D. Zarkower

发表

W. Yi, D. Zarkower, Woelsung Yi, 1999, Development.

Establishing sexual dimorphism: conservation amidst diversity?

D. Zarkower, 2001, Nature Reviews Genetics.

Identification of sex‐specific molecular markers using restriction site‐associated DNA sequencing

T. Gamble, D. Zarkower, TONY GAMBLE, 2014, Molecular ecology resources.

A sex-specific transcription factor controls male identity in a simultaneous hermaphrodite

J. Collins, D. Zarkower, P. Newmark, 2013, Nature Communications.

Invertebrates may not be so different after all.

D. Zarkower, 2002, Novartis Foundation symposium.

Sexually dimorphic expression of multiple doublesex-related genes in the embryonic mouse gonad.

D. Zarkower, Shinseog Kim, V. Bardwell, 2003, Gene expression patterns : GEP.

Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation.

D. Zarkower, Shinseog Kim, V. Bardwell, 2007, Developmental Biology.

Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells

K. Nakayama, D. Zarkower, T. Nakagawa, 2017, Development.

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testis

A. Minkina, D. Zarkower, V. Bardwell, 2022, PLoS genetics.

Interaction between DMRT1 function and genetic background modulates signaling and pluripotency to control tumor susceptibility in the fetal germ line.

M. Griswold, D. Zarkower, A. Sarver, 2013, Developmental biology.

Karyotypes of two species of Malagasy ground gecko (Paroedura: Gekkonidae)

T. Gamble, D. Zarkower, H. Main, 2012 .

DMRT genes in vertebrate gametogenesis.

D. Zarkower, 2013, Current topics in developmental biology.

DMRT1 prevents female reprogramming in the postnatal mammalian testis.

M. Griswold, D. Zarkower, A. Sarver, 2011, Nature.

Temperature‐dependent expression of turtle Dmrt1 prior to sexual differentiation

C. S. Raymond, D. Zarkower, J. R. Kettlewell, 2000, Genesis.

Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary.

A. Minkina, D. Zarkower, N. Ghyselinck, 2017, Developmental biology.

Direct protein-protein interaction between the intracellular domain of TRA-2 and the transcription factor TRA-1A modulates feminizing activity in C. elegans.

P. Kuwabara, D. Zarkower, A. Spence, 2000, Genes & development.

classical poly ( A ) polymerase . The enzyme that adds poly ( A ) to mRNAs is a

M. Wickens, D. Zarkower, M. Edmonds, 2003 .

The enzyme that adds poly(A) to mRNAs is a classical poly(A) polymerase

M. Wickens, D. Zarkower, M. Edmonds, 1990, Molecular and cellular biology.

The AAUAAA sequence is required both for cleavage and for polyadenylation of simian virus 40 pre-mRNA in vitro

M. Wickens, D. Zarkower, M. Sheets, 1986, Molecular and cellular biology.

The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency

Matthew S. Cook, L. Looijenga, M. Griswold, 2009, Proceedings of the National Academy of Sciences.

Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads.

C. S. Raymond, D. Zarkower, A. Kuroiwa, 2014, Developmental biology.

DMRT1 Is Required for Mouse Spermatogonial Stem Cell Maintenance and Replenishment

D. Zarkower, V. Bardwell, J. Oatley, 2016, PLoS genetics.

DMRT1 protects male gonadal cells from retinoid-dependent sexual transdifferentiation.

A. Minkina, D. Zarkower, N. Ghyselinck, 2014, Developmental cell.

DMRT1: An Ancient Sexual Regulator Required for Human Gonadogenesis

D. Zarkower, Mark W Murphy, M. Murphy, 2021, Sexual Development.

Regulatory rearrangements and smg-sensitive alleles of the C. elegans sex-determining gene tra-1.

M. de Bono, J. Hodgkin, D. Zarkower, 1994, Developmental genetics.

Dmrt1, a gene related to worm and fly sexual regulators, is required for mammalian testis differentiation.

