M. Brewster

发表

Preparation and Characterization of Nanofibers Containing Amorphous Drug Dispersions Generated by Electrostatic Spinning

G. Verreck, I. Chun, J. Peeters, 2003, Pharmaceutical Research.

Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer.

Joel Rosenblatt, Geert Verreck, G. Verreck, 2003, Journal of controlled release : official journal of the Controlled Release Society.

Cyclodextrin-based pharmaceutics: past, present and future

Mark E. Davis, M. Brewster, 2004, Nature Reviews Drug Discovery.

Pharmaceutical applications of cyclodextrins: basic science and product development

M. Brewster, T. Loftsson, 2010, The Journal of pharmacy and pharmacology.

Evaluation of gastrointestinal drug supersaturation and precipitation: strategies and issues.

M. Brewster, P. Augustijns, J. Brouwers, 2013, International journal of pharmaceutics.

Pharmaceutical applications of cyclodextrins: effects on drug permeation through biological membranes

M. Brewster, T. Loftsson, 2011, The Journal of pharmacy and pharmacology.

Stable ciliary activity in human nasal epithelial cells grown in a perfusion system.

M. Brewster, M. Noppe, P. Augustijns, 2005, International journal of pharmaceutics.

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.

Mark McAllister, René Holm, Christel A. S. Bergström, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery.

Jef Adriaensen, Claire Mackie, M. Brewster, 2007, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Downstream processing of polymer-based amorphous solid dispersions to generate tablet formulations.

G. Marosi, Z. Nagy, G. Marosi, 2015, International journal of pharmaceutics.

Characterization of solid dispersions of itraconazole and hydroxypropylmethylcellulose prepared by melt extrusion--Part I.

Lieven Baert, Geert Verreck, G. Verreck, 2003, International journal of pharmaceutics.

Characterization of Solid Dispersions of Itraconazole and Hydroxypropylmethylcellulose Prepared by Melt Extrusion, Part II

Christian Leuner, Jules Mullens, Jennifer Dressman, 2003, Pharmaceutical Research.

Neural network studies 2. Use of a neural net to estimate oxidation energies for substituted dihydropyridines and related heterocycles

N. Bodor, A. Harget, M. Brewster, 1992 .

Evaluation of various PAMPA models to identify the most discriminating method for the prediction of BBB permeability.

G. Verreck, M. Brewster, J. Mensch, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Effect of the unstirred water layer on permeability enhancement by hydrophilic cyclodextrins.

J. Peeters, M. Brewster, M. Noppe, 2007, International journal of pharmaceutics.

Summary Report of PQRI Workshop on Nanomaterial in Drug Products: Current Experience and Management of Potential Risks

Celia N. Cruz, M. Brewster, R. Prud’homme, 2014, The AAPS Journal.

Active and passive tumor targeting of a novel poorly soluble cyclin dependent kinase inhibitor, JNJ-7706621.

M. Brewster, V. Préat, F. Danhier, 2010, International journal of pharmaceutics.

In vitro models for the prediction of in vivo performance of oral dosage forms.

Anette Müllertz, Patrick Augustijns, Bertil Abrahamsson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Tissue distribution of LY231617, an antioxidant with neuroprotectant activity, in the rat.

N. Bodor, M. Brewster, J. Panetta, 1995, Journal of pharmaceutical sciences.

Transfer of phosphatidylcholine facilitated by a component of human plasma.

J. Brainard, M. Brewster, J. Harmony, 1978, Biochimica et biophysica acta.

Complexation—Use of Cyclodextrins to Improve Pharmaceutical Properties of Intramuscular Formulations

M. Brewster, T. Loftsson, 1999 .

Drug Solubilization and Stabilization by Cyclodextrin Drug Carriers

M. Brewster, T. Loftsson, 2013 .

Supersaturating drug delivery systems: effect of hydrophilic cyclodextrins and other excipients on the formation and stabilization of supersaturated drug solutions.

G. Verreck, J. Peeters, M. Brewster, 2008, Die Pharmazie.

The use of human nasal in vitro cell systems during drug discovery and development.

M. Brewster, M. Noppe, P. Augustijns, 2005, Toxicology in vitro : an international journal published in association with BIBRA.

Characterization of self-assembling copolymers in aqueous solutions using Electron Paramagnetic Resonance and Fluorescence spectroscopy.

M. Brewster, V. Préat, B. Gallez, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Structural studies of loteprednol etabonate and other analogs of prednisolone using NMR techniques

M. Brewster, S. Rachwał, E. Pop, 1996, Steroids.

Cyclodextrin‐Enhanced Drug Delivery through Mucous Membranes

M. Brewster, T. Loftsson, P. Jansook, 2011 .

Effect of various cyclodextrins on solution stability and dissolution rate of doxorubicin hydrochloride

N. Bodor, M. Brewster, T. Loftsson, 1992 .

Alfaxalone: Effect of Temperature on Complexation with 2-Hydroxypropyl-β-cyclodextrin

M. Brewster, Jef Adriaensen, Jef Speeters, 2002 .

Complex Formation

M. Brewster, 2012 .

Safety-assessment of 3-methoxyquercetin as an antirhinoviral compound for nasal application: effect on ciliary beat frequency.

