Per Greisen

发表

Accurate de novo design of hyperstable constrained peptides

David Baker, James M. Olson, Thomas Szyperski, 2016, Nature.

Simultaneous Optimization of Biomolecular Energy Functions on Features from Small Molecules and Macromolecules.

David E. Kim, P. Bradley, D. Baker, 2016, Journal of chemical theory and computation.

Linear rate-equilibrium relations arising from ion channel-bilayer energetic coupling

Per Greisen, J. A. Lundbæk, O. Andersen, 2011, Proceedings of the National Academy of Sciences.

Overcoming an optimization plateau in the directed evolution of highly efficient nerve agent bioscavengers

Dan S. Tawfik, D. Baker, Y. Ashani, 2017, Protein engineering, design & selection : PEDS.

Phosphorus binding sites in proteins: structural preorganization and coordination.

Mathias F. Gruber, C. Hélix-Nielsen, Per Greisen, 2014, The journal of physical chemistry. B.

A factor VIIIa–mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

K. Lamberth, G. Røder, Per Greisen, 2021, Blood.

A structural and data-driven approach to engineering a plant cytochrome P450 enzyme

S. Ovchinnikov, Per Greisen, Sanwen Huang, 2019, Science China Life Sciences.

A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa

O. Olsen, M. Overgaard, Per Greisen, 2022, Scientific Reports.

Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites

Brian D. Weitzner, Timothy W. Craven, Stephen A. Rettie, 2021, Nature Communications.

Catalytic efficiencies of directly evolved phosphotriesterase variants with structurally different organophosphorus compounds in vitro

Dan S. Tawfik, D. Baker, Y. Ashani, 2016, Archives of Toxicology.

Engineering V-type nerve agents detoxifying enzymes using computationally focused libraries.

Dan S. Tawfik, D. Baker, Y. Ashani, 2013, ACS chemical biology.

Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis.

Ryo Takeuchi, David Baker, Joel L Sussman, 2012, Nature chemical biology.

Improvement of a synthetic live bacterial therapeutic for phenylketonuria with biosensor-enabled enzyme engineering

Jay H. Konieczka, Per Greisen, J. Konieczka, 2021, Nature Communications.

Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold.

David Baker, Lindsey Doyle, Nephi Stella, 2018, Protein engineering, design & selection : PEDS.

Computational design of environmental sensors for the potent opioid fentanyl

David Baker, Matthew J Bick, Kai Johnsson, 2017, eLife.

Removal of lycopene substrate inhibition enables high carotenoid productivity in Yarrowia lipolytica

G. Stephanopoulos, Per Greisen, Sanwen Huang, 2022, Nature Communications.

New insights into substrate folding preference of plant OSCs

S. Ovchinnikov, Per Greisen, Sanwen Huang, 2016 .

Enhanced chemoselectivity of a plant cytochrome P450 through protein engineering of surface and catalytic residues

Per Greisen, Sanwen Huang, Y. Shang, 2021, aBIOTECH.

Computational design of N‐linked glycans for high throughput epitope profiling

E. Johansson, Per Greisen, Haisun Zhu, 2023, bioRxiv.

Optimizing selectivity of anion hydrophobic multimodal chromatography for purification of a single‐chain variable fragment

Per Greisen, L. Bülow, M. B. Vester-Christensen, 2019, Engineering in life sciences.

Interaction between sodium dodecyl sulfate and membrane reconstituted aquaporins: a comparative study of spinach SoPIP2;1 and E. coli AqpZ.

C. Hélix-Nielsen, J. Torres, Per Greisen, 2011, Biochimica et biophysica acta.

Metallothionein Zn2+- and Cu2+-clusters from first-principles calculations.

Per Greisen, K. P. Kepp, J. Jespersen, 2012, Dalton transactions.

for the potent

Mauricio S. Antunes, M. J. Bick, L. Reymond, 2017 .

Designed Endocytosis-Triggering Proteins mediate Targeted Degradation

Craig L. Dobbins, Jamie B. Spangler, Kole T. Roybal, 2023, bioRxiv.

A structural and data-driven approach to engineering a plant cytochrome P450 enzyme

S. Ovchinnikov, Per Greisen, Sanwen Huang, 2019, Science China Life Sciences.

Improving the Developability of an Antigen Binding Fragment by Aspartate Substitutions.

Per Greisen, L. Bülow, Nikolai Lorenzen, 2019, Biochemistry.

Probabilistic thermal stability prediction through sparsity promoting transformer representation

J. Ferkinghoff-Borg, Per Greisen, Nikolai Lorenzen, 2022, ArXiv.

A factor VIIIa – mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice

K. Lamberth, Per Greisen, B. G. Hansen, 2021 .