H. Krude

T. Schöneberg, H. Krude, T. Niemeyer, 2012, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Gamma-glutamyl Transferase Is Strongly Associated With Degree of Overweight and Sex

S. Wiegand, H. Krude, T. Reinehr, 2011, Journal of pediatric gastroenterology and nutrition.

Proopiomelanocortin Deficiency Treated with a Melanocortin-4 Receptor Agonist.

K. Clément, A. Grüters, S. Wiegand, 2016, The New England journal of medicine.

Childhood obesity.

A. Eliakim, S. Shalitin, H. Krude, 2005, The Journal of clinical endocrinology and metabolism.

An Integrated Understanding of the Molecular Mechanisms of How Adipose Tissue Metabolism Affects Long-term Body Weight Maintenance

N. Hübner, S. Wiegand, H. Krude, 2018, Diabetes.

Effects of a combined dietary, exercise and behavioral intervention and sympathetic system on body weight maintenance after intended weight loss: Results of a randomized controlled trial.

H. Krude, J. Spranger, K. Mai, 2018, Metabolism: clinical and experimental.

ANP system activity predicts variability of fat mass reduction and insulin sensitivity during weight loss.

N. Hübner, S. Wiegand, H. Krude, 2016, Metabolism: clinical and experimental.

Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants

H. Wichmann, T. Illig, H. Grallert, 2012, BMC Medical Genomics.

Interaction of circulating GLP-1 and the response of the dorsolateral prefrontal cortex to food-cues predicts body weight development

J. Haynes, M. Weygandt, H. Krude, 2019, Molecular metabolism.

Evidence of G-protein-coupled receptor and substrate transporter heteromerization at a single molecule level

Catherine L. Worth, B. Wiesner, H. Biebermann, 2017, Cellular and Molecular Life Sciences.

Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum

H. Ropers, H. Christen, A. Grüters, 2014, Journal of Medical Genetics.

Hormonal regulatory mechanisms in obese children and adolescents after previous weight reduction with a lifestyle intervention: maintain - paediatric part - a RCT from 2009–15

S. Wiegand, H. Krude, A. Ernert, 2016, BMC Obesity.

Implications of Proopiomelanocortin (POMC) Mutations in Humans: The POMC Deficiency Syndrome

A. Grüters, H. Krude, 2000, Trends in Endocrinology & Metabolism.

Differential Signaling Profiles of MC4R Mutations with Three Different Ligands

M. Lohse, P. Annibale, H. Biebermann, 2020, International journal of molecular sciences.

Melanocortin-4 Receptor Signalling: Importance for Weight Regulation and Obesity Treatment.

H. Biebermann, H. Krude, P. Kühnen, 2019, Trends in molecular medicine.

Rescue of Melanocortin 4 Receptor (MC4R) Nonsense Mutations by Aminoglycoside‐Mediated Read‐Through

J. Hebebrand, A. Hinney, A. Grüters, 2012, Obesity.

Mutationally Induced Disulfide Bond Formation within the Third Extracellular Loop Causes Melanocortin 4 Receptor Inactivation in Patients with Obesity*

T. Schöneberg, A. Grüters, H. Biebermann, 2003, Journal of Biological Chemistry.

Analysis of the Wilms' tumor suppressor gene (WT1) in patients 46,XY disorders of sex development.

A. Grüters, H. Biebermann, H. Krude, 2011, The Journal of clinical endocrinology and metabolism.

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency.

A. von Deimling, A. Grüters, H. Biebermann, 2002, The Journal of clinical investigation.

Evolution, child development and the thyroid: a phylogenetic and ontogenetic introduction to normal thyroid function.

