M. Schlabach

发表

A Genome-wide RNAi Screen Identifies Multiple Synthetic Lethal Interactions with the Ras Oncogene

Michael J. Emanuele, S. Elledge, Kwok-Kin Wong, 2009, Cell.

Synthetic design of strong promoters

S. Elledge, M. Schlabach, Mamie Z. Li, 2010, Proceedings of the National Academy of Sciences.

A Genetic Screen for Candidate Tumor Suppressors Identifies REST

L. Chin, S. Elledge, B. Feng, 2005, Cell.

Cancer Proliferation Gene Discovery Through Functional Genomics

Ji Luo, Qikai Xu, Stephen J. Elledge, 2008, Science.

Profiling Essential Genes in Human Mammary Cells by Multiplex RNAi Screening

Stephen J. Elledge, Michael R. Schlabach, Kenneth Chang, 2008, Science.

A resource for large-scale RNA-interference-based screens in mammals

Patrick J. Paddison, Stephen J. Elledge, Kenneth Chang, 2004, Nature.

Second-generation shRNA libraries covering the mouse and human genomes

Patrick J. Paddison, R. Sachidanandam, S. Elledge, 2005, Nature Genetics.

Recurrent Hemizygous Deletions in Cancers May Optimize Proliferative Potential

M. Meyerson, S. Elledge, R. Beroukhim, 2012, Science.

CRISPR Screens Provide a Comprehensive Assessment of Cancer Vulnerabilities but Generate False-Positive Hits for Highly Amplified Genomic Regions.

Joshua M. Korn, Eric Billy, Tobias Schmelzle, 2016, Cancer discovery.

The reaction of ferric salts with transferrin.

M. Schlabach, G. Bates, 1973, The Journal of biological chemistry.

TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Cancer

Henry W. Long, W. Sellers, Myles A Brown, 2018, Cell reports.

The synergistic binding of anions and Fe3+ by transferrin. Implications for the interlocking sites hypothesis.

M. Schlabach, G. Bates, 1975, The Journal of biological chemistry.

Use of denaturing HPLC to provide efficient detection of mutations causing familial hypercholesterolemia.

A. Beaudet, D. Bercovich, C. Ballantyne, 2002, Clinical chemistry.

Correction: KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

W. Hahn, A. Redig, N. Ilić, 2017, eLife.

Project DRIVE: A Compendium of Cancer Dependencies and Synthetic Lethal Relationships Uncovered by Large-Scale, Deep RNAi Screening

Antoine de Weck, Joshua M. Korn, Eric Billy, 2017, Cell.

Abstract B21: CRISPR screens provide a comprehensive assessment of cancer vulnerabilities but generate false-positive hits for highly amplified genomic regions

F. Stegmeier, M. Schlabach, D. Muñoz, 2017 .

The Synergistic Binding of Anions and Fe 3 + by Transferrin

M. Schlabach, G. Bates, 2002 .

Studying clonal dynamics in response to cancer therapy using high-complexity barcoding

Joshua M. Korn, Franziska Michor, Derek Y. Chiang, 2015, Nature Medicine.

The nonspecific binding of Fe3+ to transferrin in the absence of synergistic anions.

M. Schlabach, G. Bates, 1975, The Journal of biological chemistry.

Does transferrin exhibit ferroxidase activity?

M. Schlabach, G. Bates, E. Workman, 1973, Biochemical and biophysical research communications.

Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to dependence on PRMT5

Konstantinos J. Mavrakis, John A. Tallarico, W. Sellers, 2016, Science.

Tumor-derived IFN triggers chronic pathway agonism and sensitivity to ADAR loss

Joshua M. Korn, J. Korn, Michael D. Jones, 2018, Nature Medicine.

KEAP1 loss modulates sensitivity to kinase targeted therapy in lung cancer

John G Doench, W. Hahn, A. Redig, 2017, eLife.

A SUMOylation-Dependent Transcriptional Subprogram Is Required for Myc-Driven Tumorigenesis

Ji Luo, Chad A Shaw, Qikai Xu, 2012, Science.

Maintenance of adenomatous polyposis coli (APC)-mutant colorectal cancer is dependent on Wnt/β-catenin signaling

William R Sellers, R. Mosher, W. Sellers, 2011, Proceedings of the National Academy of Sciences.

Design of 240,000 orthogonal 25mer DNA barcode probes

Qikai Xu, S. Elledge, G. Hannon, 2009, Proceedings of the National Academy of Sciences.

Genome-wide shRNA screen revealed integrated mitogenic signaling between dopamine receptor D2 (DRD2) and epidermal growth factor receptor (EGFR) in glioblastoma

W. Cavenee, F. Furnari, D. Kozono, 2014, Oncotarget.

A genetic screen identifies FAN1, a Fanconi anemia-associated nuclease necessary for DNA interstrand crosslink repair.

J Wade Harper, S. Elledge, T. Kunkel, 2010, Molecular cell.

A chemical genetics approach for the functional assessment of novel cancer genes.

A. Derti, D. Ruddy, F. Stegmeier, 2015, Cancer research.

A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

J Wade Harper, Steven P Gygi, Britt Adamson, 2010, Molecular cell.

Genetic interrogation of replicative senescence uncovers a dual role for USP28 in coordinating the p53 and GATA4 branches of the senescence program

S. Elledge, Qikai Xu, Ji Luo, 2017, Genes & development.

Abstract 3091: A sumoylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis

M. Rao, C. Shaw, S. Elledge, 2012 .

A study of the anion binding site of transferrin

M. Schlabach, G. Bates, 1973, FEBS letters.

Development of KSQ-4279 as a first-in-class USP1 inhibitor for the treatment of BRCA-deficient cancers

F. Stegmeier, M. Schlabach, S. Shenker, 2020 .

Abstract LB-017: Disordered methionine metabolism in MTAP/CDKN2A-deleted cancers leads to marked dependence on PRMT5

Konstantinos J. Mavrakis, Jeffrey A. Porter, W. Sellers, 2016 .

Rational design of a SOCS1-edited tumor infiltrating lymphocyte therapy for solid tumors using CRISPR/Cas9 screens

G. Kryukov, F. Stegmeier, M. Schlabach, 2023, bioRxiv.