J. Contessa

发表

Molecular mechanisms of radiation-induced accelerated repopulation.

R. Schmidt-Ullrich, J. Contessa, P. Dent, 1999, Radiation oncology investigations.

Stress and Radiation-Induced Activation of Multiple Intracellular Signaling Pathways1

R. Schmidt-Ullrich, J. Contessa, P. Dent, 2003, Radiation research.

The prognostic value of extranodal extension in human papillomavirus‐associated oropharyngeal squamous cell carcinoma

J. Contessa, R. Decker, W. Yarbrough, 2017, Cancer.

Patterns of care and outcomes for use of concurrent chemoradiotherapy over radiotherapy alone for anaplastic gliomas.

J. Contessa, R. Bindra, James B. Yu, 2017, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Molecular Imaging of N-linked Glycosylation Suggests Glycan Biosynthesis Is a Novel Target for Cancer Therapy

B. Ross, H. Freeze, A. Rehemtulla, 2010, Clinical Cancer Research.

Angiotensin receptor blockade: a novel approach for symptomatic radiation necrosis after stereotactic radiosurgery

J. Olson, W. Curran, R. Abrams, 2017, Journal of Neuro-Oncology.

Demonstration of differential radiosensitivity based upon mutation profile in metastatic melanoma treated with stereotactic radiosurgery.

H. Kluger, J. Contessa, R. Bindra, 2016, Journal of radiosurgery and SBRT.

Aberrant Cellular Glycosylation May Increase the Ability of Influenza Viruses to Escape Host Immune Responses through Modification of the Viral Glycome

J. Contessa, K. Hartshorn, C. Goldsmith, 2022, mBio.

A contemporary dose selection algorithm for stereotactic radiosurgery in the treatment of brain metastases - An initial report.

J. Knisely, J. Contessa, R. Bindra, 2016, Journal of radiosurgery and SBRT.

Hypoxia-Guided Therapy for Human Papillomavirus-Associated Oropharynx Cancer.

J. Contessa, B. Burtness, B. Burtness, 2021, Journal of the National Cancer Institute.

Evaluation of quantitative modeling methods in whole-body, dynamic [11C]-erlotinib PET.

Yiyun Huang, N. Nabulsi, E. Morris, 2021, American journal of nuclear medicine and molecular imaging.

High-throughput screening identifies aclacinomycin as a radiosensitizer of EGFR-mutant non-small cell lung cancer.

A. Rehemtulla, J. Contessa, M. Lehrman, 2013, Translational oncology.

Initial SRS for Patients With 5 to 15 Brain Metastases: Results of a Multi-Institutional Experience.

J. Fiveash, J. Contessa, K. Watabe, 2018, International journal of radiation oncology, biology, physics.

Targeting STT3A‐oligosaccharyltransferase with NGI‐1 causes herpes simplex virus 1 dysfunction

J. Contessa, M. Lehrman, R. Gilmore, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

A Small-Molecule Oligosaccharyltransferase Inhibitor with Pan-flaviviral Activity.

J. Carette, J. Contessa, Karim Majzoub, 2017, Cell reports.

Editing N-Glycan Site Occupancy with Small-Molecule Oligosaccharyltransferase Inhibitors.

Jennifer E. Golden, J. Carette, J. Contessa, 2018, Cell chemical biology.

Role of excision repair cross‐complementation 1 expression as a prognostic marker for response to radiotherapy in early‐stage laryngeal cancer

J. Contessa, R. Decker, Hao Wu, 2013, Head & neck.

Results of a pilot/phase II study of gamma knife radiosurgery for brain metastases and implications for future prospective clinical trials

J. Contessa, R. Bindra, K. Roberts, 2019, Journal of Radiation Oncology.

The Ras / Rac 1 / Cdc 42 / SEK / JNK / c-Jun Cascade Is a Key Pathway by Which Agonists Stimulate DNA Synthesis in Primary Cultures of Rat Hepatocytes

L. Pirola, A. Abo, J. Contessa, 1998 .

Oligosaccharyltransferase Inhibition Overcomes Therapeutic Resistance to EGFR Tyrosine Kinase Inhibitors.

Abhijit A. Patel, Patricia Greninger, C. Benes, 2018, Cancer research.

