Y. Shai

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Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography.

Y. Shai, M. Flashner, I. Chaiken, 1987, Biochemistry.

HIV-1 gp41 transmembrane domain interacts with the fusion peptide: implication in lipid mixing and inhibition of virus-cell fusion.

Y. Shai, R. Blumenthal, Mathias Viard, 2012, Biochemistry.

Specificity in Transmembrane Helix-Helix Interactions Mediated by Aromatic Residues*

Doron Gerber, Neta Sal-Man, Y. Shai, 2007, Journal of Biological Chemistry.

A combined pulse EPR and Monte Carlo simulation study provides molecular insight on peptide-membrane interactions.

Nir Ben-Tal, Yana Gofman, Daniella Goldfarb, 2009, The journal of physical chemistry. B.

Membrane integration of a mitochondrial signal-anchored protein does not require additional proteinaceous factors.

Nir Ben-Tal, Yana Gofman, Doron Rapaport, 2012, The Biochemical journal.

Patterning gradient properties from sub-micrometers to millimeters by magnetolithography.

R. Naaman, Y. Shai, Tatikonda Anand Kumar, 2010, Nano letters.

Ultrashort antibacterial and antifungal lipopeptides

Y. Shai, D. Avrahami, A. Makovitzki, 2006, Proceedings of the National Academy of Sciences.

A class of highly potent antibacterial peptides derived from pardaxin, a pore-forming peptide isolated from Moses sole fish Pardachirus marmoratus.

Y. Shai, Z. Oren, 1996, European journal of biochemistry.

Ranacyclins, a new family of short cyclic antimicrobial peptides: biological function, mode of action, and parameters involved in target specificity.

David Andreu, Niv Papo, Y. Shai, 2003, Biochemistry.

Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by alpha-helical antimicrobial and cell non-selective membrane-lytic peptides.

Y. Shai, Y Shai, 1999, Biochimica et biophysica acta.

Mode of action of membrane active antimicrobial peptides.

Y. Shai, Yechiel Shai, 2002, Biopolymers.

New lytic peptides based on the D,L-amphipathic helix motif preferentially kill tumor cells compared to normal cells.

Niv Papo, Y. Shai, N. Papo, 2003, Biochemistry.

A Novel Lytic Peptide Composed of dl-Amino Acids Selectively Kills Cancer Cells in Culture and in Mice*

Niv Papo, Y. Shai, N. Papo, 2003, Journal of Biological Chemistry.

Inhibition of tumor growth and elimination of multiple metastases in human prostate and breast xenografts by systemic inoculation of a host defense-like lytic peptide.

Vyacheslav Kalchenko, Hadassa Degani, Niv Papo, 2006, Cancer research.

Lipopolysaccharide (Endotoxin)-host defense antibacterial peptides interactions: role in bacterial resistance and prevention of sepsis.

Y. Shai, Yosef Rosenfeld, 2006, Biochimica et biophysica acta.

A Molecular Mechanism for Lipopolysaccharide Protection of Gram-negative Bacteria from Antimicrobial Peptides*

Niv Papo, Y. Shai, N. Papo, 2005, Journal of Biological Chemistry.

The HIV gp41 pocket binding domain enables C-terminal heptad repeat transition from mediating membrane fusion to immune modulation.

Y. Shai, Benjamin Dubreuil, Yoel A. Klug, 2016, The Biochemical journal.

Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes.

Y. Shai, A. Mor, D. Rapaport, 1992, Biochemistry.

Insertion and Organization within Membranes of the δ-Endotoxin Pore-forming Domain, Helix 4-Loop-Helix 5, and Inhibition of Its Activity by a Mutant Helix 4 Peptide*

Y. Shai, D. Gerber, Doron Gerber, 2000, The Journal of Biological Chemistry.

The structure and organization within the membrane of the helices composing the pore-forming domain of Bacillus thuringiensis delta-endotoxin are consistent with an "umbrella-like" structure of the pore.

Y. Shai, M. Sansom, E. Gazit, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Can we predict biological activity of antimicrobial peptides from their interactions with model phospholipid membranes?

Niv Papo, Y. Shai, N. Papo, 2003, Peptides.

Antimicrobial Host Defensins – Specific Antibiotic Activities and Innate Defense Modulation

Y. Shai, H. Sahl, M. Wilmes, 2012, Front. Immun..

Lipopolysaccharide, a Key Molecule Involved in the Synergism between Temporins in Inhibiting Bacterial Growth and in Endotoxin Neutralization*

Maria Luisa Mangoni, Richard M. Epand, Y. Shai, 2008, Journal of Biological Chemistry.

Mechanistic and Functional Studies of the Interaction of a Proline-rich Antimicrobial Peptide with Mammalian Cells*

Y. Shai, N. Papo, M. Zanetti, 2006, Journal of Biological Chemistry.

Sustained Release of Antibacterial Lipopeptides from Biodegradable Polymers against Oral Pathogens

Y. Houri-Haddad, Y. Shai, S. Beyth, 2016, PloS one.

Biohybrid Polymer-Antimicrobial Peptide Medium against Enterococcus faecalis

Y. Shai, A. Domb, N. Beyth, 2014, PloS one.

A New Group of Antifungal and Antibacterial Lipopeptides Derived from Non-membrane Active Peptides Conjugated to Palmitic Acid*

Y. Shai, D. Avrahami, 2004, Journal of Biological Chemistry.

Channel formation properties of synthetic pardaxin and analogues.

Y. Shai, D. Bach, A. Yanovsky, 1990, The Journal of biological chemistry.

Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles.

Y. Shai, E. Gazit, H. G. Boman, 1995, Biochemistry.

Mode of action of linear amphipathic α-helical antimicrobial peptides

Y. Shai, Z. Oren, Ziv Oren, 1998 .

From “carpet” mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides

Y. Shai, Z. Oren, 2001, Peptides.

Effect of multiple aliphatic amino acids substitutions on the structure, function, and mode of action of diastereomeric membrane active peptides.

Y. Shai, D. Avrahami, Z. Oren, 2001, Biochemistry.

The effect of cyclization of magainin 2 and melittin analogues on structure, function, and model membrane interactions: implication to their mode of action.

T. Unger, Y. Shai, Z. Oren, 2001, Biochemistry.

The Consequence of Sequence Alteration of an Amphipathic α-Helical Antimicrobial Peptide and Its Diastereomers*

Y. Shai, H. Sahl, N. Papo, 2002, The Journal of Biological Chemistry.

Opposing Effects of PhoPQ and PmrAB on the Properties of Salmonella enterica serovar Typhimurium: Implications on Resistance to Antimicrobial Peptides

Y. Shai, H. Sahl, E. Shimoni, 2021, Biochemistry.

Defensive remodeling: How bacterial surface properties and biofilm formation promote resistance to antimicrobial peptides.

