P. Williams

发表

Bacterial cell-to-cell communication: sorry, can't talk now - gone to lunch!

K. Winzer, K. Hardie, P. Williams, 2002, Current opinion in microbiology.

Early development and quorum sensing in bacterial biofilms

P. Williams, J. King, J. Ward, 2003, Journal of mathematical biology.

The Pseudomonas aeruginosa quinolone signal molecule overcomes the cell density‐dependency of the quorum sensing hierarchy, regulates rhl‐dependent genes at the onset of stationary phase and can be produced in the absence of LasR

S. Diggle, K. Winzer, P. Williams, 2003, Molecular microbiology.

Quinolones: from Antibiotics to Autoinducers

S. Diggle, P. Williams, S. Heeb, 2022 .

Quorum Quenching by an N-Acyl-Homoserine Lactone Acylase from Pseudomonas aeruginosa PAO1

S. Diggle, P. Williams, L. Otten, 2006, Infection and Immunity.

Comprehensive profiling of N-acylhomoserine lactones produced by Yersinia pseudotuberculosis using liquid chromatography coupled to hybrid quadrupole–linear ion trap mass spectrometry

P. Williams, D. Barrett, C. Ortori, 2007, Analytical and bioanalytical chemistry.

A cell-cell communication signal integrates quorum sensing and stress response.

P. Williams, Changqing Chang, Lian-Hui Zhang, 2013, Nature chemical biology.

Physicochemical surface properties ofKlebsiella pneumoniae

P. Williams, S. Merino, J. Tomás, 2005, Current Microbiology.

Biosensor-based assays for PQS, HHQ and related 2-alkyl-4-quinolone quorum sensing signal molecules

S. Diggle, P. Williams, M. Cámara, 2007, Nature Protocols.

Detection of 2-alkyl-4-quinolones using biosensors.

S. Diggle, P. Williams, M. Cámara, 2011, Methods in molecular biology.

Manipulation of quorum sensing regulation in Pseudomonas fluorescens NCIMB 10586 to increase mupirocin production

Christopher M Thomas, P. Williams, G. Campbell, 2011, Applied Microbiology and Biotechnology.

Turnover of quorum sensing signal molecules modulates cross-kingdom signalling.

I. Joint, P. Williams, M. Cámara, 2009, Environmental microbiology.

Combinatorial discovery of polymers resistant to bacterial attachment

Robert Langer, Ying Mei, Andrew L. Hook, 2012, Nature Biotechnology.

Corrigendum: Combinatorial discovery of polymers resistant to bacterial attachment

Daniel G. Anderson, R. Langer, M. Alexander, 2014, Nature Biotechnology.

Conservation, Surface Exposure, and In Vivo Expression of the Frp Family of Iron-Regulated Cell Wall Proteins in Staphylococcus aureus

P. Williams, J. Morrissey, P. Hill, 2002, Infection and Immunity.

Quorum sensing regulates dpsA and the oxidative stress response in Burkholderia pseudomallei.

S. Diggle, P. Williams, Putthapoom Lumjiaktase, 2006, Microbiology.

Uromodulin mutations causing familial juvenile hyperuricaemic nephropathy lead to protein maturation defects and retention in the endoplasmic reticulum.

P. Rorsman, C. Antignac, P. Williams, 2009, Human molecular genetics.

The Pseudomonas aeruginosa global regulator MvaT specifically binds to the ptxS upstream region and enhances ptxS expression.

S. Diggle, P. Williams, M. Cámara, 2004, Microbiology.

The MexGHI-OpmD multidrug efflux pump controls growth, antibiotic susceptibility and virulence in Pseudomonas aeruginosa via 4-quinolone-dependent cell-to-cell communication.

S. Diggle, P. Williams, M. Cámara, 2005, Microbiology.

Biosensors for qualitative and semiquantitative analysis of quorum sensing signal molecules.

P. Williams, D. Barrett, M. Cámara, 2014, Methods in molecular biology.

Regulatory roles of spnT, a novel gene located within transposon TnTIR.

P. Williams, S. Swift, P. Soo, 2006, Biochemical and biophysical research communications.

All subtypes of the cytotoxin VacA adsorb to the surface of Helicobacter pylori post-secretion.

K. Hardie, P. Williams, P. O'shea, 2005, Journal of medical microbiology.

Electrostatic sensor for identifying interactions between peptides and bacterial membranes.

