

Association of interleukin-18 gene polymorphism with body mass index in women

J. Um, Sung-Hoon Kim, Hye-Lin Kim, 2012, Reproductive Biology and Endocrinology.

Association of interleukin-1beta gene polymorphism with body mass index in women.

Hwan-Suck Chung, J. Um, Hyung‐Min Kim, 2004, Clinical chemistry.

Polymorphism of the tumor necrosis factor alpha gene and waist-hip ratio in obese Korean women.

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2004, Molecules and cells.

Gene polymorphisms in tumor necrosis factor locus and waist-hip ratio in obese Koreans.

J. Um, Hyung‐Min Kim, Jae-Hwang Park, 2003, Clinica chimica acta; international journal of clinical chemistry.

Original Article Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells

K. Ahn, J. Um, Seok-Geun Lee, 2015 .

Simvastatin in combination with bergamottin potentiates TNF-induced apoptosis through modulation of NF-κB signalling pathway in human chronic myelogenous leukaemia

K. Ahn, J. Um, Sung-moo Kim, 2016, Pharmaceutical biology.

Taeumjowi-tang, a Traditional Korean Sasang Remedy, Improves Obesity-Atopic Dermatitis Comorbidity by Regulating Hypoxia-Inducible Factor 1 Alpha

K. Ahn, J. Um, Jinbong Park, 2019, Front. Pharmacol..

Panax Ginseng inhibited HIF-1a activation and inflammatory cytokine in HMC-1 cells activated by phorbol myristate acetate and A23187

J. Um, H. M. Kim, Seung-Heon Hong, 2008 .

Hesperidin inhibits expression of hypoxia inducible factor-1 alpha and inflammatory cytokine production from mast cells

Ji‐Hyun Lee, J. Um, Su-jin Kim, 2007, Molecular and Cellular Biochemistry.

Activation of hypoxia-inducible factor-1 regulates human histidine decarboxylase expression

J. Um, P. Moon, J. J. Kim, 2009, Cellular and Molecular Life Sciences.

Effects of the water of yellow soil, Ji-Jang-Soo on cell viability and cytokines production in immune cells

J. Um, H. M. Kim, Seung-Heon Hong, 2006 .

Korean Red Ginseng improves atopic dermatitis-like skin lesions by suppressing expression of proinflammatory cytokines and chemokines in vivo and in vitro

K. Ahn, J. Um, Yo-Han Han, 2016, Journal of ginseng research.

Effects of Ixeris dentata water extract and caffeic acid on allergic inflammation in vivo and in vitro

J. Um, Sung-Hoon Kim, Yo-Han Han, 2015, BMC Complementary and Alternative Medicine.

Haeamtang induces apoptosis of colon cancer HT-29 cells through activation of caspase-3.

J. Um, Su-jin Kim, Seung-Heon Hong, 2007, The American journal of Chinese medicine.

Association of a multidrug resistance 1 gene polymorphism and colorectal cancer in the Korean population

J. Um, Yun-Kyung Kim, Hyun-Ju Kim, 2013, Oriental Pharmacy and Experimental Medicine.

β-Lapachone suppresses the lung metastasis of melanoma via the MAPK signaling pathway

R. Park, J. Um, Yo-Han Han, 2017, PloS one.

Generation of nitric oxide inhibits formation of superoxide in macrophages during activation.

C. Jun, J. Um, H. Kwak, 1994, Biochemistry and molecular biology international.

Antiproliferative effects of Dangyuja (Citrus grandis Osbeck) leaves through suppression of constitutive signal transducer and activator of transcription 3 activation in human prostate carcinoma DU145 cells.

Yun‐Cheol Na, K. Ahn, J. Um, 2012, Journal of medicinal food.

Expression of inducible nitric oxide synthase by Corydalis turtschaninovii on interferon-gamma stimulated macrophages.

Hwan-Suck Chung, J. Um, Su-jin Kim, 2009, Journal of ethnopharmacology.

Leonurus sibiricus induces nitric oxide and tumor necrosis factor-alpha in mouse peritoneal macrophages.

Ji‐Hyun Lee, J. Um, Jong-Hyun Lee, 2008, Canadian journal of physiology and pharmacology.

Induction of nitric oxide & tumour necrosis factor-alpha by Psoralea corylifolia.

J. Um, Sejin Jeong, Seung-Heon Hong, 2008, The Indian journal of medical research.

The effects of complex herbal medicine composed of Cornus fructus, Dioscoreae rhizoma, Aurantii fructus, and Mori folium in obese type-2 diabetes mice model

Ki-Suk Kim, Hea Jung Yang, Eun-Kyeong Choi, 2013, Oriental Pharmacy and Experimental Medicine.

TNF-alpha and TNF-beta gene polymorphisms in cerebral infarction.

J. Um, Hyung‐Min Kim, N. An, 2003, Journal of molecular neuroscience : MN.

Interleukin-1alpha polymorphism -889C/T related to obesity in Korean Taeumin women.

J. Um, Su-jin Kim, Seung-Heon Hong, 2008, The American journal of Chinese medicine.

Interleukin-1 Beta Gene Polymorphism and Traditional Constitution in Obese Women

J. Um, Seung-Heon Hong, Jeong‐Hoon Lee, 2008, The International journal of neuroscience.

INTERLEUKIN-1 RECEPTOR ANTAGONIST GENE POLYMORPHISM AND TRADITIONAL CLASSIFICATION IN OBESE WOMEN

J. Um, Yung-sun Song, Seung-Heon Hong, 2006, The International journal of neuroscience.

Polymorphism of interleukin-1 receptor antagonist gene and obesity.

J. Um, Hyung‐Min Kim, Kang-Min Lee, 2004, Clinica chimica acta; international journal of clinical chemistry.

Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IκB/NF-κB signal cascade in the human mast cell line HMC-1

J. Um, Seung-Heon Hong, Hyung-Ryong Kim, 2007 .

Ellagic acid induces beige remodeling of white adipose tissue by controlling mitochondrial dynamics and SIRT3

K. Ahn, J. Um, Jinbong Park, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Farnesol induces mitochondrial/peroxisomal biogenesis and thermogenesis by enhancing the AMPK signaling pathway in vivo and in vitro.

