E. Ross

发表

Overview of the Alliance for Cellular Signaling

Temple F. Smith, D. Botstein, A. Arkin, 2002, Nature.

G Protein-Coupled Receptors

E. Ross, T. Kokkola, 2019 .

PDZ domain proteins: Scaffolds for signaling complexes

R. Ranganathan, E. Ross, 1997, Current Biology.

GTPase-Activating Proteins (GAPs) for Heterotrimeric G Proteins

Jun Wang, E. Ross, P. Chidiac, 2020 .

Chapter 11 G Protein-Coupled Receptors: Structure and Function of Signal-Transducing Proteins

E. Ross, E. Parker, 1990 .

Reconstitution of the Beta-Adrenergic Receptor and Its Biochemical Functions

E. Ross, 1991 .

Mammalian phospholipase C.

E. Ross, Ganesh Kadamur, 2013, Annual review of physiology.

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

A. Gilman, E. Ross, P. Sternweis, 1987, The Journal of biological chemistry.

Assay of protein in the presence of high concentrations of sulfhydryl compounds.

E. Ross, G. Schatz, Elliott M. Ross, 1973, Analytical biochemistry.

Viral hijack of receptors

E. Ross, 1990, Nature.

Role of the β-Adrenergic Receptor in the Regulation of Adenylate Cyclase

A. Gilman, E. Ross, M. Smigel, 1984 .

Alteration in the protein components of catecholamine-sensitive adenylate cyclase during maturation of rat reticulocytes.

E. Ross, A. Larner, 1981, The Journal of biological chemistry.

Functional activation of beta-adrenergic receptors by thiols in the presence or absence of agonists.

E. Ross, S. Pedersen, 1985, The Journal of biological chemistry.

Beta-adrenergic receptors display intramolecular disulfide bridges in situ: analysis by immunoblotting and functional reconstitution.

E. Ross, C. Malbon, S. George, 1988, Molecular pharmacology.

Coordinating Speed and Amplitude in G-Protein Signaling

E. Ross, 2008, Current Biology.

Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells.

M. Cobb, E. Ross, E. Wauson, 2015, Molecular endocrinology.

Gαq and Phospholipase C-β: Turn On, Turn Off, and Do It Fast

E. Ross, 2011, Science Signaling.

Inhibition of brain Gz GAP and other RGS proteins by palmitoylation of G protein alpha subunits.

E. Ross, J. Wang, Y. Tu, 1997, Science.

Spinophilin regulates Ca 2 + signalling by binding the N-terminal domain of RGS 2 and the third intracellular loop of G-protein-coupled receptors

P. Greengard, P. Allen, S. Muallem, 2005 .

A GTPase-activating protein for the G protein Galphaz. Identification, purification, and mechanism of action.

E. Ross, Y. Tu, J. Wang, 1997, The Journal of biological chemistry.

The N-terminal Domain of RGS4 Confers Receptor-selective Inhibition of G Protein Signaling*

S. Muallem, E. Ross, P. Chidiac, 1998, The Journal of Biological Chemistry.

Coordinating Speed and Amplitude in G-Protein Signaling

E. Ross, 2008, Current Biology.

RGSZ1 and Ret RGS: two of several splice variants from the gene RGS20.

E. Ross, D. A. Sierra, S. A. Barker, 2001, Genomics.

Mastoparan, a peptide toxin from wasp venom, mimics receptors by activating GTP-binding regulatory proteins (G proteins).

E. Ross, T. Nakajima, T. Higashijima, 1988, The Journal of biological chemistry.

GTPase activity of the stimulatory GTP-binding regulatory protein of adenylate cyclase, Gs. Accumulation and turnover of enzyme-nucleotide intermediates.

E. Ross, D. Brandt, Elliott M. Ross, 1985, The Journal of biological chemistry.

beta-Adrenergic receptor: ligand binding properties and the interaction with adenylyl cyclase.

M. Maguire, A. Gilman, E. Ross, 1977, Advances in cyclic nucleotide research.

Article WNK1 Promotes PIP 2 Synthesis to Coordinate Growth Factor and GPCR-G q Signaling

E. Ross, S. Cha, Chou-Long Huang, 2011 .

WNK1 Promotes PIP2 Synthesis to Coordinate Growth Factor and GPCR-Gq Signaling

E. Ross, S. Cha, Chou-Long Huang, 2011, Current Biology.

Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq*

M. Simon, I. Fraser, E. Ross, 2010, The Journal of Biological Chemistry.

Carboxyl-terminal Domains in the Avian β1-Adrenergic Receptor That Regulate Agonist-promoted Endocytosis (*)

E. Ross, J. Perkins, E. Parker, 1995, The Journal of Biological Chemistry.

Erratum: Carboxyl-terminal domains in the avian β1-adrenergic receptor that regulate agonist-promoted endocytosis (Journal of Biological Chemistry (1995) 270 (6482-6487))

E. Ross, J. Perkins, M. Nunnally, 1995 .

A truncation mutation in the avian beta-adrenergic receptor causes agonist-induced internalization and GTP-sensitive agonist binding characteristic of mammalian receptors.

