Q. Kaas

发表

Accurate de novo design of hyperstable constrained peptides

David Baker, James M. Olson, Thomas Szyperski, 2016, Nature.

Prediction of disulfide dihedral angles using chemical shifts† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01423j

D. A. Armstrong, Q. Kaas, K. Rosengren, 2018, Chemical science.

IMGT-Kaleidoscope, the formal IMGT-ONTOLOGY paradigm.

Jérôme Lane, Patrice Duroux, Véronique Giudicelli, 2008, Biochimie.

A new "era" for cyclotide sequencing.

D. Craik, Q. Kaas, M. Colgrave, 2010, Biopolymers.

IG, TR and IgSF, MHC and MhcSF: what do we learn from the IMGT Colliers de Perles?

Quentin Kaas, François Ehrenmann, Marie-Paule Lefranc, 2008, Briefings in functional genomics & proteomics.

IMGT unique numbering for immunoglobulin and T cell receptor constant domains and Ig superfamily C-like domains.

Mathieu Rouard, Quentin Kaas, Gérard Lefranc, 2005, Developmental and comparative immunology.

IMGT colliers de perles: Standardized sequence-structure representations of the IgSF and MhcSF superfamily domains

Quentin Kaas, Marie-Paule Lefranc, M. Lefranc, 2007 .

Structure-function relationships of the variable domains of monoclonal antibodies approved for cancer treatment.

Quentin Kaas, Marie-Paule Lefranc, Roy Jefferis, 2007, Critical reviews in oncology/hematology.

IMGT standardization for alleles and mutations of the V-LIKE-DOMAINs and C-LIKE-DOMAINs of the immunoglobulin superfamily

V. Giudicelli, M. Lefranc, G. Lefranc, 2006 .

IMGT ® , the international ImMunoGeneTics information system ® , the reference in immunogenetics and immunoinformatics

V. Giudicelli, M. Lefranc, P. Duroux, 2008 .

Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors

David John Adams, Q. Kaas, Nargis Tabassum, 2017, ACS omega.

Role of CysI–CysIII Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors

David John Adams, Q. Kaas, Nargis Tabassum, 2017, ACS omega.

Delineation of the unbinding pathway of α-conotoxin ImI from the α7 nicotinic acetylcholine receptor.

Quentin Kaas, David J Craik, D. Craik, 2012, The journal of physical chemistry. B.

NMR of plant proteins.

D. Craik, Q. Kaas, 2013, Progress in nuclear magnetic resonance spectroscopy.

Cyclic analogues of α‐conotoxin Vc1.1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain

D. Craik, David John Adams, Q. Kaas, 2018, British journal of pharmacology.

Transcriptomic Messiness in the Venom Duct of Conus miles Contributes to Conotoxin Diversity*

Q. Kaas, R. Lewis, P. Alewood, 2013, Molecular & Cellular Proteomics.

Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

J. Mattick, Q. Kaas, Shaodong Guo, 2020, Proceedings of the National Academy of Sciences.

Structural venomics: evolution of a complex chemical arsenal by massive duplication and neofunctionalization of a single ancestral fold

J. Mattick, Q. Kaas, G. King, 2018, bioRxiv.

Distinct but overlapping binding sites of agonist and antagonist at the relaxin family peptide 3 (RXFP3) receptor

Q. Kaas, K. Rosengren, R. Bathgate, 2018, The Journal of Biological Chemistry.

Development of efficient docking strategies and structure-activity relationship study of the c-Met type II inhibitors.

Q. Kaas, Ri-lei Yu, Tao Jiang, 2017, Journal of molecular graphics & modelling.

Conotoxins and Other Conopeptides

D. Craik, Q. Kaas, 2014 .

Conopeptide characterization and classifications: an analysis using ConoServer.

D. Craik, Q. Kaas, Jan-Christoph Westermann, 2010, Toxicon : official journal of the International Society on Toxinology.

ArachnoServer: a database of protein toxins from spiders

Q. Kaas, G. King, P. Escoubas, 2009, BMC Genomics.

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

Hormone-like conopeptides - new tools for pharmaceutical design.

