B. Weisblum

发表

Design of non-cysteine-containing antimicrobial beta-hairpins: structure-activity relationship studies with linear protegrin-1 analogues.

S. Gellman, J. Lai, B. Huck, 2002, Biochemistry.

Surface Plasmon Resonance Imaging of Transcription Factor Proteins: Interactions of Bacterial Response Regulators with DNA Arrays on Gold Films†

Emily A. Smith, R. Corn, B. Weisblum, 2003 .

Structure-activity studies of 14-helical antimicrobial beta-peptides: probing the relationship between conformational stability and antimicrobial potency.

S. Gellman, B. Weisblum, T. L. Raguse, 2002, Journal of the American Chemical Society.

Mimicry of Host-Defense Peptides by Unnatural Oligomers: Antimicrobial β-Peptides

S. Gellman, B. Weisblum, E. Porter, 2002 .

Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.

S. Gellman, K. Satyshur, B. Weisblum, 2015, Journal of the American Chemical Society.

Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid

T. Tanaka, B. Weisblum, T. Tanaka, 1975, Journal of bacteriology.

Altered methylation of ribosomal RNA in an erythromycin-resistant strain of Staphylococcus aureus.

B. Weisblum, C. Lai, 1971, Proceedings of the National Academy of Sciences of the United States of America.

Control of Gene Expression and Replication in Plasmids pE194 and pC194

S. Horinouchi, B. Weisblum, 1982 .

Nylon-3 polymers active against drug-resistant Candida albicans biofilms.

S. Falk, S. Gellman, B. Weisblum, 2015, Journal of the American Chemical Society.

Nylon-3 polymers with selective antifungal activity.

S. Falk, S. Gellman, B. Weisblum, 2013, Journal of the American Chemical Society.

Effects of Cyclic vs. Acyclic Hydrophobic Subunits on the Chemical Structure and Biological Properties of Nylon-3 Co-Polymers.

S. Gellman, B. Weisblum, Runhui Liu, 2013, ACS macro letters.

Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides.

S. Gellman, B. Weisblum, S. Stahl, 2009, Journal of the American Chemical Society.

Unexpected Relationships between Structure and Function in α,β-Peptides: Antimicrobial Foldamers with Heterogeneous Backbones

S. Gellman, B. Weisblum, M. Schmitt, 2004 .

Interplay among Folding, Sequence, and Lipophilicity in the Antibacterial and Hemolytic Activities of α/β-Peptides

S. Gellman, B. Weisblum, M. Schmitt, 2007 .

Erythromycin-inducible Resistance in Staphylococcus aureus: Survey of Antibiotic Classes Involved

B. Weisblum, V. Demohn, 1969, Journal of bacteriology.

Improved small-molecule macroarray platform for the rapid synthesis and discovery of antibacterial chalcones.

B. Weisblum, H. Blackwell, Matthew D. Bowman, 2011, ACS combinatorial science.

23S rRNA domain V, a fragment that can be specifically methylated in vitro by the ErmSF (TlrA) methyltransferase

B. Weisblum, H. Jin, D. Kovalic, 1994, Journal of bacteriology.

Macrolide resistance

B. Weisblum, 1998, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.

[17] Direct cloning of DNA fragments generated by PCR

B. Weisblum, D. Kovalic, 1995 .

Interplay among subunit identity, subunit proportion, chain length, and stereochemistry in the activity profile of sequence-random peptide mixtures.

Zvi Hayouka, Saswata Chakraborty, S. Gellman, 2013, Journal of the American Chemical Society.

Biocidal activity of polystyrenes that are cationic by virtue of protonation.

D. M. Lynn, S. Gellman, B. Weisblum, 2004 .

Mimicry of antimicrobial host-defense peptides by random copolymers.

S. Gellman, B. Weisblum, R. Epand, 2007, Journal of the American Chemical Society.

Deoxyribonucleic acid sequence common to staphylococcal and streptococcal plasmids which specify erythromycin resistance

B. Weisblum, S. Halling, S. Holder, 1979, Journal of bacteriology.

Mutant of Staphylococcus aureus with Lincomycin- and Carbomycin-Inducible Resistance to Erythromycin

B. Weisblum, T. Tanaka, 1974, Antimicrobial Agents and Chemotherapy.

Inducible resistance to macrolides, lincosamides and streptogramin type B antibiotics: the resistance phenotype, its biological diversity, and structural elements that regulate expression--a review.

