C. Ward

发表

Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer.

F. Cappuzzo, W. Brugger, N. Triller, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

New strategies for targeting the hypoxic tumour microenvironment in breast cancer.

A. Harris, C. Supuran, C. Ward, 2013, Cancer treatment reviews.

HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer

C. Ward, A. Turnbull, S. Langdon, 2019, Breast Cancer Research.

Induction of human neutrophil apoptosis by nitric oxide donors: evidence for a caspase-dependent, cyclic-GMP-independent, mechanism.

I. Rahman, C. Haslett, C. Ward, 2000, Biochemical pharmacology.

Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

Christopher Haslett, Ian Dransfield, Elvira Crescenzi, 2006, Nature Medicine.

Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inflammation.

C. Haslett, C. Ward, A. Rossi, 2003, The Journal of endocrinology.

Targeting tumour hypoxia to prevent cancer metastasis. From biology, biosensing and technology to drug development: the METOXIA consortium

P. Lambin, L. Dubois, A. Harris, 2015, Journal of enzyme inhibition and medicinal chemistry.

Novel flavonoids as anti-cancer agents: mechanisms of action and promise for their potential application in breast cancer.

C. Ward, D. Harrison, P. Mullen, 2014, Biochemical Society transactions.

Biocompatibility of common implantable sensor materials in a tumor xenograft model

Alan F. Murray, A. Tsiamis, C. Ward, 2018, Journal of biomedical materials research. Part B, Applied biomaterials.

Pharmacological manipulation of granulocyte apoptosis: potential therapeutic targets.

C. Haslett, C. Ward, E. Chilvers, 1999, Trends in pharmacological sciences.

Interleukin‐10 inhibits lipopolysaccharide‐induced survival and extracellular signal‐regulated kinase activation in human neutrophils

C. Haslett, C. Ward, A. Rossi, 2005, European journal of immunology.

Ovine Pulmonary Adenocarcinoma: A Unique Model to Improve Lung Cancer Research.

C. Ward, D. Argyle, R. Gregson, 2019, Frontiers in oncology.

Ureido-substituted sulfamates show potent carbonic anhydrase IX inhibitory and antiproliferative activities against breast cancer cell lines.

C. Supuran, A. Scozzafava, J. Winum, 2012, Bioorganic & medicinal chemistry letters.

Fibronectin via Integrin and Decreases Attachment to In vivo Tumorigenicity Gene Expression Abolishes Ovarian Cancer

A. Paige, H. Gabra, C. Ward, 2009 .

Role of leukotrienes in the regulation of human granulocyte behaviour: dissociation between agonist‐induced activation and retardation of apoptosis

C. Haslett, C. Ward, E. Chilvers, 2003, British journal of pharmacology.

Apoptosis: future perspectives.

C. Haslett, C. Ward, I. Dransfield, 2003, Essays in biochemistry.

Oxygen levels determine the ability of glucocorticoids to influence neutrophil survival in inflammatory environments

J. Marwick, C. Haslett, C. Ward, 2013, Journal of leukocyte biology.

Eosinophil Morphology: Transcriptional regulation of eosinophil apoptosis☆

C. Haslett, C. Ward, I. Dransfield, 2000 .

Regulation of granulocyte apoptosis by hemopoietic growth factors, cytokines and drugs: potential relevance to allergic inflammation.

C. Haslett, C. Ward, I. Dransfield, 2003, Current drug targets. Inflammation and allergy.

Inhibition of nuclear factor‐κB activation un‐masks the ability of TNF‐α to induce human eosinophil apoptosis

C. Haslett, C. Ward, R. Hay, 2002 .

Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis.

C. Haslett, C. Ward, R. Hay, 2002, European journal of immunology.

Edinburgh Research Explorer HER2 regulates HIF-2 and drives an increased hypoxic response in breast cancer

C. Ward, A. Turnbull, S. Langdon, 2019 .

Corrigendum: Cyclin-dependent kinase inhibitors enhance the resolution of inflammation by promoting inflammatory cell apoptosis

E. Crescenzi, C. Haslett, C. Ward, 2006, Nature Network Boston.

Role of neutrophil apoptosis in the resolution of pulmonary inflammation.

C. Ward, E. Chilvers, J. Murray, 1999, Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace.

Regulation of neutrophil apoptosis and removal of apoptotic cells.

C. Haslett, C. Ward, S. Hart, 2005, Current drug targets. Inflammation and allergy.

Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment.

Alan F. Murray, C. Ward, D. Argyle, 2019, Current topics in microbiology and immunology.

Predictive markers of endocrine response in breast cancer

C. Ward, A. Turnbull, S. Langdon, 2018, World journal of experimental medicine.

Expression of glycolytic enzymes in ovarian cancers and evaluation of the glycolytic pathway as a strategy for ovarian cancer treatment

C. Ward, A. Turnbull, S. Langdon, 2018, BMC Cancer.

Development and characterisation of acquired radioresistant breast cancer cell lines

C. Ward, A. Turnbull, L. Pang, 2019, Radiation Oncology.

WWOX gene expression abolishes ovarian cancer tumorigenicity in vivo and decreases attachment to fibronectin via integrin alpha3.

A. Paige, H. Gabra, C. Ward, 2009, Cancer research.

Carbonic anhydrase inhibitors based on sorafenib scaffold: Design, synthesis, crystallographic investigation and effects on primary breast cancer cells.