D. Craik, Q. Kaas, Ashlin Turner, 2020, RSC medicinal chemistry.

A novel (cid:1) 4/7-conotoxin LvIA from Conus lividus that selectively blocks (cid:1) 3 (cid:2) 2 vs . (cid:1) 6/ (cid:1) 3 (cid:2) 2 (cid:2) 3 nicotinic acetylcholine receptors

D. Craik, Q. Kaas, C. Schroeder, 2014 .

Deep Venomics Reveals the Mechanism for Expanded Peptide Diversity in Cone Snail Venom*

Q. Kaas, R. Lewis, Alun Jones, 2012, Molecular & Cellular Proteomics.

Insecticidal spider toxins are high affinity positive allosteric modulators of the nicotinic acetylcholine receptor

D. Craik, Davide Sabbadin, Q. Kaas, 2019, FEBS letters.

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae.

D. Craik, Q. Kaas, S. Henriques, 2015, ACS chemical biology.

Molecular dynamics simulations of dihydro‐β‐erythroidine bound to the human α4β2 nicotinic acetylcholine receptor

D. Craik, David John Adams, Q. Kaas, 2019, British journal of pharmacology.

Design of substrate-based BCR-ABL kinase inhibitors using the cyclotide scaffold

D. Craik, Q. Kaas, Yen‐Hua Huang, 2015, Scientific Reports.

Late-Stage Functionalization with Cysteine Staples Generates Potent and Selective Melanocortin Receptor-1 Agonists.

Andrew M. White, A. Plowright, D. Craik, 2022, Journal of medicinal chemistry.

IMGT, the international ImMunoGeneTics information system®

V. Giudicelli, M. Lefranc, G. Lefranc, 2004, Nucleic acids research.

IMGT, the international ImMunoGeneTics information system (cid:1)

V. Giudicelli, M. Lefranc, G. Lefranc, 2004 .

The Cold Awakening of Doritaenopsis ‘Tinny Tender’ Orchid Flowers: The Role of Leaves in Cold-induced Bud Dormancy Release

Q. Kaas, Mingbing Zhou, Q. Qin, 2012, Journal of Plant Growth Regulation.

Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2021, Journal of medicinal chemistry.

Bioinformatics-Aided Venomics

David J. Craik, Quentin Kaas, D. Craik, 2015, Toxins.

Exploring the Sequence Diversity of Cyclotides from Vietnamese Viola Species.

D. Craik, Q. Kaas, Yen‐Hua Huang, 2020, Journal of natural products.

Discovery, synthesis, and structure-activity relationships of conotoxins.

D. Craik, Q. Kaas, R. Lewis, 2014, Chemical reviews.

Conformational Flexibility Is a Determinant of Permeability for Cyclosporin.

D. Craik, P. Harvey, Q. Kaas, 2018, The journal of physical chemistry. B.

Bioactive Compounds Isolated from Neglected Predatory Marine Gastropods

D. Craik, Q. Kaas, C. Schroeder, 2018, Marine drugs.

Conotoxins: Chemistry and Biology.

D. Craik, Q. Kaas, R. Lewis, 2019, Chemical reviews.

IMGT®, the international ImMunoGeneTics information system®

Jérôme Lane, Patrice Duroux, Marie-Paule Lefranc, 2004, Nucleic Acids Res..

Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.

D. Craik, Q. Kaas, J. McIntosh, 2021, Journal of medicinal chemistry.

CyBase: a database of cyclic protein sequences and structures, with applications in protein discovery and engineering

Conan K. L. Wang, David J. Craik, Quentin Kaas, 2007, Nucleic Acids Res..

Molecular basis for the resistance of an insect chymotrypsin to a potato type II proteinase inhibitor

D. Craik, M. Anderson, Q. Kaas, 2010, Proceedings of the National Academy of Sciences.

IMGT/3Dstructure-DB and IMGT/DomainGapAlign: a database and a tool for immunoglobulins or antibodies, T cell receptors, MHC, IgSF and MhcSF

Marie-Paule Lefranc, Quentin Kaas, François Ehrenmann, 2009, Nucleic Acids Res..

ConoServer: updated content, knowledge, and discovery tools in the conopeptide database

David J. Craik, Quentin Kaas, Rilei Yu, 2011, Nucleic Acids Res..

In Silico Design of MDM2‐Targeting Peptides from a Naturally Occurring Constrained Peptide

D. Craik, P. Harvey, Q. Kaas, 2019, ChemMedChem.

IMGT-Choreography for immunogenetics and immunoinformatics

Marie-Paule Lefranc, Véronique Giudicelli, Denys Chaume, 2004, Silico Biol..