K. Ahn, J. Um, Jinbong Park, 2020, Pharmacological research.

Black Raspberry (Rubus coreanus Miquel) Promotes Browning of Preadipocytes and Inguinal White Adipose Tissue in Cold-Induced Mice

J. Um, Jinbong Park, S. Choe, 2019, Nutrients.

Farnesol Has an Anti-obesity Effect in High-Fat Diet-Induced Obese Mice and Induces the Development of Beige Adipocytes in Human Adipose Tissue Derived-Mesenchymal Stem Cells

R. Park, K. Ahn, J. Um, 2017, Front. Pharmacol..

Chrysophanic Acid Suppresses Adipogenesis and Induces Thermogenesis by Activating AMP-Activated Protein Kinase Alpha In vivo and In vitro

K. Ahn, J. Um, Jinbong Park, 2016, Front. Pharmacol..

Vanillic acid attenuates obesity via activation of the AMPK pathway and thermogenic factors in vivo and in vitro

K. Ahn, J. Um, Seok-Geun Lee, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The AMPK pathway mediates an anti-adipogenic effect of fruits of Hovenia dulcis Thunb.

J. Kim, J. Um, Jinbong Park, 2014, Food & function.

CYP1A1 and GSTM1/T1 Genetic Variation in Predicting Risk for Cerebral Infarction

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2007, Journal of Molecular Neuroscience.

Synergistic cooperation between phorbol ester and IFN-gamma for induction of nitric oxide synthesis in murine peritoneal macrophages.

S. Paik, C. Jun, J. Um, 1994, Journal of immunology.

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo

P. Fisher, K. Ahn, J. Um, 2018, Cell Death & Disease.

Rubi Fructus (Rubus coreanus) activates the expression of thermogenic genes in vivo and in vitro

R. Park, J. Um, Mi-Young Jeong, 2014, International Journal of Obesity.

β -Lapachone Regulates Obesity through Modulating Thermogenesis in Brown Adipose Tissue and Adipocytes: Role of AMPK Signaling Pathway.

J. Um, Jinbong Park, Mi-Young Jeong, 2019, The American journal of Chinese medicine.

Rubi Fructus (Rubus coreanus) Inhibits Differentiation to Adipocytes in 3T3-L1 Cells

R. Park, J. Um, Sung-Hoon Kim, 2013, Evidence-based complementary and alternative medicine : eCAM.

Veratri Nigri Rhizoma et Radix (Veratrum nigrum L.) and Its Constituent Jervine Prevent Adipogenesis via Activation of the LKB1-AMPKα-ACC Axis In Vivo and In Vitro

J. Um, Junhee Lee, Yo-Han Han, 2016, Evidence-based complementary and alternative medicine : eCAM.

A Novel Role of Bergamottin in Attenuating Cancer Associated Cachexia by Diverse Molecular Mechanisms

G. Sethi, K. Ahn, J. Um, 2021, Cancers.

Anti-inflammatory activities of Reynoutria elliptica through suppression of mitogen-activated protein kinases and nuclear factor-κB activation pathways

K. Ahn, J. Um, H. Jang, 2012, Immunopharmacology and immunotoxicology.

Phenolic-rich fraction from Rhus verniciflua Stokes (RVS) suppress inflammatory response via NF-kappaB and JNK pathway in lipopolysaccharide-induced RAW 264.7 macrophages.

J. Kim, J. Um, H. M. Kim, 2007, Journal of ethnopharmacology.

Vanillic acid attenuates testosterone-induced benign prostatic hyperplasia in rats and inhibits proliferation of prostatic epithelial cells

G. Sethi, K. Ahn, J. Um, 2017, Oncotarget.

Glutathione S-transferase gene polymorphism in Korean subjects with gastric and colorectal cancer

J. Um, Yun-Kyung Kim, Hyun-Ju Kim, 2012, Oriental Pharmacy and Experimental Medicine.

The Beneficial Effect of Vanillic Acid on Ulcerative Colitis

J. Um, Su-jin Kim, Seung-Heon Hong, 2010, Molecules.

The therapeutic effect of chelidonic acid on ulcerative colitis.

J. Um, Dae-Seung Kim, Yong-Deok Jeon, 2012, Biological & pharmaceutical bulletin.

Fruit of Gardenia jasminoides Induces Mitochondrial Activation and Non-Shivering Thermogenesis through Regulation of PPARγ

K. Ahn, J. Um, Jinbong Park, 2021, Antioxidants.

Effect of Pilopool on Forced Swimming Test in Mice

J. Um, Seung-Heon Hong, H. Koo, 2008, The International journal of neuroscience.

Beneficial effect of dietary Ephedra sinica on obesity and glucose intolerance in high-fat diet-fed mice.

J. Um, H. Jang, Byung-Cheol Lee, 2012, Experimental and therapeutic medicine.

Raphani Semen (Raphanus sativus L.) Ameliorates Alcoholic Fatty Liver Disease by Regulating De Novo Lipogenesis

J. Um, Jinbong Park, Taegon Kim, 2021, Nutrients.

Association of interleukin-1 alpha gene polymorphism with cerebral infarction.

J. Um, Hyung‐Min Kim, Kwang-Ho Cho, 2003, Brain research. Molecular brain research.

Induction of Apoptosis by KI0477959 through Activation of Caspase-3 in Human Leukemia Cell Line, HL-60 Cells

J. Um, Sejin Jeong, Seung-Heon Hong, 2008, The International journal of neuroscience.

Allyl isothiocyanate regulates caspase-1/receptor interacting protein-2 expression.

J. Um, Na‐Ra Han, Hyung‐Min Kim, 2011, International immunopharmacology.

Association between P478S polymorphism of the filaggrin gene & atopic dermatitis

J. Um, Sung-Hoon Kim, Hye-Lin Kim, 2013, The Indian journal of medical research.

The immunosuppressive effect of Buchang-tang through inhibition of mitogen-activated protein kinase and nuclear factor activation in MOLT-4 cells.

J. Um, Seung-Heon Hong, Hyung-Ryong Kim, 2005, Journal of ethnopharmacology.

Oldenlandia diffusa Ameliorates Dextran Sulphate Sodium-Induced Colitis Through Inhibition of NF-κB Activation.

J. Um, H. Jang, Hye-Lin Kim, 2011, The American journal of Chinese medicine.

The protective effect of Cassia obtusifolia on DSS-induced colitis.

