Hongbin Li

发表

Force-Clamp Spectroscopy Monitors the Folding Trajectory of a Single Protein

Julio M Fernandez, Hongbin Li, Julio M. Fernandez, 2004, Science.

The mechanical stability of ubiquitin is linkage dependent

Hui Lu, A. Oberhauser, Julio M Fernandez, 2003, Nature Structural Biology.

An ion signal responsive dynamic protein nano-spring constructed by high ordered host-guest recognition.

Hongbin Li, Chengye Si, Jiaxi Li, 2016, Chemical communications.

Mechanical unfolding intermediates in titin modules

Klaus Schulten, Andres F. Oberhauser, Hui Lu, 1999, Nature.

Designed biomaterials to mimic the mechanical properties of muscles

D. Dudek, Hongbin Li, J. Gosline, 2010, Nature.

A functional single-molecule binding assay via force spectroscopy

Hongbin Li, Yi Cao, M. Balamurali, 2007, Proceedings of the National Academy of Sciences.

Ultrafast folding kinetics and cooperativity of villin headpiece in single-molecule force spectroscopy

Matthias Rief, Benjamin Pelz, Johannes Stigler, 2013, Proceedings of the National Academy of Sciences.

Mapping the Broad Structural and Mechanical Properties of Amyloid Fibrils.

Jennifer M. Bui, J. Gsponer, Hongbin Li, 2017, Biophysical journal.

Slow Transition Path Times Reveal a Complex Folding Barrier in a Designed Protein

Hongbin Li, Johannes Stigler, B. Pelz, 2020, Frontiers in Chemistry.

Mechanics of Proteins and Tailored Mechanics of Engineered Proteins

Hongbin Li, A. Jollymore, Yi Cao, 2011 .

Single-molecule-level evidence for the osmophobic effect.

M. Brucale, B. Samorì, Hongbin Li, 2011, Angewandte Chemie.

Construction and characterization of kilobasepair densely labeled peptide-DNA.

E. Bromley, P. Curmi, N. R. Forde, 2014, Biomacromolecules.

Single-molecule Force Spectroscopy Reveals Engineered Metal Chelation Is A General Approach To Enhance Mechanical Stability Of Proteins

Hongbin Li, Yi Cao, Teri Yoo, 2009 .

Decorating a Blank Slate Protein Hydrogel: A General and Robust Approach for Functionalizing Protein Hydrogels.

Hongbin Li, Xiaoye Gao, Shanshan Lyu, 2017, Biomacromolecules.

Effects of Cysteine Proteases on the Structural and Mechanical Properties of Collagen Fibers*

Hongbin Li, Xin Du, D. Brömme, 2013, The Journal of Biological Chemistry.

Single-molecule force spectroscopy reveals a mechanically stable protein fold and the rational tuning of its mechanical stability

Hui Lu, Ognjen Perisic, Hui Lu, 2007, Proceedings of the National Academy of Sciences.

Single molecule force spectroscopy reveals critical roles of hydrophobic core packing in determining the mechanical stability of protein GB1.

Hongbin Li, Tianjia Bu, Hui-Chuan Wang, 2012, Langmuir : the ACS journal of surfaces and colloids.

Single molecule force spectroscopy reveals that iron is released from the active site of rubredoxin by a stochastic mechanism.

Hongbin Li, A. Mauk, Peng Zheng, 2013, Journal of the American Chemical Society.

Chemical, physical and morphological properties of bacterial biofilms affect survival of encased Campylobacter jejuni F38011 under aerobic stress.

Xiaonan Lu, Hongbin Li, S. Hatzikiriakos, 2015, International journal of food microbiology.

Hydrogels Constructed from Engineered Proteins.

Hongbin Li, Junqiu Liu, Na Kong, 2016, Small.

Protein Fragment Reconstitution as a Driving Force for Self‐Assembling Reversible Protein Hydrogels

Hongbin Li, Na Kong, 2015 .

Protein Hydrogels with Reversibly Patterned Multidimensional Fluorescent Images for Information Storage.

Hongbin Li, Tianyu Duan, Qingyuan Bian, 2022, Biomacromolecules.

Improved single molecule force spectroscopy using micromachined cantilevers.

