Ye Fang

发表

G protein-coupled receptor microarrays for drug discovery.

J. Lahiri, Ye Fang, L. Picard, 2003, Drug discovery today.

The development of label-free cellular assays for drug discovery

Ye Fang, 2011, Expert opinion on drug discovery.

Ligand–receptor interaction platforms and their applications for drug discovery

Ye Fang, Ye Fang, 2012, Expert opinion on drug discovery.

Optical biosensor provides insights for bradykinin B2 receptor signaling in A431 cells

Ye Fang, Guangshan Li, Jinlin Peng, 2005, FEBS letters.

Compound annotation with real time cellular activity profiles to improve drug discovery

Ye Fang, 2016, Expert opinion on drug discovery.

Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells.

Ye Fang, Guangshan Li, A. Ferrie, 2007, Journal of pharmacological and toxicological methods.

Label‐free optical biosensor for ligand‐directed functional selectivity acting on β2 adrenoceptor in living cells

Ye Fang, A. Ferrie, 2008, FEBS letters.

Probing cancer signaling with resonant waveguide grating biosensors

Ye Fang, 2010, Expert opinion on drug discovery.

Discovery of 2-(4-Methylfuran-2(5H)-ylidene)malononitrile and Thieno[3,2-b]thiophene-2-carboxylic Acid Derivatives as G Protein-Coupled Receptor 35 (GPR35) Agonists

Ye Fang, M. He, Weijun Niu, 2011, Journal of medicinal chemistry.

Label-free integrative pharmacology on-target of drugs at the β2-adrenergic receptor

Ye Fang, A. Ferrie, Haiyan Sun, 2011, Scientific reports.

Label-Free Receptor Assays.

Ye Fang, 2011, Drug discovery today. Technologies.

Label-Free Biosensors for Cell Biology

Ye Fang, 2011 .

Ligand-Directed Functional Selectivity at the Mu Opioid Receptor Revealed by Label-Free Integrative Pharmacology On-Target

R. Levenson, Ye Fang, Megan M. Morse, 2011, PloS one.

Probing biochemical mechanisms of action of muscarinic M3 receptor antagonists with label-free whole cell assays.

Ye Fang, Huayun Deng, Chaoming Wang, 2012, Analytical chemistry.

Multiple tyrosine metabolites are GPR35 agonists

Ye Fang, Huayun Deng, Haibei Hu, 2012, Scientific Reports.

Dynamic Mass Redistribution Assay Decodes Differentiation of a Neural Progenitor Stem Cell

Ye Fang, A. Ferrie, Haibei Hu, 2012, Journal of biomolecular screening.

Discovery of nitrophenols as GPR35 agonists

Ye Fang, Huayun Deng, 2012 .

Label-free integrative pharmacology on-target of opioid ligands at the opioid receptor family

R. Levenson, Ye Fang, Megan M. Morse, 2013, BMC Pharmacology and Toxicology.

Troubleshooting and deconvoluting label-free cell phenotypic assays in drug discovery.

Ye Fang, 2013, Journal of pharmacological and toxicological methods.

A label-free optical biosensor with microfluidics identifies an intracellular signalling wave mediated through the β(2)-adrenergic receptor.

Ye Fang, A. Ferrie, Huayun Deng, 2013, Integrative biology : quantitative biosciences from nano to macro.

Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors.

Ye Fang, Huayun Deng, Haiyan Sun, 2013, Journal of pharmacological and toxicological methods.

Label-free cell phenotypic profiling decodes the composition and signaling of an endogenous ATP-sensitive potassium channel

J. Lahiri, Ye Fang, Huayun Deng, 2014, Scientific Reports.

Label-free drug discovery

Ye Fang, 2014, Front. Pharmacol..

Label-free cell phenotypic drug discovery.

Ye Fang, 2014, Combinatorial chemistry & high throughput screening.

Divergent Label-free Cell Phenotypic Pharmacology of Ligands at the Overexpressed β2-Adrenergic Receptors

Ye Fang, A. Ferrie, Haiyan Sun, 2014, Scientific Reports.

Label-free single cell kinetics of the invasion of spheroidal colon cancer cells through 3D Matrigel.

Ye Fang, A. Ferrie, Nicole K Febles, 2014, Analytical chemistry.

Label-free cell phenotypic profiling identifies pharmacologically active compounds in two traditional Chinese medicinal plants

Ye Fang, Xinmiao Liang, A. Ferrie, 2014 .

Label-free functional selectivity assays.

Ye Fang, A. Ferrie, Chaoming Wang, 2015, Methods in molecular biology.

Label-Free Cell Phenotypic Profiling and Screening: Techniques, Experimental Design, and Data Assessment

Ye Fang, 2015 .

PTEN deletion potentiates invasion of colorectal cancer spheroidal cells through 3D Matrigel.

Ye Fang, Siddarth Chandrasekaran, Huanyun Deng, 2015, Integrative biology : quantitative biosciences from nano to macro.

Combining label-free cell phenotypic profiling with computational approaches for novel drug discovery

Ye Fang, 2015, Expert opinion on drug discovery.

The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans.

S. Benkovic, Hong Zhao, Ye Fang, 2013, Chemical communications.

Non-Invasive Optical Biosensor for Probing Cell Signaling

Ye Fang, 2007, Sensors.

Ganglioside Microarrays for Toxin Detection

Ye Fang, Joydeep Lahiri, J. Lahiri, 2003 .

Three-Dimensional Cell Cultures in Drug Discovery and Development.

Ye Fang, Ye Fang, R. Eglen, 2017, SLAS discovery : advancing life sciences R & D.

Characteristics of dynamic mass redistribution of epidermal growth factor receptor signaling in living cells measured with label-free optical biosensors.

Ye Fang, Po Ki Yuen, P. Yuen, 2005, Analytical chemistry.

Live cell optical sensing for high throughput applications.

Ye Fang, Ye Fang, 2010, Advances in biochemical engineering/biotechnology.

Label-free optical biosensor for probing integrative role of adenylyl cyclase in G protein-coupled receptor signaling

Ye Fang, