I. Chaiken

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Anti-sense peptide recognition of sense peptides: direct quantitative characterization with the ribonuclease S-peptide system using analytical high-performance affinity chromatography.

Y. Shai, M. Flashner, I. Chaiken, 1987, Biochemistry.

Nature of the charged-group effect on the stability of the C-peptide helix.

P. S. Kim, R. L. Baldwin, S. Marqusee, 1985, Proceedings of the National Academy of Sciences of the United States of America.

Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus.

I. Chaiken, C. Abrams, Amos B. Smith, 2018, The Biochemical journal.

Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors.

Md. Alamgir Hossain, M. Kutzler, I. Chaiken, 2020, Biochemistry.

Modular, self‐assembling peptide linkers for stable and regenerable carbon nanotube biosensor interfaces

Jimmy Xu, I. Chaiken, Jimmy Xu, 2006, Journal of molecular recognition : JMR.

Proteins, recognition networks and developing interfaces for macromolecular biosensing

I. Chaiken, M. Sergi, J. Zurawski, 2004, Journal of molecular recognition : JMR.

Kinetic analysis of a protein antigen-antibody interaction limited by mass transport on an optical biosensor.

M. Doyle, I. Chaiken, D. Myszka, 1997, Biophysical chemistry.

Molecular diversity and combinatorial chemistry : libraries and drug discovery

Kim D. Janda, I. Chaiken, K. Janda, 1996 .

Monomeric isomers of human interleukin 5 show that 1:1 receptor recruitment is sufficient for function.

M. Doyle, R. Cook, D. Mcnulty, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Peptide-small molecule hybrids via orthogonal deprotection-chemoselective conjugation to cysteine-anchored scaffolds. A model study.

I. Chaiken, S. Savinov, Amos B. Smith, 2002, Organic letters.

Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.

M. Kutzler, I. Chaiken, Y. Long, 2018, Journal of medicinal chemistry.

Broad-Spectrum Anti-Human Immunodeficiency Virus (HIV) Potential of a Peptide HIV Type 1 Entry Inhibitor

I. Chaiken, C. Cicala, J. Arthos, 2007, Journal of Virology.

A model of peptide triazole entry inhibitor binding to HIV-1 gp120 and the mechanism of bridging sheet disruption.

C. Bewley, Judith M. LaLonde, I. Chaiken, 2013, Biochemistry.

Conformational and structural features of HIV-1 gp120 underlying the dual receptor antagonism by cross-reactive neutralizing antibody m18.

D. Dimitrov, J. Gershoni, E. Freire, 2011, Biochemistry.

Click Chemistry on Azidoproline: High‐Affinity Dual Antagonist for HIV‐1 Envelope Glycoprotein gp120

Kalyan C. Tirupula, I. Chaiken, H. Gopi, 2006, ChemMedChem.

Analysis of the interaction between the HIV-inactivating protein cyanovirin-N and soluble forms of the envelope glycoproteins gp120 and gp41.

M. Boyd, D. Xie, I. Chaiken, 2000, Molecular pharmacology.

Monoclonal antibody m18 paratope leading to dual receptor antagonism of HIV-1 gp120.

D. Dimitrov, I. Chaiken, Mei-Yun Zhang, 2011, Biochemistry.

Active site properties of (aspartic acid 43)-semisynthetic nuclease-T'.

I. Chaiken, G. R. Sánchez, G. Sánchez, 1972, The Journal of biological chemistry.

Biosensor analysis of receptor-ligand interactions.

I. Chaiken, Sheng‐Jiun Wu, 2004, Methods in molecular biology.

Quantitative affinity chromatography. Determination of binding constants by elution with competitive inhibitors.

B. Dunn, I. Chaiken, 1974, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of ribonuclease-nucleotide interactions by quantitative affinity chromatography.

H. C. Taylor, I. Chaiken, 1976, The Journal of biological chemistry.

Preparative and analytical affinity chromatography of neurophysins on methionyl-tyrosyl-phenylalanyl-aminohexyl-agarose.

I. Chaiken, 1979, Analytical biochemistry.

Quantitative uses of affinity chromatography.

I. Chaiken, 1979, Analytical biochemistry.

Expression of multivalency in the affinity chromatography of antibodies. Appendix: Derivation and evaluation of equations for independent bivalent interacting systems in quantitative affinity chromatography.

I. Chaiken, D. Eilat, W. McCormick, 1979, Biochemistry.

Interdependence of neurophysin self-association and neuropeptide hormone binding as expressed by quantitative affinity chromatography.

I. Chaiken, S. Angal, 1982, Biochemistry.

Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate.

I. Chaiken, C. Abrams, B. Parajuli, 2020, The Biochemical journal.

Tissue factor regulates plasminogen binding and activation.

I. Chaiken, D. Cines, P. Larson, 1998, Blood.

Altered Env conformational dynamics as a mechanism of resistance to peptide-triazole HIV-1 inactivators

I. Chaiken, M. Root, Adel A Rashad, 2021, Retrovirology.

Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.

