Zhenggang Zhang

S. Mayer, M. Chopp, Q. Jiang, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Vepoloxamer Enhances Fibrinolysis of tPA (Tissue-Type Plasminogen Activator) on Acute Ischemic Stroke.

M. Chopp, Zhenggang Zhang, Mei Lu, 2019, Stroke.

Atorvastatin Extends the Therapeutic Window for tPA to 6 h after the Onset of Embolic Stroke in Rats

M. Chopp, Zhenggang Zhang, Mei Lu, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Adjuvant Treatment With Neuroserpin Increases the Therapeutic Window for Tissue-Type Plasminogen Activator Administration in a Rat Model of Embolic Stroke

M. Chopp, Q. Jiang, Zhenggang Zhang, 2002, Circulation.

Magnetic Resonance Imaging and Modeling of the Glymphatic System

M. Chopp, Q. Jiang, Zhenggang Zhang, 2020, Diagnostics.

Ascl1 Lineage Cells Contribute to Ischemia-Induced Neurogenesis and Oligodendrogenesis

M. Chopp, Zhenggang Zhang, Mei Lu, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Functional Recovery in Aged and Young Rats After Embolic Stroke: Treatment With a Phosphodiesterase Type 5 Inhibitor

M. Chopp, Zhenggang Zhang, Li Zhang, 2005, Stroke.

Neurorestorative therapies for stroke: underlying mechanisms and translation to the clinic

M. Chopp, Zhenggang Zhang, 2009, The Lancet Neurology.

Intravenous Administration of Human Umbilical Cord Blood‐Derived AC133+ Endothelial Progenitor Cells in Rat Stroke Model Reduces Infarct Volume: Magnetic Resonance Imaging and Histological Findings

R. Knight, J. Ewing, Zhenggang Zhang, 2013, Stem cells translational medicine.

Combination therapy of stroke in rats with a nitric oxide donor and human bone marrow stromal cells enhances angiogenesis and neurogenesis

M. Chopp, Zhenggang Zhang, Mei Lu, 2004, Brain Research.

Intravenous Administration of a GPIIb/IIIa Receptor Antagonist Extends the Therapeutic Window of Intra-Arterial Tenecteplase–Tissue Plasminogen Activator in a Rat Stroke Model

M. Chopp, Zhenggang Zhang, Li Zhang, 2004, Stroke.

Duration dependent post-ischemic hypothermia alleviates cortical damage after transient middle cerebral artery occlusion in the rat

M. Chopp, Zhenggang Zhang, Hua Chen, 1993, Journal of the Neurological Sciences.

A test for detecting long-term sensorimotor dysfunction in the mouse after focal cerebral ischemia

Michael Chopp, Mei Lu, Quan Jiang, 2002, Journal of Neuroscience Methods.

Delayed treatment with sildenafil enhances neurogenesis and improves functional recovery in aged rats after focal cerebral ischemia

M. Chopp, Zhenggang Zhang, Li Zhang, 2006, Journal of neuroscience research.

Mesenchymal Stem Cell–Derived Exosomes Improve Functional Recovery in Rats After Traumatic Brain Injury: A Dose-Response and Therapeutic Window Study

M. Chopp, Zhenggang Zhang, A. Mahmood, 2020, Neurorehabilitation and neural repair.

Bone Marrow Stromal Cells Enhance Inter- and Intracortical Axonal Connections after Ischemic Stroke in Adult Rats

M. Chopp, Zhenggang Zhang, Mei Lu, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Brain Repair and Recovery from Stroke

M. Chopp, Zhenggang Zhang, Yi Li, 2008 .

Ischemic cerebral tissue and MCP-1 enhance rat bone marrow stromal cell migration in interface culture.

M. Chopp, Zhenggang Zhang, Mei Lu, 2002, Experimental hematology.

Mean microvessel segment length and radius after embolic stroke: Comparison of magnetic resonance imaging (MRI) and laser scanning confocal microscopy (LSCM)

M. Chopp, Q. Jiang, Zhenggang Zhang, 2011, Brain Research.

Focal embolic cerebral ischemia in the rat

M. Chopp, Q. Jiang, Zhenggang Zhang, 2015, Nature Protocols.

Stroke Plasminogen Activator Treatment Alone and in Combination in a Rat Embolic Model of Effects of a Selective CD 11 b / CD 18 Antagonist and Recombinant Human Tissue

M. Krams, M. Chopp, Zhenggang Zhang, 2003 .

Characterizing Brain Structures and Remodeling after TBI Based on Information Content, Diffusion Entropy

N. Lehman, M. Chopp, D. Hearshen, 2013, PloS one.

Erythropoietin in Combination of Tissue Plasminogen Activator Exacerbates Brain Hemorrhage When Treatment Is Initiated 6 Hours After Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2010, Stroke.

Dynamic platelet accumulation at the site of the occluded middle cerebral artery and in downstream microvessels is associated with loss of microvascular integrity after embolic middle cerebral artery occlusion

M. Chopp, Zhenggang Zhang, B. Coller, 2001, Brain Research.

Adjuvant Treatment With a Glycoprotein IIb/IIIa Receptor Inhibitor Increases the Therapeutic Window for Low-Dose Tissue Plasminogen Activator Administration in a Rat Model of Embolic Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2003, Circulation.

Treatment of acute stroke with recombinant tissue plasminogen activator and abciximab.

Zhenggang Zhang, Mei Lu, Suresh Patel, 2003, Academic emergency medicine : official journal of the Society for Academic Emergency Medicine.

The temporal profiles of ICAM-1 protein and mRNA expression after transient MCA occlusion in the rat

M. Chopp, A. Manning, Zhenggang Zhang, 1995, Brain Research.

Do Leukocytes Contribute to the Brain Lesion That Begins When an Intracranial Artery Is Occluded

M. Chopp, J. Garcìa, Zhenggang Zhang, 1994 .

11 – Enhancing Brain Reorganization and Recovery of Function after Stroke

M. Chopp, Zhenggang Zhang, 2011 .

Stroke Induces Gene Profile Changes Associated with Neurogenesis and Angiogenesis in Adult Subventricular Zone Progenitor Cells

M. Chopp, Zhenggang Zhang, X. Liu, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Coupling of Angiogenesis and Neurogenesis in Cultured Endothelial Cells and Neural Progenitor Cells after Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Combination of Surgical Resection and Photodynamic Therapy of 9L Gliosarcoma in the Nude Rat

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2006 .

Combination of Surgical Resection and Photodynamic Therapy of 9L Gliosarcoma in the Nude Rat

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2006, Photochemistry and photobiology.

Combination Therapy With VELCADE and Tissue Plasminogen Activator Is Neuroprotective in Aged Rats After Stroke and Targets MicroRNA-146a and the Toll-Like Receptor Signaling Pathway

M. Chopp, Zhenggang Zhang, Li Zhang, 2012, Arteriosclerosis, thrombosis, and vascular biology.

Atorvastatin Downregulates Tissue Plasminogen Activator-Aggravated Genes Mediating Coagulation and Vascular Permeability in Single Cerebral Endothelial Cells Captured by Laser Microdissection

M. Chopp, Zhenggang Zhang, A. Kapke, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Ischemic Cerebral Tissue Response to Subventricular Zone Cell Transplantation Measured by Iterative Self-Organizing Data Analysis Technique Algorithm

M. Chopp, J. Ewing, Q. Jiang, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents

M. Chopp, J. Griffin, Zhenggang Zhang, 2012, Stroke.

MicroRNAs in the axon locally mediate the effects of chondroitin sulfate proteoglycans and cGMP on axonal growth

M. Chopp, Zhenggang Zhang, X. Liu, 2015, Developmental neurobiology.

miR-146a mediates thymosin β4 induced neurovascular remodeling of diabetic peripheral neuropathy in type-II diabetic mice

Kuan-Han H Wu, M. Chopp, Zhenggang Zhang, 2019, Brain Research.

