S. Spinelli

发表

Conformations of immunoglobulin hypervariable regions

A. Lesk, C. Chothia, M. Levitt, 1989, Nature.

Exploiting Antigenic Diversity for Vaccine Design

Xavier Daura, Guido Scarabelli, Martin Zacharias, 2010, The Journal of Biological Chemistry.

Three camelid VHH domains in complex with porcine pancreatic alpha-amylase. Inhibition and versatility of binding topology.

L. Wyns, A. Desmyter, S. Muyldermans, 2002, The Journal of biological chemistry.

Three Camelid VHH Domains in Complex with Porcine Pancreatic α-Amylase

Lode Wyns, Serge Muyldermans, Christian Cambillau, 2002, The Journal of Biological Chemistry.

Crystal Structure of ORF12 from Lactococcus lactis Phage p2 Identifies a Tape Measure Protein Chaperone

Sylvain Moineau, Christian Cambillau, G. Sciara, 2008, Journal of bacteriology.

Receptor-Binding Protein of Lactococcus lactis Phages: Identification and Characterization of the Saccharide Receptor-Binding Site

A. Desmyter, C. Cambillau, S. Spinelli, 2006, Journal of bacteriology.

Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses

Sylvain Moineau, Christian Cambillau, A. Desmyter, 2006, Nature Structural &Molecular Biology.

Type VI secretion TssK baseplate protein exhibits structural similarity with phage receptor-binding proteins and evolved to bind the membrane complex

A. Desmyter, C. Cambillau, S. Spinelli, 2017, Nature Microbiology.

Isolation of Llama Antibody Fragments for Prevention of Dandruff by Phage Display in Shampoo

G. Vriend, C. Cambillau, S. Spinelli, 2005, Applied and Environmental Microbiology.

Camelid VHH Domains in Complex with Porcine Pancreatic alpha-Amylase

L. Wyns, A. Desmyter, S. Muyldermans, 2002 .

Domain swapping of a llama VHH domain builds a crystal‐wide β‐sheet structure

Mariella Tegoni, Christian Cambillau, A. Desmyter, 2004 .

Directed in Vitro Evolution and Crystallographic Analysis of a Peptide-binding Single Chain Antibody Fragment (scFv) with Low Picomolar Affinity*

A. Plückthun, C. Cambillau, S. Spinelli, 2004, Journal of Biological Chemistry.

Biochemical and structural characterization of non‐glycosylated Yarrowia lipolytica LIP2 lipase

C. Cambillau, S. Spinelli, F. Carrière, 2013 .

Evolved distal tail carbohydrate binding modules of Lactobacillus phage J‐1: a novel type of anti‐receptor widespread among lactic acid bacteria phages

C. Cambillau, S. Spinelli, M. Dieterle, 2017, Molecular microbiology.

The Atomic Structure of the Phage Tuc2009 Baseplate Tripod Suggests that Host Recognition Involves Two Different Carbohydrate Binding Modules

A. Desmyter, N. Richet, C. Cambillau, 2016, mBio.

Structure of the host-recognition device of Staphylococcus aureus phage ϕ11

C. Cambillau, S. Spinelli, T. Stehle, 2016, Scientific Reports.

Crystal Structure and Self-Interaction of the Type VI Secretion Tail-Tube Protein from Enteroaggregative Escherichia coli

C. Cambillau, S. Spinelli, A. Roussel, 2014, PloS one.

Structural Characterization and Oligomerization of the TssL Protein, a Component Shared by Bacterial Type VI and Type IVb Secretion Systems*

C. Cambillau, S. Spinelli, L. Journet, 2012, The Journal of Biological Chemistry.

Structural Characterization and Oligomerization of the TssL Protein, a Component Shared by Bacterial Type VI and Type

C. Cambillau, S. Spinelli, L. Journet, 2012 .

Structure-Function Analysis of the C-Terminal Domain of the Type VI Secretion TssB Tail Sheath Subunit.

C. Cambillau, S. Spinelli, E. Cascales, 2017, Journal of molecular biology.

Crystal structure of Apis mellifera OBP14, a C-minus odorant-binding protein, and its complexes with odorant molecules.