Peptide-based LDH5 inhibitors enter cancer cells and impair proliferation

D. Craik, Q. Kaas, S. Henriques, 2022, Cellular and Molecular Life Sciences.

ArachnoServer 3.0: an online resource for automated discovery, analysis and annotation of spider toxins

Pierre-Alain Chaumeil, Michael Nuhn, Quentin Kaas, 2018, Bioinform..

ArachnoServer 2.0, an updated online resource for spider toxin sequences and structures

Greta J. Binford, Pierre-Alain Chaumeil, Quentin Kaas, 2010, Nucleic Acids Res..

Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR

D. Craik, Q. Kaas, A. Nicke, 2019, Front. Pharmacol..

Key Residues in the Nicotinic Acetylcholine Receptor β2 Subunit Contribute to α-Conotoxin LvIA Binding*

D. Craik, Q. Kaas, J. McIntosh, 2015, The Journal of Biological Chemistry.

A novel α4/7‐conotoxin LvIA from Conus lividus that selectively blocks α3β2 vs. α6/α3β2β3 nicotinic acetylcholine receptors

D. Craik, Q. Kaas, C. Schroeder, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The evolution of Momordica cyclic peptides.

D. Craik, Q. Kaas, H. Schaefer, 2015, Molecular biology and evolution.

The KNOTTIN website and database: a new information system dedicated to the knottin scaffold

Jean-Christophe Gelly, Jérôme Gracy, Dung Le-Nguyen, 2004, Nucleic Acids Res..

Cloning, synthesis, and characterization of αO-conotoxin GeXIVA, a potent α9α10 nicotinic acetylcholine receptor antagonist

D. Craik, P. Harvey, Q. Kaas, 2015, Proceedings of the National Academy of Sciences.

Development of Novel Melanocortin Receptor Agonists Based on the Cyclic Peptide Framework of Sunflower Trypsin Inhibitor-1.

Philipp M. Cromm, A. Plowright, D. Craik, 2018, Journal of medicinal chemistry.

A Practical Guide to Structural Aspects of Macrocycles (NMR, X‐Ray, and Modeling)

David J. Craik, Quentin Kaas, Conan K. Wang, 2017 .

Identification of candidates for cyclotide biosynthesis and cyclisation by expressed sequence tag analysis of Oldenlandia affinis

D. Craik, Q. Kaas, J. Suda, 2010, BMC Genomics.

Efficient enzymatic cyclization of an inhibitory cystine knot‐containing peptide

D. Craik, O. Cheneval, Q. Kaas, 2016, Biotechnology and bioengineering.

Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1

D. Craik, David John Adams, Q. Kaas, 2015, Scientific Reports.

Neuropeptide signalling systems -an underexplored target for venom drug discovery.

Q. Kaas, Markus Muttenthaler, Helen C. Mendel, 2020, Biochemical pharmacology.

αO-Conotoxin GeXIVA disulfide bond isomers exhibit differential sensitivity for various nicotinic acetylcholine receptors but retain potency and selectivity for the human α9α10 subtype

D. Craik, Q. Kaas, J. McIntosh, 2017, Neuropharmacology.

Determination of the α-conotoxin Vc1.1 binding site on the α9α10 nicotinic acetylcholine receptor.

D. Craik, David John Adams, Q. Kaas, 2013, Journal of medicinal chemistry.

Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer

D. Craik, David John Adams, P. Harvey, 2017, The Journal of Biological Chemistry.

Precursor De13.1 from Conus delessertii defines the novel G gene superfamily

Q. Kaas, L. Possani, M. Aguilar, 2013, Peptides.

Analysis and classification of circular proteins in CyBase.

D. Craik, Q. Kaas, 2010, Biopolymers.

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

D. Craik, Thomas M A Shafee, Q. Kaas, 2018, Nature Communications.

Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2023, Journal of medicinal chemistry.

IMGT-ONTOLOGY for immunogenetics and immunoinformatics

Marie-Paule Lefranc, Véronique Giudicelli, Denys Chaume, 2003, Silico Biol..

IMGT/3Dstructure-DB and IMGT/StructuralQuery, a database and a tool for immunoglobulin, T cell receptor and MHC structural data

Marie-Paule Lefranc, Manuel Ruiz, Quentin Kaas, 2004, Nucleic Acids Res..

Single Amino Acid Substitution in α-Conotoxin TxID Reveals a Specific α3β4 Nicotinic Acetylcholine Receptor Antagonist.

