D. Steinberg

发表

Preventing coronary artery disease by lowering cholesterol levels: fifty years from bench to bedside.

A. Gotto, D. Steinberg, Daniel Steinberg, 1999, JAMA.

Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.

J L Witztum, D. Steinberg, J. Witztum, 1984, Proceedings of the National Academy of Sciences of the United States of America.

Decrease in Reactive Amino Groups during Oxidation or Endothelial Cell Modification of LDL: Correlation with Changes in Receptor‐Mediated Cataboiism

D. Steinberg, J. Witztum, U. Steinbrecher, 1987, Arteriosclerosis.

Beyond cholesterol. Modifications of low-density lipoprotein that increase its atherogenicity.

J L Witztum, T. Carew, D. Steinberg, 1989, The New England journal of medicine.

Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts.

D. Steinberg, S. Ylä-Herttuala, J. Witztum, 1991, The Journal of clinical investigation.

Viscosity of culture medium as a regulator of synthesis and secretion of very low density lipoproteins by cultured hepatocytes.

D. Steinberg, G. Schonfeld, W. Patsch, 1982, The Journal of biological chemistry.

Lipoproteins and the pathogenesis of atherosclerosis.

D. Steinberg, D Steinberg, 1987, Circulation.

Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. The Expert Panel.

Daniel Steinberg, D. Roger Illingworth, Gustav Schonfeld, 1988, Archives of internal medicine.

The Cholesterol Wars

D. Steinberg, 2007 .

Scavenger Receptors, Oxidized LDL, and Atherosclerosis

E. Dennis, D. Steinberg, J. Witztum, 2001, Annals of the New York Academy of Sciences.

George Lyman Duff Memorial Lecture Lipoproteins and Atherosclerosis

D. Steinberg, 2005 .

A Look Back and a Look Ahead

D. Steinberg, 2005 .

Role of the Low Density Lipoprotein Receptor in Penetration of Low Density Lipoprotein into Rabbit Aortic Wall

T. Carew, D. Steinberg, O. Wiklund, 1985, Arteriosclerosis.

Measurement in vivo of irreversible degradation of low density lipoprotein in the rabbit aorta. Predominance of intimal degradation.

T. Carew, D. Steinberg, R. Pittman, 1984, Arteriosclerosis.

INTERACTIONS OF PLASMA LIPOPROTEINS WITH ENDOTHELIAL CELLS *

D. Steinberg, E. Mahoney, T. Henriksen, 1982, Annals of the New York Academy of Sciences.

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

V. Ord, D. Steinberg, J. Breslow, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

Endothelial cell-derived chemotactic activity for mouse peritoneal macrophages and the effects of modified forms of low density lipoprotein.

D. Steinberg, S. Parthasarathy, M. Quinn, 1985, Proceedings of the National Academy of Sciences of the United States of America.

The cholesterol controversy is over. Why did it take so long?

D. Steinberg, D. Steinberg, 1989, Circulation.

The role of lipoprotein lipase in the metabolism of triglyceride-rich lipoproteins by macrophages.

J. Little, D. Steinberg, J. Witztum, 1983, The Journal of biological chemistry.

Infusion of long-chain fatty acid anions by continuous-flow centrifugation.

D. Steinberg, W. Greenough, S. Crespin, 1969, The Journal of clinical investigation.

Identification of the lectin-like receptor for oxidized low-density lipoprotein in human macrophages and its potential role as a scavenger receptor.

D. Steinberg, O. Quehenberger, N. Kondratenko, 1998, The Biochemical journal.

Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis.

D. Steinberg, L. Fong, S. Parthasarathy, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Kinetic model for production and metabolism of very low density lipoprotein triglycerides. Evidence for a slow production pathway and results for normolipidemic subjects.

S. Grundy, D. Steinberg, M. Berman, 1979, The Journal of clinical investigation.

Antioxidants and atherosclerosis. A current assessment.

D. Steinberg, 1991, Circulation.

Oxidized LDL, its Receptors, and its Role in Atherosclerosis

D. Steinberg, 1996 .

Role of oxidized LDL and antioxidants in atherosclerosis.

D. Steinberg, Daniel Steinberg, D. Steinberg, 1995, Advances in experimental medicine and biology.

Effect of the antioxidant N,N'-diphenyl 1,4-phenylenediamine (DPPD) on atherosclerosis in apoE-deficient mice.

D. Steinberg, R. Tangirala, E. Miller, 1995, Arteriosclerosis, thrombosis, and vascular biology.

Inhibition of hypercholesterolemia-induced atherosclerosis in the nonhuman primate by probucol. I. Is the extent of atherosclerosis related to resistance of LDL to oxidation?

P. Wahl, A. Chait, T. Carew, 1994, The Journal of clinical investigation.

Modified forms of low‐density lipoprotein and atherosclerosis

D. Steinberg, 1993, Journal of internal medicine.

Oxidatively Modified LDL and Atherosclerosis

D. Steinberg, 1993 .

Oxidative modification of low density lipoprotein

D. Steinberg, 1990 .

A novel mechanism by which probucol lowers low density lipoprotein levels demonstrated in the LDL receptor-deficient rabbit.

T. Carew, D. Steinberg, J. Witztum, 1984, Journal of lipid research.

Probucol inhibits oxidative modification of low density lipoprotein.

S. Young, D. Steinberg, J. Witztum, 1986, The Journal of clinical investigation.

Studies on the mechanism of action of probucol.

D. Steinberg, D. Steinberg, 1986, The American journal of cardiology.

CHAPTER 7 – The 1984 Coronary Primary Prevention Trial: The Keystone in the Arch of Evidence Linking Blood Cholesterol to Coronary Heart Disease

D. Steinberg, 2007 .

Chance and Serendipity in Science: Two Examples from My Own Career

D. Steinberg, 2011, The Journal of Biological Chemistry.

Oxidized low-density lipoprotein and atherosclerosis.

D. Steinberg, J. Witztum, 2010, Arteriosclerosis, thrombosis, and vascular biology.

Correlation of Antiphospholipid Antibody Recognition with the Structure of Synthetic Oxidized Phospholipids

E. Dennis, D. Steinberg, J. Witztum, 2002, The Journal of Biological Chemistry.

Oxidized phospholipids, linked to apolipoprotein B of oxidized LDL, are ligands for macrophage scavenger receptors.

D. Steinberg, J. Witztum, S. Hörkkö, 2000, Journal of lipid research.

Enhanced Macrophage Degradation of Biologically Modified Low Density Lipoprotein

D. Steinberg, E. Mahoney, T. Henriksen, 1983, Arteriosclerosis.

Essential role of phospholipase A2 activity in endothelial cell-induced modification of low density lipoprotein.

D. Steinberg, J. Witztum, U. Steinbrecher, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Macrophage Oxidation of Low Density Lipoprotein Generates a Modified Form Recognized by the Scavenger Receptor

D. Steinberg, D. Printz, S. Parthasarathy, 1986, Arteriosclerosis.

Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor.

D. Steinberg, L. Fong, S. Parthasarathy, 1987, Proceedings of the National Academy of Sciences of the United States of America.

A macrophage receptor that recognizes oxidized low density lipoprotein but not acetylated low density lipoprotein.

D. Steinberg, S. Parthasarathy, C. Sparrow, 1989, The Journal of biological chemistry.

Isolation and analysis of lipoproteins secreted by rat liver hepatocytes.

D. Vance, D. Steinberg, D. B. Weinstein, 1984, Biochimica et biophysica acta.

Intensive combination drug therapy of familial hypercholesterolemia with lovastatin, probucol, and colestipol hydrochloride.

