D. Korzhnev

发表

Low-populated folding intermediates of Fyn SH3 characterized by relaxation dispersion NMR

C. Dobson, L. Kay, X. Salvatella, 2004, Nature.

Propagation of dynamic changes in barnase upon binding of barstar: an NMR and computational study.

Dmitry M Korzhnev, Vladislav Yu Orekhov, Martin Billeter, 2007, Journal of molecular biology.

An NMR experiment for the accurate measurement of heteronuclear spin-lock relaxation rates.

L. Kay, D. Torchia, D. Korzhnev, 2002, Journal of the American Chemical Society.

Intrinsic dynamics of an enzyme underlies catalysis

L. Kay, D. A. Bosco, E. Eisenmesser, 2005, Nature.

Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins

C. Arrowsmith, D. Korzhnev, D. Neculai, 2016, Journal of biomolecular NMR.

Multiple-quantum relaxation dispersion NMR spectroscopy probing millisecond time-scale dynamics in proteins: theory and application.

Dmitry M Korzhnev, Karin Kloiber, L. Kay, 2004, Journal of the American Chemical Society.

Virtual Pharmacophore Screening Identifies Small‐Molecule Inhibitors of the Rev1‐CT/RIR Protein–Protein Interaction

D. Korzhnev, G. Walker, Nimrat Chatterjee, 2019, ChemMedChem.

Small molecule scaffolds that disrupt the Rev1-CT/RIR protein-protein interaction.

D. Korzhnev, S. A. Chow, M. K. Hadden, 2018, Bioorganic & medicinal chemistry.

Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process.

M. Vendruscolo, D. Korzhnev, S. Gianni, 2017, Journal of the American Chemical Society.

Cross-validation of the structure of a transiently formed and low populated FF domain folding intermediate determined by relaxation dispersion NMR and CS-Rosetta.

L. Kay, D. Korzhnev, A. Vėlyvis, 2012, The journal of physical chemistry. B.

Gated electron transfers and electron pathways in azurin: a NMR dynamic study at multiple fields and temperatures.

M. Billeter, E. Kupče, V. Orekhov, 2004, Journal of molecular biology.

Backbone dynamics of the channel‐forming antibiotic zervamicin IIB studied by 15N NMR relaxation

M. Billeter, V. Orekhov, A. Arseniev, 2001, FEBS letters.

1H-15N NMR dynamic study of an isolated α-helical peptide (1–36)- bacteriorhodopsin reveals the equilibrium helix-coil transitions

V. Orekhov, A. Arseniev, D. Korzhnev, 1999 .

Mechanism of the Unfolding of Transmembrane α-Helical Segment (1−36)-Bacteriorhodopsin Studied by Molecular Dynamics Simulations

A. V. Orekhov, A. Arseniev, D. Korzhnev, 1999 .

REV1 Inhibition Enhances Radioresistance and Autophagy

D. Korzhnev, D. Argyle, Pei Zhou, 2021, Cancers.

An analysis of the effects of 1HN-(1)HN dipolar couplings on the measurement of amide bond vector orientations in invisible protein states by relaxation dispersion NMR.

L. Kay, D. Korzhnev, H. van Ingen, 2009, The journal of physical chemistry. B.

Backbone and ILV side-chain NMR resonance assignments of the catalytic domain of human deubiquitinating enzyme USP7

D. Korzhnev, I. Bezsonova, Gabrielle J. Valles, 2022, Biomolecular NMR Assignments.

Targeting the Translesion Synthesis Pathway for the Development of Anti-Cancer Chemotherapeutics.

D. Korzhnev, M. K. Hadden, 2016, Journal of medicinal chemistry.

Probing Invisible, Low-Populated States of Protein Molecules by Relaxation Dispersion NMR Spectroscopy: An Application to Protein Folding

L. Kay, D. Korzhnev, 2008 .

The folding pathway of an FF domain: characterization of an on-pathway intermediate state under folding conditions by (15)N, (13)C(alpha) and (13)C-methyl relaxation dispersion and (1)H/(2)H-exchange NMR spectroscopy.

A. Fersht, Patrik Lundström, L. Kay, 2007, Journal of molecular biology.

Off-resonance effects in 15N T2 CPMG measurements

A. Arseniev, D. Korzhnev, Eugene V. Tischenko, 2000, Journal of biomolecular NMR.

Abp1p and Fyn SH3 domains fold through similar low-populated intermediate states.

