J. Leroux

发表

Preparation and characterization of pH-responsive polymeric micelles for the delivery of photosensitizing anticancer drugs.

J. Taillefer, M. Jones, N. Brasseur, 2000, Journal of pharmaceutical sciences.

Nanopharmaceuticals: A focus on their clinical translatability.

Jean-Christophe Leroux, J. Leroux, S. Bisso, 2020, International journal of pharmaceutics.

Twin disulfides as opportunity for improving stability and transfection efficiency of oligoaminoethane polyplexes.

J. Leroux, E. Wagner, P. Klein, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Improving oral drug bioavailability with polycations?

J. Leroux, M. Gauthier, Jessica D. Schulz, 2015, European journal of pharmaceutics and biopharmaceutics.

Characterization of Polyion Complex Micelles Designed to Address the Challenges of Oligonucleotide Delivery

J. Leroux, Marie-Hélène Dufresne, Mahmoud Elsabahy, 2008, Pharmaceutical Research.

Polymer based pH-sensitive carriers as a means to improve the cytoplasmic delivery of drugs.

Jean-Christophe Leroux, Françoise M Winnik, J. Leroux, 2002, International journal of pharmaceutics.

Intracellular delivery of colloids: Past and future contributions from microinjection

J. Leroux, Peter Tiefenboeck, Jong Ah Kim, 2018, Advanced drug delivery reviews.

PEG‐coated Poly(lactic acid) Nanoparticles for the Delivery of Hexadecafluoro Zinc Phthalocyanine to EMT‐6 Mouse Mammary Tumours

J. Rousseau, R. Gurny, N. Brasseur, 1995, The Journal of pharmacy and pharmacology.

Photothermal Killing of Cancer Cells by the Controlled Plasmonic Coupling of Silica‐Coated Au/Fe2O3 Nanoaggregates

F. Starsich, G. Sotiriou, S. Pratsinis, 2014 .

Enzyme-Mimetic Antioxidant Luminescent Nanoparticles for Highly Sensitive Hydrogen Peroxide Biosensing.

G. Sotiriou, R. Mezzenga, J. Leroux, 2017, ACS nano.

Novel injectable neutral solutions of chitosan form biodegradable gels in situ.

J. Leroux, M. Buschmann, J. Leroux, 2000, Biomaterials.

Characterization of thermosensitive chitosan gels for the sustained delivery of drugs.

J. Leroux, J. Leroux, A. Chenite, 2000, International journal of pharmaceutics.

Effect of poly(N-vinyl-pyrrolidone)-block-poly(D,L-lactide) as coating agent on the opsonization, phagocytosis, and pharmacokinetics of biodegradable nanoparticles.

Jean-Christophe Leroux, Geneviève Gaucher, J. Leroux, 2009, Biomacromolecules.

Oral delivery of macromolecular drugs: Where we are after almost 100years of attempts.

Jean-Christophe Leroux, Elena Moroz, J. Leroux, 2016, Advanced drug delivery reviews.

pH-Responsive molecular tweezers.

J. Leroux, Hui Gao, J. Leblond, 2010, Journal of the American Chemical Society.

Engineered Polymersomes for the Treatment of Fish Odor Syndrome: A First Randomized Double Blind Olfactory Study

J. Leroux, Yinyin Bao, C. Steuer, 2020, Advanced science.

Biodegradable nanoparticles — From sustained release formulations to improved site specific drug delivery

R. Gurny, J. Leroux, E. Allémann, 1996 .

Microinjection for the ex Vivo Modification of Cells with Artificial Organelles.

J. Leroux, C. Halin, Peter Tiefenboeck, 2017, ACS nano.

Investigating the Mechanism of Cyclodextrins in the Treatment of Niemann-Pick Disease Type C Using Crosslinked 2-Hydroxypropyl-β-cyclodextrin.

R. Mezzenga, B. Werner, J. Leroux, 2020, Small.

In Vitro Extended-Release Properties of Drug-Loaded Poly(DL-Lactic Acid) Nanoparticles Produced by a Salting-Out Procedure

R. Gurny, J. Leroux, E. Allémann, 1993, Pharmaceutical Research.

Formulation and Lyoprotection of Poly(Lactic Acid-Co-Ethylene Oxide) Nanoparticles: Influence on Physical Stability and In Vitro Cell Uptake

J. Feijen, R. Gurny, J. Leroux, 1999, Pharmaceutical Research.

An investigation on the role of plasma and serum opsonins on the internalization of biodegradable poly(D,L-lactic acid) nanoparticles by human monocytes.

R. Gurny, J. Leroux, J. Leroux, 1995, Life sciences.

New approach for the preparation of nanoparticles by an emulsification-diffusion method

R. Gurny, J. Leroux, E. Allémann, 1995 .

Lipids and polymers in pharmaceutical technology: Lifelong companions

M. Alexander, R. Wildman, J. Leroux, 2019, International journal of pharmaceutics.

Polymeric micelles - a new generation of colloidal drug carriers.