M. Brewster, M. Noppe, P. Augustijns, 2003, International journal of pharmaceutics.

The effects of a brain-enhanced estradiol delivery system on testosterone and androgen-dependent tissues. II. The role of testosterone.

N. Bodor, J. Simpkins, M. Brewster, 1991, Endocrinology.

The effects of a brain-enhanced estradiol delivery system on testosterone and androgen-dependent tissues. I. Dose-response and time-course evaluation.

N. Bodor, J. Simpkins, M. Brewster, 1991, Endocrinology.

Prediction of drug solubility in amphiphilic di-block copolymer micelles: the role of polymer-drug compatibility.

M. Brewster, V. Préat, L. Rouxhet, 2007, Die Pharmazie.

Encapsulation of amphotericin B in poly(ethylene glycol)-block-poly(epsilon-caprolactone-co-trimethylenecarbonate) polymeric micelles.

M. Brewster, G. Vandermeulen, V. Préat, 2006, International journal of pharmaceutics.

Use of a Population Pharmacokinetic Approach for the Clinical Development of a Fixed-Dose Subcutaneous Formulation of Trastuzumab

M. Brewster, B. Lum, F. Hourcade‐Potelleret, 2014, CPT: pharmacometrics & systems pharmacology.

A dihydropyridine conjugate which generates high and sustained levels of the corresponding pyridinium salt in the brain does not exhibit neurotoxicity in cynomolgus monkeys

N. Bodor, M. Brewster, K. S. Estes, 1988, Neuroscience Letters.

Phase behaviour analysis of solid dispersions of loperamide and two structurally related compounds with the polymers PVP-K30 and PVP-VA64.

G. Verreck, J. Peeters, M. Brewster, 2004, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Monoglyceride-based self-assembling copolymers as carriers for poorly water-soluble drugs.

J. Rosenblatt, M. Brewster, V. Préat, 2009, International journal of pharmaceutics.

Collaborative development of 2-hydroxypropyl-β-cyclodextrin for the treatment of Niemann-Pick type C1 disease.

W. Pavan, C. Vite, C. Austin, 2014, Current topics in medicinal chemistry.

Effects of a brain-enhanced chemical delivery system for estradiol on body weight and serum hormones in middle-aged male rats.

N. Bodor, J. Simpkins, M. Brewster, 1988, Endocrine research.

DSC analysis of the anti-HIV agent loviride as a preformulation tool in the development of hot-melt extrudates

G. Verreck, J. Peeters, M. Brewster, 2004 .

High‐speed digital imaging method for ciliary beat frequency measurement

Frederik Maes, F. Maes, M. Brewster, 2005, The Journal of pharmacy and pharmacology.

Brain-Targeted Delivery of Estrogens

N. Bodor, J. Simpkins, M. Brewster, 1990, Reviews in the neurosciences.

Synthesis, characterization and in vitro evaluation of various sulfonamide chemical delivery systems

N. Bodor, M. Brewster, K. Seyda, 1991 .

A survey on IVIVC/IVIVR development in the pharmaceutical industry – Past experience and current perspectives

J. Crison, A. Parr, M. Brewster, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Enhanced Brain Delivery of Amino Acids and Peptides Through the Use of Redox Targeting Systems

N. Bodor, M. Brewster, W. Anderson, 1992 .

Brain-Enhanced Delivery of Anti-Dementia Drugs

N. Bodor, M. Brewster, E. Pop, 1989 .

Reactivity of biologically important reduced pyridines V. Relative importance of electron versus proton loss in ferricyanide-mediated oxidation of dihydronicotinamides

N. Bodor, M. Brewster, Z. Gabányi, 1989 .

Peroxidase-catalyzed S-oxygenation: mechanism of oxygen transfer for lactoperoxidase.

M. Brewster, D. Doerge, N. M. Cooray, 1991, Biochemistry.

Flotation equilibrium of serum low density lipoproteins.

M. Brewster, J. A. Lee, M. D. Morris, 1974, Analytical biochemistry.

Evidence for suppression of serum LH without elevation in serum estradiol or prolactin with a brain-enhanced redox delivery system for estradiol.