K. Hardie, P. Williams, P. O'shea, 2003, Molecular immunology.

Synthesis and biotransformation of 2-alkyl-4(1H)-quinolones by recombinant Pseudomonas putida KT2440

P. Williams, S. Fetzner, S. R. Chhabra, 2011, Applied Microbiology and Biotechnology.

Structural Basis for Native Agonist and Synthetic Inhibitor Recognition by the Pseudomonas aeruginosa Quorum Sensing Regulator PqsR (MvfR)

P. Williams, J. Emsley, S. Heeb, 2013, PLoS pathogens.

Modelling and Prediction of Bacterial Attachment to Polymers

Robert Langer, David A. Winkler, Morgan R. Alexander, 2014 .

A dual biosensor for 2-alkyl-4-quinolone quorum-sensing signal molecules.

S. Diggle, P. Williams, M. Cámara, 2007, Environmental microbiology.

2-Alkyl-4(1 H )-Quinolone Signalling in Pseudomonas aeruginosa

S. Diggle, P. Williams, S. Heeb, 2010 .

The galactophilic lectin, LecA, contributes to biofilm development in Pseudomonas aeruginosa.

S. Diggle, K. Winzer, P. Williams, 2006, Environmental microbiology.

Quinolones: from antibiotics to autoinducers

S. Diggle, P. Williams, S. Heeb, 2010, FEMS microbiology reviews.

The regulation of biofilm development by quorum sensing in Aeromonas hydrophila.

P. Williams, S. Swift, C. Keevil, 2002, Environmental microbiology.

Direct detection of N-acylhomoserine lactones in cystic fibrosis sputum.

Miguel Cámara, P. Williams, A. Knox, 2002, FEMS microbiology letters.

VanT, a Homologue of Vibrio harveyi LuxR, Regulates Serine, Metalloprotease, Pigment, and Biofilm Production in Vibrio anguillarum

P. Williams, M. Cámara, D. Milton, 2002, Journal of bacteriology.

The Aeromonas hydrophila LuxR homologue AhyR regulates the N-acyl homoserine lactone synthase, AhyI positively and negatively in a growth phase-dependent manner.

P. Williams, S. Swift, M. J. Lynch, 2004, FEMS microbiology letters.

Functional complementation of E. coli secD and secG mutants by Helicobacter pylori homologues.

K. Hardie, P. Williams, N. Fitchen, 2003, FEMS microbiology letters.

N-Acylhomoserine Lactones Antagonize Virulence Gene Expression and Quorum Sensing in Staphylococcus aureus

Philip Hill, P. Williams, M. Cámara, 2006, Infection and Immunity.

Functional genetic analysis reveals a 2-Alkyl-4-quinolone signaling system in the human pathogen Burkholderia pseudomallei and related bacteria.

S. Diggle, K. Winzer, P. Williams, 2006, Chemistry & biology.

Controlling infection by tuning in and turning down the volume of bacterial small-talk.

P. Williams, M. Cámara, A. Hardman, 2002, The Lancet. Infectious diseases.

The Pseudomonas aeruginosa sensor RetS switches type III and type VI secretion via c-di-GMP signalling.

P. Williams, S. Heeb, A. Filloux, 2011, Environmental microbiology.

Global regulation of virulence and the stress response by CsrA in the highly adapted human gastric pathogen Helicobacter pylori

Michael P. Messenger, D. Ussery, P. Williams, 2003, Molecular microbiology.

The LuxR family protein SpnR functions as a negative regulator of N‐acylhomoserine lactone‐dependent quorum sensing in Serratia marcescens

Simon Swift, Hsin-Chih Lai, P. Williams, 2002, Molecular microbiology.

N-Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-Dependent Manner during Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa

Steve Atkinson, Edwin A. Yates, P. Williams, 2002, Infection and Immunity.

Simultaneous quantitative profiling of N-acyl-l-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MS

Miguel Cámara, David A Barrett, K. Hardie, 2011, Analytical and bioanalytical chemistry.

The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment.

Miguel Cámara, S. Diggle, P. Williams, 2007, Chemistry & biology.

High throughput methods applied in biomaterial development and discovery.

Robert Langer, Andrew L Hook, Martyn C Davies, 2010, Biomaterials.

Bacterial transferrin receptors — structure, function and contribution to virulence

P. Williams, Paul Williams, E. Griffiths, 2004, Medical Microbiology and Immunology.

Functional interplay between the Yersinia pseudotuberculosis YpsRI and YtbRI quorum sensing systems modulates swimming motility by controlling expression of flhDC and fliA

P. Williams, R. Sockett, M. Cámara, 2008, Molecular microbiology.

LuxS-dependent quorum sensing in Porphyromonas gingivalis modulates protease and haemagglutinin activities but is not essential for virulence.