T. Perkins, Hongbin Li, R. M. A. Sullan, 2014, ACS nano.

Templated folding of the RTX domain of the bacterial toxin adenylate cyclase revealed by single molecule force spectroscopy

Hongbin Li, Han Wang, Guojun Chen, 2022, Nature Communications.

Modelling the hydrolysis of iron-sulfur clusters.

Murilo H. Teixeira, Sofia R. G. Camilo, M. Field, 2019, Journal of chemical information and modeling.

A facile way to tune mechanical properties of artificial elastomeric proteins-based hydrogels.

Hongbin Li, Jie Fang, 2012, Langmuir : the ACS journal of surfaces and colloids.

Yellow fluorescent protein-based label-free tension sensors for monitoring integrin tension.

Hongbin Li, W. R. Algar, Michael V. Tran, 2020, Chemical communications.

Staphylokinase Displays Surprisingly Low Mechanical Stability.

Hongbin Li, Chengzhi He, 2017, Langmuir : the ACS journal of surfaces and colloids.

Mechanically tightening, untying and retying a protein trefoil knot by single-molecule force spectroscopy†

Hongbin Li, Han Wang, 2020, Chemical science.

Single molecule force spectroscopy reveals that a two-coordinate ferric site is critical for the folding of holo-rubredoxin.

Hongbin Li, Jiayu Li, 2020, Nanoscale.

Coil–Globule Transition of a Water-Soluble Polymer

Hongbin Li, Wenke Zhang, Huazhang Guo, 2022, Macromolecules.

Converting Muscle-mimetic Biomaterials to Cartilage-like Materials

Lan Li, Qing Jiang, Hongbin Li, 2021, bioRxiv.

Hydrogen bond strength modulates the mechanical strength of ferric-thiolate bonds in rubredoxin.

Hongbin Li, A. Mauk, Peng Zheng, 2012, Journal of the American Chemical Society.

Highly ordered protein nanorings designed by accurate control of glutathione S-transferase self-assembly.

Hongbin Li, Q. Luo, Junqiu Liu, 2013, Journal of the American Chemical Society.

Mechanically tightening a protein slipknot into a trefoil knot.

Guillaume Lamour, Chengzhi He, Hongbin Li, 2014, Journal of the American Chemical Society.

Quantifying thiol–gold interactions towards the efficient strength control

Hongbin Li, Wenke Zhang, Xun Li, 2014, Nature Communications.

Reverse engineering of the giant muscle protein titin

Wolfgang A. Linke, Andres F. Oberhauser, Piotr E. Marszalek, 2002, Nature.

Changes in Structural-Mechanical Properties and Degradability of Collagen during Aging-associated Modifications*

Guillaume Lamour, Frank Ko, Hongbin Li, 2015, The Journal of Biological Chemistry.

The force-driven conformations of heparin studied with single molecule force microscopy.

A. Oberhauser, Hongbin Li, P. Marszalek, 2003, Biophysical journal.

Direct measurements of the mechanical stability of zinc-thiolate bonds in rubredoxin by single-molecule atomic force microscopy.

Hongbin Li, Peng Zheng, 2011, Biophysical journal.

Engineering Protein Hydrogels Using SpyCatcher-SpyTag Chemistry.

Hongbin Li, Bin Xue, Xiaoye Gao, 2016, Biomacromolecules.

Light-Responsive Dynamic Protein Hydrogels Based on LOVTRAP.

Hongbin Li, Tianyu Duan, Qingyuan Bian, 2021, Langmuir : the ACS journal of surfaces and colloids.

An injectable self-healing protein hydrogel with multiple dissipation modes and tunable dynamic response.

Hongbin Li, Yi Cao, Wenxu Sun, 2019, Biomacromolecules.

Metal Chelation Dynamically Regulates the Mechanical Properties of Engineered Protein Hydrogels.

Hongbin Li, Qing Peng, Na Kong, 2017, ACS biomaterials science & engineering.

Fingerprinting polysaccharides with single-molecule atomic force microscopy

Hongbin Li, P. Marszalek, Julio M. Fernandez, 2001, Nature Biotechnology.

Engineering shape memory and morphing protein hydrogels based on protein unfolding and folding

Hongbin Li, Qingyuan Bian, Linglan Fu, 2022, Nature communications.