I. Chaiken, Adel A Rashad, Kriti Acharya, 2017, Organic & biomolecular chemistry.

Analysis of the interaction between human interleukin‐5 and the soluble domain of its receptor using a surface plasmon resonance biosensor

M. Doyle, P. Young, I. Chaiken, 1994, Journal of molecular recognition : JMR.

HIV‐1 ENV gp120 structural determinants for peptide triazole dual receptor site antagonism

J. Sodroski, Judith M. LaLonde, I. Chaiken, 2013, Proteins.

Effects of monomethoxypoly(ethylene glycol) modification of ribonuclease on antibody recognition, substrate accessibility and conformational stability

P. Caliceti, I. Chaiken, F. Veronese, 1990, Journal of molecular recognition : JMR.

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry

M. Kutzler, I. Chaiken, C. Abrams, 2021, Microorganisms.

Storage stability of the solution formulation of sCD4 determined by DSC in comparison with two functional assays

I. Chaiken, D. Myszka, C. Brouillette, 1996 .

Molecular interaction analysis in ligand design using mass transport, kinetic and thermodynamic methods

M. Doyle, I. Chaiken, D. Myszka, 1996, Journal of molecular recognition : JMR.

Multivalent and Flexible PEG-Nitrilotriacetic Acid Derivatives for Non-covalent Protein Pegylation

F. Veronese, I. Chaiken, G. Pasut, 2011, Pharmaceutical Research.

Pharmacokinetic stability of macrocyclic peptide triazole HIV‐1 inactivators alone and in liposomes

I. Chaiken, S. Wrenn, G. Pasut, 2019, Journal of peptide science : an official publication of the European Peptide Society.

High-performance liquid chromatographic mapping and structural characterization of neurophysin isoforms.

I. Chaiken, T. H. Miller, R. P. Sequeira, 1984, Analytical biochemistry.

Preparation and studies of 19 F-labeled and enriched 13 C-labeled semisynthetic ribonuclease-S' analogues.

J. R. Lyerla, I. Chaiken, J. Cohen, 1973, The Journal of biological chemistry.

Interleukin-5 Receptor Subunit Oligomerization and Rearrangement Revealed by Fluorescence Resonance Energy Transfer Imaging*

I. Chaiken, T. Ishino, M. Zaks-Zilberman, 2008, Journal of Biological Chemistry.

Use of enzymes in peptide synthesis

I. Chaiken, M. Ohno, F. Widmer, 1982, Applied biochemistry and biotechnology.

Interleukin 5 interactions with soluble and cell surface forms of its receptor

R. Cook, I. Chaiken, Jun Li, 1996, Journal of molecular recognition : JMR.

Mutants of Single Chain Interleukin 5 Show Asymmetric Recruitment of Receptor α and βc Subunits*

R. Cook, I. Chaiken, Jun Li, 1996, The Journal of Biological Chemistry.

Neutralizing monoclonal antibodies can potentiate IL‐5 signaling

J. Tavernier, J. Vandekerckhove, P. Heinrich, 2001, European journal of immunology.

Irreversible HIV-1 Inactivation Employing a Small Molecule Dual-Action Virolytic Entry Inhibitor Strategy

I. Chaiken, C. Abrams, Alamgir Hossain, 2019 .

Heterogeneity of anti-phospholipid and anti-endothelial cell antibodies.

I. Chaiken, D. Cines, L. Silberstein, 1998, Journal of autoimmunity.

Construction and Binding Kinetics of a Soluble Granulocyte-Macrophage Colony-stimulating Factor Receptor α-Chain-Fc Fusion Protein*

I. Chaiken, G. Canziani, Q. Fang, 1998, The Journal of Biological Chemistry.

Enzymatic condensation of nonassociated peptide fragments using a molecular trap.

I. Chaiken, G. Homandberg, A. Komoriya, 1982, Biochemistry.

HIV-1 Env-Dependent Cell Killing by Bifunctional Small-Molecule/Peptide Conjugates.

Md. Alamgir Hossain, I. Chaiken, C. Abrams, 2021, ACS chemical biology.

Semisynthetic peptides and proteins.

I. Chaiken, 1981, CRC critical reviews in biochemistry.

Impact of HIV-1 Membrane Cholesterol on Cell-Independent Lytic Inactivation and Cellular Infectivity.

I. Chaiken, C. Abrams, S. Wrenn, 2016, Biochemistry.

Synthesis, purification, and properties of a semisynthetic ribonuclease S incorporating 4-fluoro-L-histidine at position 12.

B. Dunn, I. Chaiken, K. Kirk, 1974, The Journal of biological chemistry.

Molecular diagnostics using analytical immuno high performance liquid affinity chromatography

P. Caliceti, I. Chaiken, G. Fassina, 1987, Applied biochemistry and biotechnology.

Cell‐Free HIV‐1 Virucidal Action by Modified Peptide Triazole Inhibitors of Env gp120

I. Chaiken, E. Papazoglou, M. Contarino, 2011, ChemMedChem.

Characterization of the size and 5' cap of messenger RNA encoding neurophysin precursors.

