J. Saven

发表

Theoretical and computational protein design.

Christopher M. MacDermaid, I. Samish, Christopher M MacDermaid, 2011, Annual review of physical chemistry.

An induced fit mechanism regulates p53 DNA binding kinetics to confer sequence specificity

Thomas J Petty, J. Saven, S. Emamzadah, 2011, The EMBO journal.

Local conformational signals and the statistical thermodynamics of collapsed helical proteins.

P. Wolynes, J. Saven, 1996, Journal of molecular biology.

Statistical theory for protein ensembles with designed energy landscapes.

Jinming Zou, Jeffery G Saven, Parbati Biswas, 2005, The Journal of chemical physics.

Evolutionary constraints on structural similarity in orthologs and paralogs

A. Sali, P. Babbitt, F. Chen, 2009, Protein science : a publication of the Protein Society.

Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor.

W. DeGrado, J. Saven, Vikas Nanda, 2005, Journal of the American Chemical Society.

Nanotubes, Plates, and Needles: Pathway-Dependent Self-Assembly of Computationally Designed Peptides.

J. Saven, D. Pochan, K. Kiick, 2018, Biomacromolecules.

Computational design of a protein crystal

Christopher M. MacDermaid, W. DeGrado, C. Lanci, 2012, Proceedings of the National Academy of Sciences.

A focused antibody library for selecting scFvs expressed at high levels in the cytoplasm

N. Bec, C. Larroque, P. Martineau, 2007, BMC biotechnology.

Computational Design of Four‐Helix Bundle Proteins That Bind Nonbiological Cofactors

A. Lehmann, J. Saven, 2008, Biotechnology progress.

Statistical theory of combinatorial libraries of folding proteins: energetic discrimination of a target structure.

J G Saven, J. Saven, J. Zou, 2000, Journal of molecular biology.

Computational Design of Membrane Proteins

J. M. Perez-Aguilar, J. Saven, 2012, Structure.

Computational Protein Design

J. Saven, 2011 .

Chapter 18 Computationally Assisted Protein Design

J. Saven, Sheldon Park, 2005 .

Computational methods for protein design and protein sequence variability: Biased Monte Carlo and replica exchange

Jeffery G. Saven, J. Saven, Xi Yang, 2005 .

Computational design and characterization of a monomeric helical dinuclear metalloprotein.

Hidetoshi Kono, Jeffery G Saven, Wei Wang, 2003, Journal of molecular biology.

Combinatorial protein design.

Jeffery G Saven, J. Saven, 2002, Current opinion in structural biology.

Designing gene libraries from protein profiles for combinatorial protein experiments.

Wei Wang, Jeffery G Saven, J. Saven, 2002, Nucleic acids research.

Advances in computational protein design.

Sheldon Park, Jeffery G Saven, J. Saven, 2004, Current opinion in structural biology.

Binding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking Recommended Citation Binding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking

J. M. Perez-Aguilar, J. Saven, Renyu Liu, 2022 .

NMR structure and dynamics of a designed water-soluble transmembrane domain of nicotinic acetylcholine receptor.

Jing He, Pei Tang, Wei Wang, 2012, Biochimica et biophysica acta.

De Novo Computational Protein Design

J. Saven, 2013 .

Polyelectrolyte character of rigid rod peptide bundlemer chains constructed via hierarchical self-assembly.

J. Saven, Christopher J. Kloxin, D. Pochan, 2019, Soft matter.

Novel variants of engineered water soluble mu opioid receptors with extensive mutations and removal of cysteines

B. Selling, J. M. Perez-Aguilar, J. Saven, 2021, Proteins.

Characterization of an engineered water-soluble variant of the full-length human mu opioid receptor

J. M. Perez-Aguilar, J. Saven, Jinglei Ping, 2020, Journal of biomolecular structure & dynamics.

Molecular recognition of ketamine by a subset of olfactory G protein–coupled receptors

R. Eckenhoff, J. M. Perez-Aguilar, J. Saven, 2015, Science Signaling.

Photoinduced Electron Transfer Elicits a Change in the Static Dielectric Constant of a de Novo Designed Protein.