C. S. Raymond, D. Zarkower, M. G. O’Sullivan, 2000, Genes & development.

Evidence for evolutionary conservation of sex-determining genes

C. S. Raymond, J. Hodgkin, D. Zarkower, 1998, Nature.

Alteration by prolactin of surface charge and membrane fluidity of rat 13762 mammary ascites tumor cells

D. Zarkower, A. Keith, P. Todd, 1984, Cell Biophysics.

Expression of Dmrt1 in the genital ridge of mouse and chicken embryos suggests a role in vertebrate sexual development.

C. S. Raymond, D. Zarkower, V. Bardwell, 1999, Developmental biology.

A region of human chromosome 9p required for testis development contains two genes related to known sexual regulators.

C. S. Raymond, L. Brown, D. Page, 1999, Human molecular genetics.

The mammalian doublesex homolog DMRT1 is a transcriptional gatekeeper that controls the mitosis versus meiosis decision in male germ cells.

M. Griswold, D. Zarkower, S. Yoshida, 2010, Developmental cell.

mRNA Expression Analysis and the Molecular Basis of Neonatal Testis Defects in Dmrt1 Mutant Mice

D. Zarkower, V. Bardwell, Mark W Murphy, 2006, Sexual Development.

DMRT1 prevents female reprogramming in the postnatal mammalian testis

M. Griswold, D. Zarkower, A. Sarver, 2011, Nature.

Mice Mutant in the DM Domain Gene Dmrt4 Are Viable and Fertile but Have Polyovular Follicles

D. Zarkower, J. Balciuniene, V. Bardwell, 2006, Molecular and Cellular Biology.

A Mammal-Specific Doublesex Homolog Associates with Male Sex Chromatin and Is Required for Male Meiosis

Jeannie T. Lee, D. Zarkower, S. Namekawa, 2007, PLoS genetics.

ANOLIS SEX CHROMOSOMES ARE DERIVED FROM A SINGLE ANCESTRAL PAIR

Anthony J. Geneva, T. Gamble, D. Zarkower, 2014, Evolution; international journal of organic evolution.

The mammalian Doublesex homolog DMRT6 coordinates the transition between mitotic and meiotic developmental programs during spermatogenesis

D. Zarkower, V. Bardwell, Mark W Murphy, 2014, Development.

Non-Homologous Sex Chromosomes in Two Geckos (Gekkonidae: Gekkota) with Female Heterogamety

J. Graves, T. Gamble, D. Zarkower, 2014, Cytogenetic and Genome Research.

DMRT1 in a ratite bird: evidence for a role in sex determination and discovery of a putative regulatory element

J. Graves, D. Zarkower, P. Kirby, 2002, Cytogenetic and Genome Research.

Targeted disruption of the DM domain containing transcription factor Dmrt2 reveals an essential role in somite patterning.

Randy L. Johnson, D. Zarkower, H. Kokubo, 2006, Developmental biology.

Evolutionary Dynamics of the DM Domain Gene Family in Metazoans

J. Volff, M. Schartl, D. Zarkower, 2003, Journal of Molecular Evolution.

Sex and the singular DM domain: insights into sexual regulation, evolution and plasticity

D. Zarkower, Clinton K. Matson, 2012, Nature Reviews Genetics.

Temporal changes of Sall4 lineage contribution in developing embryos and the contribution of Sall4-lineages to postnatal germ cells in mice

Y. Kawakami, D. Zarkower, H. Kawakami, 2018, Scientific Reports.

Restriction Site-Associated DNA Sequencing (RAD-seq) Reveals an Extraordinary Number of Transitions among Gecko Sex-Determining Systems.

T. Gamble, D. Zarkower, Joshua Lynch, 2015, Molecular biology and evolution.

A forkhead protein controls sexual identity of the C. elegans male somatic gonad

D. Zarkower, J. Kimble, L. Mathies, 2004, Development.

DMRT proteins and coordination of mammalian spermatogenesis.

D. Zarkower, Teng Zhang, 2017, Stem cell research.

An ancient protein-DNA interaction underlying metazoan sex determination

Hideki Aihara, Surajit Banerjee, Ken McElreavey, 2015, Nature Structural &Molecular Biology.