E. Ross, J. Perkins, E. A. Murphy, 1990, The Journal of biological chemistry.

Radioimmunoassay of digitonin.

J. W. Fleming, G. Brooker, E. Ross, 1982, Biochimica et biophysica acta.

Selectivity of the beta-adrenergic receptor among Gs, Gi's, and Go: assay using recombinant alpha subunits in reconstituted phospholipid vesicles.

E. Ross, R. Rubenstein, M. Linder, 1991, Biochemistry.

Selectivity of the @-Adrenergic Receptor among G , , Gi ’ s , and Go : Assay Using Recombinant a ! Subunits in Reconstituted Phospholipid Vesicles ?

E. Ross, R. Rubenstein, M. Linder, 2022 .

Phosphatidylcholine-promoted interaction of the catalytic and regulatory proteins of adenylate cyclase.

E. Ross, 1982, Journal of Biological Chemistry.

Guanine Nucleotide Exchange Factors

E. Ross, 2002 .

Functional reconstitution of beta-adrenergic receptors and the stimulatory GTP-binding protein of adenylate cyclase.

E. Ross, S. Pedersen, Steen E. Pedersen, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Adenylate cyclase permanently uncoupled from hormone receptors in a novel variant of S49 mouse lymphoma cells.

A. Gilman, E. Ross, T. Haga, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Binding of Regulator of G Protein Signaling (RGS) Proteins to Phospholipid Bilayers

E. Ross, Y. Tu, J. Woodson, 2001, The Journal of Biological Chemistry.

Carboxyl-terminal Fragments of Phospholipase C-β1 with Intrinsic Gq GTPase-activating Protein (GAP) Activity*

E. Ross, R. Paulssen, J. Woodson, 1996, The Journal of Biological Chemistry.

Reconstitution of catecholamine-stimulated binding of guanosine 5'-O-(3-thiotriphosphate) to the stimulatory GTP-binding protein of adenylate cyclase.

C. W. Scott, E. Ross, T. Asano, 1984, Biochemistry.

Twists and turns on G-protein signalling pathways

E. Ross, 1992, Current Biology.

Twists and turns on G-protein signalling pathways G proteins are components of a sophisticated signal-processing system in plasma membranes, involving branched circuits, molecular 'AND' and 'BUT NOT' gates and adjustable temporal responses.

E. Ross, 1992 .

The binding of activated Gαq to phospholipase C-β exhibits anomalous affinity

E. Ross, A. Gershenson, Punya Navaratnarajah, 2017, The Journal of Biological Chemistry.

Activation of the inhibitory GTP-binding protein of adenylate cyclase, Gi, by beta-adrenergic receptors in reconstituted phospholipid vesicles.

T. Katada, A. Gilman, E. Ross, 1984, The Journal of biological chemistry.

The hydrophobic tryptic core of the beta-adrenergic receptor retains Gs regulatory activity in response to agonists and thiols.

E. Ross, R. Rubenstein, S. Wong, 1987, The Journal of biological chemistry.

Spinophilin regulates Ca2+ signalling by binding the N-terminal domain of RGS2 and the third intracellular loop of G-protein-coupled receptors

P. Greengard, P. Allen, S. Muallem, 2005, Nature Cell Biology.

Quench-flow kinetic measurement of individual reactions of G-protein-catalyzed GTPase cycle.

E. Ross, S. Mukhopadhyay, 2002, Methods in enzymology.

Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G13 Pathway*

D. Decamp, I. Fraser, R. Taussig, 2007, Journal of Biological Chemistry.

Gs regulation of endosome fusion suggests a role for signal transduction pathways in endocytosis.

I. Nishimoto, E. Ross, M. Colombo, 1994, The Journal of biological chemistry.

Foundations and Future of Molecular Pharmacology

B. Sykes, P. Taylor, P. Sigler, 1995 .

Reconstitution of receptors and G proteins in phospholipid vesicles.