M. Jones, J. Leroux, J. Leroux, 1999, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Use of a PEG-conjugated bright near-infrared dye for functional imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis.

Michael Detmar, Jean-Christophe Leroux, Paola Luciani, 2013, Biomaterials.

Breakthrough discoveries in drug delivery technologies: the next 30 years.

J. Leroux, P. Luciani, D. Brambilla, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Conformation–function relationships for the comb-shaped polymer pOEGMA

J. Leroux, M. Gauthier, Mi Liu, 2015 .

Molecular Sieving on the Surface of a Protein Provides Protection Without Loss of Activity

M. Radivojevic, J. Leroux, M. Gauthier, 2013 .

Characterization of Calcium Phosphate Nanoparticles Based on a PEGylated Chelator for Gene Delivery.

J. Leroux, Bastien Castagner, Xiangang Huang, 2017, ACS applied materials & interfaces.

Block copolymer micelles: preparation, characterization and application in drug delivery.

Marie-Hélène Dufresne, Jean-Christophe Leroux, Geneviève Gaucher, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Preparation of polyion complex micelles from poly(ethylene glycol)-block-polyions.

J. Leroux, Marie-Hélène Dufresne, Bastien Castagner, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Reverse micelles from amphiphilic branched polymers

J. Leroux, Marie-Christine G. Jones, 2010 .

Synthesis and Micellar Characterization of Novel Amphiphilic A−B−A Triblock Copolymers of N-(2-Hydroxypropyl)methacrylamide or N-Vinyl-2-pyrrolidone with Poly(ε-caprolactone)

J. Leroux, B. S. Lele, 2002 .

Novel Amphiphilic Diblock Copolymer of Low Molecular Weight Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide): Synthesis, Characterization, and Micellization

J. Leroux, S. Rimmer, S. Gori, 2004 .

Injectable nano-antidotes ( Nanotidotes ) for the treatment of drug overdose and poisoning

J. Leroux, Vincent Forster, 2014 .

The novelty bubble

J. Leroux, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Genetic ablation of SOX18 function suppresses tumor lymphangiogenesis and metastasis of melanoma in mice.

Michael Detmar, Jean-Christophe Leroux, Paola Luciani, 2012, Cancer research.

Twenty-five years of polymersomes: lost in translation?

J. Leroux, Simon Matoori, 2020, Materials Horizons.

Effects of steam sterilization on thermogelling chitosan-based gels.

J. Leroux, M. Buschmann, A. Chenite, 2001, Journal of biomedical materials research.

Three-dimensional Printing of Customized Bioresorbable Airway Stents

J. Leroux, Yinyin Bao, A. Studart, 2020 .

Prolonged circulation and increased tumor accumulation of liposomal vincristine in a mouse model of rhabdomyosarcoma.

J. Leroux, P. Luciani, P. Jaaks, 2017, Nanomedicine.

Liposome‐supported peritoneal dialysis in the treatment of severe hyperammonemia: An investigation on potential interactions

Nicola Zamboni, A. de Gottardi, J. Leroux, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Polymer-coated pH-responsive high-density lipoproteins.

J. Leroux, N. Morone, J. Heuser, 2016, Journal of controlled release : official journal of the Controlled Release Society.

Closed-loop cavitation control for focused ultrasound-mediated blood–brain barrier opening by long-circulating microbubbles

M. Weller, M. Rudin, E. Martin, 2019, Physics in medicine and biology.

Treatments of trimethylaminuria: where we are and where we might be heading.

J. Leroux, Aaron C. Schmidt, 2020, Drug discovery today.

Lipase is essential for the study of in vitro release kinetics from organogels.

J. Leroux, M. Gauthier, Marie-Hélène Dufresne, 2012, Molecular pharmaceutics.

Gene delivery with bisphosphonate-stabilized calcium phosphate nanoparticles.

P. Dittrich, J. Leroux, Elisabeth V Giger, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Coated pelletized dosage form: Effect of compaction on drug release

J. Leroux, S. Bechard, 1992 .

Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo

M. Detmar, J. Leroux, P. Luciani, 2013, Angiogenesis.

Minimally invasive method for the point-of-care quantification of lymphatic vessel function.

Mirko Meboldt, Michael Detmar, Jean-Christophe Leroux, 2019, JCI insight.

Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles.

M. Detmar, J. Leroux, Athanasia Dasargyri, 2016, Journal of controlled release : official journal of the Controlled Release Society.

On the characterization of pH-sensitive liposome/polymer complexes.

M. Lafleur, J. Leroux, E. Roux, 2003, Biomacromolecules.

In vivo evaluation of pH-sensitive polymer-based immunoliposomes targeting the CD33 antigen.

J. Leroux, P. Simard, 2010, Molecular pharmaceutics.

Ratiometric Fluorescent Probes for the Detection of Reactive Oxygen Species.

J. Leroux, P. Luciani, D. Andina, 2017, Chemistry.

Internalization of poly(D,L-lactic acid) nanoparticles by isolated human leukocytes and analysis of plasma proteins adsorbed onto the particles.