J. Um, H. Jang, Dae-Seung Kim, 2011, The American journal of Chinese medicine.

The improving effects of Saengmaeksan on ulcerative colitis

J. Um, H. M. Kim, Dae-Seung Kim, 2010 .

Samsoeum inhibits systemic anaphylaxis and release of histamine, cytokine in vivo and in vitro

J. Um, H. M. Kim, Seung-Heon Hong, 2009 .

Ailanthus altissima swingle has anti-anaphylactic effect and inhibits inflammatory cytokine expression via suppression of nuclear factor-kappaB activation

J. Um, Sung-Hoon Kim, Su-jin Kim, 2009, In Vitro Cellular & Developmental Biology - Animal.

The anti-allergy and anti-inflammatory effect of Anemarrhenae Rhizoma in vivo and in vitro

J. Um, H. M. Kim, Su-jin Kim, 2007 .

Use of Electroacupuncture at ST36 to Inhibit Anaphylactic and Inflammatory Reaction in Mice

J. Um, Su-jin Kim, Seung-Heon Hong, 2007, Neuroimmunomodulation.

Anti-Inflammatory Effect of Dohongsamultang through Inhibition of Nuclear Factor-κB Activation in Peripheral Blood Mononuclear Cells of Patients with Cerebral Infarction

J. Um, Su-jin Kim, Seung-Heon Hong, 2007 .

Epigallocatechin-3-Gallate Inhibits Secretion of TNF-α, IL-6 and IL-8 through the Attenuation of ERK and NF-κB in HMC-1 Cells

J. Um, Seung-Heon Hong, Sang-Hyun Kim, 2006, International Archives of Allergy and Immunology.

The anti-inflammatory effect of gigukjiwhangwhangami through the inhibition of nuclear factor-κB activation in the peripheral blood mononuclear cells of patients with cerebral infarction

J. Um, Su-jin Kim, Seung-Heon Hong, 2006 .

The Effect of SHJKS on Cytokines Production and NF-κB Activation in the Peripheral Blood Mononuclear Cells of Patients with Cerebral Infarction

J. Um, Su-jin Kim, Seung-Heon Hong, 2006, Immunopharmacology and immunotoxicology.

INHIBITORY EFFECT OF YANGKYUK-SANHWA-TANG ON INFLAMMATORY CYTOKINE PRODUCTION IN PERIPHERAL BLOOD MONONUCLEAR CELLS FROM THE CEREBRAL INFARCTION PATIENTS

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2007, The International journal of neuroscience.

Aspects of gene polymorphisms in cerebral infarction: inflammatory cytokines

J. Um, H. M. Kim, H. Jeong, 2005, Cellular and Molecular Life Sciences CMLS.

Isoimperatorin down-regulates epithelial mesenchymal transition through modulating NF-κB signaling and CXCR4 expression in colorectal and hepatocellular carcinoma cells.

G. Sethi, K. Ahn, J. Um, 2022, Cellular signalling.

Agonists of proteinase‐activated receptor 2 induce TNF‐αsecretion from astrocytoma cells

J. Um, Mi‐Sun Kim, Young‐Mi Lee, 2002, Cell biochemistry and function.

Observations of Forsythia koreana methanol extract on mast cell-mediated allergic reactions in experimental models

Ji‐Hyun Lee, J. Um, Su-jin Kim, 2007, In Vitro Cellular & Developmental Biology - Animal.

Fangchinoline abrogates growth and survival of hepatocellular carcinoma by negative regulation of c‐met/HGF and its associated downstream signaling pathways

G. Sethi, K. Ahn, J. Um, 2022, Phytotherapy research : PTR.

Zileuton, a 5-Lipoxygenase Inhibitor, Exerts Anti-Angiogenic Effect by Inducing Apoptosis of HUVEC via BK Channel Activation

J. Um, Jinbong Park, Hyun-Joung Lim, 2019, Cells.

Relationship between iris constitution analysis and TNF-alpha gene polymorphism in hypertensives.

J. Um, Su-jin Kim, Seung-Heon Hong, 2007, The American journal of Chinese medicine.

Association between tumor necrosis factor-alpha gene polymorphism and Sasang constitution in cerebral infarction.

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2005, The American journal of Chinese medicine.

Tumor necrosis factor alpha gene polymorphism is associated with cerebral infarction.

J. Um, Hyung‐Min Kim, 2004, Brain research. Molecular brain research.

Frequencies of the tumor necrosis factor gene polymorphisms in the Korean population.

J. Um, Hyung‐Min Kim, 2004, Hereditas.

Interleukin-1 gene cluster polymorphisms in cerebral infarction.

J. Um, Hyung‐Min Kim, K. Moon, 2003, Cytokine.

The bark of Betula platyphylla var. japonica inhibits the development of atopic dermatitis-like skin lesions in NC/Nga mice.

J. Um, B. Min, H. Bae, 2008, Journal of ethnopharmacology.

The regulatory mechanism of β-eudesmol is through the suppression of caspase-1 activation in mast cell–mediated inflammatory response

J. Um, Su-jin Kim, Seung-Heon Hong, 2011, Immunopharmacology and immunotoxicology.

Screening of KMU-4, 6, 7 on inflammatory responses in IFN-γ and LPS-induced mouse peritoneal macrophages

J. Um, H. M. Kim, Seung-Heon Hong, 2008 .

Polymorphisms of RANTES and IL-4 Genes in Cerebral Infarction

J. Um, Hyung‐Min Kim, 2008, Journal of Molecular Neuroscience.

Effect of Korean folk medicine 'SecSec' on inflammatory cytokine secretion in HMC-1 cells

Seunghun Hong, J. Um, H. M. Kim, 2005 .

Frequencies of interleukin 1 gene polymorphisms in Koreans.

J. Um, H. M. Kim, 2003, Clinical chemistry.

LIPI 27(4).book(LIPI_A_141878.fm)

J. Um, Su-jin Kim, Seung-Heon Hong, 2005 .

Beneficial effects of the traditional medicine Igongsan and its constituent ergosterol on dextran sulfate sodium-induced colitis in mice.

J. Um, Jinbong Park, Hye-Lin Kim, 2015, Molecular medicine reports.

Saengmaeksan inhibits inflammatory mediators by suppressing RIP-2/caspase-1 activation

K. Ahn, J. Um, Sung-Hoon Kim, 2013, Immunopharmacology and immunotoxicology.

Eucommiae cortex inhibits TNF-α and IL-6 through the suppression of caspase-1 in lipopolysaccharide-stimulated mouse peritoneal macrophages.

K. Ahn, J. Um, H. Jang, 2012, The American journal of Chinese medicine.

Antiinflammatory Effect of Oldenlandia diffusa and its Constituent, Hentriacontane, through Suppression of Caspase‐1 Activation in Mouse Peritoneal Macrophages

J. Um, Su-jin Kim, Sung-soo Kim, 2011, Phytotherapy research : PTR.

Vanillic acid inhibits inflammatory mediators by suppressing NF-κB in lipopolysaccharide-stimulated mouse peritoneal macrophages

J. Um, Dae-Seung Kim, Yong-Deok Jeon, 2011, Immunopharmacology and immunotoxicology.

Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and STAT3

K. Ahn, J. Um, Jinbong Park, 2022, Cell Death & Disease.

Insamhodo-tang, a traditional Korean medicine, regulates mast cell-mediated allergic inflammation in vivo and in vitro.