Mesenchymal stromal cell-derived exosomes ameliorate peripheral neuropathy in a mouse model of diabetes

M. Chopp, Zhenggang Zhang, X. Liu, 2019, Diabetologia.

Plasminogen deficiency causes reduced angiogenesis and behavioral recovery after stroke in mice

M. Chopp, Zhenggang Zhang, Li Zhang, 2021, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Angiogenesis Detected After Embolic Stroke in Rat Brain Using Magnetic Resonance T2*WI

M. Chopp, J. Ewing, Q. Jiang, 2008, Stroke.

Differences between normal and diabetic brains in middle-aged rats by MRI

M. Chopp, Q. Jiang, Zhenggang Zhang, 2019, Brain Research.

Emerging potential of exosomes and noncoding microRNAs for the treatment of neurological injury/diseases

M. Chopp, Zhenggang Zhang, 2015, Expert opinion on emerging drugs.

Thymosin β4 Up-regulation of MicroRNA-146a Promotes Oligodendrocyte Differentiation and Suppression of the Toll-like Proinflammatory Pathway*

M. Chopp, Zhenggang Zhang, M. Santra, 2014, The Journal of Biological Chemistry.

SDF-1 and CXCR4 are up-regulated by VEGF and contribute to glioma cell invasion.

T. Mikkelsen, M. Chopp, S. Kalkanis, 2006, Cancer letters.

Thymosin beta 4 mediates oligodendrocyte differentiation by upregulating p38 MAPK

M. Chopp, Zhenggang Zhang, Mei Lu, 2012, Glia.

A Quantitative Model of Tumor-induced Angiogenesis in the Nude Mouse

T. Mikkelsen, M. Chopp, S. Kalkanis, 2005, Neurosurgery.

L. McCullough, Zhenggang Zhang, Yi Zhang, 2018, Translational Stroke Research.

MiR-146a promotes oligodendrocyte progenitor cell differentiation and enhances remyelination in a model of experimental autoimmune encephalomyelitis

M. Chopp, Zhenggang Zhang, Mei Lu, 2019, Neurobiology of Disease.

Regulation of serum response factor by miRNA‐200 and miRNA‐9 modulates oligodendrocyte progenitor cell differentiation

M. Chopp, Zhenggang Zhang, Rui Zhang, 2012, Glia.

11 – Mechanisms of Plasticity, Remodeling and Recovery

M. Chopp, Zhenggang Zhang, 2016 .

Ischemic stroke and neurogenesis in the subventricular zone

M. Chopp, Zhenggang Zhang, R. Zhang, 2008, Neuropharmacology.

Tumor Necrosis Factor α Primes Cerebral Endothelial Cells for Erythropoietin-Induced Angiogenesis

M. Chopp, Zhenggang Zhang, Lei Wang, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Angiogenesis Induced by Photodynamic Therapy in Normal Rat Brain ¶

M. Chopp, Zhenggang Zhang, M. Katakowski, 2004 .

Dopachrome tautomerase (Dct) regulates neural progenitor cell proliferation.

M. Chopp, Zhenggang Zhang, Lei Wang, 2006, Developmental biology.

MiR-17-92 enriched exosomes derived from multipotent mesenchymal stromal cells enhance axon-myelin remodeling and motor electrophysiological recovery after stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2020, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Increased chemotactic migration and growth in heparanase-overexpressing human U251n glioma cells

T. Mikkelsen, M. Chopp, S. Kalkanis, 2008, Journal of experimental & clinical cancer research : CR.

MRI evaluation of axonal reorganization after bone marrow stromal cell treatment of traumatic brain injury

Michael Chopp, Zhifeng Kou, Mei Lu, 2011, NMR in biomedicine.

Angiogenesis and Functional Recovery After Traumatic Brain Injury

M. Chopp, Zhenggang Zhang, A. Mahmood, 2014 .

Cerebral vessels express interleukin 1β after focal cerebral ischemia

M. Chopp, Zhenggang Zhang, C. Powers, 1998, Brain Research.

Endogenous plasminogen activator expression after embolic focal cerebral ischemia in mice

M. Chopp, Zhenggang Zhang, W. Tsang, 1999, Brain Research.

Angiogenesis and improved cerebral blood flow in the ischemic boundary area detected by MRI after administration of sildenafil to rats with embolic stroke

M. Chopp, J. Ewing, Q. Jiang, 2007, Brain Research.

Fingolimod treatment promotes proliferation and differentiation of oligodendrocyte progenitor cells in mice with experimental autoimmune encephalomyelitis

M. Chopp, Zhenggang Zhang, Mei Lu, 2015, Neurobiology of Disease.

Oligodendrogenesis after cerebral ischemia

M. Chopp, Zhenggang Zhang, RuiLan Zhang, 2013, Front. Cell. Neurosci..

Angiogenesis Induced by Photodynamic Therapy in Normal Rat Brain¶

Fan Zhang, Michael Chopp, Feng Jiang, 2004, Photochemistry and photobiology.

Post-acute response of 9L gliosarcoma to Photofrin™-mediated PDT in athymic nude mice

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2007, Lasers in Medical Science.

Low-dose photodynamic therapy increases endothelial cell proliferation and VEGF expression in nude mice brain

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2005, Lasers in Medical Science.

Treatment of traumatic brain injury in rats with erythropoietin and carbamylated erythropoietin.

M. Chopp, Zhenggang Zhang, D. Lu, 2007, Journal of neurosurgery.

Mechanisms underlying improved recovery of neurological function after stroke in the rodent after treatment with neurorestorative cell-based therapies.

M. Chopp, Zhenggang Zhang, Yi Li, 2009, Stroke.

Bone Marrow Stromal Cells Increase Oligodendrogenesis after Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Up-Regulation of Neuropilin-1 in Neovasculature after Focal Cerebral Ischemia in the Adult Rat

M. Chopp, Zhenggang Zhang, C. Powers, 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Expression of glial fibrillary acidic protein in areas of focal cerebral ischemia accompanies neuronal expression of 72-kDa heat shock protein

M. Chopp, Zhenggang Zhang, Yi Li, 1995, Journal of the Neurological Sciences.

Multipotent Mesenchymal Stromal Cells Increase tPA Expression and Concomitantly Decrease PAI-1 Expression in Astrocytes through the Sonic Hedgehog Signaling Pathway after Stroke (in vitro Study)

M. Chopp, Zhenggang Zhang, Yi Li, 2011, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Down-regulation of p27kip1 increases proliferation of progenitor cells in adult rats

M. Chopp, Zhenggang Zhang, Lei Wang, 2004, Neuroreport.

Sonic Hedgehog Signaling Pathway Mediates Cerebrolysin-Improved Neurological Function After Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2013, Stroke.

Treatment of embolic stroke in rats with bortezomib and recombinant human tissue plasminogen activator

M. Chopp, Zhenggang Zhang, Mei Lu, 2005, Thrombosis and Haemostasis.

MicroRNAs in cerebral ischemia-induced neurogenesis.