A DM domain protein from a coral, Acropora millepora, homologous to proteins important for sex determination

Steven W. Miller, D. Hayward, E. Ball, 2003, Evolution & development.

Genome-wide analysis of DNA binding and transcriptional regulation by the mammalian Doublesex homolog DMRT1 in the juvenile testis

Kenny Q. Ye, A. Melnick, D. Zarkower, 2010, Proceedings of the National Academy of Sciences.

Mab-3 is a direct tra-1 target gene regulating diverse aspects of C. elegans male sexual development and behavior.

W. Yi, D. Zarkower, J. M. Ross, 2000, Development.

Dominant feminizing mutations implicate protein-protein interactions as the main mode of regulation of the nematode sex-determining gene tra-1.

M. de Bono, J. Hodgkin, D. Zarkower, 1995, Genes & development.

Molecular analysis of the C. elegans sex-determining gene tra-1: A gene encoding two zinc finger proteins

J. Hodgkin, D. Zarkower, 1992, Cell.

Sexual Cell-Fate Reprogramming in the Ovary by DMRT1

A. Minkina, D. Zarkower, Anthony D. Krentz, 2015, Current Biology.

The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.

C. Filippis, M. Götz, S. De Clercq, 2013, Cerebral cortex.

Zinc fingers in sex determination: only one of the two C. elegans Tra-1 proteins binds DNA in vitro.

J. Hodgkin, D. Zarkower, Jonathan Hodgkin, 1993, Nucleic acids research.

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

D. Zarkower, V. Bardwell, M. Murphy, 2007, BMC Molecular Biology.

Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development.

D. Zarkower, P. Koopman, K. Loffler, 2003, Endocrinology.

Polyadenylation of mRNA: minimal substrates and a requirement for the 2' hydroxyl of the U in AAUAAA

M. Wickens, D. Zarkower, M. Sheets, 1990 .

Polyadenylation of mRNA: minimal substrates and a requirement for the 2' hydroxyl of the U in AAUAAA

M. Wickens, D. Zarkower, M. Sheets, 1990, Molecular and cellular biology.

Formation of mRNA 3′ termini: stability and dissociation of a complex involving the AAUAAA sequence.

M. Wickens, D. Zarkower, M Wickens, 1987, The EMBO journal.

MPK-1 ERK controls membrane organization in C. elegans oogenesis via a sex-determination module.

T. Schedl, D. Zarkower, Swathi Arur, 2011, Developmental cell.

In mammalian foetal testes, SOX9 regulates expression of its target genes by binding to genomic regions with conserved signatures

D. Zarkower, N. Bellora, V. Harley, 2017, Nucleic acids research.

The conserved sex regulator DMRT1 recruits SOX9 in sexual cell fate reprogramming

D. Zarkower, V. Bardwell, Mark W Murphy, 2021, Nucleic acids research.

A functionally redundant downstream sequence in SV40 late pre-mRNA is required for mRNA 3'-end formation and for assembly of a precleavage complex in vitro.

M. Wickens, D. Zarkower, Marvin Wickens, 1988, The Journal of biological chemistry.

DMRT1 promotes oogenesis by transcriptional activation of Stra8 in the mammalian fetal ovary.

M. Griswold, D. Zarkower, A. Sarver, 2011, Developmental biology.

Somatic sexual differentiation in Caenorhabditis elegans.

D. Zarkower, Jennifer Ross Wolff, 2008, Current topics in developmental biology.

Somatic sex determination.

D. Zarkower, 2006, WormBook : the online review of C. elegans biology.

DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation

S. De Clercq, E. Bellefroid, Y. Nakagawa, 2016, Cerebral cortex.

Polycomb group regulation of Hox gene expression in C. elegans.

D. Zarkower, J. M. Ross, 2003, Developmental cell.

Specific pre‐cleavage and post‐cleavage complexes involved in the formation of SV40 late mRNA 3′ termini in vitro.

