D. Loh

发表

Differential expression of bcl-2 in intestinal epithelia. Correlation with attenuation of apoptosis in colonic crypts and the incidence of colonic neoplasia.

K. Nakayama, C. Potten, A. Merritt, 1995, Journal of cell science.

Mice Lacking p27 Kip1 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

Nobuyuki Shishido, Ikuo Horii, Tomoaki Inoue, 1996, Cell.

The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development.

H. Niida, D. Loh, T. Kohwi-Shigematsu, 2000, Genes & development.

Naive CD28-deficient T cells can initiate but not sustain an in vitro antigen-specific immune response.

D. Loh, K. Nakayama, P. Lucas, 1995, Journal of immunology.

Essential role for ZAP-70 in both positive and negative selection of thymocytes

K. Nakayama, K. Nakayama, D. Loh, 1995, Nature.

Antigen-dependent clonal expansion of a trace population of antigen-specific CD4+ T cells in vivo is dependent on CD28 costimulation and inhibited by CTLA-4.

R. Karr, J. Bluestone, D. Loh, 1995, Journal of immunology.

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo.

A. Heimberger, K. Murphy, D. Loh, 1990, Science.

T-Cell Receptor Genes

D. Loh, M. Behlke, H. S. Chou, 1988 .

Transfected Drosophila cells as a probe for defining the minimal requirements for stimulating unprimed CD8+ T cells.

M. Jackson, P. A. Peterson, J. Sprent, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Evidence for CD8-independent T cell maturation in transgenic mice.

C. Nelson, D. Loh, J. Russell, 1990, Journal of immunology.

The Syk and ZAP-70 SH2-containing tyrosine kinases are implicated in pre-T cell receptor signaling.

T. Pawson, D. Loh, A. Cheng, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Requirement for CD8 beta chain in positive selection of CD8-lineage T cells.

H. Nakauchi, D. Loh, K. Nakayama, 1994, Science.

Peripheral tolerance to allogeneic class II histocompatibility antigens expressed in transgenic mice: evidence against a clonal-deletion mechanism.

P. Allen, K. Murphy, D. Loh, 1989, Proceedings of the National Academy of Sciences of the United States of America.

Expansion of natural (NK1+) T cells that express alpha beta T cell receptors in transporters associated with antigen presentation-1 null and thymus leukemia antigen positive mice

D. Loh, L. Van Kaer, S. Joyce, 1996, The Journal of experimental medicine.

No requirement for p56lck in the antigen-stimulated clonal deletion of thymocytes.

D. Loh, K. Nakayama, 1992, Science.

CD 8 Surface Levels Alter the Fate of c ~ / 3 T Cell Receptor-expressing Thymocytes in Transgenic Mice

E. Lacy, D. Loh, N. Lee, 2003 .

Positive and negative selection of an antigen receptor on T cells in transgenic mice

David M. Kranz, Rodney D. Newberry, C. Nelson, 1988, Nature.

CD 45 RA and CD 45 RBhig h Expression Induced by Thymic Selection Events

T. Mak, W. Fung-Leung, J. Penninger, 2003 .

Mouse Heart Transplantation Model-Specific Transgenic 2 C T Cells as Tracers in a dResponse to Existing Alloantigens : Using L De Novo-Developed T Cells Have Compromised

D. Loh, A. Veillette, Hongyu Luo, 1998 .

De novo-developed T cells have compromised response to existing alloantigens: using Ld-specific transgenic 2C T cells as tracers in a mouse heart transplantation model.

D. Loh, A. Veillette, D. Xu, 1998, Journal of immunology.

Positive selection of T lymphocytes on fibroblasts

D. Loh, U. Staerz, Jill Elliott, 1993, Nature.

Distinct requirements of positive and negative selection for selecting cell type and CD8 interaction.

G. Schönrich, D. Loh, G. Hämmerling, 1993, Journal of immunology.

Transgenic Mouse Model of Lymphocyte Development

D. Loh, 1993 .

Organ injury associated with extrathymic induction of immune tolerance in doubly transgenic mice.

D. Loh, L. E. Fields, 1992, Proceedings of the National Academy of Sciences of the United States of America.

CD45RA and CD45RBhigh expression induced by thymic selection events

T. Mak, W. Fung-Leung, J. Penninger, 1992, The Journal of experimental medicine.

The level of CD8 expression can determine the outcome of thymic selection

D. Kioussis, D. Loh, F. Ramsdell, 1992, Cell.

Life and death of a T cell.