D. Craik, P. Harvey, Q. Kaas, 2018, Journal of medicinal chemistry.

α-Conotoxin [S9A]TxID Potently Discriminates between α3β4 and α6/α3β4 Nicotinic Acetylcholine Receptors.

D. Craik, P. Harvey, Q. Kaas, 2017, Journal of medicinal chemistry.

IMGT Standardization for Molecular Characterization of the T-cell Receptor/Peptide/MHC Complexes

Quentin Kaas, Elodie Duprat, Marie-Paule Lefranc, 2008 .

T Cell Receptor/Peptide/MHC Molecular Characterization and Standardized pMHC Contact Sites in IMGT/3Dstructure-DB

Marie-Paule Lefranc, Quentin Kaas, M. Lefranc, 2005, Silico Biol..

Interactions of Globular and Ribbon [γ4E]GID with α4β2 Neuronal Nicotinic Acetylcholine Receptor

D. Craik, Q. Kaas, Xiaosa Wu, 2021, Marine drugs.

Efficient backbone cyclization of linear peptides by a recombinant asparaginyl endopeptidase

D. Craik, Q. Kaas, T. Durek, 2015, Nature Communications.

The acyclotide ribe 31 from Rinorea bengalensis has selective cytotoxicity and potent insecticidal properties in Drosophila

Adam Claridge‐Chang, D. Craik, P. Harvey, 2022, The Journal of biological chemistry.

Structure and Activity Studies of Disulfide-Deficient Analogues of αO-Conotoxin GeXIVA.

D. Craik, P. Harvey, Q. Kaas, 2020, Journal of medicinal chemistry.

Bibliometric Review of the Literature on Cone Snail Peptide Toxins from 2000 to 2022

D. Craik, Q. Kaas, Linh T T Nguyen, 2023, Marine drugs.

Characterisation of the subunit genes of pyrophosphate-dependent phosphofructokinase from loquat (Eriobotrya japonica Lindl.)

Q. Kaas, Zhujun Zhu, Q. Qin, 2014, Tree Genetics & Genomes.

Isolation and Characterization of A Cytosolic Pyruvate Kinase cDNA From Loquat (Eriobotrya japonica Lindl.)

Q. Kaas, Q. Qin, Wei-wei Zheng, 2013, Plant Molecular Biology Reporter.

Modelling the interactions between animal venom peptides and membrane proteins

Q. Kaas, C. Schroeder, S. Kuyucak, 2017, Neuropharmacology.

Computational Studies of Snake Venom Toxins

Julio Caballero, Quentin Kaas, David Ramírez, 2017, Toxins.

High-affinity Cyclic Peptide Matriptase Inhibitors*

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013, The Journal of Biological Chemistry.

Development of cyclic peptide matriptase inhibitors

D. Craik, Q. Kaas, Yen‐Hua Huang, 2013 .

A systematic approach to document cyclotide distribution in plant species from genomic, transcriptomic, and peptidomic analysis.

D. Craik, Q. Kaas, D. Mondal, 2013, Biopolymers.

Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3

Quentin Kaas, Paul R. Gooley, Ross A. D. Bathgate, 2013, Front. Endocrin..

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

D. Craik, Q. Kaas, T. Durek, 2019, Scientific Reports.

Discovery and mechanistic studies of cytotoxic cyclotides from the medicinal herb Hybanthus enneaspermus

D. Craik, Q. Kaas, Yen‐Hua Huang, 2020, The Journal of Biological Chemistry.

Engineering of conotoxins for the treatment of pain.

D. Craik, P. Harvey, Q. Kaas, 2011, Current pharmaceutical design.

Blockade of Neuronal α7-nAChR by α-Conotoxin ImI Explained by Computational Scanning and Energy Calculations

David J. Craik, Quentin Kaas, Rilei Yu, 2011, PLoS Comput. Biol..

Cyclisation of Disulfide-Rich Conotoxins in Drug Design Applications

D. Craik, Q. Kaas, Yen‐Hua Huang, 2016 .

IMGT unique numbering for MHC groove G-DOMAIN and MHC superfamily (MhcSF) G-LIKE-DOMAIN.

Quentin Kaas, Gérard Lefranc, Elodie Duprat, 2005, Developmental and comparative immunology.

SCORE: predicting the core of protein models

Charlotte M. Deane, Tom L. Blundell, Quentin Kaas, 2001, Bioinform..