L. Balant, R. Gurny, J. Leroux, 1994, Journal of biomedical materials research.

Quantitative analysis of the deposited nanoparticle dose on cell cultures by optical absorption spectroscopy.

G. Sotiriou, J. Leroux, A. Spyrogianni, 2016, Nanomedicine.

Peritoneal dialysis beyond kidney failure?

J. Leroux, O. Devuyst, Anna Pratsinis, 2018, Journal of controlled release : official journal of the Controlled Release Society.

Challenges and Opportunities in 3D Printing of Biodegradable Medical Devices by Emerging Photopolymerization Techniques

J. Leroux, Yinyin Bao, N. Paunović, 2022, Advanced Functional Materials.

Opposing roles of endothelial and leukocyte-expressed IL-7Rα in the regulation of psoriasis-like skin inflammation

J. Leroux, C. Halin, Anna K. Polomska, 2019, Scientific Reports.

An Investigation of PS-b-PEO Polymersomes for the Oral Treatment and Diagnosis of Hyperammonemia.

C. Rose, Eric J. Fischer, J. Leroux, 2019, Small.

Treatment of calcium channel blocker-induced cardiovascular toxicity with drug scavenging liposomes.

J. Leroux, P. Luciani, Vincent Forster, 2012, Biomaterials.

Broad control of disulfide stability through microenvironmental effects and analysis in complex redox environments.

J. Leroux, M. Gauthier, Lorine Brülisauer, 2013, Biomacromolecules.

Tracking the bioreduction of disulfide-containing cationic dendrimers.

J. Leroux, M. Gauthier, Lorine Brülisauer, 2012, Angewandte Chemie.

Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers

R. Maj, M. Burnier, D. Newby, 2020, Nature Communications.

Aminated linear and star-shape poly(glycerol methacrylate)s: synthesis and self-assembling properties.

J. Leroux, Hui Gao, Mahmoud Elsabahy, 2010, Biomacromolecules.

A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study

J. Leroux, I. Pereira de Sousa, Charlotte Gourmel, 2019, Scientific Reports.

Dynamics of lymphatic regeneration and flow patterns after lymph node dissection

M. Detmar, J. Leroux, P. Luciani, 2013, Breast Cancer Research and Treatment.

Modular design of redox-responsive stabilizers for nanocrystals.

J. Leroux, M. Gauthier, Anna K. Polomska, 2013, ACS nano.

Crosslinkable polymers for nanocrystal stabilization.

J. Leroux, M. Gauthier, Kathrin Fuhrmann, 2010, Journal of controlled release : official journal of the Controlled Release Society.

Activity-Based Approach for Selective Molecular CO2 Sensing.

J. Leroux, Ori Green, B. Morandi, 2022, Journal of the American Chemical Society.

Bio-reduction of redox-sensitive albumin conjugates in FcRn-expressing cells.

J. Leroux, M. Gauthier, Gina Valentino, 2014, Angewandte Chemie.

Kinetics of blood component adsorption on poly(D,L-lactic acid) nanoparticles: evidence of complement C3 component involvement.

L. Balant, R. Gurny, J. Leroux, 1997, Journal of biomedical materials research.

Gastroresistant oral peptide for fluorescence imaging of colonic inflammation.

G. Rogler, J. Leroux, P. Luciani, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology

U. Kutay, J. Leroux, Peter Tiefenboeck, 2017, eLife.

Preparation of PEGylated liposomes incorporating lipophilic lomeguatrib derivatives for the sensitization of chemo-resistant gliomas.

M. Weller, E. Martin, B. Werner, 2018, International journal of pharmaceutics.

Is 3D Printing of Pharmaceuticals a Disruptor or Enabler?

J. Leroux, D. Brambilla, Kun Liang, 2018, Advanced materials.

Poly(ethylene glycol)-alendronate coated nanoparticles for magnetic resonance imaging of lymph nodes

J. Leroux, S. Bisso, D. Brambilla, 2018, Journal of drug targeting.

Site‐Specific Polymer Conjugation Stabilizes Therapeutic Enzymes in the Gastrointestinal Tract

D. Hilvert, J. Leroux, M. Gauthier, 2016, Advanced materials.

Tumor and Stem Cell Biology Genetic Ablation of SOX 18 Function Suppresses Tumor Lymphangiogenesis and Metastasis of Melanoma in Mice

M. Detmar, J. Leroux, P. Luciani, 2012 .

Toxicity of silver nanoparticles in macrophages.

G. Sotiriou, S. Pratsinis, J. Leroux, 2013, Small.

Recent advances in the treatment of hyperammonemia.

J. Leroux, Simon Matoori, 2015, Advanced drug delivery reviews.

Permeation of steryl ferulates through an in vitro intestinal barrier model.

J. Leroux, Dan Zhu, L. Nyström, 2015, Molecular nutrition & food research.

Pharmacokinetics of a novel HIV-1 protease inhibitor incorporated into biodegradable or enteric nanoparticles following intravenous and oral administration to mice.