B. Weisblum, 1985, The Journal of antimicrobial chemotherapy.

Erythromycin-induced ribosome stall in the ermA leader: a barricade to 5'-to-3' nucleolytic cleavage of the ermA transcript

B. Weisblum, P. Sandler, 1989, Journal of bacteriology.

Messenger RNA from Staphylococcus aureus that specifies macrolide-lincosamide-streptogramin resistance. Demonstration of its conformations and of the leader peptide it encodes.

M. Mayford, B. Weisblum, 1985, Journal of molecular biology.

Subunit localization studies of antibiotic inhibitors of protein synthesis.

B. Weisblum, F. Chang, C. Siddhikol, 1969, Biochimica et biophysica acta.

Inhibition of DNA replication in Staphylococcus aureus by tegaserod

S. Falk, B. Weisblum, Christopher J Lacriola, 2017, The Journal of Antibiotics.

Evidence for phenylalanine zipper-mediated dimerization in the X-ray crystal structure of a magainin 2 analogue.

S. Gellman, B. Weisblum, K. Forest, 2013, Journal of the American Chemical Society.

C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities.

S. Gellman, B. Weisblum, S. Stahl, 2012, Biomacromolecules.

Functionally Diverse Nylon-3 Copolymers from Readily Accessible β-Lactams.

S. Gellman, B. Weisblum, S. Stahl, 2012, ACS macro letters.

Plasmid copy number control: isolation and characterization of high-copy-number mutants of plasmid pE194

D. Dubnau, B. Weisblum, M. Y. Graham, 1979, Journal of bacteriology.

Opening Lecture Altered Methylation of Ribosomal RNA in Erythromycin-resistant Staphylococcus Aureus

B. Weisblum, 1975 .

Altered Methylation of Ribosomal RNA in Erythromycin-Resistant Staphylococcus Aureus

B. Weisblum, 1975 .

Structure of an inducibly methylatable nucleotide sequence in 23S ribosomal ribonucleic acid from erythromycin-resistant Staphylococcus aureus.

B. Weisblum, C. Lai, J. Dahlberg, 1973, Biochemistry.

Erythromycin-Inducible Resistance in Staphylococcus aureus: Requirements for Induction

B. Weisblum, C. Lai, V. Demohn, 1971, Journal of bacteriology.

Thiostrepton, an Inhibitor of50SRibosome Subunit Function

B. Weisblum, V. Demohn, 1970 .

Thiostrepton, an Inhibitor of 50S Ribosome Subunit Function

B. Weisblum, V. Demohn, 1970 .

Lincomycin, an inhibitor of aminoacyl sRNA binding to ribosomes.

B. Weisblum, C. Sih, F. Chang, 1966, Proceedings of the National Academy of Sciences of the United States of America.

The specificity of lincomycin binding to ribosomes.

B. Weisblum, F. Chang, 1967, Biochemistry.

West Nile virus methyltransferase domain interacts with protein kinase G

S. Falk, R. Kuhn, R. Striker, 2013, Virology Journal.

Peptide analogues of the VanS catalytic center inhibit VanR binding to its cognate promoter.

B. Weisblum, B. Kay, A. Ulijasz, 2000, Biochemistry.

Affinity adsorbent based on combinatorial phage display peptides that bind α-cobratoxin

B. Weisblum, W. Byeon, 2004 .

Back to Camelot: defining the specific role of tRNA in protein synthesis.

B. Weisblum, Bernard Weisblum, 1999, Trends in biochemical sciences.

Pneumococcus resistant to erythromycin and lincomycin.

B. Weisblum, 1967, Lancet.

Erythromycin resistance by ribosome modification

B. Weisblum, 1995, Antimicrobial agents and chemotherapy.

Modulation of Erm Methyltransferase Activity by Peptides Derived from Phage Display

B. Weisblum, R. Giannattasio, 2000, Antimicrobial Agents and Chemotherapy.

Essential role of endogenously synthesized tylosin for induction of ermSF in Streptomyces fradiae

B. Weisblum, E. Memili, 1997, Antimicrobial agents and chemotherapy.

Induction of ermSV by 16-membered-ring macrolide antibiotics

B. Weisblum, S. Kamimiya, S. Kamimiya, 1997, Antimicrobial agents and chemotherapy.

A family of r-determinants in Streptomyces spp. that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibiotics

B. Weisblum, Y. Fujisawa, 1981, Journal of bacteriology.

23S ribosomal ribonucleic acid of macrolide-producing streptomycetes contains methylated adenine

B. Weisblum, M. Y. Graham, Madge Yang GRAHAMt, 1979, Journal of bacteriology.

Systematic difference in the methylation of ribosomal ribonucleic acid from gram-positive and gram-negative bacteria

B. Weisblum, T. Tanaka, 1975, Journal of bacteriology.

Alteration of 23 S ribosomal RNA and erythromycin-induced resistance to lincomycin and spiramycin in Staphylococcus aureus.

B. Weisblum, M. Nomura, C. Lai, 1973, Journal of molecular biology.

Construction and characterization of a chimeric plasmid composed of DNA Pfrom Escherichia coli and Drosophila melanogaster.

T. Tanaka, B. Weisblum, R. Inman, 1975, Biochemistry.

Biocidal activity of polystyrenes that are cationic by virtue of protonation.

D. M. Lynn, S. Gellman, B. Weisblum, 2004, Organic letters.

Construction ofa Colicin E1-RFactor Composite Plasmid In Vitro: MeansforAmplification ofDeoxyribonucleic Acid

B. Weisblum, Teruo Tanaka, 1975 .

cleavage of the ermA transcript. ermA leader: a barricade to 5'-to-3' nucleolytic Erythromycin-induced ribosome stall in the

B. Weisblum, P. Sandler, 2013 .

Ribosome Stall intheermALeader: a Barricade to5'-to-3' Nucleolytic Cleavage oftheermATranscript

B. Weisblum, P. Sandler, 1989 .

licheniformis.determinant from Bacillus macrolide-lincosamide-streptogramin B Transcriptional attenuation control of ermK, a

B. Weisblum, J. Kwak, E. Choi, 2013 .

Erythromycin-induced stabilization of ermA messenger RNA in Staphylococcus aureus and Bacillus subtilis.

B. Weisblum, P. Sandler, 1988, Journal of molecular biology.

Quinacrine, a chromosome stain specific for deoxyadenylate-deoxythymidylaterich regions in DNA.

B. Weisblum, P. de Haseth, P. D. Haseth, 1972, Proceedings of the National Academy of Sciences of the United States of America.

Antibiotic inhibitors of the bacterial ribosome

B. Weisblum, J. Davies, 1968, Bacteriological reviews.

An analysis of arginine codon multiplicity in rabbit hemoglobin.

D. Söll, B. Weisblum, R. Bock, 1967, Journal of molecular biology.

Fluorometric properties of the bibenzimidazole derivative hoechst 33258, a fluorescent probe specific for AT concentration in chromosomal DNA

B. Weisblum, Elise Haenssler, 2004, Chromosoma.

Aptamer Displacement Screen for Flaviviral RNA Methyltransferase Inhibitors

S. Falk, B. Weisblum, Shaun P. Falk, 2014, Journal of biomolecular screening.

Replication genes of plasmid pE194-cop and repF: transcripts and encoded proteins

B. Weisblum, W. Byeon, 1990, Journal of bacteriology.

Use of parallel synthesis to probe structure-activity relationships among 12-helical beta-peptides: evidence of a limit on antimicrobial activity.

S. Gellman, B. Weisblum, E. A. Porter, 2005, Journal of the American Chemical Society.

Comparison of JC and BK Human Papovaviruses with Simian Virus 40: Restriction Endonuclease Digestion and Gel Electrophoresis of Resultant Fragments

B. Weisblum, B. Padgett, D. Walker, 1974, Journal of virology.

Differential Assay for High-Throughput Screening of Antibacterial Compounds

S. Falk, B. Weisblum, A. Ulijasz, 2007, Journal of biomolecular screening.

Mimicry of host-defense peptides by unnatural oligomers: antimicrobial beta-peptides.

S. Gellman, B. Weisblum, E. A. Porter, 2002, Journal of the American Chemical Society.

Antibiotics: Non-haemolytic β-amino-acid oligomers

S. Gellman, Hee-Seung Lee, B. Weisblum, 2000, Nature.

Electrostatic versus steric effects in peptidomimicry: synthesis and secondary structure analysis of gramicidin S analogues with (E)-alkene peptide isosteres.

P. Wipf, Jingbo Xiao, B. Weisblum, 2005, Journal of the American Chemical Society.

Inhibition by thiostrepton of the formation of a ribosome‐bound guanine nucleotide complex

B. Weisblum, V. Demohn, 1970, FEBS letters.

Thiostrepton, an Inhibitor of 50S Ribosome Subunit Function

B. Weisblum, V. Demohn, 1970, Journal of bacteriology.

A vancomycin-inducible lacZ reporter system in Bacillus subtilis: induction by antibiotics that inhibit cell wall synthesis and by lysozyme

B. Weisblum, A. Ulijasz, A. Grenader, 1996, Journal of bacteriology.

Tolerance of acyclic residues in the beta-peptide 12-helix: access to diverse side-chain arrays for biological applications.

S. Gellman, B. Weisblum, J. D. Fisk, 2002, Journal of the American Chemical Society.

Antifungal Activity from 14-Helical β-Peptides

Amy J. Karlsson, S. Gellman, B. Weisblum, 2006 .

Structure–Activity Relationships among Antifungal Nylon-3 Polymers: Identification of Materials Active against Drug-Resistant Strains of Candida albicans

Sean P. Palecek, Amy J. Karlsson, S. Gellman, 2014, Journal of the American Chemical Society.

Interplay among folding, sequence, and lipophilicity in the antibacterial and hemolytic activities of alpha/beta-peptides.

S. Gellman, B. Weisblum, M. Schmitt, 2007, Journal of the American Chemical Society.

On the role of soluble ribonucleic acid in coding for amino acids.

S. Benzer, B. Weisblum, F. Lipmann, 1962, Proceedings of the National Academy of Sciences of the United States of America.

Screen for Inducers of Autolysis in Bacillus subtilis

B. Weisblum, J. Noah, Shaun P. Falk, 2010, Antimicrobial Agents and Chemotherapy.

Antibiotic Inhibitors of the Bacterial Ribosome

B. Weisblum, J. Davies, 1968, Bacteriological reviews.

Phosphorylation of the Streptococcus pneumoniae cell wall biosynthesis enzyme MurC by a eukaryotic-like Ser/Thr kinase.

B. Weisblum, Shaun P. Falk, 2013, FEMS microbiology letters.

Phosphorylation of the RitR DNA‐binding domain by a Ser–Thr phosphokinase: implications for global gene regulation in the streptococci

B. Weisblum, A. Ulijasz, Shaun P. Falk, 2009, Molecular microbiology.

Rice-induced secondary metabolite gene expression in Aspergillus nidulans.

B. Weisblum, Christopher J Lacriola, Shaun P. Falk, 2020, Journal of industrial microbiology & biotechnology.

CHANGES IN PANCREATIC ACINAR CELLS DURING PROTEIN DEPRIVATION

B. Weisblum, P. Fitzgerald, L. Herman, 1962, The Journal of cell biology.

Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance

S. Horinouchi, B. Weisblum, 1982, Journal of bacteriology.

Aminoglycoside-modifying enzyme of an antibiotic-producing bacterium acts as a determinant of antibiotic resistance in Escherichia coli.

B. Weisblum, P. Courvalin, J. Davies, 1977, Proceedings of the National Academy of Sciences of the United States of America.

General method for direct cloning of DNA fragments generated by the polymerase chain reaction.

