C. Toseland

发表

AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data

Channa K. Hattotuwagama, Shelley L. Hemsley, D. Flower, 2005, Immunome research.

Fluorescent labeling and modification of proteins

Christopher P. Toseland, C. Toseland, 2013, Journal of chemical biology.

Benchmarking pKa prediction

D. Moss, D. Flower, M. Davies, 2006, BMC Biochemistry.

Using databases and data mining in vaccinology

Channa K. Hattotuwagama, D. Flower, I. Doytchinova, 2007, Expert opinion on drug discovery.

PPD v1.0—an integrated, web-accessible database of experimentally determined protein pKa values

Matthew N. Davies, Christopher P. Toseland, Darren R. Flower, 2005, Nucleic Acids Res..

Toward Prediction of Class II Mouse Major Histocompatibility Complex Peptide Binding Affinity: in Silico Bioinformatic Evaluation Using Partial Least Squares, a Robust Multivariate Statistical Technique

Channa K. Hattotuwagama, Pingping Guan, Debra J. Taylor, 2006, J. Chem. Inf. Model..

Nuclear myosin VI regulates the spatial organization of mammalian transcription initiation

C. Toseland, M. Martin-Fernandez, J. Gebhardt, 2020, bioRxiv.

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

B. Oh, C. Toseland, S. Gruber, 2015, eLife.

The ATPase cycle of PcrA helicase and its coupling to translocation on DNA.

C. Toseland, M. Webb, M. M. Martínez-Senac, 2009, Journal of molecular biology.

Competition between two high- and low-affinity protein-binding sites in myosin VI controls its cellular function

C. Toseland, M. Martin-Fernandez, Lin Wang, 2019, The Journal of Biological Chemistry.

Binding partner regulation of Myosin VI: Loss of tumour-suppressor Dab2 leads to enhanced activity of nuclear myosin

C. Toseland, M. Martin-Fernandez, Lin Wang, 2019 .

A reagentless biosensor for mRNA: a new tool to study transcription

C. Toseland, Yukti Hari-Gupta, A. Cook, 2017, bioRxiv.

DSD – An integrated, web-accessible database of Dehydrogenase Enzyme Stereospecificities

Christopher P. Toseland, Darren R. Flower, Helen M. McSparron, 2005, BMC Bioinformatics.

Molecular Basis for SMC Rod Formation and Its Dissolution upon DNA Binding

Nam Ki Lee, B. Oh, C. Toseland, 2015, Molecular cell.

Nuclear myosins – roles for molecular transporters and anchors

C. Toseland, Rosemarie E. Gough, Alexander W. Cook, 2020, Journal of Cell Science.

The roles of nuclear myosin in the DNA damage response.

C. Toseland, Alexander W. Cook, 2020, Journal of biochemistry.

Autophagy receptor NDP52 alters DNA conformation to modulate RNA polymerase II transcription

C. Toseland, M. Martin-Fernandez, Alice L. B. Pyne, 2022, bioRxiv.

Myosin VI moves on nuclear actin filaments and supports long-range chromatin rearrangements

C. Toseland, J. Hettich, J. Gebhardt, 2020, bioRxiv.

Monomeric PcrA helicase processively unwinds plasmid lengths of DNA in the presence of the initiator protein RepD

C. Toseland, M. Dillingham, G. Mashanov, 2013, Nucleic acids research.

ATPase Cycle and DNA Unwinding Kinetics of RecG Helicase

C. Toseland, M. Webb, Benjamin Powell, 2012, PloS one.

Crystal structure of Hop2–Mnd1 and mechanistic insights into its role in meiotic recombination

Christopher P. Toseland, Matteo Dal Peraro, Byung-Ha Oh, 2015, Nucleic acids research.

Visualizing helicases unwinding DNA at the single molecule level

C. Toseland, M. Wallace, M. Dillingham, 2010, Nucleic acids research.

Fluorescence and labelling: how to choose and what to do.

C. Toseland, N. Fili, Natalia Fili, 2014, Experientia supplementum.

Fluorescent Methods for Molecular Motors

C. Toseland, N. Fili, Natalia Fili, 2014, Experientia Supplementum.

Rapid reaction kinetic techniques.