Y. Shai, Tal Shprung, Reut Nuri, 2015, Biochimica et biophysica acta.

Structure and orientation of the mammalian antibacterial peptide cecropin P1 within phospholipid membranes.

Y. Shai, M. Sansom, E. Gazit, 1996, Journal of molecular biology.

Bestowing antifungal and antibacterial activities by lipophilic acid conjugation to D,L-amino acid-containing antimicrobial peptides: a plausible mode of action.

Y. Shai, D. Avrahami, 2003, Biochemistry.

Tracking of Intracellular Assembly of Hantavirus Glycoprotein Complex by a Toolbox of Fluorescence Microscopy Techniques

Y. Shai, A. Herrmann, S. Chiantia, 2020 .

Intramolecular interactions within the human immunodeficiency virus-1 gp41 loop region and their involvement in lipid merging.

Y. Shai, Elisa Merklinger, A. Ashkenazi, 2012, Biochemistry.

Viral envelope protein folding and membrane hemifusion are enhanced by the conserved loop region of HIV‐1 gp41

Y. Shai, R. Blumenthal, Mathias Viard, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

On the interaction between gp41 and membranes: the immunodominant loop stabilizes gp41 helical hairpin conformation.

S. Peisajovich, Y. Shai, R. Epand, 2003, Journal of molecular biology.

Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents.

Y. Shai, H. Sahl, R. Liskamp, 2012, Journal of medicinal chemistry.

ATR-FTIR studies in pore forming and membrane induced fusion peptides.

Y. Shai, 2013, Biochimica et biophysica acta.

Kinetics of interaction of HIV fusion protein (gp41) with lipid membranes studied by real-time AFM imaging.

Sidney R. Cohen, Y. Shai, Y. Fridmann-Sirkis, 2010, Ultramicroscopy.

Endotoxin (Lipopolysaccharide) Neutralization by Innate Immunity Host-Defense Peptides

Y. Shai, N. Papo, Yosef Rosenfeld, 2006, Journal of Biological Chemistry.

and against Bacterial and Fungal Pathogens Induce Systemic Plant Defense Responses Synthetic Ultrashort Cationic Lipopeptides

Y. Shai, A. Makovitzki, I. Chet, 2009 .

Temporins A and B Stimulate Migration of HaCaT Keratinocytes and Kill Intracellular Staphylococcus aureus

Y. Shai, M. Mangoni, A. Di Grazia, 2014, Antimicrobial Agents and Chemotherapy.

Topology of the trans-membrane peptide WALP23 in model membranes under negative mismatch conditions.

M. Eisenstein, Y. Shai, H. Zimmermann, 2013, The journal of physical chemistry. B.

Effect of drastic sequence alteration and D-amino acid incorporation on the membrane binding behavior of lytic peptides.

Niv Papo, Y. Shai, N. Papo, 2004, Biochemistry.

Utilizing ESEEM spectroscopy to locate the position of specific regions of membrane-active peptides within model membranes.

Y. Shai, N. Papo, H. Zimmermann, 2006, Biophysical journal.

Viral Fusion Peptides

Y. Shai, A. Ashkenazi, 2013 .

Direct evidence that the N-terminal heptad repeat of Sendai virus fusion protein participates in membrane fusion.

Y. Shai, J. K. Ghosh, 1999, Journal of molecular biology.

Lipid clustering by three homologous arginine-rich antimicrobial peptides is insensitive to amino acid arrangement and induced secondary structure.

Guangshun Wang, Y. Shai, R. Epand, 2010, Biochimica et biophysica acta.

The polar region consecutive to the HIV fusion peptide participates in membrane fusion.

S. Peisajovich, Y. Shai, R. Epand, 2000, Biochemistry.

Sendai virus internal fusion peptide: structural and functional characterization and a plausible mode of viral entry inhibition.

S. Peisajovich, Y. Shai, J. K. Ghosh, 2000, Biochemistry.

Participation of two fusion peptides in measles virus-induced membrane fusion: emerging similarity with other paramyxoviruses.

Y. Shai, O. Samuel, 2001, Biochemistry.

The HTLV-1 gp21 fusion peptide inhibits antigen specific T-cell activation in-vitro and in mice

V. Rotter, Y. Shai, D. Harari, 2018, PLoS pathogens.

Site-Specific Isopeptide Bond Formation: A Powerful Tool for the Generation of Potent and Nontoxic Antimicrobial Peptides

Y. Shai, Elad Stolovicki, N. A. Wani, 2022, Journal of medicinal chemistry.

Spectrum of antimicrobial activity and assembly of dermaseptin-b and its precursor form in phospholipid membranes.

Y. Shai, A. Mor, P. Nicolas, 1994, Biochemistry.

Conjugation of a magainin analogue with lipophilic acids controls hydrophobicity, solution assembly, and cell selectivity.

Y. Shai, D. Avrahami, 2002, Biochemistry.

Impairment of innate immune killing mechanisms by bacteriostatic antibiotics

V. Nizet, Y. Shai, George Y. Liu, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Antimicrobial lipopolypeptides composed of palmitoyl Di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action.

Y. Shai, A. Makovitzki, J. Baram, 2008, Biochemistry.

D-Alanylation of Lipoteichoic Acids Confers Resistance to Cationic Peptides in Group B Streptococcus by Increasing the Cell Wall Density

Y. Shai, E. Shimoni, P. Trieu-Cuot, 2012, PLoS pathogens.

In vitro activity and mode of action of diastereomeric antimicrobial peptides against bacterial clinical isolates.

Y. Shai, H. Sahl, N. Papo, 2004, The Journal of antimicrobial chemotherapy.

The Topology, in Model Membranes, of the Core Peptide Derived from the T‐Cell Receptor Transmembrane Domain

M. Eisenstein, Y. Shai, D. Goldfarb, 2013, Chembiochem : a European journal of chemical biology.

like Lytic Peptides − pH-Dependent Host Defense Intratumor and Systemic Inoculation of Histidine-Rich and Suppression of Human Solid Tumor Growth in Mice

Y. Shai, A. Makovitzki, A. Fink, 2009 .

Single-particle tracking reveals switching of the HIV fusion peptide between two diffusive modes in membranes.

Y. Shai, G. Haran, M. Ott, 2013, The journal of physical chemistry. B.

Fractal properties of cell surface structures: A view from AFM.

Y. Shai, A. Bitler, R. Dover, 2018, Seminars in cell & developmental biology.

Characterization of the interacting domain of the HIV-1 fusion peptide with the transmembrane domain of the T-cell receptor.

