W. Seaman

发表

Overview of the Alliance for Cellular Signaling

Temple F. Smith, D. Botstein, A. Arkin, 2002, Nature.

A single lentiviral vector platform for microRNA-based conditional RNA interference and coordinated transgene expression

M. Simon, I. Fraser, W. Seaman, 2006, Proceedings of the National Academy of Sciences.

Iron Uptake Mediated by Binding of H-Ferritin to the TIM-2 Receptor in Mouse Cells

M. Willingham, W. Seaman, F. Torti, 2011, PloS one.

Binding and uptake of H-ferritin are mediated by human transferrin receptor-1

W. Seaman, F. Torti, S. Torti, 2010, Proceedings of the National Academy of Sciences.

Microscale Immune Studies Laboratory.

Howland D. T. Jones, Julia N. Kaiser, Thomas D. Perroud, 2009 .

Cocaine increases natural killer cell activity.

W. Seaman, A. Chuntharapai, C. Van Dyke, 1986, The Journal of clinical investigation.

An autosomal dominant locus, Nka, mapping to the Ly-49 region of a rat natural killer (NK) gene complex, controls NK cell lysis of allogeneic lymphocytes

W. Seaman, J. Ryan, E. Dissen, 1996, The Journal of experimental medicine.

Divergent functions of lectin‐like receptors on NK cells

W. Seaman, J. Ryan, 1997, Immunological reviews.

TREM2, a DAP12‐Associated Receptor, Regulates Osteoclast Differentiation and Function

L. Lanier, W. Seaman, M. B. Humphrey, 2005, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

Expression and Activation of Signal Regulatory Protein α on Astrocytomas

E. Huang, W. Seaman, E. Brown, 2004, Cancer Research.

Natural killing of xenogeneic cells mediated by the mouse Ly-49D receptor.

W. Seaman, J. Ryan, G. Butcher, 1999, Journal of immunology.

cDNA cloning of mouse NKR-P1 and genetic linkage with LY-49. Identification of a natural killer cell gene complex on mouse chromosome 6.

W. Seaman, W. Yokoyama, J. Ryan, 1991, Journal of immunology.

Molecular cloning of the NK1.1 antigen, a member of the NKR-P1 family of natural killer cell activation molecules.

W. Seaman, J. Turck, W. Yokoyama, 1992, Journal of immunology.

NKR-P1, an activating molecule on rat natural killer cells, stimulates phosphoinositide turnover and a rise in intracellular calcium.

W. Seaman, J. Ryan, J. Hiserodt, 1991, Journal of immunology.

NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity

W. Seaman, J. Ryan, M. Nakamura, 1995, The Journal of experimental medicine.

Ly-49A, a receptor for H-2Dd, has a functional carbohydrate recognition domain.

W. Seaman, W. Yokoyama, S. Rosen, 1994, Immunity.

Synergistic Ca2+ Responses by Gαi- and Gαq-coupled G-protein-coupled Receptors Require a Single PLCβ Isoform That Is Sensitive to Both Gβγ and Gαq*

M. Simon, I. Fraser, E. Ross, 2010, The Journal of Biological Chemistry.

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLCβ3 to Regulate Intracellular Free Calcium*

M. Simon, D. Decamp, I. Fraser, 2008, Journal of Biological Chemistry.

Monocytosis in the BXSB model for systemic lupus erythematosus

W. Seaman, D. Wofsy, C. Kerger, 1984, The Journal of experimental medicine.

Successful treatment of autoimmunity in NZB/NZW F1 mice with monoclonal antibody to L3T4

W. Seaman, D. Wofsy, 1985, The Journal of experimental medicine.

Faculty Opinions recommendation of A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice.

W. Seaman, 2005 .

Specificity of the Murine NK Cell Inhibitory Restricts the Allelic d Domain of H-2D 2 a The

W. Seaman, J. Ryan, Mary C. Nakamura, 1998 .

The alpha2 domain of H-2Dd restricts the allelic specificity of the murine NK cell inhibitory receptor Ly-49A.

W. Seaman, J. Ryan, K. Kärre, 1998, Journal of immunology.

Depletion of natural killer cells in mice by monoclonal antibody to NK-1.1. Reduction in host defense against malignancy without loss of cellular or humoral immunity.

W. Seaman, G. Koo, E. Eriksson, 1987, Journal of immunology.

Mouse Ly-49D Recognizes H-2Dd and Activates Natural Killer Cell Cytotoxicity

W. Seaman, J. Ortaldo, J. Ryan, 1999, The Journal of experimental medicine.

A family of murine NK cell receptors specific for target cell MHC class I molecules.

