H. Geuze

发表

Synaptic assembly of the brain in the absence of neurotransmitter secretion.

T. Südhof, R. Hammer, M. Missler, 2000, Science.

The Biogenesis and Functions of Exosomes

Graça Raposo, Willem Stoorvogel, Hans J. Geuze, 2002, Traffic.

Proteomic and Biochemical Analyses of Human B Cell-derived Exosomes

J. Slot, W. Möbius, H. Geuze, 2003, The Journal of Biological Chemistry.

Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT).

P. Cresswell, H. Geuze, H. Geuze, 2000, Proceedings of the National Academy of Sciences of the United States of America.

MHC Class II Compartments in Human Dendritic Cells Undergo Profound Structural Changes Upon Activation

H. Geuze, S. Lebecque, M. Kleijmeer, 2002, Traffic.

Human resident langerhans cells display a lysosomal compartment enriched in MHC class II.

H. Geuze, V. Oorschot, M. Kleijmeer, 1994, The Journal of investigative dermatology.

The cytoplasmic tail of mouse hepatitis virus M protein is essential but not sufficient for its retention in the Golgi complex.

H. Geuze, Marian C. Horzinek, P. Rottier, 1994, The Journal of biological chemistry.

Coronavirus M proteins accumulate in the Golgi complex beyond the site of virion budding

H. Geuze, Marian C. Horzinek, P. Rottier, 1994, Journal of virology.

Mannose 6–Phosphate Receptors Are Sorted from Immature Secretory Granules via Adaptor Protein AP-1, Clathrin, and Syntaxin 6–positive Vesicles

P. Arvan, H. Geuze, J. Klumperman, 1998, The Journal of cell biology.

Cooperation of GGAs and AP-1 in Packaging MPRs at the Trans-Golgi Network

H. Geuze, S. Kornfeld, P. Ghosh, 2002, Science.

The FcγRIa (CD64) Ligand Binding Chain Triggers Major Histocompatibility Complex Class II Antigen Presentation Independently of Its Associated FcR γ-Chain

H. Geuze, M. Kleijmeer, T. Keler, 1999 .

Transport from late endosomes to lysosomes, but not sorting of integral membrane proteins in endosomes, depends on the vacuolar proton pump

H. Geuze, W. Stoorvogel, F. Maxfield, 1995, The Journal of cell biology.

Intracellular routes and selective retention of antigens in mildly acidic cathepsin D/lysosome-associated membrane protein-1/MHC class II-positive vesicles in immature dendritic cells.

P. Ricciardi-Castagnoli, J. Davoust, H. Geuze, 1997, Journal of immunology.

3‐D Structure of Multilaminar Lysosomes in Antigen Presenting Cells Reveals Trapping of MHC II on the Internal Membranes

M. N. Lebbink, B. Humbel, A. Verkleij, 2004, Traffic.

Multivesicular Bodies Are an Intermediate Stage in the Formation of Platelet α-Granules

N. Debili, J. Sixma, H. Geuze, 1998 .

The tetraspan protein CD82 is a resident of MHC class II compartments where it associates with HLA-DR, -DM, and -DO molecules.

P. Cresswell, H. Geuze, C. Hammond, 1998, Journal of immunology.

Major Histocompatibility Complex Class II Compartments in Human and Mouse B Lymphoblasts Represent Conventional Endocytic Compartments

A. Rudensky, H. Geuze, M. Kleijmeer, 1997, The Journal of cell biology.

SNX1 Defines an Early Endosomal Recycling Exit for Sortilin and Mannose 6‐Phosphate Receptors

H. Geuze, P. Cullen, W. Geerts, 2008, Traffic.

Mammalian GGAs act together to sort mannose 6-phosphate receptors

H. Geuze, S. Kornfeld, P. Ghosh, 2003, The Journal of cell biology.

Rab4 regulates formation of synaptic-like microvesicles from early endosomes in PC12 cells.

R. Kelly, H. Geuze, P. van der Sluijs, 2001, Molecular biology of the cell.

Effects of mefenamic acid on menstrual hemostasis in essential menorrhagia.

H. Geuze, J. Sixma, H. Geuze, 1992, American journal of obstetrics and gynecology.

Immunogenic peptides bind to class II MHC molecules in an early lysosomal compartment.

H. Geuze, C. Harding, 1993, Journal of immunology.

The role of endosomes and lysosomes in MHC class II functioning.

H. Geuze, 1998, Immunology today.

How MHC class II molecules reach the endocytic pathway.