Single molecule force spectroscopy reveals the context dependent folding pathway of the C-terminal fragment of Top7

Hongbin Li, Yabin Guo, Han Wang, 2020, Chemical science.

Designing redox potential‐controlled protein switches based on mutually exclusive proteins

Hongbin Li, Qing Peng, Hui-Chuan Wang, 2012, Protein science : a publication of the Protein Society.

There Is Plenty of Room in The Folded Globular Proteins: Tandem Modular Elastomeric Proteins Offer New Opportunities in Engineering Protein‐Based Biomaterials

Hongbin Li, 2021, Advanced NanoBiomed Research.

Chair-boat transitions in single polysaccharide molecules observed with force-ramp AFM

A. Oberhauser, Hongbin Li, P. Marszalek, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Single-Molecule Force Spectroscopy Studies of Missense Titin Mutations That Are Likely Causing Cardiomyopathy

Hongbin Li, Jiacheng Zuo, Denghuang Zhan, 2021, Langmuir : the ACS journal of surfaces and colloids.

Toward Quantitative Prediction of the Mechanical Properties of Tandem Modular Elastomeric Protein-Based Hydrogels

Hongbin Li, Linglan Fu, 2020, Macromolecules.

Single molecule force spectroscopy reveals that the oxidation state of cobalt ions plays an important role in enhancing the mechanical stability of proteins.

Hongbin Li, Jiahao Xia, Jiacheng Zuo, 2019, Nanoscale.

Engineering protein polymers of ultrahigh molecular weight via supramolecular polymerization: towards mimicking the giant muscle protein titin† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02128k

Hongbin Li, Junqiu Liu, Jin Guo, 2019, Chemical science.

Single molecule force spectroscopy reveals that electrostatic interactions affect the mechanical stability of proteins.

Hongbin Li, S. Straus, Yi Cao, 2011, Biophysical journal.

Protein mechanics: from single molecules to functional biomaterials.

Hongbin Li, Yi Cao, Yi Cao, 2010, Accounts of chemical research.

Recombination of protein fragments: A promising approach toward engineering proteins with novel nanomechanical properties

Hongbin Li, M. Balamurali, D. Sharma, 2008, Protein science : a publication of the Protein Society.

‘Mechanical Engineering’ of Elastomeric Proteins: Toward Designing New Protein Building Blocks for Biomaterials

Hongbin Li, Hongbin Li, 2008 .

Single molecule force spectroscopy reveals engineered metal chelation is a general approach to enhance mechanical stability of proteins

Hongbin Li, Yi Cao, Yi Cao, 2008, Proceedings of the National Academy of Sciences.

Engineered elastomeric proteins with dual elasticity can be controlled by a molecular regulator.

Hongbin Li, Yi Cao, 2008, Nature nanotechnology.

Protein-protein interaction regulates proteins' mechanical stability.

Hongbin Li, Shulin Zhuang, Yi Cao, 2008, Journal of molecular biology.

Engineering proteins with tailored nanomechanical properties: a single molecule approach.

Hongbin Li, 2007, Organic & biomolecular chemistry.

Polyprotein of GB1 is an ideal artificial elastomeric protein.

Hongbin Li, Yi Cao, Yi Cao, 2007, Nature materials.

Engineering proteins with novel mechanical properties by recombination of protein fragments.

Hongbin Li, Yi Cao, D. Sharma, 2006, Angewandte Chemie.

Mechanical design of the first proximal Ig domain of human cardiac titin revealed by single molecule force spectroscopy.

Julio M Fernandez, Hongbin Li, Hongbin Li, 2003, Journal of molecular biology.

PEVK domain of titin: an entropic spring with actin-binding properties.

Mathias Gautel, Wolfgang A Linke, W. Linke, 2002, Journal of structural biology.

Multiple conformations of PEVK proteins detected by single-molecule techniques

A. Oberhauser, S. Redick, H. Erickson, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Point mutations alter the mechanical stability of immunoglobulin modules

Andres F. Oberhauser, Piotr E. Marszalek, Mariano Carrion-Vazquez, 2000, Nature Structural Biology.