C. Toseland, M. Geeves, 2014, Experientia supplementum.

ATPase Mechanism of the 5′-3′ DNA Helicase, RecD2

C. Toseland, M. Webb, 2013, The Journal of Biological Chemistry.

The mechanical response of talin

Jie Yan, Benjamin T Goult, Peiwen Cong, 2016, Nature Communications.

A Targeted and Tuneable DNA Damage Tool Using CRISPR/Cas9

C. Toseland, M. Martin-Fernandez, Lin Wang, 2021, bioRxiv.

Atomic Force Microscopy micro-rheology reveals large structural inhomogeneities in single cell-nuclei

C. Toseland, I. Schaap, N. Fili, 2017, Scientific Reports.

Regulation of Nuclear Mechanics and the Impact on DNA Damage

C. Toseland, Ália dos Santos, 2021, International journal of molecular sciences.

A survey of new PIs in the UK

C. Toseland, S. Acton, A. Bell, 2019, eLife.

DNA damage alters nuclear mechanics through chromatin reorganization

F. Rehfeldt, C. Toseland, M. Martin-Fernandez, 2020, bioRxiv.

Application of the SSB biosensor to study in vitro transcription

C. Toseland, Yukti Hari-Gupta, Alexander W. Cook, 2018, Biochemical and biophysical research communications.

Fluorescence tools to measure helicase activity in real time.

C. Toseland, M. Webb, 2010, Methods.

Unconventional Myosins: How Regulation Meets Function

C. Toseland, N. Fili, Natalia Fili, 2019, International journal of molecular sciences.

Myosin in chromosome organisation and gene expression

C. Toseland, Isabel W Shahid-Fuente, 2023, Biochemical Society transactions.

Myosin VI regulates the spatial organisation of mammalian transcription initiation

C. Toseland, M. Martin-Fernandez, J. Gebhardt, 2022, Nature Communications.

Binding partners regulate unfolding of myosin VI to activate the molecular motor

C. Toseland, M. Martin-Fernandez, T. Chew, 2020, bioRxiv.

NDP52 activates nuclear myosin VI to enhance RNA polymerase II transcription

C. Toseland, S. Ameer-Beg, M. Parsons, 2017, Nature Communications.

Empirical, AI, and QSAR Approaches to Peptide-MHC Binding Prediction

Channa K. Hattotuwagama, Pingping Guan, Matthew N. Davies, 2007 .

High throughput mechanobiology: Force modulation of ensemble biochemical and cell-based assays

C. Toseland, D. S. Pearson, N. Fili, 2020, bioRxiv.

3D environment modulates persistent lamin distribution and the biomechanical signature of the nucleus

C. Toseland, F. Monroy, Lin Wang, 2023, bioRxiv.

Alpha helical trans-membrane proteins: Enhanced prediction using a Bayesian approach

T. Attwood, D. Flower, C. Toseland, 2006, Bioinformation.

Beta barrel trans-membrane proteins: Enhanced prediction using a Bayesian approach

Darren R Flower, Teresa K Attwood, Paul D Taylor, 2006, Bioinformation.

A predictor of membrane class: Discriminating α-helical and β-barrel membrane proteins from non-membranous proteins

T. Attwood, D. Flower, C. Toseland, 2006, Bioinformation.

TATPred: a Bayesian method for the identification of twin arginine translocation pathway signal sequences

Darren R Flower, Teresa K Attwood, Paul D Taylor, 2006, Bioinformation.

LIPPRED: A web server for accurate prediction of lipoprotein signal sequences and cleavage sites

Darren R Flower, Teresa K Attwood, Paul D Taylor, 2006, Bioinformation.

Cloning, Expression, and Characterization of a Novel Molecular Motor, Leishmania Myosin-XXI*

C. Veigel, C. Toseland, C. Batters, 2012, The Journal of Biological Chemistry.

Direct Observation of the Myosin Power Stroke and its Reversal

J. Sellers, C. Veigel, C. Toseland, 2011 .

Using databases and data mining in vaccinology

Channa K. Hattotuwagama, D. Flower, I. Doytchinova, 2007, Expert opinion on drug discovery.

Fluorescence to study the ATPase mechanism of motor proteins.

C. Toseland, 2014, Experientia supplementum.

A single-molecule approach to visualize the unwinding activity of DNA helicases.

C. Toseland, M. Dillingham, J. Molloy, 2011, Methods in molecular biology.