M. Pevsner-Fischer, I. Cohen, Y. Shai, 2008, Biochemistry.

Conformational stability and membrane interaction of the full-length ectodomain of HIV-1 gp41: implication for mode of action.

Y. Shai, R. Epand, R. Epand, 2009, Biochemistry.

Characterization of the HIV N-terminal Fusion Peptide-containing Region in Context of Key gp41 Fusion Conformations*

Y. Shai, Yael Wexler-Cohen, K. Sackett, 2006, Journal of Biological Chemistry.

Investigation of model membrane disruption mechanism by melittin using pulse electron paramagnetic resonance spectroscopy and cryogenic transmission electron microscopy.

Y. Shai, H. Zimmermann, S. Wolf, 2012, The journal of physical chemistry. B.

TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge

T. Salame, Eyal David, Steffen Jung, 2019, The Journal of Immunology.

A MOLECULAR MECHANISM FOR LPS PROTECTION OF GRAM-NEGATIVE BACTERIA FROM ANTIMICROBIAL PEPTIDES

Y. Shai, N. Papo, 2004 .

Kinetics and thermodynamics of the microgene polymerization reaction.

Y. Shai, 2009, Biophysical journal.

The GBS PI-2a Pilus Is Required for Virulence in Mice Neonates

Y. Shai, S. Dramsi, G. Teti, 2011, PloS one.

Insights into the mechanism of HIV-1 envelope induced membrane fusion as revealed by its inhibitory peptides

Y. Shai, A. Ashkenazi, 2011, European Biophysics Journal.

Hairpin folding of HIV gp41 abrogates lipid mixing function at physiologic pH and inhibits lipid mixing by exposed gp41 constructs.

Y. Shai, D. Weliky, Matthew J. Nethercott, 2009, Biochemistry.

Fusion Peptides Derived from the HIV Type 1 Glycoprotein 41 Associate within Phospholipid Membranes and Inhibit Cell-Cell Fusion

Y. Shai, R. Blumenthal, P. Jones, 1997, The Journal of Biological Chemistry.

A Structurally Altered d,l-Amino Acid TCRα Transmembrane Peptide Interacts with the TCRα and Inhibits T-Cell Activation in Vitro and in an Animal Model†

I. Cohen, F. Quintana, Y. Shai, 2007 .

The Identification of a Minimal Dimerization Motif QXXS That Enables Homo- and Hetero-association of Transmembrane Helices in Vivo*

Y. Shai, D. Gerber, N. Sal-Man, 2005, Journal of Biological Chemistry.

Arginine mutations within a transmembrane domain of Tar, an Escherichia coli aspartate receptor, can drive homodimer dissociation and heterodimer association in vivo.

Y. Shai, N. Sal-Man, Neta Sal-Man, 2005, The Biochemical journal.

Broad spectrum antibiotic activity of the skin-PYY.

Y. Shai, A. Mor, P. Nicolas, 1996, FEBS letters.

Interaction of fluorescently labeled pardaxin and its analogues with lipid bilayers.

Y. Shai, D. Rapaport, D. Rapaport, 1991, The Journal of biological chemistry.

Conolysin-Mt: a conus peptide that disrupts cellular membranes.

Y. Shai, J. Biggs, B. Olivera, 2007, Biochemistry.

A Synergism between Temporins toward Gram-negative Bacteria Overcomes Resistance Imposed by the Lipopolysaccharide Protective Layer*

Y. Shai, D. Barra, M. Simmaco, 2006, Journal of Biological Chemistry.

d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

A. Pini, Y. Shai, M. Mangoni, 2015, Amino Acids.

Membrane-induced conformational change during the activation of HIV-1 gp41.

S. Peisajovich, Y. Shai, R. Blumenthal, 2000, Journal of molecular biology.

Antimicrobial Peptides against Multidrug-Resistant Pseudomonas aeruginosa Biofilm from Cystic Fibrosis Patients

Y. Shai, Gal Kapach, O. Efrati, 2022, Journal of medicinal chemistry.

Switching Bond: Generation of New Antimicrobial Peptides via the Incorporation of an Intramolecular Isopeptide Bond

Y. Shai, Elad Stolovicki, Gal Kapach, 2021, ACS infectious diseases.

CAMP-Membrane Interactions Using Fluorescence Spectroscopy

Y. Shai, Ron Saar Dover, 2013 .

Peptide interaction with and insertion into membranes.

Y. Shai, A. Ashkenazi, Ron Saar Dover, 2013, Methods in molecular biology.

Temporins and their synergism against Gram-negative bacteria and in lipopolysaccharide detoxification.

Y. Shai, M. Mangoni, 2009, Biochimica et biophysica acta.

Parameters involved in antimicrobial and endotoxin detoxification activities of antimicrobial peptides.

Y. Shai, H. Sahl, Yosef Rosenfeld, 2008, Biochemistry.

Ion release from vesicles induced by pardaxin and its analogues

Y. Shai, I. Miller, L. Doll, 1993 .

Aggregation and organization of pardaxin in phospholipid membranes. A fluorescence energy transfer study.

Y. Shai, D. Rapaport, 1992, The Journal of biological chemistry.

pH-dependent pore formation properties of pardaxin analogues.

Y. Shai, Y. Hadari, A. Finkels, 1991, The Journal of biological chemistry.

Artificial beta-defensin based on a minimal defensin template.

Y. Shai, H. Sahl, A. Tossi, 2009, The Biochemical journal.

Target for Prevention of Sepsis Domains Is Essential for Activation and Is a Assembly of the TLR2/6 Transmembrane

Y. Shai, E. Reuven, Christopher J. Arnusch, 2013 .

2D-NMR and ATR-FTIR study of the structure of a cell-selective diastereomer of melittin and its orientation in phospholipids.

J. Anglister, Y. Shai, M. Sharon, 1999, Biochemistry.

Androctonin, a hydrophilic disulphide-bridged non-haemolytic anti-microbial peptide: a plausible mode of action.

Y. Shai, J. Hoffmann, C. Hétru, 2000, The Biochemical journal.

Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation.

Y. Shai, Y. Kliger, 2000, Journal of molecular biology.

Assembly of the TLR2/6 Transmembrane Domains Is Essential for Activation and Is a Target for Prevention of Sepsis

Y. Shai, E. Reuven, Christopher J. Arnusch, 2013, The Journal of Immunology.

From innate immunity to de-novo designed antimicrobial peptides.

Y. Shai, 2002, Current pharmaceutical design.

18F-labeled insulin: a prosthetic group methodology for incorporation of a positron emitter into peptides and proteins.

K. Jacobson, Y. Shai, J. Roth, 1989, Biochemistry.

Reversible surface aggregation in pore formation by pardaxin.