R. Gurny, R. Cozens, J. Leroux, 1995, Journal of pharmaceutical sciences.

Releasable and traceless PEGylation of arginine-rich antimicrobial peptides† †Electronic supplementary information (ESI) available: Experimental procedures, synthesis and characterization of rPEGylation reagents and peptide–PEG conjugates, kinetic studies of PEGylation and dePEGylation (HPLC) and co

J. Leroux, M. Gauthier, Y. Gong, 2017, Chemical science.

Association of cyclosporin to isohexylcyanoacrylate nanospheres and subsequent release in human plasma in vitro.

V. Lenaerts, J. Leroux, F. Chouinard, 1992, Journal of microencapsulation.

Investigational therapies for primary hyperoxaluria.

J. Leroux, Anna Kletzmayr, M. Ivarsson, 2020, Bioconjugate chemistry.

Activatable cell penetrating peptide-peptide nucleic acid conjugate via reduction of azobenzene PEG chains.

J. Leroux, Soo Hyeon Lee, Elena V. Moroz, 2014, Journal of the American Chemical Society.

Proton-actuated membrane-destabilizing polyion complex micelles.

J. Leroux, Marie-Hélène Dufresne, M. Yessine, 2007, Bioconjugate chemistry.

Light‐Based Printing of Leachable Salt Molds for Facile Shaping of Complex Structures

S. Ferguson, J. Leroux, Yinyin Bao, 2022, Advanced materials.

Optimization of an ammonia assay based on transmembrane pH-gradient polymersomes

J. Leroux, A. Spyrogianni, Charlotte Gourmel, 2021, Scientific Reports.

Preclinical evaluation of liposome-supported peritoneal dialysis for the treatment of hyperammonemic crises.

J. Leroux, B. Thöny, J. Häberle, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival

J. Leroux, P. Luciani, R. Rieben, 2019, Scientific Reports.

Well-Defined Multivalent Ligands for Hepatocytes Targeting via Asialoglycoprotein Receptor.

J. Leroux, Bastien Castagner, Xiangang Huang, 2017, Bioconjugate chemistry.

The interactions of amphiphilic antisense oligonucleotides with serum proteins and their effects on in vitro silencing activity.

J. Leroux, G. Deleavey, M. Damha, 2012, Biomaterials.

Drug-scavenging Liposomes Attenuate the Cardiovascular Toxicity of Overdosed Calcium Channel Blockers

J. Leroux, P. Luciani, Vincent Forster, 2012 .

Core Cross-Linked Reverse Micelles from Star-Shaped Polymers

J. Leroux, Hui Gao, R. Prud’homme, 2008 .

Digital Light 3D Printed Bioresorbable and NIR‐Responsive Devices with Photothermal and Shape‐Memory Functions

J. Leroux, Yinyin Bao, A. Studart, 2022, Advanced science.

Ammonia uptake by transmembrane pH gradient poly(isoprene)-block-poly(ethylene glycol) polymersomes.

K. Altmann, J. Leroux, Yinyin Bao, 2020, Soft matter.

Tuning Multicolor Emission from a Single Fluorophore via Controlled Radical Polymerization-Mediated Charge Transfer

J. Leroux, C. Shih, Yinyin Bao, 2020 .

3D printing of a controlled fluoride delivery device for the prevention and treatment of tooth decay.

J. Leroux, Zhi Luo, V. Berger, 2022, Journal of controlled release : official journal of the Controlled Release Society.

Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles.

J. Leroux, Mahmoud Elsabahy, N. Bertrand, 2007, Biomacromolecules.

Ultra-Sub-Stoichiometric 'Dynamic' Bioconjugation Reduces Viscosity by Disrupting Immunoglobulin Oligomerization.

J. Leroux, M. Kuentz, Andreas Niederquell, 2019, Biomacromolecules.

A Chiral Phosphoramidite Reagent for the Synthesis of Inositol Phosphates.

J. Leroux, Bastien Castagner, Estelle Durantie, 2016, Organic letters.

Investigational Pharmacological Treatments for Vascular Calcification

J. Leroux, Antonia E. Schantl, M. Ivarsson, 2018, Advanced Therapeutics.

Star‐shaped alkylated poly(glycerol methacrylate) reverse micelles: Synthesis and evaluation of their solubilizing properties in dichloromethane

J. Leroux, Hui Gao, Marie-Christine G. Jones, 2007 .

Inhibition of vascular calcification by inositol phosphates derivatized with ethylene glycol oligomers

R. Maj, M. Burnier, D. Newby, 2020, Nature Communications.

Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates.

J. Leroux, P. Luciani, P. Walde, 2013, Nature chemistry.

Elucidating the mechanism of cyclodextrins in the treatment of Niemann-Pick Disease Type C using crosslinked 2-hydroxypropyl-β-cyclodextrin

R. Mezzenga, B. Werner, J. Leroux, 2020, bioRxiv.

Characterization of the membrane-destabilizing properties of different pH-sensitive methacrylic acid copolymers.