M. Chopp, Zhenggang Zhang, X. Liu, 2013, Journal of neuropathology and experimental neurology.

and Model of Embolic Stroke RatTherapeutic Window for Low-Dose Tissue Plasminogen Activator Administration in a Adjuvant Treatment With a Glycoprotein IIb / IIIa Receptor Inhibitor Increases the

M. Chopp, Zhenggang Zhang, Mei Lu, 2003 .

Functional response to SDF1α through over-expression of CXCR4 on adult subventricular zone progenitor cells

M. Chopp, Zhenggang Zhang, Mei Lu, 2008, Brain Research.

Thymosin β4 as a restorative/regenerative therapy for neurological injury and neurodegenerative diseases

M. Chopp, Zhenggang Zhang, 2015, Expert opinion on biological therapy.

The MicroRNA-17–92 Cluster Enhances Axonal Outgrowth in Embryonic Cortical Neurons

M. Chopp, Zhenggang Zhang, X. Liu, 2013, The Journal of Neuroscience.

Stroke Increases Neural Stem Cells and Angiogenesis in the Neurogenic Niche of the Adult Mouse

M. Chopp, Zhenggang Zhang, Xianshuang Liu, 2014, PloS one.

Thymosin β4 promotes the recovery of peripheral neuropathy in type II diabetic mice

M. Chopp, Zhenggang Zhang, Mei Lu, 2012, Neurobiology of Disease.

Exosomes Derived From Schwann Cells Ameliorate Peripheral Neuropathy in Type 2 Diabetic Mice

M. Chopp, Zhenggang Zhang, Mei Lu, 2020, Diabetes.

Tadalafil Promotes the Recovery of Peripheral Neuropathy in Type II Diabetic Mice

M. Chopp, Zhenggang Zhang, Mei Lu, 2016, PloS one.

Delayed thrombosis after traumatic brain injury in rats.

M. Chopp, Zhenggang Zhang, D. Lu, 2004, Journal of neurotrauma.

Stroke-Induced Subventricular Zone Proliferation is Promoted by Tumor Necrosis Factor-α-Converting Enzyme Protease Activity

M. Chopp, Zhenggang Zhang, Jieli Chen, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Three-dimensional measurement of cerebral microvascular plasma perfusion, glial fibrillary acidic protein and microtubule associated protein-2 immunoreactivity after embolic stroke in rats: a double fluorescent labeled laser-scanning confocal microscopic study

M. Chopp, J. Windham, Zhenggang Zhang, 1999, Brain Research.

Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury.

M. Chopp, T. Schallert, Zhenggang Zhang, 2004, Journal of neurosurgery.

Combination Treatment With N-Acetyl-Seryl-Aspartyl-Lysyl-Proline and Tissue Plasminogen Activator Provides Potent Neuroprotection in Rats After Stroke

M. Chopp, Q. Jiang, Zhenggang Zhang, 2014, Stroke.

Cerebral endothelial cell derived small extracellular vesicles improve cognitive function in aged diabetic rats

M. Chopp, Zhenggang Zhang, Mei Lu, 2022, Frontiers in Aging Neuroscience.

Neural Progenitor Cells Treated with EPO Induce Angiogenesis through the Production of Vegf

M. Chopp, Zhenggang Zhang, Lei Wang, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Phosphoinositide 3‐kinase promotes adult subventricular neuroblast migration after stroke

M. Chopp, Zhenggang Zhang, Yi Li, 2003, Journal of neuroscience research.

Treatment of Traumatic Brain Injury with Vepoloxamer (Purified Poloxamer 188).

M. Chopp, Zhenggang Zhang, Mei Lu, 2018, Journal of neurotrauma.

Demonstration of therapeutic window of Cerebrolysin in embolic stroke: A prospective, randomized, blinded, and placebo-controlled study

M. Chopp, Zhenggang Zhang, Mei Lu, 2017, International journal of stroke : official journal of the International Stroke Society.

Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models

M. Chopp, T. Schallert, S. Kalkanis, 2007, Behavioural Brain Research.

The treatment of TBI with human marrow stromal cells impregnated into collagen scaffold: Functional outcome and gene expression profile

M. Chopp, Bo Li, Zhenggang Zhang, 2011, Brain Research.

Pharmacological Characterization of a Novel Neuroactive Steroid Prodrug, NTS-104, and Its Neuroprotective Activity in Experimental Stroke Models

M. Chopp, T. Verdoorn, Zhenggang Zhang, 2022, Stroke.

Neuroprotective and neurorestorative effects of thymosin beta4 treatment initiated 6 hours post injury following traumatic brain injury in rats

M. Chopp, Zhenggang Zhang, A. Mahmood, 2012 .

Erythropoietin Amplifies Stroke-Induced Oligodendrogenesis in the Rat

M. Chopp, Zhenggang Zhang, Mei Lu, 2010, PloS one.

Cerebral Artery Occlusion

M. Chopp, Zhenggang Zhang, RuiLan Zhang, 2005 .

Erythropoietin up-regulates SOCS2 in neuronal progenitor cells derived from SVZ of adult rat

M. Chopp, Zhenggang Zhang, M. Hafner, 2004, Neuroreport.

EphB2 induces proliferation and promotes a neuronal fate in adult subventricular neural precursor cells

M. Chopp, Zhenggang Zhang, M. Katakowski, 2005, Neuroscience Letters.

Postischemic (1 Hour) Hypothermia Significantly Reduces Ischemic Cell Damage in Rats Subjected to 2 Hours of Middle Cerebral Artery Occlusion

M. Chopp, J. Garcìa, Zhenggang Zhang, 1993, Stroke.

A rat model of focal embolic cerebral ischemia

Michael Chopp, Quan Jiang, Rui Lan Zhang, 1997, Brain Research.

Reduction of the Cell Cycle Length by Decreasing G1 Phase and Cell Cycle Reentry Expand Neuronal Progenitor Cells in the Subventricular Zone of Adult Rat after Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Receptor tyrosine kinase tie 1 mRNA is upregulated on cerebral microvessels after embolic middle cerebral artery occlusion in rat

M. Chopp, Zhenggang Zhang, D. Lu, 1999, Brain Research.

MicroRNA-146a Mimics Reduce the Peripheral Neuropathy in Type 2 Diabetic Mice

M. Chopp, Jiani Hu, Zhenggang Zhang, 2017, Diabetes.

MiR-29c/PRKCI Regulates Axonal Growth of Dorsal Root Ganglia Neurons Under Hyperglycemia

M. Chopp, Zhenggang Zhang, Lei Wang, 2017, Molecular Neurobiology.

Therapeutic effect of Cerebrolysin on reducing impaired cerebral endothelial cell permeability

M. Chopp, Zhenggang Zhang, Mei Lu, 2021, Neuroreport.

Cerebrolysin enhances neurogenesis in the ischemic brain and improves functional outcome after stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2010, Journal of neuroscience research.

Neuronal survival is associated with 72-kDa heat shock protein expression after transient middle cerebral artery occlusion in the rat

M. Chopp, Zhenggang Zhang, Yi Li, 1993, Journal of the Neurological Sciences.

Waste Clearance in the Brain

M. Chopp, Q. Jiang, Zhenggang Zhang, 2021, Frontiers in Neuroanatomy.

Intracellular free calcium mediates glioma cell detachment and cytotoxicity after photodynamic therapy

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2009, Lasers in Medical Science.

Intrastriatal Transplantation of Bone Marrow Nonhematopoietic Cells Improves Functional Recovery After Stroke in Adult Mice

M. Chopp, Zhenggang Zhang, Yi Li, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Synergistic Effect of an Endothelin Type A Receptor Antagonist, S-0139, With rtPA on the Neuroprotection After Embolic Stroke

M. Chopp, Zhenggang Zhang, A. Kapke, 2008, Stroke.

Neuroprotective and neurorestorative effects of thymosin β4 treatment initiated 6 hours after traumatic brain injury in rats.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2012, Journal of neurosurgery.