H. Krude, 2014, Endocrine development.

Ring Finger Protein 11 Inhibits Melanocortin 3 and 4 Receptor Signaling

M. Tschöp, A. Grüters, H. Biebermann, 2016, Front. Endocrinol..

Proinsulin and the proinsulin/insulin ratio in overweight and obese children and adolescents: relation to clinical parameters, insulin resistance, and impaired glucose regulation

H. Biebermann, S. Wiegand, H. Krude, 2011, Pediatric diabetes.

Movement disorders in MCT8 deficiency/Allan-Herndon-Dudley Syndrome.

H. Krude, S. Orcesi, O. Boespflug-Tanguy, 2021, Molecular genetics and metabolism.

Neonatal Thyroid Disorders

A. Grüters, H. Biebermann, H. Krude, 2003, Hormone Research in Paediatrics.

Arteries define the position of the thyroid gland during its developmental relocalisation

S. Mundlos, A. Grüters, H. Krude, 2006, Development.

A role for β-melanocyte-stimulating hormone in human body-weight regulation

M. Tschöp, J. Hebebrand, A. Hinney, 2006 .

Detection of Novel Gene Variants Associated with Congenital Hypothyroidism in a Finnish Patient Cohort

M. Laakso, J. Toppari, H. Biebermann, 2016, Thyroid : official journal of the American Thyroid Association.

European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism

M. Polak, H. Krude, J. Léger, 2014, Hormone Research in Paediatrics.

European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism

M. Polak, H. Krude, J. Léger, 2014, The Journal of clinical endocrinology and metabolism.

Melanocortin 4 receptor mutations become common.

H. Biebermann, H. Krude, P. Kühnen, 2021, Cell metabolism.

Mutually opposite signal modulation by hypothalamic heterodimerization of ghrelin- and melanocortin-3 receptors

T. Schöneberg, M. Tschöp, A. Grüters, 2012 .

Mutations in the Human Proopiomelanocortin Gene

A. Grüters, H. Biebermann, H. Krude, 2003, Annals of the New York Academy of Sciences.

A role for b-melanocyte-stimulating hormone in human bodyweight regulation

M. Tschöp, J. Hebebrand, A. Hinney, 2022 .

Constitutively activating TSH-receptor mutations as a molecular cause of non-autoimmune hyperthyroidism in childhood

T. Gudermann, T. Schöneberg, A. Grüters, 2000, Langenbeck's Archives of Surgery.

Alterations of neonatal thyroid function

T. Schöneberg, A. Grüters, H. Biebermann, 1999, Acta paediatrica (Oslo, Norway : 1992). Supplement.

Differential Modulation of Beta-Adrenergic Receptor Signaling by Trace Amine-Associated Receptor 1 Agonists

T. Schöneberg, A. Grüters, H. Biebermann, 2011, PloS one.

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

A. Uitterlinden, T. Visser, H. Biebermann, 2004, The Lancet.

The paediatric Confusion Assessment Method for the Intensive Care Unit (pCAM-ICU): Translation and cognitive debriefing for the German-speaking area

E. Ely, H. Krude, C. Spies, 2012, German medical science : GMS e-journal.

Association of variants in gastric inhibitory polypeptide receptor gene with impaired glucose homeostasis in obese children and adolescents from Berlin.

T. Illig, H. Grallert, J. Hebebrand, 2010, European journal of endocrinology.

Severe Acquired Primary Hypothyroidism in Children and its Influence on Growth: A Retrospective Analysis of 43 Cases.

H. Krude, D. Schnabel, E. Lankes, 2021, Experimental and clinical endocrinology & diabetes.

Glucose-Dependent Insulinotropic Polypeptide Reduces Fat-Specific Expression and Activity of 11β-Hydroxysteroid Dehydrogenase Type 1 and Inhibits Release of Free Fatty Acids

A. Pfeiffer, H. Krude, U. Kintscher, 2012, Diabetes.

DB100902 292..300

A. Pfeiffer, H. Krude, U. Kintscher, 2012 .

The orphan receptor Gpr83 regulates systemic energy metabolism via ghrelin-dependent and ghrelin-independent mechanisms

S. Woods, P. Pfluger, M. Tschöp, 2013, Nature Communications.

An incretin-based tri-agonist promotes superior insulin secretion from murine pancreatic islets via PLC activation.