STING Agonists in Head and Neck Squamous Cell Carcinoma

J. Contessa, T. Hayman, D. Wallington, 2022, Cancer journal.

Clinical and genomic factors associated with seizures in meningiomas.

Mark W. Youngblood, R. Fulbright, K. Mishra-Gorur, 2020, Journal of neurosurgery.

Impact of radiotherapy delay following biopsy for patients with unresected glioblastoma.

J. Contessa, R. Bindra, James B. Yu, 2022, Journal of neurosurgery.

RADI-31. MULTI-INSTITUTIONAL VALIDATION OF BRAIN METASTASIS VELOCITY, A RECENTLY DEFINED PREDICTOR OF OUTCOMES FOLLOWING STEREOTACTIC RADIOSURGERY

B. Pasche, M. Ahluwalia, R. Kotecha, 2017, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Comparison of Survival Outcomes Among Human Papillomavirus–Negative cT1-2 N1-2b Patients With Oropharyngeal Squamous Cell Cancer Treated With Upfront Surgery vs Definitive Chemoradiation Therapy: An Observational Study

J. Contessa, R. Decker, W. Yarbrough, 2017, JAMA oncology.

Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA)

P. Brown, M. Mehta, H. Shih, 2017, JAMA oncology.

Radiosensitization of malignant glioma cells through overexpression of dominant-negative epidermal growth factor receptor.

R. Schmidt-Ullrich, J. Contessa, P. Dent, 2001, Clinical cancer research : an official journal of the American Association for Cancer Research.

The translocon-associated protein (TRAP) complex regulates quality control of N-linked glycosylation during ER stress

J. Contessa, L. Wells, Peng Zhao, 2021, Science Advances.

Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing

H. Freeze, J. Contessa, L. Wells, 2019, Disease Models & Mechanisms.

Dominant negative EGFR-CD533 and inhibition of MAPK modify JNK1 activation and enhance radiation toxicity of human mammary carcinoma cells

J. Contessa, P. Dent, R. Mikkelsen, 1999, Oncogene.

EGFRvIII-mediated radioresistance through a strong cytoprotective response

J. Contessa, P. Dent, K. Valerie, 2003, Oncogene.

Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells

J. Contessa, P. Dent, R. Mikkelsen, 2002, Oncogene.

Extended Survival and Prognostic Factors for Patients With ALK-Rearranged Non-Small-Cell Lung Cancer and Brain Metastasis.

N. Yeh, B. Kavanagh, K. Beal, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Clinically relevant shifts in endogenous and exogenous mutational processes proximate to metastasis support local consolidative treatment in EGFR-driven non-small cell lung cancer

J. Townsend, D. Rimm, J. Contessa, 2021, medRxiv.

STING enhances cell death through regulation of reactive oxygen species and DNA damage

D. Rimm, J. Contessa, B. Burtness, 2021, Nature Communications.

UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer

N. Neamati, A. Rehemtulla, T. Lawrence, 2020, Translational oncology.

CDKN2A Copy Number Loss Is an Independent Prognostic Factor in HPV-Negative Head and Neck Squamous Cell Carcinoma

J. Townsend, J. Contessa, R. Bindra, 2018, Front. Oncol..

Mannose Phosphate Isomerase Regulates Fibroblast Growth Factor Receptor Family Signaling and Glioma Radiosensitivity

J. Contessa, Aurélie S. Cazet, Daniel C. Bennett, 2014, PloS one.

Premetastatic shifts of endogenous and exogenous mutational processes support consolidative therapy in EGFR-driven lung adenocarcinoma.

J. Townsend, J. Contessa, S. Aneja, 2021, Cancer letters.

A Clinical Model for Identifying Radiosensitive Tumor Genotypes in Non–Small Cell Lung Cancer

S. Gettinger, J. Contessa, R. Decker, 2013, Clinical Cancer Research.

Predictive Biomarkers and Personalized Medicine A Clinical Model for Identifying Radiosensitive Tumor Genotypes in Non – Small Cell Lung Cancer

S. Gettinger, J. Contessa, R. Decker, 2013 .

Oligosaccharyltransferase Inhibition Reduces Receptor Tyrosine Kinase Activation and Enhances Glioma Radiosensitivity

J. Contessa, W. Saltzman, M. Baro, 2018, Clinical Cancer Research.

Lung Cancer Brain Metastases

J. Contessa, S. Omay, V. Chiang, 2015 .

Management of Brain Metastases in Tyrosine Kinase Inhibitor-Naïve Epidermal Growth Factor Receptor-Mutant Non-Small-Cell Lung Cancer: A Retrospective Multi-Institutional Analysis.