M. Lafleur, J. Leroux, M. Yessine, 2003, Biochimica et biophysica acta.

In vitro characterization of a novel polymeric-based pH-sensitive liposome system.

J. Leroux, M. Zignani, D. Drummond, 2000, Biochimica et biophysica acta.

Corrigendum: Sustained gastrointestinal activity of dendronized polymer-enzyme conjugates.

J. Leroux, P. Luciani, P. Walde, 2016, Nature chemistry.

Stereocomplex block copolymer micelles: core-shell nanostructures with enhanced stability.

Jean-Christophe Leroux, Geneviève Gaucher, J. Leroux, 2005, Nano letters.

Interplay of chemical microenvironment and redox environment on thiol-disulfide exchange kinetics.

J. Leroux, M. Gauthier, Chuanliu Wu, 2011, Chemistry.

Machine learning-assisted exploration of a versatile polymer platform with charge transfer-dependent full-color emission

D. Winkler, J. Leroux, S. Russo, 2023, Chem.

Biomedical applications of bisphosphonates.

Jean-Christophe Leroux, J. Leroux, Elisabeth V Giger, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Inhibitors of Calcium Oxalate Crystallization for the Treatment of Oxalate Nephropathies

H. Anders, J. Leroux, S. R. Mulay, 2020, Advanced science.

Thermosensitive chitosan-based hydrogel containing liposomes for the delivery of hydrophilic molecules.

J. Leroux, J. Leroux, P. Hildgen, 2002, Journal of controlled release : official journal of the Controlled Release Society.

Microneedles for the Noninvasive Structural and Functional Assessment of Dermal Lymphatic Vessels.

Michael Detmar, Jean-Christophe Leroux, Davide Brambilla, 2016, Small.

3D printing of a wearable personalized oral delivery device: A first-in-human study

Davide Brambilla, Jean-Christophe Leroux, Kun Liang, 2018, Science Advances.

Improving the Stability and Activity of Oral Therapeutic Enzymes—Recent Advances and Perspectives

J. Leroux, G. Fuhrmann, 2014, Pharmaceutical Research.

Preparation and characterization of water-soluble pH-sensitive nanocarriers for drug delivery.

J. Leroux, Marie-Hélène Dufresne, V. Sant, 2004, International journal of pharmaceutics.

Semi-permeable coatings fabricated from comb-polymers efficiently protect proteins in vivo

Jean-Christophe Leroux, J. Leroux, M. Gauthier, 2014, Nature Communications.

Pharmacokinetics of lipid‐drug conjugates loaded into liposomes

J. Leroux, P. Luciani, D. Brambilla, 2018, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Structural properties and gene-silencing activity of chemically modified DNA–RNA hybrids with parallel orientation

Jonathan Hall, J. Leroux, M. Damha, 2018, Nucleic acids research.

Solubilization of cyclosporin A in dextran-g-polyethyleneglycolalkyl ether polymeric micelles.

J. Leroux, M. Francis, F. Winnik, 2003, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Strategies to design push-pull osmotic systems for delivering low and pH-dependent soluble drugs

R. Gurny, J. Leroux, Docteur N. Loggia, 2018 .

Releasable Conjugation of Polymers to Proteins.

J. Leroux, M. Gauthier, Y. Gong, 2015, Bioconjugate chemistry.

New pharmaceutical applications for macromolecular binders.

J. Leroux, M. Gauthier, J. Leblond, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Improving the Stability and Activity of Oral Therapeutic Enzymes—Recent Advances and Perspectives

Jean-Christophe Leroux, Gregor Fuhrmann, J. Leroux, 2013, Pharmaceutical Research.

Chemotherapy sensitization of glioblastoma by focused ultrasound‐mediated delivery of therapeutic liposomes

M. Weller, M. Rudin, E. Martin, 2019, Journal of controlled release : official journal of the Controlled Release Society.

Self-assembled nanocages for hydrophilic guest molecules.

J. Leroux, D. Pochan, Kelly Hales, 2006, Journal of the American Chemical Society.

Is there a future for cell-penetrating peptides in oligonucleotide delivery?

J. Leroux, Soo Hyeon Lee, Bastien Castagner, 2013, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

PEG nanocages as non-sheddable stabilizers for drug nanocrystals.

J. Leroux, M. Gauthier, Jessica D. Schulz, 2012, ACS nano.

Rapid Characterization and Quantification of Extracellular Vesicles by Fluorescence‐Based Microfluidic Diffusion Sizing

J. Leroux, P. Arosio, G. Adamo, 2021, Advanced healthcare materials.

Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling

M. Detmar, J. Leroux, E. Stanley, 2016, Angiogenesis.

Preparation of PEGylated chelator-stabilized calcium phosphate nanoparticles for liver-targeted delivery of nucleic acid.