Single Molecule Force Spectroscopy of Modular Proteins in the Nervous System

Hongbin Li, Thomas E Fisher, Mariano Carrion-Vazquez, 2000, Neuron.

The unfolding kinetics of ubiquitin captured with single-molecule force-clamp techniques.

Hongbin Li, M. Schlierf, Julio M. Fernandez, 2004, Proceedings of the National Academy of Sciences of the United States of America.

High intrinsic mechanical flexibility of mouse prion nanofibrils revealed by measurements of axial and radial Young's moduli.

Guillaume Lamour, Jörg Gsponer, J. Gsponer, 2014, ACS nano.

Phenotypic effects of Ehlers–Danlos syndrome‐associated mutation on the FnIII domain of tenascin‐X

Hongbin Li, Shulin Zhuang, A. Linhananta, 2010, Protein science : a publication of the Protein Society.

Tandem modular protein-based hydrogels constructed using a novel two-component approach.

Hongbin Li, Shanshan Lv, Yi Cao, 2012, Langmuir : the ACS journal of surfaces and colloids.

Contour length and refolding rate of a small protein controlled by engineered disulfide bonds.

Hector H. Huang, Hui Lu, Hongbin Li, 2007, Biophysical journal.

Harvesting Mechanical Work From Folding-Based Protein Engines: From Single-Molecule Mechanochemical Cycles to Macroscopic Devices

Hongbin Li, Han Wang, Linglan Fu, 2019, CCS Chemistry.

Atomic force microscopy reveals parallel mechanical unfolding pathways of T4 lysozyme: Evidence for a kinetic partitioning mechanism

Hongbin Li, Hongbin Li, Qing Peng, 2008, Proceedings of the National Academy of Sciences.

Easyworm: an open-source software tool to determine the mechanical properties of worm-like chains

Hongbin Li, Tuomas P. J. Knowles, Guillaume Lamour, 2014, Source Code for Biology and Medicine.

Response to Comment on "Force-Clamp Spectroscopy Monitors the Folding Trajectory of a Single Protein"

Hongbin Li, Julio M. Fernandez, J. Brujic, 2004, Science.

Highly covalent ferric-thiolate bonds exhibit surprisingly low mechanical stability.

Hongbin Li, Peng Zheng, 2011, Journal of the American Chemical Society.

Sub-angstrom conformational changes of a single molecule captured by AFM variance analysis.

Hongbin Li, Kirstin A. Walther, Julio M. Fernandez, 2006, Biophysical journal.

Decorating protein hydrogels reversibly enables dynamic presentation and release of functional protein ligands on protein hydrogels.

Hongbin Li, Junqiu Liu, Ruidi Wang, 2019, Chemical communications.

Modeling the Hydrolysis of Iron-Sulfur Clusters

Martin J. Field, Murilo H. Teixeira, Felipe Curtolo, 2019, J. Chem. Inf. Model..

Forced Protein Unfolding Leads to Highly Elastic and Tough Protein Hydrogels

D. Baker, M. Rief, N. Koga, 2013, Nature Communications.

Towards constructing extracellular matrix-mimetic hydrogels: an elastic hydrogel constructed from tandem modular proteins containing tenascin FnIII domains.

A. Bausch, Hongbin Li, Shanshan Lv, 2013, Acta biomaterialia.

Force-induced chemical reactions on the metal centre in a single metalloprotein molecule

M. Field, Hongbin Li, G. M. Arantes, 2015, Nature Communications.

Facile method of constructing polyproteins for single-molecule force spectroscopy studies.

Hongbin Li, Yi Cao, Peng Zheng, 2011, Langmuir : the ACS journal of surfaces and colloids.

In situ Phase Transition of Elastin-like Polypeptide Chains Regulates Thermo-Responsive Properties of Elastomeric Protein-Based Hydrogels.

Hongbin Li, Tianyu Duan, 2020, Biomacromolecules.

Single molecule force spectroscopy reveals a weakly populated microstate of the FnIII domains of tenascin.

Hongbin Li, Yi Cao, 2006, Journal of molecular biology.

Single molecule force spectroscopy: a new tool for bioinorganic chemistry.

Hongbin Li, Peng Zheng, 2018, Current opinion in chemical biology.