I. Chaiken, C. Hough, 1984, Nucleic acids research.

Tissue Factor Regulates Plasminogen Binding and Activation

I. Chaiken, D. Cines, A. Higazi, 1998 .

Affinity capture of [Arg8]vasopressin-receptor complex using immobilized antisense peptide.

N. Aiyar, I. Chaiken, F. Lu, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Mutagenesis in the C-terminal region of human interleukin 5 reveals a central patch for receptor alpha chain recognition.

R. Cook, I. Chaiken, J. Li, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Broad-Spectrum Anti-Human Immunodeﬁciency Virus (HIV) Potential of a Peptide HIV Type 1 Entry Inhibitor (cid:1)

I. Chaiken, C. Cicala, J. Arthos, 2007 .

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

J. Hoxie, I. Chaiken, J. Jacobson, 2013, Retrovirology.

From receptor recognition mechanisms to bioinspired mimetic antagonists in HIV-1/cell docking.

I. Chaiken, C. Dowd, C. Li, 2001, Journal of chromatography. B, Biomedical sciences and applications.

Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration.

I. Chaiken, D. Myszka, T. Morton, 1995, Analytical biochemistry.

Improved Durability to SARS-CoV-2 Vaccine Immunity following Coimmunization with Molecular Adjuvant Adenosine Deaminase-1

Emma A. Gordon, D. Weiner, M. Kutzler, 2022, The Journal of Immunology.

HIV Envelope Binding by Macrophage-Expressed gp340 Promotes HIV-1 Infection1

D. Weissman, I. Chaiken, D. Malamud, 2008, The Journal of Immunology.

Conformational changes of gp120 in epitopes near the CCR5 binding site are induced by CD4 and a CD4 miniprotein mimetic.

J. Sodroski, R. Wyatt, W. Hendrickson, 1999, Biochemistry.

Abasic Phosphorothioate Oligomers Inhibit HIV-1 Reverse Transcription and Block Virus Transmission across Polarized Ectocervical Organ Cultures

Phalguni Gupta, I. Chaiken, B. Wigdahl, 2014, Antimicrobial Agents and Chemotherapy.

Antibody 17b binding at the coreceptor site weakens the kinetics of the interaction of envelope glycoprotein gp120 with CD4.

J. Sodroski, R. Wyatt, I. Chaiken, 2001, Biochemistry.

Molecular Adjuvant Adenosine Deaminase-1 Immunity following Coimmunization with Improved Durability to SARS-CoV-2 Vaccine

Emma A. Gordon, M. Kutzler, I. Chaiken, 2022 .

Biosensor analysis of dynamics of interleukin 5 receptor subunit beta(c) interaction with IL5:IL5R(alpha) complexes.

I. Chaiken, D. V. Van Ryk, G. Canziani, 2002, Analytical biochemistry.

Reaction of chloroacetamide with the sulfhydryl group of papain.

I. Chaiken, E. L. Smith, 1969, The Journal of biological chemistry.

Reaction of the sulfhydryl group of papain with chloroacetic acid.

I. Chaiken, E. L. Smith, 1969, The Journal of biological chemistry.

Real‐time monitoring of the membrane‐binding and insertion properties of the cholesterol‐dependent cytolysin anthrolysin O from Bacillus anthracis

I. Chaiken, P. Loll, M. Jost, 2006, Journal of molecular recognition : JMR.

Interactions of peptide triazole thiols with Env gp120 induce irreversible breakdown and inactivation of HIV-1 virions

J. Hoxie, I. Chaiken, J. Jacobson, 2013, Retrovirology.

Cooperative interactions in neurophysin-neuropeptide hormone complexes. Analytical affinity chromatography of native and covalently-modified neurophysins.

I. Chaiken, H. Tamaoki, S. Angal, 2009, International journal of peptide and protein research.

High-performance liquid chromatography and studies of neurophysin-neurohypophysial hormone pathways.

I. Chaiken, H. Swaisgood, T. Kanmera, 1984, Journal of chromatography.

Neurophysin–neuropeptide hormone complexes: Biosynthetic origin and noncovalent interactions

I. Chaiken, 1983, Biopolymers.

Effects of limited tryptic proteolysis of bovine neurophysins on molecular properties of hormone binding, self-association, and antigenicity.

I. Chaiken, S. Angal, R. P. Sequeira, 1982, Biochemistry.

An overview of affinity chromatography.

M. Wilchek, I. Chaiken, 2000, Methods in molecular biology.

Design of a photoaffinity label for the hormone binding site of neurophysin.

I. Chaiken, W. McCormick, Y. Klausner, 2009, International journal of peptide and protein research.

Evaluation of quantitative affinity chromatography by comparison with kinetic and equilibrium dialysis methods for the analysis of nucleotide binding to staphylococcal nuclease.