Y. Shai, S. Nir, D. Rapaport, 1996, Biophysical journal.

Capacities of pardaxin analogues to induce fusion and leakage of negatively charged phospholipid vesicles are not necessarily correlated.

Y. Shai, S. Nir, D. Rapaport, 1994, Biochemistry.

Secondary structure and membrane localization of synthetic segments and a truncated form of the IsK (minK) protein.

Y. Shai, I. Ben-Efraim, J. Strahilevitz, 1994, Biochemistry.

pH- and ionic strength-dependent fusion of phospholipid vesicles induced by pardaxin analogues or by mixtures of charge-reversed peptides.

Y. Shai, D. Rapaport, Y. Pouny, 1993, Biochemistry.

Structural and Mechanistic Evidence for Calcium Interacting Sites in the HIV Transmembrane Protein gp41 Involved in Membrane Fusion

Y. Shai, A. Ramamoorthy, R. Schwarzer, 2022, Biochemistry.

Sphingopeptides: dihydrosphingosine‐based fusion inhibitors against wild‐type and enfuvirtide‐resistant HIV‐1

Y. Shai, R. Blumenthal, Mathias Viard, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Virus‐cell and cell‐cell fusion mediated by the HIV‐1 envelope glycoprotein is inhibited by short gp41 N‐terminal membrane‐anchored peptides lacking the critical pocket domain

Y. Shai, R. Blumenthal, Mathias Viard, 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Demonstrating the C‐terminal boundary of the HIV 1 fusion conformation in a dynamic ongoing fusion process and implication for fusion inhibition

Y. Shai, Yael Wexler-Cohen, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The HIV fusion peptide adopts intermolecular parallel beta-sheet structure in membranes when stabilized by the adjacent N-terminal heptad repeat: a 13C FTIR study.

Y. Shai, K. Sackett, Kelly Sackett, 2005, Journal of molecular biology.

The stability of the intact envelope glycoproteins is a major determinant of sensitivity of HIV/SIV to peptidic fusion inhibitors.

S. A. Gallo, Y. Shai, R. Blumenthal, 2004, Journal of molecular biology.

The C- and the N-terminal Regions of Glycoprotein 41 Ectodomain Fuse Membranes Enriched and Not Enriched with Cholesterol, Respectively*

S. A. Gallo, Y. Shai, R. Blumenthal, 2004, Journal of Biological Chemistry.

How structure correlates to function for membrane associated HIV-1 gp41 constructs corresponding to the N-terminal half of the ectodomain.

Y. Shai, K. Sackett, Kelly Sackett, 2003, Journal of molecular biology.

Fatty acids can substitute the HIV fusion peptide in lipid merging and fusion: an analogy between viral and palmitoylated eukaryotic fusion proteins.

Y. Shai, N. Lev, 2007, Journal of molecular biology.

Inhibition of HIV-1 Envelope Glycoprotein-mediated Cell Fusion by a DL-Amino Acid-containing Fusion Peptide

Y. Shai, R. Blumenthal, D. Gerber, 2004, Journal of Biological Chemistry.

Bacillus thuringiensis cytolytic toxin associates specifically with its synthetic helices A and C in the membrane bound state. Implications for the assembly of oligomeric transmembrane pores.

Y. Shai, E. Gazit, D. Ellar, 1997, Biochemistry.

The assembly and organization of the alpha 5 and alpha 7 helices from the pore-forming domain of Bacillus thuringiensis delta-endotoxin. Relevance to a functional model.

Y. Shai, E. Gazit, 1995, The Journal of biological chemistry.

Heat Shock Protein 90 Facilitates Latent HIV Reactivation through Maintaining the Function of Positive Transcriptional Elongation Factor b (p-TEFb) under Proteasome Inhibition*

Y. Shai, Shuwen Liu, Ruxia Ren, 2016, The Journal of Biological Chemistry.

Liposomes in identification and characterization of viral fusogenic peptides.

S. Peisajovich, Y. Shai, 2003, Methods in enzymology.

Selective cytotoxicity of dermaseptins

Y. Shai, A. Mor, J. K. Ghosh, 1999 .

A highly conserved sequence associated with the HIV gp41 loop region is an immunomodulator of antigen-specific T cells in mice.

A. Ben-nun, Y. Shai, A. Ashkenazi, 2013, Blood.

is an immunomodulator of antigen-specific T cells in mice A highly conserved sequence associated with the HIV gp41 loop region

A. Ben-nun, Y. Shai, A. Ashkenazi, 2013 .

Multiparametric AFM reveals turgor-responsive net-like peptidoglycan architecture in live streptococci

Y. Shai, E. Shimoni, P. Trieu-Cuot, 2015, Nature Communications.

The HIV-1 gp41 N-terminal heptad repeat plays an essential role in membrane fusion.

Y. Shai, K. Sackett, Kelly Sackett, 2002, Biochemistry.

Response to “Interaction between HIV gp41 fusion peptide and T cell receptor: putting the puzzle pieces back together”

I. Cohen, F. Quintana, Y. Shai, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Oncolytic designer host defense peptide suppresses growth of human liposarcoma

M. V. von Duering, F. Jacobsen, Y. Shai, 2011, International journal of cancer.

Effect of nonpolar substitutions of the conserved Phe11 in the fusion peptide of HIV-1 gp41 on its function, structure, and organization in membranes.

R. Doms, Y. Shai, M. Pritsker, 1999, Biochemistry.

A leucine zipper-like sequence from the cytoplasmic tail of the HIV-1 envelope glycoprotein binds and perturbs lipid bilayers.

Y. Shai, Y. Kliger, 1997, Biochemistry.

Interaction of fluorescently labeled analogues of the amino-terminal fusion peptide of Sendai virus with phospholipid membranes.

Y. Shai, D. Rapaport, 1994, The Journal of biological chemistry.

The HIV-1 Envelope Transmembrane Domain Binds TLR2 through a Distinct Dimerization Motif and Inhibits TLR2-Mediated Responses

Y. Shai, E. Reuven, A. Futerman, 2014, PLoS pathogens.

SIV gp41 binds to membranes both in the monomeric and trimeric states: consequences for the neuropathology and inhibition of HIV infection.

S. Peisajovich, Y. Shai, 2001, Journal of molecular biology.

Regulation of innate immune responses by transmembrane interactions: lessons from the TLR family.

Y. Shai, E. Reuven, A. Fink, 2014, Biochimica et biophysica acta.

Structural adaptation of the glycophorin A transmembrane homodimer to D-amino acid modifications.

Y. Shai, D. Gerber, Neta Sal-Man, 2004, Journal of molecular biology.

Chirality-independent protein-protein recognition between transmembrane domains in vivo.