S. Gettinger, A. Amini, B. Kavanagh, 2017, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Spatially resolved analysis of the T cell immune contexture in lung cancer-associated brain metastases

K. Schalper, H. Kluger, J. Contessa, 2021, Journal for ImmunoTherapy of Cancer.

Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.

J. Sarkaria, K. Camphausen, P. Choyke, 2018, The Lancet. Oncology.

Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation

J. Contessa, R. Mikkelsen, K. Valerie, 2005, Breast Cancer Research and Treatment.

Quantitative analysis of [11C]-erlotinib PET demonstrates specific binding for activating mutations of the EGFR kinase domain.

Ming-Qiang Zheng, Jenna M. Sullivan, Evan D Morris, 2013, Neoplasia.

Quantitative Analysis of ( 11 C)-Erlotinib PET Demonstrates Specific Binding for Activating Mutations of the EGFR

Evan D. Morris, Ming-Qiang Zheng, Jenna M. Sullivan, 2013 .

Oligosaccharyltransferase inhibition induces senescence in RTK-driven tumor cells.

Jennifer E. Golden, Lance Wells, Carol Khodier, 2016, Nature chemical biology.

Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells.

H. Freeze, A. Rehemtulla, T. Lawrence, 2008, Cancer research.

Epidermal growth factor receptor as a genetic therapy target for carcinoma cell radiosensitization.

R. Schmidt-Ullrich, J. Contessa, P. Dent, 2001, Journal of the National Cancer Institute.

Receptor Tyrosine Kinases as Targets for Enhancing Tumor Radiosensitivity

J. Contessa, T. Hayman, 2017 .

Defining an Intermediate-risk Group for Low-grade Glioma: A National Cancer Database Analysis

W. Curran, M. Mehta, J. Contessa, 2019, AntiCancer Research.

The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes.

L. Pirola, A. Abo, J. Contessa, 1998, Molecular biology of the cell.

Multicenter analysis of stereotactic radiosurgery for multiple brain metastases from EGFR and ALK driven non-small cell lung cancer.

D. Gao, J. Sheehan, Aileen B Chen, 2022, Lung cancer.

Multi-institutional competing risks analysis of distant brain failure and salvage patterns after upfront radiosurgery without whole brain radiotherapy for brain metastasis

M. Ahluwalia, R. Kotecha, J. Fiveash, 2018, Annals of oncology : official journal of the European Society for Medical Oncology.

Prediction of new brain metastases after radiosurgery: validation and analysis of performance of a multi-institutional nomogram

A. Peiffer, M. Ahluwalia, R. Kotecha, 2017, Journal of Neuro-Oncology.

Differences in patterns of care and outcomes between grade II and grade III molecularly defined 1p19q co-deleted gliomas

J. Huse, E. Sulman, J. Contessa, 2018, Clinical and translational radiation oncology.

Practice Patterns Related to Mitigation of Neurocognitive Decline in Patients Receiving Whole Brain Radiation Therapy

J. Contessa, R. Bindra, James B. Yu, 2022, Advances in radiation oncology.

Practice Patterns Related to Mitigation of Neurocognitive Decline in Patients Receiving Whole-Brain Radiation Therapy.

J. Contessa, R. Bindra, V. Jairam, 2021, International journal of radiation oncology, biology, physics.

Radiation Therapy for Low Grade Meningiomas

J. Contessa, G. Peters, 2020 .

MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo

J. Contessa, Aurélie S. Cazet, Daniel C. Bennett, 2018, Glycoconjugate Journal.

CDKN2A copy number loss in HPV- and HPV+ head and neck cancer to indicate poor prognosis: An integrated genomic and clinical TCGA analysis.

J. Townsend, J. Contessa, R. Bindra, 2017 .

The inducible expression of dominant-negative epidermal growth factor receptor-CD533 results in radiosensitization of human mammary carcinoma cells.

R. Schmidt-Ullrich, J. Contessa, P. Dent, 1999, Clinical cancer research : an official journal of the American Association for Cancer Research.

Upfront surgery versus definitive chemoradiotherapy in patients with human Papillomavirus-associated oropharyngeal squamous cell cancer.