B. Dunn, I. Chaiken, 1975, Biochemistry.

Analytical Affinity Chromatography

I. Chaiken, 1987 .

The HIV-1 Env gp120 Inner Domain Shapes the Phe43 Cavity and the CD4 Binding Site

J. Sodroski, F. Kirchhoff, B. Hahn, 2020, mBio.

Carbon-13 nuclear-magnetic-resonance studies on selected amino acids, peptides, and proteins.

J. R. Lyerla, I. Chaiken, J. Cohen, 1973, European journal of biochemistry.

Click Chemistry in Peptide-Based Drug Design

I. Chaiken, Huiyuan Li, R. Aneja, 2013, Molecules.

Enzyme-catalyzed formation of semisynthetic staphylococcal nuclease using a new synthetic fragment, [48-glycine]synthetic-(6-49).

I. Chaiken, G. Homandberg, A. Komoriya, 2009, International journal of peptide and protein research.

AFFINITY CHROMATOGRAPHY STUDIES OF COOPERATIVE INTERACTIONS IN NEUROPHYSIN-NEUROPEPTIDE HORMONE COMPLEXES

I. Chaiken, H. Tamaoki, S. Angal, 1983 .

Minimum information content and formation of interacting ribonuclease fragment complexes.

I. Chaiken, G. Homandberg, A. Komoriya, 2009, International journal of peptide and protein research.

The complete amino acid sequence of papain. Additions and corrections.

I. Chaiken, E. L. Smith, R. Mitchel, 1970, The Journal of biological chemistry.

Conformational and immunochemical analysis of the cyanogen bromide fragments of thermolysin.

I. Chaiken, C. Vita, A. Fontana, 1979, Biochemistry.

Interactions of free and immobilized myelin basic protein with anionic detergents.

C. Campagnoni, A. Campagnoni, I. Chaiken, 1981, Biochemistry.

Antiviral Breadth and Combination Potential of Peptide Triazole HIV-1 Entry Inhibitors

F. Krebs, I. Chaiken, R. Shattock, 2011, Antimicrobial Agents and Chemotherapy.

Microenvironment of histidine 12 in ribonuclease-S as detected by 13C nuclear magnetic resonance.

I. Chaiken, J. Cohen, E. Sokoloski, 1974, Journal of the American Chemical Society.

MICROENVIRONMENT OF HISTIDINE 12 IN RIBONUCLEASE-S AS DETECTED BY (13)C NUCLEAR MAGNETIC RESONANCE

I. Chaiken, J. S. Cohen, E. Sokoloski, 1974 .

In Vitro Synthesis of Hypothalamic Neurophysin Precursors

L. Giudice, I. Chaiken, C. Hough, 1982 .

Current trends in molecular recognition and bioseparation.

P. Young, I. Chaiken, T. Porter, 1995, Journal of chromatography. A.

Peptide Triazole Inactivators of HIV-1 Utilize a Conserved Two-Cavity Binding Site at the Junction of the Inner and Outer Domains of Env gp120.

I. Chaiken, Huiyuan Li, Adel A Rashad, 2015, Journal of medicinal chemistry.

Salivary agglutinin inhibits HIV type 1 infectivity through interaction with viral glycoprotein 120.

Daniel Malamud, Zhiwei Wu, I. Chaiken, 2003, AIDS research and human retroviruses.

Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.

I. Chaiken, C. Abrams, Adel A Rashad, 2016, Biochemistry.

Expression, purification, and characterization of recombinant cyanovirin-N for vaginal anti-HIV microbicide development.

I. Chaiken, K. Watson, R. Buckheit, 2005, Protein expression and purification.

Macromolecular biorecognition : principles and methods

I. Chaiken, Consiglio naxionale delle ricerche, 1987 .

Making sense from antisense: A review of experimental data and developing ideas on sense–antisense peptide recognition

A Tropsha, A. Tropsha, I. Chaiken, 1992, Journal of molecular recognition : JMR.

Protein Recognition in Biology

I. Chaiken, J. Nickels, T. Ishino, 2008 .

Reaction of a specific tyrosine residue of papain with diisopropylfluorophosphate.

I. Chaiken, E. L. Smith, 1969, The Journal of biological chemistry.

Drug-protein interactions: evaluation of the binding of antipsychotic drugs to glutamate dehydrogenase by quantitative affinity chromatography.

F. Veronese, I. Chaiken, R. Bevilacqua, 1979, Molecular pharmacology.

Effect of neurophysin on enzymatic maturation of oxytocin from its precursor.

I. Chaiken, B. Eipper, S. Ando, 1988, Journal of Biological Chemistry.

Sequence simplification and the intra‐ and intermolecular self‐recognition properties of vasopressin/neurophysin biosynthetic precursor

I. Chaiken, G. Fassina, 1989, Journal of molecular recognition : JMR.

Cell-free biosynthesis of different high molecular weight forms of bovine neurophysins I and II coded by hypothalamic mRNA.