T. Gudermann, M. Tschöp, H. Biebermann, 2018, Cellular signalling.

Clinical concepts in childhood thyroid cancer Ultrasound screening for thyroid carcinoma in childhood cancer survivors : a case series

H. Krude, 2009 .

3-iodothyronamine differentially modulates α-2A-adrenergic receptor-mediated signaling.

T. Schöneberg, A. Grüters, H. Biebermann, 2015, Journal of molecular endocrinology.

Insights into molecular properties of the human monocarboxylate transporter 8 by combining functional with structural information

A. Grüters, H. Biebermann, H. Krude, 2011, Thyroid research.

G-Protein Coupled Receptor 83 (GPR83) Signaling Determined by Constitutive and Zinc(II)-Induced Activity

M. Tschöp, A. Grüters, H. Biebermann, 2013, PloS one.

What is the Role of Thyroid Hormone Receptor Alpha 2 (TRα2) in Human Physiology?

H. Krude, Marc Schuelke, Sarah Paisdzior, 2022, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Spatiotemporal Changes of Cerebral Monocarboxylate Transporter 8 Expression.

I. Bechmann, H. Biebermann, H. Krude, 2020, Thyroid : official journal of the American Thyroid Association.

Long-term consequences of congenital hypothyroidism in the era of screening programmes.

A. Grüters, H. Krude, A. Jenner, 2002, Best practice & research. Clinical endocrinology & metabolism.

Molecular description of non-autoimmune hyperthyroidism at a neonate caused by a new thyrotropin receptor germline mutation

A. Grüters, H. Biebermann, H. Krude, 2011, Thyroid research.

A role for beta-melanocyte-stimulating hormone in human body-weight regulation.

A. von Deimling, M. Tschöp, J. Hebebrand, 2006, Cell metabolism.

Gender identity disorders in childhood and adolescence: currently debated concepts and treatment strategies.

H. Krude, K. Beier, U. Lehmkuhl, 2008, Deutsches Arzteblatt international.

Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome

H. Fuchs, A. Feuchtinger, W. Wurst, 2022, Molecular metabolism.

Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss.

M. Dattani, D. Gerrelli, H. Biebermann, 2008, Human molecular genetics.

Mutations in LHX3 result in a new syndrome revealed by combined pituitary hormone deficiency

A. Grüters, H. Krude, S. Amselem, 2000, Nature Genetics.

Molecular genetic defects in congenital hypothyroidism.

A. Grüters, H. Biebermann, H. Krude, 2004, European journal of endocrinology.

Fatal neonatal respiratory failure in an infant with congenital hypothyroidism due to haploinsufficiency of the NKX2-1 gene: alteration of pulmonary surfactant homeostasis

H. Krude, G. Schmitz, A. Holzinger, 2010, Archives of Disease in Childhood: Fetal and Neonatal Edition.

Detection and treatment of congenital hypothyroidism

A. Grüters, H. Krude, 2012, Nature Reviews Endocrinology.

Detection and treatment of congenital

H. Krude, 2011 .

Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.

A. Grüters, H. Krude, M. D. de Angelis, 2011, European journal of endocrinology.

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

A. Grüters, H. Biebermann, H. Krude, 1998, Nature Genetics.

Consensus statement : Childhood obesity

Henry Anhalt, Cecilia Camacho-Hübner, Robert H. Lustig, 2005 .

Obesity due to proopiomelanocortin deficiency: three new cases and treatment trials with thyroid hormone and ACTH4-10.