S. Young, R. Weinreb, D. Steinberg, 1989, Circulation.

In celebration of the 100th anniversary of the lipid hypothesis of atherosclerosis

D. Steinberg, 2013, Journal of Lipid Research.

CHAPTER 9 – Summing up

D. Steinberg, 2007 .

Thematic review series : The Pathogenesis of Atherosclerosis An interpretive history of the cholesterol controversy , part V : The discovery of the statins and the end of the controversy 1

D. Steinberg, Daniel Steinberg, 2006 .

Low density lipoprotein rich in oleic acid is protected against oxidative modification: implications for dietary prevention of atherosclerosis.

D. Steinberg, J. Witztum, S. Parthasarathy, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Antioxidants in the prevention of human atherosclerosis. Summary of the proceedings of a National Heart, Lung, and Blood Institute Workshop: September 5-6, 1991, Bethesda, Maryland.

D. Steinberg, D. Steinberg, 1992, Circulation.

Tissue sites of catabolism of rat and human low density lipoproteins in rats.

A. Attie, T. Carew, D. Steinberg, 1982, Biochimica et biophysica acta.

Stimulation of insulin secretion by infusion of free fatty acids.

D. Steinberg, W. Greenough, S. Crespin, 1969, The Journal of clinical investigation.

Effects of medium fatty acid concentration, epinephrine, and glucose on palmitate-l-C14 oxidation and incorporation into neutral lipids by skeletal muscle in vitro

D. Steinberg, Philip Eaton, 1961 .

Purification and characterization of lipoprotein lipase from pig adipose tissue.

D. Steinberg, C. Ehnholm, W. Brown, 1974, The Journal of biological chemistry.

Enzymes regulating glycogen metabolism in swine subcutaneous adipose tissue. II. Glycogen synthase.

D. Steinberg, R. Miller, S. Mayer, 1975, Biochemistry.

Cholesterol esterase in rat adipose tissue and its activation by cyclic adenosine 3':5'-monophosphate-dependent protein kinase.

D. Steinberg, J. Khoo, R. Pittman, 1975, The Journal of biological chemistry.

Enzymes regulating glycogen metabolism in swine subcutaneous adipose tissue. I. Phosphorylase and phosphorylase phosphatase.

D. Steinberg, R. Miller, S. Mayer, 1975, Biochemistry.

Management of hyperlipidemia. Diet and drugs.

S. Grundy, D. Steinberg, 1978, Archives of surgery.

Effect of Sodium Linoleate Infusion on Plasma Free Fatty Acids, Glucose, Insulin, and Ketones in Unanesthetized Dogs

D. Steinberg, W. Greenough, S. Crespin, 1972, Diabetes.

FATE OF PALMITATE AND OF LINOLEATE PERFUSED THROUGH THE ISOLATED RAT LIVER AT HIGH CONCENTRATIONS.

D. Steinberg, P. Nestel, 1963, Journal of lipid research.

Principles of Nutrition and Dietary Recommendations for Patients with Diabetes Mellitus: 1971

D. Steinberg, N. Spritz, W. Connor, 1971, Diabetes.

CALORIGENIC EFFECT OF NOREPINEPHRINE CORRELATED WITH PLASMA FREE FATTY ACID TURNOVER AND OXIDATION.

E. Buskirk, R. Thompson, D. Steinberg, 1964, The Journal of clinical investigation.

Metabolic Effect of Epinephrine on the QO2 of the Arrested Isolated Perfused Rat Heart

D. Steinberg, D. Challoner, 1965, Nature.

Thematic review series: the pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy: part II: the early evidence linking hypercholesterolemia to coronary disease in humans.

D. Steinberg, 2005, Journal of lipid research.

Enhanced Macrophage Uptake of Low Density Lipoprotein after Self‐Aggregation

D. Steinberg, J. Khoo, E. Miller, 1988, Arteriosclerosis.

A critical look at the evidence for the oxidation of LDL in atherogenesis.

D. Steinberg, Daniel Steinberg, 1997, Atherosclerosis.

NIKOLAI ANITSCHKOW: THE BIRTH OF THE LIPID HYPOTHESIS OF ATHEROSCLEROSIS AND CORONARY HEART DISEASE

D. Steinberg, 2014 .

The statins in preventive cardiology.

D. Steinberg, 2008, The New England journal of medicine.

Statin treatment does not cause cancer.

D. Steinberg, 2008, Journal of the American College of Cardiology.

Antioxidants in the Prevention of Human Atherosclerosis

D. Steinberg, 2005 .

A MECHANISM BY WHICH HIGH-DENSITY LIPOPROTEINS MAY SLOW THE ATHEROGENIC PROCESS

T. Koschinsky, T. Carew, D. Steinberg, 1976, The Lancet.

Binding, internalization, and degradation of low density lipoprotein by normal human fibroblasts and by fibroblasts from a case of homozygous familial hypercholesterolemia.

D. Steinberg, D. B. Weinstein, O. Stein, 1976, Proceedings of the National Academy of Sciences of the United States of America.

Prevention of low density lipoprotein aggregation by high density lipoprotein or apolipoprotein A-I.

D. Steinberg, J. Khoo, E. Miller, 1990, Journal of lipid research.

Sites and mechanisms of uptake and degradation of high density and low density lipoproteins.

D. Steinberg, R. Pittman, Ray C. Pittmsn, 1984, Journal of lipid research.

Lipoprotein and cholesterol metabolism in rabbit arterial endothelial cells in culture.

D. Steinberg, D. B. Weinstein, J. Reckless, 1978, Biochimica et biophysica acta.

The rediscovery of high density lipoprotein: a negative risk factor in atherosclerosis

D. Steinberg, 1978, European journal of clinical investigation.

CHOLESTEROL AND CARDIOVASCULAR DISEASE Lipoproteins and the pathogenesis of atherosclerosis

D. Steinberg, 2022 .

Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy, part IV: The 1984 Coronary Primary Prevention Trial ends it—almost1

D. Steinberg, 2006, Journal of Lipid Research.

Very low density lipoprotein triglyceride transport in type IV hyperlipoproteinemia and the effects of carbohydrate-rich diets.

D. Steinberg, M. Berman, S. Quarfordt, 1970, The Journal of clinical investigation.

RELATIONSHIP BETWEEN FREE FATTY ACID TURNOVER AND TOTAL BODY OXYGEN CONSUMPTION IN THE EUTHYROID AND HYPERTHYROID STATES.

R. P. Eaton, R. Thompson, D. Steinberg, 1965, The Journal of clinical investigation.

Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages.

D. Steinberg, S. Rankin, S. Parthasarathy, 1991, Journal of lipid research.

Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100.

S. Parthasarathy, D. Steinberg, J. Witztum, 1987, Journal of lipid research.

Antioxidant Vitamin Supplements and Cardiovascular Disease

B. Howard, A. Lichtenstein, P. Kris-Etherton, 2004, Circulation.

Is there a potential therapeutic role for vitamin E or other antioxidants in atherosclerosis?

D. Steinberg, 2000, Current opinion in lipidology.

Alcohol and atherosclerosis.

L. Kuller, D. Steinberg, T. Pearson, 1991, Annals of internal medicine.

Dissociation of apoprotein B and triglyceride production in very-low-density lipoproteins.

D. Steinberg, N. Le, W. Brown, 1980, The American journal of physiology.

Serum cholesterol. Doing the right thing.

A. Gotto, S. Grundy, P. Greenland, 1993, Circulation.

Simvastatin with or without ezetimibe in familial hypercholesterolemia.

D. Steinberg, 2008, The New England journal of medicine.

Feasibility of using an oleate-rich diet to reduce the susceptibility of low-density lipoprotein to oxidative modification in humans.