L. Giudice, I. Chaiken, 1979, The Journal of biological chemistry.

Isolation and sequence analysis of oxytocin from the sheep corpus luteum

I. Chaiken, J. Spiess, V. Choy, 1986, Neuropeptides.

Mechanical characterization of HIV‐1 with a solid‐state nanopore sensor

M. J. Kim, I. Chaiken, P. Dutta, 2018, Electrophoresis.

Solid-state nanopore detection of protein complexes: applications in healthcare and protein kinetics.

M. J. Kim, I. Chaiken, K. Freedman, 2013, Small.

HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites

Peter D. Kwong, Wayne A. Hendrickson, Michael L. Doyle, 2002, Nature.

Antibody Binding Is a Dominant Determinant of the Efficiency of Human Immunodeficiency Virus Type 1 Neutralization

J. Sodroski, I. Chaiken, Xinzhen Yang, 2006, Journal of Virology.

A recombinant allosteric lectin antagonist of HIV‐1 envelope gp120 interactions

I. Chaiken, R. Shattock, S. Cocklin, 2007, Proteins.

Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein.

T L Hoffman, W Zhang, R. Doms, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Chimeric Cyanovirin-MPER Recombinantly Engineered Proteins Cause Cell-Free Virolysis of HIV-1

I. Chaiken, C. Abrams, M. Contarino, 2013, Antimicrobial Agents and Chemotherapy.

Design and characterization of an intramolecular antiparallel coiled coil peptide.

I. Chaiken, D. Myszka, 1994, Biochemistry.

Mapping and isolation of large peptide fragments from bovine neurophysins and biosynthetic neurophysin-containing species by high-performance liquid chromatography.

I. Chaiken, C. Hough, Christopher J. Hough, 1980, Analytical biochemistry.

Characterization of HIV‐1 p24 self‐association using analytical affinity chromatography

J. Culp, C. Debouck, I. Chaiken, 1992, Proteins.

Cytokine recognition by human interleukin 5 receptor.

I. Chaiken, T. Ishino, N. Robertson, 2005, Vitamins and hormones.

Coiled coil miniprotein randomization on phage leads to charge pattern mimicry of the receptor recognition determinant of interleukin 5

I. Chaiken, J. R. White, John R White, 2002, Journal of molecular recognition : JMR.

Exploring biomolecular recognition using optical biosensors.

Gabriela Canziani, I. Chaiken, D. Cines, 1999, Methods.

Use of reverse-phase high-performance liquid chromatography in structural studies of neurophysins, photolabeled derivatives, and biosynthetic precursors.

H. Gainer, M. Brownstein, I. Chaiken, 1982, Analytical biochemistry.

The Case for S2: The Potential Benefits of the S2 Subunit of the SARS-CoV-2 Spike Protein as an Immunogen in Fighting the COVID-19 Pandemic

I. Chaiken, G. Canziani, E. Carter, 2021, Frontiers in Immunology.

Defensin promotes the binding of lipoprotein(a) to vascular matrix.

M. Koschinsky, J. Weisel, T. Ganz, 1999, Blood.

Bio-nano-optics for cellular investigations

I. Chaiken, Edward Keough, K. Pourrezaei, 2004, SPIE Optics East.

Analysis of macromolecular interactions using immobilized ligands.

I. Chaiken, R. Karlsson, R Karlsson, 1992, Analytical biochemistry.

Peptides 1982—Proceedings of the 17th European Peptide Symposium: Edited by K. Bláha and P. Malon̆, de Gruyter, Berlin, 1983. 846 pp. $134.00

I. Chaiken, 1984 .

Mechanism of Multivalent Nanoparticle Encounter with HIV-1 for Potency Enhancement of Peptide Triazole Virus Inactivation*

I. Chaiken, C. Abrams, M. Root, 2014, The Journal of Biological Chemistry.

IL-5-Induced JAB-JAK2 interaction.

A. Yoshimura, I. Chaiken, S. Zahn, 2000, Cytokine.

ON THE BIOSYNTHETIC ORIGIN OF NEUROPHYSIN-NEUROHYPOPHYSEAL PEPTIDE HORMONE COMPLEXES

I. Chaiken, P. Hargrave, C. Hough, 1980 .

Analytical high-performance affinity chromatography: evaluation by studies of neurophysin self-association and neurophysin-peptide hormone interaction using glass matrices.

I. Chaiken, H. Swaisgood, 1986, Biochemistry.

Current development of analytical affinity chromatography: Design and biotechnological uses of molecular recognition surfaces

P. Caliceti, Y. Shai, I. Chaiken, 1988 .

Active site ligand binding by an inactive ribonuclease S analogue. A quantitative affinity chromatographic study.

H. C. Taylor, I. Chaiken, 1977, The Journal of biological chemistry.

Domain characteristics of the carboxyl‐terminal fragment 206–316 of thermolysin

I. Chaiken, C. Vita, A. Fontana, 1983, Biopolymers.

Non‐natural Peptide Triazole Antagonists of HIV‐1 Envelope gp120

Mark Contarino, E. Freire, I. Chaiken, 2013, ChemMedChem.