C. Cambillau, S. Spinelli, P. Pelosi, 2012, Insect biochemistry and molecular biology.

Crystal structure of a novel type of odorant-binding protein from Anopheles gambiae, belonging to the C-plus class.

C. Cambillau, S. Spinelli, P. Pelosi, 2011, The Biochemical journal.

Optimization of crystals from nanodrops: crystallization and preliminary crystallographic study of a pheromone-binding protein from the honeybee Apis mellifera L.

C. Cambillau, S. Spinelli, A. Gruez, 2003, Acta crystallographica. Section D, Biological crystallography.

Crystal Structure of the VgrG1 Actin Cross-linking Domain of the Vibrio cholerae Type VI Secretion System

D. Raoult, C. Cambillau, S. Spinelli, 2012, The Journal of Biological Chemistry.

Biogenesis and structure of a type VI secretion membrane core complex

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Nature.

Quaternary structure of alpha‐crustacyanin from lobster as seen by small‐angle X‐ray scattering

C. Cambillau, S. Spinelli, P. F. Zagalsky, 2003, FEBS Letters.

Priming and polymerization of a bacterial contractile tail structure

C. Cambillau, S. Spinelli, R. Fronzes, 2016, Nature.

Laminin (cid:1) 2 Chain-Positive Vessels and Epidermal Growth Factor in Lung Neuroendocrine Carcinoma A Model of a Novel Cooperative Role of Laminin-2 and Epidermal Growth Factor in Vessel Neoplastic Invasion and Metastasis

G. F. Coloni, S. Spinelli, P. Natali, 2022 .

Structure and specificity of the Type VI secretion system ClpV-TssC interaction in enteroaggregative Escherichia coli

C. Cambillau, S. Spinelli, L. Journet, 2016, Scientific Reports.

Structural Mimicry of Receptor Interaction by Antagonistic Interleukin-6 (IL-6) Antibodies*

A. Desmyter, C. Cambillau, S. Spinelli, 2016, The Journal of Biological Chemistry.

The Baseplate of Lactobacillus delbrueckii Bacteriophage Ld17 Harbors a Glycerophosphodiesterase*

C. Cambillau, S. Spinelli, D. van Sinderen, 2016, The Journal of Biological Chemistry.

Crystal structure of Bacillus subtilis SPP1 phage gp22 shares fold similarity with a domain of lactococcal phage p2 RBP

D. Veesler, C. Cambillau, S. Spinelli, 2010, Protein science : a publication of the Protein Society.

Structural Insights into Lactococcal Siphophage p2 Baseplate Activation Mechanism

C. Cambillau, S. Spinelli, S. Moineau, 2020, Viruses.

Deswapping bovine odorant binding protein.

C. Cambillau, S. Spinelli, E. Merli, 2008, Biochimica et biophysica acta.

Treatment for long bone metastases based on a systematic literature review

S. Spinelli, N. Baldini, A. Mavrogenis, 2017, European Journal of Orthopaedic Surgery & Traumatology.

Camelid heavy-chain variable domains provide efficient combining sites to haptens.

C. Cambillau, S. Spinelli, L. Frenken, 2000, Biochemistry.

Structure of human pancreatic lipase-related protein 2 with the lid in an open conformation.

C. Cambillau, S. Spinelli, J. Walker, 2008, Biochemistry.

Crystal Structure of the Receptor-Binding Protein Head Domain from Lactococcus lactis Phage bIL170

C. Cambillau, S. Spinelli, V. Campanacci, 2006, Journal of Virology.

Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV).

R. Garrett, H. van Tilbeurgh, C. Cambillau, 2006, Acta Crystallographica. Section F : Structural Biology and Crystallization Communications.

Monoclonal Ig L chain and L chain V domain fragment crystallization in myeloma-associated Fanconi's syndrome.

A. Khamlichi, M. Cogné, S. Spinelli, 1993, Journal of immunology.

Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase.