N. Bodor, J. Simpkins, M. Brewster, 1988, Life sciences.

Neuroprotective (+) 3S, 4S cannabinoids with modified 5′-side chain

M. Brewster, A. Biegon, E. Pop, 1996 .

Evaluation of an estradiol chemical delivery system (CDS) designed to provide enhanced and sustained hormone levels in the brain

M. Brewster, N. Bodor, K. S. Estes, 1994 .

Use of 2-Hydroxypropyl-β-cyclodextrin as a Solubilizing and Stabilizing Excipient for Protein Drugs

N. Bodor, J. Simpkins, M. Brewster, 1991, Pharmaceutical Research.

Improved Delivery Through Biological Membranes. XLV. Synthesis, Physical-Chemical Evaluation, and Brain Uptake Studies of 2-Chloroethyl Nitrosourea Delivery Systems

N. Bodor, K. Raghavan, M. Brewster, 1992, Pharmaceutical Research.

Applications of chemically-modified cyclodextrins: use of hydroxypropyl-β-cyclodextrin as an enabling excipient for brain targeting, redox-based derivatives of estradiol A review of preclinical and clinical findings

N. Bodor, M. Brewster, T. Loftsson, 2004 .

Application of semiempirical molecular orbital techniques to the study of peroxidase-mediated oxidation of phenols, anilines, sulfides and thiobenzamides

N. Bodor, M. Brewster, D. Doerge, 1991 .

A non-surfactant formulation for alfaxalone based on an amorphous cyclodextrin : activity studies in rats and dogs

N. Bodor, M. Brewster, K. S. Estes, 1990 .

Carbonic anhydrase activators. Part 14. Syntheses of mono and bis pyridinium salt derivatives of 2-amino-5-(2-aminoethyl)- and 2-amino-5-(3-aminopropyl)-1,3,4-thiadiazole and their interaction with isozyme II

C. Supuran, M. Brewster, M. Barboiu, 1996 .

Solvent systems and their selection in pharmaceutics and biopharmaceutics

M. Brewster, P. Augustijns, 2007 .

Targeted delivery of RNA-cleaving DNA enzyme (DNAzyme) to tumor tissue by transferrin-modified, cyclodextrin-based particles

Jianjun Cheng, Mark E. Davis, Annette Bakker, 2004, Cancer biology & therapy.

Development of a non-surfactant formulation for alfaxalone through the use of chemically-modified cyclodextrins.

N. Bodor, M. Brewster, K. S. Estes, 1989, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

An intravenous toxicity study of 2-hydroxypropyl-β-cyclodextrin, a useful drug solubilizer, in rats and monkeys

M. Brewster, N. Bodor, K. S. Estes, 1990 .

Synthesis and Evaluation of a Novel Chemical Delivery System of Zidovudine with Increased Stability at Low pH

N. Bodor, M. Brewster, Zongliang Liu, 2011 .

Substituent effects on the stability of 1,4-dihydropyridines

N. Bodor, M. Brewster, E. Pop, 1995 .

Stability of the 1,3-substituted 1,4-dihydropyridines: Substituent effects on the acid catalyzed hydration and oxidation reactions

N. Bodor, M. Brewster, E. Pop, 1994 .

A Dihydroisoquinoline Targetor-Based Acid Resistant Chemical Delivery System of Azidothymidine (AZT)

N. Bodor, M. Brewster, Zongliang Liu, 1993 .

Reactivity of biologically important reduced pyridines. IV. Effect of substitution on ferricyanide-mediated oxidation rates of various 1,4-dihydropyridines

N. Bodor, M. Brewster, H. Farag, 1989 .

Derivatives of Dexanabinol. II. Salts of Amino Acid Esters Containing Tertiary and Quaternary Heterocyclic Nitrogen with Increased Water-Solubility

Y. Barenholz, M. Brewster, A. Biegon, 1996, Pharmaceutical Research.

Development of aqueous parenteral formulations for carbamazepine through the use of modified cyclodextrins.

N. Bodor, M. Brewster, N Bodor, 1991, Journal of pharmaceutical sciences.

Dimerization of Dexanabinol by Hydrogen Bonding Accounts for Its Hydrophobic Character

M. Brewster, E. Pop, 1997 .

Site-specific, sustained release of drugs to the brain.

N. Bodor, M. Brewster, N Bodor, 1981, Science.

Contributions of Molecular Orbital Techniques to the Study of Dihydropyridines

N. Bodor, M. Brewster, E. Pop, 1994 .

Reactivity of biologically important reduced pyridines

N. Bodor, M. Brewster, J. Kaminski, 1990 .

Theoretical studies on the hydride transfer between 1-methyl-1,4-dihydronicotinamide and its corresponding pyridinium salt

N. Bodor, M. Brewster, J. Kaminski, 1988 .

Carbonic Anhydrase Activators. Part 14. Syntheses of Mono- and Bis( pyridinium)salt Derivatives of 2-Amino-5-(2-aminoethyl)- and 2-Amino-5- (3-aminopropyl)-1,3,4-thiadiazole and Their Interaction with Isozyme II.

C. Supuran, M. Brewster, M. Barboiu, 1996 .

Cyclodextrins as pharmaceutical solubilizers.

Thorsteinn Loftsson, M. Brewster, T. Loftsson, 2007, Advanced drug delivery reviews.

Self-assembly of cyclodextrin complexes: effect of temperature, agitation and media composition on aggregation.

Thorsteinn Loftsson, M. Brewster, T. Loftsson, 2011, International journal of pharmaceutics.