D. Loh, 1991, Advances in experimental medicine and biology.

Positive and Negative Selection of T Cells: A Transgenic Model

C. Nelson, D. Loh, D. Kranz, 1989 .

Expression of a murine polyclonal T cell receptor marker correlates with the use of specific members of the V beta 8 gene segment subfamily

L. Hood, T. Braciale, D. Loh, 1987, The Journal of experimental medicine.

Functional significance of the Fas molecule in naive lymphocytes.

D. Loh, K. Nakayama, S. Senju, 1996, International immunology.

Differences between responses of naive and activated T cells to anergy induction.

D. Loh, O. Kanagawa, F. Wang, 1998, Journal of immunology.

Role of bcl-2 in the development of lymphoid cells from the hematopoietic stem cell.

H. Nakauchi, D. Loh, K. Nakayama, 1997, Blood.

Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice.

H. Nakauchi, D. Loh, K. Nakayama, 1996, The American journal of pathology.

Expression of the p56lckY505F Mutation in CD45-Deficient Mice Rescues Thymocyte Development

J. Seavitt, R. Perlmutter, K. Murphy, 1999, Molecular and Cellular Biology.

Alternative splicing of murine T-cell receptor beta-chain transcripts.

D. Loh, M. Behlke, 1986, Nature.

Functional analysis of the murine T-cell receptor beta enhancer and characteristics of its DNA-binding proteins

C. Nelson, D. Loh, R. Sen, 1990, Molecular and cellular biology.

Targeted disruption of Bcl-2af3 in mice.: Occurrence of gray hair, polycystic kidney disease, and lymphocytopenia

K. Nakayama, D. Loh, K. Nakayama, 2022 .

Cellular and peptide requirements for in vitro clonal deletion of immature thymocytes.

K. Murphy, D. Loh, K. Nakayama, 1992, Proceedings of the National Academy of Sciences of the United States of America.

Synthetic phospholipid vesicles containing a purified viral antigen and cell membrane proteins stimulate the development of cytotoxic T lymphocytes

D. Baltimore, D. Loh, H. Eisen, 1979, The Journal of experimental medicine.

Different large deletions of t cell receptor vβ genes in natural populations of mice*

D. Loh, N. Trede, P. Cazenave, 1989, European journal of immunology.

The lack of CD8α cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes

T. Mak, W. Fung-Leung, K. Ngo, 1993 .

The lack of CD8 alpha cytoplasmic domain resulted in a dramatic decrease in efficiency in thymic maturation but only a moderate reduction in cytotoxic function of CD8+ T lymphocytes.

T. Mak, W. Fung-Leung, K. Ngo, 1993, European journal of immunology.

T-cell receptor VTβ genes in natural populations of mice

D. Loh, M. Behlke, H. S. Chou, 2004, Immunogenetics.

Identification of T-cell receptor Vβ deletion mutant mouse strain AU/ssJ (H-2q) which is resistant to collagen-induced arthritis

D. Loh, M. Behlke, H. Luthra, 1989, Immunogenetics.

Differential activation of antigen-stimulated suicide and cytokine production pathways in CD4+ T cells is regulated by the antigen-presenting cell.

K. Murphy, D. Loh, C. Weaver, 1993, Journal of immunology.

Sexual preference of apparent gene conversion events in MHC genes of mice

D. Loh, D. Baltimore, 1984, Nature.

Impaired signaling in alloantigen-specific CD8+ T cells tolerized in vivo: employing a model of Ld-specific TCR transgenic mice transplanted with allogenic hearts under the cover of a short-term rapamycin treatment.

D. Loh, A. Veillette, D. Xu, 1996, Journal of immunology.

Selective expression of an antigen receptor on CD8-bearing T lymphocytes in transgenic mice

C. Nelson, D. Loh, J. Russell, 1988, Nature.

Ly-6C is a marker of memory CD8+ T cells.

J. Bluestone, D. Loh, T. Walunas, 1995, Journal of immunology.

Activated T Cells to Anergy Induction Differences Between Responses of Naive and

D. Loh, O. Kanagawa, R. Hayashi, 1997 .

Restoration of T cell development in RAG-2-deficient mice by functional TCR transgenes.

F. Alt, E. Reinherz, K. Murphy, 1993, Science.

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo.

D. Loh, M. Jenkins, K. Pape, 1994, Immunity.

Multiple gene duplication and expression of mouse bcl-2-related genes, A1.

D. Loh, K. Nakayama, S. Hatakeyama, 1998, International immunology.

Structure and diversity of the human T-cell receptor beta-chain variable region genes.

D. Loh, M. Behlke, J. Tillinghast, 1986, Science.

Murine T-cell receptor mutants with deletions of beta-chain variable region genes.