D. Steinberg, P. Reaven, J. Witztum, 1991, The American journal of clinical nutrition.

Transport of very low density lipoprotein triglycerides in varying degrees of obesity and hypertriglyceridemia.

S. Grundy, D. Steinberg, M. Berman, 1979, The Journal of clinical investigation.

Scavenger receptor class B type I as a receptor for oxidized low density lipoprotein.

D. Steinberg, J. Witztum, O. Quehenberger, 2001, Journal of lipid research.

Characterization of CLA-1, a Human Homologue of Rodent Scavenger Receptor BI, as a Receptor for High Density Lipoprotein and Apoptotic Thymocytes*

D. Steinberg, K. Murao, O. Quehenberger, 1997, The Journal of Biological Chemistry.

Independent mechanisms for macrophage binding and macrophage phagocytosis of damaged erythrocytes. Evidence of receptor cooperativity.

D. Steinberg, G. R. Sambrano, V. Terpstra, 1997, Arteriosclerosis, thrombosis, and vascular biology.

Synchronized synthesis and intracellular transport of serum albumin and apolipoprotein B in cultured rat hepatocytes as studied by double immunofluorescence.

S. Singer, D. Steinberg, D. Louvard, 1986, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

Lipoprotein synthesis and secretion by cultured rat hepatocytes. Parallel inhibition of secretion of VLDL, HDL and albumin by monensin.

D. Steinberg, D. B. Weinstein, B. Melin, 1984, Biochimica et biophysica acta.

A practical approach to IVUS for in-stent restenosis and thrombosis

D. Steinberg, 2009 .

Tissue sites of degradation of low density lipoprotein: application of a method for determining the fate of plasma proteins.

A. Attie, T. Carew, D. Steinberg, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Unaltered catabolism of desialylated low-density lipoprotein in the pig and in cultured rat hepatocytes.

H. Freeze, A. Attie, D. Steinberg, 1979, The Biochemical journal.

Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits.

A. Attie, T. Carew, D. Steinberg, 1982, The Journal of biological chemistry.

Inhibition of PCSK9: A powerful weapon for achieving ideal LDL cholesterol levels

D. Steinberg, J. Witztum, 2009, Proceedings of the National Academy of Sciences.

The Search for Cholesterol-lowering Drugs

D. Steinberg, 2007 .

Is the Oxidative Modification Hypothesis Relevant to Human Atherosclerosis?: Do the Antioxidant Trials Conducted to Date Refute the Hypothesis?

D. Steinberg, J. Witztum, 2002, Circulation.

Antioxidant vitamins and coronary heart disease.

D. Steinberg, 1993, The New England journal of medicine.

Arterial Metabolism of Lipoproteins in Relation to Atherogenesis

D. Steinberg, 1990, Annals of the New York Academy of Sciences.

Tissue sites of degradation of apoprotein A-I in the rat.

D. Steinberg, R. Pittman, G. Keller, 1983, The Journal of biological chemistry.

Oxidative Modification of LDL: Epidemiologic and Clinical Considerations

D. Steinberg, 1996 .

In vivo inhibition of foam cell development by probucol in Watanabe rabbits.

T. Carew, D. Steinberg, S. Parthasarathy, 1988, The American journal of cardiology.

Effects of insulin and glucose on very low density lipoprotein triglyceride secretion by cultured rat hepatocytes.

D. Steinberg, P. Durrington, D. B. Weinstein, 1982, The Journal of clinical investigation.

Studies on the synthesis and secretion of serum lipoproteins by rat liver slices.

D. Steinberg, C. Radding, 1960, The Journal of clinical investigation.

Lipoprotein metabolism--new insights from cell biology.

D. Steinberg, 1978, Advances in experimental medicine and biology.

Hypocholesterolemic Drugs and Lipoprotein Metabolism

D. Steinberg, 1987 .

Evidence for a concerted reaction between lipid hydroperoxides and polypeptides.

D. Steinberg, S. Parthasarathy, J. Fruebis, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Secretion of very low density lipoproteins enriched in cholesteryl esters by cultured rat hepatocytes during simulation of intracellular cholesterol esterification.

C. Drevon, D. Steinberg, S. Engelhorn, 1980, Journal of lipid research.

Effect of free fatty acid on the oxygen consumption of perfused rat heart.

D. Steinberg, D. Challoner, 1966, The American journal of physiology.

Dissociation of tissue uptake of cholesterol ester from that of apoprotein A-I of rat plasma high density lipoprotein: selective delivery of cholesterol ester to liver, adrenal, and gonad.

D. Steinberg, D. B. Weinstein, R. Pittman, 1983, Proceedings of the National Academy of Sciences of the United States of America.

Hypoglycaemia and hyperinsulinaemia in response to raised free-fatty-acid levels.

D. Steinberg, W. Greenough, S. Crespin, 1967, Lancet.

Oxidative metabolism of myocardium as influenced by fatty acids and epinephrine.

D. Steinberg, D. Challoner, 1966, The American journal of physiology.

Interaction between high density and low density lipoproteins uptake and degradation by cultured human fibroblasts.

T. Koschinsky, T. Carew, D. Steinberg, 1977, The Journal of clinical investigation.

Is “Antioxidant Status” a Risk Factor?

D. Steinberg, 1998 .

High-density lipoproteins and atherogenesis

D. Steinberg, 1992 .

The LDL modification hypothesis of atherogenesis: an update Published, JLR Papers in Press, November 15, 2009.

D. Steinberg, 2009, Journal of Lipid Research.

The Binding of Oxidized Low Density Lipoprotein to Mouse CD36 Is Mediated in Part by Oxidized Phospholipids That Are Associated with Both the Lipid and Protein Moieties of the Lipoprotein*

E. Dennis, D. Steinberg, J. Witztum, 2000, The Journal of Biological Chemistry.

Receptors for oxidized low-density lipoprotein on elicited mouse peritoneal macrophages can recognize both the modified lipid moieties and the modified protein moieties: implications with respect to macrophage recognition of apoptotic cells.

E. Dennis, D. Steinberg, J. Witztum, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Minimally oxidized low-density lipoprotein increases expression of scavenger receptor A, CD36, and macrosialin in resident mouse peritoneal macrophages.

D. Steinberg, O. Quehenberger, N. Kondratenko, 1998, Arteriosclerosis, thrombosis, and vascular biology.

Effect of probucol on LDL oxidation and atherosclerosis in LDL receptor-deficient mice.

D. Steinberg, R. Tangirala, W. Palinski, 1998, Journal of lipid research.

Macrophage oxidative modification of low density lipoprotein occurs independently of its binding to the low density lipoprotein receptor.

D. Steinberg, R. Tangirala, M. Mol, 1996, Journal of lipid research.

Enhanced Levels of Lipoperoxides in Low Density Lipoprotein Incubated with Murine Fibroblasts Expressing High Levels of Human 15-Lipoxygenase (*)

D. Steinberg, J. Witztum, A. Miyanohara, 1995, The Journal of Biological Chemistry.

Lipoperoxides in LDL incubated with fibroblasts that overexpress 15-lipoxygenase.

D. Steinberg, J. Witztum, M. Ezaki, 1995, Journal of lipid research.

Clinical trials of antioxidants in atherosclerosis: are we doing the right thing?

D. Steinberg, 1995, The Lancet.

Autoradiographic analysis of the distribution of 125I-tyramine-cellobiose-LDL in atherosclerotic lesions of the WHHL rabbit.

T. Carew, D. Steinberg, M. Rosenfeld, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Antioxidants and atherosclerosis. A current assessment.