Miguel Cámara, Kim R Hardie, Klaus Winzer, 2002, Microbiology.

Pathogen espionage: multiple bacterial adrenergic sensors eavesdrop on host communication systems

Klaus Winzer, K. Winzer, P. Williams, 2013, Molecular microbiology.

Cystic Fibrosis Isolates of Pseudomonas aeruginosa Retain Iron-Regulated Antimicrobial Activity against Staphylococcus aureus through the Action of Multiple Alkylquinolones

Jace W. Jones, Angela T. Nguyen, Amanda G. Oglesby-Sherrouse, 2016, Front. Microbiol..

Conflict of interest and signal interference lead to the breakdown of honest signaling

Sam P. Brown, A. Griffin, S. West, 2015, Evolution; international journal of organic evolution.

The structure and mechanism of methanol dehydrogenase.

C. Anthony, P. Williams, 2003, Biochimica et biophysica acta.

A distinctive dual‐channel quorum‐sensing system operates in Vibrio anguillarum

P. Williams, M. Cámara, D. Milton, 2004, Molecular microbiology.

Quorum sensing and the cell-cell communication dependent regulation of gene expression in pathogenic and non-pathogenic bacteria

P. Williams, A. Hardman, G. Stewart, 1998, Antonie van Leeuwenhoek.

Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling system.

P. Williams, N. Minton, G. Carter, 2005, Journal of medical microbiology.

Transcriptomic analysis reveals a global alkyl-quinolone-independent regulatory role for PqsE in facilitating the environmental adaptation of Pseudomonas aeruginosa to plant and animal hosts

P. Williams, S. Heeb, K. Rumbaugh, 2010, Environmental microbiology.

4-quinolone signalling in Pseudomonas aeruginosa: old molecules, new perspectives.

S. Diggle, P. Williams, M. Cámara, 2006, International journal of medical microbiology : IJMM.

Rapid necrotic killing of polymorphonuclear leukocytes is caused by quorum-sensing-controlled production of rhamnolipid by Pseudomonas aeruginosa.

P. Williams, T. B. Rasmussen, N. Høiby, 2007, Microbiology.

Quorum Sensing in Yersinia enterocolitica Controls Swimming and Swarming Motility

P. Williams, R. Sockett, M. Cámara, 2006, Journal of bacteriology.

N-Acylhomoserine lactone quorum-sensing molecules are modified and degraded by Rhodococcus erythropolis W2 by both amidolytic and novel oxidoreductase activities.

P. Williams, M. Cámara, P. Oger, 2005, Microbiology.

Cell-cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover.

J. M. Dow, Lisa C. Crossman, P. Williams, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Advancing the Quorum in Pseudomonas aeruginosa: MvaT and the Regulation of N-Acylhomoserine Lactone Production and Virulence Gene Expression

Stephen P. Diggle, Klaus Winzer, S. Diggle, 2002, Journal of bacteriology.

The RssAB Two-Component Signal Transduction System in Serratia marcescens Regulates Swarming Motility and Cell Envelope Architecture in Response to Exogenous Saturated Fatty Acids

P. Williams, S. Swift, S. Ho, 2005, Journal of bacteriology.

Interkingdom crosstalk

P. Williams, M. Karavolos, C. Khan, 2011, Virulence.

Negative Regulation of Violacein Biosynthesis in Chromobacterium violaceum

P. Williams, M. Cámara, V. Venturi, 2017, Front. Microbiol..

Positive Control of Swarming, Rhamnolipid Synthesis, and Lipase Production by the Posttranscriptional RsmA/RsmZ System in Pseudomonas aeruginosa PAO1

G. Pessi, P. Williams, S. Heeb, 2004, Journal of bacteriology.

LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone.

Kim R Hardie, Klaus Winzer, R. Linforth, 2002, Microbiology.

Quorum sensing in Vibrio cholerae

P. Williams, M. Cámara, D. Milton, 2002, Nature Genetics.

A novel quorum-sensing system regulating the multicellular behaviour in Serratia marcescens

P. Williams, S. Swift, K. Luh, 2002 .

Combinatorial discovery of novel polymers resistant to bacterial attachment

Andrew L. Hook, Daniel G. Anderson, R. Langer, 2012 .

