P. Sternweis

发表

Overview of the Alliance for Cellular Signaling

Temple F. Smith, D. Botstein, A. Arkin, 2002, Nature.

Deciphering Signaling Outcomes from a System of Complex Networks

M. Simon, I. Fraser, Madhusudan Natarajan, 2009, Science Signaling.

p115 Rho GTPase activating protein interacts with MEKK1

C. Wells, M. Cobb, P. Sternweis, 2002, Journal of cellular physiology.

Regulation of polyphosphoinositide-specific phospholipase C activity by purified Gq.

P C Sternweis, P. Sternweis, J. Hepler, 1991, Science.

Chromatographic resolution and immunologic identification of the alpha 40 and alpha 41 subunits of guanine nucleotide-binding regulatory proteins from bovine brain.

A. Gilman, P. Sternweis, S. Mumby, 1988, The Journal of biological chemistry.

The epsilon subunit of Escherichia coli coupling factor 1 is required for its binding to the cytoplasmic membrane.

P. Sternweis, 1978, The Journal of biological chemistry.

Characterization of the inhibitory (epsilon) subunit of the proton-translocating adenosine triphosphatase from Escherichia coli.

P. Sternweis, J. Smith, 1980, Biochemistry.

Purification and properties of reconstitutively active and inactive adenosinetriphosphatase from Escherichia coli.

P. Sternweis, L. Heppel, M. Futai, 1974, Proceedings of the National Academy of Sciences of the United States of America.

The effect of activating ligands on the intrinsic fluorescence of guanine nucleotide-binding regulatory proteins.

A. Gilman, E. Ross, P. Sternweis, 1987, The Journal of biological chemistry.

Relationships within the family of GTP-binding proteins isolated from bovine central nervous system.

P. Sternweis, M. Applebury, D. Roof, 1985, The Journal of biological chemistry.

Subunit specific antisera to the Escherichia coli ATP synthase: effects on ATPase activity, energy transduction, and enzyme assembly.

P. Sternweis, J. Smith, 1982, Archives of biochemistry and biophysics.

Structure of the rgRGS domain of p115RhoGEF

S. Sprang, C. Wells, P. Sternweis, 2001, Nature Structural Biology.

Purification and characterization of recombinant G16 alpha from Sf9 cells: activation of purified phospholipase C isozymes by G-protein alpha subunits.

M. Simon, A. Gilman, P. Sternweis, 1993, Proceedings of the National Academy of Sciences of the United States of America.

The G protein-channel connection

P. Sternweis, lok-Hou Pang, 1990, Trends in Neurosciences.

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium*

M. Simon, D. Decamp, I. Fraser, 2008, Journal of Biological Chemistry.

The regulatory component of adenylate cyclase. Purification and properties of the turkey erythrocyte protein.

A. Dromerick, P. Sternweis, E. Hanski, 1981, The Journal of biological chemistry.

Reconstitution of catecholamine-sensitive adenylate cyclase. Reconstitution of the uncoupled variant of the S40 lymphoma cell.

A. Gilman, P. Sternweis, 1979, The Journal of biological chemistry.

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution, activity, and properties of the 35,000-dalton (beta) subunit.

A. Gilman, P. Sternweis, J. Northup, 1983, The Journal of biological chemistry.

Reconstitution of catecholamine-sensitive adenylate cyclase. Association of a regulatory component of the enzyme with membranes containing the catalytic protein and beta-adrenergic receptors.

A. Gilman, P. Sternweis, A. Howlett, 1979, The Journal of biological chemistry.

The active role of ? in signal transduction

P. Sternweis, 1994 .

Phospholipase D activity is required for suppression of yeast phosphatidylinositol transfer protein defects.

Z. Xie, P. Sternweis, M. Fang, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Requirements for cholera toxin-dependent ADP-ribosylation of the purified regulatory component of adenylate cyclase.

R. Kahn, A. Gilman, P. Sternweis, 1982, The Journal of biological chemistry.

Resolved Phospholipase D Activity Is Modulated by Cytosolic Factors Other than Arf (*)

G. Bokoch, P. Sternweis, H. Brown, 1995, The Journal of Biological Chemistry.

Purification and properties of the regulatory component (G/F) of adenylate cyclase.