D. Steinberg, 1991, Circulation.

Oxidative Modification of Beta‐Very Low Density Lipoprotein: Potential Role in Monocyte Recruitment and Foam Cell Formation

T. Carew, D. Steinberg, S. Parthasarathy, 1989, Arteriosclerosis.

The nature of the epinephrine-induced hyperlipidemia in dogs and its modification by glucose.

D. Steinberg, E. Shafrir, K. Sussman, 1959 .

A Diet-Induced Hypercholesterolemic Murine Model to Study Atherogenesis Without Obesity and Metabolic Syndrome

Andrew C. Li, D. Steinberg, J. Witztum, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Hepatic Catabolism of Low Density Lipoprotein: Mechanisms and Metabolic Consequences

A. Attie, D. Steinberg, R. Pittman, 2007 .

Recognition of oxidatively damaged erythrocytes by a macrophage receptor with specificity for oxidized low density lipoprotein.

D. Steinberg, G. R. Sambrano, S. Parthasarathy, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Some Observations on Hyperlipoproteinemias and their Classification

D. Steinberg, 1972 .

Kinetic studies of plasma free fatty acid and triglyceride metabolism in man.

R. P. Eaton, D. Steinberg, M. Berman, 1969, The Journal of clinical investigation.

Hyperlipoproteinemia in rabbits induced by intravenous administration of fat emulsions and heparin.

M. Hollmann, D. Steinberg, 1968, Journal of atherosclerosis research.

The effect of fatty acid structure on utilization by Ehrlich ascites tumor cells.

D. Steinberg, A. A. Spector, A. Spector, 1967, Cancer research.

Antiatherogenic effect of probucol unrelated to its hypocholesterolemic effect: evidence that antioxidants in vivo can selectively inhibit low density lipoprotein degradation in macrophage-rich fatty streaks and slow the progression of atherosclerosis in the Watanabe heritable hyperlipidemic rabbit.

T. Carew, D. Steinberg, D. Schwenke, 1987, Proceedings of the National Academy of Sciences of the United States of America.

The puzzling ligands for scavenger receptors

D. Steinberg, 2000 .

Is oxidized low density lipoprotein involved in the recruitment and retention of monocyte/macrophages in the artery wall during the initiation of atherosclerosis?

D. Steinberg, S. Parthasarathy, M. Quinn, 1988, Basic life sciences.

D. Steinberg, 2005 .

Underlying mechanisms in atherosclerosis

D. Steinberg, 1981, The Journal of pathology.

D. Steinberg, 1979, Circulation.

Binding, internalization, and degradation of high density lipoprotein by cultured normal human fibroblasts.

D. Steinberg, D. B. Weinstein, N. Miller, 1977, Journal of lipid research.

D. Steinberg, 2022 .

Paradoxical Increase in Rate of Catabolism of Low-Density Lipoproteins after Hepatectomy

James G. Chandler, T. Carew, D. Steinberg, 1974, Science.

Effect of a high carbohydrate diet on apoprotein-B catabolism in man.

D. Steinberg, N. Le, W. Brown, 1981, Metabolism: clinical and experimental.

Turnover and tissue distribution of 125-I-labeled low density lipoprotein in swine and dogs.

T. Carew, D. Steinberg, A. Sniderman, 1975, Journal of lipid research.

Dissociation of the lipid-enzyme complex of hormone-sensitive lipase using high density lipoprotein or apolipoprotein A-I.

C. Drevon, D. Steinberg, J. Khoo, 1980, Biochimica et biophysica acta.

Metabolic studies in an unusual case of asymptomatic familial hypobetalipoproteinemia with hypolphalipoproteinemia and fasting chylomicronemia.

D. Steinberg, J. Albers, D. B. Weinstein, 1979, The Journal of clinical investigation.

A Docking Receptor for HDL Cholesterol Esters

D. Steinberg, 1996, Science.

Uptake of high-density lipoprotein-associated apoprotein A-I and cholesterol esters by 16 tissues of the rat in vivo and by adrenal cells and hepatocytes in vitro.

D. Steinberg, R. Pittman, C. Glass, 1985, The Journal of biological chemistry.

Lysophosphatidylcholine: a chemotactic factor for human monocytes and its potential role in atherogenesis.

D. Steinberg, S. Parthasarathy, M. Quinn, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Studies of Triglyceride Biosynthesis in Homogenates of Adipose Tissue

D. Steinberg, M. Vaughan, S. Margolis, 1961 .

Peroxidase-dependent metal-independent oxidation of low density lipoprotein in vitro: a model for in vivo oxidation?

D. Steinberg, S. Parthasarathy, E. Wieland, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Lipoproteins in normal and atherosclerotic aorta.

D. Steinberg, S. Ylä-Herttuala, J. Witztum, 1990, European heart journal.

Mechanisms Involved in the Uptake and Degradation of Low Density Lipoprotein by the Artery Wall in Vivo a

T. Carew, D. Steinberg, R. Pittman, 1985, Annals of the New York Academy of Sciences.

Hormonal regulation of adipocyte enzymes. The effects of epinephrine and insulin on the control of lipase, phosphorylase kinase, phosphorylase, and glycogen synthase.

D. Steinberg, J. Khoo, S. Mayer, 1973, The Journal of biological chemistry.

The role of plasma free fatty acids in development of fatty liver.

D. Steinberg, A. Karmen, W. Pfaff, 1961, The Journal of clinical investigation.

Role of the pituitary and the adrenal in the mobilization of free fatty acids and lipoproteins.

D. Steinberg, E. Shafrir, K. Sussman, 1960, Journal of lipid research.

Expression of hormone-sensitive lipase mRNA in macrophages.

D. Steinberg, K. Reue, M. Schotz, 1993, Journal of lipid research.

Uptake and degradation of low density lipoprotein by swine arterial smoot muscle cells with inhibition of cholesterol biosynthesis.

T. Carew, D. Steinberg, D. B. Weinstein, 1976, Biochimica et biophysica acta.

Neutral Triglyceride Lipase in Macrophages

D. Steinberg, J. Vance, J. Khoo, 1984, Arteriosclerosis.

CHAPTER 18 – Lipoproteins and Atherosclerosis: A Problem in Cell Biology

D. Steinberg, 1984 .

LDL‐CELL INTERACTION IN VIVO AND IN VITRO *

D. Steinberg, 1980, Annals of the New York Academy of Sciences.

Tissue sites of degradation of native and reductively methylated [14C]sucrose-labeled low density lipoprotein in rats. Contribution of receptor-dependent and receptor-independent pathways.

T. Carew, D. Steinberg, R. Pittman, 1982, The Journal of biological chemistry.

Uptake and degradation of high density lipoprotein: comparison of fibroblasts from normal subjects and from homozygous familial hypercholesterolemic subjects.

D. Steinberg, D. B. Weinstein, N. Miller, 1978, Journal of lipid research.

The Role of the Liver in LDL Catabolism

A. Attie, T. Carew, D. Steinberg, 1980 .

Metabolism of homologous and heterologous lipoproteins by cultured rat and human skin fibroblasts.

C. Drevon, A. Attie, D. Steinberg, 1981, Journal of lipid research.

Lipoprotein Structure and Metabolism: Inhomogeneity, Variability and Species Specificity

D. Steinberg, 1980 .

The secretion of lipoprotein lipase by mononuclear phagocytes

D. Steinberg, J. Witztum, J. Khoo, 1985 .

Regulation von Low- (LDL) und High- (HDL) Density Lipoprotein-Bindungsorten an Fibroblasten von Stoffwechselgesunden und homozygoten familiären Hypercholesterinämikern (HFH)

T. Koschinsky, T. Carew, D. Steinberg, 1977 .

Neutral cholesterol esterase activity in macrophages and its enhancement by cAMP-dependent protein kinase.