J. Leroux, Bastien Castagner, Xiangang Huang, 2015, Journal of controlled release : official journal of the Controlled Release Society.

siRNA Transfection with Calcium Phosphate Nanoparticles Stabilized with PEGylated Chelators

J. Leroux, J. Mönkkönen, J. Räikkönen, 2013, Advanced healthcare materials.

Encapsulation of Hydrophilic Compounds in Small Extracellular Vesicles: Loading Capacity and Impact on Vesicle Functions

J. Leroux, B. Hettich, Johannes Bader, 2021, Advanced healthcare materials.

Exosomes for Wound Healing: Purification Optimization and Identification of Bioactive Components

S. Werner, J. Leroux, Maya Ben-Yehuda Greenwald, 2020, Advanced science.

siRNA nanocarriers based on methacrylic acid copolymers.

J. Leroux, Mahmoud Elsabahy, G. Deleavey, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Development of a Kidney Calcification Inhibitor Employing Image-Based Profiling: A Proof-of-Concept Study.

J. Leroux, M. Kuro-o, E. Montanari, 2020, ACS pharmacology & translational science.

Valerio Zolla, Arturo Casadevall, Jean-Christophe Leroux, 2015, Aging cell.

Plasmonic biocompatible silver-gold alloyed nanoparticles.

Sotiris E. Pratsinis, Georgios A. Sotiriou, Jean-Christophe Leroux, 2014, Chemical communications.

In vivo visualization and quantification of collecting lymphatic vessel contractility using near-infrared imaging

F. Scholkmann, M. Detmar, J. Leroux, 2016, Scientific Reports.

pH-sensitive vesicles, polymeric micelles, and nanospheres prepared with polycarboxylates.

J. Leroux, Marie-Hélène Dufresne, Arnaud E Felber, 2012, Advanced drug delivery reviews.

Nano-antidotes for drug overdose and poisoning

J. Leroux, Vincent Forster, 2015, Science Translational Medicine.

Liposome‐Supported Peritoneal Dialysis for the Treatment of Hyperammonemia‐Associated Encephalopathy

C. Rose, J. Leroux, M. Tremblay, 2016 .

Transmembrane pH-gradient liposomes to treat cardiovascular drug intoxication.

J. Leroux, N. Bertrand, P. Moreau, 2010, ACS nano.

Targeting bacterial toxins.

J. Leroux, Bastien Castagner, M. Ivarsson, 2012, Angewandte Chemie.

Liposome-supported peritoneal dialysis for detoxification of drugs and endogenous metabolites

J. Leroux, M. Roveri, Vincent Forster, 2014, Science Translational Medicine.

Investigational new treatments for Clostridium difficile infection.

J. Leroux, Bastien Castagner, M. Ivarsson, 2015, Drug discovery today.

Prevention of the sticking tendency of floating minitablets filled into hard gelatin capsules

J. Leroux, E. Doelker, P. Buri, 1997 .

Enzymatic degradation of cross-linked high amylose starch tablets and its effect on in vitro release of sodium diclofenac.

F. Nekka, V. Lenaerts, J. Leroux, 2001, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Development and physico-chemical characterization of a liposomal formulation of istaroxime.

Jean-Christophe Leroux, Paola Luciani, J. Leroux, 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Celiac Disease: A Challenging Disease for Pharmaceutical Scientists

J. Leroux, Simon Matoori, G. Fuhrmann, 2012, Pharmaceutical Research.

Targeting Nanocarriers with Anisamide: Fact or Artifact?

J. Leroux, Athanasia Dasargyri, Carole D. Kümin, 2017, Advanced materials.

Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling

M. Detmar, J. Leroux, E. Stanley, 2016, Angiogenesis.

Quantitative imaging of lymphatic function with liposomal indocyanine green.

Michael Detmar, Jean-Christophe Leroux, Paola Luciani, 2010, Cancer research.

Decline of lymphatic vessel density and function in murine skin during aging

Michael Detmar, Jean-Christophe Leroux, Paola Luciani, 2015, Angiogenesis.

Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles

P. Couvreur, J. Leroux, S. Bisso, 2019, bioRxiv.

Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery.

M. Detmar, J. Leroux, P. Luciani, 2013, Journal of controlled release : official journal of the Controlled Release Society.

Peptides for tumor-specific drug targeting: state of the art and beyond.

J. Leroux, P. Luciani, M. Bernasconi, 2017, Journal of materials chemistry. B.

Physical methods for enhancing drug absorption from the gastrointestinal tract.

J. Leroux, N. Paunović, Zhi Luo, 2021, Advanced drug delivery reviews.

The TFAMoplex—Conversion of the Mitochondrial Transcription Factor A into a DNA Transfection Agent

J. Leroux, Michael Burger, Seraina Kaelin, 2022, Advanced science.

DNA unchained: two assays to discover and study inhibitors of the DNA clustering function of barrier-to-autointegration factor

J. Leroux, Caroline Schmitt-Koopmann, Michael Burger, 2020, Scientific Reports.

In‐vitro and in‐vivo evaluation of pH‐responsive polymeric micelles in a photodynamic cancer therapy model

V. Lenaerts, J. Taillefer, N. Brasseur, 2001, The Journal of pharmacy and pharmacology.

Current and forthcoming approaches for systemic detoxification.