Matrix Metalloproteinase 2 (MMP2) and MMP9 Secreted by Erythropoietin-Activated Endothelial Cells Promote Neural Progenitor Cell Migration

M. Chopp, Zhenggang Zhang, A. Hozeska-Solgot, 2006, The Journal of Neuroscience.

Emerging Roles of microRNAs as Biomarkers and Therapeutic Targets for Diabetic Neuropathy

M. Chopp, Zhenggang Zhang, X. Liu, 2020, Frontiers in Neurology.

Treatment of traumatic brain injury with thymosin β₄ in rats.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2011, Journal of neurosurgery.

Neural Stem Cells and Ischemic Brain

M. Chopp, Zhenggang Zhang, 2016, Journal of stroke.

Systemic administration of exosomes released from mesenchymal stromal cells promote functional recovery and neurovascular plasticity after stroke in rats

M. Chopp, Zhenggang Zhang, Yi Li, 2013, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

P-selectin antibody reduces hemorrhage and infarct volume resulting from MCA occlusion in the rat

Michael Chopp, M. Chopp, Zhenggang Zhang, 1998, Journal of the Neurological Sciences.

E-Selectin in Focal Cerebral Ischemia and Reperfusion in the Rat

M. Chopp, A. Manning, Zhenggang Zhang, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Correlation of VEGF and Angiopoietin Expression with Disruption of Blood–Brain Barrier and Angiogenesis after Focal Cerebral Ischemia

Hamid Soltanian-Zadeh, Michael Chopp, Li Zhang, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Cerebral Microvascular Obstruction by Fibrin is Associated with Upregulation of PAI-1 Acutely after Onset of Focal Embolic Ischemia in Rats

M. Chopp, Zhenggang Zhang, C. Powers, 1999, The Journal of Neuroscience.

The neurovascular unit and combination treatment strategies for stroke.

M. Chopp, Zhenggang Zhang, Li Zhang, 2012, Trends in pharmacological sciences.

Tumor Necrosis Factor α Primes Cerebral Endothelial Cells for Erythropoietin-Induced Angiogenesis

M. Chopp, Zhenggang Zhang, Lei Wang, 2011 .

Sensitization of cerebral tissue in nude mice with photodynamic therapy induces ADAM17/TACE and promotes glioma cell invasion.

M. Chopp, Zhenggang Zhang, Hao Jiang, 2008, Cancer letters.

Inhibition of ADAM17 reduces hypoxia‐induced brain tumor cell invasiveness

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2007, Cancer science.

Combination Treatment With VELCADE and Low-Dose Tissue Plasminogen Activator Provides Potent Neuroprotection in Aged Rats After Embolic Focal Ischemia

M. Chopp, Zhenggang Zhang, Li Zhang, 2010, Stroke.

MiR‐133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome‐Enriched Extracellular Particles

M. Chopp, Zhenggang Zhang, Yi Li, 2013, Stem cells.

Intravenous Administration of Human Bone Marrow Stromal Cells Induces Angiogenesis in the Ischemic Boundary Zone After Stroke in Rats

Yi Li, Jieli Chen, Michael Chopp, 2003, Circulation research.

Long noncoding RNA mediates stroke‐induced neurogenesis

M. Chopp, Zhenggang Zhang, X. Liu, 2020, Stem cells.

The diabetic brain and cognition

K. Jellinger, M. Kamal, M. Chopp, 2017, Journal of Neural Transmission.

ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation

Michael Chopp, Feng Jiang, Xuguang Zheng, 2009, Cancer biology & therapy.

Thymosin beta 4 up‐regulates miR‐200a expression and induces differentiation and survival of rat brain progenitor cells

M. Chopp, Zhenggang Zhang, S. Vyas, 2016, Journal of neurochemistry.

Promoting brain remodeling to aid in stroke recovery.

M. Chopp, Zhenggang Zhang, 2015, Trends in molecular medicine.

MicroRNA Profiling in Subventricular Zone after Stroke: MiR-124a Regulates Proliferation of Neural Progenitor Cells through Notch Signaling Pathway

M. Chopp, Zhenggang Zhang, Li Zhang, 2011, PloS one.

MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse

M. Chopp, Zhenggang Zhang, Lei Wang, 2018, Molecular Neurobiology.

Function of neural stem cells in ischemic brain repair processes

M. Chopp, Zhenggang Zhang, RuiLan Zhang, 2016, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

MicroRNA‐21 protects neurons from ischemic death

M. Chopp, Zhenggang Zhang, Li Zhang, 2010, The FEBS journal.

Mesenchymal Stem Cell-Derived Exosomes Provide Neuroprotection and Improve Long-Term Neurologic Outcomes in a Swine Model of Traumatic Brain Injury and Hemorrhagic Shock.

Michael Chopp, Ye Xiong, Vahagn C Nikolian, 2019, Journal of neurotrauma.

Systemic administration of cell-free exosomes generated by human bone marrow derived mesenchymal stem cells cultured under 2D and 3D conditions improves functional recovery in rats after traumatic brain injury

M. Chopp, Zhenggang Zhang, Hongqi Xin, 2017, Neurochemistry International.

MicroRNA-214 enriched exosomes from human cerebral endothelial cells (hCEC) sensitize hepatocellular carcinoma to anti-cancer drugs

M. Chopp, Zhenggang Zhang, Yong Lu, 2021, Oncotarget.

Exosome‐Mediated Transfer of miR‐133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth

Yi Li, Michael Chopp, Yi Zhang, 2012, Stem cells.

Effects of Administration Route on Migration and Distribution of Neural Progenitor Cells Transplanted into Rats with Focal Cerebral Ischemia, an MRI Study

M. Chopp, J. Ewing, Q. Jiang, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

MiR-17-92 cluster-enriched exosomes derived from human bone marrow mesenchymal stromal cells improve tissue and functional recovery in rats after traumatic brain injury.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2021, Journal of neurotrauma.

Epigenetics in Stroke Recovery

M. Chopp, Zhenggang Zhang, H. Kassis, 2017, Genes.

MicroRNA-146a Promotes Oligodendrogenesis in Stroke

M. Chopp, Zhenggang Zhang, X. Liu, 2015, Molecular Neurobiology.

Identification of miRNomes associated with adult neurogenesis after stroke using Argonaute 2-based RNA sequencing

A. Levin, M. Chopp, Jiani Hu, 2017, RNA biology.

Cerebrolysin improves cognitive performance in rats after mild traumatic brain injury.

M. Chopp, T. Schallert, Zhenggang Zhang, 2015, Journal of neurosurgery.

Small extracellular vesicles ameliorate peripheral neuropathy and enhance chemotherapy of oxaliplatin on ovarian cancer

M. Chopp, Zhenggang Zhang, Lei Wang, 2021, Journal of extracellular vesicles.

Ischemic Cerebral Endothelial Cell–Derived Exosomes Promote Axonal Growth

M. Chopp, Zhenggang Zhang, Li Zhang, 2020, Stroke.

Extracellular vesicles from mesenchymal stem cells reduce microglial-mediated neuroinflammation after cortical injury in aged Rhesus monkeys

M. Medalla, S. Finklestein, M. Chopp, 2019, GeroScience.

Extracellular vesicles from mesenchymal stem cells reduce microglial-mediated neuroinflammation after cortical injury in aged Rhesus monkeys

M. Medalla, S. Finklestein, M. Chopp, 2019, GeroScience.

Temporal profile of microglial response following transient (2h) middle cerebral artery occlusion

Michael Chopp, M. Chopp, Zhenggang Zhang, 1997, Brain Research.

Diabetes Mellitus Impairs Cognitive Function in Middle-Aged Rats and Neurological Recovery in Middle-Aged Rats After Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2016, Stroke.