Y. Shai, D. Gerber, Doron Gerber, 2002, Journal of molecular biology.

Mode of Action of an Antiviral Peptide from HIV-1

S. A. Gallo, S. Peisajovich, Y. Shai, 2001, The Journal of Biological Chemistry.

Paramyxovirus F1 protein has two fusion peptides: implications for the mechanism of membrane fusion1

S. Peisajovich, Y. Shai, Orit Samuel, 2000, Journal of Molecular Biology.

Membrane-induced step in the activation of Sendai virus fusion protein.

Y. Shai, I. Ben-Efraim, Y. Kliger, 1999, Journal of molecular biology.

Structure-Function Study of a Heptad Repeat Positioned Near the Transmembrane Domain of Sendai Virus Fusion Protein Which Blocks Virus-Cell Fusion*

S. Peisajovich, Y. Shai, J. K. Ghosh, 1998, The Journal of Biological Chemistry.

A synthetic all D-amino acid peptide corresponding to the N-terminal sequence of HIV-1 gp41 recognizes the wild-type fusion peptide in the membrane and inhibits HIV-1 envelope glycoprotein-mediated cell fusion.

Y. Shai, R. Blumenthal, M. Pritsker, 1998, Proceedings of the National Academy of Sciences of the United States of America.

The structure and organization of synthetic putative membranous segments of ROMK1 channel in phospholipid membranes.

Y. Shai, I. Ben-Efraim, 1997, Biophysical journal.

Secondary structure, membrane localization, and coassembly within phospholipid membranes of synthetic segments derived from the N‐ and C‐termini regions of the ROMK1 K+ channel

Y. Shai, I. Ben-Efraim, 1996, Protein science : a publication of the Protein Society.

Synthetic peptides corresponding to the four P regions of Electrophorus electricus Na+ channel: interaction with and organization in model phospholipid membranes.

Y. Shai, Y. Pouny, 1995, Biochemistry.

The Assembly and Organization of the α5 and α7 Helices from the Pore-forming Domain of Bacillusthuringiensis δ-Endotoxin

Y. Shai, E. Gazit, 1995, The Journal of Biological Chemistry.

Mechanisms for the modulation of membrane bilayer properties by amphipathic helical peptides

Y. Shai, R. Epand, J. Segrest, 1995, Biopolymers.

Mode of action of the antibacterial cecropin B2: a spectrofluorometric study.

Y. Shai, E. Gazit, P. Brey, 1994, Biochemistry.

Synthetic S-2 and H-5 segments of the Shaker K+ channel: secondary structure, membrane interaction, and assembly within phospholipid membranes.

Y. Shai, H. Peled, 1994, Biochemistry.

Structural characterization, membrane interaction, and specific assembly within phospholipid membranes of hydrophobic segments from Bacillus thuringiensis var. israelensis cytolytic toxin.

Y. Shai, E. Gazit, 1993, Biochemistry.

Membrane interaction and self-assembly within phospholipid membranes of synthetic segments corresponding to the H-5 region of the shaker K+ channel.

Y. Shai, H. Peled, 1993, Biochemistry.

Spectroscopic and functional characterization of the putative transmembrane segment of the minK potassium channel.

Y. Shai, I. Ben-Efraim, D. Bach, 1993, Biochemistry.

Membrane interactions of the sodium channel S4 segment and its fluorescently-labeled analogues.

Y. Shai, E. Gazit, D. Rapaport, 1992, Biochemistry.

Antibacterial substances of low molecular weight isolated from the blowfly, Lucilia sericata

Y. Shai, K. Mumcuoglu, S. Bhusare, 2007, Medical and veterinary entomology.

Short native antimicrobial peptides and engineered ultrashort lipopeptides: similarities and differences in cell specificities and modes of action

Maria Luisa Mangoni, Y. Shai, M. Mangoni, 2011, Cellular and Molecular Life Sciences.

Exploring peptide membrane interaction using surface plasmon resonance: differentiation between pore formation versus membrane disruption by lytic peptides.

Niv Papo, Y. Shai, N. Papo, 2003, Biochemistry.

Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study.

Y. Shai, Z. Oren, Y Shai, 1997, Biochemistry.

Ultrashort Peptide Bioconjugates Are Exclusively Antifungal Agents and Synergize with Cyclodextrin and Amphotericin B

Y. Shai, H. Sahl, Christopher J. Arnusch, 2011, Antimicrobial Agents and Chemotherapy.

In Vitro Activity and Potency of an Intravenously Injected Antimicrobial Peptide and Its dl Amino Acid Analog in Mice Infected with Bacteria

Niv Papo, Y. Shai, N. Papo, 2004, Antimicrobial Agents and Chemotherapy.

W-Band pulse EPR distance measurements in peptides using Gd(3+)-dipicolinic acid derivatives as spin labels.

Y. Shai, Michal Gordon-Grossman, Yana Gofman, 2011, Physical chemistry chemical physics : PCCP.

Controlled alteration of the shape and conformational stability of alpha-helical cell-lytic peptides: effect on mode of action and cell specificity.

Alessandro Tossi, Niv Papo, Sabrina Pacor, 2005, The Biochemical journal.

Molecular recognition between membrane-spanning polypeptides.

Y. Shai, 1995, Trends in biochemical sciences.

Bacterial resistance to antimicrobial peptides.

Y. Shai, H. Sahl, 2015, Biochimica et biophysica acta.

Host defense peptides as new weapons in cancer treatment

Y. Shai, N. Papo, 2005, Cellular and Molecular Life Sciences CMLS.

Why Bacillus thuringiensis insecticidal toxins are so effective: unique features of their mode of action.

Y. Shai, A. Aronson, 2001, FEMS microbiology letters.

Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.

Y. Shai, J. C. Lerman, Z. Oren, 1999, The Biochemical journal.

Functional, Conformational, and Molecular Modelling Studies of Voltage-Sensitivity and Selectivity of Synthetic Peptides Derived from Ion Channels

J. Breed, Y. Shai, M. Sansom, 1996 .

Diastereomers of Cytolysins, a Novel Class of Potent Antibacterial Peptides (*)

Y. Shai, Z. Oren, Y Shai, 1996, The Journal of Biological Chemistry.

Sequencing and synthesis of pardaxin, a polypeptide from the Red Sea Moses sole with ionophore activity

J. Fox, Y. Shai, P. Lazarovici, 1988, FEBS letters.

Energetics of ErbB1 transmembrane domain dimerization in lipid bilayers.