Liangfang Zhang, J. Leroux, 2015, Advanced drug delivery reviews.

In vitro evaluation of pH-sensitive polymer/niosome complexes.

J. Leroux, M. Francis, F. Winnik, 2001, Biomacromolecules.

Amphiphilic Cyclodextrin‐Based Nanoparticulate Vaccines Can Trigger T‐Cell Immune Responses

J. Leroux, B. Gander, C. Halin, 2021, Advanced NanoBiomed Research.

Microfluidic Shrinking Droplet Concentrator for Analyte Detection and Phase Separation of Protein Solutions.

J. Leroux, P. Arosio, S. Stavrakis, 2020, Analytical chemistry.

Self assembling properties of aminated poly(glycerol methacrylate)s.

J. Leroux, Hui Gao, Mahmoud Elsabahy, 2011, Journal of controlled release : official journal of the Controlled Release Society.

Dual delivery of nucleic acids and PEGylated-bisphosphonates via calcium phosphate nanoparticles

P. Couvreur, J. Leroux, S. Bisso, 2019, bioRxiv.

Disulfide-containing parenteral delivery systems and their redox-biological fate.

Jean-Christophe Leroux, J. Leroux, M. Gauthier, 2014, Journal of controlled release : official journal of the Controlled Release Society.

Delivery of Hydrophobic Drugs through Self-Assembling Nanostructures

Jean-Christophe Leroux, Geneviève Gaucher, Elvire Fournier, 2004, 2004 International Conference on MEMS, NANO and Smart Systems (ICMENS'04).

Targeting of injectable drug nanocrystals.

J. Leroux, M. Gauthier, Kathrin Fuhrmann, 2014, Molecular pharmaceutics.

In Vitro and In Vivo Evaluation of PEGylated Layer-by-Layer Polyelectrolyte-Coated Paclitaxel Nanocrystals.

J. Leroux, M. Gauthier, Anna K. Polomska, 2017, Small.

Editorial: Drug Delivery: Too Much Complexity, Not Enough Reproducibility?

Jean-Christophe Leroux, J. Leroux, 2017, Angewandte Chemie.

Digital light 3D printing of customized bioresorbable airway stents with elastomeric properties

J. Leroux, Yinyin Bao, A. Studart, 2021, Science Advances.

Serum-stable, long-circulating, pH-sensitive PEGylated liposomes.

J. Leroux, N. Bertrand, P. Simard, 2010, Methods in molecular biology.

N-methyl pyrrolidone/bone morphogenetic protein-2 double delivery with in situ forming implants.

J. Leroux, F. Weber, Lindsay S. Karfeld-Sulzer, 2015, Journal of controlled release : official journal of the Controlled Release Society.

Quantitative measurement of lymphatic function in mice by noninvasive near-infrared imaging of a peripheral vein.

Michael Detmar, Jean-Christophe Leroux, M. Detmar, 2017, JCI insight.

Twin disulfides for orthogonal disulfide pairing and the directed folding of multicyclic peptides.

J. Leroux, M. Gauthier, Chuanliu Wu, 2012, Nature chemistry.

Decline of lymphatic vessel density and function in murine skin during aging

M. Detmar, J. Leroux, P. Luciani, 2015, Angiogenesis.

Amphipathic homopolymers for siRNA delivery: probing impact of bifunctional polymer composition on transfection.

J. Leroux, M. Stuparu, Anzar Khan, 2014, Biomacromolecules.

Poly(N-vinylpyrrolidone)-block-poly(D,L-lactide) as a new polymeric solubilizer for hydrophobic anticancer drugs: in vitro and in vivo evaluation.

J. Leroux, M. Yessine, J. Leroux, 2004, Journal of controlled release : official journal of the Controlled Release Society.

An investigation of PS-b-PEO polymersomes for the oral treatment and diagnosis of hyperammonemia

C. Rose, Eric J. Fischer, J. Leroux, 2019, bioRxiv.

Study of molecular interactions between a phospholipidic layer and a pH-sensitive polymer using the Langmuir balance technique.

J. Leroux, E. Roux, S. Giasson, 2004, Langmuir : the ACS journal of surfaces and colloids.

Layer-by-Layer Coating of Solid Drug Cores: A Versatile Method to Improve Stability, Control Release and Tune Surface Properties.

J. Leroux, Anna K. Polomska, D. Brambilla, 2017, Macromolecular bioscience.

Thiol-Functionalized Poly(ethylene glycol)-b-polyesters: Synthesis and Characterization

J. Leroux, S. Rimmer, P. Sarker, 2007 .

Presumed LRP1-targeting transport peptide delivers β-secretase inhibitor to neurons in vitro with limited efficiency

J. Leroux, Jong Ah Kim, T. Casalini, 2016, Scientific Reports.

Delivery of Nucleic Acids through the Controlled Disassembly of Multifunctional Nanocomplexes

J. Leroux, Mahmoud Elsabahy, G. Deleavey, 2009 .

Non-invasive dynamic near-infrared imaging and quantification of vascular leakage in vivo

M. Detmar, J. Leroux, P. Luciani, 2013, Angiogenesis.

Small-Molecule Allosteric Triggers of Clostridium difficile Toxin B Auto-proteolysis as a Therapeutic Strategy.

