A. Smith

发表

CD8 memory T cells have a bioenergetic advantage that underlies their rapid recall ability

B. Faubert, Russell G. Jones, G. V. D. van der Windt, 2013, Proceedings of the National Academy of Sciences.

Validated Models of Immune Response to Virus Infection.

A. Smith, Amber M Smith, 2018, Current opinion in systems biology.

An accurate two-phase approximate solution to an acute viral infection model

Frederick R Adler, Alan S Perelson, A. Perelson, 2010, Journal of mathematical biology.

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

Maxim N. Artyomov, Russell G. Jones, G. V. D. van der Windt, 2014, Nature Immunology.

Mathematical model of a three-stage innate immune response to a pneumococcal lung infection.

J. McCullers, A. Smith, F. Adler, 2011, Journal of theoretical biology.

Kinetics of Coinfection with Influenza A Virus and Streptococcus pneumoniae

A. Perelson, R. Gutenkunst, R. Ribeiro, 2013, PLoS pathogens.

Host‐pathogen kinetics during influenza infection and coinfection: insights from predictive modeling

A. Smith, 2018, Immunological reviews.

IL-4–Secreting Secondary T Follicular Helper (Tfh) Cells Arise from Memory T Cells, Not Persisting Tfh Cells, through a B Cell–Dependent Mechanism

B. Everts, A. Smith, E. Pearce, 2015, The Journal of Immunology.

Dynamically linking influenza virus infection kinetics, lung injury, inflammation, and disease severity

David J. Moquin, Amanda P. Smith, P. Thomas, 2019, bioRxiv.

The Nonlinear Relations that Predict Influenza Viral Dynamics, CD8+ T cell-Mediated Clearance, Lung Pathology, and Disease Severity

David J. Moquin, Amanda P. Smith, A. Smith, 2019 .

A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice

A. Smith, Teresa L. Ai, M. Baldridge, 2018, Journal of Virology.

COVID-19 virtual patient cohort reveals immune mechanisms driving disease outcomes

Amanda P. Smith, A. Smith, P. Morel, 2021, bioRxiv.

mTORC 2-IRF 4 mediated metabolic reprograming is essential for macrophage alternative activation

Pearce, M. Colonna, B. Everts, 2017 .

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.

M. Colonna, B. Everts, S. C. Huang, 2016, Immunity.

A Distal Enhancer in Il12b Is the Target of Transcriptional Repression by the STAT3 Pathway and Requires the Basic Leucine Zipper (B-ZIP) Protein NFIL3*

A. Smith, S. Smale, S. Schultz-Cherry, 2011, The Journal of Biological Chemistry.

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

D. Green, J. Opferman, A. Smith, 2014, Immunity.

Influenza Virus Infection Model With Density Dependence Supports Biphasic Viral Decay

David J. Moquin, Amanda P. Smith, A. Smith, 2018, bioRxiv.

Modulation of adaptive immunity by different adjuvant-antigen combinations in mice lacking Nod2.

A. Smith, K. E. El Kasmi, P. Murray, 2008, Vaccine.

TNF Counterbalances the Emergence of M2 Tumor Macrophages.

M. Roussel, D. Kawauchi, A. Smith, 2015, Cell reports.

TNF Counterbalances the Emergence of M 2 Tumor Macrophages Graphical Abstract Highlights

M. Roussel, D. Kawauchi, A. Smith, 2022 .

Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears Graphical Abstract Highlights

Justin M. Richner, G. Ebel, M. Diamond, 2018 .

Cell-intrinsic lysosomal lipolysis is essential for macrophage alternative activation

Maxim N. Artyomov, D. O’Sullivan, B. Everts, 2014, Nature Immunology.

mature neutrophils STAT3 governs distinct pathways in emergency granulopoiesis and

M. Goldsmith, D. Link, A. Smith, 2013 .

Leveraging Computational Modeling to Understand Infectious Diseases

A. Smith, Rosemary A Aogo, A. Jenner, 2020, Current Pathobiology Reports.

Stress Kinase GCN2 Controls the Proliferative Fitness and Trafficking of Cytotoxic T Cells Independent of Environmental Amino Acid Sensing.