B. Weisblum, J. Kwak, D. Kovalic, 1991, Nucleic acids research.

A complex attenuator regulates inducible resistance to macrolides, lincosamides, and streptogramin type B antibiotics in Streptococcus sanguis

S. Horinouchi, B. Weisblum, W. Byeon, 1983, Journal of bacteriology.

Nucleotide sequence and functional map of pE194, a plasmid that specifies inducible resistance to macrolide, lincosamide, and streptogramin type B antibodies

S. Horinouchi, B. Weisblum, 1982, Journal of bacteriology.

Why Centric Regions of Quinacrine-treated Mouse Chromosomes show Diminished Fluorescence

B. Weisblum, 1973, Nature.

Preparation and properties of iodinated angiotensins.

B. Weisblum, T. Goodfriend, S. Y. Lin, 1970, Biochemical pharmacology.

Insights into erythromycin action from studies of its activity as inducer of resistance

B. Weisblum, B Weisblum, 1995, Antimicrobial agents and chemotherapy.

Posttranscriptional modification of mRNA conformation: mechanism that regulates erythromycin-induced resistance.

S. Horinouchi, B. Weisblum, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Mode of Action of Streptolydigin

B. Weisblum, C. Siddhikol, J. W. Erbstoeszer, 1969, Journal of bacteriology.

The control region for erythromycin resistance: Free energy changes related to induction and mutation to constitutive expression

S. Horinouchi, B. Weisblum, 2004, Molecular and General Genetics MGG.

Fluorescent probes of chromosomal DNA structure: three classes of acridines.

B. Weisblum, 1974, Cold Spring Harbor symposia on quantitative biology.

A phsyical basis for degeneracy in the amino acid code.

S. Benzer, B. Weisblum, R. W. Holley, 1962, Proceedings of the National Academy of Sciences of the United States of America.

Inducible erythromycin resistance in bacteria.

B. Weisblum, 1984, British medical bulletin.

Quinacrine , A Chromosome Stain Specific for Deoxyadenylate-Deoxythymidylate-Rich Regions in DNA ( double-stranded DNA / heterochromatin / proflavine / acridine orange / fluorescence )

B. Weisblum, P. L. D. Haseth, P. D. Haseth, 2022 .

Comparison of JC and BK human papovaviruses with simian virus 40: DNA homology studies

B. Weisblum, B. Padgett, J. Osborn, 1976, Journal of virology.

Transcriptional attenuation control of ermK, a macrolide-lincosamide-streptogramin B resistance determinant from Bacillus licheniformis

B. Weisblum, J. Kwak, E. Choi, 1991, Journal of bacteriology.

ermC leader peptide. Amino acid sequence critical for induction by translational attenuation.

M. Mayford, B. Weisblum, Mark Mayford, 1989, Journal of molecular biology.

Differential Efficiency of Induction by Macrolide-

B. Weisblum, And, '. Markmayford, 2022 .

The ermC leader peptide: amino acid alterations leading to differential efficiency of induction by macrolide-lincosamide-streptogramin B antibiotics

M. Mayford, B. Weisblum, 1990, Journal of bacteriology.

Translational attenuation control of ermSF, an inducible resistance determinant encoding rRNA N-methyltransferase from Streptomyces fradiae

B. Weisblum, S. Kamimiya, 1988, Journal of bacteriology.

Tuning the Biological Activity Profile of Antibacterial Polymers via Subunit Substitution Pattern

S. Gellman, B. Weisblum, Runhui Liu, 2014, Journal of the American Chemical Society.

Regulation of Iron Transport in Streptococcus pneumoniae by RitR, an Orphan Response Regulator

J. Glasner, B. Weisblum, A. Ulijasz, 2004, Journal of bacteriology.

Ternary Nylon-3 Copolymers as Host-Defense Peptide Mimics: Beyond Hydrophobic and Cationic Subunits

Gerard C. L. Wong, Kristyn S. Masters, Zvi Hayouka, 2014, Journal of the American Chemical Society.

Screen for Agents That Induce Autolysis in Bacillus subtilis

B. Weisblum, Christopher J Lacriola, Shaun P. Falk, 2012, Antimicrobial Agents and Chemotherapy.

Phosphorylation of yellow fever virus NS5 alters methyltransferase activity.