E. Ross, R. Cerione, 1991, Methods in enzymology.

Phospholipase C-β1 Directly Accelerates GTP Hydrolysis by Gαq and Acceleration Is Inhibited by Gβγ Subunits*

E. Ross, P. Chidiac, 1999, The Journal of Biological Chemistry.

Kinetic control of guanine nucleotide binding to soluble Gαq

V. Markin, E. Ross, P. Chidiac, 1999 .

Rapid binding of guanosine 5'-O-(3-thiotriphosphate) to an apparent complex of beta-adrenergic receptor and the GTP-binding regulatory protein Gs.

E. Ross, D. C. May, 1988, Biochemistry.

Cytochrome c1 of bakers' yeast. I. Isolation and properties.

E. Ross, G. Schatz, 1976, The Journal of biological chemistry.

Cytochrome c1 of bakers' yeast. II. Synthesis on cytoplasmic robosomes and influence of oxygen and heme on accumulation of the apoprotein.

E. Ross, G. Schatz, 1976, The Journal of biological chemistry.

Purification of the regulatory component of adenylate cyclase.

A. Gilman, E. Ross, P. Sternweis, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Biochemical properties of hormone-sensitive adenylate cyclase.

A. Gilman, E. Ross, 1980, Annual review of biochemistry.

Dynamic Regulation of RGS2 Suggests a Novel Mechanism in G-Protein Signaling and Neuronal Plasticity

C. Barnes, P. Worley, A. Gilman, 1998, The Journal of Neuroscience.

Reconstitution of hormone-sensitive adenylate cyclase activity with resolved components of the enzyme.

A. Gilman, E. Ross, A. Howlett, 1978, The Journal of biological chemistry.

Resolution of some components of adenylate cyclase necessary for catalytic activity.

A. Gilman, E. Ross, A. G. Gilman, 1977, The Journal of biological chemistry.

Hormone-Sensitive Adenylate Cyclase: Identity, Function, and Regulation of the Protein Components

E. Ross, S. Pedersen, V. Florio, 1983 .

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins.

E M Ross, E. Ross, T. Wilkie, 2000, Annual review of biochemistry.

Signal sorting and amplification through G protein-coupled receptors

Elliott M. Ross, E. Ross, 1989, Neuron.

Relationship between the beta-adrenergic receptor and adenylate cyclase.

M. Maguire, A. Gilman, E. Ross, 1977, The Journal of biological chemistry.

The N-terminal Domain of RGS 4 Confers Receptor-selective Inhibition of G Protein Signaling

S. Muallem, E. Ross, P. Chidiac, 1998 .

Catecholamine-stimulated GTPase cycle. Multiple sites of regulation by beta-adrenergic receptor and Mg2+ studied in reconstituted receptor-Gs vesicles.

E. Ross, D. Brandt, 1986, The Journal of biological chemistry.

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

E. Ross, P. Sternweis, J. Blank, 1992, The Journal of biological chemistry.

Functional Importance of the Amino Terminus of G(*)

A. Gilman, E. Ross, J. Hepler, 1996, Journal of Biological Chemistry.

A Gs-selective analog of the receptor-mimetic peptide mastoparan binds to Gs alpha in a kinked helical conformation.

E. Ross, M. Sukumar, T. Higashijima, 1997, Biochemistry.

ATP-dependent regulation of flagellar adenylylcyclase in gametes of Chlamydomonas reinhardtii.

W. Snell, E. Ross, Y. Zhang, 1991, The Journal of biological chemistry.

Biological Signal Transduction

K. Wirtz, E. Ross, 1991, NATO ASI Series.

Heterotrimeric G Proteins

E. Ross, 2002 .

Homer 2 tunes G protein–coupled receptors stimulus intensity by regulating RGS proteins and PLCβ GAP activities

P. Worley, S. Muallem, M. Dehoff, 2003, The Journal of cell biology.

Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway

R. Neve, E. Ross, D. Howland, 2018, Proceedings of the National Academy of Sciences.

GTP-Binding Proteins

E. Ross, 2002 .

The Carboxyl-terminal Anchorage Domain of the Turkey β1-Adrenergic Receptor Is Encoded by an Alternatively Spliced Exon (*)

E. Ross, Jun Wang, 1995, The Journal of Biological Chemistry.

Rapid GTP binding and hydrolysis by G(q) promoted by receptor and GTPase-activating proteins.

E M Ross, S Mukhopadhyay, E. Ross, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Amino Acids Regulate mTORC1 by an Obligate Two-step Mechanism*

M. Cobb, E. Ross, J. Dyachok, 2016, The Journal of Biological Chemistry.

Phospholipase C-β1 is a GTPase-activating protein for Gq/11, its physiologic regulator

E. Ross, J. Blank, S. Rhee, 1992, Cell.

Regulation of the catalytic component of adenylate cyclase. Potentiative interaction of stimulatory ligands and 2',5'-dideoxyadenosine.