J. Contessa, R. Decker, W. Yarbrough, 2018, Oral oncology.

A multi species evaluation of the radiation dosimetry of [11C]erlotinib, the radiolabeled analog of a clinically utilized tyrosine kinase inhibitor.

Yiyun Huang, A. Lammertsma, N. Nabulsi, 2017, Nuclear medicine and biology.

Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation

B. Kavanagh, J. Contessa, P. Dent, 1997, Oncogene.

Molecular imaging of epidermal growth factor receptor kinase activity.

B. Ross, A. Rehemtulla, J. Contessa, 2011, Analytical biochemistry.

The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases.

P. Brown, M. Mehta, H. Shih, 2016, International journal of radiation oncology, biology, physics.

Radiotherapy for pancreatic neuroendocrine tumors.

K. Griffith, T. Lawrence, J. Contessa, 2009, International journal of radiation oncology, biology, physics.

ERBB receptor tyrosine kinases and cellular radiation responses

J. Contessa, P. Lin, G. Amorino, 2003, Oncogene.

ErbB receptor tyrosine kinase network inhibition radiosensitizes carcinoma cells.

J. Contessa, K. Valerie, P. Lin, 2006, International journal of radiation oncology, biology, physics.

Anti‐erbB receptor strategy as a gene therapeutic intervention to improve radiotherapy in malignant human tumours

R. Schmidt-Ullrich, J. Contessa, K. Valerie, 2003, International journal of radiation biology.

Adenovirus-mediated overexpression of dominant negative epidermal growth factor receptor-CD533 as a gene therapeutic approach radiosensitizes human carcinoma and malignant glioma cells.

R. Schmidt-Ullrich, J. Contessa, K. Valerie, 2001, International journal of radiation oncology, biology, physics.

Reply to M.S. Copur et al and to M.C. Chamberlain.

J. Contessa, K. Johung, V. Chiang, 2016, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Revoking the Privilege: Targeting HER2 in the Central Nervous System

D. Hamstra, J. Contessa, 2008, Molecular Pharmacology.

Neuregulin Signaling Is a Mechanism of Therapeutic Resistance in Head and Neck Squamous Cell Carcinoma

J. Contessa, M. Lemmon, B. Burtness, 2019, Molecular Cancer Therapeutics.

Salvage Stereotactic Radiosurgery is Associated with Improved Overall Survival Compared to Whole Brain Radiation in the Setting of Progressive Brain Metastases

B. Pasche, M. Ahluwalia, S. Tatter, 2018, International Journal of Radiation Oncology*Biology*Physics.

MPDU1 regulates CEACAM1 and cell adhesion in vitro and in vivo

J. Contessa, Aurélie S. Cazet, Daniel C. Bennett, 2018, Glycoconjugate Journal.

Selective inhibition of N-linked glycosylation impairs receptor tyrosine kinase processing

H. Freeze, J. Contessa, L. Wells, 2019, Disease Models & Mechanisms.

Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology.

J. Sarkaria, K. Camphausen, P. Choyke, 2018, The Lancet. Oncology.

Lung Cancer Brain Metastases

J. Contessa, S. Omay, V. Chiang, 2015, Cancer journal.

Meningioma

J. Contessa, Gabrielle W. Peters, 2019, Pocket Guide to Radiation Oncology.

Angiotensin receptor blockade: a novel approach for symptomatic radiation necrosis after stereotactic radiosurgery

J. Olson, W. Curran, R. Abrams, 2017, Journal of Neuro-Oncology.

Signal recognition particle receptor-β (SR-β) coordinates cotranslational N-glycosylation

J. Contessa, M. Lehrman, R. Gilmore, 2023, Science advances.

Multi-institutional validation of brain metastasis velocity, a recently defined predictor of outcomes following stereotactic radiosurgery.

B. Pasche, M. Ahluwalia, R. Kotecha, 2020, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Editing N-Glycan Site Occupancy with Small MoleculeOligosaccharyltransferase (OST) Inhibitors

J. Carette, J. Contessa, C. Marceau, 2019 .

Prostaglandin-Induced Activation of Nociceptive Neurons via Direct Interaction with Transient Receptor Potential A1 (TRPA1)

E. Mazzon, D. Hamstra, J. Contessa, 2008, Molecular Pharmacology.