Configurational entropy modulates the mechanical stability of protein GB1.

Hongbin Li, Yi Cao, D. Sharma, 2008, Journal of molecular biology.

Measuring "unmeasurable" folding kinetics of proteins by single-molecule force spectroscopy.

Ashlee Jollymore, Hongbin Li, A. Jollymore, 2010, Journal of molecular biology.

Mechanical Anisotropy in GNNQQNY Amyloid Crystals.

Jennifer M. Bui, Hongbin Li, J. Gsponer, 2018, The journal of physical chemistry letters.

Direct monitoring of equilibrium protein folding-unfolding by atomic force microscopy: pushing the limit.

Hongbin Li, Adam Xiao, 2019, Chemical communications.

Mechanical Unfolding Pathway of the High-Potential Iron-Sulfur Protein Revealed by Single-Molecule Atomic Force Microscopy: Toward a General Unfolding Mechanism for Iron-sulfur Proteins.

Hongbin Li, Jiayu Li, 2018, The journal of physical chemistry. B.

Single molecule force spectroscopy reveals the molecular mechanical anisotropy of the FeS4 metal center in rubredoxin.

Hongbin Li, Yanyan Wang, Chih-Chung Chou, 2013, Journal of the American Chemical Society.

Nonmechanical protein can have significant mechanical stability.

Hongbin Li, Yi Cao, Yi Cao, 2006, Angewandte Chemie.

Engineering tandem modular protein based reversible hydrogels.

Hongbin Li, Yi Cao, 2008, Chemical communications.

The molecular mechanism underlying mechanical anisotropy of the protein GB1.

Guillaume Lamour, Jörg Gsponer, Peng Zheng, 2012, Biophysical journal.

Engineered bi-histidine metal chelation sites map the structure of the mechanical unfolding transition state of an elastomeric protein domain GB1.

Hongbin Li, Shulin Zhuang, Tao Shen, 2012, Biophysical journal.

Single Molecule Force Spectroscopy Studies on Metalloproteins: Opportunities and Challenges.

Hongbin Li, 2023, Langmuir : the ACS journal of surfaces and colloids.

A force-spectroscopy-based single-molecule metal-binding assay.

Hongbin Li, Yi Cao, Kai Shih Er, 2009, Chemphyschem : a European journal of chemical physics and physical chemistry.

Single Molecule Force Spectroscopy Reveals the Mechanical Design Governing the Efficient Translocation of the Bacterial Toxin Protein RTX.

Hongbin Li, Xiaoqin Gao, Han Wang, 2019, Journal of the American Chemical Society.

Reversible unfolding-refolding of rubredoxin: a single-molecule force spectroscopy study.

Hongbin Li, Yanyan Wang, Peng Zheng, 2014, Angewandte Chemie.

Stabilization provided by neighboring strands is critical for the mechanical stability of proteins.

Hui Lu, Hongbin Li, D. Sharma, 2008, Biophysical journal.

Dynamics of protein folding and cofactor binding monitored by single-molecule force spectroscopy.

Hongbin Li, Yi Cao, 2011, Biophysical journal.

The unfolding and folding dynamics of TNfnALL probed by single molecule force-ramp spectroscopy

Hongbin Li, Yi Cao, Yi Cao, 2006 .

Dynamic protein self-assembly driven by host-guest chemistry and the folding-unfolding feature of a mutually exclusive protein.

Hongbin Li, Q. Luo, C. Hou, 2017, Chemical communications.

Kinetic partitioning mechanism governs the folding of the third FnIII domain of tenascin-C: evidence at the single-molecule level.

Hongbin Li, Jie Fang, Qing Peng, 2011, Journal of molecular biology.

Direct observation of tug-of-war during the folding of a mutually exclusive protein.

Hongbin Li, Qing Peng, 2009, Journal of the American Chemical Society.

Optically controlled reversible protein hydrogels based on photoswitchable fluorescent protein Dronpa.

Linglan Fu, Hongbin Li, Junqiu Liu, 2017, Chemical communications.

Dynamic protein hydrogels with reversibly tunable stiffness regulate human lung fibroblast spreading reversibly.

Hongbin Li, G. Tanentzapf, Amanda Haage, 2019, Chemical communications.