D. Margulies, W. Seaman, W. Yokoyama, 1995, Seminars in immunology.

The Innate Immune Response to Salmonella enterica Serovar Typhimurium by Macrophages Is Dependent on TREM2-DAP12

A. Aderem, W. Seaman, Kelly D. Smith, 2008, Infection and Immunity.

Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase

W. Seaman, L. Shultz, J. Ryan, 1997, The Journal of experimental medicine.

Thymic Influences on Autoimmunity in MRL‐1pr Mice

W. Seaman, J. Ledbetter, D. Wofsy, 1982, Scandinavian journal of immunology.

Activating Ly-49 D and Inhibitory Ly-49 A Natural Killer Cell Receptors Demonstrate Distinct Requirements for Interaction with H 2-D d By

W. Seaman, S. Hayashi, J. Ryan, 2000 .

Activating Ly-49d and Inhibitory Ly-49a Natural Killer Cell Receptors Demonstrate Distinct Requirements for Interaction with H2-Dd

W. Seaman, S. Hayashi, J. Ryan, 2000, The Journal of experimental medicine.

Inositol trisphosphate is generated by a rat natural killer cell tumor in response to target cells or to crosslinked monoclonal antibody OX-34: possible signaling role for the OX-34 determinant during activation by target cells.

W. Seaman, J. Imboden, R. Dobrow, 1987, Proceedings of the National Academy of Sciences of the United States of America.

CMRF-35-Like Molecule-1, a Novel Mouse Myeloid Receptor, Can Inhibit Osteoclast Formation1

W. Seaman, D. Ginzinger, M. B. Humphrey, 2003, The Journal of Immunology.

FormationMyeloid Receptor, Can Inhibit Osteoclast CMRF-35-Like Molecule-1, a Novel Mouse

W. Seaman, D. Ginzinger, Nakamura, 2003 .

Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity

W. Seaman, L. Herzenberg, J. Ledbetter, 1981, The Journal of experimental medicine.

The proliferating cells in autoimmune MRL/lpr mice lack L3T4, an antigen on "helper" T cells that is involved in the response to class II major histocompatibility antigens.

R. Hardy, W. Seaman, D. Wofsy, 1984, Journal of immunology.

THE POTENTIAL ROLE OF ARACHIDONIC ACID METABOLISM IN NATURAL KILLER CELL ACTIVITY1

W. Seaman, J. Woodcock, 1985 .

Systemic lupus erythematosus. Contrasts and comparisons.

W. Seaman, A. Steinberg, M. Gershwin, 1975, Annals of internal medicine.

Receptor‐specific Mechanisms for the Responses of Human Leukocytes to Leukotrienes a

W. Seaman, E. Goetzl, L. Baud, 1988, Annals of the New York Academy of Sciences.

Inhibition of humoral immunity in vivo by monoclonal antibody to L3T4: studies with soluble antigens in intact mice.

W. Seaman, D. Wofsy, D. C. Mayes, 1985, Journal of immunology.

Suppression of natural killing in vitro by monocytes and polymorphonuclear leukocytes: requirement for reactive metabolites of oxygen.

Z. Werb, W. Seaman, M. Blackman, 1982, The Journal of clinical investigation.

Effect of estrogen on natural killer cells.

W. Seaman, T. Gindhart, William E. Seaman, 1979, Arthritis and rheumatism.

Natural killing of tumor cells by human peripheral blood cells. Suppression of killing in vitro by tumor-promoting phorbol diesters.

Z. Werb, W. Seaman, M. Blackman, 1981, The Journal of clinical investigation.

TREM )-2 and DAP 12 Receptor Expressed on Myeloid Cells Responses in Macrophages by Triggering Cutting Edge : Inhibition of TLR and FcR

L. Lanier, W. Seaman, J. Hamerman, 2006 .

Ligand interactions by activating and inhibitory Ly‐49 receptors

W. Seaman, Mary C. Nakamura, 2001, Immunological reviews.

Regulation of autoimmunity and donor cell engraftment by recipient Lyt- 2+ cells during the graft-versus-host reaction

W. Seaman, J. Roubinian, S. E. Harper, 1987, The Journal of experimental medicine.

Induction of immune tolerance during administration of monoclonal antibody to L3T4 does not depend on depletion of L3T4+ cells.

W. Seaman, D. Wofsy, N. Carteron, 1988, Journal of immunology.

The Ly-49 and NKR-P1 gene families encoding lectin-like receptors on natural killer cells: the NK gene complex.