P. Sternweis, E. Hanski, J. Northup, 1981, Advances in cyclic nucleotide research.

The regulatory component of adenylate cyclase from uncoupled S49 lymphoma cells differs in charge from the wild type protein.

P. Sternweis, J. Northup, J. Garrison, 1980, The Journal of biological chemistry.

The regulatory component of adenylate cyclase. Purification and properties.

A. Gilman, P. Sternweis, J. Northup, 1981, The Journal of biological chemistry.

Zymosan activates protein kinase A via adenylyl cyclase VII to modulate innate immune responses during inflammation.

P. Sternweis, Lily I. Jiang, Jennifer E. Wang, 2013, Molecular immunology.

Photoaffinity labeling of two rat liver plasma membrane proteins with [32P]gamma-azidoanilido GTP in response to vasopressin. Immunologic identification as alpha subunits of the Gq class of G proteins.

P. Sternweis, R. Wange, J. Exton, 1991, The Journal of biological chemistry.

Mechanisms of muscarinic receptor action on Go in reconstituted phospholipid vesicles.

P. Sternweis, V. Florio, 1989, The Journal of biological chemistry.

Lipid Modifications of G Protein Subunits MYRISTOYLATION OF Go, INCREASES ITS AFFINITY FOR By*

J. Gordon, A. Gilman, P. Sternweis, 2001 .

The LPP1 and DPP1 Gene Products Account for Most of the Isoprenoid Phosphate Phosphatase Activities inSaccharomyces cerevisiae *

G. Carman, P. Sternweis, Xiaoming Chen, 1999, The Journal of Biological Chemistry.

Hormone signalling via G-protein: regulation of phosphatidylinositol 4,5-bisphosphate hydrolysis by Gq.

P. Sternweis, A. Smrcka, S. Gutowski, 1992, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

Purification of unique alpha subunits of GTP-binding regulatory proteins (G proteins) by affinity chromatography with immobilized beta gamma subunits.

P. Sternweis, I. Pang, Iok Hou Pang, 1990, The Journal of biological chemistry.

Isolation of the alpha subunits of GTP-binding regulatory proteins by affinity chromatography with immobilized beta gamma subunits.

P. Sternweis, I. Pang, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Use of a cAMP BRET Sensor to Characterize a Novel Regulation of cAMP by the Sphingosine 1-Phosphate/G13 Pathway*

D. Decamp, I. Fraser, R. Taussig, 2007, Journal of Biological Chemistry.

Regions on Adenylyl Cyclase VII Required for Selective Regulation by the G13 Pathway

P. Sternweis, Lily I. Jiang, Jennifer E. Wang, 2013, Molecular Pharmacology.

Purification and characterization of the alpha subunit of G13.

R. T. Miller, P. Sternweis, W. Singer, 1994, The Journal of biological chemistry.

Purification of membrane attachment and inhibitory subunits of the proton translocating adenosine triphosphatase from Escherichia coli.

P. Sternweis, J. Smith, 1977, Biochemistry.

Subunits of the bacterial proton‐pump ATPase: A synopsis

P. Sternweis, L. Heppel, J. Smith, 1976, Journal of cellular physiology.

Partial purification of active delta and epsilon subunits of the membrane ATPase from escherichia coli.

P. Sternweis, L. Heppel, J. Smith, 1975, Journal of supramolecular structure.

LigandsShort-Term Stimulation with 33 Single Expression Changes in Response to Analysis of the Major Patterns of B Cell Gene

R. Scheuermann, Melvin I. Simon, Sangdun Choi, 2004 .

Regulation of hormone-sensitive GTP-dependent regulatory proteins by chloride.

P. Sternweis, T. Higashijima, K. M. Ferguson, 1987, The Journal of biological chemistry.

Purification of the regulatory component of adenylate cyclase.

A. Gilman, E. Ross, P. Sternweis, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Regulation of phospholipase C by G proteins.