H. Ploegh, M. Yilla, P. Benaroch, 1995, The EMBO journal.

Peptide Loading in the Endoplasmic Reticulum Accelerates Trafficking of Peptide:MHC Class II Complexes in B Cells

A. Rudensky, H. Geuze, G. Raposo, 1999, Journal of Biomedical Science.

Peptide loading in the endoplasmic reticulum accelerates trafficking of peptide:MHC class II complexes in B cells.

A. Rudensky, H. Geuze, G. Raposo, 1999, Journal of biomedical science.

Assembly of an abundant endogenous major histocompatibility complex class II/peptide complex in class II compartments

A. Rudensky, H. Geuze, G. Raposo, 1997, European journal of immunology.

Transport and intracellular distribution of MHC class II molecules and associated invariant chain in normal and antigen-processing mutant cell lines

P. Cresswell, H. Geuze, J. Riberdy, 1994, Journal of Cell Biology.

Exocytosis of Multivesicular Bodies and ?-Granules Microvesicles by Surface Shedding and Exosomes Derived From Activated Platelets Release Two Types of Membrane Vesicles:

J. Sixma, H. Geuze, H. Heijnen, 2012 .

Two monoclonal antibodies generated against human hsp60 show reactivity with synovial membranes of patients with juvenile chronic arthritis

W. van Eden, H. Geuze, M. Lucassen, 1992, The Journal of experimental medicine.

Sorting of endocytosed transferrin and asialoglycoprotein occurs immediately after internalization in HepG2 cells

H. Geuze, W. Stoorvogel, G. Strous, 1987, The Journal of cell biology.

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells

H. Geuze, C. Harding, 1992, The Journal of cell biology.

Major histocompatibility complex class II compartments in human B lymphoblastoid cells are distinct from early endosomes

H. Ploegh, J. Neefjes, P. Peters, 1995, The Journal of experimental medicine.

Antigen capture and major histocompatibility class II compartments of freshly isolated and cultured human blood dendritic cells

W. Kast, C. Melief, H. Geuze, 1995, The Journal of experimental medicine.

Antigen Storage Compartments in Mature Dendritic Cells Facilitate Prolonged CTL Cross- Priming Capacity

C. Melief, H. Geuze, Selina Khan, 2010 .

Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity

D. Filippov, C. Melief, H. Geuze, 2009, Proceedings of the National Academy of Sciences.

The Fc g RIa (CD64) Ligand Binding Chain Triggers Major Histocompatibility Complex Class II Antigen Presentation Independently of Its Associated FcR g -Chain

H. Geuze, M. Kleijmeer, T. Keler, 1999 .

Immunocytochemical Localization of Albumin and Factor XIII in Thin Cryo Sections of Human Blood Platelets

H. Geuze, J. Sixma, H. Geuze, 1984, Thrombosis and Haemostasis.

Activated platelets release two types of membrane vesicles: microvesicles by surface shedding and exosomes derived from exocytosis of multivesicular bodies and alpha-granules.

J J Sixma, J. Sixma, H. Geuze, 1999, Blood.

II-Expressing Microvesicles at Their Surface Follicular Dendritic Cells Carry MHC Class

H. Geuze, M. Kleijmeer, M. Eijk, 2000 .

Major Histocompatibility Complex Class 1I Compartments in Human B Lymphoblastoid Cells Are Distinct from Early Endosomes By Peter J. Peters,* Gra~a Raposo,* Jacques J. Neefjes,~

H. Ploegh, H. Geuze, V. Oorschot, 1995 .

Functional and ultrastructural aspects of antigen processing by dendritic cells.

W. Kast, C. Melief, H. Geuze, 1995, Advances in experimental medicine and biology.

Polarized expression of major histocompatibility complex class I molecules in human endometrial and endocervical epithelial cells

P. Peters, H. Geuze, M. van Eijkeren, 1991, European journal of immunology.

The pathways of endocytosed transferrin and secretory protein are connected in the trans-Golgi reticulum

H. Geuze, H. Geuze, W. Stoorvogel, 1988, The Journal of cell biology.

Primaquine interferes with membrane recycling from endosomes to the plasma membrane through a direct interaction with endosomes which does not involve neutralisation of endosomal pH nor osmotic swelling of endosomes.

H. Geuze, W. Stoorvogel, A. van Weert, 2000, European journal of cell biology.

The tyrosine‐based lysosomal targeting signal in lamp‐1 mediates sorting into Golgi‐derived clathrin‐coated vesicles.

H. Geuze, W. Hunziker, J. Griffith, 1996, The EMBO journal.

Differences in the endosomal distributions of the two mannose 6- phosphate receptors

H. Geuze, K. von Figura, H. Geuze, 1993, The Journal of cell biology.

The Dileucine Motif Within the Tail of MPR46 is Required for Sorting of the Receptor in Endosomes

H. Geuze, K. von Figura, H. Geuze, 2000, Traffic.

39 kDa receptor‐associated protein is an ER resident protein and molecular chaperone for LDL receptor‐related protein.