Self-association of cyclodextrins and cyclodextrin complexes.

M. Brewster, M. Másson, T. Loftsson, 2004, Journal of pharmaceutical sciences.

Solubilization and electrochemical stabilization of substituted phenols through the use of 2-hydroxypropyl-β-cyclodextrin

N. Bodor, M. Brewster, C. Kibbey, 1994 .

The use of 2-hydroxypropyl-β-cyclodextrin as a vehicle for intravenous administration of dexamethasone in dogs

N. Bodor, M. Brewster, H. Derendorf, 1990 .

Water Soluble Complexes of a Brain-Targeted Drug Delivery System

N. Bodor, M. Brewster, T. Loftsson, 1988 .

Pharmaceutical applications of cyclodextrins. 1. Drug solubilization and stabilization.

M. Brewster, T. Loftsson, M E Brewster, 1996, Journal of pharmaceutical sciences.

Cyclodextrins as functional excipients: methods to enhance complexation efficiency.

Thorsteinn Loftsson, M. Brewster, T. Loftsson, 2012, Journal of pharmaceutical sciences.

Role of cyclodextrins in improving oral drug delivery

M. Brewster, M. Másson, T. Loftsson, 2004 .

Effects of cyclodextrins on drug delivery through biological membranes.

Thorsteinn Loftsson, M. Brewster, T. Loftsson, 2007, Journal of pharmaceutical sciences.

The potential use of cyclodextrins in parenteral formulations.

N. Bodor, Warren C. Stern, J. Simpkins, 1989, Journal of parenteral science and technology : a publication of the Parenteral Drug Association.

Formulation development for a zidovudine chemical delivery system 2. Towards oral and non-parenteral dosage forms

N. Bodor, M. Brewster, S. Amselem, 1995 .

Preparation, Characterization, and Anesthetic Properties of 2-Hydroxypropyl-β-cyclodextrin Complexes of Pregnanolone and Pregnenolone in Rat and Mouse

N. Bodor, M. Brewster, T. Loftsson, 1995 .

Brain, blood, and cerebrospinal fluid distribution of a zidovudine chemical delivery system in rabbits.

N. Bodor, M. Brewster, W. Anderson, 1991, Journal of pharmaceutical sciences.

An intravenous toxicity study of 2-hydroxypropyf-P-cycle a useful drug so~u~~lizer, in rats and monkeys

M. Brewster, N. Bodor, S. Kerry, 1990 .

An AM1 molecular orbital study of α-D-glucopyranose and β-maltose : evaluation and implications

N. Bodor, M. Dewar, M. Brewster, 1993 .

Stabilization of aspartame by cyclodextrins

N. Bodor, M. Brewster, T. Loftsson, 1991 .

Self-assembly of cyclodextrins: the effect of the guest molecule.

Thorsteinn Loftsson, M. Brewster, T. Loftsson, 2011, International journal of pharmaceutics.

Use of a screening method to determine excipients which optimize the extent and stability of supersaturated drug solutions and application of this system to solid formulation design.

Geert Verreck, G. Verreck, J. Peeters, 2007, International journal of pharmaceutics.

Formulation development for a zidovudine chemical delivery system 1. Parenteral dosage forms

N. Bodor, M. Brewster, S. Amselem, 1995 .

A novel redox system for CNS-directed delivery of estradiol causes sustained LH suppression in castrate rats.

N. Bodor, J. Simpkins, M. Brewster, 1987, Life sciences.

Improved delivery through biological membranes. XXII. Synthesis and distribution of brain-selective estrogen delivery systems

N. Bodor, M. Brewster, J. McCornack, 1987 .

Sustained brain-specific delivery of estradiol causes long-term suppression of luteinizing hormone secretion.

N. Bodor, J. Simpkins, M. Brewster, 1986, Journal of medicinal chemistry.

Problems of delivery of drugs to the brain.

N. Bodor, M. Brewster, 1982, Pharmacology & therapeutics.

Intravenous and oral pharmacokinetic evaluation of a 2-hydroxypropyl-beta-cyclodextrin-based formulation of carbamazepine in the dog: comparison with commercially available tablets and suspensions.

N. Bodor, M. Brewster, R. Sawchuk, 1997, Journal of pharmaceutical sciences.

Improved delivery through biological membranes. XXXL: Solubilization and stabilization of an estradiol chemical delivery system by modified beta-cyclodextrins.

N. Bodor, M. Brewster, H. Derendorf, 1988, Journal of pharmaceutical sciences.

Supersaturating drug delivery systems: fast is not necessarily good enough.

M. Brewster, Marcus E Brewster, Patrick Augustijns, 2012, Journal of pharmaceutical sciences.

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

Patrick Augustijns, M. Brewster, P. Augustijns, 2009, Journal of pharmaceutical sciences.

Comparative interaction of 2-hydroxypropyl-beta-cyclodextrin and sulfobutylether-beta-cyclodextrin with itraconazole: phase-solubility behavior and stabilization of supersaturated drug solutions.

