J. Tower

发表

Three-dimensional tracking and behaviour monitoring of multiple fruit flies

S. Tavaré, M. Arbeitman, S. Nuzhdin, 2013, Journal of The Royal Society Interface.

Jie Shen, John Tower, J. Tower, 2019, Ageing Research Reviews.

Buffering of Genetic Regulatory Networks in Drosophila melanogaster

L. León-Novelo, S. Nuzhdin, J. Tower, 2016, Genetics.

Functionally distinct, sequence-specific replicator and origin elements are required for Drosophila chorion gene amplification.

J. Tower, L. Lu, H. Zhang, 2001, Genes & development.

Developmental gene amplification and origin regulation.

J. Tower, 2004, Annual review of genetics.

Preferential transposition of Drosophila P elements to nearby chromosomal sites.

A. Spradling, G. Karpen, J. Tower, 1993, Genetics.

Preferential transposition of aDrosophila P element to the corresponding region of the homologous chromosome

J. Tower, R. Kurapati, 1994, Molecular and General Genetics MGG.

Conditional Switches for Extracellular Matrix Patterning in Drosophila melanogaster

J. Tower, Arvinder Khokhar, Nan Chen, 2008, Genetics.

The progesterone antagonist mifepristone/RU486 blocks the negative effect on life span caused by mating in female Drosophila

J. Tower, M. Salomon, G. Landis, 2015, Aging.

Using GFP Video to Track 3D Movement and Conditional Gene Expression in Free-Moving Flies

S. Tavaré, R. Ardekani, J. Tower, 2012, PloS one.

Sex-Specific Aging in Flies, Worms, and Missing Great-Granddads

C. Finch, J. Tower, 2014, Cell.

Aging, MnSOD, and hormesis mechanisms converge on liver mUPR

J. Tower, Jie Shen, 2013, Cell cycle.

Metabolic Signatures of Life Span Regulated by Mating, Sex Peptide and Mifepristone/RU486 in Female Drosophila melanogaster.

D. Promislow, J. Tower, Jie Shen, 2020, The journals of gerontology. Series A, Biological sciences and medical sciences.

The genetic architecture of aging: Sexual antagonistic plieotropy of p53 and foxo

J. Tower, 2010, Cell cycle.

Models of Replicator Proliferation Involving Differential Replicator Subunit Stability

J. Tower, Zewei Li, Runhe Lyu, 2018, Origins of Life and Evolution of Biospheres.

Sex-Specific Gene Expression and Life Span Regulation

J. Tower, 2017, Trends in Endocrinology & Metabolism.

Polymerase III transcription factor B activity is reduced in extracts of growth-restricted cells

J. Tower, B. Sollner-Webb, 1988 .

Polymerase III transcription factor B activity is reduced in extracts of growth-restricted cells

J. Tower, B. Sollner-Webb, 1988, Molecular and cellular biology.

Simon Tavaré, Junsheng Yang, Diana Abdueva, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Multiple Metazoan Life-span Interventions Exhibit a Sex-specific Strehler–Mildvan Inverse Relationship Between Initial Mortality Rate and Age-dependent Mortality Rate Acceleration

J. Tower, Jie Shen, G. Landis, 2017, The journals of gerontology. Series A, Biological sciences and medical sciences.

Erratum to: Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

S. Tavaré, C. Curtis, J. Tower, 2016, Genome Biology.

Assessing senescence in Drosophila using video tracking.

S. Tavaré, R. Ardekani, J. Tower, 2013, Methods in molecular biology.

Simultaneous tracking of fly movement and gene expression using GFP

S. Tavaré, J. Tower, Dhruv Grover, 2008, BMC biotechnology.

Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

S. Tavaré, C. Curtis, J. Tower, 2007, Genome Biology.

Ubiquitin over-expression phenotypes and ubiquitin gene molecular misreading during aging in Drosophila melanogaster

J. Tower, G. Landis, N. Hoe, 2011, Aging.

There's a problem in the furnace.