P. Sternweis, A. Smrcka, 1992, Trends in biochemical sciences.

Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins

J. Rothstein, P. Sternweis, H. Federoff, 2001, Nature.

Differential G protein—mediated coupling of neurotransmitter receptors to Ca2+ channels in rat dorsal root ganglion neurons in vitro

P. Sternweis, Richard J. Miller, D. Ewald, 1989, Neuron.

A global analysis of cross-talk in a mammalian cellular signalling network

Madhusudan Natarajan, Rama Ranganathan, Robert C. Hsueh, 2006, Nature Cell Biology.

Partial Purification and Characterization of Arf-sensitive Phospholipase D from Porcine Brain (*)

R. Kahn, P. Sternweis, H. Brown, 1995, The Journal of Biological Chemistry.

Guanine nucleotide-binding protein Go-induced coupling of neuropeptide Y receptors to Ca2+ channels in sensory neurons.

R. Miller, P. Sternweis, D. Ewald, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

P. Sternweis, J. Robishaw, 1984, The Journal of biological chemistry.

Influence of gamma subunit prenylation on association of guanine nucleotide-binding regulatory proteins with membranes.

A. Gilman, P. Sternweis, S. Mumby, 1992, Molecular biology of the cell.

Reconstitution of agonist-stimulated phosphatidylinositol 4,5-bisphosphate hydrolysis using purified m1 muscarinic receptor, Gq/11, and phospholipase C-beta 1.

E. Ross, P. Sternweis, J. Blank, 1992, The Journal of biological chemistry.

Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D.

P C Sternweis, H A Brown, P. Sternweis, 1997, Annual review of biochemistry.

Ribozyme- and siRNA-mediated suppression of RGS-containing RhoGEF proteins.

R. Neubig, P. Sternweis, Min Liu, 2004, Methods in enzymology.

Antibodies to the αq subfamily of guanine nucleotide-binding regulatory protein α subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones

M. Simon, P. Sternweis, A. Smrcka, 1991 .

Aluminum: a requirement for activation of the regulatory component of adenylate cyclase by fluoride.

A. Gilman, P. Sternweis, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Purification from Sf9 cells and characterization of recombinant Gq alpha and G11 alpha. Activation of purified phospholipase C isozymes by G alpha subunits.

M. Simon, A. Gilman, Melvin I. Simon, 1993, The Journal of biological chemistry.

Direct stimulation of the guanine nucleotide exchange activity of p115 RhoGEF by Galpha13.

P C Sternweis, A. Gilman, P. Sternweis, 1998, Science.

Regulation of purified subtypes of phosphatidylinositol-specific phospholipase C beta by G protein alpha and beta gamma subunits.

P C Sternweis, P. Sternweis, A. Smrcka, 1993, The Journal of biological chemistry.

The purified alpha subunits of Go and Gi from bovine brain require beta gamma for association with phospholipid vesicles.

P. Sternweis, 1986, The Journal of biological chemistry.

The Monomeric G-Proteins Rac1 and/or Cdc42 Are Required for the Inhibition of Voltage-Dependent Calcium Current by Bradykinin

J. Frost, P. Sternweis, F. Belardetti, 1997, The Journal of Neuroscience.

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits

P. Hawkins, L. Stephens, P. Sternweis, 1994, Cell.

A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein beta gamma subunits.

P. Hawkins, L. Stephens, P. Sternweis, 1994, Cell.

Regulation of Rho guanine nucleotide exchange factors by G proteins.

Shahab M. Danesh, A. Carter, P. Sternweis, 2007, Advances in protein chemistry.

Regulation of Phospholipase D by Protein Kinase C Is Synergistic with ADP-ribosylation Factor and Independent of Protein Kinase Activity (*)

P. Sternweis, H. Brown, Xuejun Jiang, 1996, The Journal of Biological Chemistry.

Thrombin and Lysophosphatidic Acid Receptors Utilize Distinct rhoGEFs in Prostate Cancer Cells*

Min Liu, Tohru Kozasa, Richard R Neubig, 2004, Journal of Biological Chemistry.

Mapping the Gα13 Binding Interface of the rgRGS Domain of p115RhoGEF*

S. Sprang, C. Wells, P. Sternweis, 2003, The Journal of Biological Chemistry.

Mechanisms for Reversible Regulation between G13 and Rho Exchange Factors*

J. Rothstein, C. Wells, P. Sternweis, 2002, The Journal of Biological Chemistry.

Functional characterization of p115 RhoGEF.