A. Grüters, H. Biebermann, H. Krude, 2003, The Journal of clinical endocrinology and metabolism.

Implications of the Phenotype of POMC Deficiency for the Role of POMC‐Derived Peptides in Skin Physiology

A. Grüters, H. Krude, W. Luck, 1999, Annals of the New York Academy of Sciences.

Number and topography of epitopes of human chorionic gonadotropin (hCG) are shared by desialylated and deglycosylated hCG

H. Krude, S. Dirnhofer, S. Schwarz, 1991, Molecular and Cellular Endocrinology.

RELATIONSHIP OF ORIENTATION WITH AFFINITY AND ACTIVITY OF GONADOTROPIN (hCG), AS VISUALIZED BY MONOCLONAL ANTIBODIES (MCA)

H. Krude, S. Schwarz, G. Wick, 1991 .

Relationship of orientation with affinity and activity of receptor-bound glycosylation variants of human chorionic gonadotropin (hCG), as visualized by monoclonal antibodies (MCA).

H. Krude, S. Schwarz, G. Wick, 1991, Journal of receptor research.

Testosterone production during puberty in two 46,XY patients with disorders of sex development and novel NR5A1 (SF-1) mutations

H. Biebermann, H. Krude, B. Köhler, 2012, European journal of endocrinology.

Twelve of fourteen surface epitopes of receptor-bound human chorionic gonadotropin (hCG) being antibody-inaccessible suggest an extensive involvement of the long extracellular domain of the hCG receptor

H. Krude, S. Schwarz, G. Wick, 1991, Molecular and Cellular Endocrinology.

Epitope mapping of the receptor-bound agonistic form of human chorionic gonadotropin (hCG) in comparison to the antagonistic form (deglycosylated hCG).

H. Krude, G. Wick, P. Berger, 1991, Biochemical and biophysical research communications.

Novel insights on thyroid-stimulating hormone receptor signal transduction.

A. Grüters, H. Biebermann, H. Krude, 2013, Endocrine reviews.

Analysis of the gene coding for steroidogenic factor 1 (SF1, NR5A1) in a cohort of 50 Egyptian patients with 46,XY disorders of sex development.

A. Grüters, H. Biebermann, H. Krude, 2014, European journal of endocrinology.

2022 European Thyroid Association Guidelines for the management of pediatric thyroid nodules and differentiated thyroid carcinoma

M. Luster, H. Krude, T. Takano, 2022, European thyroid journal.

Treatment of congenital thyroid dysfunction: Achievements and challenges.

H. Biebermann, H. Krude, P. Kühnen, 2015, Best practice & research. Clinical endocrinology & metabolism.

A Novel Hemizygous Mutation of MAMLD1 in a Patient with 46,XY Complete Gonadal Dysgenesis

A. Grüters, H. Biebermann, H. Krude, 2015, Sexual Development.

A Prospective Study of Children Aged 0–8 Years with CAH and Adrenal Insufficiency Treated with Hydrocortisone Granules

S. Wiegand, H. Krude, K. Braune, 2020, The Journal of clinical endocrinology and metabolism.

Homozygous nonsense and frameshift mutations of the ACTH receptor in children with familial glucocorticoid deficiency (FGD) are not associated with long-term mineralocorticoid deficiency

H. Krude, L. Metherell, M. Savage, 2009, Clinical endocrinology.

Thyroid dysfunction in pregnancy

H. Krude, J. Kratzsch, D. Führer, 2015 .

Septo‐optic dysplasia associated with a new mitochondrial cytochrome b mutation

M. Schuelke, H. Krude, J. Smeitink, 2002, Annals of neurology.

Congenital Hypothyroidism: A 2020–2021 Consensus Guidelines Update—An ENDO-European Reference Network Initiative Endorsed by the European Society for Pediatric Endocrinology and the European Society for Endocrinology

D. Luton, M. Polak, H. Krude, 2020, Thyroid : official journal of the American Thyroid Association.

Autosomal-dominant mode of inheritance of a melanocortin-4 receptor mutation in a patient with severe early-onset obesity is due to a dominant-negative effect caused by receptor dimerization.