W. Seaman, W. Yokoyama, 1993, Annual review of immunology.

Human natural killer cell activity is reversibly inhibited by antagonists of lipoxygenation.

W. Seaman, 1983, Journal of immunology.

Effect of 89Sr on immunity and autoimmunity in NZB/NZW F1 mice.

W. Seaman, M. Blackman, J. Greenspan, 1980, Journal of immunology.

Natural killing in estrogen-treated mice responds poorly to poly I.C despite normal stimulation of circulating interferon.

T. Merigan, W. Seaman, N. Talal, 1979, Journal of immunology.

Natural killer cells, bone, and the bone marrow: studies in estrogen-treated mice and in congenitally osteopetrotic (mi/mi) mice.

W. Seaman, M. Blackman, J. Greenspan, 1979, Journal of immunology.

Harvesting of leukocytes from intestinal lumen in murine giardiasis and preliminary characterization of these cells

W. Seaman, F. Schaefer, R. Owen, 1985, Digestive Diseases and Sciences.

Human and murine natural killer cell activity may require lipoxygenation of arachidonic acid.

W. Seaman, J. Woodcock, 1984, The Journal of allergy and clinical immunology.

The Role of Microglial Subsets in Regulating Brain Injury

W. Seaman, 2009 .

Surface antigens on mouse natural killer cells: use of monoclonal antibodies to inhibit or to enrich cytotoxic activity.

W. Seaman, L. Herzenberg, J. Ledbetter, 1981, Journal of immunology.

Characterization of SIRPs in Prostate Cancer Cells

W. Seaman, 2001 .

Analysis of the function of L3T4+ T cells by in vivo treatment with monoclonal antibody to L3T4

W. Seaman, D. Wofsy, David Wofsy, 1986, Immunologic research.

REGULATION OF THE FUNCTIONS OF LYMPHOID CELLS BY 5-LIPOXYGENASE PRODUCTS OF ARACHIDONIC ACID

W. Seaman, E. Goetzl, L. Baud, 2006 .

LigandsShort-Term Stimulation with 33 Single Expression Changes in Response to Analysis of the Major Patterns of B Cell Gene

R. Scheuermann, Melvin I. Simon, Sangdun Choi, 2004 .

Characterization of TREM‐3, an activating receptor on mouse macrophages: definition of a family of single Ig domain receptors on mouse chromosome 17

W. Seaman, M. Daws, D. Chung, 2002, European journal of immunology.

Induction of immune tolerance by administration of monoclonal antibody to L3T4.

W. Seaman, D. Wofsy, J. H. Scott, 1986, Journal of immunology.

Treatment of autoimmune MRL/Ipr mice with monoclonal antibody to Thy-1.2: a single injection has sustained effects on lymphoproliferation and renal disease.

W. Seaman, J. Ledbetter, D. Wofsy, 1983, Journal of immunology.

Natural killing activity in sjögren's syndrome

V. Strand, W. Seaman, N. Miyasaka, 1983 .

Selective manipulation of the immune response in vivo by monoclonal antibodies.

W. Seaman, D. Wofsy, 1988, Annual review of medicine.

beta-Estradiol reduces natural killer cells in mice.

W. Seaman, M. Blackman, N. Talal, 1978, Journal of immunology.

Avascular necrosis of the talus, scaphoid, and metatarsal head in systemic lupus erythematosus.

W. Seaman, J. Klippel, J. Decker, 1974, Clinical orthopaedics and related research.

Clostridium difficile toxin B differentially affects GPCR‐stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2

D. Decamp, I. Fraser, Keng-mean Lin, 2010, Journal of leukocyte biology.

Aspirin-induced hepatotoxicity in patients with systemic lupus erythematosus.

K. Ishak, W. Seaman, P. Plotz, 1974, Annals of internal medicine.

Cutting Edge: Inhibition of TLR and FcR Responses in Macrophages by Triggering Receptor Expressed on Myeloid Cells (TREM)-2 and DAP121

L. Lanier, W. Seaman, J. Hamerman, 2006, The Journal of Immunology.

Natural killer cells and natural killer T cells.

W. Seaman, William E. Seaman, 2000, Arthritis and rheumatism.

Effect of aspirin on liver tests in patients with RA or SLE and in normal volunteers.

W. Seaman, P. Plotz, P. H. Plotz, 1976, Arthritis and rheumatism.

TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis

F. Brodsky, J. Cyster, W. Seaman, 2005, The Journal of experimental medicine.

Randomized, double-blind, placebo-controlled study of the treatment of the painful shoulder.