J. Tower, 2004, Science of aging knowledge environment : SAGE KE.

Transcription of mouse rDNA is regulated by an activated subform of RNA polymerase I

J. Tower, B. Sollner-Webb, B. Sollner‐Webb, 1987, Cell.

A complex control region of the mouse rRNA gene directs accurate initiation by RNA polymerase I

J. Tower, K. Miller, B. Sollner-Webb, 1985, Molecular and cellular biology.

Drosophila foxo acts in males to cause sexual-dimorphism in tissue-specific p53 life span effects

J. Tower, Jie Shen, 2010, Experimental Gerontology.

A screen of apoptosis and senescence regulatory genes for life span effects when over-expressed in Drosophila

S. Tavaré, C. Curtis, J. Tower, 2009, Aging.

The murmur of old broken heartstrings.

J. Tower, 2006, Cell metabolism.

Genetics of 51D-52A, a region containing several maternal-effect genes and two maternal-specific transcripts in Drosophila.

D. Otteson, J. Tower, R. Ludwiczak, 1990, Genetics.

Mifepristone Increases Life Span in Female Drosophila Without Detectable Antibacterial Activity

J. Tower, G. Landis, Luke Riggan, 2022, Frontiers in Aging.

An RNA polymerase I promoter located in the CHO and mouse ribosomal DNA spacers: functional analysis and factor and sequence requirements

J. Tower, B. Sollner-Webb, K. Dougherty, 1989, Molecular and cellular biology.

Lactobacillus plantarum gives Drosophila the grow signal.

J. Tower, 2011, Cell metabolism.

A screen of small molecule and genetic modulators of life span in female Drosophila identifies etomoxir, RH5849 and unanticipated temperature effects

J. Tower, Sebastian Ko, Gary N Landis, 2022, Fly.

Sex-specific regulation of aging and apoptosis

John Tower, J. Tower, 2006, Mechanisms of Ageing and Development.

Transcription of cloned eukaryotic ribosomal RNA genes.

J. Tower, B. Sollner-Webb, Barbara Sollner-Webb, 1986, Annual review of biochemistry.

FLP Recombinase-Mediated Induction of Cu/Zn-Superoxide Dismutase Transgene Expression Can Extend the Life Span of Adult Drosophila melanogaster Flies

J. Tower, Jingtao Sun, 1999, Molecular and Cellular Biology.

Programmed cell death in aging

J. Tower, 2015, Ageing Research Reviews.

The wright stuff: reimagining path analysis reveals novel components of the sex determination hierarchy in drosophila melanogaster

John Tower, Lauren M. McIntyre, Michelle N. Arbeitman, 2015, BMC Systems Biology.

Muscle-specific expression of Drosophila hsp70 in response to aging and oxidative stress.

Erik T. Bieschke, J. Tower, E. Bieschke, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Mifepristone Increases Life Span of Virgin Female Drosophila on Regular and High-fat Diet Without Reducing Food Intake

P. Kapahi, D. Promislow, J. Tower, 2021, Frontiers in Genetics.

A transcriptional insulator element, the su(Hw) binding site, protects a chromosomal DNA replication origin from position effects

J. Tower, L. Lu, John Tower, 1997, Molecular and cellular biology.

Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster.

J. Tower, T. Bradley, Donna G. Folk, 2002, Genetics.

Mitochondrial maintenance failure in aging and role of sexual dimorphism.

J. Tower, 2015, Archives of biochemistry and biophysics.

Transgenic methods for increasing Drosophila life span

J. Tower, 2000, Mechanisms of Ageing and Development.

Expression of hsp22 and hsp70 transgenes is partially predictive of drosophila survival under normal and stress conditions.

J. Tower, Junsheng Yang, 2009, The journals of gerontology. Series A, Biological sciences and medical sciences.

Expression of hsp 22 and hsp 70 Transgenes Is Partially Predictive of Drosophila Survival Under Normal and Stress Conditions

J. Tower, Junsheng Yang, 2022 .

Impact papers on aging in 2009 Citation

L. Donehower, M. Gorospe, R. DePinho, 2022 .

Impact papers on aging in 2009

L. Donehower, M. Gorospe, R. DePinho, 2010, Aging.

Gene expression changes in response to aging compared to heat stress, oxidative stress and ionizing radiation in Drosophila melanogaster

J. Tower, Jie Shen, G. Landis, 2012, Aging.

Analysis of Drosophila melanogaster Lifespan.