Thorsteinn Loftsson, Geert Verreck, G. Verreck, 2008, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Theoretical study of some heterocyclic amines with applications to the chemistry of 9‐amino‐1,2,3,4‐tetrahydroacridine

N. Bodor, M. Brewster, E. Pop, 1989 .

Redox targeting of LY231617, an antioxidant with potential use in the treatment of brain damage

N. Bodor, M. Brewster, J. Panetta, 1996 .

Salt formation in solid dispersions consisting of polyacrylic acid as a carrier and three basic model compounds resulting in very high glass transition temperatures and constant dissolution properties upon storage.

G. Verreck, J. Peeters, M. Brewster, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying.

G. Verreck, J. Peeters, M. Brewster, 2005, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Characterization of the interaction of 2-hydroxypropyl-beta-cyclodextrin with itraconazole at pH 2, 4, and 7.

J. Peeters, M. Brewster, P. van Remoortere, 2002, Journal of pharmaceutical sciences.

A mucoadhesive, cyclodextrin-based vaginal cream formulation of itraconazole

J. Peeters, M. Brewster, U. Delaet, 2003, AAPS PharmSci.

Clinical study of solid dispersions of itraconazole prepared by hot-stage extrusion.

Geert Verreck, G. Verreck, J. Peeters, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

In vivo methods for drug absorption - comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects.

Talia Flanagan, Clive G. Wilson, Mai Anh Nguyen, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Preclinical and Clinical Studies

G. Verreck, M. Brewster, J. Brouwers, 2015 .

Increased physical stability and improved dissolution properties of itraconazole, a class II drug, by solid dispersions that combine fast- and slow-dissolving polymers.

Geert Verreck, G. Verreck, J. Peeters, 2004, Journal of pharmaceutical sciences.

Improved brain delivery of antiviral agents through the use of redox targeting

N. Bodor, M. Brewster, 1994 .

Enhanced delivery of ganciclovir to the brain through the use of redox targeting

N. Bodor, K. Raghavan, M. Brewster, 1994, Antimicrobial Agents and Chemotherapy.

Improved delivery through biological membranes. XLI. Brain-enhanced delivery of chlorambucil

N. Bodor, M. Brewster, K. S. Estes, 1989 .

Dithionite reduction of pyridinium salts: an AM1 study

N. Bodor, M. Brewster, E. Pop, 1993 .

Preparation and physicochemical characterization of biodegradable nerve guides containing the nerve growth agent sabeluzole.

Joel Rosenblatt, Theo Meert, Jef Adriaensen, 2005, Biomaterials.

Novel self-assembling PEG-p-(CL-co-TMC) polymeric micelles as safe and effective delivery system for paclitaxel.

M. Brewster, V. Préat, F. Danhier, 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Improved Delivery through Biological Membranes. Synthesis and Antiviral Activity of a Series of Ribavirin Chemical Delivery Systems: 2′ and 3′ Derivatives

N. Bodor, M. Brewster, P. Druzgala, 1991 .

Usefulness of a novel Caco-2 cell perfusion system. I. In vitro prediction of the absorption potential of passively diffused compounds.

Bart Willems, M. Brewster, J. Mensch, 2004, Journal of pharmaceutical sciences.

Characterization of physico-chemical properties and pharmaceutical performance of sucrose co-freeze-dried solid nanoparticulate powders of the anti-HIV agent loviride prepared by media milling.

P Augustijns, L. Froyen, M. Brewster, 2007, International journal of pharmaceutics.

Enhanced brain delivery of 2′-fluoro-5-methylarabinosyluracil

N. Bodor, M. Brewster, W. Anderson, 1992 .

Improved Delivery through Biological Membranes. Synthesis, Characterization and Antiviral Activity of a Series of Ribavirin Chemical Delivery Systems: 5 and Carboxamide Derivatives

N. Bodor, M. Brewster, R. Sidwell, 1991 .

Enhanced Delivery ofGanciclovir totheBrain through theUseofRedoxTargeting

M. Brewster, 1994 .

Redox approaches to drug delivery to the central nervous system.

N. Bodor, M. Brewster, 1992, NIDA research monograph.

The Effect of Dihydronicotinate N-Substitution on the Brain-Targeting Efficacy of a Zidovudine Chemical Delivery System

N. Bodor, M. Brewster, P. Druzgala, 1993, Pharmaceutical Research.

Dose-Dependent Brain Delivery of Zidovudine Through the Use of a Zidovudine Chemical Delivery System

N. Bodor, M. Brewster, W. Anderson, 1995, Pharmaceutical Research.

Hydrolytic stability of allylic and phenolic esters of some synthetic cannabinoids: A theoretical (AM1) study

N. Bodor, M. Brewster, E. Pop, 1995 .

A theoretical study of the hydrolysis of some sterically hindered phenolic esters