Stroke Transiently Increases Subventricular Zone Cell Division from Asymmetric to Symmetric and Increases Neuronal Differentiation in the Adult Rat

M. Chopp, Zhenggang Zhang, Mei Lu, 2004, The Journal of Neuroscience.

Class IIa histone deacetylases affect neuronal remodeling and functional outcome after stroke

M. Chopp, Zhenggang Zhang, Xianshuang Liu, 2016, Neurochemistry International.

Angiopoietin 2 Mediates the Differentiation and Migration of Neural Progenitor Cells in the Subventricular Zone after Stroke*

M. Chopp, Zhenggang Zhang, Mei Lu, 2009, The Journal of Biological Chemistry.

Patterns and Dynamics of Subventricular Zone Neuroblast Migration in the Ischemic Striatum of the Adult Mouse

M. Chopp, Zhenggang Zhang, B. Buller, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Gene Profiles and Electrophysiology of Doublecortin-Expressing Cells in the Subventricular Zone after Ischemic Stroke

M. Chopp, Zhenggang Zhang, X. Liu, 2009, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Linkage of cell cycle kinetics between embryonic and adult stroke models: An analytical approach

M. Chopp, Zhenggang Zhang, Mei Lu, 2007, Journal of Neuroscience Methods.

Stromal Cell-Derived Factor 1α Mediates Neural Progenitor Cell Motility after Focal Cerebral Ischemia

M. Chopp, Zhenggang Zhang, Li Zhang, 2006 .

Neurogenesis in the Adult Ischemic Brain: Generation, Migration, Survival, and Restorative Therapy

M. Chopp, Zhenggang Zhang, R. Zhang, 2005, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.

Activated Neural Stem Cells Contribute to Stroke-Induced Neurogenesis and Neuroblast Migration toward the Infarct Boundary in Adult Rats

Ying Wang, Michael Chopp, Lei Wang, 2004, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Stromal cell-derived factor 1alpha mediates neural progenitor cell motility after focal cerebral ischemia.

M. Chopp, Zhenggang Zhang, Li Zhang, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Exosomes derived from high‐glucose‐stimulated Schwann cells promote development of diabetic peripheral neuropathy

M. Chopp, Zhenggang Zhang, Lei Wang, 2018, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Bone Marrow-Derived Endothelial Progenitor Cells Participate in Cerebral Neovascularization After Focal Cerebral Ischemia in the Adult Mouse

Michael Chopp, Quan Jiang, M. Chopp, 2002, Circulation research.

Upregulation of neuronal nitric oxide synthase and mRNA, and selective sparing of nitric oxide synthase-containing neurons after local cerebral ischemia in rat

M. Chopp, H. Schmidt, U. Förstermann, 1994, Brain Research.

MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats

M. Chopp, Zhenggang Zhang, X. Liu, 2017, Stroke.

Chemokine ligand 2 (CCL2) induces migration and differentiation of subventricular zone cells after stroke

M. Chopp, Zhenggang Zhang, X. Liu, 2007, Journal of neuroscience research.

Postischemic (6-Hour) Treatment With Recombinant Human Tissue Plasminogen Activator and Proteasome Inhibitor PS-519 Reduces Infarction in a Rat Model of Embolic Focal Cerebral Ischemia

M. Chopp, P. Elliott, Zhenggang Zhang, 2001, Stroke.

A nitric oxide donor induces neurogenesis and reduces functional deficits after stroke in rats

M. Chopp, Zhenggang Zhang, Mei Lu, 2001, Annals of neurology.

Microvascular structure after embolic focal cerebral ischemia in the rat

M. Chopp, M. Khalighi, H. Soltanian-Zadeh, 2003, Brain Research.

Influence of Sex on Cognition and Peripheral Neurovascular Function in Diabetic Mice

M. Chopp, Zhenggang Zhang, X. Liu, 2018, Front. Neurosci..

Erratum: Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke (Annals of Neurology (2003) 53 (743-751))

M. Chopp, Zhenggang Zhang, Mei Lu, 2005 .

Statins induce angiogenesis, neurogenesis, and synaptogenesis after stroke

Yi Li, Jieli Chen, Michael Chopp, 2003, Annals of neurology.

Impairment of the glymphatic system after diabetes

Michael Chopp, Esmaeil Davoodi-Bojd, Maiken Nedergaard, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Distal Axonal Proteins and Their Related MiRNAs in Cultured Cortical Neurons

A. Levin, M. Chopp, Zhenggang Zhang, 2018, Molecular Neurobiology.

Extra-Cellular Vesicles: A Promising Approach for Translating Cell-Based Therapy

M. Chopp, Zhenggang Zhang, B. Buller, 2018 .

Erythropoietin improves histological and functional outcomes after traumatic brain injury in mice in the absence of the neural erythropoietin receptor.

M. Chopp, T. Schallert, Zhenggang Zhang, 2010, Journal of neurotrauma.

Tissue Plasminogen Activator and Plasminogen Activator Inhibitor 1 Contribute to Sonic Hedgehog-Induced In Vitro Cerebral Angiogenesis

M. Chopp, Zhenggang Zhang, Mei Lu, 2012, PloS one.

p53‐Immunoreactive Protein and p53 mRNA Expression After Transient Middle Cerebral Artery Occlusion in Rats

M. Chopp, Zhenggang Zhang, Yi Li, 1994, Stroke.

Cerebrolysin Reduces Astrogliosis and Axonal Injury and Enhances Neurogenesis in Rats After Closed Head Injury

M. Chopp, Zhenggang Zhang, Mei Lu, 2018, Neurorehabilitation and neural repair.

IRS 2 Insulin receptor substrate-2

K. Jellinger, M. Kamal, M. Chopp, 2017 .

Src deficiency or blockade of Src activity in mice provides cerebral protection following stroke

Michael Chopp, Quan Jiang, David A. Cheresh, 2001, Nature Medicine.

Dual-color fluorescence imaging in a nude mouse orthotopic glioma model

M. Chopp, Zhenggang Zhang, Xuguang Zheng, 2009, Journal of Neuroscience Methods.

Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury

M. Chopp, Zhenggang Zhang, B. Buller, 2019, Nature Reviews Neurology.

Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons

M. Chopp, Zhenggang Zhang, X. Liu, 2016, Molecular Neurobiology.

Exosomes in stroke pathogenesis and therapy.

M. Chopp, Zhenggang Zhang, 2016, The Journal of clinical investigation.

Combination Therapy with Antiangiogenic Treatment and Photodynamic Therapy for the Nude Mouse Bearing U87 Glioblastoma

M. Chopp, S. Kalkanis, Zhenggang Zhang, 2007, Photochemistry and photobiology.

Increased therapeutic efficacy with rt-PA and anti-CD18 antibody treatment of stroke in the rat

M Chopp, M. Chopp, Zhenggang Zhang, 1999, Neurology.

Early (1 h) administration of tissue plasminogen activator reduces infarct volume without increasing hemorrhagic transformation after focal cerebral embolization in rats

Michael Chopp, Rui Lan Zhang, George Divine, 1998, Journal of the Neurological Sciences.

Analysis of Combined Treatment of Embolic Stroke in Rat with r-tPA and a GPIIb/IIIa Inhibitor

M. Chopp, R. Knight, J. Ewing, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Augmented healing process in female mice with acute myocardial infarction.

Zhenggang Zhang, Quan He, Fangfei Wang, 2007, Gender medicine.

Extension of the Therapeutic Window for Recombinant Tissue Plasminogen Activator With Argatroban in a Rat Model of Embolic Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2001, Stroke.