P. Thomas, A. Smith, P. Murray, 2016, Cell reports.

Erratum: Memory CD8 + T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development (Immunity (2014) 41(1) (75–88), (S1074761314002246) (10.1016/j.immuni.2014.06.005))

M. Birnbaum, D. O’Sullivan, S. C. Huang, 2018 .

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

K. Murphy, B. Everts, S. C. Huang, 2016, The Journal of experimental medicine.

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

A. Smith, T. Wynn, K. E. El Kasmi, 2009, PLoS pathogens.

General Nature of the STAT3-Activated Anti-Inflammatory Response1

W. Alexander, D. Hilton, A. Smith, 2006, The Journal of Immunology.

Role of Arginase 1 from Myeloid Cells in Th2-Dominated Lung Inflammation

A. Smith, T. Wynn, K. E. El Kasmi, 2013, PloS one.

Memory CD8+ T Cells Use Cell-Intrinsic Lipolysis to Support the Metabolic Programming Necessary for Development.

M. Birnbaum, G. V. D. van der Windt, D. O’Sullivan, 2018, Immunity.

Regulation of the Development of the Hepatic B Cell Compartment during Schistosoma mansoni Infection

B. Everts, A. Smith, E. Pearce, 2013, The Journal of Immunology.

Infection mansoni Schistosoma B Cell Compartment during Regulation of the Development of the Hepatic

B. Everts, A. Smith, E. Pearce, 2013 .

Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.

J. McCullers, A. Smith, 2013, Virus research.

Time to revisit the endpoint dilution assay and to replace the TCID50 as a measure of a virus sample’s infection concentration

Amanda P. Smith, C. Beauchemin, A. Smith, 2021, PLoS Comput. Biol..

Gestational Stage and IFN-λ Signaling Regulate ZIKV Infection In Utero.

M. Diamond, A. Smith, C. Coyne, 2017, Cell host & microbe.

Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia.

Kelli L Boyd, J. Yewdell, J. Bennink, 2007, Cell host & microbe.

TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.

A. Smith, I. Wicks, S. Masters, 2020, Cell reports.

Therapy with CTLA4-Ig and an antiviral monoclonal antibody controls chikungunya virus arthritis

Justin M. Richner, M. Diamond, J. Crowe, 2017, Science Translational Medicine.

COVID-19 virtual patient cohort suggests immune mechanisms driving disease outcomes

Amanda P. Smith, A. Smith, P. Morel, 2021, PLoS pathogens.

Modeling the viral dynamics of influenza A virus infection.

Ruy M Ribeiro, R. Ribeiro, A. Smith, 2010, Critical reviews in immunology.

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal Demise

M. Diamond, R. Klein, A. Smith, 2016, Cell.

A Mouse Model of Zika Virus Pathogenesis.

M. Diamond, A. Smith, Helen M. Lazear, 2016, Cell host & microbe.

Cutting Edge: A Transcriptional Repressor and Corepressor Induced by the STAT3-Regulated Anti-Inflammatory Signaling Pathway1

Peter J. Murray, A. Smith, G. Neale, 2007, The Journal of Immunology.

Memory CD8(+) T cells use cell-intrinsic lipolysis to support the metabolic programming necessary for development.

M. Birnbaum, G. V. D. van der Windt, S. C. Huang, 2014, Immunity.

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

G. Kaplan, A. Smith, G. Neale, 2010, Science Signaling.

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

G. Kaplan, A. Smith, T. Wynn, 2008, Nature Immunology.

The TLR2‐MyD88‐NOD2‐RIPK2 signalling axis regulates a balanced pro‐inflammatory and IL‐10‐mediated anti‐inflammatory cytokine response to Gram‐positive cell walls

D. Finkelstein, A. Smith, G. Núñez, 2008, Cellular microbiology.

STAT 3-Regulated Anti-Inflammatory and Corepressor Induced by the Cutting Edge : A Transcriptional Repressor

A. Smith, G. Neale, B. Foxwell, 2007 .

Ly6Chi Monocyte Recruitment Is Responsible for Th2 Associated Host-Protective Macrophage Accumulation in Liver Inflammation due to Schistosomiasis

B. Everts, S. C. Huang, A. Smith, 2014, PLoS pathogens.

Effect of 1918 PB1-F2 Expression on Influenza A Virus Infection Kinetics

Alan S. Perelson, Amber M. Smith, Frederick R. Adler, 2011, PLoS Comput. Biol..

Dynamic Pneumococcal Genetic Adaptations Support Bacterial Growth and Inflammation during Coinfection with Influenza

Amanda P. Smith, J. McCullers, A. Smith, 2019, bioRxiv.

Extracellular Vesicles in Viral Replication and Pathogenesis and Their Potential Role in Therapeutic Intervention

A. Smith, Santosh Kumar, Sunitha Kodidela, 2020, Viruses.

STAT3 governs distinct pathways in emergency granulopoiesis and mature neutrophils.