C. Wells, P. Sternweis, Xuejun Jiang, 2002, Methods in enzymology.

Identification of Potential Mechanisms for Regulation of p115 RhoGEF through Analysis of Endogenous and Mutant Forms of the Exchange Factor*

C. Wells, P. Sternweis, G. Bollag, 2001, The Journal of Biological Chemistry.

Purification of αq/11 from Brain

P. Sternweis, A. Smrcka, 1993 .

G proteins in signal transduction: the regulation of phospholipase C.

P. Sternweis, A. Smrcka, 1993, Ciba Foundation symposium.

G protein gamma subunits contain a 20-carbon isoprenoid.

P. Casey, A. Gilman, P. Sternweis, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands1

Richard H. Scheuermann, Zhen Yan, Shankar Subramaniam, 2004, The Journal of Immunology.

The Regulatory Component of Adenylate Cyclase

A. Dromerick, P. Sternweis, J. Northup, 1981 .

Lipid modifications of G protein subunits. Myristoylation of Go alpha increases its affinity for beta gamma.

J. Gordon, A. Gilman, P. Sternweis, 1991, The Journal of biological chemistry.

Distinct Roles of Adenylyl Cyclase VII in Regulating the Immune Responses in Mice

Dorothy Yuan, Eva L. Sadat, P. Sternweis, 2010, The Journal of Immunology.

Effects of Mg2+ and the beta gamma-subunit complex on the interactions of guanine nucleotides with G proteins.

A. Gilman, P. Sternweis, M. Smigel, 1987, The Journal of biological chemistry.

Secondary PDZ domain-binding site on class B plexins enhances the affinity for PDZ–RhoGEF

P. Sternweis, Xuewu Zhang, C. Brautigam, 2015, Proceedings of the National Academy of Sciences.

Reconstitution of resolved muscarinic cholinergic receptors with purified GTP-binding proteins.

P. Sternweis, V. Florio, 1985, The Journal of biological chemistry.

The subunits of the stimulatory regulatory component of adenylate cyclase. Resolution of the activated 45,000-dalton (alpha) subunit.

A. Gilman, P. Sternweis, J. Northup, 1983, The Journal of biological chemistry.

The Purified Q Subunits of Go and Gi from Bovine Brain Require p r for Association with Phospholipid Vesicles”

P. Sternweis, 2001 .

Evidence that phospholipase D mediates ADP ribosylation factor- dependent formation of Golgi coated vesicles

M. Roth, P. Sternweis, H. Brown, 1996, The Journal of cell biology.

Phospholipase D is present on Golgi-enriched membranes and its activation by ADP ribosylation factor is sensitive to brefeldin A.

M. Roth, P. Sternweis, H. Brown, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Bradykinin modulates potassium and calcium currents in neuroblastoma hybrid cells via different pertussis toxin-insensitive pathways

P. Sternweis, F. Belardetti, S. Gutowski, 1994, Neuron.

The G protein G13 mediates inhibition of voltage-dependent calcium current by bradykinin

P. Sternweis, F. Belardetti, S. Gutowski, 1994, Neuron.

RhoA Binds to the Amino Terminus of MEKK1 and Regulates Its Kinase Activity*

M. Cobb, P. Sternweis, E. Gallagher, 2004, Journal of Biological Chemistry.

A1 adenosine receptors of bovine brain couple to guanine nucleotide-binding proteins Gi1, Gi2, and Go.

P. Sternweis, I. Pang, J. Linden, 1991, The Journal of biological chemistry.

Suppression of LPS-Induced TNF-α Production in Macrophages by cAMP Is Mediated by PKA-AKAP95-p105

M. Simon, I. Fraser, P. Sternweis, 2009, Science Signaling.

Regulation of cAMP Responses by the G12/13 Pathway Converges on Adenylyl Cyclase VII*

I. Fraser, P. Sternweis, Lily I. Jiang, 2008, Journal of Biological Chemistry.

Stimulation of phospholipase D by ADP-ribosylation factor.