P. Neudecker, A. Zarrine-Afsar, L. Kay, 2006, Biochemistry.

Hydration and packing along the folding pathway of SH3 domains by pressure-dependent NMR.

L. Kay, D. Korzhnev, J. Forman-Kay, 2006, Biochemistry.

Multiple-site exchange in proteins studied with a suite of six NMR relaxation dispersion experiments: an application to the folding of a Fyn SH3 domain mutant.

P. Neudecker, L. Kay, A. Mittermaier, 2005, Journal of the American Chemical Society.

Side-chain interactions in the folding pathway of a Fyn SH3 domain mutant studied by relaxation dispersion NMR spectroscopy.

L. Kay, A. Mittermaier, D. Korzhnev, 2005, Biochemistry.

Protein folding by NMR.

Dmitry M Korzhnev, D. Korzhnev, A. Zhuravleva, 2017, Progress in nuclear magnetic resonance spectroscopy.

Probing invisible, low-populated States of protein molecules by relaxation dispersion NMR spectroscopy: an application to protein folding.

Dmitry M Korzhnev, L. Kay, D. Korzhnev, 2008, Accounts of chemical research.

Probing slow dynamics in high molecular weight proteins by methyl-TROSY NMR spectroscopy: application to a 723-residue enzyme.

Dmitry M Korzhnev, Karin Kloiber, L. Kay, 2004, Journal of the American Chemical Society.

NMR studies of Brownian tumbling and internal motions in proteins

M. Billeter, V. Orekhov, A. Arseniev, 2001 .

Targeting protein–protein interactions in the DNA damage response pathways for cancer chemotherapy

D. Korzhnev, K. McPherson, K. S. McPherson, 2021, RSC chemical biology.

The Rev1-Polζ translesion synthesis mutasome: Structure, interactions and inhibition.

D. Korzhnev, A. Rizzo, 2019, The Enzymes.

From Structure and Dynamics of Protein L7/L12 to Molecular Switching in Ribosome*[boxs]

A. Arseniev, D. Korzhnev, A. Gudkov, 2004, Journal of Biological Chemistry.

Dynamics of the E. coli β-Clamp Dimer Interface and Its Influence on DNA Loading.

D. Korzhnev, G. Cisneros, P. Beuning, 2019, Biophysical journal.

Identification of small molecule translesion synthesis inhibitors that target the Rev 1-CT / RIR protein-protein interaction

D. Korzhnev, G. Walker, Nimrat Chatterjee, 2018 .

Identification of Small Molecule Translesion Synthesis Inhibitors That Target the Rev1-CT/RIR Protein-Protein Interaction.

D. Korzhnev, G. Walker, Nimrat Chatterjee, 2017, ACS chemical biology.

Structural Approach To Identify a Lead Scaffold That Targets the Translesion Synthesis Polymerase Rev1

Radha Charan Dash, Zuleyha Ozen, Alessandro A Rizzo, 2018, J. Chem. Inf. Model..

Interaction between the Rev1 C-Terminal Domain and the PolD3 Subunit of Polζ Suggests a Mechanism of Polymerase Exchange upon Rev1/Polζ-Dependent Translesion Synthesis.

G. Korza, D. Korzhnev, S. D’Souza, 2016, Biochemistry.

Rev7 dimerization is important for assembly and function of the Rev1/Polζ translesion synthesis complex

M. Hemann, D. Korzhnev, S. D’Souza, 2018, Proceedings of the National Academy of Sciences.

Interaction between the Rev 1 C-Terminal Domain and the PolD 3 Subunit of Pol Suggests a Mechanism of Polymerase Exchange upon Rev 1 / Pol-Dependent

G. Korza, D. Korzhnev, S. D’Souza, 2016 .

NMR mapping of PCNA interaction with translesion synthesis DNA polymerase Rev1 mediated by Rev1-BRCT domain.

D. Korzhnev, M. Maciejewski, Y. Pustovalova, 2013, Journal of molecular biology.

HLTF's Ancient HIRAN Domain Binds 3' DNA Ends to Drive Replication Fork Reversal.

D. Korzhnev, B. Eichman, K. Cimprich, 2015, Molecular cell.

Conformational instability of the MARK3 UBA domain compromises ubiquitin recognition and promotes interaction with the adjacent kinase domain

T. Pawson, A. Zarrine-Afsar, L. Kay, 2007, Proceedings of the National Academy of Sciences.

Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1*

C. Arrowsmith, D. Korzhnev, S. Weller, 2015, The Journal of Biological Chemistry.

Evolution of Rev7 interactions in eukaryotic TLS DNA polymerase Polζ

D. Korzhnev, G. Walker, H. Erlandsen, 2022, The Journal of biological chemistry.

NMR structure and dynamics of the C-terminal domain from human Rev1 and its complex with Rev1 interacting region of DNA polymerase η.