D. Steinberg, J. Khoo, E. Mahoney, 1981, Journal of Biological Chemistry.

Studies on the rate of efflux of cholesterol from cultured human skin fibroblasts.

D. Steinberg, T. Parker, R. J. Daniels, 1981, The Journal of biological chemistry.

Interactions of native and modified human low density lipoproteins with human skin fibroblasts.

D. Steinberg, P. Nestel, D. B. Weinstein, 1978, Biochimica et biophysica acta.

Pathogenesis of hyperlipidemias, clues to treatment?

T. Carew, D. Steinberg, D. B. Weinstein, 1975, Advances in experimental medicine and biology.

Enzymatic modification of low density lipoprotein by purified lipoxygenase plus phospholipase A2 mimics cell-mediated oxidative modification.

D. Steinberg, S. Parthasarathy, C. Sparrow, 1988, Journal of lipid research.

Resolution of hormone-sensitive triglyceride/diglyceride lipase from monoglyceride lipase of chicken adipose tissue.

D. Steinberg, J. Khoo, L. Berglund, 1980, The Journal of biological chemistry.

Hormone-sensitive lipase in differentiated 3T3-L1 cells and its activation by cyclic AMP-dependent protein kinase.

D. Steinberg, J. Khoo, M. Kawamura, 1981, Proceedings of the National Academy of Sciences of the United States of America.

[23] Hormone-sensitive triglyceride lipase from rat adipose tissue

D. Steinberg, J. Khoo, 1975 .

Enhanced degradation of trypsin-treated low density lipoprotein by fibroblasts from a patient with homozygous familial hypercholesterolemia.

T. Carew, D. Steinberg, S. Goldstein, 1978, Biochimica et biophysica acta.

CHAPTER 2 – Animal Models of Atherosclerosis

D. Steinberg, 2007 .

Triglyceride, diglyceride, monoglyceride, and cholesterol ester hydrolases in chicken adipose tissue activated by adenosine 3':5'-Monophosphate-dependent protein kinase. Chromatographic resolution and immunochemical differentiation from lipoprotein lipase.

D. Steinberg, J. Khoo, P. Vagelos, 1976, The Journal of biological chemistry.

A comparative study of surface binding of human low density and high density lipoproteins to human fibroblasts: regulation by sterols and susceptibility to proteolytic digestion.

T. Koschinsky, T. Carew, D. Steinberg, 1977, Journal of lipid research.

Low density lipoprotein receptor deficiency in cultured hepatocytes of the WHHL rabbit. Further evidence of two pathways for catabolism of exogenous proteins.

A. Attie, D. Steinberg, Y. Watanabe, 1981, The Journal of biological chemistry.

The Pathogenesis of Atherosclerosis An interpretive history of the cholesterol controversy : part II : the early evidence linking hypercholesterolemia to coronary disease in humans 1

D. Steinberg, 2005 .

Lipoproteins and atherosclerosis: some unanswered questions.

D. Steinberg, 1987, American heart journal.

Macrophages and smooth muscle cells express lipoprotein lipase in human and rabbit atherosclerotic lesions.

D. Steinberg, S. Ylä-Herttuala, J. Witztum, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Binding, Uptake, and Catabolism of Low Density (LDL) and High Density Lipoproteins (HDL) by Cultured Smooth Muscle Cells

T. Koschinsky, T. Carew, D. Steinberg, 1976 .

Subcellular distribution of and epinephrine-induced changes in hormone-sensitive lipase, phosphorylase, and phosphorylase kinase in rat adipocytes.

D. Steinberg, J. Khoo, L. Jarett, 1972, The Journal of biological chemistry.

Gene therapy for cholesterol

R. Havel, D. Steinberg, J. Goldstein, 1994, Nature Genetics.

The essential role of the adrenal cortex in the response of plasma free fatty acids, cholesterol, and phospholipids to epinephrine injection.

D. Steinberg, E. Shafrir, E. Shafrir,, 1960, The Journal of clinical investigation.

The effect of dietary fat on the turnover of cholic acid and on the composition of the biliary bile acids in man.

D. Steinberg, J. Avigan, D. Goodman, 1965, The Journal of clinical investigation.

Polymerase chain reaction-based method for quantifying recruitment of monocytes to mouse atherosclerotic lesions in vivo: enhancement by tumor necrosis factor-alpha and interleukin-1 beta.

C. Glass, D. Steinberg, J. Khoo, 2000, Arteriosclerosis, thrombosis, and vascular biology.

Evidence for the hepatic origin of a canine post‐heparin plasma triglyceride lipase

James G. Chandler, D. Steinberg, A. Sniderman, 1974, FEBS letters.

Partial purification and characterization of hormonesensitive lipase from rat adipose tissue

D. Steinberg, J. Huttunen, J. Ellingboe, 1970 .

6 Hormone-Sensitive Lipase of Adipose Tissue

D. Steinberg, J. Khoo, 1983 .

Reversible protein kinase activation of hormone-sensitive lipase from chicken adipose tissue.

D. Steinberg, J. Khoo, 1974, Journal of lipid research.

HORMONALLY REGULATED ENZYMES IN ADIPOSE TISSUE LINKED TO CYCLIC AMP-DEPENDENT PROTEIN KINASE

D. Steinberg, 1973 .

Partial glyceridase activity of a protein-kinase activatable triglyceride lipase from rat adipose tissue.

D. Steinberg, R. Heller, 1972, Biochimica et biophysica acta.

A second form of hormone-sensitive lipase from rat adipose tissue homogenates.

D. Steinberg, R. Pittman, E. Golanty, 1972, Biochimica et biophysica acta.

Hormonal control of lipolysis in adipose tissue.

D. Steinberg, 1972, Advances in experimental medicine and biology.

Activation and phosphorylation adipose tissue hormone-sensitive lipase by cyclic AMP-dependent protein kinase

D. Steinberg, J. Huttunen, 1971 .

A purified triglyceride lipase, lipoprotein in nature, from rat adipose tissue.

D. Steinberg, J. Huttunen, A. A. Aquino, 1970, Biochimica et biophysica acta.

Hormone-sensitive lipase from chicken adipose tissue including the separation and purification of monoglyceride lipase.

D. Steinberg, J. Khoo, 1981, Methods in enzymology.

Hormone-sensitive lipase of rat adipose tissue: correlation of activity with a protein of molecular weight 84 000.

D. Steinberg, J. Khoo, L. Berglund, 1980, Biochimica et biophysica acta.

Activation of chicken adipose tissue diglyceride lipase by cyclic AMP-dependent protein kinase and its deactivation by purified protein phosphatase.

D. Steinberg, J. Khoo, E. Y. Lee, 1978, Biochemical and biophysical research communications.

Reversible Activation-Deactivation of Hormone-Sensitive Lipase and Observations on its Relation to Lipoprotein Lipase

D. Steinberg, J. Khoo, 1976 .

Activation of hormone-sensitive lipase from adipose tissue by cyclic AMP-dependent protein kinase.

D. Steinberg, J. Khoo, W. Fong, 1972, Biochemical and biophysical research communications.

Protein kinase activation and phosphorylation of a purified hormone-sensitive lipase.

D. Steinberg, J. Huttunen, S. Mayer, 1970, Biochemical and biophysical research communications.

The role of cyclic AMP in activation of hormone-sensitive lipase of adipose tissue.

D. Steinberg, J. Huttunen, 1972, Advances in cyclic nucleotide research.

Effects of prostaglandin E opposing those of catecholamines on blood pressure and on triglyceride breakdown in adipose tissue.

