B. Lewis

发表

Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

C. Denny, O. Delattre, J. Zucman, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance

A. Mangoni, B. Lewis, S. Gray, 2018, Scientific Reports.

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1

C. Denny, M. Klemsz, W. May, 1993, Molecular and cellular biology.

AFM study of the interaction of cytochrome P450 2C9 with phospholipid bilayers.

Nicolas H Voelcker, Matthew J Sykes, N. Voelcker, 2010, Chemistry and physics of lipids.

Generation, validation, and application of a P450 homology model.

J. Miners, B. Lewis, 2013, Current topics in medicinal chemistry.

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development

A. Mangoni, B. Lewis, S. Tommasi, 2016, Molecules.

Identification of the human cytochromes P450 catalysing the rate-limiting pathways of gliclazide elimination.

A. S. Gross, Suharjono, J. Miners, 2007, British journal of clinical pharmacology.

Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance

A. Mangoni, B. Lewis, M. McEvoy, 2017, Scientific Reports.

Morphine Glucuronidation and Glucosidation Represent Complementary Metabolic Pathways That Are Both Catalyzed by UDP-Glucuronosyltransferase 2B7: Kinetic, Inhibition, and Molecular Modeling Studies

J. Miners, B. Lewis, P. Mackenzie, 2014, The Journal of Pharmacology and Experimental Therapeutics.

Arginine analogues incorporating carboxylate bioisosteric functions are micromolar inhibitors of human recombinant DDAH-1.

Pramod C. Nair, A. Mangoni, B. Lewis, 2015, Organic & biomolecular chemistry.

Influence of mutations associated with Gilbert and Crigler–Najjar type II syndromes on the glucuronidation kinetics of bilirubin and other UDP-glucuronosyltransferase 1A substrates

J. Miners, B. Lewis, P. Mackenzie, 2007, Pharmacogenetics and genomics.

Mechanism-Based Inactivation of Human Cytochrome P4502C8 by Drugs in Vitro

J. Miners, B. Lewis, D. Elliot, 2004, Journal of Pharmacology and Experimental Therapeutics.

Mechanism-Based Inactivation of Human Cytochrome P 4502 C 8 by Drugs in Vitro

J. Miners, B. Lewis, D. Elliot, 2004 .

Human dimethylarginine dimethylaminohydrolase 1 inhibition by proton pump inhibitors and the cardiovascular risk marker asymmetric dimethylarginine: in vitro and in vivo significance

A. Mangoni, B. Lewis, M. McEvoy, 2017, Scientific Reports.

The glycosidation of xenobiotics and endogenous compounds: versatility and redundancy in the UDP glycosyltransferase superfamily.

J. Miners, B. Lewis, P. Mackenzie, 2012, Pharmacology & therapeutics.

Purification and properties of a nucleolar endoribonuclease from Novikoff hepatoma.

B. Lewis, H. Busch, A. Prestayko, 1973, Biochimica et biophysica acta.

Endoribonuclease activity associated with nucleolar ribonucleoprotein particles from Novikoff hepatoma.

B. Lewis, H. Busch, A. Prestayko, 1972, Biochimica et biophysica acta.

MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1

A. Mangoni, B. Lewis, D. Hu, 2017, Scientific Reports.

FLI-1 . and is a more powerful transforming gene than activatorencodes a more potent transcriptional The Ewing ' s sarcoma EWS / FLI-1 fusion gene

C. Denny, M. Klemsz, W. May, 2022 .

Heterogeneity of nucleolar U3 ribonucleic acid of the Novikoff hepatoma.

M. Tonato, B. Lewis, H. Busch, 1971, The Journal of biological chemistry.

Application of Homology Modeling to Generate CYP1A1 Mutants with Enhanced Activation of the Cancer Chemotherapeutic Prodrug Dacarbazine

J. Miners, B. Lewis, P. Mackenzie, 2011, Molecular Pharmacology.

Effects of amino acid substitutions at positions 33 and 37 on UDP-glucuronosyltransferase 1A9 (UGT1A9) activity and substrate selectivity.

A. Rowland, J. Miners, B. Lewis, 2012, Biochemical pharmacology.

Impaired dacarbazine activation and 7-ethoxyresorufin deethylation in vitro by polymorphic variants of CYP1A1 and CYP1A2: implications for cancer therapy

J. Miners, B. Lewis, Porntipa Korprasertthaworn, 2016, Pharmacogenetics and genomics.

An evaluation of potential mechanism-based inactivation of human drug metabolizing cytochromes P450 by monoamine oxidase inhibitors, including isoniazid.

J. Miners, B. Lewis, A. Somogyi, 2006, British journal of clinical pharmacology.

Omental Infarction Mimicking Cholecystitis

B. Lewis, D. Watson, David J Smolilo, 2015, Case reports in surgery.

Warfarin resistance associated with genetic polymorphism of VKORC1: linking clinical response to molecular mechanism using computational modeling

John O. Miners, Pramod C. Nair, Matthew P. Doogue, 2016, Pharmacogenetics and genomics.

Electrochemical characterisation of the human cytochrome P450 CYP2C9.

J. Miners, B. Lewis, D. Elliot, 2005, Biochemical pharmacology.

Drug and Chemical Glucosidation by Control Supersomes and Membranes from Spodoptera frugiperda (Sf) 9 Cells: Implications for the Apparent Glucuronidation of Xenobiotics by UDP-glucuronosyltransferase 1A5

J. Miners, B. Lewis, P. Mackenzie, 2018, Drug Metabolism and Disposition.

Critical Roles of Residues 36 and 40 in the Phenol and Tertiary Amine Aglycone Substrate Selectivities of UDP-Glucuronosyltransferases 1A3 and 1A4

J. Miners, B. Lewis, P. Mackenzie, 2007, Molecular Pharmacology.

MiR-193b regulates breast cancer cell migration and vasculogenic mimicry by targeting dimethylarginine dimethylaminohydrolase 1

A. Mangoni, B. Lewis, D. Hu, 2017, Scientific Reports.

Identification of Residues That Confer Sugar Selectivity to UDP-Glycosyltransferase 3A (UGT3A) Enzymes*

J. Miners, B. Lewis, P. Mackenzie, 2012, The Journal of Biological Chemistry.

Comparative homology modeling of human cytochrome P4501A1 (CYP1A1) and confirmation of residues involved in 7-ethoxyresorufin O-deethylation by site-directed mutagenesis and enzyme kinetic analysis.

J. Miners, B. Lewis, P. Mackenzie, 2007, Archives of biochemistry and biophysics.

Creation of a yeast artificial chromosome fragmentation vector based on lysine-2.

C. Denny, B. Lewis, N. Shah, 1992, Genetic analysis, techniques and applications.

Homodimerization of UDP-glucuronosyltransferase 2B7 (UGT2B7) and identification of a putative dimerization domain by protein homology modeling.

J. Miners, B. Lewis, P. Mackenzie, 2011, Biochemical pharmacology.

Amino terminal domains of human UDP-glucuronosyltransferases (UGT) 2B7 and 2B15 associated with substrate selectivity and autoactivation.

J. Miners, B. Lewis, P. Mackenzie, 2007, Biochemical pharmacology.

Refractometric sensing of Li salt with visible-light Si3N4 microdisk resonators

B. Lewis, C. Doolin, P. Doolin, 2014, 1412.7167.

Biodistribution and PET Imaging of pharmacokinetics of manganese in mice using Manganese-52

B. Lewis, T. Aweda, S. Lapi, 2017, PloS one.