N. Bodor, M. Brewster, E. Pop, 1992 .

Effect of Sustained Estradiol Release in the Intact Male Rat: Correlation of Estradiol Serum Levels with Actions on Body Weight, Serum Testosterone, and Peripheral Androgen-Dependent Tissues

M. Brewster, W. Anderson, E. Pop, 1997, Physiology & Behavior.

Evidence for the reestablishment of copulatory behavior in castrated male rats with a brain-enhanced estradiol-chemical delivery system

N. Bodor, J. Simpkins, M. Brewster, 1987, Pharmacology Biochemistry and Behavior.

A Redox-Based System that Enhances Delivery of Estradiol to the Brain: Pharmacokinetic Evaluation in the Dog

N. Bodor, M. Brewster, H. Derendorf, 1990, Pharmaceutical Research.

High-Performance Liquid Chromatographic Assay of a Central Nervous System (CNS)-Directed Estradiol Chemical Delivery System and Its Application After Intravenous Administration to Rats

N. Bodor, M. Brewster, H. Derendorf, 1988, Pharmaceutical Research.

The use of chemically modified cyclodextrins in the development of formulations for chemical delivery systems.

M. Brewster, T. Loftsson, 2002, Die Pharmazie.

The effect of supercritical CO2 as a reversible plasticizer and foaming agent on the hot stage extrusion of itraconazole with EC 20 cps

D. Tomasko, G. Verreck, J. Peeters, 2007 .

The effect of pressurized carbon dioxide as a plasticizer and foaming agent on the hot melt extrusion process and extrudate properties of pharmaceutical polymers

D. Tomasko, G. Verreck, J. Peeters, 2006 .

Hot stage extrusion of p-amino salicylic acid with EC using CO2 as a temporary plasticizer.

Jef Adriaensen, Geert Verreck, D. Tomasko, 2006, International journal of pharmaceutics.

The effect of pressurized carbon dioxide as a temporary plasticizer and foaming agent on the hot stage extrusion process and extrudate properties of solid dispersions of itraconazole with PVP-VA 64.

Jef Adriaensen, Geert Verreck, D. Tomasko, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Evaluation of Three Amorphous Drug Delivery Technologies to Improve the Oral Absorption of Flubendazole

G. Verreck, M. Brewster, C. Mackie, 2016, Journal of pharmaceutical sciences.

Physical stability of the amorphous state of loperamide and two fragment molecules in solid dispersions with the polymers PVP-K30 and PVP-VA64.

Geert Verreck, G. Verreck, J. Peeters, 2005, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

The Use of Solubilizing Excipients and Approaches to GenerateToxicology Vehicles for Contemporary Drug Pipelines

M. Brewster, M. Noppe, C. Mackie, 2007 .

Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs.

G. Verreck, J. Peeters, M. Brewster, 2003, International journal of pharmaceutics.

Melt extrusion-based dosage forms: Excipients and processing conditions for pharmaceutical formulations

G. Verreck, M. Brewster, 2004 .

High speed electrospinning for scaled-up production of amorphous solid dispersion of itraconazole.

H. Pataki, Z. Nagy, K. Molnár, 2015, International journal of pharmaceutics.

The use of three different solid dispersion formulations--melt extrusion, film-coated beads, and a glass thermoplastic system--to improve the bioavailability of a novel microsomal triglyceride transfer protein inhibitor.

G. Verreck, J. Peeters, M. Brewster, 2004, Journal of pharmaceutical sciences.

Evaluation of a brain-targeting zidovudine chemical delivery system in dogs

N. Bodor, M. Brewster, H. Derendorf, 1997, Antimicrobial agents and chemotherapy.

A MINDO/3 study of a substituted benzo[b] isoquinolizinium salt ⇆ benzo[b] quinolizine system

N. Bodor, M. Brewster, 1986 .

ANALOGS OF TRYPTOPHAN

N. Bodor, M. Brewster, K. Prokai-Tatrai, 1994 .

Relative reactivity of 1,4‐ and 1,6‐dihydronicotinic acid derivatives to radically mediated oxidation—a theoretical and experimental evaluation

N. Bodor, A. Balaban, M. Brewster, 1995 .

Evaluation of the anticancer action of a permanently charged tamoxifen derivative, tamoxifen methiodide : an MRI study

H. Degani, M. Brewster, A. Biegon, 1997 .

Improved Oral Bioavailability of the Brain-Targeting Estrogen, E2-CDS, through the Use of Carboxymethylethyl-β-Cyclodextrin

N. Bodor, M. Brewster, T. Murakami, 1996 .

Intravenous and Buccal 2-Hydroxypropyl-β-Cyclodextrin Formulations of E2-CDS — Phase I Clinical Trials

N. Bodor, M. Brewster, W. Anderson, 1996 .

Efficacy of a 3-substituted versus 17-substituted chemical delivery system for estradiol brain targeting.

N. Bodor, M. Brewster, P. Druzgala, 1995, Journal of pharmaceutical sciences.

A permanently charged tamoxifen derivative displays anticancer activity and improved tissue selectivity in rodents.

