Lufen Chang

发表

Mammalian MAP kinase signalling cascades

M. Karin, Lufen Chang, 2001, Nature.

Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis.

M. Karin, Lufen Chang, G. Firestein, 2002, Arthritis and rheumatism.

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance.

M. Karin, Lufen Chang, G. Hotamisligil, 2006, Proceedings of the National Academy of Sciences of the United States of America.

ITCH nuclear translocation and H1.2 polyubiquitination negatively regulate the DNA damage response

G. Peng, Lufen Chang, B. Zhou, 2018, Nucleic acids research.

IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha.

M. Karin, Lufen Chang, Zhi-wei Li, 2003, Immunity.

Identification of common variant alleles of the human guanosine monophosphate reductase gene

Lufen Chang, A. Yoshida, T. Kondoh, 1991, Human Genetics.

Chromosomal instability triggered by Rrm2b loss leads to IL-6 secretion and plasmacytic neoplasms.

Y. Yen, Lufen Chang, R. Guo, 2013, Cell reports.

A central role for JNK in obesity and insulin resistance

Michael Karin, M. Karin, Lufen Chang, 2002, Nature.

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

M. Karin, Lufen Chang, Yun-Cai Liu, 2006, Cell.

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

M. Karin, Lufen Chang, Zhi-wei Li, 2003 .

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Michael Karin, M. Karin, Lufen Chang, 2005, Cell.

c-Jun N-terminal kinase activation is required for the inhibition of neovascularization by thrombospondin-1

M. Karin, O. Volpert, N. Bouck, 2001, Oncogene.

Essential Roles of Receptor-Interacting Protein and TRAF2 in Oxidative Stress-Induced Cell Death

M. Karin, T. Jin, Lufen Chang, 2004, Molecular and Cellular Biology.

Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2

E. Wagner, K. Hochedlinger, M. Karin, 1999, Mechanisms of Development.

JNK1 is required for maintenance of neuronal microtubules and controls phosphorylation of microtubule-associated proteins.

Mark Ellisman, L. Goldstein, M. Karin, 2003, Developmental cell.

Activity of the Distal Positive Element of the Peripherin Gene Is Dependent on Proteins Binding to an Ets-like Recognition Site and a Novel Inverted Repeat Site (*)

Lufen Chang, M. Thompson, 1996, The Journal of Biological Chemistry.

RRM2B Suppresses Activation of the Oxidative Stress Pathway and is Up-regulated by P53 During Senescence

Lijun Xue, Y. Yen, P. Chu, 2012, Scientific Reports.

Canonical nuclear factor κB pathway links tumorigenesis of synchronous mantle-cell lymphoma, clear-cell renal-cell carcinoma, and GI stromal tumor.

Yate-Ching Yuan, Y. Yen, D. Ann, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

MicroRNA‐657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin‐like enhancer protein 1 through nuclear factor kappa B pathways

Y. Yen, Lixin Yang, Xiyong Liu, 2013, Hepatology.

p53R2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest

Y. Yen, Xiyong Liu, D. Ann, 2011, Molecular Cancer Therapeutics.

1 p 53 R 2 inhibits the proliferation of human cancer cells in association with cell cycle arrest

Y. Yen, Xiyong Liu, D. Ann, 2011 .

Therapeutic Discovery p 53 R 2 Inhibits the Proliferation of Human Cancer Cells in Association with Cell-Cycle Arrest

Y. Yen, Xiyong Liu, D. Ann, 2011 .

ATM-mediated serine 72 phosphorylation stabilizes ribonucleotide reductase small subunit p53R2 protein against MDM2 to DNA damage

Y. Yen, Xiyong Liu, Lufen Chang, 2008, Proceedings of the National Academy of Sciences.

Loss of hepatic NF-kappa B activity enhances chemical hepatocarcinogenesis through sustained c-Jun N-terminal kinase 1 activation.

M. Karin, T. Sakurai, Lufen Chang, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Triptolide-Assisted Phosphorylation of p53 Suppresses Inflammation-Induced NF-κB Survival Pathways in Cancer Cells

Lufen Chang, Xufeng Chen, B. Shen, 2017, Molecular and Cellular Biology.

Genomic structure and expression of human guanosine monophosphate reductase

Lufen Chang, A. Yoshida, T. Kondoh, 1991, Human Genetics.

JNK2 and IKKbeta are required for activating the innate response to viral infection.

M. Karin, Lufen Chang, Zhi-wei Li, 1999, Immunity.

c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis.

M. Karin, A. Manning, Lufen Chang, 2001, The Journal of clinical investigation.

MicroRNA‐657 promotes tumorigenesis in hepatocellular carcinoma by targeting transducin‐like enhancer protein 1 through nuclear factor kappa B pathways

Y. Yen, Lixin Yang, Xiyong Liu, 2013, Hepatology.

Canonical nuclear factor κB pathway links tumorigenesis of synchronous mantle-cell lymphoma, clear-cell renal-cell carcinoma, and GI stromal tumor.

Yate-Ching Yuan, Y. Yen, D. Ann, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.