E. Ross, V. Florio, 1983, Molecular pharmacology.

Gβγ Inhibits Gα GTPase-activating Proteins by Inhibition of Gα-GTP Binding during Stimulation by Receptor*

E. Ross, Y. Tu, Wei Tang, 2006, Journal of Biological Chemistry.

Regulation of phospholipase C-beta1 by Gq and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation.

E M Ross, E. Ross, G. Biddlecome, 1996, The Journal of biological chemistry.

RGSZ1, a G(z)-selective rgs protein in brain: Structure, membrane association, regulation by Gα(z) phosphorylation, and relationship to a G(z) gtpase-activating protein subfamily

R. Aebersold, Jun Wang, E. Ross, 1998 .

Expression of human muscarinic cholinergic receptors in tobacco

E. Ross, N. Chua, J. Mu, 1997, Plant Molecular Biology.

Chimeric muscarinic cholinergic: beta-adrenergic receptors that activate Gs in response to muscarinic agonists.

E. Ross, E. Parker, S. Wong, 1990, The Journal of biological chemistry.

Synergistic Activation of Phospholipase C-β3 by Gαq and Gβγ Describes a Simple Two-State Coincidence Detector

E. Ross, Ganesh Kadamur, F. Philip, 2010, Current Biology.

Regulation of G-protein activation by mastoparans and other cationic peptides.

E. Ross, T. Higashijima, 1994, Methods in enzymology.

RGSZ 1 and Ret RGS : Two of Several Splice Variants from the Gene RGS 20

Jun Wang, E. Ross, D. A. Sierra, 2001 .

RGSZ1, a Gz-selective RGS Protein in Brain

R. Aebersold, E. Ross, T. Kozasa, 1998, The Journal of Biological Chemistry.

Coordinate Regulation of G Protein Signaling via Dynamic Interactions of Receptor and GAP

Wei Tang, Marc Turcotte, Elliott M. Ross, 2008, PLoS Comput. Biol..

Mutations in the Carboxyl-terminal Domain of Phospholipase C-β1 Delineate the Dimer Interface and a Potential GαqInteraction Site*

L. Kinch, E. Ross, R. Paulssen, 2002, The Journal of Biological Chemistry.

G protein GTPase-activating proteins: regulation of speed, amplitude, and signaling selectivity.

E. Ross, 1995, Recent progress in hormone research.

Regulation of the M1 muscarinic receptor-Gq-phospholipase C-beta pathway by nucleotide exchange and GTP hydrolysis.

E. Ross, G. Berstein, 1993, Life sciences.

Chimeric muscarinic cholinergic:beta-adrenergic receptors that are functionally promiscuous among G proteins.

E. Ross, S. Wong, Elliott M. Ross, 1994, The Journal of biological chemistry.

Structural Determinants for Phosphatidic Acid Regulation of Phospholipase C-β1*

A. Gomes, C. Arana, E. Ross, 2006, Journal of Biological Chemistry.

Quantitative assays for GTPase-activating proteins.

E. Ross, 2002, Methods in enzymology.

Phosphorylation-regulated Inhibition of the Gz GTPase-activating Protein Activity of RGS Proteins by Synapsin I*

E. Ross, Y. Tu, J. Woodson, 2003, Journal of Biological Chemistry.

Reciprocal Signaling between Heterotrimeric G Proteins and the p21-stimulated Protein Kinase*

J. Frost, Jun Wang, M. Cobb, 1999, The Journal of Biological Chemistry.

Guanosine triphosphatase-activating proteins for heterotrimeric G-proteins.

E. Ross, G. Biddlecome, Y. Tu, 1998, Advances in pharmacology.

Reconstitution of catecholamine-stimulated adenylate cyclase activity using three purified proteins.

A. Gilman, E. Ross, M. Smigel, 1985, The Journal of biological chemistry.

STRUCTURE, MEMBRANE ASSOCIATION, REGULATION BY Gaz PHOSPHORYLATION, AND RELATIONSHIP TO AG z GTPase-ACTIVATING PROTEIN SUBFAMILY*

R. Aebersold, Jun Wang, E. Ross, 1998 .

Reconstitution of catecholamine-sensitive adenylate cyclase activity: interactions of solubilized components with receptor-replete membranes.