M. Goldsmith, D. Link, A. D. Panopoulos, 2006, Blood.

Safety, tolerability, pharmacokinetics, and antimalarial efficacy of a novel Plasmodium falciparum ATP4 inhibitor SJ733: a first-in-human and induced blood-stage malaria phase 1a/b trial.

J. McCarthy, R. Guy, F. Gusovsky, 2020, The Lancet. Infectious diseases.

Time-Dependent Increase in Susceptibility and Severity of Secondary Bacterial Infection during SARS-CoV-2 Infection

Amanda P. Smith, A. Smith, P. Vogel, 2022, bioRxiv.

Influenza A virus infection kinetics: quantitative data and models

A. Perelson, A. Smith, Amber M. Smith, 2011, Wiley interdisciplinary reviews. Systems biology and medicine.

M. Diamond, A. Smith, C. Coyne, 2018, Science Translational Medicine.

Sustained generation of nitric oxide and control of mycobacterial infection requires argininosuccinate synthase 1.

C. Rock, A. Smith, T. Decker, 2012, Cell host & microbe.

Type 1 Interferons Induce Changes in Core Metabolism that Are Critical for Immune Function.

Maxim N. Artyomov, Qiongyu Chen, B. Everts, 2016, Immunity.

Enhanced IL-1β production is mediated by a TLR2-MYD88-NLRP3 signaling axis during coinfection with influenza A virus and Streptococcus pneumoniae

J. McCullers, A. Smith, T. Kanneganti, 2019, PloS one.

STING-associated vasculopathy develops independently of IRF3 in mice

Nan Yan, A. Smith, Teresa L. Ai, 2017, The Journal of experimental medicine.

Secondary Bacterial Infections in Influenza Virus Infection Pathogenesis

J. McCullers, A. Smith, 2014, Current topics in microbiology and immunology.

The Unexpected Impact of Vaccines on Secondary Bacterial Infections Following Influenza.

A. Smith, V. Huber, Victor C. Huber, 2017, Viral immunology.

T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions*

C. Rock, A. Smith, G. Neale, 2016, The Journal of Biological Chemistry.

TBK1 and IKK epsilon Act Redundantly to Mediate STING-Induced NF-kappa B Responses in Myeloid Cells

A. Smith, I. Wicks, S. Masters, 2020 .

A Critical, Nonlinear Threshold Dictates Bacterial Invasion and Initial Kinetics During Influenza

Amanda P. Smith, A. Smith, 2016, Scientific Reports.

Iterative community-driven development of a SARS-CoV-2 tissue simulator

Yafei Wang, Bing Liu, James A. Glazier, 2020, bioRxiv.

Zika Virus Infection during Pregnancy in Mice Causes Placental Damage and Fetal

M. Diamond, R. Klein, A. Smith, 2016 .

Quantifying dose-, strain-, and tissue-specific kinetics of parainfluenza virus infection

A. Smith, C. Russell, Lubna Pinky, 2021, PLoS Comput. Biol..

Quantifying the therapeutic requirements and potential for combination therapy to prevent bacterial coinfection during influenza

A. Smith, 2016, Journal of Pharmacokinetics and Pharmacodynamics.

Cell Host & Microbe Resource A Mouse Model of Zika Virus Pathogenesis

M. Diamond, A. Smith, Helen M. Lazear, 2016 .

Cutting edge: a transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway

A. Smith, G. Neale, K. E. El Kasmi, 2008, The Journal of Immunology.

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12

K. Murphy, B. Everts, S. C. Huang, 2016, The Journal of experimental medicine.

Metabolic Reprogramming Mediated by the mTORC2-IRF4 Signaling Axis Is Essential for Macrophage Alternative Activation.

M. Colonna, B. Everts, S. C. Huang, 2016, Immunity.

Zika Virus Infection in Mice Causes Panuveitis with Shedding of Virus in Tears.

Justin M. Richner, G. Ebel, M. Diamond, 2016, Cell reports.

Myeloid-derived suppressor activity is mediated by monocytic lineages maintained by continuous inhibition of extrinsic and intrinsic death pathways.

D. Green, J. Opferman, A. Smith, 2014, Immunity.

Molecular signatures of virulence in the PB1-F2 proteins of H5N1 influenza viruses.

J. McCullers, A. Smith, 2013, Virus research.

Crystal Structures Capture Three States in the Catalytic Cycle of a Pyridoxal Phosphate (PLP) Synthase*♦

A. Smith, Janet L. Smith, E. Harms, 2015, The Journal of Biological Chemistry.