C. Lanci, D. Beratan, J. M. Perez-Aguilar, 2016, Journal of the American Chemical Society.

Highly tunable photoluminescent properties of amphiphilic conjugated block copolymers.

So-Jung Park, J. Saven, Sangjin Park, 2010, Journal of the American Chemical Society.

Computational Protein Design

J. Saven, 2011 .

Human μ Opioid Receptor Models with Evaluation of the Accuracy Using the Crystal Structure of the Murine μ Opioid Receptor

J. M. Perez-Aguilar, J. Saven, Renyu Liu, 2012, Journal of anesthesia & clinical research.

Helical wrapping of single-walled carbon nanotubes by water soluble poly(p-phenyleneethynylene).

D. Bonnell, J. Saven, S. Kim, 2009, Nano letters.

Nanofibers Produced by Electrospinning of Ultrarigid Polymer Rods Made from Designed Peptide Bundlemers.

J. Saven, Christopher J. Kloxin, D. Pochan, 2021, ACS applied materials & interfaces.

Quantifying the effect of ionic screening with protein-decorated graphene transistors.

A. T. Johnson, J. Saven, Jinglei Ping, 2017, Biosensors & bioelectronics.

Water Soluble G-protein Coupled Receptor Enabled Biosensors

A. T. Johnson, J. Saven, Renyu Liu, 2019, Translational perioperative and pain medicine.

A protein–protein host–guest complex: Thermostable ferritin encapsulating positively supercharged green fluorescent protein

J. Saven, J. Villegas, I. Dmochowski, 2018, Protein science : a publication of the Protein Society.

Characterization of the cofactor-induced folding mechanism of a zinc-binding peptide using computationally designed mutants.

J. Saven, F. Gai, Jia Tang, 2009, Journal of molecular biology.

Computationally designed peptides for self-assembly of nanostructured lattices

Jeffery G. Saven, Huixi Violet Zhang, Kristi L. Kiick, 2016, Science Advances.

Solvophobically driven folding of nonbiological oligomers.

J S Moore, P G Wolynes, J G Saven, 1997, Science.

Multiple hindered rotators in a gyroscope-inspired tribenzylamine hemicryptophane.

J. M. Perez-Aguilar, J. Saven, I. Dmochowski, 2011, Journal of Organic Chemistry.

Cooperative Conformational Transitions in Phenylene Ethynylene Oligomers: Chain-Length Dependence

Jeffery G. Saven, Peter G. Wolynes, P. Wolynes, 1999 .

Single-handed helical wrapping of single-walled carbon nanotubes by chiral, ionic, semiconducting polymers.

J. Saven, P. Deria, M. Therien, 2013, Journal of the American Chemical Society.

Computational protein design and discovery

Xi Yang, Jeffery G. Saven, Wei Wang, 2004 .

Simulation Studies of a Helical m-Phenylene Ethynylene Foldamer

J. Saven, One-Sun Lee, 2004 .

Peptide Design and Self-assembly into Targeted Nanostructure and Functional Materials.

J. Saven, Christopher J. Kloxin, D. Pochan, 2021, Chemical reviews.

Scalable Production of Molybdenum Disulfide Based Biosensors.

Jeffery G Saven, Jin Xi, Renyu Liu, 2016, ACS nano.

Ultrafast folding of a computationally designed Trp-cage mutant: Trp2-cage.

Jeffery G Saven, Feng Gai, J. Saven, 2006, The journal of physical chemistry. B.

Statistical theory for protein combinatorial libraries. Packing interactions, backbone flexibility, and the sequence variability of a main-chain structure.

J G Saven, H. Kono, J. Saven, 2001, Journal of molecular biology.

A molecular theory of the line shape : inhomogeneous and homogeneous electronic spectra of dilute chromophores in nonpolar fluids

J. Saven, J. Skinner, 1993 .

Molecular theory of electronic spectroscopy in nonpolar fluids: Ultrafast solvation dynamics and absorption and emission line shapes

M. D. Stephens, J. Saven, J. Skinner, 1997 .

Thermophilic Ferritin 24mer Assembly and Nanoparticle Encapsulation Modulated by Interdimer Electrostatic Repulsion.