D. Steinberg, P. Nestel, M. Vaughan, 1963, Biochemical pharmacology.

Transport of plasma free fatty acids and triglycerides in man: a theoretical analysis.

D. Steinberg, M. Berman, D. Shames, 1970, The Journal of clinical investigation.

The synthesis of low- and high-density lipoproteins by rat liver in vitro.

D. Steinberg, J. H. Bragdon, C. Radding, 1958, Biochimica et biophysica acta.

UPTAKE OF FREE FATTY ACIDS BY EHRLICH ASCITES TUMOR CELLS.

D. Steinberg, A. A. Spector, A. Tanaka, 1965, The Journal of biological chemistry.

Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro.

D. Steinberg, T. Friedmann, J. Witztum, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Serum Glutamic‐Oxalacetic Transaminase in Coronary Artery Disease: A Review of 201 Cases

D. Steinberg, H. Ticktin, J. M. Evans, 1956, Circulation.

A new approach to determining the rates of recruitment of circulating leukocytes into tissues: application to the measurement of leukocyte recruitment into atherosclerotic lesions.

C. Glass, D. Steinberg, J. Khoo, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Low Density Lipoprotein Oxidation and Its Pathobiological Significance*

Daniel Steinberg, D. Steinberg, 1997, The Journal of Biological Chemistry.

Metabolism of native and of lactosylated human low density lipoprotein: evidence for two pathways for catabolism of exogenous proteins in rat hepatocytes.

A. Attie, D. Steinberg, R. Pittman, 1980, Proceedings of the National Academy of Sciences of the United States of America.

A macrophage receptor for oxidized low density lipoprotein distinct from the receptor for acetyl low density lipoprotein: partial purification and role in recognition of oxidatively damaged cells.

D. Steinberg, G. R. Sambrano, O. Quehenberger, 1995, Proceedings of the National Academy of Sciences of the United States of America.

The mechanism of activation of hormone-sensitive lipase in human adipose tissue.

D. Steinberg, J. Khoo, A. A. Aquino, 1974, The Journal of clinical investigation.

Lipoproteins, Macrophages and Atherosclerosis

D. Steinberg, 1987 .

Cell-induced oxidation of LDL

D. Steinberg, S. Parthasarathy, 1992 .

At last, direct evidence that lipoxygenases play a role in atherogenesis.

D. Steinberg, 1999, The Journal of clinical investigation.

Activatable cholesterol esterase and triacylglycerol lipase activities of rat adrenal and their relationship.

D. Steinberg, R. Pittman, 1977, Biochimica et biophysica acta.

Mobilization of Stored Triglycerides from Macrophages as Free Fatty Acids

D. Steinberg, J. Witztum, J. Khoo, 1984, Arteriosclerosis.

Lipoprotein lipase secretion by human monocytes and rabbit alveolar macrophages in culture.

D. Steinberg, J. Khoo, E. Mahoney, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of cholesterol esterification and biosynthesis in monolayer cultures of normal adult rat hepatocytes.

C. Drevon, D. Steinberg, D. B. Weinstein, 1980, The Journal of biological chemistry.

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.

J L Witztum, T. Carew, D. Steinberg, 1989, The Journal of clinical investigation.

CONSENSUS CONFERENCE ON CHOLESTEROL AND HEART DISEASE

D. Steinberg, I. Jacoby, M. Rose, 1985, The Lancet.

Earlier intervention in the management of hypercholesterolemia: what are we waiting for?

Daniel Steinberg, D. Steinberg, 2010, Journal of the American College of Cardiology.

Lipoprotein Lipase in Cultured Pig Aortic Smooth Muscle Cells

D. Steinberg, J. Vance, J. Khoo, 1982, Arteriosclerosis.

Stimulation of rat liver phosphorylase kinase by micromolar concentrations of Ca2+

D. Steinberg, J. Khoo, 1975, FEBS letters.

Lewis A. Conner Memorial Lecture. Oxidative modification of LDL and atherogenesis.

D. Steinberg, Daniel Steinberg, D. Steinberg, 1997, Circulation.

Oxidized low density lipoprotein--an extreme example of lipoprotein heterogeneity.

D. Steinberg, 1996, Israel journal of medical sciences.

Very low density lipoprotein synthesis and secretion by cultured rat hepatocytes.

D. Steinberg, R. Davis, D. B. Weinstein, 1979, The Journal of biological chemistry.

Low density and high density lipoprotein turnover following portacaval shunt in swine.

T. Carew, D. Steinberg, K. H. Johansen, 1976, Journal of lipid research.

Fatty acid mobilization--mechanisms of regulation and metabolic consequences.

D. Steinberg, 1963, Biochemical Society symposium.

Relationship between fatty acid and glucose utilization in Ehrlich ascites tumor cells.

D. Steinberg, A. A. Spector, A. Spector, 1966, Journal of lipid research.

Cloning and expression in Xenopus oocytes of a mouse homologue of the human acylcoenzyme A: cholesterol acyltransferase and its potential role in metabolism of oxidized LDL.

D. Steinberg, O. Quehenberger, S. Green, 1996, Biochemical and biophysical research communications.

Glyceride biosynthesis, glyceride breakdown and glycogen breakdown in adipose tissue: mechanisms and regulation

D. Steinberg, M. Vaughan, 2011 .

Release of free fatty acids from adipose tissue in vitro in relation to rates of triglyceride synthesis and degradation

D. Steinberg, M. Vaughan, 2011 .

Stimulation of insulin secretion by long-chain free fatty acids. A direct pancreatic effect.

D. Steinberg, W. Greenough, S. Crespin, 1973, The Journal of clinical investigation.

Disorders of Fatty Acids

J. Blass, D. Steinberg, 1973 .

CHAPTER 8 – Inhibition of Cholesterol Biosynthesis, the Discovery of the Statins, and a Revolution in Preventive Cardiology

D. Steinberg, Daniel Steinberg, 2007 .

Role of oxidised low density lipoprotein in atherogenesis.

D. Steinberg, J. Witztum, 1993, British heart journal.

High Blood Cholesterol and Cardiovascular Deaths in Women

A. Gotto, S. Grundy, P. Greenland, 2005 .

Activity of acyl-CoA: cholesterol acyltransferase and 3-hydroxy-3-methylglutaryl-CoA reductase in subfractions of hepatic microsomes enriched with cholesterol.

C. Drevon, D. Steinberg, D. B. Weinstein, 1983, Biochimica et biophysica acta.

CHAPTER 4 – Building the Basic Science Foundation

Daniel Steinberg, D. Steinberg, 2007 .

Radioassay of Carbon-14 in Aqueous Solutions using a Liquid Scintillation Spectrometer

D. Steinberg, 1958, Nature.

Interconvertible enzymes in adipose tissue regulated by cyclic AMP-dependent protein kinase.

D. Steinberg, 1976, Advances in cyclic nucleotide research.

Low density lipoprotein undergoes oxidative modification in vivo.

J L Witztum, T. Carew, D. Steinberg, 1989, Proceedings of the National Academy of Sciences of the United States of America.

The cholesterol wars : the skeptics vs. the preponderance of evidence

Daniel Steinberg, D. Steinberg, 2007 .

The utilization of unesterified palmitate by Ehrlich ascites tumor cells.

D. Steinberg, A. A. Spector, A. Spector, 1965, The Journal of biological chemistry.

Release of free fatty acids from Ehrlich ascites tumor cells.

D. Steinberg, A. A. Spector, A. Spector, 1966, Journal of lipid research.

Acid acylhydrolase deficiency in I-cell disease and pseudo-Hurler polydystrophy.