Map‐ISODATA demarcates regional response to combination rt‐PA and 7E3 F(ab′)2 treatment of embolic stroke in the rat

Hamid Soltanian-Zadeh, Michael Chopp, Li Zhang, 2005, Journal of magnetic resonance imaging : JMRI.

Multipotent mesenchymal stromal cells decrease transforming growth factor β1 expression in microglia/macrophages and down-regulate plasminogen activator inhibitor 1 expression in astrocytes after stroke

M. Chopp, Zhenggang Zhang, Yi Li, 2013, Neuroscience Letters.

Lengthening the G1 Phase of Neural Progenitor Cells is Concurrent with An Increase of Symmetric Neuron Generating Division after Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The linkage of neural progenitor cell cycle profiles between embryonic and adult stroke models: Analytical approach II

M. Chopp, Zhenggang Zhang, Mei Lu, 2008, Journal of Neuroscience Methods.

Sildenafil Ameliorates Long Term Peripheral Neuropathy in Type II Diabetic Mice

M. Chopp, Zhenggang Zhang, Mei Lu, 2015, PloS one.

MicroRNA 146a locally mediates distal axonal growth of dorsal root ganglia neurons under high glucose and sildenafil conditions

M. Chopp, Zhenggang Zhang, Lei Wang, 2016, Neuroscience.

Secondary Release of Exosomes from Astrocytes Contributes to the Increase in Neural Plasticity and Improvement of Functional Recovery after Stroke in Rats Treated with Exosomes Harvested from MicroRNA 133b-Overexpressing Multipotent Mesenchymal Stromal Cells

M. Chopp, Zhenggang Zhang, Hongqi Xin, 2017, Cell transplantation.

The expression of P- and E-selectins in three models of middle cerebral artery occlusion

M. Chopp, Zhenggang Zhang, C. Powers, 1998, Brain Research.

Delayed (21 Days) Post Stroke Treatment With RPh201, a Botany-Derived Compound, Improves Neurological Functional Recovery in a Rat Model of Embolic Stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2020, Frontiers in Neuroscience.

Neurogenin 1 Mediates Erythropoietin Enhanced Differentiation of Adult Neural Progenitor Cells

M. Chopp, Zhenggang Zhang, Lei Wang, 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Nitric oxide changes in the rat brain after transient middle cerebral artery occlusion

M. Chopp, Zhenggang Zhang, T. Malinski, 1995, Journal of the Neurological Sciences.

M. Chopp, Q. Jiang, Zhenggang Zhang, 2022, Frontiers in Aging Neuroscience.

In vivo magnetic resonance imaging tracks adult neural progenitor cell targeting of brain tumor

Michael Chopp, Feng Jiang, Quan Jiang, 2004, NeuroImage.

Treatment of diabetic peripheral neuropathy with engineered mesenchymal stromal cell-derived exosomes enriched with microRNA-146a provide amplified therapeutic efficacy

M. Chopp, Zhenggang Zhang, X. Liu, 2021, Experimental Neurology.

Targeting nitric oxide in the subacute restorative treatment of ischemic stroke

M. Chopp, Zhenggang Zhang, R. Zhang, 2013, Expert opinion on investigational drugs.

Sildenafil Enhances Neurogenesis and Oligodendrogenesis in Ischemic Brain of Middle-Aged Mouse

M. Chopp, Zhenggang Zhang, Mei Lu, 2012, PloS one.

The Sonic Hedgehog Pathway Mediates Carbamylated Erythropoietin-enhanced Proliferation and Differentiation of Adult Neural Progenitor Cells*

M. Chopp, Zhenggang Zhang, M. Leist, 2007, Journal of Biological Chemistry.

MRI detects white matter reorganization after neural progenitor cell treatment of stroke

Lei Wang, Li Zhang, Quan Jiang, 2006, NeuroImage.

The Effect of Hypothermia on Transient Middle Cerebral Artery Occlusion in the Rat

M Chopp, M. Chopp, Zhenggang Zhang, 1992, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Investigation of neural progenitor cell induced angiogenesis after embolic stroke in rat using MRI

Lei Wang, Li Zhang, Quan Jiang, 2005, NeuroImage.

ABCA1/ApoE/HDL Pathway Mediates GW3965-Induced Neurorestoration After Stroke

M. Chopp, Zhenggang Zhang, Jieli Chen, 2017, Stroke.

Effects of a Selective CD11b/CD18 Antagonist and Recombinant Human Tissue Plasminogen Activator Treatment Alone and in Combination in a Rat Embolic Model of Stroke

Michael Chopp, Li Zhang, Michael Krams, 2003, Stroke.

Quantitative measurement of motor and somatosensory impairments after mild (30 min) and severe (2 h) transient middle cerebral artery occlusion in rats

Jieli Chen, Michael Chopp, Li Zhang, 2000, Journal of the Neurological Sciences.

Role of the glymphatic system in ageing and diabetes mellitus impaired cognitive function

M. Chopp, Q. Jiang, Zhenggang Zhang, 2019, Stroke and Vascular Neurology.

Endogenous Tissue Plasminogen Activator Mediates Bone Marrow Stromal Cell-Induced Neurite Remodeling After Stroke in Mice

M. Chopp, Zhenggang Zhang, Mei Lu, 2011, Stroke.

Quantitative Evaluation of BBB Permeability after Embolic Stroke in Rat Using MRI

M. Chopp, R. Knight, J. Ewing, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

MRI Identification of White Matter Reorganization Enhanced by Erythropoietin Treatment in a Rat Model of Focal Ischemia

Michael Chopp, Mei Lu, Quan Jiang, 2009, Stroke.

Identification of cerebral ischemic lesions in rat using eigenimage filtered magnetic resonance imaging

Hamid Soltanian-Zadeh, Michael Chopp, Donald J. Peck, 1999, Brain Research.

Tadalafil, a long-acting type 5 phosphodiesterase isoenzyme inhibitor, improves neurological functional recovery in a rat model of embolic stroke

M. Chopp, Zhenggang Zhang, Li Zhang, 2006, Brain Research.

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Augments Thrombolysis of tPA (Tissue-Type Plasminogen Activator) in Aged Rats After Stroke.

M. Chopp, Zhenggang Zhang, Li Zhang, 2019, Stroke.

First translational ‘Think Tank’ on cerebrovascular disease, cognitive impairment and dementia

Farzaneh A. Sorond, Geert Jan Biessels, Deborah Gustafson, 2016, Journal of Translational Medicine.

Gene profiles within the adult subventricular zone niche: proliferation, differentiation and migration of neural progenitor cells in the ischemic brain.

M. Chopp, Zhenggang Zhang, R. Zhang, 2007, Current molecular medicine.

Cerebral Endothelial Nitric Oxide Synthase Expression After Focal Cerebral Ischemia in Rats

M. Chopp, J. Pollock, Zhenggang Zhang, 1993, Stroke.

MRI evaluation of treatment of embolic stroke in rat with intra-arterial and intravenous rt-PA

M. Chopp, J. Ewing, Q. Jiang, 2004, Journal of the Neurological Sciences.

Multiparametric ISODATA analysis of embolic stroke and rt-PA intervention in rat

Hamid Soltanian-Zadeh, James R. Ewing, Michael Chopp, 2004, Journal of the Neurological Sciences.

Magnetic Resonance Imaging Characterization of Hemorrhagic Transformation of Embolic Stroke in the Rat

Michael Chopp, Li Zhang, Mei Lu, 2002, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

T1 and magnetization transfer at 7 Tesla in acute ischemic infarct in the rat

M Chopp, M. Chopp, J. Ewing, 1999, Magnetic resonance in medicine.