P. Sternweis, H. Brown, 1995, Methods in enzymology.

Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF.

Shahab M. Danesh, S. Sprang, P. Sternweis, 2008, Structure.

Structure of the p115RhoGEF rgRGS domain–Gα13/i1 chimera complex suggests convergent evolution of a GTPase activator

S. Sprang, P. Sternweis, Zhe Chen, 2005, Nature Structural &Molecular Biology.

Antibodies to the alpha q subfamily of guanine nucleotide-binding regulatory protein alpha subunits attenuate activation of phosphatidylinositol 4,5-bisphosphate hydrolysis by hormones.

P. Sternweis, M. Simon, A. Smrcka, 1991, The Journal of biological chemistry.

CHAPTER 161 – Phospholipase D

P. Sternweis, 2003 .

Assays and characterization of mammalian phosphatidylinositol 4,5-bisphosphate-sensitive phospholipase D.

P. Sternweis, Xuejun Jiang, S. Gutowski, 2002, Methods in enzymology.

The C Terminus of Mammalian Phospholipase D Is Required for Catalytic Activity*

P. Sternweis, Mu-ya Liu, S. Gutowski, 2001, The Journal of Biological Chemistry.

The role of lipid signaling in constitutive membrane traffic.

M. Roth, P. Sternweis, Michael G. Roth, 1997, Current opinion in cell biology.

Modulation of a GEF switch: Autoinhibition of the intrinsic guanine nucleotide exchange activity of p115‐RhoGEF

S. Sprang, P. Sternweis, Liang Guo, 2011, Protein science : a publication of the Protein Society.

Modeling species-specific diacylglycerol dynamics in the RAW 264.7 macrophage.

H. Callender, D. Decamp, M. Horn, 2010, Journal of theoretical biology.

Activation of p115-RhoGEF Requires Direct Association of Gα13 and the Dbl Homology Domain*

S. Sprang, P. Sternweis, Liang Guo, 2012, The Journal of Biological Chemistry.

Activated RhoA Binds to the Pleckstrin Homology (PH) Domain of PDZ-RhoGEF, a Potential Site for Autoregulation*♦

Zhe Chen, S. Sprang, P. Sternweis, 2010, The Journal of Biological Chemistry.

Regulated Localization Is Sufficient for Hormonal Control of Regulator of G Protein Signaling Homology Rho Guanine Nucleotide Exchange Factors (RH-RhoGEFs)*

A. Carter, P. Sternweis, S. Gutowski, 2014, The Journal of Biological Chemistry.

p115 RhoGEF, a GTPase activating protein for Gα12 and Gα13

A. Gilman, P. Sternweis, G. Bollag, 1998 .

p115 RhoGEF, a GTPase activating protein for Galpha12 and Galpha13.

P C Sternweis, A. Gilman, P. Sternweis, 1998, Science.

The Role Of P115 Rhogef In The Rho Mediated Effects Of Lpa On The Actin Cytoskeleton.

C. Wells, P. Sternweis, H. Arnott, 1999, Microscopy and Microanalysis.

Crystal structures of the PH domains from Lbc family of RhoGEFs bound to activated RhoA GTPase

P. Sternweis, S. Gutowski, Zhe Chen, 2018, Data in brief.

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLC3 to Regulate Intracellular

M. Simon, D. Decamp, I. Fraser, 2008 .

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium*

M. Simon, D. Decamp, I. Fraser, 2008, Journal of Biological Chemistry.

Regulation of Camp Responses by the G 12/13 Pathway Converges on Adenylyl Cyclase Vii* from the Alliance for Cellular Signaling

P. Sternweis, Lily I. Jiang, Richard Davis, 2022 .

Direct regulation of p190RhoGEF by activated Rho and Rac GTPases.

P. Sternweis, C. Brautigam, S. Gutowski, 2018, Journal of structural biology.

Characterization of the purified membrane attachment (beta) subunit of the proton translocating adenosine triphosphatase from Escherichia coli.

P. Sternweis, J. Smith, 1977, Biochemistry.

Restoration of coupling factor activity to Escherichia coli ATPase missing the delta subunit.

P. Sternweis, J. Smith, 1975, Biochemical and biophysical research communications.