J. Tower, G. Landis, Devon V. Doherty, 2020, Methods in molecular biology.

Behavioral and molecular markers of death in Drosophila melanogaster

J. Tower, Prathamesh Sancheti, A. Varma, 2019, Experimental Gerontology.

Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster

J. Tower, K. Tominaga, O. Pereira-smith, 2010, Experimental Gerontology.

Superoxide dismutase evolution and life span regulation

J. Tower, G. Landis, 2005, Mechanisms of Ageing and Development.

In vivo assay and modelling of protein and mitochondrial turnover during aging

J. Tower, Hans S. Bell, 2021, Fly.

Drosophila melanogaster p53 has developmental stage-specific and sex-specific effects on adult life span indicative of sexual antagonistic pleiotropy

S. Tavaré, C. Curtis, J. Tower, 2009, Aging.

The effects of reduced pH on chemical alarm signalling in ostariophysan fishes

J. Tower, Grant E. Brown, J. C. Adrian, 2002 .

Increased internal and external bacterial load during Drosophila aging without life-span trade-off.

J. Tower, S. Finkel, P. Webster, 2007, Cell metabolism.

The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress

Sarah Wong, John Tower, L. C. Pomatto, 2017, Current Biology.

Adult-specific over-expression of the Drosophila genes magu and hebe increases life span and modulates late-age female fecundity

John Tower, J. Tower, Yishi Li, 2009, Molecular Genetics and Genomics.

Mifepristone/RU486 acts in Drosophila melanogaster females to counteract the life span-shortening and pro-inflammatory effects of male Sex Peptide

Jie Shen, John Tower, J. Tower, 2017, Biogerontology.

Sexual dimorphism in oxidant-induced adaptive homeostasis in multiple wild-type D. melanogaster strains.

L. C. Pomatto, K. Davies, Sarah Wong, 2017, Archives of biochemistry and biophysics.

Factors and nucleotide sequences that direct ribosomal DNA transcription and their relationship to the stable transcription complex

J. Tower, V. Culotta, B. Sollner-Webb, 1986, Molecular and cellular biology.

Identifying sexual differentiation genes that affect Drosophila life span

J. Tower, Jie Shen, G. Landis, 2009, BMC geriatrics.

Hsps and aging

J. Tower, 2009, Trends in Endocrinology & Metabolism.

Aging-specific expression of Drosophila hsp22.

J. Tower, V. King, Vanessa King, 1999, Developmental biology.

Sex differences in the response to oxidative and proteolytic stress

L. C. Pomatto, K. Davies, J. Tower, 2020, Redox biology.

Sexual Dimorphism and Aging Differentially Regulate Adaptive Homeostasis

K. Davies, L. C. Pomatto, J. Tower, 2018, The journals of gerontology. Series A, Biological sciences and medical sciences.

Natural variation of gene models in Drosophila melanogaster

Alexander V. Favorov, M. Gelfand, S. Nuzhdin, 2015, BMC Genomics.

Stem cell aging in the Drosophila ovary

J. Tower, Yishi Li, M. Waskar, 2005, AGE.

The genetics of gender and life span

John Tower, M. Arbeitman, J. Tower, 2009, Journal of biology.

Heat shock proteins and Drosophila aging

John Tower, J. Tower, 2011, Experimental Gerontology.

The k43 gene, required for chorion gene amplification and diploid cell chromosome replication, encodes the Drosophila homolog of yeast origin recognition complex subunit 2.

A. Spradling, J. Tower, R. Kelley, 1997, Proceedings of the National Academy of Sciences of the United States of America.

Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span

J. Tower, J. Molitor, Jingtao Sun, 2004, Mechanisms of Ageing and Development.

Hydrogen Peroxide Stimulates Activity and Alters Behavior in Drosophila melanogaster

Simon Tavaré, Dhruv Grover, John Tower, 2009, PloS one.

Stress and stem cells

J. Tower, 2012, Wiley interdisciplinary reviews. Developmental biology.

A conserved role for the 20S proteasome and Nrf2 transcription factor in oxidative stress adaptation in mammals, Caenorhabditis elegans and Drosophila melanogaster

K. Davies, J. Tower, Andrew M Pickering, 2013, Journal of Experimental Biology.

Oxidative stress adaptation with acute, chronic, and repeated stress.

