C. Kwok

发表

In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features

Y. Zhang, Yiliang Ding, Yin Tang, 2013, Nature.

Determination of in vivo RNA structure in low-abundance transcripts

Yiliang Ding, Yin Tang, C. Kwok, 2013, Nature Communications.

The RNA structurome: transcriptome-wide structure probing with next-generation sequencing.

Yin Tang, C. Kwok, P. Bevilacqua, 2015, Trends in biochemical sciences.

Detecting RNA G-Quadruplexes (rG4s) in the Transcriptome.

S. Balasubramanian, C. Kwok, Giovanni Marsico, 2018, Cold Spring Harbor perspectives in biology.

Revealing lncRNA Structures and Interactions by Sequencing-Based Approaches.

Pui Yan Yeung, Q. Zhang, C. Kwok, 2019, TIBS -Trends in Biochemical Sciences. Regular ed.

A hybridization-based approach for quantitative and low-bias single-stranded DNA ligation.

Yiliang Ding, C. Kwok, P. Bevilacqua, 2013, Analytical biochemistry.

Genome-wide profiling of in vivo RNA structure at single-nucleotide resolution using structure-seq

Sarah M Assmann, Chun Kit Kwok, Philip C Bevilacqua, 2015, Nature Protocols.

Specific Binding of a d ‐RNA G‐Quadruplex Structure with an l ‐RNA Aptamer

C. Kwok, Chun Chan, 2020, Angewandte Chemie.

Specific Binding of a D-RNA G-Quadruplex Structure with an L-RNA Aptamer.

C. Kwok, Chun Chan, 2020, Angewandte Chemie.

RNA G-Quadruplex Structures Mediate Gene Regulation in Bacteria

X. Deng, C. Kwok, Liang Yang, 2020, mBio.

Novel L-RNA Aptamer Controls APP Gene Expression in Cells by Targeting RNA G-Quadruplex Structure.

C. Kwok, Danyang Ji, Hei Yuen Wong, 2022, ACS applied materials & interfaces.

Lockd promotes myoblast proliferation and muscle regeneration via binding with DHX36 to facilitate 5' UTR rG4 unwinding and Anp32e translation.

Y. Li, C. Kwok, Yan Liu, 2022, Cell reports.

Recent advances in RNA structurome

Q. Zhang, Yiliang Ding, C. Kwok, 2022, Science China Life Sciences.

G-quadruplex structures : from basic understanding to biological application 1 2

C. Kwok, C. J. Merrick, Catherine J. Merrick, 2017 .

Alternative splicing modulation by G-quadruplexes

E. Miska, M. Hemberg, C. Kwok, 2019, Nature Communications.

Bringing distant DNA together

C. Kwok, Haizhou Zhao, 2021, Nature Chemical Biology.

Aptamers targeting SARS-COV-2: a promising tool to fight against COVID-19

C. Kwok, M. Juhas, Yang Zhang, 2022, Trends in Biotechnology.

Rational design and development of a universal baby spinach-based sensing platform for the detection of biomolecules.

C. Kwok, Zhaohui Li, Danyang Ji, 2019, The Analyst.

Enhanced transcriptome-wide RNA G-quadruplex sequencing for low RNA input samples with rG4-seq 2.0

E. Y. Chow, Pui Yan Yeung, Q. Zhang, 2022, BMC Biology.

Spectroscopic analysis reveals the effect of hairpin loop formation on G-quadruplex structures

C. Kwok, Hengxin Feng, 2022, RSC chemical biology.

Structural analysis reveals the formation and role of RNA G-quadruplex structures in human mature microRNAs.

Aleksandr B. Sahakyan, C. Kwok, Chun Chan, 2018, Chemical communications.

G-Quadruplex-Based Fluorescent Turn-On Ligands and Aptamers: From Development to Applications

C. Kwok, Danyang Ji, Chun Chan, 2019, Molecules.

Tuning Material States and Functionalities of G-Quadruplex-Modulated RNA-Peptide Condensates.