H. Geuze, H. Geuze, A. Schwartz, 1995, The EMBO journal.

Identification of two types of beta-COP vesicles in the Golgi complex of rat spermatids.

H. Geuze, J. Ballesta, J. A. Martínez-Menárguez, 1996, European journal of cell biology.

A new model for lethal hit delivery by cytotoxic T lymphocytes.

P. Peters, H. Geuze, J. Borst, 1990, Immunology today.

MHC class II compartments and the kinetics of antigen presentation in activated mouse spleen dendritic cells.

W. Kast, C. Melief, J. Neefjes, 1995, Journal of immunology.

Caveolae can be alternative endocytotic structures in elicited macrophages.

H. Geuze, H. Geuze, A. Kiss, 1997, European journal of cell biology.

A newly identified antigen retention compartment in the FSDC precursor dendritic cell line.

P. Ricciardi-Castagnoli, J. Davoust, H. Geuze, 1997, Advances in experimental medicine and biology.

Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T-cells is dependent on pH.

P. Peters, H. Geuze, J. Borst, 1990, Biochemistry.

Epitopes of apolipoprotein B-100 and B-48 in both liver and intestine. Expression and evidence for local synthesis in recessive abetalipoproteinemia.

Y. Marcel, H. Geuze, L. Havekes, 1986, The Journal of clinical investigation.

Lysosomal acid phosphatase is internalized via clathrin-coated pits.

C. Peters, K. von Figura, H. Geuze, 1992, European journal of cell biology.

Arabidopsis Sterol Endocytosis Involves Actin-Mediated Trafficking via ARA6-Positive Early Endosomes

A. Nakano, W. Möbius, H. Geuze, 2003, Current Biology.

Supplemental Data Arabidopsis Sterol Endocytosis Involves Actin-Mediated Trafficking via ARA 6-Positive Early Endosomes

A. Nakano, W. Möbius, H. Geuze, 2003 .

Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes

J. Slot, H. Geuze, P. Peters, 1991, The Journal of experimental medicine.

Misfolded major histocompatibility complex class I molecules accumulate in an expanded ER-Golgi intermediate compartment

H. Ploegh, H. Geuze, G. Raposo, 1995, The Journal of cell biology.

Overall major histocompatibility complex class I expression is not downregulated in cervix cancer, as detected by immunoelectron microscopy

H. Geuze, V. Oorschot, J. Roovers, 2003, International Journal of Gynecologic Cancer.

Selective Enrichment of Tetraspan Proteins on the Internal Vesicles of Multivesicular Endosomes and on Exosomes Secreted by Human B-lymphocytes*

H. Geuze, W. Stoorvogel, M. Kleijmeer, 1998, The Journal of Biological Chemistry.

Late endosomes derive from early endosomes by maturation

H. Geuze, W. Stoorvogel, V. Oorschot, 1991, Cell.

Accumulation of HLA-DM, a regulator of antigen presentation, in MHC class II compartments.

J. Trowsdale, J. Neefjes, H. Geuze, 1994, Science.

B lymphocytes secrete antigen-presenting vesicles

C. Melief, H. Geuze, W. Stoorvogel, 1996, The Journal of experimental medicine.

A novel class of clathrin-coated vesicles budding from endosomes

H. Geuze, W. Stoorvogel, V. Oorschot, 1996, The Journal of cell biology.

Exosome: from internal vesicle of the multivesicular body to intercellular signaling device.

H. Geuze, W. Stoorvogel, M. Kleijmeer, 2000, Journal of cell science.

Activated Platelets Release Two Types of Membrane Vesicles: Microvesicles by Surface Shedding and Exosomes Derived From Exocytosis of Multivesicular Bodies and -Granules

J. Sixma, H. Geuze, H. Heijnen, 1999 .

Involvement of the endoplasmic reticulum in peroxisome formation.

H. Tabak, A. Verkleij, A. Koster, 2003, Molecular biology of the cell.

CHAPTERR 3 THEE ER-PEROXISOME CONNECTION : THE PEROXISOMALL MEMBRANE PROTEINS PEX 13 P AND PMP 700 ARE FOUND IN SPECIALIZED ER DOMAINS , LAMELLAE , , AND PEROXISOMES IN MOUSE DENDRITICC CELLS

H. Geuze, B. Distel, J. Griffith, 2007 .

Glutaraldehyde Fixation of Human Blood Platelets

J. Sixma, H. Geuze, W. Linssen, 1972, Thrombosis and Haemostasis.

Immature Dendritic Cells Acquire Cd8+Cytotoxic T Lymphocyte Priming Capacity upon Activation by T Helper Cell–Independent or–Dependent Stimuli

P. Ricciardi-Castagnoli, R. Offringa, C. Melief, 2000, The Journal of experimental medicine.

Immuno-electron microscopical demonstration of lysosomes in human blood platelets and megakaryocytes using anti-cathepsin D.