Rationally Designed Dynamic Protein Hydrogels with Reversibly Tunable Mechanical Properties

Hongbin Li, Qing Peng, Na Kong, 2014 .

Improved single molecule force spectroscopy using micromachined cantilevers

Thomas T. Perkins, T. Perkins, Hongbin Li, 2014 .

Modulating the mechanical stability of extracellular matrix protein tenascin-C in a controlled and reversible fashion.

Hongbin Li, Shulin Zhuang, Yi Cao, 2009, Journal of molecular biology.

Modulating the Mechanical Stability of Extracellular Matrix Protein Tenascin-C in a Controlled and Reversible Fashion

Hongbin Li, Shulin Zhuang, Yi Cao, 2010 .

Atomic force microscopy reveals the mechanical design of a modular protein.

H Li, J. Clarke, A. Oberhauser, 2000, Proceedings of the National Academy of Sciences of the United States of America.

Atomic levers control pyranose ring conformations.

A. Oberhauser, J. M. Fernández, Hongbin Li, 1999, Proceedings of the National Academy of Sciences of the United States of America.

Mechanical design of proteins studied by single-molecule force spectroscopy and protein engineering.

A. Oberhauser, J. M. Fernández, Hongbin Li, 2000, Progress in biophysics and molecular biology.

Mechanical unfolding intermediates in titin modules

K. Schulten, Hui Lu, A. Oberhauser, 1999, Nature.

Single molecule force spectroscopy reveals that iron is released from the active site of rubredoxin by a stochastic mechanism.

Hongbin Li, A. Mauk, Peng Zheng, 2013, Journal of the American Chemical Society.

Atomic force microscopy reveals parallel mechanical unfolding pathways of T4 lysozyme: Evidence for a kinetic partitioning mechanism

Hongbin Li, Qing Peng, 2008, Proceedings of the National Academy of Sciences.

Decorating a Blank Slate Protein Hydrogel: A General and Robust Approach for Functionalizing Protein Hydrogels.

Hongbin Li, Xiaoye Gao, Shanshan Lyu, 2017, Biomacromolecules.

Effects of Cysteine Proteases on the Structural and Mechanical Properties of Collagen Fibers*

Hongbin Li, Xin Du, D. Brömme, 2013, The Journal of Biological Chemistry.

The adenylate cyclase toxin RTX domain follows a series templated folding mechanism with implications for toxin activity

Hongbin Li, J. Mašín, P. Šebo, 2023, The Journal of biological chemistry.

Two-Molecule Force Spectroscopy on Proteins.

Hongbin Li, Jiacheng Zuo, 2023, ACS nano.

How do chemical denaturants affect the mechanical folding and unfolding of proteins?

Hongbin Li, Yi Cao, 2008, Journal of molecular biology.

Tandem modular protein-based hydrogels constructed using a novel two-component approach.

Hongbin Li, Shanshan Lv, Yi Cao, 2012, Langmuir : the ACS journal of surfaces and colloids.

The molecular mechanism underlying mechanical anisotropy of the protein GB1.

Hongbin Li, Guillaume Lamour, Yongnan Li, 2012, Biophysical journal.

Construction and characterization of kilobasepair densely labeled peptide-DNA.

E. Bromley, P. Curmi, N. R. Forde, 2014, Biomacromolecules.

Dynamic protein hydrogels with reversibly tunable stiffness regulate human lung fibroblast spreading reversibly.

Hongbin Li, Amanda Haage, Na Kong, 2019, Chemical communications.

Twist and Shout: Single-Molecule Mechanochemistry.

Hongbin Li, G. Walker, 2017, ACS nano.

Direct observation of markovian behavior of the mechanical unfolding of individual proteins.

Hongbin Li, R. Kuske, Yi Cao, 2008, Biophysical journal.

Nanomechanical properties of tenascin-X revealed by single-molecule force spectroscopy.

Hongbin Li, A. Jollymore, Yi Cao, 2009, Journal of molecular biology.

Dynamic protein self-assembly driven by host-guest chemistry and the folding-unfolding feature of a mutually exclusive protein.

Hongbin Li, Q. Luo, C. Hou, 2017, Chemical communications.