B. Ryu

发表

Daedalus: a robust, turnkey platform for rapid production of decigram quantities of active recombinant proteins in human cell lines using novel lentiviral vectors

R. Strong, C. Correnti, A. Bandaranayake, 2011, Nucleic acids research.

diminish the risk for proto-oncogene activation An experimental system for the evaluation of retroviral vector design to

A. Nienhuis, B. Ryu, J. Gray, 2009 .

The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing

B. Ryu, J. Riberdy, R. Throm, 2020, Molecular therapy. Methods & clinical development.

Sustained fetal hemoglobin induction in vivo is achieved by BCL11A interference and coexpressed truncated erythropoietin receptor

B. Ryu, J. Tisdale, R. Donahue, 2021, Science Translational Medicine.

Developmentally regulated expression of MEF2C limits the response to BCR engagement in transitional B cells

B. Ryu, D. Rawlings, Sarah F. Andrews, 2012, European journal of immunology.

Real-time in vivo bioluminescence imaging of lentiviral vector-mediated gene transfer in mouse testis.

B. Ryu, H. S. Choi, S. Her, 2010, Theriogenology.

Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy

B. Ryu, D. Rawlings, Yoon-Sang Kim, 2020, Gene Therapy.

The Engraftment of Lentiviral Vector-Transduced Human CD34+ Cells into Humanized Mice.

B. Ryu, Yoon-Sang Kim, M. Wielgosz, 2019, Methods in molecular biology.

Lentiviral Gene Therapy Combined with Low‐Dose Busulfan in Infants with SCID‐X1

J. Puck, J. Church, B. Ryu, 2019, The New England journal of medicine.

A chromatin insulator blocks interactions between globin regulatory elements and cellular promoters in erythroid cells.

A. Nienhuis, B. Ryu, J. Gray, 2007, Blood cells, molecules & diseases.

Genome editing of HBG1 and HBG2 to induce fetal hemoglobin.

Shondra M. Pruett-Miller, S. Tsai, S. Wolfe, 2019, Blood advances.

Ubiquitous high-level gene expression in hematopoietic lineages provides effective lentiviral gene therapy of murine Wiskott-Aldrich syndrome.

H. Ochs, B. Ryu, D. Rawlings, 2012, Blood.

Coupling endonucleases with DNA end–processing enzymes to drive gene disruption

Sarah K. Baxter, Michael T. Certo, A. Lambert, 2012, Nature Methods.

Effective, safe, and sustained correction of murine XLA using a UCOE-BTK promoter-based lentiviral vector

B. Ryu, D. Rawlings, Joseph Pangallo, 2021, Molecular therapy. Methods & clinical development.

Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease

C. von Kalle, G. Veres, B. Ryu, 2014, Current gene therapy.

Novel reporter systems for facile evaluation of I-SceI-mediated genome editing

Nina M. Muñoz, A. Scharenberg, B. Ryu, 2011, Nucleic acids research.

functional recovery in a murine model of X-linked agammaglobulinemia specific lentiviral gene therapy leads to sustained B-cell - B cell

B. Ryu, D. Rawlings, S. Humblet-Baron, 2012 .

B cell-specific lentiviral gene therapy leads to sustained B-cell functional recovery in a murine model of X-linked agammaglobulinemia.

D. Liggitt, B. Ryu, D. Rawlings, 2010, Blood.

An experimental system for the evaluation of retroviral vector design to diminish the risk for proto-oncogene activation.

A. Nienhuis, B. Ryu, J. Gray, 2008, Blood.

Optimizing lentiviral vector transduction of hematopoietic stem cells for gene therapy

B. Ryu, D. Rawlings, Yoon-Sang Kim, 2020, Gene Therapy.

Robust erythroid differentiation system for rhesus hematopoietic progenitor cells allowing preclinical screening of genetic treatment strategies for the hemoglobinopathies.

G. Blobel, B. Ryu, J. Tisdale, 2018, Cytotherapy.

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free Media

B. Ryu, R. Throm, F. Ferrara, 2019, Molecular therapy. Methods & clinical development.

Resveratrol trimer enhances gene delivery to hematopoietic stem cells by reducing antiviral restriction at endosomes.

D. Boger, B. Torbett, B. Ryu, 2019, Blood.

Tracking genome engineering outcome at individual DNA breakpoints

David J. Rawlings, Michael T. Certo, A. Scharenberg, 2011, Nature Methods.

Targeted Entry via Somatostatin Receptors Using a Novel Modified Retrovirus Glycoprotein That Delivers Genes at Levels Comparable to Those of Wild-Type Viral Glycoproteins

B. Ryu, L. Albritton, S. Heldt, 2011, Journal of Virology.

The block to membrane fusion differs with the site of ligand insertion in modified retroviral envelope proteins.

B. Ryu, L. Albritton, T. Zavorotinskaya, 2008, The Journal of general virology.

Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.

B. Ryu, D. Rawlings, S. Humblet-Baron, 2011, Molecular therapy : the journal of the American Society of Gene Therapy.

Forced enhancer-promoter rewiring to alter gene expression in animal models

G. Blobel, B. Ryu, M. Weiss, 2023, Molecular therapy. Nucleic acids.

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque.

C. von Kalle, S. Pittaluga, W. Young, 2006, Blood.

Preclinical proof of concept for VivoVec, a lentiviral-based platform for in vivo CAR T-cell engineering

Alessandra M. Sullivan, A. Scharenberg, B. Ryu, 2023, Journal for ImmunoTherapy of Cancer.

Successful Targeting and Disruption of an Integrated Reporter Lentivirus Using the Engineered Homing Endonuclease Y2 I-AniI

A. Scharenberg, B. Ryu, D. Rawlings, 2011, PloS one.

hematopoietic progenitor cells in a rhesus macaque Acute myeloid leukemia is associated with retroviral gene transfer to

Young, S. Pittaluga, B. Ryu, 2014 .

A Novel and Highly Potent CAR T Cell Drug Product for Treatment of BCMA-Expressing Hematological Malignances

R. Morgan, B. Ryu, John W. Evans, 2015 .

Acute myeloid leukemia is associated with retroviral gene transfer to hematopoietic progenitor cells in a rhesus macaque.

C. von Kalle, S. Pittaluga, A. Nienhuis, 2006, Blood.