Abdul-Malek S. Al-Tamimi, C. Supuran, M. Ferraroni, 2019, European journal of medicinal chemistry.

Technical innovation in adjuvant radiotherapy: Evolution and evaluation of new treatments for today and tomorrow.

C. Ward, I. Kunkler, S. Langdon, 2015, Breast.

Personalisation of Radiotherapy for Breast Cancer

F. Feng, L. Pierce, C. Ward, 2016 .

Exploratory analyses EGFR, kRAS mutations and other molecular markers in tumors of NSCLC patients (pts) treated with chemotherapy +/- erlotinib (TALENT)

G. Sauter, J. Moecks, U. Gatzemeier, 2005 .

Randomized phase II trial of the efficacy and safety of trastuzumab combined with docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer administered as first-line treatment: the M77001 study group.

David Grimes, Dominique Maraninchi, Ana Lluch, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

The impact of tumour pH on cancer progression: strategies for clinical intervention

Alan F. Murray, C. Ward, D. Argyle, 2020, Exploration of targeted anti-tumor therapy.

NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosis in Vitro*

C. Haslett, C. Ward, E. Chilvers, 1999, The Journal of Biological Chemistry.

HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer

C. Ward, A. Turnbull, S. Langdon, 2019, Breast Cancer Research.

Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models

C. Ward, A. Turnbull, D. Harrison, 2016, British Journal of Cancer.

Investigation of the role of ROS modulation in the antitumour effect of a novel breast cancer drug

C. Ward, D. Harrison, P. Mullen, 2014 .

Carbonic Anhydrase IX (CAIX), Cancer, and Radiation Responsiveness

C. Ward, D. Argyle, I. Kunkler, 2018, Metabolites.

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017, Oncotarget.

Oncotarget paper published

C. Supuran, C. Ward, A. Turnbull, 2017 .

Explorer Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

C. Supuran, C. Ward, A. Turnbull, 2017 .

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

P. Lambin, L. Dubois, C. Supuran, 2015, Oncotarget.

Implantable Microsystems for Personalised Anticancer Therapy

Stewart Smith, A. Tsiamis, Brian Flynn, 2018 .

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

C. Ward, A. Turnbull, S. Langdon, 2015, Oncotarget.

Prostaglandin D2 and Its Metabolites Induce Caspase-Dependent Granulocyte Apoptosis That Is Mediated Via Inhibition of IκBα Degradation Using a Peroxisome Proliferator-Activated Receptor-γ-Independent Mechanism1

C. Haslett, C. Ward, S. Farrow, 2002, The Journal of Immunology.

Proliferator-Activated Receptor-Degradation Using a Peroxisome α B κ That Is Mediated Via Inhibition of I Caspase-Dependent Granulocyte Apoptosis and Its Metabolites Induce 2 Prostaglandin

C. Haslett, C. Ward, S. Farrow, 2002 .

Implantable biosensors and their contribution to the future of precision medicine.

Alan F. Murray, M Gray, J Meehan, 2018, Veterinary journal.

HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer

C. Ward, A. Turnbull, S. Langdon, 2019, Breast Cancer Research.

Golgi fragmentation during Fas-mediated apoptosis is associated with the rapid loss of GM130.

C. Haslett, C. Ward, I. Dransfield, 2004, Biochemical and biophysical research communications.

Granulocyte Apoptosis and Macrophage Clearance of Apoptotic Cells as Targets for Pharmacological Intervention in Inflammatory Diseases

C. Haslett, C. Ward, I. Dransfield, 2006 .

Regulation of granulocyte apoptosis by NF-kappaB.

C. Haslett, C. Ward, I. Dransfield, 2004, Biochemical Society transactions.

Getting to grips with the granulocyte: manipulation of granulocyte behaviour and apoptosis by protein transduction methods.

C. Ward, I. Dransfield, A. Rossi, 2004, Biochemical Society Transactions.

Prostaglandin D2 and its metabolites induce caspase-dependent granulocyte apoptosis that is mediated via inhibition of I kappa B alpha degradation using a peroxisome proliferator-activated receptor-gamma-independent mechanism.

C. Haslett, C. Ward, S. Farrow, 2002, Journal of immunology.

A comparative analysis of inhibitors of the glycolysis pathway in breast and ovarian cancer cell line models

C. Ward, A. Turnbull, S. Langdon, 2015 .

Ovine Pulmonary Adenocarcinoma: A Unique Model to Improve Lung Cancer Research.

C. Ward, D. Argyle, R. Gregson, 2019, Frontiers in Oncology.

Oncotarget paper published

C. Supuran, C. Ward, A. Turnbull, 2017 .

MECHANISMS OF STEROID ACTION AND RESISTANCE IN INFLAMMATION Glucocorticoid-mediated regulation of granulocyte apoptosis and macrophage phagocytosis of apoptotic cells: implications for the resolution of inﬂammation

C. Haslett, C. Ward, I. Dransfield, 2003 .

Prospective molecular marker analyses of EGFR and KRAS from a randomized, placebo-controlled study of erlotinib maintenance therapy in advanced non-small-cell lung cancer.

F. Cappuzzo, W. Brugger, N. Triller, 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.