A. Cooper

发表

α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

S. Lindquist, A. Gitler, A. Cashikar, 2006, Science.

The central role of noncoding RNA in the brain.

A. Cooper, Boris Guennewig, 2014, International review of neurobiology.

Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases

T. Stevens, A. Cooper, 1996, The Journal of cell biology.

Not All hERG Pore Domain Mutations Have a Severe Phenotype: G584S Has an Inactivation Gating Defect with Mild Phenotype Compared to G572S, Which Has a Dominant Negative Trafficking Defect and a Severe Phenotype

Jamie I Vandenberg, Adam P Hill, Anthony Varghese, 2009, Journal of cardiovascular electrophysiology.

Common Variants Coregulate Expression of GBA and Modifier Genes to Delay Parkinson's Disease Onset

T. Anderson, W. Schierding, A. Cooper, 2020, Movement disorders : official journal of the Movement Disorder Society.

A transcription regulatory network within the ACE2 locus may promote a pro-viral environment for SARS-CoV-2 by modulating expression of host factors

N. Karnani, W. Schierding, A. Cooper, 2020, bioRxiv.

Yeast Kex1p is a Golgi-associated membrane protein: deletions in a cytoplasmic targeting domain result in mislocalization to the vacuolar membrane

H. Bussey, A. Cooper, Howard Bussey, 1992, The Journal of cell biology.

Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death.

A. Cooper, Cole M. Haynes, Eric A Titus, 2004, Molecular cell.

An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport

A. Cooper, Cole M. Haynes, Sabrina R. Caldwell, 2002, The Journal of cell biology.

VPS27 controls vacuolar and endocytic traffic through a prevacuolar compartment in Saccharomyces cerevisiae

T. Stevens, A. Cooper, H. Yang, 1995, The Journal of cell biology.

Yeast KEX1 protease cleaves a prohormone processing intermediate in mammalian cells.

H. Bussey, A. Cooper, L. Thomas, 1990, The Journal of biological chemistry.

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.

G. Halliday, A. Cooper, E. Sidransky, 2014, Brain : a journal of neurology.

ATP13A2 (PARK9) protein levels are reduced in brain tissue of cases with Lewy bodies

G. Halliday, A. Cooper, Louise Cottle, 2013, Acta neuropathologica communications.

Lysosomal‐associated membrane protein 2 isoforms are differentially affected in early Parkinson's disease

G. Halliday, A. Cooper, B. Garner, 2015, Movement disorders : official journal of the Movement Disorder Society.

Establishing gene regulatory networks from Parkinson’s disease risk loci

W. Schierding, A. Cooper, J. O'Sullivan, 2021, bioRxiv.

Degradation of Endoplasmic Reticulum (ER) Quality Control Substrates Requires Transport between the ER and Golgi*

A. Cooper, K. Hill, Sabrina R. Caldwell, 2001, The Journal of Biological Chemistry.

Defining early changes in Alzheimer’s disease from RNA sequencing of brain regions differentially affected by pathology

J. Kril, G. Halliday, A. Cooper, 2021, Scientific Reports.

Enhancers active in dopamine neurons are a primary link between genetic variation and neuropsychiatric disease

Tao Wang, Yavor Hadzhiev, Ferenc Müller, 2018, Nature Neuroscience.

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models

Joshua A. Kritzer, Ernest Fraenkel, Susan Lindquist, 2010, Disease Models & Mechanisms.

Regulation of mitochondrial metabolism in murine skeletal muscle by the medium‐chain fatty acid receptor Gpr84

N. Turner, G. Cooney, A. Cooper, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

ERADicate ER stress or die trying.

A. Cooper, Margaret M Kincaid, 2007, Antioxidants & redox signaling.

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

S. Lindquist, A. Gitler, A. Cooper, 2009, Nature Genetics.

Parkinson's disease-linked human PARK9/ATP13A2 maintains zinc homeostasis and promotes α-Synuclein externalization via exosomes.

P. A. Lay, A. Cooper, K. Hill, 2014, Human molecular genetics.

Protein splicing: self-splicing of genetically mobile elements at the protein level.

T. Stevens, A. Cooper, A A Cooper, 1995, Trends in biochemical sciences.

The Role of the Parkinson's Disease Gene PARK9 in Essential Cellular Pathways and the Manganese Homeostasis Network in Yeast

X. Fang, A. Gitler, A. Cooper, 2012, PloS one.

Misfolded proteins traffic from the endoplasmic reticulum (ER) due to ER export signals.

A. Cooper, Margaret M Kincaid, 2006, Molecular biology of the cell.

Degradation of unassembled Vph1p reveals novel aspects of the yeast ER quality control system

A. Cooper, K. Hill, 2000, The EMBO journal.

The NG domain of the prokaryotic signal recognition particle receptor, FtsY, is fully functional when fused to an unrelated integral membrane polypeptide.

A. Cooper, A. Seluanov, A. Zelazny, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Single Molecule Fingerprinting Reveals Different Amplification Properties of α-Synuclein Oligomers and Preformed Fibrils in Seeding Assay

A. Cooper, K. Hill, Y. Gambin, 2021, bioRxiv.

Protein splicing of the yeast TFP1 intervening protein sequence: a model for self‐excision.

T. Stevens, A. Cooper, M A Lindorfer, 1993, The EMBO journal.

αSynuclein and Mitochondrial Dysfunction: A Pathogenic Partnership in Parkinson's Disease?

A. Cooper, Charmaine Lang, David S. W. Protter, 2012, Parkinson's disease.

Pathogenic effects of novel mutations in the P‐type ATPase ATP13A2 (PARK9) causing Kufor‐Rakeb syndrome, a form of early‐onset parkinsonism

D. Krainc, A. Mackay-Sim, A. Cooper, 2011, Human mutation.

Intronic Haplotypes in GBA Modify Age at Diagnosis of Parkinson's: Replication in a Subgroup

A. Cooper, J. O'Sullivan, G. Groeneveld, 2021, Movement disorders : official journal of the Movement Disorder Society.

Characterization of the yeast KEX1 gene product: a carboxypeptidase involved in processing secreted precursor proteins

H. Bussey, A. Cooper, Antony A. Cooper, 1989, Molecular and cellular biology.

Degradation of unassembled Vph 1 p reveals novel aspects of the yeast ER quality control system elevated levels of mevalonate and its metabolites

A. Cooper, K. Hill, 2013 .

Reduced glucocerebrosidase is associated with increased α-synuclein in sporadic Parkinson's disease.

G. Halliday, A. Cooper, E. Sidransky, 2014, Brain : a journal of neurology.

α-Synuclein is part of a diverse and highly conserved interaction network that includes PARK9 and manganese toxicity

S. Lindquist, A. Gitler, A. Cooper, 2009, Nature Genetics.

Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson’s disease models

Joshua A. Kritzer, E. Fraenkel, S. Lindquist, 2010, Disease Models & Mechanisms.

Protein splicing: Excision of intervening sequences at the protein level

A. Cooper, To M. H. Stevens, 1993, BioEssays : news and reviews in molecular, cellular and developmental biology.