M. Petri, W. Seaman, Q. Whiting-O'Keefe, 1987, Arthritis and rheumatism.

Traumatic brain injury induces macrophage subsets in the brain

Charles C. Kim, R. Locksley, W. Seaman, 2013, European journal of immunology.

Factors regulating microglia activation

W. Seaman, C. Cunningham, A. Sierra, 2013 .

Tim‐2 is the receptor for H‐ferritin on oligodendrocytes

B. Todorich, J. Connor, W. Seaman, 2008, Journal of neurochemistry.

A natural killer cell receptor specific for a major histocompatibility complex class I molecule

W. Seaman, W. Yokoyama, B. Daniels, 1994, The Journal of experimental medicine.

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia

W. Seaman, M. Yenari, Christine L. Hsieh, 2009, Journal of Neurochemistry.

β-Estradiol Reduces Natural Killer Cells in Mice

W. Seaman, M. Mandel, 1978, The Journal of Immunology.

Reversal of advanced murine lupus in NZB/NZW F1 mice by treatment with monoclonal antibody to L3T4.

W. Seaman, D. Wofsy, 1987, Journal of immunology.

Pattern Recognition by TREM-2: Binding of Anionic Ligands1

W. Seaman, P. Sullam, N. Tchao, 2003, The Journal of Immunology.

DAP12-mediated Signal Transduction in Natural Killer Cells

W. Seaman, S. Anderson, R. Geahlen, 1998, The Journal of Biological Chemistry.

Analysis of the Major Patterns of B Cell Gene Expression Changes in Response to Short-Term Stimulation with 33 Single Ligands1

Richard H. Scheuermann, Zhen Yan, Shankar Subramaniam, 2004, The Journal of Immunology.

TREM-2 (triggering receptor expressed on myeloid cells 2) is a phagocytic receptor for bacteria

M. Colonna, W. Seaman, S. Branda, 2009, The Journal of cell biology.

Identification and characterization of a cell-surface molecule that is selectively induced on rat lymphokine-activated killer cells.

Craig W. Reynolds, W. Seaman, J. Imboden, 1989, Journal of immunology.

Molecular cloning of gp42, a cell-surface molecule that is selectively induced on rat natural killer cells by interleukin 2: glycolipid membrane anchoring and capacity for transmembrane signaling

W. Seaman, J. Imboden, A. Pollock, 1991, The Journal of experimental medicine.

The OX-44 molecule couples to signaling pathways and is associated with CD2 on rat T lymphocytes and a natural killer cell line

W. Seaman, J. Imboden, E. Niemi, 1992, The Journal of experimental medicine.

Treatment of murine lupus with monoclonal anti-T cell antibody.

W. Seaman, P. Hendler, J. Ledbetter, 1985, Journal of immunology.

Cloning and characterization of a novel mouse myeloid DAP12‐associated receptor family

L. Lanier, W. Seaman, J. Ryan, 2001, European journal of immunology.

The Lyt‐2, Lyt‐3 Macromolecules: Structural and Functional Studies

W. Seaman, J. Ledbetter, 1982, Immunological reviews.

REJECTION OF SKIN GRAFTS AND GENERATION OF CYTOTOXIC T CELLS BY MICE DEPLETED OF L3T4+ CELLS

W. Seaman, D. Wofsy, J. H. Scott, 1986, Transplantation.

The Role of Microglial Subsets in Regulating Traumatic Brain Injury

W. Seaman, 2013 .

Divergent regulation of phospholipase C-alpha and phospholipase C-gamma transcripts during activation of a human T cell line.

W. Seaman, J. Imboden, W. Hempel, 1991, Journal of Immunology.

Expression and activation of signal regulatory protein alpha on astrocytomas.

E. Huang, W. Seaman, E. Brown, 2004, Cancer research.

THE EFFECT OF 17β-ESTRADIOL ON NATURAL KILLING IN THE MOUSE

W. Seaman, N. Talal, 1980 .

Human synovial dendritic cells. Direct observation of transition to fibroblasts.

Z. Werb, W. Seaman, P. Hendler, 1985, The Journal of rheumatology.

Natural killing by spleen cells from W/Wv and Sl/Sld anemic mice.

W. Seaman, N. Talal, 1981, Experimental hematology.

Signaling and Cross-talk by C5a and UDP in Macrophages Selectively Use PLC3 to Regulate Intracellular

M. Simon, D. Decamp, I. Fraser, 2008 .

Suppression or enhancement of natural killing does not alter tolerance to bovine gamma globulin.

W. Seaman, N. Talal, J. Loeb, 1981, Journal of clinical & laboratory immunology.