B. Coutard, C. Cambillau, S. Spinelli, 2007, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallization of antibody fragments and their complexes with antigen

R. Poljak, S. Spinelli, R. Mariuzza, 1988 .

Moineau, Christian Cambillau and Valérie Campanacci Lactococcal Phages Binding Protein Constructed from Two Crystal Structure of a Chimeric Receptor Supplemental Material

C. Cambillau, S. Spinelli, V. Campanacci, 2008 .

Combining site-specific mutagenesis and seeding as a strategy to crystallize 'difficult' proteins: the case of Staphylococcus aureus thioredoxin.

L. Wyns, A. Desmyter, S. Spinelli, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Liquid Biopsy in Cancer: Focus on Lymphoproliferative Disorders

S. Spinelli, A. Roccaro, A. Sacco, 2022, Cancers.

Cloning, bacterial expression and crystallization of Fv antibody fragments

T. Bhat, R. Poljak, S. Spinelli, 1992 .

Crystallization and preliminary diffraction analysis of the catalytic domain of xylanase Z from Clostridium thermocellum.

S. Spinelli, P. Alzari, H. Souchon, 1994, Journal of molecular biology.

Shampoo Prevention of Dandruff by Phage Display in Isolation of Llama Antibody Fragments for

C. Cambillau, S. Spinelli, L. Frenken, 2004 .

Camelid nanobodies: killing two birds with one stone.

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Current opinion in structural biology.

Reverse chemical ecology: Olfactory proteins from the giant panda and their interactions with putative pheromones and bamboo volatiles

S. Arena, A. Scaloni, C. Cambillau, 2017, Proceedings of the National Academy of Sciences.

The structure of an entire noncovalent immunoglobulin kappa light-chain dimer (Bence-Jones protein) reveals a weak and unusual constant domains association.

J. Navaza, C. Cambillau, S. Spinelli, 1999, European journal of biochemistry.

Crystal Structure of the Open Form of Dog Gastric Lipase in Complex with a Phosphonate Inhibitor*

P. Berna, R. Verger, C. Cambillau, 2002, The Journal of Biological Chemistry.

X‐ray structure of a superinfection exclusion lipoprotein from phage TP‐J34 and identification of the tape measure protein as its target

H. Neve, C. Cambillau, S. Spinelli, 2013, Molecular microbiology.

Complexes of porcine odorant binding protein with odorant molecules belonging to different chemical classes.

C. Cambillau, S. Spinelli, P. Pelosi, 2000, Journal of molecular biology.

Domain swapping creates a third putative combining site in bovine odorant binding protein dimer

C. Cambillau, S. Spinelli, E. Bignetti, 1996, Nature Structural Biology.

Boar salivary lipocalin

C. Cambillau, S. Spinelli, P. Pelosi, 2002 .

Three-dimensional X-ray structure and androstenol/androstenone docking simulations

C. Cambillau, S. Spinelli, P. Pelosi, 2002 .

Mammalian odorant binding proteins.

C Cambillau, C. Cambillau, S. Spinelli, 2000, Biochimica et biophysica acta.

Cas9 Allosteric Inhibition by the Anti-CRISPR Protein AcrIIA6.

M. Bolognesi, Y. Doyon, C. Cambillau, 2019, Molecular cell.

Structural basis of sialyltransferase activity in trypanosomal sialidases

A. Frasch, S. Spinelli, P. Alzari, 2000 .

Crystal structure of a ternary complex between human chorionic gonadotropin (hCG) and two Fv fragments specific for the alpha and beta-subunits.

C. Cambillau, S. Spinelli, M. Verhoeyen, 1999, Journal of molecular biology.

The importance of framework residues H6, H7 and H10 in antibody heavy chains: experimental evidence for a new structural subclassification of antibody V(H) domains.

A. Plückthun, C. Cambillau, A. Honegger, 2001, Journal of molecular biology.

Crystal structure of aphrodisin, a sex pheromone from female hamster.

P. Grote, C. Cambillau, S. Spinelli, 2001, Journal of molecular biology.

Modular Structure of the Receptor Binding Proteins of Lactococcus lactis Phages

Sylvain Moineau, Mariella Tegoni, Christian Cambillau, 2006, Journal of Biological Chemistry.

Three‐dimensional structure determination of an anti‐2‐phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response.