Use of the quartz crystal microbalance to monitor ligand-induced conformational rearrangements in HIV-1 envelope protein gp120

E. Freire, I. Chaiken, Amos B. Smith, 2010, Analytical and bioanalytical chemistry.

Introducing metallocene into a triazole peptide conjugate reduces its off‐rate and enhances its affinity and antiviral potency for HIV‐1 gp120

I. Chaiken, Ferit Tuzer, S. Cocklin, 2009, Journal of molecular recognition : JMR.

A protein engineering approach differentiates the functional importance of carbohydrate moieties of interleukin-5 receptor α.

J. Tavernier, S. Lievens, I. Chaiken, 2011, Biochemistry.

Identifying structure-function relationships in four-helix bundle cytokines: towards de novo mimetics design.

I. Chaiken, W. V. Williams, Irwin M. Chaiken, 1996, Trends in biotechnology.

Enhanced EGFR inhibition and distinct epitope recognition by EGFR antagonistic MABS C225 and 425

I. Chaiken, U. Rodeck, C. Kari, 2008, Cancer biology & therapy.

Relationship between α-helical propensity and formation of the ribonuclease-S complex

B. Dunn, I. Chaiken, 1975 .

An activity from Escherichia coli membranes responsible for the modification of nitrate reductase to its precursor form.

I. Chaiken, G. Chaudhry, C. MacGregor, 1983, The Journal of biological chemistry.

Synthesis and properties of an all-D model ribonuclease S-peptide.

I. Chaiken, A. Fontana, C. Ponnamperuma, 2009, International journal of peptide and protein research.

Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.

I. Chaiken, Huiyuan Li, Adel A Rashad, 2015, ACS chemical biology.

Small-molecule inhibitors of HIV-1 entry block receptor-induced conformational changes in the viral envelope glycoproteins.

J. Sodroski, E. Freire, I. Chaiken, 2004, Proceedings of the National Academy of Sciences of the United States of America.

L-Asparaginase from Erwinia carotovora

I. Chaiken, S. Shifrin, B. Solis, 2003 .

Analytical affinity chromatography in studies of molecular recognition in biology: a review.

I. Chaiken, 1986, Journal of chromatography.

Recruitment pharmacophore for interleukin 5 receptor α antagonism

I. Chaiken, Madhushree Bhattacharya, B. Jameson, 2007 .

Asymmetric usage of antagonist charged residues drives interleukin-5 receptor recruitment but is insufficient for receptor activation.

I. Chaiken, Madhushree Bhattacharya, B. Jameson, 2006, Biochemistry.

Receptor Epitope Usage by an Interleukin-5 Mimetic Peptide*

I. Chaiken, Madhushree Bhattacharya, T. Ishino, 2005, Journal of Biological Chemistry.

Cyclic peptide interleukin 5 antagonists mimic CD turn recognition epitope for receptor α

I. Chaiken, Madhushree Bhattacharya, I. Uings, 2004, Biopolymers.

Revealing and utilizing receptor recognition mechanisms in a high‐throughput world

I. Chaiken, 2001, Journal of cellular biochemistry. Supplement.

Epitope Randomization Redefines the Functional Role of Glutamic Acid 110 in Interleukin-5 Receptor Activation*

Rabindra Tambyraja, I. Chaiken, Wentao Zhang, 2000, The Journal of Biological Chemistry.

Single Chain Human Interleukin 5 and Its Asymmetric Mutagenesis for Mapping Receptor Binding Sites (*)

I. Chaiken, K. Dede, Jun Li, 1996, The Journal of Biological Chemistry.

L-Asparaginase from Erwinia carotovora PHYSICOCHEMICAL

I. Chaiken, S. Shifrin, B. Solis, 2003 .

Mode of action for linear peptide inhibitors of HIV-1 gp120 interactions.

J. Sodroski, D. Burton, E. Freire, 2004, Biochemistry.

Cleaved high molecular weight kininogen binds directly to the integrin CD11b/CD18 (Mac-1) and blocks adhesion to fibrinogen and ICAM-1.

R. Colman, R. Heinrikson, I. Chaiken, 2000, Blood.

Folding of thermolysin fragments. Correlation between conformational stability and antigenicity of carboxyl-terminal fragments.

I. Chaiken, C. Vita, A. Fontana, 1985, European journal of biochemistry.

Preparation of biologically active conjugates of bovine neurophysins and other polypeptides with multi-(poly-D,L-alanyl)--poly-L-lysine and their use to elicit antibodies.

I. Chaiken, J. Curd, E. A. Fischer, 1977, Immunochemistry.

Interaction with CD4 and Antibodies to CD4-Induced Epitopes of the Envelope gp120 from a Microglial Cell-Adapted Human Immunodeficiency Virus Type 1 Isolate

Simon Cocklin, I. Chaiken, Francisco González-Scarano, 2005, Journal of Virology.