J. Um, Ji-Ye Kee, Dae-Seung Kim, 2011, Journal of ethnopharmacology.

Anti-inflammatory activity of hyperoside through the suppression of nuclear factor-κB activation in mouse peritoneal macrophages.

J. Um, Su-jin Kim, Ju-Young Lee, 2011, The American journal of Chinese medicine.

Fangchinoline diminishes STAT3 activation by stimulating oxidative stress and targeting SHP-1 protein in multiple myeloma model

G. Sethi, K. Ahn, J. Um, 2021, Journal of Advanced Research.

Effects of hydrolyzed Chlorella vulgaris by malted barley on the immunomodulatory response in ICR mice and in Molt-4 cells.

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2010, Journal of the science of food and agriculture.

Angelica dahurica ameliorates the inflammation of gingival tissue via regulation of pro-inflammatory mediators in experimental model for periodontitis.

Hye Ji Lee, K. Ahn, J. Um, 2017, Journal of Ethnopharmacology.

Hot water extracts of Chlorella vulgaris improve immune function in protein-deficient weanling mice and immune cells

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2010, Immunopharmacology and immunotoxicology.

Regulatory role of Wdr24 in autophagy activity during zebrafish embryogenesis

J. Um, S. Choe, In-Koo Nam, 2018, Molecular & Cellular Toxicology.

Ixeris dentata NAKAI Reduces Clinical Score and HIF-1 Expression in Experimental Colitis in Mice

J. Um, Yo-Han Han, Dae-Seung Kim, 2013, Evidence-based complementary and alternative medicine : eCAM.

Lithospermi radix Extract Inhibits Histamine Release and Production of Inflammatory Cytokine in Mast Cells

Eun-Young Kim, J. Um, P. Moon, 2007, Bioscience, biotechnology, and biochemistry.

Dokhwaljihwang-tang inhibits LPS-induced inflammatory cytokine production in peripheral blood mononuclear cells

Myong-Jo Kim, J. Um, Su-jin Kim, 2010, Neurological research.

Alginic acid has anti‐anaphylactic effects and inhibits inflammatory cytokine expression via suppression of nuclear factor‐κB activation

J. Um, P. Moon, H. Na, 2006, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

Therapeutic role of Glycyrrhiza Uralensis fisher on benign prostatic hyperplasia through 5 alpha reductase regulation and apoptosis.

K. Ahn, J. Um, Jinbong Park, 2022, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Alpha-Pinene Exhibits Anti-Inflammatory Activity Through the Suppression of MAPKs and the NF-κB Pathway in Mouse Peritoneal Macrophages.

J. Um, Sung-Hoon Kim, Yo-Han Han, 2015, The American journal of Chinese medicine.

Scrophularia buergeriana regulates cytokine production in vitro

Dong-Hyun Kim, J. Um, Su-jin Kim, 2009, Immunopharmacology and immunotoxicology.

Mountain grown ginseng induces apoptosis in HL-60 cells and its mechanism have little relation with TNF-alpha production.

Deok-Chun Yang, J. Um, Seung-Heon Hong, 2007, The American journal of Chinese medicine.

Betula platyphylla attenuated mast cell-mediated allergic inflammation in vivo and in vitro.

J. Um, Su-jin Kim, Seung-Heon Hong, 2012, Life sciences.

Activation of inducible nitric oxide synthase by Kagamjuaguiem in peritoneal macrophages in mice.

J. Um, Sejin Jeong, Seung-Heon Hong, 2007, The Indian journal of medical research.

Immunomodulatory effects of Pseudostellaria heterophylla (Miquel) Pax on regulation of Th1/Th2 levels in mice with atopic dermatitis

K. Ahn, J. Um, Seok-Geun Lee, 2016, Molecular medicine reports.

Transgenic Panax ginseng inhibits the production of TNF-alpha, IL-6, and IL-8 as well as COX-2 expression in human mast cells.

Deok-Chun Yang, J. Um, Su-jin Kim, 2007, The American journal of Chinese medicine.

Libanoridin inhibits the mast cell-mediated allergic inflammatory reaction

J. Um, Sung-Hoon Kim, Su-jin Kim, 2010, Immunopharmacology and immunotoxicology.

Anti-inflammatory effect of Columbianetin on activated human mast cells.

J. Um, Su-jin Kim, Seung-Heon Hong, 2009, Biological & pharmaceutical bulletin.

Interleukin‐1 Beta Gene Polymorphism Related with Allergic Pathogenesis in Iris Constitution

J. Um, Cheorl-Ho Kim, Seung-Heon Hong, 2004, Immunopharmacology and immunotoxicology.

Involvement of protein kinase C in the inhibition of nitric oxide production from murine microglial cells by glucocorticoid.

C. Jun, J. Um, T. Y. Kim, 1994, Biochemical and biophysical research communications.

Eclipta prostrata Improves DSS-Induced Colitis through Regulation of Inflammatory Response in Intestinal Epithelial Cells.

J. Um, Yo-Han Han, Ji-Ye Kee, 2017, The American journal of Chinese medicine.

Panax ginseng C.A. meyer alleviates benign prostatic hyperplasia while preventing finasteride-induced side effects

K. Ahn, J. Um, Jinbong Park, 2023, Frontiers in Pharmacology.

The Multi‐Targeted Effects of Chrysanthemum Herb Extract Against Escherichia coli O157:H7

Ki-Suk Kim, Hea Jung Yang, Eun-Kyeong Choi, 2013, Phytotherapy research : PTR.

Ophiopogonin D modulates multiple oncogenic signaling pathways, leading to suppression of proliferation and chemosensitization of human lung cancer cells.

G. Sethi, K. Ahn, J. Um, 2018, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Brassinin enhances the anticancer actions of paclitaxel by targeting multiple signaling pathways in colorectal cancer cells

K. Ahn, J. Um, I. J. Ha, 2021, Phytotherapy research : PTR.

Fangchinoline, a Bisbenzylisoquinoline Alkaloid can Modulate Cytokine-Impelled Apoptosis via the Dual Regulation of NF-κB and AP-1 Pathways

G. Sethi, K. Ahn, J. Um, 2019, Molecules.

2,5-Dihydroxyacetophenone Induces Apoptosis of Multiple Myeloma Cells by Regulating the MAPK Activation Pathway

G. Sethi, K. Ahn, J. Um, 2017, Molecules.

Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades

G. Sethi, K. Ahn, J. Um, 2017, International journal of molecular sciences.

Ginkgolic Acid C 17:1, Derived from Ginkgo biloba Leaves, Suppresses Constitutive and Inducible STAT3 Activation through Induction of PTEN and SHP-1 Tyrosine Phosphatase

G. Sethi, K. Ahn, J. Um, 2017, Molecules.

Effects of the inhaled treatment of liriope radix on an asthmatic mouse model.