Postischemic treatment (2–4 h) with anti-CD11b and anti-CD18 monoclonal antibodies are neuroprotective after transient (2 h) focal cerebral ischemia in the rat

Michael Chopp, Rui Lan Zhang, M. Chopp, 1995, Brain Research.

Exosomes derived from bone marrow mesenchymal stromal cells promote remyelination and reduce neuroinflammation in the demyelinating central nervous system

M. Medalla, M. Chopp, D. Rosene, 2021, Experimental Neurology.

Extracellular vesicles derived from bone marrow mesenchymal stem cells enhance myelin maintenance after cortical injury in aged rhesus monkeys

M. Medalla, S. Finklestein, M. Chopp, 2020, Experimental Neurology.

Magnetic Resonance Imaging Investigation of Axonal Remodeling and Angiogenesis after Embolic Stroke in Sildenafil-Treated Rats

Michael Chopp, Li Zhang, Quan Jiang, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Ablation of the microRNA‐17‐92 cluster in neural stem cells diminishes adult hippocampal neurogenesis and cognitive function

M. Chopp, Zhenggang Zhang, X. Liu, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

, MD MRI of Stroke Recovery

M. Chopp, Q. Jiang, Zhenggang Zhang, 2009 .

Quantitative Evaluation of Microvascular Density after Stroke in Rats using MRI

Asamoah Bosomtwi, Michael Chopp, Li Zhang, 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Three-dimensional analysis of complex branching vessels in confocal microscopy images.

Ali Shahrokni, Ali Afzali-Kusha, Hamid Soltanian-Zadeh, 2005, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

Histone deacetylase expression in white matter oligodendrocytes after stroke

M. Chopp, Zhenggang Zhang, X. Liu, 2014, Neurochemistry International.

Ablation of Argonaute 2 in Schwann cells accelerates the progression of diabetic peripheral neuropathy

M. Chopp, Zhenggang Zhang, X. Liu, 2023, Glia.

Postischemic intracarotid treatment with TNK-tPA reduces infarct volume and improves neurological deficits in embolic stroke in the unanesthetized rat

M. Chopp, Q. Jiang, Zhenggang Zhang, 2000, Brain Research.

Effects of posttraumatic carbamylated erythropoietin therapy on reducing lesion volume and hippocampal cell loss, enhancing angiogenesis and neurogenesis, and improving functional outcome in rats following traumatic brain injury.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2011, Journal of neurosurgery.

Distribution of the 72‐kd Heat‐Shock Protein as a Function of Transient Focal Cerebral Ischemia in Rats

Michael Chopp, Yasuji Yoshida, Yi Li, 1992, Stroke.

Detection of BBB disruption and hemorrhage by Gd-DTPA enhanced MRI after embolic stroke in rat

M. Chopp, J. Ewing, Q. Jiang, 2006, Brain Research.

Early Prediction of Gross Hemorrhagic Transformation by Noncontrast Agent MRI Cluster Analysis After Embolic Stroke in Rat

M. Chopp, R. Knight, V. Nagesh, 2005, Stroke.

A Model of Mini-Embolic Stroke Offers Measurements of the Neurovascular Unit Response in the Living Mouse

W. Gan, M. Chopp, Q. Jiang, 2005, Stroke.

Epigenetic Mechanisms Underlying Adult Post Stroke Neurogenesis

M. Chopp, Zhenggang Zhang, Xianshuang Liu, 2020, International journal of molecular sciences.

MRI of stroke recovery.

Michael Chopp, Quan Jiang, M. Chopp, 2010, Stroke.

A Small Molecule Spinogenic Compound Enhances Functional Outcome and Dendritic Spine Plasticity in a Rat Model of Traumatic Brain Injury.

Christopher Rex, M. Chopp, V. Simmon, 2019, Journal of neurotrauma.

Magnetic resonance imaging and neurosphere therapy of stroke in rat

Michael Chopp, Lei Wang, Li Zhang, 2003, Annals of neurology.

Cerebral tissue repair and atrophy after embolic stroke in rat: A magnetic resonance imaging study of erythropoietin therapy

M. Chopp, J. Ewing, Q. Jiang, 2010, Journal of neuroscience research.

Stroke Induces Ependymal Cell Transformation into Radial Glia in the Subventricular Zone of the Adult Rodent Brain

M. Chopp, Zhenggang Zhang, X. Liu, 2007, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Diffusion- and perfusion-weighted NMR imaging study of middle cerebral artery thrombotic focal ischemia and rt-PA intervention in rat

M. Chopp, J. Ewing, G. Divine, 1998 .

Diffusion-, T2-, and Perfusion-Weighted Nuclear Magnetic Resonance Imaging of Middle Cerebral Artery Embolic Stroke and Recombinant Tissue Plasminogen Activator Intervention in the Rat

M Chopp, M. Chopp, J. Ewing, 1998, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Therapeutic Benefit of Extended Thymosin β4 Treatment Is Independent of Blood Glucose Level in Mice with Diabetic Peripheral Neuropathy

M. Chopp, Zhenggang Zhang, Lei Wang, 2015, Journal of diabetes research.

Activation of the PI3-K/Akt Pathway Mediates cGMP Enhanced-Neurogenesis in the Adult Progenitor Cells Derived from the Subventricular Zone

M. Chopp, Zhenggang Zhang, Lei Wang, 2005, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

ARL 17477, a Potent and Selective Neuronal NOS Inhibitor Decreases Infarct Volume after Transient Middle Cerebral Artery Occlusion in Rats

M. Chopp, Zhenggang Zhang, W. Shakespeare, 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Differential long noncoding RNA and messenger RNA expression profiling and functional network analysis in stroke-induced neurogenesis

Michael Chopp, Xinli Wang, Xian Shuang Liu, 2019, 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM).

Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline.

M. Chopp, Zhenggang Zhang, Li Zhang, 2017, Journal of neurosurgery.

Vascular endothelial growth factor and angiopoietins in focal cerebral ischemia.

M. Chopp, Zhenggang Zhang, 2002, Trends in cardiovascular medicine.

Cerebrolysin Ameliorates BBB Leakage and Microvascular Inflammation Induced by tPA and Fibrin

M. Chopp, Zhenggang Zhang, Li Zhang, 2019 .

Histological and functional outcomes after traumatic brain injury in mice null for the erythropoietin receptor in the central nervous system

M. Chopp, T. Schallert, Zhenggang Zhang, 2008, Brain Research.

Prospective, double blinded, comparative assessment of the pharmacological activity of Cerebrolysin and distinct peptide preparations for the treatment of embolic stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2019, Journal of the Neurological Sciences.

Distal Axonal Proteins and Their Related MiRNAs in Cultured Cortical Neurons

A. Levin, M. Chopp, Zhenggang Zhang, 2018, Molecular Neurobiology.

Multitargeted Effects of Statin-Enhanced Thrombolytic Therapy for Stroke With Recombinant Human Tissue-Type Plasminogen Activator in the Rat

M. Chopp, Q. Jiang, Zhenggang Zhang, 2005, Circulation.

Magnetic Resonance Imaging of Stroke in the Rat.

Michael Chopp, Li Zhang, Quan Jiang, 2014, Bo pu xue za zhi = Chinese journal of microwave & radio-frequency spectroscopy.

The temporal evolution of MRI tissue signatures after transient middle cerebral artery occlusion in rat

Michael Chopp, Quan Jiang, James R Ewing, 1997, Journal of the Neurological Sciences.

Stroke Induces Nuclear Shuttling of Histone Deacetylase 4

M. Chopp, Zhenggang Zhang, C. Roberts, 2015, Stroke.

Treatment of neurological injury with thymosin β4

M. Chopp, Zhenggang Zhang, Li Zhang, 2012, Annals of the New York Academy of Sciences.

Modeling glymphatic system of the brain using MRI

Li Zhang, Quan Jiang, Zheng Gang Zhang, 2019, NeuroImage.