C. Milstein, R. Poljak, S. Spinelli, 1990, The EMBO journal.

Structural implications of somatic mutations during the immune response to 2-phenyloxazolone.

S. Spinelli, P. Alzari, 1994, Research in immunology.

Three-dimensional structure and antigen binding specificity of antibodies.

T. Bhat, M. Lascombe, R. Poljak, 1990, Biochimie.

Crystal structure of the allosteric-defective chaperonin GroEL E434K mutant

S. Spinelli, A. Muga, A. Mechaly, 2011 .

Structural basis of the honey bee PBP pheromone and pH-induced conformational change.

C. Cambillau, S. Spinelli, L. Briand, 2008, Journal of molecular biology.

Structural basis of sialyltransferase activity in trypanosomal sialidases.

A. Frasch, S. Spinelli, P. Alzari, 2000, The EMBO journal.

Insight into odorant perception: the crystal structure and binding characteristics of antibody fragments directed against the musk odorant traseolide.

A. Plückthun, C. Cambillau, A. Honegger, 1999, Journal of molecular biology.

Cryo-Electron Microscopy Structure of Lactococcal Siphophage 1358 Virion

C. Cambillau, S. Spinelli, B. Klaholz, 2014, Journal of Virology.

Bivalent Llama Single-Domain Antibody Fragments against Tumor Necrosis Factor Have Picomolar Potencies due to Intramolecular Interactions

A. Desmyter, C. Cambillau, S. Spinelli, 2017, Front. Immunol..

Crystal Structure and Function of a DARPin Neutralizing Inhibitor of Lactococcal Phage TP901-1

Andreas Plückthun, Sylvain Moineau, Mariella Tegoni, 2009, The Journal of Biological Chemistry.

Functional and structural dissection of the tape measure protein of lactococcal phage TP901-1

D. Sinderen, C. Cambillau, S. Spinelli, 2016, Scientific Reports.

Occurrence, integrity and functionality of AcaML1-like viruses infecting extreme acidophiles of the Acidithiobacillus species complex.

Paulo C. Covarrubias, S. Spinelli, Francisco Moya-Flores, 2018, Research in microbiology.

Crystal structure of a cohesin module from Clostridium cellulolyticum: implications for dockerin recognition.

C Cambillau, B Henrissat, B. Henrissat, 2000, Journal of molecular biology.

The crystal structure of odorant binding protein 7 from Anopheles gambiae exhibits an outstanding adaptability of its binding site.

C. Cambillau, S. Spinelli, Jing-Jiang Zhou, 2011, Journal of molecular biology.

Structure and activity of AbiQ, a lactococcal endoribonuclease belonging to the type III toxin–antitoxin system

Sylvain Moineau, Christian Cambillau, C. Cambillau, 2013, Molecular microbiology.

Structure of the phage TP901-1 1.8 MDa baseplate suggests an alternative host adhesion mechanism

D. Veesler, G. Bricogne, C. Cambillau, 2012, Proceedings of the National Academy of Sciences.

Viral infection modulation and neutralization by camelid nanobodies

A. Desmyter, D. Veesler, C. Cambillau, 2013, Proceedings of the National Academy of Sciences.

A mutation designed to alter crystal packing permits structural analysis of a tight‐binding fluorescein–scFv complex

A. Plückthun, C. Cambillau, A. Honegger, 2005, Protein science : a publication of the Protein Society.

Lateral recognition of a dye hapten by a llama VHH domain.

C. Cambillau, S. Spinelli, L. Frenken, 2001, Journal of molecular biology.

The crystal structure of a llama heavy chain variable domain

Dominique Bourgeois, Christian Cambillau, D. Bourgeois, 1996, Nature Structural Biology.

Crystal structures of bovine odorant-binding protein in complex with odorant molecules.