Hea Jung Yang, Eun-Kyeong Choi, Min-Hee Shin, 2015, The American journal of Chinese medicine.

Anti-inflammatory effects of Cheongilppong on DSS-induced ulcerative colitis in mice

J. Um, Dae-Seung Kim, Yong-Deok Jeon, 2011, Oriental Pharmacy & Experimental Medicine.

The Application of Embelin for Cancer Prevention and Therapy †

G. Sethi, K. Ahn, J. Um, 2018, Molecules.

Oral Administration of Hot Water Extracts of Chlorella vulgaris Increases Physical Stamina in Mice

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2006, Annals of Nutrition and Metabolism.

Inhibitory effects of chelidonic acid on IL-6 production by blocking NF-κB and caspase-1 in HMC-1 cells

J. Um, Hye-Lin Kim, Su-jin Kim, 2011, Immunopharmacology and immunotoxicology.

Genistein-4′-O-α-L-rhamnopyranosyl-(1→2)- β-D-glucopyranoside from Sophora japonica (Leguminosae) ameliorates mast cell-mediated allergic inflammation in vivo and in vitro

J. Um, Su-jin Kim, Seung-Heon Hong, 2011, Oriental Pharmacy and Experimental Medicine.

β-D-glucopyranoside from Sophora japonica (Leguminosae) ameliorates mast cell-mediated allergic inflammation in vivo and in vitro

J. Um, Su-jin Kim, Seung-Heon Hong, 2011 .

Hexane fraction of Citrus aurantium L. stimulates glucagon-like peptide-1 (GLP-1) secretion via membrane depolarization in NCI-H716 cells

Hyo-Weon Suh, Ki-Beom Lee, Ki-Suk Kim, 2012, BioChip Journal.

Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells.

J. Um, Seung-Heon Hong, Sang-Hyun Kim, 2007, International archives of allergy and immunology.

The Ameliorative Effect of Sophoricoside on Mast Cell-Mediated Allergic Inflammation in Vivo and in Vitro

J. Um, Sung-Hoon Kim, Su-jin Kim, 2013, Molecules.

Morusin induces cell death through inactivating STAT3 signaling in prostate cancer cells.

K. Ahn, J. Um, H. Jang, 2015, American journal of cancer research.

Inhibitory effects of Rumex japonicus Houtt. on the development of atopic dermatitis‐like skin lesions in NC/Nga mice

J. Um, B. Min, E-C Kim, 2006, The British journal of dermatology.

Use of scopoletin to inhibit the production of inflammatory cytokines through inhibition of the IkappaB/NF-kappaB signal cascade in the human mast cell line HMC-1.

J. Um, Seung-Heon Hong, Hyung-Ryong Kim, 2007, European journal of pharmacology.

The effect of Panax ginseng on forced immobility time & immune function in mice.

Deok-Chun Yang, J. Um, Seung-Heon Hong, 2006, The Indian journal of medical research.

Phytoestrogens induce apoptosis via extrinsic pathway, inhibiting nuclear factor-kappaB signaling in HER2-overexpressing breast cancer cells.

J. Um, H. Seo, H. Choi, 2011, Anticancer research.

Chrysophanic acid reduces testosterone-induced benign prostatic hyperplasia in rats by suppressing 5α-reductase and extracellular signal-regulated kinase

G. Sethi, K. Ahn, J. Um, 2016, Oncotarget.

Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer

G. Sethi, K. Ahn, J. Um, 2016, Oncotarget.

Effect of Gamiseunggal-Tang on immediate type allergic reaction in mice.

J. Um, Chang-Ju Kim, Seung-Heon Hong, 2007, The Indian journal of medical research.

Immune-enhancing effect of Danggwibohyeoltang, an extract from Astragali Radix and Angelicae gigantis Radix, in vitro and in vivo

J. Um, Su-jin Kim, Sung-soo Kim, 2012, Immunopharmacology and immunotoxicology.

Ethanol extract of Scutellaria baicalensis Georgi prevents oxidative damage and neuroinflammation and memorial impairments in artificial senescense mice

Yong-Cheol Shin, Namil Kim, Seong-Gyu Ko, 2011, Journal of Biomedical Science.

Anti-Inflammatory Activity of Chrysophanol through the Suppression of NF-κB/Caspase-1 Activation in Vitro and in Vivo

J. Um, Su-jin Kim, Seung-Heon Hong, 2010, Molecules.

Bitter Orange (Citrus aurantium Linné) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation

K. Ahn, J. Um, Jinbong Park, 2019, Nutrients.

Anti-obesity effects of Arctii Fructus (Arctium lappa) in white/brown adipocytes and high-fat diet-induced obese mice.

J. Um, Yo-Han Han, Ji-Ye Kee, 2016, Food & function.

Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2006, Journal of ethnopharmacology.

Hwanggunchungyitang prevents cadmium-induced ototoxicity through suppression of the activation of caspase-9 and extracellular signal-related kinase in auditory HEI-OC1 cells.

Dong-Hyun Kim, J. Um, H. So, 2009, Biological & pharmaceutical bulletin.

Ethanol extract of paeonia suffruticosa Andrews (PSE) induced AGS human gastric cancer cell apoptosis via fas-dependent apoptosis and MDM2-p53 pathways

Ji Hye Kim, Seong-Gyu Ko, J. Kim, 2012, Journal of Biomedical Science.

Berberine Improves Benign Prostatic Hyperplasia via Suppression of 5 Alpha Reductase and Extracellular Signal-Regulated Kinase in Vivo and in Vitro

J. Um, Jinbong Park, Yunu Jung, 2018, Front. Pharmacol..

Cinnamomi Cortex (Cinnamomum verum) Suppresses Testosterone-induced Benign Prostatic Hyperplasia by Regulating 5α-reductase

K. Ahn, J. Um, Seok-Geun Lee, 2016, Scientific Reports.

Conditioned media from adipocytes promote proliferation, migration, and invasion in melanoma and colorectal cancer cells

G. Sethi, K. Ahn, J. Um, 2019, Journal of cellular physiology.

Overexpression of Replication-Dependent Histone Signifies a Subset of Dedifferentiated Liposarcoma with Increased Aggressiveness

Murim Choi, J. Um, Yoon-La Choi, 2021, Cancers.

The Role of Resveratrol in Cancer Therapy

A. Bishayee, G. Sethi, K. Ahn, 2017, International journal of molecular sciences.

Inhibitory effect of quercetin on colorectal lung metastasis through inducing apoptosis, and suppression of metastatic ability.