D. Steinberg, J. Williams, A. Miller, 1979, Biochimica et biophysica acta.

Oxidatively modified low density lipoprotein is a chemoattractant for human T lymphocytes.

D. Steinberg, S. Parthasarathy, H. McMurray, 1993, The Journal of clinical investigation.

CHAPTER 5 – In Search of a Pathogenesis

D. Steinberg, 2007 .

The Pathogenesis of Atherosclerosis An interpretive history of the cholesterol controversy , part III : mechanistically defining the role of hyperlipidemia 1

D. Steinberg, 2005 .

Atherogenesis in perspective: Hypercholesterolemia and inflammation as partners in crime

Daniel Steinberg, D. Steinberg, 2002, Nature Medicine.

Nonenzymatic Glucosylation of Low-Density Lipoprotein Alters Its Biologic Activity

J L Witztum, D. Steinberg, J. Witztum, 1982, Diabetes.

A new approach for assessing cumulative lysosomal degradation of proteins or other macromolecules.

D. Steinberg, R. Pittman, 1978, Biochemical and biophysical research communications.

Enhanced macrophage degradation of low density lipoprotein previously incubated with cultured endothelial cells: recognition by receptors for acetylated low density lipoproteins.

D. Steinberg, E. Mahoney, T. Henriksen, 1981, Proceedings of the National Academy of Sciences of the United States of America.

Lipoproteins and atherosclerosis. A look back and a look ahead.

D. Steinberg, 1983, Arteriosclerosis.

Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

D. Steinberg, S. Ylä-Herttuala, J. Witztum, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Colocalization of 15-lipoxygenase mRNA and protein with epitopes of oxidized low density lipoprotein in macrophage-rich areas of atherosclerotic lesions.

C. Glass, D. Steinberg, S. Ylä-Herttuala, 1990, Proceedings of the National Academy of Sciences of the United States of America.

The oxidative modification hypothesis of atherosclerosis: does it hold for humans?

D. Steinberg, J. Witztum, Daniel Steinberg, 2001, Trends in cardiovascular medicine.

Catecholamine stimulation of fat mobilization and its metabolic consequences.

D. Steinberg, 1966, Pharmacological reviews.

EFFECTS OF THE PROSTAGLANDINS ON HORMONE-INDUCED MOBILIZATION OF FREE FATTY ACIDS.

D. Steinberg, P. Nestel, M. Vaughan, 1964, The Journal of clinical investigation.

P-selectin mediates the interaction of circulating leukocytes with platelets and microvascular endothelium in response to oxidized lipoprotein in vivo.

K. Messmer, T. Carew, H. Lehr, 1994, Laboratory investigation; a journal of technical methods and pathology.

Polymerase Chain Reaction–Based Method for Quantifying Recruitment of Monocytes to Mouse Atherosclerotic Lesions In Vivo Enhancement by Tumor Necrosis Factor-α and Interleukin-1β

Andrew C. Li, C. Glass, D. Steinberg, 2000 .

Mouse Atherosclerotic Lesions In Vivo : Enhancement by Tumor Necrosis Factor-Based Method for Quantifying Recruitment of Monocytes to − Polymerase Chain Reaction

D. Steinberg, J. Khoo, W. Palinski, 2000 .

Turnover and utilization of esterified fatty acids in Ehrlich ascites tumor cells.

D. Steinberg, A. Spector, 1967, The Journal of biological chemistry.

Radioassay of Aqueous Solutions mixed with Solid Crystalline Fluors

D. Steinberg, 1959, Nature.

Macrophage colony-stimulating factor mRNA and protein in atherosclerotic lesions of rabbits and humans.

V. Ord, D. Steinberg, S. Ylä-Herttuala, 1992, The American journal of pathology.

Turnover and tissue sites of degradation of glucosylated low density lipoprotein in normal and immunized rabbits.

J L Witztum, T. Carew, D. Steinberg, 1987, Journal of lipid research.

A comparison of the antiatherogenic effects of probucol and of a structural analogue of probucol in low density lipoprotein receptor-deficient rabbits.

T. Carew, D. Steinberg, J. Fruebis, 1994, The Journal of clinical investigation.

The oxidative modification hypothesis of atherogenesis: an overview.

D. Steinberg, G. Chisolm, Daniel Steinberg, 2000, Free radical biology & medicine.

Surface expression and rapid internalization of macrosialin (mouse CD68) on elicited mouse peritoneal macrophages

D. Steinberg, D. Foster, O. Quehenberger, 2000, Journal of leukocyte biology.

Cell surface expression of mouse macrosialin and human CD68 and their role as macrophage receptors for oxidized low density lipoprotein.

D. Steinberg, O. Quehenberger, V. Terpstra, 1996, Proceedings of the National Academy of Sciences of the United States of America.

The 94- to 97-kDa mouse macrophage membrane protein that recognizes oxidized low density lipoprotein and phosphatidylserine-rich liposomes is identical to macrosialin, the mouse homologue of human CD68.

D. Steinberg, G. R. Sambrano, J. Witztum, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Hypercholesterolemia and inflammation in atherogenesis: two sides of the same coin.

D. Steinberg, 2005, Molecular nutrition & food research.

Human Scavenger Receptor B1 Is Involved in Recognition of Apoptotic Thymocytes by Thymic Nurse Cells

Daniel Steinberg, Tatsuhiko Kodama, Makoto Sato, 2000, Laboratory Investigation.

Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages: role of membrane phosphatidylserine.

D. Steinberg, G. R. Sambrano, Daniel Steinberg, 1995, Proceedings of the National Academy of Sciences of the United States of America.

PROSTAGLANDINS AS ADRENERGIC ANTAGONISTS

D. Steinberg, 1967, Annals of the New York Academy of Sciences.

Cholesterol and cardiovascular disease: current perspectives. Introduction and overview.

D. Steinberg, 1987, Circulation.

A Novel Mechanism by which High Density Lipoprotein Selectively Delivers Cholesterol Esters to the Liver

D. Steinberg, R. Pittman, 1986 .

Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy: part I Published, JLR Papers in Press, April 21, 2004. DOI 10.1194/jlr.R400003-JLR200 11 Based in part on The Cholesterol Wars, a book in preparation.

D. Steinberg, 2004, Journal of Lipid Research.

CHAPTER 3 – Hypercholesterolemia and Atherosclerosis in Humans: Causally Related?

D. Steinberg, 2007 .

Evidence mandating earlier and more aggressive treatment of hypercholesterolemia.

Daniel Steinberg, C. Glass, D. Steinberg, 2008, Circulation.

Lipoproteins and atherogenesis. Current concepts.

J L Witztum, D. Steinberg, J. Witztum, 1990, JAMA.

Oxidative Modification of LDL and Atherogenesis

D. Steinberg, 1998 .

Monoclonal antibodies against LDL further enhance macrophage uptake of LDL aggregates.

J L Witztum, F. Pio, D. Steinberg, 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

Thematic The Pathogenesis of Atherosclerosis An interpretive history of the cholesterol controversy: part I 1

D. Steinberg, 2004 .

Lipoproteins and the pathogenesis of atherosclerosis.

D. B. Zilversmit, R. Mahley, T. Carew, 1989, Circulation.

The role of oxidized low-density lipoproteins in the pathogenesis of atherosclerosis.

J L Witztum, D. Steinberg, J. Witztum, 1992, Annual review of medicine.

Effects of oleate-rich and linoleate-rich diets on the susceptibility of low density lipoprotein to oxidative modification in mildly hypercholesterolemic subjects.