K. Hristova, Y. Shai, Lirong Chen, 2009, Biophysical journal.

Mode of Membrane Interaction and Fusogenic Properties of a de Novo Transmembrane Model Peptide Depend on the Length of the Hydrophobic Core*

B. Charloteaux, Annick Thomas, R. Brasseur, 2007, Journal of Biological Chemistry.

Inhibition of Fungal and Bacterial Plant Pathogens In Vitro and In Planta with Ultrashort Cationic Lipopeptides

Y. Shai, A. Makovitzki, I. Chet, 2007, Applied and Environmental Microbiology.

Transmembrane domains interactions within the membrane milieu: principles, advances and challenges.

Y. Shai, A. Fink, Neta Sal-Man, 2012, Biochimica et biophysica acta.

Pardaxin: channel formation by a shark repellant peptide from fish.

Y. Shai, 1994, Toxicology.

Interfering with the Dimerization of the ErbB Receptors by Transmembrane Domain-Derived Peptides Inhibits Tumorigenic Growth in Vitro and in Vivo.

Erez M. Bublil, Y. Yarden, Y. Shai, 2016, Biochemistry.

Self-association and subcellular localization of Puumala hantavirus envelope proteins

Y. Shai, A. Herrmann, S. Chiantia, 2019, Scientific Reports.

Selective Cytotoxicity of Dermaseptin S3 toward IntraerythrocyticPlasmodium falciparum and the Underlying Molecular Basis*

Y. Shai, A. Mor, D. Mazier, 1997, The Journal of Biological Chemistry.

Effect of natural L- to D-amino acid conversion on the organization, membrane binding, and biological function of the antimicrobial peptides bombinins H.

Maria Luisa Mangoni, Niv Papo, Luis Rivas, 2006, Biochemistry.

Preassembly of membrane-active peptides is an important factor in their selectivity toward target cells.

Neta Sal-Man, Y. Shai, Z. Oren, 2002, Biochemistry.

Rotary-door flap in laryngotracheal reconstruction.

Y. Shai, A. Marcovich, I. Eliachar, 1984, Archives of otolaryngology.

Mapping out the intricate relationship of the HIV envelope protein and the membrane environment.

Y. Shai, R. Schwarzer, Yoel A. Klug, 2017, Biochimica et Biophysica Acta - Biomembranes.

A synthetic peptide corresponding to a conserved heptad repeat domain is a potent inhibitor of Sendai virus‐cell fusion: an emerging similarity with functional domains of other viruses.

Y. Shai, D. Rapaport, D. Rapaport, 1995, The EMBO journal.

Suppression of Soft Tissue Sarcoma Growth by a Host Defense-Like Lytic Peptide

F. Jacobsen, Y. Shai, L. Steinstraesser, 2011, PloS one.

Molecular Recognition in the Membrane: Role in the Folding of Membrane Proteins

Y. Shai, 2002 .

The HIV gp41 Fusion Protein Inhibits T-Cell Activation through the Lentiviral Lytic Peptide 2 Motif.

V. Rotter, Y. Shai, R. Schwarzer, 2019, Biochemistry.

The Transmembrane Domain of HIV-1 gp41 Inhibits T-Cell Activation by Targeting Multiple T-Cell Receptor Complex Components through Its GxxxG Motif.

Y. Shai, E. Reuven, Yoel A. Klug, 2016, Biochemistry.

Bistable Bacterial Growth Dynamics in the Presence of Antimicrobial Agents

V. Rom-Kedar, Y. Shai, Ron Saar Dover, 2018, bioRxiv.

Loss of the Periplasmic Chaperone Skp and Mutations in the Efflux Pump AcrAB-TolC Play a Role in Acquired Resistance to Antimicrobial Peptides in Salmonella typhimurium

Y. Shai, A. Savidor, Roman G. Gerlach, 2020, Frontiers in Microbiology.

T‐Cell inactivation and immunosuppressive activity induced by HIV gp41 via novel interacting motif

Doron Gerber, Tomer Cohen, I. Cohen, 2007, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

HIV-1 fusion peptide targets the TCR and inhibits antigen-specific T cell activation.

I. Cohen, F. Quintana, Y. Shai, 2005, The Journal of clinical investigation.

d-Amino acids incorporation in the frog skin-derived peptide esculentin-1a(1-21)NH2 is beneficial for its multiple functions

A. Pini, Y. Shai, M. Mangoni, 2015, Amino Acids.

Oncolytic Activities of Host Defense Peptides

Sammy Al-Benna, F. Jacobsen, Y. Shai, 2011, International journal of molecular sciences.

Sendai virus N-terminal fusion peptide consists of two similar repeats, both of which contribute to membrane fusion.

S. Peisajovich, Y. Shai, R. Epand, 2002, European journal of biochemistry.

New insights into the mechanism of virus-induced membrane fusion.

S. Peisajovich, Y. Shai, 2002, Trends in biochemical sciences.

Methods for Investigating Biofilm Inhibition and Degradation by Antimicrobial Peptides.

Y. Shai, L. Segev-Zarko, 2017, Methods in molecular biology.

Molecular Recognition within the Membrane Milieu: Implications for the Structure and Function of Membrane Proteins

Y. Shai, 2001, The Journal of Membrane Biology.

Interaction of D-amino acid incorporated analogues of pardaxin with membranes.

Y. Shai, Y. Pouny, 1992, Biochemistry.

Effect of the hydrophobicity to net positive charge ratio on antibacterial and anti-endotoxin activities of structurally similar antimicrobial peptides.

Y. Shai, Yosef Rosenfeld, N. Lev, 2010, Biochemistry.

Synthetic peptides corresponding to the calmodulin-binding domains of skeletal muscle myosin light chain kinase and human erythrocyte Ca2+ pump interact with and permeabilize liposomes and cell membranes.

T. Vorherr, Y. Shai, E. Carafoli, 1993, Biochemistry.

Current development of analytical affinity chromatography: Design and biotechnological uses of molecular recognition surfaces

P. Caliceti, Y. Shai, I. Chaiken, 1988 .

Functional Domains within Fusion Proteins: Prospectives for Development of Peptide Inhibitors of Viral Cell Fusion

Y. Shai, 2000, Bioscience reports.

A Peptide Derived from a Conserved Domain of Sendai Virus Fusion Protein Inhibits Virus-Cell Fusion

Y. Shai, J. K. Ghosh, 1998, The Journal of Biological Chemistry.

What studies of fusion peptides tell us about viral envelope glycoprotein-mediated membrane fusion (review).

S. Durell, J. Ruysschaert, Y. Shai, 1997, Molecular membrane biology.

Fractal properties of macrophage membrane studied by AFM.

Y. Shai, A. Bitler, R. Dover, 2012, Micron.

Effect of PhoP-PhoQ Activation by Broad Repertoire of Antimicrobial Peptides on Bacterial Resistance*

Y. Shai, Tal Shprung, P. Trieu-Cuot, 2011, The Journal of Biological Chemistry.

Conjugation of fatty acids with different lengths modulates the antibacterial and antifungal activity of a cationic biologically inactive peptide.