J. Tower, Andrew M Pickering, Lesya Vojtovich, 2013, Free radical biology & medicine.

Sex-specific adaptive homeostasis in D. melanogaster depends on increased proteolysis by the 20S Proteasome: Data-in-Brief

L. C. Pomatto, K. Davies, Sarah Wong, 2018, Data in brief.

Genetic Manipulation of Life Span in Drosophila melanogaster

J. Tower, Daniel Ford, 2005 .

Aging, Somatic Maintenance, and Genomic Stability in Drosophila melanogaster

J. Tower, 2003 .

A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes

J. Tower, G. Landis, D. Bhole, 2003, Genome Biology.

Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster

M. Rose, J. Tower, G. Landis, 2002, Genome Biology.

Aging mechanisms in fruit flies

J. Tower, 1996 .

The age- and sex-specific decline of the 20s proteasome and the Nrf2/CncC signal transduction pathway in adaption and resistance to oxidative stress in Drosophila melanogaster

L. C. Pomatto, K. Davies, Sarah Wong, 2017, Aging.

Incorporating antagonistic pleiotropy into models for molecular replicators

Tianjiao Qu, Peter Calabrese, Pratik Singhavi, 2020, Biosyst..

Sequence requirements for function of the Drosophila chorion gene locus ACE3 replicator and ori-β origin elements

J. Tower, Hongjun Zhang, 2004, Development.

The Drosophila chiffon gene is required for chorion gene amplification, and is related to the yeast Dbf4 regulator of DNA replication and cell cycle.

J. Tower, G. Landis, John Tower, 1999, Development.

Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycyline or RU486/Mifepristone

J. Tower, G. Landis, N. Hoe, 2007, Experimental Gerontology.

Doxycycline-induced transgene expression during Drosophila development and aging

Erik T. Bieschke, J. Tower, E. Bieschke, 1998, Molecular and General Genetics MGG.

Simultaneous tracking of movement and gene expression in multiple Drosophila melanogaster flies using GFP and DsRED fluorescent reporter transgenes

Simon Tavaré, Junsheng Yang, Dhruv Grover, 2009, BMC Research Notes.

Doxycycline-regulated over-expression of hsp22 has negative effects on stress resistance and life span in adult Drosophila melanogaster

J. Tower, D. Bhole, M. Allikian, 2004, Mechanisms of Ageing and Development.

Drosophila flies in the face of aging.

J. Tower, 2019, The journals of gerontology. Series A, Biological sciences and medical sciences.

Conditional inhibition of autophagy genes in adult Drosophila impairs immunity without compromising longevity

J. Tower, S. Finkel, Chunli Ren, 2009, Experimental Gerontology.

Increased hsp22 RNA levels in Drosophila lines genetically selected for increased longevity.

M. Rose, J. Tower, R. Kurapati, 2000, The journals of gerontology. Series A, Biological sciences and medical sciences.

Variegated expression of Hsp22 transgenic reporters indicates cell-specific patterns of aging in Drosophila oenocytes.

J. Tower, G. Landis, Yuanyue Sun, 2014, The journals of gerontology. Series A, Biological sciences and medical sciences.

High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span.

J. Tower, G. Landis, D. Bhole, 2001, Genetics.

Sequence requirements for upregulated expression of Drosophila hsp70 transgenes during aging☆

J. Tower, J. C. Wheeler, V. King, 1999, Neurobiology of Aging.

The Proteasome Beta 5 subunit is essential for sexually divergent adaptive homeostatic responses to oxidative stress in D. melanogaster.

K. Davies, L. C. Pomatto, Christina Sisliyan, 2017, Free radical biology & medicine.

O fly, where art thou?

Simon Tavaré, John Tower, Dhruv Grover, 2008, Journal of The Royal Society Interface.

Programmed cell death and apoptosis in aging and life span regulation.

J. Tower, Jie Shen, 2009, Discovery medicine.

Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

S. Tavaré, C. Curtis, J. Tower, 2007, Genome Biology.

11 Yeast, a Feast: The Fruit Fly Drosophila as a Model Organism for Research into Aging

L. Partridge, J. Tower, 2008 .