R. Striker, B. Weisblum, S. Hoover, 2008, Virology.

Bacterial 2-Component Signal Transduction Systems: A Fluorescence Polarization Screen for Response Regulator-Protein Binding

B. Weisblum, A. Ulijasz, M. Erickson, 2005, Journal of biomolecular screening.

Regulator-Protein Binding Bacterial 2-Component Signal Transduction Systems: A Fluorescence Polarization Screen for Response

B. Weisblum, A. Ulijasz, M. Erickson, 2013 .

Screening for compounds that affect the interaction between bacterial two-component signal transduction response regulator protein and cognate promoter DNA.

B. Weisblum, A. Ulijasz, M. Erickson, 2008, Methods in molecular medicine.

Hydrophobic core repacking in a coiled-coil dimer via phage display: insights into plasticity and specificity at a protein-protein interface.

S. Gellman, J. Lai, B. Weisblum, 2004, Journal of the American Chemical Society.

Post-transcriptional Regulation of Chloramphenicol Acetyl Transferase

B. Weisblum, W. Byeon, 1984, Journal of bacteriology.

Unexpected relationships between structure and function in alpha,beta-peptides: antimicrobial foldamers with heterogeneous backbones.

S. Gellman, B. Weisblum, M. Schmitt, 2004, Journal of the American Chemical Society.

Antifungal activity from 14-helical beta-peptides.

Amy J. Karlsson, S. Gellman, B. Weisblum, 2006, Journal of the American Chemical Society.

Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon-3 Polymers

S. Gellman, B. Weisblum, E. Chapman, 2021, Journal of the American Chemical Society.

Trisubstituted (E)-alkene dipeptide isosteres as beta-turn promoters in the gramicidin S cyclodecapeptide scaffold.

P. Wipf, Jingbo Xiao, B. Weisblum, 2006, Organic letters.

N-Methyl transferase of Streptomyces erythraeus that confers resistance to the macrolide-lincosamide-streptogramin B antibiotics: amino acid sequence and its homology to cognate R-factor enzymes from pathogenic bacilli and cocci.

B. Weisblum, H. Uchiyama, 1985, Gene.

Synthetic Polymers Active against Clostridium difficile Vegetative Cell Growth and Spore Outgrowth

S. Gellman, B. Weisblum, Runhui Liu, 2014, Journal of the American Chemical Society.

Conformational alterations in the ermC transcript in vivo during induction.

M. Mayford, B. Weisblum, 1989, The EMBO journal.

Retention of Native Quaternary Structure in Racemic Melittin Crystals.

S. Gellman, B. Weisblum, K. Forest, 2019, Journal of the American Chemical Society.

Nylon-3 polymers active against drug-resistant Candida albicans biofilms.

S. Gellman, B. Weisblum, Runhui Liu, 2015, Journal of the American Chemical Society.

Nylon-3 polymers with selective antifungal activity.

S. Gellman, B. Weisblum, Runhui Liu, 2013, Journal of the American Chemical Society.

C-terminal functionalization of nylon-3 polymers: effects of C-terminal groups on antibacterial and hemolytic activities.

S. Gellman, B. Weisblum, S. Stahl, 2012, Biomacromolecules.

A DEMONSTRATION OF CODING DEGENERACY FOR LEUCINE IN THE SYNTHESIS OF PROTEIN.

S. Benzer, B. Weisblum, F. Gonano, 1965, Proceedings of the National Academy of Sciences of the United States of America.

Structure-activity relationships among random nylon-3 copolymers that mimic antibacterial host-defense peptides.

S. Gellman, B. Weisblum, B. Mowery, 2009, Journal of the American Chemical Society.

Roles of salt and conformation in the biological and physicochemical behavior of protegrin-1 and designed analogues: correlation of antimicrobial, hemolytic, and lipid bilayer-perturbing activities.

S. Gellman, J. Lai, B. Weisblum, 2006, Biochemistry.

Quasiracemate Crystal Structures of Magainin 2 Derivatives Support the Functional Significance of the Phenylalanine Zipper Motif.

S. Gellman, K. Satyshur, B. Weisblum, 2015, Journal of the American Chemical Society.