M. Wickens, D. Zarkower, M Wickens, 1987, The EMBO journal.

DMRT5, DMRT3, and EMX2 Cooperatively Repress Gsx2 at the Pallium–Subpallium Boundary to Maintain Cortical Identity in Dorsal Telencephalic Progenitors

S. De Clercq, E. Bellefroid, T. Lingner, 2018, The Journal of Neuroscience.

TRA-1 ChIP-seq reveals regulators of sexual differentiation and multilevel feedback in nematode sex determination

J. Lieb, Kohta Ikegami, D. Zarkower, 2013, Proceedings of the National Academy of Sciences.

Sex determination

T. Gamble, D. Zarkower, 1966, Current Biology.

The DM domain protein DMRT1 is a dose-sensitive regulator of germ cell pluripotency

D. Zarkower, V. Bardwell, M. Murphy, 2009 .

DM Domain Genes

D. Zarkower, 2002 .

Genome-wide analysis of sex-enriched gene expression during C. elegans larval development.

V. Reinke, W. Yi, D. Zarkower, 2005, Developmental biology.

chinmo Mutant fly testis stem cells switching sex farewell to maleness.

D. Zarkower, 2014, Developmental cell.

Genetic manipulation of sex ratio in mammals: the Reaper comes for Mickey

M. Smanski, D. Zarkower, 2019, EMBO reports.

Evidence forevolutionary conservationof sex-determininggenes

C. S. Raymond, J. Hodgkin, D. Zarkower, 2022 .

DSH-2 regulates asymmetric cell division in the early C. elegans somatic gonad

D. Zarkower, Weiru Chang, C. Lloyd, 2005, Mechanisms of Development.

The DM domain protein MAB-3 promotes sex-specific neurogenesis in C. elegans by regulating bHLH proteins.

D. Zarkower, Mark W Murphy, M. Murphy, 2005, Developmental cell.

Sexually Dimorphic unc-6/Netrin Expression Controls Sex-Specific Maintenance of Synaptic Connectivity

O. Hobert, D. Zarkower, Peter Weinberg, 2018, Current Biology.

EGL-5/ABD-B plays an instructive role in male cell fate determination in the C. elegans somatic gonad.

D. Zarkower, Mark W Murphy, M. Murphy, 2010, Developmental biology.

Functional Genomic Identification of Genes Required for Male Gonadal Differentiation in Caenorhabditis elegans

Mary B. Kroetz, D. Zarkower, A. Kalis, 2010, Genetics.

Over-expression of DMRT1 induces the male pathway in embryonic chicken gonads.

C. S. Raymond, D. Zarkower, A. Kuroiwa, 2014, Developmental biology.

DMRT5, DMRT3, and EMX2 Cooperatively Repress Gsx2 at the Pallium–Subpallium Boundary to Maintain Cortical Identity in Dorsal Telencephalic Progenitors

S. De Clercq, E. Bellefroid, T. Lingner, 2018, The Journal of Neuroscience.

ANOLIS SEX CHROMOSOMES ARE DERIVED FROM A SINGLE ANCESTRAL PAIR

Anthony J. Geneva, T. Gamble, D. Zarkower, 2014, Evolution; international journal of organic evolution.

Vertebrate DM domain proteins bind similar DNA sequences and can heterodimerize on DNA

D. Zarkower, V. Bardwell, Mark W Murphy, 2007, BMC Molecular Biology.

Environmental Influences on Epigenetic Regulation

D. Zarkower, S. Namekawa, Shinseog Kim, 2005, Environmental Health Perspectives.

Bmc Molecular Biology Vertebrate Dm Domain Proteins Bind Similar Dna Sequences and Can Heterodimerize on Dna

D. Zarkower, V. Bardwell, Mark W Murphy, 2022 .

Bmc Molecular Biology Vertebrate Dm Domain Proteins Bind Similar Dna Sequences and Can Heterodimerize on Dna

D. Zarkower, V. Bardwell, Mark W Murphy, 2022 .

Cell-Specific mRNA Profiling of the Caenorhabditis elegans Somatic Gonadal Precursor Cells Identifies Suites of Sex-Biased and Gonad-Enriched Transcripts

Mary B. Kroetz, D. Zarkower, 2015, G3: Genes, Genomes, Genetics.