J. Saven, I. Dmochowski, K. Pulsipher, 2017, Biochemistry.

Intramolecular structure and dynamics in computationally designed peptide-based polymers displaying tunable chain stiffness

A. Faraone, J. Saven, Christopher J. Kloxin, 2021, Physical Review Materials.

Statistical and molecular dynamics studies of buried waters in globular proteins

Sheldon Park, Jeffery G Saven, J. Saven, 2005, Proteins.

pH Sensing Properties of Flexible, Bias-Free Graphene Microelectrodes in Complex Fluids: From Phosphate Buffer Solution to Human Serum.

J. Saven, A. T. Johnson, Zhaoli Gao, 2017, Small.

Structural-functional analysis of engineered protein-nanoparticle assemblies using graphene microelectrodes† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c7sc01565h Click here for additional data file.

A. T. Johnson, J. Saven, I. Dmochowski, 2017, Chemical science.

Classical and quantum continuum percolation with hard core interactions

J. Saven, J. Skinner, J. R. Wright, 1991 .

Molecular interactions between general anesthetics and the 5HT2B receptor

Xi-Ping Huang, B. Roth, J. Saven, 2015, Journal of biomolecular structure & dynamics.

De novo design of a redox-active minimal rubredoxin mimic.

Vikas Nanda, Hidetoshi Kono, Jeffery G Saven, 2005, Journal of the American Chemical Society.

Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization.

J. Saven, I. Dmochowski, Rui Guo, 2021, Biochemistry.

Modulating the DNA affinity of Elk-1 with computationally selected mutations.

J. Saven, Sheldon Park, E. Boder, 2005, Journal of molecular biology.

Computational Design of Single-Peptide Nanocages with Nanoparticle Templating

J. Saven, D. Pochan, N. Teramoto, 2022, Molecules.

Kinetics of protein folding: The dynamics of globally connected rough energy landscapes with biases

Jeffery G. Saven, Peter G. Wolynes, P. Wolynes, 1994 .

Simulation of pH‐dependent edge strand rearrangement in human β‐2 microglobulin

J. Saven, Sheldon Park, 2006 .

Simulation of pH-dependent edge strand rearrangement in human beta-2 microglobulin.

J. Saven, Sheldon Park, 2006, Protein science : a publication of the Protein Society.

Scalable Production of Highly Sensitive Nanosensors Based on Graphene Functionalized with a Designed G Protein-Coupled Receptor

Jeffery G. Saven, Yung Woo Park, Alexander Crook, 2014, Nano letters.

The C-Terminus of the mu Opioid Receptor Is Critical in G-Protein Interaction as Demonstrated by a Novel Graphene Biosensor

B. Selling, A. T. Johnson, J. M. Perez-Aguilar, 2021, IEEE Sensors Journal.

Computational de novo design and characterization of a protein that selectively binds a highly hyperpolarizable abiological chromophore.

Inge Asselberghs, Koen Clays, Jeffery G Saven, 2013, Journal of the American Chemical Society.

Computational design and elaboration of a de novo heterotetrameric alpha-helical protein that selectively binds an emissive abiological (porphinato)zinc chromophore.

Jeffery G Saven, W. DeGrado, A. Lehmann, 2010, Journal of the American Chemical Society.

Opioid binding sites in human serum albumin.

J. M. Perez-Aguilar, J. Saven, Renyu Liu, 2012, Anesthesia and analgesia.

Molecular Dynamics Simulation of WSK-3, a Computationally Designed, Water-Soluble Variant of the Integral Membrane Protein KcsA.

One-Sun Lee, Jonathan Bronson, Jeffery G Saven, 2006, Biophysical journal.

Computational Protein Design to Re-engineer Stromal Cell-derived Factor-1α (sdf) Generates an Effective and Translatable Angiogenic Polypeptide Analog Recommended Citation Computational Protein Design to Re-engineer Stromal Cell-derived Factor-1α (sdf) Generates an Effective and Translatable Angioge

J. R. Fitzpatrick, J. M. Perez-Aguilar, J. Saven, 2022 .

Polymers with controlled assembly and rigidity made with click-functional peptide bundles

J. Caplan, J. Saven, Christopher J. Kloxin, 2019, Nature.

Using alpha-helical coiled-coils to design nanostructured metalloporphyrin arrays.