C. Cambillau, S. Spinelli, M. Tegoni, 2004, European journal of biochemistry.

Camelid nanobodies raised against an integral membrane enzyme, nitric oxide reductase

A. Desmyter, S. Muyldermans, C. Cambillau, 2009, Protein science : a publication of the Protein Society.

Kinetics and interaction studies between cytochrome c3 and Fe‐only hydrogenase from Desulfovibrio vulgaris hildenborough

S. Spinelli, M. Bruschi, M. Tegoni, 1998, Proteins.

The crystal structure of ORF14 from Sulfolobus islandicus filamentous virus

H. van Tilbeurgh, C. Cambillau, S. Spinelli, 2009, Proteins.

The thermo‐ and acido‐stable ORF‐99 from the archaeal virus AFV1

H. van Tilbeurgh, C. Cambillau, S. Spinelli, 2009, Protein science : a publication of the Protein Society.

Phase transition and amyloid formation by a viral protein as an additional molecular mechanism of virus-induced cell toxicity

S. Spinelli, Priscila Sutto-Ortiz, S. Longhi, 2018 .

Neutralization of Human Interleukin 23 by Multivalent Nanobodies Explained by the Structure of Cytokine–Nanobody Complex

A. Desmyter, C. Cambillau, S. Spinelli, 2017, Front. Immunol..

Direct in Vivo Screening of Intrabody Libraries Constructed on a Highly Stable Single-chain Framework*

Annemarie Honegger, Christian Cambillau, A. Plückthun, 2002, The Journal of Biological Chemistry.

A medium-throughput crystallization approach.

Renaud Vincentelli, Alain Roussel, Eric Blanc, 2002, Acta crystallographica. Section D, Biological crystallography.

Selection, characterization and x-ray structure of anti-ampicillin single-chain Fv fragments from phage-displayed murine antibody libraries.

A. Plückthun, C. Cambillau, A. Honegger, 2001, Journal of molecular biology.

The crystal structure of the Escherichia coli lipocalin Blc suggests a possible role in phospholipid binding

D. Nurizzo, C. Cambillau, S. Spinelli, 2004, FEBS letters.

Revisiting the host adhesion determinants of Streptococcus thermophilus siphophages

C. Cambillau, S. Spinelli, D. van Sinderen, 2020, Microbial biotechnology.

Conserved and Diverse Traits of Adhesion Devices from Siphoviridae Recognizing Proteinaceous or Saccharidic Receptors

C. Cambillau, S. Spinelli, J. Mahony, 2020, Viruses.

Molecular Insights on the Recognition of a Lactococcus lactis Cell Wall Pellicle by the Phage 1358 Receptor Binding Protein

C. Cambillau, S. Spinelli, S. Moineau, 2014, Journal of Virology.

Structure and Assembly of TP901-1 Virion Unveiled by Mutagenesis

C. Cambillau, S. Spinelli, D. van Sinderen, 2015, PloS one.

Crystal structure of the temperature-sensitive and allosteric-defective chaperonin GroELE461K.

S. Spinelli, A. Muga, A. Mechaly, 2006, Journal of structural biology.

Structure of a pancreatic α‐amylase bound to a substrate analogue at 2.03 Å resolution

S. Spinelli, F. Payan, M. Qian, 1997, Protein science : a publication of the Protein Society.

Structures and host-adhesion mechanisms of lactococcal siphophages

Christian Cambillau, David Veesler, D. Veesler, 2014, Front. Microbiol..

Structure and Molecular Assignment of Lactococcal Phage TP901-1 Baseplate*

M. van Heel, D. Veesler, C. Cambillau, 2010, The Journal of Biological Chemistry.

Laminin alpha2 chain-positive vessels and epidermal growth factor in lung neuroendocrine carcinoma: a model of a novel cooperative role of laminin-2 and epidermal growth factor in vessel neoplastic invasion and metastasis.

G. F. Coloni, S. Spinelli, P. Natali, 2006, The American journal of pathology.

Crystal structure of E.coli alcohol dehydrogenase YqhD: evidence of a covalently modified NADP coenzyme.

H. Eklund, C. Cambillau, S. Spinelli, 2004, Journal of molecular biology.

A common protein fold and similar active site in two distinct families of β-glycanases

Zbigniew Dauter, Roberto Dominguez, Keith S. Wilson, 1996, Nature Structural Biology.

Combining somatic mutations present in different in vivo affinity-matured antibodies isolated from immunized Lama glama yields ultra-potent antibody therapeutics.