T. Gudermann, A. Grüters, H. Biebermann, 2003, Diabetes.

Is there a further acceleration in the age at onset of menarche? A cross-sectional study in 1840 school children focusing on age and bodyweight at the onset of menarche.

A. Grüters, S. Wiegand, H. Krude, 2009, European journal of endocrinology.

The Thyroid and Its Regulation by the TSHR: Evolution, Development, and Congenital Defects

H. Biebermann, H. Krude, 2019, The Thyroid and Its Diseases.

Molecular Pathogenesis of Neonatal Hypothyroidism

A. Grüters, H. Biebermann, H. Krude, 2000, Hormone Research in Paediatrics.

MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency

K. Clément, A. Grüters, H. Biebermann, 2018, Nature Medicine.

A New Mechanism in THRA Resistance: The First Disease-Associated Variant Leading to an Increased Inhibitory Function of THRA2

M. Schuelke, H. Biebermann, H. Krude, 2021, International journal of molecular sciences.

Signal Transduction and Pathogenic Modifications at the Melanocortin-4 Receptor: A Structural Perspective

H. Biebermann, H. Krude, M. Szczepek, 2019, Front. Endocrinol..

PAX8 mutations associated with congenital hypothyroidism caused by thyroid dysgenesis

Luca Chiovato, P. Macchia, R. Lauro, 1998, Nature Genetics.

Sleep Timing in Patients with Precocious and Delayed Pubertal Development

S. Wiegand, H. Krude, C. Vetter, 2019, Clocks & sleep.

Identification of PENDRIN (SLC26A4) mutations in patients with congenital hypothyroidism and "apparent" thyroid dysgenesis.

A. Grüters, H. Biebermann, H. Krude, 2014, The Journal of clinical endocrinology and metabolism.

Mutations in TITF-1 are associated with benign hereditary chorea.

B. D. de Vries, M. MacDonald, W. Arts, 2002, Human molecular genetics.

An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

T. Keil, S. Lau, Young-Ae Lee, 2012, PLoS genetics.

What can go wrong in the non-coding genome and how to interpret whole genome sequencing data

S. Mundlos, N. C. Øien, M. Schuelke, 2021, Medizinische Genetik.

A New Multisystem Disorder Caused by the G&agr;s Mutation p.F376V

M. Dattani, A. Grüters, H. Biebermann, 2018, The Journal of clinical endocrinology and metabolism.

Screening chromosomal aberrations by array comparative genomic hybridization in 80 patients with congenital hypothyroidism and thyroid dysgenesis.

H. Biebermann, H. Krude, R. Ullmann, 2010, The Journal of clinical endocrinology and metabolism.

How a patient homozygous for a 30-kb deletion of the C4-CYP 21 genomic region can have a nonclassic form of 21-hydroxylase deficiency.

A. Grüters, H. Krude, V. Tardy, 2000, The Journal of clinical endocrinology and metabolism.

No correlation between androgen receptor CAG and GGN repeat length and the degree of genital virilization in females with 21-hydroxylase deficiency.

H. Krude, G. Binder, H. Dörr, 2010, The Journal of clinical endocrinology and metabolism.

A new multi-system disorder caused by the Gαs mutation p.F376V

M. Dattani, A. Grüters, H. Biebermann, 2018 .

Allan-Herndon-Dudley-Syndrome: Considerations about the Brain Phenotype with Implications for Treatment Strategies.

M. Tschöp, M. Schuelke, H. Biebermann, 2020, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Treating patients not numbers: the benefit and burden of lowering TSH newborn screening cut-offs

H. Krude, O. Blankenstein, 2010, Archives of Disease in Childhood.

Target Diseases for Neonatal Screening in Germany-Challenges for Treatment and Long-Term Care.