Measurement of myeloperoxidase immunoreactive cells in ischemic brain after transient middle cerebral artery occlusion in the rat

M. Chopp, Zhenggang Zhang, 1997 .

Improvement in functional recovery with administration of Cerebrolysin after experimental closed head injury.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2013, Journal of neurosurgery.

3-D quantification and visualization of vascular structures from confocal microscopic images using skeletonization and voxel-coding

Ali Shahrokni, Hamid Soltanian-Zadeh, Reza Aghaeizadeh Zoroofi, 2005, Comput. Biol. Medicine.

MRI of combination treatment of embolic stroke in rat with rtPA and atorvastatin

M. Chopp, J. Ewing, Q. Jiang, 2006, Journal of Neurological Sciences.

Diffusion, perfusion, and T 2 magnetic resonance imaging of anti-intercellular adhesion molecule 1 antibody treatment of transient middle cerebral artery occlusion in rat

Michael Chopp, Quan Jiang, Rui Lan Zhang, 1998, Brain Research.

Thymosin β4 for the treatment of acute stroke in aged rats

M. Chopp, Zhenggang Zhang, Mei Lu, 2017, Neuroscience Letters.

PDE5 inhibitors promote recovery of peripheral neuropathy in diabetic mice

M. Chopp, Zhenggang Zhang, Lei Wang, 2017, Neural regeneration research.

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain.

M Chopp, K Davies, M. Chopp, 2000, The Journal of clinical investigation.

Mesenchymal Stem Cell-Derived Exosomes Provide Neuroprotection and Improve Long-Term Neurologic Outcomes in a Swine Model of Traumatic Brain Injury and Hemorrhagic Shock.

Aaron M Williams, M. Chopp, Zhenggang Zhang, 2019, Journal of neurotrauma.

Neuroprotective and neurorestorative effects of thymosin β4 treatment following experimental traumatic brain injury

M. Chopp, Zhenggang Zhang, A. Mahmood, 2012, Annals of the New York Academy of Sciences.

Thymosin β4 improves functional neurological outcome in a rat model of embolic stroke

M. Chopp, Zhenggang Zhang, Mei Lu, 2010, Neuroscience.

Angiopoietin-1 reduces cerebral blood vessel leakage and ischemic lesion volume after focal cerebral embolic ischemia in mice

M Chopp, M. Chopp, Zhenggang Zhang, 2002, Neuroscience.

A Model for Multiparametric MRI Tissue Characterization in Experimental Cerebral Ischemia With Histological Validation in Rat: Part 1

H Soltanian-Zadeh, R A Knight, M Chopp, 2001, Stroke.

Thymosin β4: a candidate for treatment of stroke?

M. Chopp, Zhenggang Zhang, Li Zhang, 2010 .

Neurological functional recovery after thymosin beta4 treatment in mice with experimental auto encephalomyelitis

M. Chopp, Zhenggang Zhang, Jing Zhang, 2009, Neuroscience.

Magnetic Resonance Imaging Indexes of Therapeutic Efficacy of Recombinant Tissue Plasminogen Activator Treatment of Rat at 1 and 4 Hours after Embolic Stroke

R A Knight, M Chopp, M. Chopp, 2000, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

Glymphatic transport is reduced in rats with spontaneous pituitary tumor

M. Chopp, Q. Jiang, Zhenggang Zhang, 2023, Frontiers in medicine.

Therapeutic role of microRNAs of small extracellular vesicles from human mesenchymal stromal/stem cells in the treatment of experimental traumatic brain injury.

M. Chopp, Zhenggang Zhang, A. Mahmood, 2022, Journal of neurotrauma.

Characterization of cerebral tissue by MRI map ISODATA in embolic stroke in rat

Hamid Soltanian-Zadeh, James R. Ewing, Michael Chopp, 2006, Brain Research.

MRI investigation of glymphatic responses to Gd‐DTPA infusion rates

Michael Chopp, Esmaeil Davoodi-Bojd, Li Zhang, 2018, Journal of neuroscience research.

Induction of DNA fragmentation after 10 to 120 minutes of focal cerebral ischemia in rats.

M. Chopp, Zhenggang Zhang, Yi Li, 1995, Stroke.

Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline.

M. Chopp, Zhenggang Zhang, Li Zhang, 2016, Journal of neurosurgery.

Stroke Induces Nuclear Shuttling of Histone Deacetylase 4

M. Chopp, Zhenggang Zhang, C. Roberts, 2015, Stroke.

Impairment of the glymphatic system after diabetes

M. Chopp, M. Nedergaard, Q. Jiang, 2017, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

The diabetic brain and cognition

K. Jellinger, M. Kamal, M. Chopp, 2017, Journal of Neural Transmission.

Effects of Administration Route on Migration and Distribution of Neural Progenitor Cells Transplanted into Rats with Focal Cerebral Ischemia, an MRI Study

M. Chopp, J. Ewing, Q. Jiang, 2010, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

MiR‐133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome‐Enriched Extracellular Particles

M. Chopp, Zhenggang Zhang, Yi Li, 2013, Stem cells.

An Activated Protein C Analog With Reduced Anticoagulant Activity Extends the Therapeutic Window of Tissue Plasminogen Activator for Ischemic Stroke in Rodents

M. Chopp, J. Griffin, Zhenggang Zhang, 2012, Stroke.

MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse

M. Chopp, Zhenggang Zhang, Lei Wang, 2018, Molecular Neurobiology.

Axonal Outgrowth and Dendritic Plasticity in the Cortical Peri-Infarct Area After Experimental Stroke

N. Lehman, M. Chopp, Zhenggang Zhang, 2012, Stroke.

Exosome‐Mediated Transfer of miR‐133b from Multipotent Mesenchymal Stromal Cells to Neural Cells Contributes to Neurite Outgrowth

M. Chopp, Zhenggang Zhang, Yi Li, 2012, Stem cells.

Angiopoietin-1/Tie2 signaling pathway contributes to the therapeutic effect of thymosin β4 on diabetic peripheral neuropathy

M. Chopp, Zhenggang Zhang, Mei Lu, 2019, Neuroscience Research.

Cerebral Blood Flow Changes during Cortical Spreading Depression are Not Altered by Inhibition of Nitric Oxide Synthesis

M. Moskowitz, M. Chopp, K. I. Maynard, 1994, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

M. Chopp, Zhenggang Zhang, Hongqi Xin, 2017, Neurochemistry International.

Longitudinal Magnetic Resonance Imaging of Sildenafil Treatment of Embolic Stroke in Aged Rats

Michael Chopp, Li Zhang, Mei Lu, 2011, Stroke.

Magnetization transfer MRI: Application to treatment of middle cerebral artery occlusion in rat

M Chopp, M. Chopp, J. Ewing, 2001, Journal of magnetic resonance imaging : JMRI.

Thymosin β4 for the treatment of acute stroke: neurorestorative or neuroprotective?

M. Chopp, Zhenggang Zhang, D. Morris, 2018, Expert opinion on biological therapy.

Thymosin beta4 promotes oligodendrogenesis in the demyelinating central nervous system

M. Chopp, Zhenggang Zhang, Mei Lu, 2016, Neurobiology of Disease.

Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery

Zhenggang Zhang, Zhongwu Liu, Yi Zhang, 2024, Neural regeneration research.

Anti‐adhesion molecule and nitric oxide protection strategies in ischemic stroke

M. Chopp, Zhenggang Zhang, Z. Zhang, 1996, Current opinion in neurology.