E. Akiva

发表

Built-in loops allow versatility in domain–domain interactions: Lessons from self-interacting domains

H. Margalit, E. Akiva, Zohar Itzhaki, 2008, Proceedings of the National Academy of Sciences.

Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics

Scott A. Longwell, C. Sabatti, D. Herschlag, 2020, Science.

Evolutionary conservation of domain-domain interactions

Zohar Itzhaki, Eyal Akiva, Hanah Margalit, 2006, Genome Biology.

Large-Scale Determination of Sequence, Structure, and Function Relationships in Cytosolic Glutathione Transferases across the Biosphere

Richard N. Armstrong, Patricia C. Babbitt, Eyal Akiva, 2014, PLoS biology.

The evolution of human SIRT1 for multi-specificity is enabled by active-site adaptation

E. Akiva, C. Jackson, E. Arbely, 2020, bioRxiv.

Human SIRT1 Multispecificity Is Modulated by Active-Site Vicinity Substitutions during Natural Evolution

E. Akiva, C. Jackson, E. Arbely, 2020, Molecular biology and evolution.

OP-NARE131129 521..530

Conrad C. Huang, Gemma L. Holliday, Shoshana D. Brown, 2013 .

Correction: A Dynamic View of Domain-Motif Interactions

G. Friedlander, H. Margalit, E. Akiva, 2012, PLoS Computational Biology.

[FeFe]-hydrogenase maturation: insights into the role HydE plays in dithiomethylamine biosynthesis.

Eyal Akiva, Gemma L. Holliday, Patricia C Babbitt, 2015, Biochemistry.

A global view of structure–function relationships in the tautomerase superfamily

Eyal Akiva, Gemma L. Holliday, Patricia C Babbitt, 2017, The Journal of Biological Chemistry.

Global landscape of HIV–human protein complexes

John H. Morris, Tom Alber, Eyal Akiva, 2011, Nature.

A Dynamic View of Domain-Motif Interactions

Zohar Itzhaki, Eyal Akiva, Hanah Margalit, 2012, PLoS Comput. Biol..

Evaluating Functional Annotations of Enzymes Using the Gene Ontology

Patricia C. Babbitt, Eyal Akiva, Gemma L. Holliday, 2018, Methods in molecular biology.

Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

Eyal Akiva, Matthew P Jacobson, Suwen Zhao, 2014, eLife.

Evolutionary Reprograming of Protein-Protein Interaction Specificity

P. Babbitt, E. Akiva, 2015, Cell.

Prediction of Mutational Tolerance in HIV-1 Protease and Reverse Transcriptase Using Flexible Backbone Protein Design

Eyal Akiva, Tanja Kortemme, Shane Ó Conchúir, 2012, PLoS Comput. Biol..

Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a "Plug and Play" Domain.

Ursula Pieper, Eyal Akiva, Gemma L. Holliday, 2018, Methods in enzymology.

Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.

E. Akiva, O. Merimsky, R. Sagi-Eisenberg, 2017, Cancer letters.

Parallel molecular mechanisms for enzyme temperature adaptation

P. Babbitt, T. Martínez, D. Herschlag, 2021, Science.

Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily

Patricia C. Babbitt, Eyal Akiva, Janine N. Copp, 2017, Proceedings of the National Academy of Sciences.

Exploring the sequence, function, and evolutionary space of protein superfamilies using sequence similarity networks and phylogenetic reconstructions.

Eyal Akiva, Janine N Copp, Patricia C Babbitt, 2019, Methods in enzymology.

Revealing Unexplored Sequence-Function Space Using Sequence Similarity Networks.

Janine N Copp, Eyal Akiva, Patricia C Babbitt, 2018, Biochemistry.

The Structure–Function Linkage Database

Michael A. Hicks, John H. Morris, Conrad C. Huang, 2013, Nucleic Acids Res..

Public Opinion on the Level of Service and Performance of the Healthcare System in 2009 and in Comparison with Previous Years

E. Akiva, S. Brammli-Greenberg, R. Gross, 2011 .

Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.

Shoshana D. Brown, P. Babbitt, E. Akiva, 2019, Biochemistry.

Mast cells are directly activated by contact with cancer cells by a mechanism involving autocrine formation of adenosine and autocrine/paracrine signaling of the adenosine A3 receptor.

E. Akiva, O. Merimsky, R. Sagi-Eisenberg, 2017, Cancer letters.

Atlas of the Radical SAM Superfamily: Divergent Evolution of Function Using a “Plug & Play” Domain

Gemma L. Holliday, Shoshana D. Brown, A. Sali, 2019 .

Protein Organization with Manifold Exploration and Spectral Clustering

E. Akiva, Shahab Shams, Geoffroy Dubourg-Felonneau, 2021, bioRxiv.

Preferential use of protein domain pairs as interaction mediators: order and transitivity

Zohar Itzhaki, Eyal Akiva, Hanah Margalit, 2010, Bioinform..

Biocuration in the structure–function linkage database: the anatomy of a superfamily

Conrad C. Huang, Thomas E. Ferrin, Elaine C. Meng, 2017, Database : the journal of biological databases and curation.