D. Steinberg, P. Reaven, S. Parthasarathy, 1993, The Journal of clinical investigation.

Very low density lipoprotein secretion by cultured rat hepatocytes. Inhibition by albumin and other macromolecules.

D. Steinberg, R. Davis, D. B. Weinstein, 1980, The Journal of biological chemistry.

Receptor-mediated catabolism of homologous low density lipoproteins in cultured pig hepatocytes.

D. Steinberg, D. B. Weinstein, S. Pangburn, 1981, The Journal of biological chemistry.

Hormone-sensitive lipase of adipose tissue.

D. Steinberg, J. Khoo, 1977, Federation proceedings.

Steinberg Antioxidants and Atherosclerosis 1421 i Cells Growth and change of phenotype ARTERY WALL

D. Steinberg, 2005 .

Rabbit and human atherosclerotic lesions contain IgG that recognizes epitopes of oxidized LDL.

D. Steinberg, S. Ylä-Herttuala, W. Palinski, 1994, Arteriosclerosis and thrombosis : a journal of vascular biology.

The case for treating hypercholesterolemia at an earlier age: moving toward consensus.

S. Grundy, D. Steinberg, 2012, Journal of the American College of Cardiology.

Hormonal regulation of lipase, phosphorylase, and glycogen synthase in adipose tissue.

D. Steinberg, J. Khoo, R. Miller, 1975, Advances in cyclic nucleotide research.

Radiolabeled sucrose covalently linked to protein. A device for quantifying degradation of plasma proteins catabolized by lysosomal mechanisms.

A. Attie, D. Steinberg, R. Pittman, 1979, The Journal of biological chemistry.

THE FATE OF PLASMA FREE FATTY ACIDS AND THEIR EFFECTS ON TISSUE METABOLISM.

D. Steinberg, 1964, Metabolism: clinical and experimental.

A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.

D. Steinberg, S. Parthasarathy, E. Wieland, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Activation of hormone-sensitive lipase and phosphorylase kinase by purified cyclic GMP-dependent protein kinase.

D. Steinberg, J. Khoo, G. Gill, 1977, Proceedings of the National Academy of Sciences of the United States of America.

ATP-dependent and cyclic AMP-dependent activation of rat adipose tissue lipase by protein kinase from rabbit skeletal muscle.

D. Steinberg, J. Huttunen, S. Mayer, 1970, Proceedings of the National Academy of Sciences of the United States of America.

Evidence that the lipid moiety of oxidized low density lipoprotein plays a role in its interaction with macrophage receptors.

D. Steinberg, V. Terpstra, D. A. Bird, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Tissue sites of catabolism of albumin in rabbits.

T. Carew, D. Steinberg, S. Yedgar, 1983, The American journal of physiology.

Transport of Cholesterol and Cholesterol Esters by HDL

D. Steinberg, 1987 .

Synthesis and Secretion of Very Low Density Lipoprotein by Cultured Rat Hepatocytes

Roger A. Davis, D. Steinberg, D. B. Weinstein, 1980 .

Macrophages lacking scavenger receptor A show a decrease in binding and uptake of acetylated low-density lipoprotein and of apoptotic thymocytes, but not of oxidatively damaged red blood cells.

D. Steinberg, V. Terpstra, D Steinberg, 1997, Proceedings of the National Academy of Sciences of the United States of America.

The Cholesterol Wars: The Cholesterol Skeptics vs the Preponderance of Evidence

D. Steinberg, 2008 .

Hormone-sensitive triglyceride lipase from rat adipose tissue.

D. Steinberg, J. Khoo, 1975, Methods in Enzymology.

α-Hydroxy fatty acids in hereditary ataxic polyneuritis (Refsum's disease)

J. Blass, D. Steinberg, J. Avigan, 1969 .

The medical evaluation of the internationally adopted child

D. Steinberg, R. Sperling, Zachary Belnavis, 2021, Adoption & Fostering.

Oxidized low density lipoprotein is chemotactic for human monocytes

D. Steinberg, S. Parthasarathy, M. Quinn, 1986 .

Essential role of phospholipase A 2 activity in endothelial cell-induced modification of low density lipoprotein ( atherosclerosis / foam celis / macrophages / lipid peroxides )

D. Steinberg, J. Witztum, U. Steinbrecher, 2003 .

CHAPTER 1 – Overview

D. Steinberg, 2007 .

The Rationale for Initiating Treatment of Hypercholesterolemia in Young Adulthood

D. Steinberg, 2012, Current Atherosclerosis Reports.

Failure of Alpha‐Phenylbutyrate and Beta‐Phenylvalerate in Treatment of Hypercholesterolemia

D. Steinberg, D. Fredrickson, 1957, Circulation.

Oxidative modification of LDL: comparison between cell-mediated and copper-mediated modification.

D. Steinberg, L. Fong, S. Parthasarathy, 1990, European heart journal.

Cell surface expression of mouse macrosialin and human CD 68 and their role as macrophage receptors for oxidized low density lipoprotein

D. Steinberg, O. Quehenberger, V. Terpstra, 1996 .

Studies on the metabolism of 3, 3-dimethyl phenylmyrtstic acid, a nonoxidizable fatty acid analogue.

D. Steinberg, D. Goodman, 1958, The Journal of biological chemistry.

The hydrolysis of cholesterol esters in plasma lipoproteins by hormone-sensitive cholesterol esterase from adipose tissue.

C. Drevon, D. Steinberg, J. Khoo, 1979, The Journal of biological chemistry.

Activation and phosphorylation of purified adipose tissue hormone-sensitive lipase by cyclic AMP-dependent protein kinase.

D. Steinberg, J. Huttunen, 1971, Biochimica et biophysica acta.

Role of oxidized low density lipoprotein in atherogenesis.

D. Steinberg, J. Witztum, 1991, The Journal of clinical investigation.

Steinberg Antioxidants and Atherosclerosis 1421 i Cells Growth and change of phenotype ARTERY WALL

D. Steinberg, 2005 .

Evidence mandating earlier and more aggressive treatment of hypercholesterolemia.

C. Glass, D. Steinberg, J. Witztum, 2008, Circulation.

Probucol inhibits oxidative modification of low density lipoprotein.

S. Young, D. Steinberg, J. Witztum, 1986, The Journal of clinical investigation.

A Diet-Induced Hypercholesterolemic Murine Model to Study Atherogenesis Without Obesity and Metabolic Syndrome

Andrew C. Li, D. Steinberg, J. Witztum, 2007, Arteriosclerosis, thrombosis, and vascular biology.

Role of the Low Density Lipoprotein Receptor in Penetration of Low Density Lipoprotein into Rabbit Aortic Wall

T. Carew, D. Steinberg, O. Wiklund, 1985, Arteriosclerosis.

Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy, part V: The discovery of the statins and the end of the controversy 1 Published, JLR Papers in Press, April 3, 2006.

D. Steinberg, 2006, Journal of Lipid Research.

Hypercholesterolemia and Atherosclerosis: Pathogenesis and Prevention

D. Steinberg, J. Olefsky, 1987 .

Scavenger receptor type B, class 1 (SR-B1) as a receptor for oxidized low density lipoprotein (OxLDL)

D. Steinberg, J. Witztum, O. Quehenberger, 2000 .

The pathogenesis of atherosclerosis. An interpretive history of the cholesterol controversy, part IV: the 1984 coronary primary prevention trial ends it--almost.

D. Steinberg, 2006, Journal of lipid research.

Thematic review series: The Pathogenesis of Atherosclerosis. An interpretive history of the cholesterol controversy, part IV: The 1984 Coronary Primary Prevention Trial ends it—almost1

D. Steinberg, 2006, Journal of Lipid Research.