H. Krude, U. Spiekerkoetter, 2022, Deutsches Arzteblatt international.

Do Common Variants Separate between Obese Melanocortin-4 Receptor Gene Mutation Carriers and Non-Carriers? The Impact of Cryptic Relatedness

T. Illig, H. Grallert, J. Hebebrand, 2012, Hormone Research in Paediatrics.

The neuroendocrine circuitry controlled by POMC, MSH, and AGRP.

H. Biebermann, H. Krude, G. Kleinau, 2012, Handbook of experimental pharmacology.

[Update of the S2k guidelines : Surgical treatment of benign thyroid diseases].

C. Nies, A. Bockisch, M. Luster, 2018, Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen.

Alu elements and human common diseases like obesity

H. Krude, P. Kuehnen, 2012, Mobile genetic elements.

Angeborene Hypothyreose

A. Grüters, H. Krude, 2008, Monatsschrift Kinderheilkunde.

The Use of L-T4 as Liquid Solution Improves the Practicability and Individualized Dosage in Newborns and Infants with Congenital Hypothyroidism

A. Grüters, H. Krude, D. L'Allemand, 2004, Journal of pediatric endocrinology & metabolism : JPEM.

Ongoing expression of Nkx2.1 in the postnatal mouse forebrain: Potential for understanding NKX2.1 haploinsufficiency in humans?

H. Krude, R. Nitsch, L. Magno, 2009, Brain Research.

The Interdisciplinary Diagnosis of Rare Diseases-Results of the Translate-NAMSE Project.

M. Nöthen, S. Mundlos, T. Meitinger, 2022, Deutsches Arzteblatt international.

Absorption and tolerability of taste‐masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency

S. Wiegand, H. Krude, R. Ross, 2018, Clinical endocrinology.

Development and testing in healthy adults of oral hydrocortisone granules with taste masking for the treatment of neonates and infants with adrenal insufficiency.

D. Eckland, G. Tucker, H. Krude, 2015, The Journal of clinical endocrinology and metabolism.

Absorption and tolerability of taste-masked hydrocortisone granules in neonates, infants and children under 6 years of age with adrenal insufficiency

S. Wiegand, H. Krude, R. Ross, 2019, Endocrine Abstracts.

Interindividual Variation in DNA Methylation at a Putative POMC Metastable Epiallele Is Associated with Obesity.

P. Dominguez-Salas, A. Prentice, F. Heppner, 2016, Cell metabolism.

Meta-Analysis of the INSIG2 Association with Obesity Including 74,345 Individuals: Does Heterogeneity of Estimates Relate to Study Design?

F. Kronenberg, M. McCarthy, F. Hu, 2009, PLoS genetics.

Severe transitory encephalopathy with reversible lesions of the claustrum

H. Krude, D. Scheffner, J. Sperner, 1996, Pediatric Radiology.

Mean High-Dose L-Thyroxine Treatment Is Efficient and Safe to Achieve a Normal IQ in Young Adult Patients With Congenital Hypothyroidism

A. Grüters, H. Krude, M. Craig, 2018, The Journal of clinical endocrinology and metabolism.

Heterodimerization of Hypothalamic G-Protein-Coupled Receptors Involved in Weight Regulation

A. Grüters, H. Biebermann, H. Krude, 2009, Obesity Facts.

Metformin and placebo therapy both improve weight management and fasting insulin in obese insulin-resistant adolescents: a prospective, placebo-controlled, randomized study.

A. Grüters, S. Wiegand, H. Krude, 2010, European journal of endocrinology.

H. Krude, S. Monti, A. Cassio, 2015, Italian Journal of Pediatrics.

HESX1 mutations are an uncommon cause of septooptic dysplasia and hypopituitarism.

M. Dattani, H. Krude, S. Shalet, 2007, The Journal of clinical endocrinology and metabolism.

A new phenotype of nongoitrous and nonautoimmune hyperthyroidism caused by a heterozygous thyrotropin receptor mutation in transmembrane helix 6.