Development of novel frog‐skin peptide scaffolds with selectivity towards melanocortin receptor subtypes

D. Craik, V. Hruby, Q. Kaas, 2020 .

Melanocortin 1 Receptor Agonists Based on a Bivalent, Bicyclic Peptide Framework.

Andrew M. White, A. Plowright, D. Craik, 2021, Journal of medicinal chemistry.

KNOTTIN: the knottin or inhibitor cystine knot scaffold in 2007

Jean-Christophe Gelly, Jérôme Gracy, Dung Le-Nguyen, 2007, Nucleic Acids Res..

Mutagenesis of bracelet cyclotide hyen D reveals functionally and structurally critical residues for membrane binding and cytotoxicity

D. Craik, Q. Kaas, Yen‐Hua Huang, 2022, The Journal of biological chemistry.

Early development of Monoplex pilearis and Monoplex parthenopeus (Gastropoda: Cymatiidae): biology and morphology

D. Craik, Q. Kaas, C. Schroeder, 2020, Organisms Diversity & Evolution.

Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic alpha-Conotoxin Vc1.1

David J. Craik, Quentin Kaas, Xinying Jia, 2016 .

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

D. Craik, Q. Kaas, T. Durek, 2020, Nature Communications.

A suite of kinetically superior AEP ligases can cyclise an intrinsically disordered protein

D. Craik, Q. Kaas, T. Durek, 2019, Scientific Reports.

Molecular basis for the production of cyclic peptides by plant asparaginyl endopeptidases

D. Craik, M. Anderson, Thomas M A Shafee, 2018, Nature Communications.

A bifunctional asparaginyl endopeptidase efficiently catalyzes both cleavage and cyclization of cyclic trypsin inhibitors

D. Craik, Q. Kaas, T. Durek, 2020, Nature Communications.

Stoichiometry dependent inhibition of rat &agr;3&bgr;4 nicotinic acetylcholine receptor by the ribbon isomer of &agr;‐conotoxin AuIB

D. Craik, David John Adams, Q. Kaas, 2018, Biochemical pharmacology.

Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB

D. Craik, David John Adams, Q. Kaas, 2018 .

Enhanced Activity against Multi-drug Resistant Bacteria through Coapplication of an Analogue of Tachyplesin I and an Inhibitor of the QseC/B Signaling Pathway.

D. Craik, P. Harvey, Q. Kaas, 2020, Journal of medicinal chemistry.

Mapping the Molecular Surface of the Analgesic NaV1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions.

I. Vetter, Q. Kaas, C. Schroeder, 2020, ACS pharmacology & translational science.

ConoServer, a database for conopeptide sequences and structures

Conan K. L. Wang, David J. Craik, Quentin Kaas, 2008, Bioinform..

Creating a specialist protein resource network: a meeting report for the protein bioinformatics and community resources retreat

Neil D. Rawlings, Robert D. Finn, Alex Bateman, 2015, Database J. Biol. Databases Curation.

Creating a specialist protein resource network

Neil D. Rawlings, Alex Bateman, Bernard Henrissat, 2015 .

Prediction and characterization of cyclic proteins from sequences in three domains of life.

Lukasz Kurgan, Marcin J Mizianty, Quentin Kaas, 2014, Biochimica et biophysica acta.

Structure-Activity Relationships of Alanine Scan Mutants αO-Conotoxins GeXIVA[1,2] and GeXIVA[1,4].

D. Craik, P. Harvey, Q. Kaas, 2023, Journal of medicinal chemistry.

marine drugs

D. Craik, Q. Kaas, Linh T. T. Nguyen, 2022 .

Despite a conserved cystine knot motif, different cyclotides have different membrane binding modes.

D. Craik, Q. Kaas, Conan K. Wang, 2009, Biophysical journal.

IMGT, the international ImMunoGeneTics information system®

Marie-Paule Lefranc, Véronique Giudicelli, Denys Chaume, 2004, Nucleic Acids Res..

Cyclization of conotoxins to improve their biopharmaceutical properties.

D. Craik, Q. Kaas, N. Daly, 2012, Toxicon : official journal of the International Society on Toxinology.

NMR of plant proteins.

D. Craik, Q. Kaas, 2013, Progress in nuclear magnetic resonance spectroscopy.

Scanning mutagenesis identifies residues that improve the long-term stability and insecticidal activity of cyclotide kalata B1

D. Craik, Q. Kaas, Conan K. Wang, 2024, The Journal of biological chemistry.