D. Loh, M. Behlke, H. S. Chou, 1986, Proceedings of the National Academy of Sciences of the United States of America.

T-cell receptor beta-chain expression: dependence on relatively few variable region genes.

D. Hartl, D. Loh, M. Behlke, 1985, Science.

T-B cell interaction inhibits spontaneous apoptosis of mature lymphocytes in Bcl-2-deficient mice

D. Loh, K. Nakayama, L. Dustin, 1995, The Journal of experimental medicine.

T cell receptor genes in an alloreactive CTL clone: implications for rearrangement and germline diversity of variable gene segments.

D. Loh, M. Behlke, H. S. Chou, 1986, The EMBO journal.

Alternative splicing of murine T-cell receptor β-chain transcripts

D. Loh, M. Behlke, 1986, Nature.

Targeted disruption of Bcl-2 alpha beta in mice: occurrence of gray hair, polycystic kidney disease, and lymphocytopenia.

D. Loh, K. Kuida, I. Negishi, 1994, Proceedings of the National Academy of Sciences of the United States of America.

Germline organization of the murine T cell receptor beta-chain genes.

C. Nelson, D. Loh, D. Chaplin, 1987, Science.

Mutations of the chloramphenicol acetyl transferase transgene driven by the immunoglobulin promoter and intron enhancer.

D. Loh, N. Motoyama, L. E. Fields, 1993, International immunology.

CD8 surface levels alter the fate of alpha/beta T cell receptor- expressing thymocytes in transgenic mice

E. Lacy, D. Loh, N. Lee, 1992, The Journal of experimental medicine.

Permissive recognition during positive selection

D. Loh, U. Staerz, R. Berg, 1996, European journal of immunology.

Positive selection of transgenic receptor-bearing thymocytes by Kb antigen is altered by Kb mutations that involve peptide binding.

C. Nelson, J. K. Pullen, L. Pease, 1990, Proceedings of the National Academy of Sciences of the United States of America.

A conserved sequence in the T-cell receptor beta-chain promoter region.

D. Loh, H. S. Chou, S. J. Anderson, 1988, Proceedings of the National Academy of Sciences of the United States of America.

V(D)J recombination and allelic exclusion of a TCR beta-chain minilocus occurs in the absence of a functional promoter.

D. Loh, J. Alvarez, S. J. Anderson, 1995, Journal of immunology.

Receptor-stimulated death pathway is opened by antigen in mature T cells.

D. Loh, J. Russell, C. White, 1991, Proceedings of the National Academy of Sciences of the United States of America.

Transcription from a murine T-cell receptor V beta promoter depends on a conserved decamer motif similar to the cyclic AMP response element

D. Loh, S. J. Anderson, S. Miyake, 1989, Molecular and cellular biology.

Molecular basis of a mouse strain-specific anti-hapten response

D. Baltimore, T. Imanishi‐Kari, D. Loh, 1983, Cell.

Identification and characterization of new murine T cell receptor beta chain variable region (V beta) genes

C. Nelson, D. Loh, M. Louie, 1989, The Journal of experimental medicine.

Tandem linkage and unusual RNA splicing of the T-cell receptor beta-chain variable-region genes.

D. Loh, M. Behlke, H. S. Chou, 1987, Proceedings of the National Academy of Sciences of the United States of America.

Thymic selection of cytotoxic T cells independent of CD8 alpha-Lck association.

W. Fung-Leung, D. Loh, M. Louie, 1993, Science.

CD8 is needed for positive selection but differentially required for negative selection of T cells during thymic ontogeny

H. Pircher, T. Mak, W. Fung-Leung, 1993, European journal of immunology.

Antigen-driven differentiation of naive Ig-transgenic B cells in vitro.

D. Loh, T. Azuma, L. Dustin, 1995, Journal of immunology.

Positive and negative selection of T lymphocytes.

C. Nelson, D. Loh, D. Kranz, 1989, Cold Spring Harbor symposia on quantitative biology.

Identification of a T cell receptor beta chain variable region, V beta 20, that is differentially expressed in various strains of mice

D. Loh, A. Six, P. Marche, 1991, The Journal of experimental medicine.

Separation of CD4+ functional responses by peptide dose in Th1 and Th2 subsets expressing the same transgenic antigen receptor.

C. Hsieh, K. Murphy, D. Loh, 1993, Cellular Immunology.

Protein kinase C regulation of terminal deoxynucleotidyl transferase.

D. Loh, J. Russell, L. E. Fields, 1989, Journal of immunology.

Genomic organization of mouse Fc gamma receptor genes.

D. Loh, D. Chaplin, J. Thompson, 1990, Proceedings of the National Academy of Sciences of the United States of America.