H. Degani, M. Brewster, A. Biegon, 1996, Cancer research.

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters.

Claire Mackie, Geert Verreck, G. Verreck, 2010, International journal of pharmaceutics.

Oral biopharmaceutics tools - time for a new initiative - an introduction to the IMI project OrBiTo.

H Lennernäs, A Lindahl, B Abrahamsson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Prediction of blood-brain barrier penetration of poorly soluble drug candidates using surface activity profiling.

J. Dressman, M. Brewster, J. Mensch, 2010, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Rotational barriers in phenol and sterically congested phenol derivatives, an AM1 study

N. Bodor, M. Brewster, E. Pop, 1994 .

Theoretical aspects of cephalosporin isomerism

N. Bodor, M. Brewster, E. Pop, 2009 .

Delivery of a DNAzyme targeting c-myc to HT29 colon carcinoma cells using a gold nanoparticulate approach.

M. Brewster, M. Janicot, M. Noppe, 2008, Die Pharmazie.

Application of a Brain-Targeting Chemical Delivery System to 9-Amino-1,2,3,4-Tetrahydroacridine

N. Bodor, M. Brewster, K. Prokai-Tatrai, 1990, Pharmaceutical Research.

New Injectable Aqueous Carbamazepine Solution Through Complexing with 2‐Hydroxypropyl‐β‐Cyclodextrin: Tolerability and Pharmacokinetics After Intravenous Injection in Comparison to a Glycofurol‐Based Formulation

W. Löscher, M. Brewster, H. Schulz, 1995, Epilepsia.

Physicochemical properties of the amorphous drug, cast films, and spray dried powders to predict formulation probability of success for solid dispersions: etravirine.

Sheng Qi, Jody Voorspoels, Mike Reading, 2011, Journal of pharmaceutical sciences.

Transport mechanisms of mmePEG750P(CL-co-TMC) polymeric micelles across the intestinal barrier.

M. Brewster, Y. Schneider, V. Préat, 2007, Journal of controlled release : official journal of the Controlled Release Society.

Modified poly(propylene imine) dendrimers as effective transfection agents for catalytic DNA enzymes (DNAzymes)

E. W. Meijer, M. Brewster, M. Janicot, 2006, Journal of drug targeting.

Isomeric interconversions in tamoxifen and related compounds: An AM1 study

N. Bodor, M. Brewster, E. Pop, 1995 .

The use of polymer-based electrospun nanofibers containing amorphous drug dispersions for the delivery of poorly water-soluble pharmaceuticals.

G. Verreck, I. Chun, J. Peeters, 2004, Die Pharmazie.

Nanosuspension for the delivery of a poorly soluble anti-cancer kinase inhibitor.

M. Brewster, V. Préat, F. Danhier, 2014, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Biodegradable Self-Assembling PEG-Copolymer as Vehicle for Poorly Water-Soluble Drugs

J. Rosenblatt, M. Brewster, V. Préat, 2004, Pharmaceutical Research.

Solubilization of itraconazole as a function of cyclodextrin structural space

J. Peeters, M. Brewster, Peter Neeskens, 2007 .

Identification of Phase Separation in Solid Dispersions of Itraconazole and Eudragit® E100 Using Microthermal Analysis

Geert Verreck, G. Verreck, J. Peeters, 2004, Pharmaceutical Research.

Intestinal uptake and biodistribution of novel polymeric micelles after oral administration.

M. Brewster, V. Préat, L. van Beijsterveldt, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Self-assembly of cyclodextrin complexes: aggregation of hydrocortisone/cyclodextrin complexes.

M. Brewster, T. Loftsson, Sergey V. Kurkov, 2011, International journal of pharmaceutics.

Self-assembling PEG-p(CL-co-TMC) copolymers for oral delivery of poorly water-soluble drugs: a case study with risperidone.

X. Langlois, M. Brewster, V. Préat, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Spontaneously self-assembled micelles from poly(ethylene glycol)-b-poly(epsilon-caprolactone-co-trimethylene carbonate) for drug solubilization.

M. Brewster, V. Préat, L. Rouxhet, 2008, Die Pharmazie.

A Redox-Based Chemical Delivery System that Enhances Estradiol Distribution to the Brain: Disposition Studies in the Rat

N. Bodor, M. Brewster, H. Derendorf, 1991, Pharmaceutical Research.

Synthesis of deuterated dexanabinol, a nonpsychotropic cannabinoid with neuroprotective properties

M. Brewster, L. Prokai, S. Rachwał, 1998 .

Clinical pharmacokinetics of escalating i.v. doses of dexanabinol (HU-211), a neuroprotectant agent, in normal volunteers.