A. Desmyter, C. Cambillau, S. Spinelli, 2016, Protein engineering, design & selection : PEDS.

Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release.

C. Cambillau, S. Spinelli, L. Briand, 2009, Journal of molecular biology.

Camelid Heavy-Chain Variable Domains Provide Efficient Combining Sites to Haptens†

C. Cambillau, S. Spinelli, L. Frenken, 2000 .

Inhibition of Type VI Secretion by an Anti-TssM Llama Nanobody

A. Desmyter, C. Cambillau, S. Spinelli, 2015, PloS one.

Anchoring the T6SS to the cell wall: Crystal structure of the peptidoglycan binding domain of the TagL accessory protein

C. Cambillau, S. Spinelli, A. Roussel, 2021, PloS one.

The structure of the monomeric porcine odorant binding protein sheds light on the domain swapping mechanism.

C Cambillau, C. Cambillau, S. Spinelli, 1998, Biochemistry.

The three-dimensional structure of the aspartyl protease from the HIV-1 isolate BRU.

R. Poljak, S. Spinelli, P. Alzari, 1991, Biochimie.

The Escherichia coli YadB gene product reveals a novel aminoacyl-tRNA synthetase like activity.

R. Vincentelli, R. Giegé, C. Cambillau, 2004, Journal of molecular biology.

Production, crystallization and X-ray diffraction analysis of a complex between a fragment of the TssM T6SS protein and a camelid nanobody.

A. Desmyter, C. Cambillau, S. Spinelli, 2015, Acta crystallographica. Section F, Structural biology communications.

Recombinant chemosensory protein (CSP2) from the moth Mamestra brassicae: crystallization and preliminary crystallographic study.

C. Cambillau, S. Spinelli, V. Campanacci, 2001, Acta crystallographica. Section D, Biological crystallography.

The targeted recognition of Lactococcus lactis phages to their polysaccharide receptors

C. Cambillau, S. Spinelli, S. Moineau, 2015, Molecular microbiology.

The Crystal Structure of a Cockroach Pheromone-binding Protein Suggests a New Ligand Binding and Release Mechanism*

C. Cambillau, S. Spinelli, A. Gruez, 2003, Journal of Biological Chemistry.

Crystal structure and function of a DARPin neutralizing inhibitor of lactococcal phage TP901-1: comparison of DARPin and camelid VHH binding mode

A. Plückthun, D. Veesler, C. Cambillau, 2010 .

Three‐dimensional structure determination of an anti‐2‐phenyloxazolone antibody: the role of somatic mutation and heavy/light chain pairing in the maturation of an immune response.

C. Milstein, R. Poljak, S. Spinelli, 1990, The EMBO journal.

Crystal structure of a complex between bovine chymotrypsin and ecotin

C. Cambillau, S. Spinelli, M. Lauwereys, 2002 .

Structure of odorant binding proteins and chemosensory proteins determined by X-ray crystallography.

C. Cambillau, S. Spinelli, B. Amigues, 2020, Methods in enzymology.

Domain swapping of a llama VHH domain builds a crystal-wide beta-sheet structure.

A. Desmyter, C. Cambillau, S. Spinelli, 2004, FEBS letters.

Lactococcus lactis phage TP901–1 as a model for Siphoviridae virion assembly

C. Cambillau, S. Spinelli, D. van Sinderen, 2016, Bacteriophage.

Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein

A. Desmyter, C. Cambillau, S. Spinelli, 2005 .

A topological model of the baseplate of lactococcal phage Tuc2009

G. Sciara, D. Sinderen, C. Cambillau, 2008 .

Crystal Structure of the Receptor-Binding Protein Head Domain from Lactococcus lactis Phage bIL 170

C. Cambillau, S. Spinelli, V. Campanacci, 2006 .

Multiple crystal forms of endoglucanase CelD: signal peptide residues modulate lattice formation.

S. Spinelli, P. Alzari, M. Juy, 1995, Journal of molecular biology.

Odorant Binding Protein 7 from Anopheles gambiae with Four Disulfide Bridges, form P1

C. Cambillau, S. Spinelli, Jing-Jiang Zhou, 2011 .