J. Um, Yo-Han Han, Ji-Ye Kee, 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Anmyungambi Decoction Ameliorates Obesity through Activation of Non-Shivering Thermogenesis in Brown and White Adipose Tissues

J. Um, Jinbong Park, H. Kwak, 2022, Antioxidants.

Bergamottin Inhibits Adipogenesis in 3T3-L1 Cells and Weight Regulation in Diet-Induced Obese Mice.

K. Ahn, J. Um, Dongwoo Nam, 2018, The American journal of Chinese medicine.

Lipin1-Mediated Repression of Adipogenesis by Rutin.

J. Um, Yo-Han Han, Ji-Ye Kee, 2016, The American journal of Chinese medicine.

Corni Fructus Containing Formulation Attenuates Weight Gain in Mice with Diet-Induced Obesity and Regulates Adipogenesis through AMPK

J. Um, H. Jang, Jinbong Park, 2013, Evidence-based complementary and alternative medicine : eCAM.

Platycodin D, a novel activator of AMP-activated protein kinase, attenuates obesity in db/db mice via regulation of adipogenesis and thermogenesis.

K. Ahn, J. Um, Jinbong Park, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Anti-adipogenic effect of Glycoside St-E2 and Glycoside St-C1 isolated from the leaves of Acanthopanax henryi (Oliv.) Harms in 3T3-L1 cells

J. Um, Yo-Han Han, Seung-Heon Hong, 2016, Bioscience, biotechnology, and biochemistry.

Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

G. Sethi, K. Ahn, J. Um, 2017, Journal of cellular physiology.

Resveratrol attenuates constitutive STAT3 and STAT5 activation through induction of PTPε and SHP-2 tyrosine phosphatases and potentiates sorafenib-induced apoptosis in renal cell carcinoma

K. Ahn, J. Um, B. Shim, 2016, BMC Nephrology.

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer

Basappa, G. Sethi, K. Ahn, 2016, Apoptosis.

Telomerase: key regulator of inflammation and cancer.

K. Ahn, J. Um, Lele Wu, 2020, Pharmacological research.

The Protective Mechanism of Antioxidants in Cadmium-Induced Ototoxicity in Vitro and in Vivo

J. Um, H. So, Su-jin Kim, 2008, Environmental health perspectives.

Epigallocatechin-3-gallate suppresses NF-κB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells

J. Um, Su-jin Kim, Seung-Heon Hong, 2007 .

Ginkgetin Blocks Constitutive STAT3 Activation and Induces Apoptosis through Induction of SHP‐1 and PTEN Tyrosine Phosphatases

K. Ahn, J. Um, Dongwoo Nam, 2016, Phytotherapy research : PTR.

Casticin-Induced Inhibition of Cell Growth and Survival Are Mediated through the Dual Modulation of Akt/mTOR Signaling Cascade

G. Sethi, K. Ahn, J. Um, 2019, Cancers.

Interaction of Veratrum nigrum with Panax ginseng against Obesity: A Sang-ban Relationship

J. Um, Jinbong Park, Mi-Young Jeong, 2013, Evidence-based complementary and alternative medicine : eCAM.

Tanshinone IIA induces TRAIL sensitization of human lung cancer cells through selective ER stress induction.

K. Ahn, J. Um, S. Kang, 2016, International journal of oncology.

Embelin Inhibits Invasion and Migration of MDA‐MB‐231 Breast Cancer Cells by Suppression of CXC Chemokine Receptor 4, Matrix Metalloproteinases‐9/2, and Epithelial–Mesenchymal Transition

K. Ahn, J. Um, Dongwoo Nam, 2016, Phytotherapy research : PTR.

Potential Application of Leelamine as a Novel Regulator of Chemokine-Induced Epithelial-to-Mesenchymal Transition in Breast Cancer Cells

G. Sethi, K. Ahn, J. Um, 2022, International journal of molecular sciences.

Corilagin exhibits differential anticancer effects through the modulation of STAT3/5 and MAPKs in human gastric cancer cells

K. Ahn, J. Um, S. Hwang, 2022, Phytotherapy research : PTR.

Daidzin targets epithelial-to-mesenchymal transition process by attenuating manganese superoxide dismutase expression and PI3K/Akt/mTOR activation in tumor cells.

G. Sethi, K. Ahn, J. Um, 2022, Life sciences.

Identification of Matrine as a Novel Regulator of the CXCR4 Signaling Axis in Tumor Cells

K. Ahn, J. Um, A. Kumar, 2020, International journal of molecular sciences.

Loganic acid regulates the transition between epithelial and mesenchymal-like phenotypes by alleviating MnSOD expression in hepatocellular carcinoma cells.

G. Sethi, K. Ahn, J. Um, 2023, Life sciences.

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model.

G. Sethi, K. Ahn, J. Um, 2018, Cancer letters.

Electroacupuncture Protects against CCK-Induced Acute Pancreatitis in Rats

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2007, Neuroimmunomodulation.

Gamijeonssibaekchulsan regulates mast cell-mediated anaphylactic reaction.

J. Um, H. M. Kim, Seung-Heon Hong, 2007, Acta biochimica Polonica.

Sopoongsan Inhibits Mast Cell-Mediated Anaphylactic Reactions and Inflammatory Cytokine Secretion

Hye-Young Shin, Ho-Jeong Na, J. Um, 2005, International Archives of Allergy and Immunology.

Leelamine Modulates STAT5 Pathway Causing Both Autophagy and Apoptosis in Chronic Myelogenous Leukemia Cells

G. Sethi, K. Ahn, J. Um, 2022, Biology.

Blockage of the JAK/STAT3 signaling pathway in multiple myeloma by leelamine.

G. Sethi, K. Ahn, J. Um, 2021, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Bergamottin Suppresses Metastasis of Lung Cancer Cells through Abrogation of Diverse Oncogenic Signaling Cascades and Epithelial-to-Mesenchymal Transition

G. Sethi, K. Ahn, J. Um, 2018, Molecules.

Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade

G. Sethi, K. Ahn, J. Um, 2018, Front. Pharmacol..

Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

B. Goh, G. Sethi, Xiaoyun Dai, 2016, Molecular Cancer Therapeutics.

Resveratrol inhibits STAT3 signaling pathway through the induction of SOCS-1: Role in apoptosis induction and radiosensitization in head and neck tumor cells.

G. Sethi, K. Ahn, J. Um, 2016, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Brucein D imparts a growth inhibitory effect in multiple myeloma cells by abrogating the Akt‐driven signaling pathway

K. Ahn, J. Um, S. Rangappa, 2022, IUBMB life.

Pyrimethamine Modulates Interplay between Apoptosis and Autophagy in Chronic Myelogenous Leukemia Cells

K. Ahn, J. Um, Seok-Geun Lee, 2021, International journal of molecular sciences.

Withanolide modulates the potential crosstalk between apoptosis and autophagy in different colorectal cancer cell lines.