W. Huck, H. Shum, C. Kwok, 2023, Journal of the American Chemical Society.

Identification and targeting of G-quadruplex structures in MALAT1 long non-coding RNA

C. Kwok, Xi Mou, Shi Wei. Liew, 2021, bioRxiv.

RNA G-quadruplexes (rG4s): genomics and biological functions

E. Y. Chow, C. Kwok, T. Chan, 2021, Nucleic acids research.

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome

Giovanni Marsico, Chun Kit Kwok, Shankar Balasubramanian, 2016, Nature Methods.

Circular L-RNA aptamer promotes target recognition and controls gene activity

C. Kwok, Danyang Ji, Haizhou Zhao, 2021, Nucleic acids research.

Label-free and ratiometric detection of microRNA based on target-induced catalytic hairpin assembly and two fluorescent dyes

C. Kwok, Danyang Ji, Xi Mou, 2019, Analytical Methods.

Effect of loop sequence and loop length on the intrinsic fluorescence of G-quadruplexes.

C. Kwok, P. Bevilacqua, M. Sherlock, 2013, Biochemistry.

G-Quadruplexes: Prediction, Characterization, and Biological Application.

Chun Kit Kwok, C. Kwok, Catherine J Merrick, 2017, Trends in biotechnology.

Targeted Detection of G-Quadruplexes in Cellular RNAs**

Chun Kit Kwok, Shankar Balasubramanian, S. Balasubramanian, 2015, Angewandte Chemie.

Specific suppression of D-RNA G-quadruplex–protein interaction with an L-RNA aptamer

C. Kwok, M. I. Umar, 2020, Nucleic acids research.

Spectroscopic analysis reveals the effect of a single nucleotide bulge on G-quadruplex structures.

Chun Kit Kwok, C. Kwok, Chun-Yin Chan, 2019, Chemical communications.

Steady-State and Time-Resolved Studies into the Origin of the Intrinsic Fluorescence of G-Quadruplexes.

M. Maroncelli, C. Kwok, P. Bevilacqua, 2016, The journal of physical chemistry. B.

Amyloid Precursor Protein Translation Is Regulated by a 3’UTR Guanine Quadruplex

C. Kwok, P. Bevilacqua, Brian P. Leung, 2015, PloS one.

A stable RNA G-quadruplex within the 5'-UTR of Arabidopsis thaliana ATR mRNA inhibits translation.

Yiliang Ding, C. Kwok, P. Bevilacqua, 2015, The Biochemical journal.

Decrease in RNA folding cooperativity by deliberate population of intermediates in RNA G-quadruplexes.

C. Kwok, P. Bevilacqua, M. Sherlock, 2013, Angewandte Chemie.

Discovery of G-quadruplex-forming sequences in SARS-CoV-2

Chun Kit Kwok, Mario Juhas, Yang Zhang, 2020, Briefings Bioinform..

Development of RNA G-quadruplex (rG4)-targeting l-RNA aptamers by rG4-SELEX

C. Kwok, C. Chan, M. I. Umar, 2022, Nature Protocols.

High-throughput characterization of the role of non-B DNA motifs on promoter function

Stephan J Sanders, Vikram Agarwal, M. Hemberg, 2022, Cell genomics.

An ultra low-input method for global RNA structure probing uncovers Regnase-1-mediated regulation in macrophages

Q. Zhang, C. Kwok, Lei Tang, 2021, Fundamental research.

Dawn of the in vivo RNA structurome and interactome.

Chun Kit Kwok, C. Kwok, 2016, Biochemical Society transactions.

Translational control by DHX36 binding to 5′UTR G-quadruplex is essential for muscle stem-cell regenerative functions

C. Mann, Y. Nagamine, C. Kwok, 2021, Nature Communications.

Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing

Xi Mou, Ting-Fung Chan, E. Y. Chow, 2019, Scientific Reports.

NMR proton chemical shift prediction of T·T mismatches in B-DNA duplexes.

C. Kwok, S. L. Lam, 2007, Journal of magnetic resonance.

StructureFold: genome-wide RNA secondary structure mapping and reconstruction in vivo

Anton Nekrutenko, Yin Tang, Sarah M. Assmann, 2015, Bioinform..