D. Korzhnev, S. D’Souza, G. Walker, 2012, Biochemistry.

NMR characterization of copper-binding domains 4-6 of ATP7B .

D. Korzhnev, J. Forman-Kay, A. Vėlyvis, 2010, Biochemistry.

NMR detection of multiple transitions to low‐populated states in azurin

M. Billeter, V. Orekhov, D. Korzhnev, 2003, Protein science : a publication of the Protein Society.

Dynamics-modulated Biological Activity of Transforming Growth Factor β3* 210

M. Billeter, V. Orekhov, A. Arseniev, 2002, The Journal of Biological Chemistry.

Sampling of protein dynamics in nanosecond time scale by 15N NMR relaxation and self-diffusion measurements.

V. Orekhov, A. Arseniev, D. Korzhnev, 1999, Journal of biomolecular structure & dynamics.

Model-free approach beyond the borders of its applicability.

V. Orekhov, A. Arseniev, D. Korzhnev, 1997, Journal of magnetic resonance.

Backbone dynamics of (1–71)- and (1–36)bacterioopsin studied by two-dimensional 1H-15N NMR spectroscopy

V. Orekhov, A. Arseniev, D. Korzhnev, 1995, Journal of biomolecular NMR.

Processing of heteronuclear NMR relaxation data with the new software DASHA

D. Nolde, V. Orekhov, A. Arseniev, 1995 .

Manifestation of intramolecular motions on pico- and nanosecond time scales in 1H−15N NMR relaxation: Analysis of dynamic models of one- and two-helical subunits of bacterioopsin

V. Orekhov, A. Arseniev, D. Korzhnev, 1995, Journal of biomolecular NMR.

Solution NMR structure of the HLTF HIRAN domain: a conserved module in SWI2/SNF2 DNA damage tolerance proteins

C. Arrowsmith, D. Korzhnev, D. Neculai, 2016, Journal of Biomolecular NMR.

NMR Structure Note: PHD Domain from Human SHPRH

D. Korzhnev, K. Cimprich, F. Almeida, 2014 .

PHD domain from human SHPRH

D. Korzhnev, K. Cimprich, I. Bezsonova, 2013, Journal of biomolecular NMR.

PHD domain from human SHPRH

D. Korzhnev, K. Cimprich, F. Almeida, 2013, Journal of Biomolecular NMR.

PHD domain from human SHPRH Luciana E. F. MachadoYulia PustovalovaAndrew C. Kile • Alexandra PozhidaevaKarlene A. CimprichFabio C. L. Almeida • Irina BezsonovaDmitry M. Korzhnev

D. Korzhnev, I. Bezsonova, F. Almeida, 2013 .

Measurement of signs of chemical shift differences between ground and excited protein states: a comparison between H(S/M)QC and R1ρ methods

L. Kay, R. Konrat, D. Korzhnev, 2010, Journal of biomolecular NMR.

Double- and zero-quantum NMR relaxation dispersion experiments sampling millisecond time scale dynamics in proteins.

L. Kay, V. Orekhov, D. Korzhnev, 2004, Journal of the American Chemical Society.

MUNIN: Application of three-way decomposition to the analysis of heteronuclear NMR relaxation data**

Martin Billeter, M. Billeter, V. Orekhov, 2001, Journal of biomolecular NMR.

ILV methyl NMR resonance assignments of the 81 kDa E. coli β-clamp

D. Korzhnev, P. Beuning, Socheata Lim, 2022, Biomolecular NMR Assignments.

NMR resonance assignments for the nucleotide binding domains of the E. coli clamp loader complex γ subunit

D. Korzhnev, P. Beuning, I. Bezsonova, 2021, Biomolecular NMR Assignments.

NMR resonance assignments for the N-terminal domain of the δ subunit of the E. coli γ clamp loader complex

D. Korzhnev, P. Beuning, A. Rizzo, 2017, Biomolecular NMR Assignments.

NMR resonance assignments for the N-terminal domain of the δ subunit of the E. coli γ clamp loader complex

D. Korzhnev, P. Beuning, A. Rizzo, 2017, Biomolecular NMR Assignments.

NMR structure of the human Rad18 zinc finger in complex with ubiquitin defines a class of UBZ domains in proteins linked to the DNA damage response.