The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa.

P. Williams, T. Kajander, M. Cámara, 2008, Microbiology.

HosA, a Member of the SlyA Family, Regulates Motility in Enteropathogenic Escherichia coli

P. Williams, M. Ferrándiz, K. Bishop, 2005, Infection and Immunity.

Biofilm Formation in Pseudomonas aeruginosa: Fimbrial cup Gene Clusters Are Controlled by the Transcriptional Regulator MvaT

S. Diggle, S. Lory, P. Williams, 2004, Journal of bacteriology.

Long- and short-chain plant-produced bacterial N-acyl-homoserine lactones become components of phyllosphere, rhizosphere, and soil.

P. Williams, M. Savka, R. Fray, 2006, Molecular plant-microbe interactions : MPMI.

Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria

P. Williams, D. Grierson, R. Fray, 1999, Nature Biotechnology.

Discovery of Novel Materials with Broad Resistance to Bacterial Attachment Using Combinatorial Polymer Microarrays

Robert Langer, Andrew L Hook, Martyn C Davies, 2013, Advanced materials.

Biofilm Development on Caenorhabditis elegans by Yersinia Is Facilitated by Quorum Sensing-Dependent Repression of Type III Secretion

P. Williams, B. Wren, M. Cámara, 2011, PLoS pathogens.

Disruption of quorum sensing in seawater abolishes attraction of zoospores of the green alga Ulva to bacterial biofilms.

I. Joint, P. Williams, M. Cámara, 2005, Environmental microbiology.

N-Acylhomoserine lactone-mediated quorum sensing: a twist in the tail and a blow for host immunity.

P. Williams, S. R. Chhabra, M. Cooley, 2008, Chemistry & biology.

The Staphylococcal Ferritins Are Differentially Regulated in Response to Iron and Manganese and via PerR and Fur

P. Williams, J. Morrissey, A. Cockayne, 2004, Infection and Immunity.

Thermally Switchable Polymers Achieve Controlled Escherichia coli Detachment

Andrew L. Hook, Daniel G. Anderson, R. Langer, 2014, Advanced healthcare materials.

Glutamate-haem ester bond formation is disfavoured in flavocytochrome P450 BM3: characterization of glutamate substitution mutants at the haem site of P450 BM3.

K. Fisher, P. Williams, A. Munro, 2010, The Biochemical journal.

Escherichia coli gets the message

K. Winzer, P. Williams, 2003, Nature Medicine.

High throughput discovery of thermo-responsive materials using water contact angle measurements and time-of-flight secondary ion mass spectrometry

Andrew L. Hook, M. Alexander, P. Williams, 2012, Surface and interface analysis : SIA.

A LuxRI‐family regulatory system controls excision and transfer of the Mesorhizobium loti strain R7A symbiosis island by activating expression of two conserved hypothetical genes

P. Williams, D. Barrett, S. Heeb, 2009, Molecular microbiology.

N-acyl homoserine lactones are degraded via an amidolytic activity in Comamonas sp. strain D1

P. Williams, M. Cámara, P. Oger, 2007, Archives of Microbiology.

Mathematical modelling of the agr operon in Staphylococcus aureus

P. Williams, J. King, A. Koerber, 2010, Journal of mathematical biology.

Bacterial conversations: talking, listening and eavesdropping. An introduction

Ian Joint, I. Joint, P. Williams, 2007, Philosophical Transactions of the Royal Society B: Biological Sciences.

LC-MS/MS quantitative analysis of quorum sensing signal molecules.

P. Williams, D. Barrett, C. Ortori, 2014, Methods in molecular biology.

A mathematical investigation of the effects of inhibitor therapy on three putative phosphorylation cascades governing the two-component system of the agr operon.

Sara Jabbari, P. Williams, J. King, 2010, Mathematical biosciences.

High throughput methods applied in biomaterial development and discovery.

Andrew L. Hook, Daniel G. Anderson, R. Langer, 2010, Biomaterials.

The PA4204 gene encodes a periplasmic gluconolactonase (PpgL) which is important for fitness of Pseudomonas aeruginosa.

P. Williams, T. Kajander, M. Cámara, 2008, Microbiology.

N-Acylhomoserine Lactones Undergo Lactonolysis in a pH-, Temperature-, and Acyl Chain Length-Dependent Manner during Growth of Yersinia pseudotuberculosis and Pseudomonas aeruginosa

P. Williams, M. Cámara, S. Atkinson, 2002, Infection and Immunity.