Covalent Conjugation of a Peptide Triazole to HIV-1 gp120 Enables Intramolecular Binding Site Occupancy

I. Chaiken, C. Abrams, Huiyuan Li, 2014, Biochemistry.

Controlled formation of model homo- and heterodimer coiled coil polypeptides.

I. Chaiken, D. Myszka, T. Graddis, 1993, Biochemistry.

Targeting cell surface HIV-1 Env protein to suppress infectious virus formation.

I. Chaiken, Yu-Hung Huang, F. Shaheen, 2017, Virus research.

Folding and Antigenicity of Thermolysin Fragments

I. Chaiken, C. Vita, A. Fontana, 1987 .

Kinetic characterization of the interaction of biotinylated human interleukin 5 with an Fc chimera of its receptor α subunit and development of an ELISA screening assay using real‐time interaction biosensor analysis

R. Hertzberg, P. Mcdonnell, I. Chaiken, 1995, Journal of molecular recognition : JMR.

Structural determinants for affinity enhancement of a dual antagonist peptide entry inhibitor of human immunodeficiency virus type-1.

J. Sodroski, F. Krebs, Judith M. LaLonde, 2008, Journal of medicinal chemistry.

Carbon 13 as a probe of helix formation in semisynthetic ribonuclease-S'.

I. Chaiken, 1974, Journal of Biological Chemistry.

Sequence redesign and the assembly mechanism of the oxytocin/bovine neurophysin I biosynthetic precursor.

I. Chaiken, S. Ando, P. McPhie, 1987, The Journal of biological chemistry.

CONFORMATIONAL EFFECTS ASSOCIATED WITH THE INTERACTION OF POLYPEPTIDE LIGANDS WITH NEUROPHYSINS

I. Chaiken, Irwin M. Chaiken, Raymond E. Randolph, 1975, Annals of the New York Academy of Sciences.

Real-Time Salmonella Detection Using Lead Zirconate Titanate-Titanium Microcantilevers

W. Shih, W. Shih, I. Chaiken, 2004 .

A study of the role of histidine residue 46 in staphylococcal nuclease by solid phase peptide synthesis.

C. Anfinsen, I. Chaiken, 1970, Journal of Biological Chemistry.

Purification and properties of semisynthetic staphylococcal nuclease-T'.

I. Chaiken, Irwin M. Chaiken, 1971, The Journal of biological chemistry.

Carbon-13 Fourier transform nuclear magnetic resonance studies of peptides.

I. Chaiken, J. Cohen, M. Freedman, 1971, Biochemical and biophysical research communications.

Slow-dissociation effect of common signaling subunit beta c on IL5 and GM-CSF receptor assembly.

I. Chaiken, T. Ishino, M. Zaks-Zilberman, 2008, Cytokine.

Kinetic Interaction Analysis of Human Interleukin 5 Receptor α Mutants Reveals a Unique Binding Topology and Charge Distribution for Cytokine Recognition*

Gianfranco Pasut, I. Chaiken, G. Pasut, 2004, Journal of Biological Chemistry.

Biosensor analysis of dynamics of interleukin 5 receptor subunit βc interaction with IL5:IL5Rα complexes

Emma Evergren, Gabriela Canziani, I. Chaiken, 2002 .

Interdomain communication of T-cell CD4 studied by absorbance and fluorescence difference spectroscopy measurements of urea-induced unfolding.

I. Chaiken, D. Myszka, R. Sweet, 1995, Biochemistry.

The effects of ligands on enzymic carboxyl-methylation of neurophysins.

J. Axelrod, I. Chaiken, E. Diliberto, 1976, Biochemical and biophysical research communications.

Peptide triazole inactivators of HIV-1: how do they work and what is their potential?

I. Chaiken, Adel A Rashad, 2015, Future medicinal chemistry.

Roles of variable linker length in dual acting virucidal entry inhibitors on HIV‐1 potency via on‐the‐fly free energy molecular simulations

I. Chaiken, C. Abrams, B. Parajuli, 2020, Protein science : a publication of the Protein Society.

Roles of conserved tryptophans in trimerization of HIV‐1 membrane‐proximal external regions: Implications for virucidal design via alchemical free‐energy molecular simulations

I. Chaiken, C. Abrams, B. Parajuli, 2018, Proteins.

Sequence modeling using semisynthetic ribonuclease S.

I. Chaiken, A. Komoriya, 1982, The Journal of biological chemistry.

Antisense peptide recognition of sense peptides: sequence simplification and evaluation of forces underlying the interaction.

Y. Shai, I. Chaiken, T. Brunck, 1989, Biochemistry.

Structure-Based Design, Synthesis and Validation of CD4-Mimetic Small Molecule Inhibitors of HIV-1 Entry: Conversion of a Viral Entry Agonist to an Antagonist

Peter D. Kwong, Wayne A. Hendrickson, Joel R. Courter, 2014, Accounts of chemical research.