A. Grüters, H. Biebermann, H. Krude, 2010, The Journal of clinical endocrinology and metabolism.

A novel mutation of LHX3 is associated with combined pituitary hormone deficiency including ACTH deficiency, sensorineural hearing loss, and short neck—a case report and review of the literature

H. Krude, W. Bonfig, H. Schmidt, 2011, European Journal of Pediatrics.

Update on the Management of Congenital Hypothyroidism

A. Grüters, H. Krude, 2007, Hormone Research in Paediatrics.

Mutation analysis of the MCHR1 gene in human obesity.

K. Huse, O. Pedersen, K. Clément, 2005, European journal of endocrinology.

An Integrated clinical pathway for diagnosis, treatment and care of rare diseases: model, operating procedures, and results of the project TRANSLATE-NAMSE funded by the German Federal Joint Committee

C. Klein, H. Krude, F. Hauck, 2021, Orphanet Journal of Rare Diseases.

Ethnicity and comorbidities in an overweight and obese multiethnic childhood cohort in Berlin

S. Wiegand, H. Krude, P. Martus, 2011, Acta paediatrica.

MC4R Dimerization in the Paraventricular Nucleus and GHSR/MC3R Heterodimerization in the Arcuate Nucleus: Is There Relevance for Body Weight Regulation?

M. Tschöp, A. Grüters, H. Biebermann, 2012, Neuroendocrinology.

Differences in taste sensitivity between obese and non-obese children and adolescents

Thomas Hummel, T. Hummel, S. Wiegand, 2012, Archives of Disease in Childhood.

Mutually Opposite Signal Modulation by Hypothalamic Heterodimerization of Ghrelin and Melanocortin-3 Receptors*

T. Schöneberg, M. Tschöp, A. Grüters, 2011, The Journal of Biological Chemistry.

Transition for adolescents with a rare disease: results of a nationwide German project

A. Grüters, H. Krude, F. Hauck, 2023, Orphanet Journal of Rare Diseases.

Surfactant proteins in pediatric interstitial lung disease

H. Krude, M. Griese, C. Aslanidis, 2016, Pediatric Research.

Inhibition of melanocortin-4 receptor dimerization by substitutions in intracellular loop 2.

A. Grüters, H. Biebermann, H. Krude, 2013, Journal of molecular endocrinology.

New pathogenic thyrotropin receptor mutations decipher differentiated activity switching at a conserved helix 6 motif of family A GPCR.

A. Grüters, B. Wiesner, H. Biebermann, 2012, The Journal of clinical endocrinology and metabolism.

Effectiveness and safety of the tri-iodothyronine analogue Triac in children and adults with MCT8 deficiency: an international, single-arm, open-label, phase 2 trial.

E. Bertini, F. Aarsen, L. de Meirleir, 2019, The lancet. Diabetes & endocrinology.

Inverse Agonistic Action of 3-Iodothyronamine at the Human Trace Amine-Associated Receptor 5

T. Schöneberg, M. Tschöp, A. Grüters, 2015, PloS one.

Investigation of Naturally Occurring Single-Nucleotide Variants in Human TAAR1

H. Völzke, G. Homuth, A. Teumer, 2017, Front. Pharmacol..

Disease characteristics of MCT8 deficiency: an international, retrospective, multicentre cohort study.

E. Bertini, N. Brunetti‐Pierri, M. Polak, 2020, The lancet. Diabetes & endocrinology.

MAINTAIN: an Intervention Study of Weight Regain After Weight Loss in Adolescents and Children Reveals an Only Minor Role of Leptin in Weight Regain

S. Wiegand, H. Krude, A. Ernert, 2014 .

Etiological grouping of permanent congenital hypothyroidism with a thyroid gland in situ.

A. Grüters, H. Krude, R. Finke, 1994, Hormone research.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Henrik, Tanya M. Teslovich, Jennie, 2012 .