D. Korzhnev, I. Bezsonova, A. Rizzo, 2014, Biochemistry.

Alternate binding modes for a ubiquitin-SH3 domain interaction studied by NMR spectroscopy.

L. Kay, D. Korzhnev, Soyoung Lee, 2009, Journal of molecular biology.

Probing the Residual Structure of the Low Populated Denatured State of ADA2h under Folding Conditions by Relaxation Dispersion Nuclear Magnetic Resonance Spectroscopy.

M. Vendruscolo, D. Korzhnev, Y. Pustovalova, 2015, Biochemistry.

Structural characterization of USP7 – ICP0 interaction

C. Arrowsmith, D. Korzhnev, S. Weller, 2015 .

1H,13C and15N resonance assignment for barnase

D. Korzhnev, M. Reibarkh, A. Schulga, 2001 .

The C‐terminal domain of human Rev1 contains independent binding sites for DNA polymerase η and Rev7 subunit of polymerase ζ

D. Korzhnev, I. Bezsonova, Y. Pustovalova, 2012, FEBS letters.

A Transient and Low-Populated Protein-Folding Intermediate at Atomic Resolution

Dmitry M Korzhnev, A. Fersht, L. Kay, 2010, Science.

L. Kay, A. Mittermaier, D. Korzhnev, 2005, Journal of biomolecular NMR.

Assessment of the Effects of Increased Relaxation Dispersion Data on the Extraction of 3-site Exchange Parameters Characterizing the Unfolding of an SH3 Domain

L. Kay, D. Korzhnev, Philipp Neudecker, 2006, Journal of biomolecular NMR.

Off-resonance R(1rho) NMR studies of exchange dynamics in proteins with low spin-lock fields: an application to a Fyn SH3 domain.

L. Kay, V. Orekhov, D. Korzhnev, 2005, Journal of the American Chemical Society.

Nonnative interactions in the FF domain folding pathway from an atomic resolution structure of a sparsely populated intermediate: an NMR relaxation dispersion study.

D. Baker, A. Fersht, L. Kay, 2011, Journal of the American Chemical Society.

Probing the transition state ensemble of a protein folding reaction by pressure-dependent NMR relaxation dispersion.

L. Kay, D. Korzhnev, Yawen Bai, 2006, Journal of the American Chemical Society.

Activation Dynamics of Ubiquitin Specific Protease 7

D. Korzhnev, N. Jaiswal, I. Bezsonova, 2023, bioRxiv.

Structure‐Based Drug Design of Phenazopyridine Derivatives as Inhibitors of Rev1 Interactions in Translesion Synthesis

D. Korzhnev, B. Hao, Yunfeng Li, 2020, ChemMedChem.

Backbone and ILV side-chain methyl NMR resonance assignments of human Rev7/Rev3-RBM1 and Rev7/Rev3-RBM2 complexes

D. Korzhnev, Dane H. Geddes-Buehre, Gianluca A Arianna, 2023, Biomolecular NMR Assignments.

Conformational exchange at a C2H2 zinc-binding site facilitates redox sensing by the PML protein.

R. Szczepaniak, D. Korzhnev, S. Weller, 2023, Structure.

Conformational Dynamics of a Cysteine-Stabilized Plant Defensin Reveals an Evolutionary Mechanism to Expose Hydrophobic Residues.

D. Korzhnev, F. Almeida, A. Valente, 2018, Biochemistry.

A simple method for measuring signs of 1HN chemical shift differences between ground and excited protein states

L. Kay, G. Bouvignies, D. Korzhnev, 2010, Journal of biomolecular NMR.

Transiently populated intermediate functions as a branching point of the FF domain folding pathway

L. Kay, D. Korzhnev, T. L. Religa, 2012, Proceedings of the National Academy of Sciences.

Off-resonance R1ρ relaxation outside of the fast exchange limit: An experimental study of a cavity mutant of T4 lysozyme

L. Kay, F. Dahlquist, V. Orekhov, 2003, Journal of biomolecular NMR.

Dramatic acceleration of protein folding by stabilization of a nonnative backbone conformation.

Dmitry M Korzhnev, Alan R Davidson, A. Zarrine-Afsar, 2004, Proceedings of the National Academy of Sciences of the United States of America.