Short Communication: Inhibition of DC-SIGN-Mediated HIV-1 Infection by Complementary Actions of Dendritic Cell Receptor Antagonists and Env-Targeting Virus Inactivators.

I. Chaiken, Adel A Rashad, M. Hutchinson, 2015, AIDS research and human retroviruses.

The Active Core in a Triazole Peptide Dual‐Site Antagonist of HIV‐1 gp120

Judith M. LaLonde, E. Freire, I. Chaiken, 2010, ChemMedChem.

Recognition of HIV‐inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664

John P. Moore, I. Chaiken, C. Abrams, 2017, Proteins.

Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter.

I. Chaiken, Adel A Rashad, Irwin Chaiken, 2015, Journal of medicinal chemistry.

Kinetic and structural analysis of mutant CD4 receptors that are defective in HIV gp120 binding.

W. Hendrickson, I. Chaiken, D. Myszka, 1996, Proceedings of the National Academy of Sciences of the United States of America.

New Opportunities for Using Immobilized Ligands to Characterize Macromolecular Recognition and Design Recognition Molecules

I. Chaiken, D. Myszka, T. Morton, 1996 .

Beta-turn Phe in HIV-1 Env binding site of CD4 and CD4 mimetic miniprotein enhances Env binding affinity but is not required for activation of co-receptor/17b site.

Joseph Sodroski, J. Sodroski, E. Freire, 2002, Biochemistry.

Recognition properties of antisense peptides to Arg8-vasopressin/bovine neurophysin II biosynthetic precursor sequences.

M. Zamai, I. Chaiken, G. Fassina, 1989, Biochemistry.

Mimicry and antagonism in biotechnology drug discovery: Recognition peptides in protein scaffolds

I. Chaiken, D. O'Shannessy, M. Brigham-Burke, 1991 .

Quantitative affinity high-performance liquid chromatography of neuroendocrine polypeptides using porous and non-porous glass derivatives.

I. Chaiken, H. Swaisgood, 1985, Journal of chromatography.

Use of Reverse-Phase High-Performance Liquid Chromatography in Structural Studies of Neurophysins, Photolabeled Derivatives, and Biosynthetic Precursors1

H. Gainer, M. Brownstein, I. Chaiken, 1983 .

Molecular properties of the oxytocin/bovine neurophysin biosynthetic precursor. Studies using a semisynthetic precursor.

I. Chaiken, T. Kanmera, 1985, The Journal of biological chemistry.

Onset of neurophysin self‐association upon neurophysin/neuropeptide hormone precursor biosynthesis

H. Gainer, M. Brownstein, I. Chaiken, 1983, FEBS letters.

CHAPTER 9 – Structural Bases of Biological Function: From Nucleases to Neurophysins

I. Chaiken, 1984 .

Functional purification of synthetic proteins and protein fragments.

I. Chaiken, 1974, Methods in Enzymology.

Structure-function relationships at the active site of nuclease-T'.

C. Anfinsen, I. Chaiken, G. Sánchez, 1973, The Journal of biological chemistry.

Chemical studies of structural features in staphylococcal nuclease-T'.

I. Chaiken, 1972, The Journal of biological chemistry.

Solic phase synthetic study of the active site region of staphylococcal nuclease-T'.

C. Anfinsen, I. Chaiken, 1971, The Journal of biological chemistry.

Binding interactions of human interleukin 5 with its receptor alpha subunit. Large scale production, structural, and functional studies of Drosophila-expressed recombinant proteins.

S. Carr, M. Doyle, Baoguang Zhao, 1995, The Journal of biological chemistry.

Analysis of Ligand-Macromolecule Interactions by Quantitative Affinity Chromatography

I. Chaiken, 1978 .

Immunological and chemical identification of a neurophysin-containing protein coded by messenger RNA from bovine hypothalamus.

L. Giudice, I. Chaiken, 1979, Proceedings of the National Academy of Sciences of the United States of America.

Multisite mutagenesis of interleukin 5 differentiates sites for receptor recognition and receptor activation.

I. Chaiken, S. -. Wu, C. Plugariu, 2000, Biochemistry.

Interactions and uses of antisense peptides in affinity technology.

I. Chaiken, 1992, Journal of chromatography.

Trypsin-catalyzed conversion of staphylococcal nuclease-T fragment complexes to covalent forms.

I. Chaiken, G. Homandberg, 1980, The Journal of biological chemistry.

Pituitary enzyme conversion of putative synthetic oxytocin precursor intermediates.

I. Chaiken, T. Kanmera, 1985, The Journal of biological chemistry.

Photoaffinity labeling of the hormone binding site of neurophysin.

I. Chaiken, W. McCormick, D. M. Abercrombie, 1982, The Journal of biological chemistry.

Synthetic Peptides and the Design of Peptide and Protein Recognition Surfaces

Y. Shai, I. Chaiken, G. Fassina, 1987 .