G. Sethi, K. Ahn, J. Um, 2022, European journal of pharmacology.

LDL cholesterol promotes the proliferation of prostate and pancreatic cancer cells by activating the STAT3 pathway

G. Sethi, K. Ahn, J. Um, 2020, Journal of cellular physiology.

Comparative transcriptomic analysis of the multi-targeted effects of the herbal extracts against Escherichia coli O157:H7

Ki-Suk Kim, Hea Jung Yang, Eun-Kyeong Choi, 2012, BioChip Journal.

The multi-target antibiotic efficacy of Angelica dahurica Bentham et Hooker extract exposed to the Escherichia coli O157:H7

Ki-Suk Kim, Hea Jung Yang, Eun-Kyeong Choi, 2011 .

Albiflorin ameliorates obesity by inducing thermogenic genes via AMPK and PI3K/AKT in vivo and in vitro.

R. Park, J. Um, Jinbong Park, 2017, Metabolism: clinical and experimental.

Expression of protein kinase C delta gene in germ cells.

J. Um, Byung-Min Choi, J. Rim, 1995, The Journal of urology.

Loss of pex5 sensitizes zebrafish to fasting due to deregulated mitochondria, mTOR, and autophagy

Seok-Hyung Kim, J. Um, D. Ryu, 2023, Cellular and Molecular Life Sciences.

Ginkgolide C promotes apoptosis and abrogates metastasis of colorectal carcinoma cells by targeting Wnt/β‐catenin signaling pathway

K. Ahn, J. Um, Seok-Geun Lee, 2021, IUBMB life.

Abrogation of STAT3 activation cascade by Ginkgolide C mitigates tumourigenesis in lung cancer preclinical model.

K. Ahn, J. Um, Seok-Geun Lee, 2021, The Journal of pharmacy and pharmacology.

Pharmacological effect of prohibited combination pair Panax ginseng and Veratrum nigrum on colorectal metastasis in vitro and in vivo.

J. Um, Yo-Han Han, Ji-Ye Kee, 2018, Journal of ethnopharmacology.

Protective effect of a Chrysanthemum indicum containing formulation in cadmium-induced ototoxicity.

J. Um, H. So, Su-jin Kim, 2011, The American journal of Chinese medicine.

Genetic susceptibility to ischemic cerebrovascular disease in Koreans

J. Um, Hyung‐Min Kim, N. An, 2003, Journal of Molecular Neuroscience.

GLUTATHIONE S-TRANSFERASE GENE POLYMORPHISM AND ISCHEMIC CEREBROVASCULAR DISEASE

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2006, The International journal of neuroscience.

Glutathione S-transferase polymorphisms and traditional classification in Korean population with cerebrovascular disease

J. Um, H. M. Kim, Seung-Heon Hong, 2004 .

Gamibojungikki-tang decreases immobility time on the forced swimming test and increases interferon-gamma production from MOLT-4 cells.

Deok-Chun Yang, J. Um, Seung-Heon Hong, 2005, Journal of ethnopharmacology.

Effect of Danchunwhangagam on LPS or DFX-Induced Cytokine Production in Peripheral Mononuclear Cells of Cerebral Infarction Patients

J. Um, Su-jin Kim, Seung-Heon Hong, 2005, Immunopharmacology and immunotoxicology.

TNF-α and TNF-β gene polymorphisms in cerebral infarction

J. Um, Hyung‐Min Kim, N. An, 2007, Journal of Molecular Neuroscience.

Glutathione S-transferase gene polymorphism in Korean subjects with gastric and colorectal cancer

J. Um, Yun-Kyung Kim, Hyun-Ju Kim, 2012, Oriental Pharmacy and Experimental Medicine.

Upregulation of neuronal astrocyte elevated gene-1 protects nigral dopaminergic neurons in vivo

Dong Woon Kim, P. Fisher, K. Ahn, 2018, Cell Death & Disease.

Gene-gene interaction in cerebral infarction patients: Relationship between apolipopreotein E gene polymorphism and Sasang-constitution

J. Um, H. M. Kim, Seung-Heon Hong, 2004 .

Angiotensin converting enzyme gene polymorphism and traditional Sasang classification in Koreans with cerebral infarction.

J. Um, Hyung‐Min Kim, N. An, 2003, Hereditas.

Polymorphism of angiotensin-converting enzyme gene and BMI in obese Korean women.

J. Um, Yung-sun Song, Hyung‐Min Kim, 2003, Clinica chimica acta; international journal of clinical chemistry.

The Effect of Hydrolyzed Spirulina by Malted Barley on Forced Swimming Test in ICR Mice

J. Um, Seung-Heon Hong, Ju-Young Lee, 2008, The International journal of neuroscience.

A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway.

K. Ahn, J. Um, Jinbong Park, 2020, Pharmacological research.

Aconiti Lateralis Radix Preparata, the Dried Root of Aconitum carmichaelii Debx., Improves Benign Prostatic Hyperplasia via Suppressing 5-Alpha Reductase and Inducing Prostate Cell Apoptosis

J. Um, Jinbong Park, D. Youn, 2019, Evidence-based complementary and alternative medicine : eCAM.

Albendazole Exhibits Anti-Neoplastic Actions against Gastric Cancer Cells by Affecting STAT3 and STAT5 Activation by Pleiotropic Mechanism(s)

K. Ahn, J. Um, M. Yang, 2021, Biomedicines.

3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 signaling through the induction of PIAS3

J. Um, Dongwoo Nam, Seok-Geun Lee, 2016, Immunopharmacology and immunotoxicology.

Platycodon grandiflorum A. De Candolle Ethanolic Extract Inhibits Adipogenic Regulators in 3T3-L1 Cells and Induces Mitochondrial Biogenesis in Primary Brown Preadipocytes.

J. Um, Jinbong Park, Mi-Young Jeong, 2015, Journal of agricultural and food chemistry.

(-)-Epigallocatechin-3-Gallate Protects against NO-Induced Ototoxicity through the Regulation of Caspase- 1, Caspase-3, and NF-κB Activation

R. Park, J. Um, H. So, 2012, PloS one.

Inhibitory effects of the transgenic Panax ginsengs on phorbol ester plus A23187-induced IL-6 production and cyclooxygenase-2 via suppression of NF-κB and MAPKs in HMC-1

Deok-Chun Yang, J. Um, Su-jin Kim, 2011, Immunopharmacology and immunotoxicology.

Embelin induces apoptosis in human glioma cells through inactivating NF-κB.

K. Ahn, J. Um, H. Jang, 2013, Journal of pharmacological sciences.

Inhibition of the PI3K-AKT-mTOR pathway suppresses the adipocyte-mediated proliferation and migration of breast cancer cells

K. Ahn, J. Um, S. Kang, 2020, Journal of Cancer.

Determination of the site of origin of Pinellia ternata roots based on RAPD analysis and PCR-RFLP.