Y. Shai, Yechiel Shai, Amir Malina, 2005, The Biochemical journal.

Cytoplasmic and Extracellular IsK Peptides Activate Endogenous K and Cl Channels in Xenopus Oocytes

B. Attali, Y. Shai, I. Ben-Efraim, 1996, The Journal of Biological Chemistry.

Neutralization of pro‐inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis

Steffen Jung, Y. Shai, Z. Porat, 2016, The EMBO journal.

pH-dependent antifungal lipopeptides and their plausible mode of action.

Y. Shai, A. Makovitzki, Yechiel Shai, 2005, Biochemistry.

Peptide-Lipid Interaction: Shedding Light into the Mode of Action and Cell Specificity of Antimicrobial Peptides

Y. Shai, 2006 .

Multifaceted action of Fuzeon as virus-cell membrane fusion inhibitor.

Y. Shai, A. Ashkenazi, Yael Wexler-Cohen, 2011, Biochimica et biophysica acta.

Membrane-Anchored HIV-1 N-Heptad Repeat Peptides Are Highly Potent Cell Fusion Inhibitors via an Altered Mode of Action

Y. Shai, Yael Wexler-Cohen, 2009, PLoS Pathogens.

Structurally Altered Peptides Reveal an Important Role for N-terminal Heptad Repeat Binding and Stability in the Inhibitory Action of HIV-1 Peptide DP178*

Robert Blumenthal, Anu Puri, Y. Shai, 2006, Journal of Biological Chemistry.

C-terminal Octylation Rescues an Inactive T20 Mutant

Robert Blumenthal, Sergio G. Peisajovich, S. A. Gallo, 2003, Journal of Biological Chemistry.

Anticancer Drug Colchicine Increases Disorder and Reduces Complexity in the Macrophage Membrane

Y. Shai, A. Bitler, R. Dover, 2016 .

NMR structure and binding of esculentin-1a (1-21)NH2 and its diastereomer to lipopolysaccharide: Correlation with biological functions.

Y. Shai, A. Bhunia, M. Mangoni, 2016, Biochimica et biophysica acta.

Thermodynamics of melittin binding to lipid bilayers. Aggregation and pore formation.

Y. Shai, T. Schulthess, J. Seelig, 2009, Biochemistry.

Viral fusion proteins: multiple regions contribute to membrane fusion.

S. Peisajovich, Y. Shai, 2003, Biochimica et biophysica acta.

Mode of action of linear amphipathic alpha-helical antimicrobial peptides.

Y. Shai, Z. Oren, Y Shai, 1998, Biopolymers.

Rapid entry of bitter and sweet tastants into liposomes and taste cells: implications for signal transduction.

Y. Shai, V. Krizhanovsky, S. Nir, 2000, American journal of physiology. Cell physiology.

Esculentin-1a-Derived Peptides Promote Clearance of Pseudomonas aeruginosa Internalized in Bronchial Cells of Cystic Fibrosis Patients and Lung Cell Migration: Biochemical Properties and a Plausible Mode of Action

A. Pini, Y. Shai, M. Mangoni, 2016, Antimicrobial Agents and Chemotherapy.

Mechanisms of biofilm inhibition and degradation by antimicrobial peptides.

Y. Shai, V. Brumfeld, M. Mangoni, 2015, The Biochemical journal.

Cyclization of a cytolytic amphipathic alpha-helical peptide and its diastereomer: effect on structure, interaction with model membranes, and biological function.

Y. Shai, Z. Oren, 2000, Biochemistry.

Structure and organization of hemolytic and nonhemolytic diastereomers of antimicrobial peptides in membranes.

Y. Shai, J. Hong, Z. Oren, 1999, Biochemistry.

A Repertoire of Novel Antibacterial Diastereomeric Peptides with Selective Cytolytic Activity*

Jiang Hong, Y. Shai, Z. Oren, 1997, The Journal of Biological Chemistry.

Analysis of in vitro activities and modes of action of synthetic antimicrobial peptides derived from an alpha-helical 'sequence template'.

Y. Shai, H. Sahl, A. Tossi, 2008, The Journal of antimicrobial chemotherapy.

Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides.

Y. Shai, A. Makovitzki, Yechiel Shai, 2009, Cancer research.

HIV-1 fusion protein exerts complex immunosuppressive effects.

Y. Shai, A. Ashkenazi, Omri Faingold, 2013, Trends in biochemical sciences.

HIV gp41: A Viral Membrane Fusion Machine

S. Peisajovich, Y. Shai, 2005 .

A leucine zipper motif in the ectodomain of Sendai virus fusion protein assembles in solution and in membranes and specifically binds biologically-active peptides and the virus.

Y. Shai, J. K. Ghosh, M. Ovadia, 1997, Biochemistry.

Structural and functional characterization of the alpha 5 segment of Bacillus thuringiensis delta-endotoxin.

Y. Shai, E. Gazit, 1993, Biochemistry.

Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site

Y. Shai, R. Blumenthal, Z. Porat, 2014, The Biochemical journal.

D‐enantiomer peptide of the TCRa transmembrane domain inhibits T‐cell activation in vitro and in vivo

I. Cohen, F. Quintana, Y. Shai, 2005, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Peptide-bilayer interactions: simulations of dermaseptin B, an antimicrobial peptide.

Y. Shai, M. Sansom, P. La Rocca, 1999, Biophysical chemistry.

Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia-mediated neurodegeneration

Y. Shai, Z. Porat, Yoel A. Klug, 2017, The Journal of Biological Chemistry.

An Immunomodulating Motif of the HIV-1 Fusion Protein Is Chirality-independent

A. Ben-nun, Y. Shai, A. Ashkenazi, 2013, The Journal of Biological Chemistry.

Structural and Functional Properties of the Membranotropic HIV-1 Glycoprotein gp41 Loop Region Are Modulated by Its Intrinsic Hydrophobic Core*

Y. Shai, Shuwen Liu, A. Ashkenazi, 2013, The Journal of Biological Chemistry.

Functional and structural characterization of HIV-1 gp41 ectodomain regions in phospholipid membranes suggests that the fusion-active conformation is extended.

Y. Shai, Yechiel Shai, Ofir Korazim, 2006, Journal of molecular biology.

Suppression of Human Prostate Tumor Growth in Mice by a Cytolytic d-, l-Amino Acid Peptide

Y. Shai, N. Papo, Z. Eshhar, 2004, Cancer Research.

Two Motifs within a Transmembrane Domain, One for Homodimerization and the Other for Heterodimerization*

Y. Shai, Neta Sal-Man, Doron Gerber, 2004, Journal of Biological Chemistry.

Structures and mode of membrane interaction of a short alpha helical lytic peptide and its diastereomer determined by NMR, FTIR, and fluorescence spectroscopy.