J. Leroux, Wangxue Chen, Jun Lu, 2019, Cell chemical biology.

Chronic High-Fat Diet Impairs Collecting Lymphatic Vessel Function in Mice

M. Detmar, J. Leroux, P. Luciani, 2014, PloS one.

Steric stabilization of liposomes by pH-responsive N-isopropylacrylamide copolymer.

J. Leroux, E. Roux, M. Pézolet, 2002, Journal of pharmaceutical sciences.

Delivery of Rapamycin Using In Situ Forming Implants Promotes Immunoregulation and Vascularized Composite Allograft Survival

J. Leroux, P. Luciani, R. Rieben, 2019, Scientific Reports.

An oral redox-sensitive self-immolating prodrug strategy.

J. Leroux, Bastien Castagner, Andrea Morger, 2015, Chemical communications.

Block copolymer micelles: Engineering versatile carriers for drugs and biomacromolecules

Jean-Christophe Leroux, J. Leroux, 2003 .

Solvent-Free Three-Dimensional Printing of Biodegradable Elastomers Using Liquid Macrophotoinitiators

J. Leroux, Yinyin Bao, A. Studart, 2021, Macromolecules.

Carrier-free Gene Silencing by Amphiphilic Nucleic Acid Conjugates in Differentiated Intestinal Cells

Jonathan Hall, J. Leroux, Soo Hyeon Lee, 2016, Molecular therapy. Nucleic acids.

Near‐UV activated, photostable nanophosphors for in vitro dosimetry and dynamic bioimaging

F. Starsich, G. Sotiriou, J. Leroux, 2018 .

Thiol-functionalized polymeric micelles: from molecular recognition to improved mucoadhesion.

Marie-Hélène Dufresne, Jean-Christophe Leroux, J. Leroux, 2005, Bioconjugate chemistry.

Tough PEG‐only hydrogels with complex 3D structure enabled by digital light processing of “all‐PEG” resins

J. Leroux, Adva Krivitsky, Yinyin Bao, 2023, Aggregate.

Liposome-supported enzymatic peritoneal dialysis.

Eric J. Fischer, J. Leroux, P. Luciani, 2017, Biomaterials.

Continuous color tuning of single-fluorophore emission via polymerization-mediated through-space charge transfer

J. Leroux, C. Shih, S. Ye, 2021, Science Advances.

Get out or die trying: peptide- and protein-based endosomal escape of RNA therapeutics.

J. Leroux, Michael Burger, A. Klipp, 2023, Advanced drug delivery reviews.

3D Printing of Recyclable Elastomers with Controllable Degradation and Adhesive Properties

J. Leroux, S. Bisso, C. Weber, 2021 .

Preparation and tumor cell uptake of poly(N-isopropylacrylamide) folate conjugates.

J. Leroux, M. Francis, F. Winnik, 2002, Bioconjugate chemistry.

The use of drug-loaded nanoparticles in cancer chemotherapy

R. Gurny, J. Leroux, E. Doelker, 1996 .

Development of a Modular Ratiometric Fluorescent Probe for the Detection of Extracellular Superoxide.

J. Leroux, P. Luciani, D. Brambilla, 2017, Chemistry.

Lipids and polymers in pharmaceutical technology: Lifelong companions

R. Wildman, J. Leroux, C. Roberts, 2019, International journal of pharmaceutics.

Findings questioning the involvement of Sigma-1 receptor in the uptake of anisamide-decorated particles.

M. Detmar, J. Leroux, Athanasia Dasargyri, 2016, Journal of controlled release : official journal of the Controlled Release Society.

pH-Sensitive Nanoparticles: An Effective Means to Improve the Oral Delivery of HIV-1 Protease Inhibitors in Dogs

R. Gurny, R. Cozens, J. Leroux, 1996, Pharmaceutical Research.

4D printing of biodegradable elastomers with tailorable thermal response at physiological temperature.

J. Leroux, A. Studart, A. Krivitsky, 2023, Journal of controlled release : official journal of the Controlled Release Society.

Drug permeation through a swollen cross-linked amylose starch membrane

V. Lenaerts, J. Leroux, M. Rahmouni, 2003 .

Blood-brain barrier opening-based local delivery of 80 nm-sized liposomes in mice using pulsed focused ultrasound

E. Martin, B. Werner, J. Leroux, 2015, Journal of Therapeutic Ultrasound.

Characterization of Calcium Phosphate Nanoparticles Based on a PEGylated Chelator for Gene Delivery.

J. Leroux, Bastien Castagner, Xiangang Huang, 2017, ACS applied materials & interfaces.