A. Gilman, E. Ross, 1977, Proceedings of the National Academy of Sciences of the United States of America.

Regulating G protein-coupled receptors by topological inversion

E. Ross, B. Denard, Jin Ye, 2019, eLife.

Palmitoylation of a Conserved Cysteine in the Regulator of G Protein Signaling (RGS) Domain Modulates the GTPase-activating Activity of RGS4 and RGS10*

E. Ross, C. Slaughter, Y. Tu, 1999, The Journal of Biological Chemistry.

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein α-subunit

S. Sprang, E. Ross, Pilong Li, 2004 .

Regulation of Phospholipase C-1 by G and m1 Muscarinic Cholinergic Receptor

Elliott M. Ross, E. Ross, G. Biddlecome, 1996, The Journal of Biological Chemistry.

Modulation of the affinity and selectivity of RGS protein interaction with G alpha subunits by a conserved asparagine/serine residue.

A. Gilman, B. Posner, E. Ross, 1999, Biochemistry.

Reconstitution of catecholamine-stimulated guanosinetriphosphatase activity.

E. Ross, T. Asano, D. Brandt, 1983, Biochemistry.

Reconstitution of the regulatory functions of beta-adrenergic receptors.

E. Ross, T. Asano, D. Brandt, 1984, Advances in experimental medicine and biology.

Reconstitution of beta-adrenergic receptors into phospholipid vesicles: restoration of [125I]iodohydroxybenzylpindolol binding to digitonin-solubilized receptors.

J. W. Fleming, E. Ross, 1980, Journal of cyclic nucleotide research.

Activation Biosensor for G Protein-Coupled Receptors: A FRET-Based m1 Muscarinic Activation Sensor That Regulates Gq

Elliott M. Ross, E. Ross, Seungwoo Chang, 2012, PLoS ONE.

Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits.

E. Ross, P. Chidiac, 1999, The Journal of biological chemistry.

Mapping of the mastoparan-binding site on G proteins. Cross-linking of [125I-Tyr3,Cys11]mastoparan to Go.

E. Ross, T. Higashijima, 1991, The Journal of biological chemistry.

The catecholamine binding site of the beta-adrenergic receptor is formed by juxtaposed membrane-spanning domains.

C. Slaughter, E. Ross, A. Ruoho, 1988, The Journal of biological chemistry.

Selective Regulation of G Proteins by Cell Surface Receptors

E. Ross, 1989 .

G Protein-Coupled Receptors: Structural Basis of Selective Signaling

E. Ross, 1991 .

Uncoupling conformational change from GTP hydrolysis in a heterotrimeric G protein alpha-subunit.

S. Sprang, E. Ross, Pilong Li, 2004, Proceedings of the National Academy of Sciences of the United States of America.

DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi

E. Ross, Jingyi Zhao, Vincent DiGiacomo, 2020, The Journal of Biological Chemistry.

Intrinsic Pleckstrin Homology (PH) Domain Motion in Phospholipase C-β Exposes a Gβγ Protein Binding Site*

E. Ross, Ganesh Kadamur, 2016, The Journal of Biological Chemistry.

Coordinating Speed and Amplitude in G-Protein Signaling

E. Ross, Elliot M. Ross, 2008, Current Biology.

Functional Domains in the β-Adrenergic Receptor

E. Ross, R. Rubenstein, T. Higashijima, 1988 .

Mutations in the carboxyl-terminal domain of phospholipase C-beta 1 delineate the dimer interface and a potential Galphaq interaction site.

L. Kinch, E. Ross, R. Paulssen, 2002, Journal of Biological Chemistry.

Erratum: Regulation of phospholipase C-β1 by G(q) and m1 muscarinic cholinergic receptor. Steady-state balance of receptor-mediated activation and GTPase-activating protein-promoted deactivation (Journal of Biological Chemistry (1996) 271 (7999-8007))

Elliott M. Ross, E. Ross, G. Biddlecome, 1996 .

Catecholamine-stimulated guanosine 5'-O-(3-thiotriphosphate) binding to the stimulatory GTP-binding protein of adenylate cyclase: kinetic analysis in reconstituted phospholipid vesicles.

E. Ross, T. Asano, 1984, Biochemistry.

Effect of Al3+ plus F- on the catecholamine-stimulated GTPase activity of purified and reconstituted Gs.

E. Ross, D. Brandt, 1986, Biochemistry.

Regulation of Gi and Go by mastoparan, related amphiphilic peptides, and hydrophobic amines. Mechanism and structural determinants of activity.

E. Ross, T Higashijima, J. Burnier, 1990, The Journal of biological chemistry.

Physical separation of the catalytic and regulatory proteins of hepatic adenylate cyclase.

E. Ross, 1981, The Journal of biological chemistry.

Differential Regulation of ERK1/2 and mTORC1 Through T1R1/T1R3 in MIN6 Cells.

M. Cobb, E. Ross, E. Wauson, 2015, Molecular endocrinology.