Hwan-Suck Chung, J. Um, Seung-Heon Hong, 2002, Hereditas.

Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway.

K. Ahn, J. Um, S. Hwang, 2020, Life sciences.

Angiotensinogen Gene Polymorphism Predicts Hypertension, and Iridological Constitutional Classification Enhances the Risk for Hypertension in Koreans

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2008, The International journal of neuroscience.

The regulatory effect of SC-236 (4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1-pyrazol-1-l]benzenesulfonamide) on stem cell factor induced migration of mast cells.

J. Um, Su-jin Kim, Seung-Heon Hong, 2007, Toxicology and applied pharmacology.

Gumiganghwal-tang ameliorates cartilage destruction via inhibition of matrix metalloproteinase.

K. Ahn, J. Um, Seok-Geun Lee, 2020, Journal of ethnopharmacology.

Effect of Chlorella vulgaris on Immune-enhancement and Cytokine Production in vivo and in vitro

J. Um, Jong Hyun Lee, H. M. Kim, 2008 .

The protective effect of anti-oxidant in cadmium-induced hair cell death

J. Um, H. M. Kim, Su-jin Kim, 2009 .

Mori Folium regulates DSS-induced ulcerative colitis in mice and cytokine production in mast cells

J. Um, Ji-Ye Kee, Yong-Deok Jeon, 2012, Oriental Pharmacy and Experimental Medicine.

Typha orientalis inhibits inflammatory cytokine expression through suppression of ERK phosphorylation in HMC-1 cells

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2010 .

Mild NO preconditioning protects H9c2 cells against NO-induced apoptosis through activation of PI3K/Akt and PKA-dependent pathways

J. Um, Sang-Seob Lee, H. Kwak, 2019, Molecular & Cellular Toxicology.

The COX-2 inhibitor SC-236 exerts anti-inflammatory effects by suppressing phosphorylation of ERK in a murine model.

R. Park, J. Um, H. So, 2007, Life sciences.

Brassinin Induces Apoptosis, Autophagy, and Paraptosis via MAPK Signaling Pathway Activation in Chronic Myelogenous Leukemia Cells

G. Sethi, K. Ahn, J. Um, 2023, Biology.

Arctiin is a pharmacological inhibitor of STAT3 phosphorylation at tyrosine 705 residue and potentiates bortezomib-induced apoptotic and anti-angiogenic effects in human multiple myeloma cells.

G. Sethi, K. Ahn, J. Um, 2019, Phytomedicine : international journal of phytotherapy and phytopharmacology.

Study on prescriptions for pregnancy and childbirth of the royal family in Joseon dynasty

J. Um, Jinbong Park, Wung-Seok Cha, 2015, Oriental Pharmacy and Experimental Medicine.

Protective effect of rosmarinic acid is through regulation of inflammatory cytokine in cadmium-induced ototoxicity.

J. Um, Su-jin Kim, Seung-Heon Hong, 2013, The American journal of Chinese medicine.

Anti-inflammatory effect of jeongshintang through suppression of p38 activation in human astrocytoma, U373MG cells.

J. Um, B. K. Kim, N. Kim, 2006, Experimental and molecular pathology.

Synergistic Effect of Bupleuri Radix and Scutellariae Radix on Adipogenesis and AMP-Activated Protein Kinase: A Network Pharmacological Approach

J. Um, Jinbong Park, D. Youn, 2018, Evidence-based complementary and alternative medicine : eCAM.

Association among apolipoprotein E gene polymorphism, diabetes mellitus, and ischemic cerebrovascular disease in Koreans

J. Um, Sejin Jeong, Seung-Heon Hong, 2006 .

Antihyperglycemic and Antiobesity Effects of JAL2 on db/db Mice

Yun‐Cheol Na, K. Ahn, J. Um, 2016, Evidence-based complementary and alternative medicine : eCAM.

Interleukin-1 Beta Gene Polymorphism and Traditional Constitution in Obese Women

J. Um, Seung-Heon Hong, Jeong‐Hoon Lee, 2008, The International journal of neuroscience.

Association of a multidrug resistance 1 gene polymorphism and colorectal cancer in the Korean population

J. Um, Yun-Kyung Kim, Hyun-Ju Kim, 2013, Oriental Pharmacy and Experimental Medicine.

Igongsan reduces testosterone-induced benign prostate hyperplasia by regulating 5α-reductase in rats

J. Um, Jinbong Park, Yunu Jung, 2018, Molecular & Cellular Toxicology.

Ginkgolic Acid Inhibits Invasion and Migration and TGF‐β‐Induced EMT of Lung Cancer Cells Through PI3K/Akt/mTOR Inactivation

G. Sethi, K. Ahn, J. Um, 2017, Journal of cellular physiology.

Euphorbiasteroid Induces Apoptosis as Well as Autophagy through Modulating SHP-1/STAT3 Pathway in Hepatocellular Carcinoma Cells

G. Sethi, K. Ahn, J. Um, 2023, International journal of molecular sciences.

Angiotensinogen Gene Polymorphism Predicts Hypertension, and Iridological Constitutional Classification Enhances the Risk for Hypertension in Koreans

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2008, The International journal of neuroscience.

Protective mechanism of Korean Red Ginseng in cisplatin-induced ototoxicity through attenuation of nuclear factor-κB and caspase-1 activation.

J. Um, Sung-Hoon Kim, Su-jin Kim, 2015, Molecular medicine reports.

Regulatory role of Wdr24 in autophagy activity during zebrafish embryogenesis

J. Um, Yong-Il Kim, In‐Koo Nam, 2018, Molecular & Cellular Toxicology.

The Antiinflammatory Mechanism of Igongsan in Mouse Peritoneal Macrophages via Suppression of NF‐κB/Caspase‐1 Activation

J. Um, Jinbong Park, Mi-Young Jeong, 2014, Phytotherapy research : PTR.

Epigallocatechin-3-gallate suppresses NF-kappaB activation and phosphorylation of p38 MAPK and JNK in human astrocytoma U373MG cells.

J. Um, Seung-Heon Hong, Hyung‐Min Kim, 2007, The Journal of nutritional biochemistry.

Fangchinoline targets human renal cell carcinoma cells through modulation of apoptotic and non‑apoptotic cell deaths.

J. Um, S. Baek, Y. Y. Jung, 2024, Pathology, research and practice.

Cycloastragenol exerts protective effects against UVB irradiation in human dermal fibroblasts and HaCaT keratinocytes.

K. Ahn, J. Um, S. Hwang, 2023, Journal of dermatological science.