Alessandro Senes, Vikas Nanda, Jeffery G Saven, 2008, Journal of the American Chemical Society.

Directing noble metal ion chemistry within a designed ferritin protein.

Seung-Gu Kang, Jeffery G Saven, Joe Swift, 2008, Biochemistry.

Computational design and selections for an engineered, thermostable terpene synthase

Jonathan Bronson, Jeffery G Saven, Gregory A Weiss, 2011, Protein science : a publication of the Protein Society.

Origins of the helical wrapping of phenyleneethynylene polymers about single-walled carbon nanotubes.

Christopher M MacDermaid, J. Saven, P. Deria, 2013, The journal of physical chemistry. B.

Colloid-like solution behavior of computationally designed coiled coil bundlemers.

A. Faraone, J. Saven, J. Fagan, 2021, Journal of colloid and interface science.

Recombinant expression of computationally designed peptide-bundlemers in Escherichia coli.

Z. Kelman, J. Saven, Christopher J. Kloxin, 2021, Journal of biotechnology.

Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles.

J. Saven, J. Fagan, D. Pochan, 2018, Soft matter.

Fabrication of One- and Two-Dimensional Gold Nanoparticle Arrays on Computationally Designed Self-Assembled Peptide Templates

J. Saven, D. Pochan, K. Kiick, 2018, Chemistry of Materials.

Transition from disordered aggregates to ordered lattices: kinetic control of the assembly of a computationally designed peptide.

J. Saven, D. Pochan, K. Kiick, 2017, Organic & biomolecular chemistry.

A Surface Hopping View of Electrochemistry: Non-Equilibrium Electronic Transport through an Ionic Solution with a Classical Master Equation

Joseph E. Subotnik, W. Ouyang, J. Saven, 2015 .

Limitations of yeast surface display in engineering proteins of high thermostability.

Xiaoran Fu Stowell, Sheldon Park, Jeffery G Saven, 2006, Protein engineering, design & selection : PEDS.

Improving target amino acid selectivity in a permissive aminoacyl tRNA synthetase through counter-selection.

J. Perona, J. Saven, C. Driggers, 2017, Organic & biomolecular chemistry.

Computational design of water-soluble analogues of the potassium channel KcsA

Jeffery G. Saven, Hidetoshi Kono, William F. DeGrado, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Progress in the development and application of computational methods for probabilistic protein design

Wei Wang, Jeffery G. Saven, Hidetoshi Kono, 2005, Comput. Chem. Eng..

Statistical Theory for Protein Combinatorial Libraries

H Kono, J G Saven, J Zou, 2001 .

Engineering complementary hydrophobic interactions to control β-hairpin peptide self-assembly, network branching, and hydrogel properties.

Christopher M. MacDermaid, Christopher M MacDermaid, J. Saven, 2014, Biomacromolecules.

Structural coupling between FKBP12 and buried water

J. Saven, Sheldon Park, G. V. Van Duyne, 2009, Proteins.

Identification of the Active Form of Endothelial Lipase, a Homodimer in a Head-to-Tail Conformation*

Thomas J Petty, D. Rader, J. Saven, 2009, The Journal of Biological Chemistry.

All-Electronic Quantification of Neuropeptide-Receptor Interaction Using a Bias-Free Functionalized Graphene Microelectrode.

J. Saven, A. T. Johnson, Jinglei Ping, 2018, ACS nano.

Guiding the search for a protein's maximum rate of folding

Jeffery G. Saven, Shoji Takada, Ting Wang, 2004 .

Computational protein design: structure, function and combinatorial diversity.

Jeffery G Saven, J. Saven, Seung-gu Kang, 2007, Current opinion in chemical biology.

Controlling Association and Separation of Gold Nanoparticles with Computationally Designed Zinc-Coordinating Proteins.

Christopher M. MacDermaid, So-Jung Park, C. Lanci, 2017, Journal of the American Chemical Society.

Magneto-structural relationships for radical cation and neutral pyridinophane structures with intrabridgehead nitrogen atoms. An integrated experimental and quantum mechanical study.