Screening for mutations of the human thyroid peroxidase gene in patients with congenital hypothyroidism

A. Grüters, H. Biebermann, H. Krude, 1997, Experimental and clinical endocrinology & diabetes.

Two Puzzling Cases of Thyroid Dysgenesis

H. Krude, A. Grueters, P. Kuehnen, 2009, Hormone Research in Paediatrics.

The use of FDG-PET and CT for the staging of adrenocortical carcinoma in children

H. Amthauer, N. Hosten, H. Krude, 2000, Pediatric Radiology.

Contents Vol. 77, 2012

F. Kronenberg, V. Tillmann, T. Stijnen, 2012, Hormone Research in Paediatrics.

Diabetes caused by insulin gene (INS) deletion: clinical characteristics of homozygous and heterozygous individuals.

H. Krude, G. Werther, K. Raile, 2011, European journal of endocrinology.

The gene for the thyrotropin receptor (TSHR) as a candidate gene for congenital hypothyroidism with thyroid dysgenesis

W. Göpel, A. Grüters, H. Biebermann, 2009, Experimental and clinical endocrinology & diabetes.

Association analyses of 249 , 796 individuals reveal 18 new loci associated with body mass index

Tanya M. Teslovich, Eric, P. Elliott, 2012 .

Severe early-onset obesity, adrenal insufficiency and red hair pigmentation caused by POMC mutations in humans

A. Grüters, H. Biebermann, H. Krude, 1998, Nature Genetics.

Rescue of Melanocortin 4 Receptor (MC4R) Nonsense Mutations by Aminoglycoside‐Mediated Read‐Through

J. Hebebrand, A. Hinney, A. Grüters, 2012, Obesity.

Association analyses of 249,796 individuals reveal eighteen new loci associated with body mass index

Tanya M. Teslovich, M. Jarvelin, L. Coin, 2010, Nature genetics.

Diabetes caused by insulin gene (INS) deletion: clinical characteristics of homozygous and heterozygous individuals.

H. Krude, G. Werther, M. O’Connell, 2011, European journal of endocrinology.

Comprehensive genotyping and clinical characterisation reveal 27 novel NKX2-1 mutations and expand the phenotypic spectrum

H. Ropers, H. Christen, A. Grüters, 2014, Journal of Medical Genetics.

Analysis of the gene coding for steroidogenic factor 1 (SF1, NR5A1) in a cohort of 50 Egyptian patients with 46,XY disorders of sex development.

A. Grüters, H. Biebermann, H. Krude, 2014, European journal of endocrinology.

Gender identity disorders in childhood and adolescence: currently debated concepts and treatment strategies.

H. Krude, K. Beier, U. Lehmkuhl, 2008, Deutsches Arzteblatt international.

Evaluation of a rare glucose‐dependent insulinotropic polypeptide receptor variant in a patient with diabetes

H. Völzke, G. Homuth, A. Teumer, 2019, Diabetes, obesity & metabolism.

Ethnicity and comorbidities in an overweight and obese multiethnic childhood cohort in Berlin

H. Krude, A. Ernert, A. Dannemann, 2011, Acta paediatrica.

[Who needs what? New approaches to multidisciplinary diagnostics and therapy for adipose children and youths in a multiethnic city].

A. Grüters, S. Wiegand, H. Krude, 2005, Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz.

Monocarboxylate transporter 8 deficiency: altered thyroid morphology and persistent high triiodothyronine/thyroxine ratio after thyroidectomy.

A. Grüters, H. Krude, M. D. de Angelis, 2011, European journal of endocrinology.

Treatment of congenital hypothyroidism

H. Krude, 2017 .

Detection and treatment of congenital hypothyroidism

A. Grüters, H. Krude, 2012, Nature Reviews Endocrinology.

Clinical Practice Guideline: European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism

M. Polak, H. Krude, J. Léger, 2014 .

Congenital Hypothyroidism: A Historical Perspective on Cognitive Outcome

H. Krude, 2019, Encyclopedia of Endocrine Diseases.