M. Brewster, A. Biegon, S. Amselem, 1997, International journal of clinical pharmacology and therapeutics.

ALLYLIC AND PHENOLIC PHOSPHATE ESTERS OF DEXANABINOL

M. Brewster, A. Biegon, E. Pop, 1997 .

Effect of a Chemical Delivery System for Dexamethasone (Dex-CDS) on Peritumoral Edema in an Experimental Brain Tumor Model

M. Brewster, A. Biegon, T. Siegal, 1997, Pharmaceutical Research.

Evidence for prolonged suppression of stress-induced release of adrenocorticotropic hormone and corticosterone with a brain-enhanced dexamethasone-redox delivery system.

N. Bodor, J. Simpkins, M. Brewster, 1989, Neuroendocrinology.

Brain-enhanced delivery of testosterone using a chemical delivery system complexed with 2-hydroxypropyl-beta-cyclodextrin.

N. Bodor, J. Simpkins, M. Brewster, 1988, Drug design and delivery.

Summary Report of PQRI Workshop on Nanomaterial in Drug Products: Current Experience and Management of Potential Risks

Celia N. Cruz, M. Brewster, R. Prud’homme, 2014, The AAPS Journal.

Facile, One-Step Preparation of Trigonellinate Esters

N. Bodor, M. Brewster, E. Shek, 1987 .

Effect of molecular manipulation on the estrogenic activity of a brain-targeting estradiol chemical delivery system.

N. Bodor, M. Brewster, P. Druzgala, 1994, Journal of medicinal chemistry.

Application of PAMPA-models to predict BBB permeability including efflux ratio, plasma protein binding and physicochemical parameters.

Claire Mackie, Geert Verreck, G. Verreck, 2010, International journal of pharmaceutics.

Improved delivery through biological membranes. 32. Synthesis and biological activity of brain-targeted delivery systems for various estradiol derivatives.

N. Bodor, M. Brewster, K. S. Estes, 1988, Journal of medicinal chemistry.

Passive diffusion of polymeric surfactants across lipid bilayers.

M. Brewster, V. Préat, M. Noppe, 2007, Journal of controlled release : official journal of the Controlled Release Society.

A fatality involving U4Euh, a cyclic derivative of phenylpropanolamine.

F. T. Davis, M. Brewster, Frank T. Davis, 1988, Journal of forensic sciences.

Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: dendrimer synthesis, stability and oligonucleotide complexation.

E. W. Meijer, M. Brewster, M. Janicot, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Dendrimeric poly(propylene-imines) as effective delivery agents for DNAzymes: toxicity, in vitro transfection and in vivo delivery.

E. W. Meijer, M. Brewster, M. Janicot, 2006, Journal of controlled release : official journal of the Controlled Release Society.

Physicochemical properties of water and its effect on drug delivery. A commentary.

M. Brewster, T. Loftsson, 2008, International journal of pharmaceutics.

Syntheses and Preliminary Pharmacological Evaluation of Some Chemical Delivery Systems of 2,6‐Diisopropylphenol (Propofol).

N. Bodor, M. Brewster, K. Prokai-Tatrai, 1992 .

A redox system for brain targeted estrogen delivery causes chronic body weight decrease in rats.

N. Bodor, M. Brewster, K. S. Estes, 1988, Life sciences.

Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: An In Depth Analysis.

M. Brewster, C. Mackie, E. Mannaert, 2018, Molecular pharmaceutics.

Clive G. Wilson, A. Peer, H. Lennernäs, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Early pharmaceutical profiling to predict oral drug absorption: current status and unmet needs.

Christel A. S. Bergström, Kung-I Feng, P. Artursson, 2014, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Novel self-assembling PEG-p-(CL-co-TMC) polymeric micelles as safe and effective delivery system for paclitaxel.

M. Brewster, V. Préat, F. Danhier, 2009, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

Nitrogen radical cations as intermediates in enzymatically mediated oxidative deaminations—application of molecular parametric models

N. Bodor, M. Brewster, D. Doerge, 1995 .

AM1-BASED MODEL SYSTEM FOR ESTIMATION OF BRAIN/BLOOD CONCENTRATION RATIOS

N. Bodor, M. Brewster, E. Pop, 1996 .

Usefulness of a novel Caco-2 cell perfusion system II. Characterization of monolayer properties and peptidase activity.

M. Brewster, J. Mensch, M. Noppe, 2009, Die Pharmazie.

Allylic rearrangement of trans‐pinocarveol esters

M. Brewster, S. Rachwał, E. Pop, 1996 .

Anesthetic Activity and Pharmacokinetics of the Neurosteroid Alfaxalone Formulated In 2-Hydroxypropyl-β-Cyclodextrin in the Rat

N. Bodor, M. Brewster, W. Anderson, 1996 .

Qualitative prediction of solubilization of highly hydrophobic drugs in block copolymer micelles.

M. Brewster, V. Préat, M. Dinguizli, 2005, Journal of controlled release : official journal of the Controlled Release Society.

Effect of 2-Hydroxypropyl-β-Cyclodextrin Complexes of the Neurosteroids, Alfaxalone, Pregnanolone and Pregnenolone, on Various Convulsant Stimuli in the Mouse

N. Bodor, M. Brewster, T. Loftsson, 1996 .