J. Sixma, K. von Figura, H. Geuze, 1985, Blood.

Reorganization of multivesicular bodies regulates MHC class II antigen presentation by dendritic cells

A. Rudensky, P. Ricciardi-Castagnoli, C. Melief, 2001, The Journal of cell biology.

Antigen Loading of MHC Class I Molecules in the Endocytic Tract

C. Melief, A. Osterhaus, H. Geuze, 2001, Traffic.

Multivesicular bodies are an intermediate stage in the formation of platelet alpha-granules.

N. Debili, J. Sixma, H. Geuze, 1998, Blood.

Molecules relevant for T cell‐target cell interaction are present in cytolytic granules of human T lymphocytes

Peter J. Peters, Hans J. Geuze, Hans A. Der Van Donk, 1989, European journal of immunology.

Antigen processing and intracellular traffic of antigens and MHC molecules.

H. Geuze, C. Harding, 1993, Current opinion in cell biology.

Secretory Lysosomes and the Production of Exosomes

H. Geuze, G. Raposo, M. Vidal, 1997 .

Peptide-induced stabilization and intracellular localization of empty HLA class I complexes

H. Ploegh, P. Peters, H. Geuze, 1992, The Journal of experimental medicine.

Slow endocytosis of the LDL receptor-related protein 1B: implications for a novel cytoplasmic tail conformation.

H. Geuze, Yonghe Li, A. Schwartz, 2007, Experimental cell research.

The plasticity of multivesicular bodies and the regulation of antigen presentation.

H. Geuze, W. Stoorvogel, M. Kleijmeer, 2002, Seminars in cell & developmental biology.

Immunocytochemical localization of acrosin and hyaluronidase in epididymal and ejaculated porcine spermatozoa.

H. Geuze, R. Willemsen, J. de Vries, 1985, European journal of cell biology.

EJCB-Lecture. A novel lysosomal compartment engaged in antigen presentation.

H. Geuze, 1994, European journal of cell biology.

Processing of bacterial antigens for presentation to class I and II MHC-restricted T lymphocytes.

H. Geuze, J. Pfeifer, C. Harding, 1995, Infectious agents and disease.

Evidence for a nonlysosomal origin of the acrosome.

H. Geuze, J. Ballesta, J. A. Martínez-Menárguez, 1996, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Heterogeneous behavior of cells with respect to induction of retrograde transport from the trans-Golgi network to the Golgi upon inhibition of the vacuolar proton pump.

H. Geuze, W. Stoorvogel, A. van Weert, 1997, European journal of cell biology.

The FcgammaRIa (CD64) ligand binding chain triggers major histocompatibility complex class II antigen presentation independently of its associated FcR gamma-chain.

H. Geuze, M. Kleijmeer, T. Keler, 1999, Blood.

Immunoelectron microscopy of antigen processing in dendritic cells.

H. Geuze, H. Geuze, M. Kleijmeer, 2001, Methods in molecular medicine.

Synaptic vesicles form by budding from tubular extensions of sorting endosomes in PC12 cells.

R. Kelly, H. Geuze, P. van der Sluijs, 1999, Molecular biology of the cell.

Endosomal compartmentalization in three dimensions: Implications for membrane fusion

A. J. Koster, B. Humbel, A. Verkleij, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Characterization of the TGN exit signal of the human mannose 6-phosphate uncovering enzyme

Robert F Murphy, Prashant Nair, R. Murphy, 2005, Journal of Cell Science.

B lymphocytes secrete antigen-presenting vesicles

C. Melief, H. Geuze, W. Stoorvogel, 1996, The Journal of experimental medicine.

The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts

J. Slot, H. Geuze, H. Geuze, 1996, The Journal of cell biology.

Class II MHC molecules are present in macrophage lysosomes and phagolysosomes that function in the phagocytic processing of Listeria monocytogenes for presentation to T cells

H. Geuze, C. Harding, 1992, The Journal of cell biology.

Subcellular localization of Forssman glycolipid in epithelial MDCK cells by immuno-electronmicroscopy after freeze-substitution

J. Slot, H. Geuze, H. Geuze, 1991, The Journal of cell biology.

Characterization of MHC Class II Compartments by Immunoelectron Microscopy

H. Geuze, M. Kleijmeer, Kleijmeer, 1996, Methods.