J. Ramesh, Y. Shai, D. Avrahami, 2002, European journal of biochemistry.

In Vivo Detection of Hetero-association of Glycophorin-A and Its Mutants within the Membrane*

Y. Shai, Doron Gerber, 2001, The Journal of Biological Chemistry.

A comparative study on the structure and function of a cytolytic α‐helical peptide and its antimicrobial β‐sheet diastereomer

Y. Shai, Z. Oren, Jiang Hong, 1999 .

The composition rather than position of polar residues (QxxS) drives aspartate receptor transmembrane domain dimerization in vivo.

Y. Shai, Neta Sal-Man, Doron Gerber, 2004, Biochemistry.

Efficient Clearance of Aspergillus fumigatus in Murine Lungs by an Ultrashort Antimicrobial Lipopeptide, Palmitoyl-Lys-Ala-dAla-Lys

A. Beauvais, J. Latgé, Steffen Jung, 2008, Antimicrobial Agents and Chemotherapy.

Interaction of Pexiganan (MSI-78)-Derived Analogues Reduces Inflammation and TLR4-Mediated Cytokine Secretion: A Comparative Study

Y. Shai, O. Franco, Z. Porat, 2023, ACS omega.

A GxxxG-like Motif within HIV-1 Fusion Peptide Is Critical to Its Immunosuppressant Activity, Structure, and Interaction with the Transmembrane Domain of the T-cell Receptor*

Y. Shai, Omri Faingold, Tomer Cohen, 2012, The Journal of Biological Chemistry.

HIV-1 gp41 and TCRα Trans-Membrane Domains Share a Motif Exploited by the HIV Virus to Modulate T-Cell Proliferation

I. Cohen, Y. Shai, S. Cohen, 2010, PLoS pathogens.

Erratum to “The HIV Fusion Peptide Adopts Intermolecular Parallel β-Sheet Structure in Membranes when Stabilized by the Adjacent N-Terminal Heptad Repeat: A 13C FTIR Study” [J. Mol. Biol. (2005) 350, 790–805]

Y. Shai, Kelly Sackett, 2005 .

Antisense peptide recognition of sense peptides: sequence simplification and evaluation of forces underlying the interaction.

Y. Shai, I. Chaiken, T. Brunck, 1989, Biochemistry.

Comparative analysis of membrane-associated fusion peptide secondary structure and lipid mixing function of HIV gp41 constructs that model the early pre-hairpin intermediate and final hairpin conformations.

Y. Shai, R. Epand, R. Epand, 2010, Journal of molecular biology.

Proline localized to the interaction interface can mediate self-association of transmembrane domains.

Y. Shai, Neta Sal-Man, Doron Gerber, 2014, Biochimica et biophysica acta.

Hetero-assembly between all-L- and all-D-amino acid transmembrane domains: forces involved and implication for inactivation of membrane proteins.

Y. Shai, Neta Sal-Man, Doron Gerber, 2004, Journal of molecular biology.

Mechanism of Membrane Permeation and Pore Formation by Antimicrobial Peptides

Y. Shai, 2006 .

The alpha-5 segment of Bacillus thuringiensis delta-endotoxin: in vitro activity, ion channel formation and molecular modelling.

Y. Shai, M. Sansom, E. Gazit, 1994, The Biochemical journal.

S. Peisajovich, Y. Shai, 2002, AIDS research and human retroviruses.

«Mediator methodology» for the synthesis of peptides in a two-polymeric system

K. Jacobson, Y. Shai, A. Patchornik, 1985 .

“MEDIATOR METHODOLOGY” FOR THE SYNTHESIS OF PEPTIDES IN A TWO-POLYMERIC SYSTEM

K. Jacobson, Y. Shai, A. Patchornik, 1985 .

1 ENDOTOXIN ( LPS ) NEUTRALIZATION BY INNATE IMMUNITY HOST-DEFENSE PEPTIDES : PEPTIDES ’ PROPERTIES AND PLAUSIBLE MODES OF ACTION

Y. Shai, N. Papo, Yosef Rosenfeld, 2005 .

A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model.

I. Cohen, F. Quintana, Y. Shai, 2007, Biochemistry.

The role of the N-terminal heptad repeat of HIV-1 in the actual lipid mixing step as revealed by its substitution with distant coiled coils.

Y. Shai, Yael Wexler-Cohen, Kelly Sackett, 2005, Biochemistry.

Like Lytic Peptide − Systemic Inoculation of a Host Defense Metastases in Human Prostate and Breast Xenografts by Inhibition of Tumor Growth and Elimination of Multiple

H. Degani, Y. Shai, N. Papo, 2006 .

Synthetic Ultrashort Cationic Lipopeptides Induce Systemic Plant Defense Responses against Bacterial and Fungal Pathogens

Y. Shai, A. Makovitzki, I. Chet, 2009, Applied and Environmental Microbiology.

Mechanisms of biofilm inhibition and degradation by antimicrobial peptides.

Y. Shai, V. Brumfeld, M. Mangoni, 2015, The Biochemical journal.

Suppression of human solid tumor growth in mice by intratumor and systemic inoculation of histidine-rich and pH-dependent host defense-like lytic peptides.

Y. Shai, A. Makovitzki, A. Fink, 2009, Cancer research.

Antimicrobial lipopolypeptides composed of palmitoyl Di- and tricationic peptides: in vitro and in vivo activities, self-assembly to nanostructures, and a plausible mode of action.

Y. Shai, A. Makovitzki, J. Baram, 2008, Biochemistry.

Host defense peptides and lipopeptides: modes of action and potential candidates for the treatment of bacterial and fungal infections.

Y. Shai, D. Avrahami, Arik Makovitzky, 2006, Current protein & peptide science.

Neutralization of pro‐inflammatory monocytes by targeting TLR2 dimerization ameliorates colitis

Steffen Jung, Y. Shai, Z. Porat, 2016, The EMBO journal.

Biosensors Based on Solvated Bilayers Attached to Electrodes

I. Rubinstein, Y. Shai, H. Garty, 1991 .

Development of Nontoxic Peptides for Lipopolysaccharide Neutralization and Sepsis Treatment

Y. Shai, Christopher J. Arnusch, N. A. Wani, 2024, ACS Pharmacology & Translational Science.

Study of the Basis for Toxicity and Specificity of Bacillus thuringiensis d-Endotoxins

Y. Shai, B. Sneh, A. Zilberstein, 1996 .

Synthetic Peptides and the Design of Peptide and Protein Recognition Surfaces

Y. Shai, I. Chaiken, G. Fassina, 1987 .