RNA G-quadruplex structure contributes to cold adaptation in plants

J. Zhang, Yiliang Ding, C. Kwok, 2022, bioRxiv.

COMRADES determines in vivo RNA structures and interactions

Aaron T. L. Lun, J. Marioni, I. MacRae, 2018, Nature Methods.

RNA G-quadruplex structures exist and function in vivo in plants

Yiliang Ding, C. Kwok, Yueying Zhang, 2020, Genome biology.

RNA G-quadruplex structures exist and function in vivo in plants

Yiliang Ding, C. Kwok, Yueying Zhang, 2019, Genome Biology.

Preferential base pairing modes of T·T mismatches

C. Kwok, S. L. Lam, Guoyun He, 2011, FEBS letters.

G-quadruplex RNA motifs influence gene expression in the malaria parasite Plasmodium falciparum

E. Y. Chow, C. Kwok, F. Dumetz, 2021, bioRxiv.

Capture-SELEX: Selection Strategy, Aptamer Identification, and Biosensing Application

C. Kwok, Hill Lam Lau, Sin Yu Lam, 2022, Biosensors.

Modified nucleic acid aptamers: development, characterization, and biological applications.

C. Kwok, Danyang Ji, Hengxin Feng, 2023, Trends in biotechnology.

Emergence of vascular plants

Yiliang Ding, C. Kwok, 2018, Nature Plants.

Emergence of vascular plants

Yiliang Ding, C. Kwok, 2018, Nature Plants.

Structural analysis and cellular visualization of APP RNA G-quadruplex† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc02768h

C. Kwok, Shuo-Bin Chen, Jia-Heng Tan, 2019, Chemical science.

A G-quadruplex structure in microRNA interferes with messenger RNA recognition and controls gene expression.

C. Kwok, Kaixin Lyu, 2023, Chemical communications.

Effect of RNA sequence context and stereochemistry on G-quadruplex-RHAU53 interaction.

C. Kwok, Xi Mou, 2020, Biochemical and biophysical research communications.

rG4-seq 2.0: enhanced transcriptome-wide RNA G-quadruplex structure sequencing for low RNA input samples

E. Y. Chow, Pui Yan Yeung, Q. Zhang, 2022, bioRxiv.

rG4-seeker enables high-confidence identification of novel and non-canonical rG4 motifs from rG4-seq experiments

E. Y. Chow, C. Kwok, T. Chan, 2020, bioRxiv.

Structural Analysis using SHALiPE to Reveal RNA G‐Quadruplex Formation in Human Precursor MicroRNA

Aleksandr B. Sahakyan, S. Balasubramanian, C. Kwok, 2016, Angewandte Chemie.

mRNA translation control by Dhx36 binding to 5’UTR G-quadruplex structures is essential for skeletal muscle stem cell regenerative functions

C. Mann, Y. Nagamine, C. Kwok, 2020 .

DHX36 binding induces RNA structurome remodeling and regulates RNA abundance via m6A/YTHDF1

Yiliang Ding, C. Kwok, Xiaona Chen, 2023, bioRxiv.

The in vivo RNA structurome of the malaria parasite Plasmodium falciparum, a protozoan with an A/U-rich transcriptome

Anton J. Enright, C. Kwok, F. Dumetz, 2022, bioRxiv.

COMRADES determines in vivo RNA structures and interactions

Aaron T. L. Lun, Ian Goodfellow, John C Marioni, 2018, Nature Methods.

FoldAtlas: a repository for genome-wide RNA structure probing data

Matthew Norris, Matthew Hartley, Richard J. Morris, 2016, Bioinform..

In vivo genome-wide profiling of RNA secondary structure reveals novel regulatory features

Yiliang Ding, Yin Tang, C. Kwok, 2013, Nature.

Determination of in vivo RNA structure in low-abundance transcripts

Yiliang Ding, Yin Tang, C. Kwok, 2013, Nature Communications.