V. Barone, P. Cimino, J. Saven, 2009, Journal of Physical Chemistry B.

Computational protein design: engineering molecular diversity, nonnatural enzymes, nonbiological cofactor complexes, and membrane proteins.

Jeffery G Saven, J. Saven, 2011, Current opinion in chemical biology.

Observing Changes in the Structure and Oligomerization State of a Helical Protein Dimer Using Solid-State Nanopores.

C. Lanci, Gabriel Shemer, M. Drndić, 2015, ACS nano.

Computational Protein Design to Reengineer Stromal Cell–Derived Factor-1&agr; Generates an Effective and Translatable Angiogenic Polypeptide Analog

J. R. Fitzpatrick, J. M. Perez-Aguilar, J. Saven, 2011, Circulation.

Computational Protein Design to Re-Engineer Stromal Cell-Derived Computational Protein Design to Re-Engineer Stromal Cell-Derived Factor-1 α (SDF) Generates an Effective and Translatable Factor-1 (SDF) Generates an Effective and Translatable Angiogenic Polypeptide Analog Angiogenic Polypeptide Analo

J. R. Fitzpatrick, J. M. Perez-Aguilar, J. Saven, 2021 .

Computational Protein Design to Reengineer Stromal Cell-Derived Factor-1 alpha Generates an Effective and Translatable Angiogenic Polypeptide Analog

J. R. Fitzpatrick, J. M. Perez-Aguilar, J. Saven, 2022 .

Computational de novo design and characterization of a four-helix bundle protein that selectively binds a nonbiological cofactor.

Wei Wang, Jeffery G. Saven, Vikas Nanda, 2005, Journal of the American Chemical Society.

A Computationally Designed Water-Soluble Variant of a G-Protein-Coupled Receptor: The Human Mu Opioid Receptor

Jeffery G. Saven, Jin Xi, Renyu Liu, 2013, PloS one.

Design of functional ferritin-like proteins with hydrophobic cavities.

Xiaoran Fu Stowell, Jeffery G Saven, Joe Swift, 2006, Journal of the American Chemical Society.

Molecular Theory of Optical Absorption Lineshapes of Dilute Solutes in Liquids: A Probe of Solvent Dynamics

J. Saven, J. L. Skinner, 1994 .

Computational protein design: Advances in the design and redesign of biomolecular nanostructures.

Jeffery G Saven, J. Saven, 2010, Current opinion in colloid & interface science.

Characterization of the cofactor-induced folding mechanism of a zinc-binding peptide using computationally designed mutants.

J. Saven, F. Gai, Jia Tang, 2009, Journal of molecular biology.

STATISTICAL MECHANICS OF THE COMBINATORIAL SYNTHESIS AND ANALYSIS OF FOLDING MACROMOLECULES

Jeffery G. Saven, Peter G. Wolynes, P. Wolynes, 1997 .

Designing protein energy landscapes.

J G Saven, J. Saven, 2001, Chemical reviews.

Genetically Fused Resilin-like Polypeptide-Coiled Coil Bundlemer Conjugates Exhibit Tunable Multistimuli-Responsiveness and Undergo Nanofibrillar Assembly.

J. Saven, D. Pochan, K. Kiick, 2024, Biomacromolecules.

Highly tunable photoluminescent properties of amphiphilic conjugated block copolymers.

So-Jung Park, J. Saven, Sangjin Park, 2010, Journal of the American Chemical Society.

Dynamic Nanocrystal Superlattices with Thermally Triggerable Lubricating Ligands.

J. Saven, C. Kagan, Shengsong Yang, 2024, Journal of the American Chemical Society.

Using self-consistent fields to bias Monte Carlo methods with applications to designing and sampling protein sequences

Jinming Zou, Jeffery G. Saven, J. Saven, 2003 .

An interior water is essential for maintaining the structure of FKBP12

Sheldon Park, Szilvia Szép, Eric T. Boder, 2006 .

Binding Site and Affinity Prediction of General Anesthetics to Protein Targets Using Docking

J. M. Perez-Aguilar, J. Saven, Renyu Liu, 2012, Anesthesia and analgesia.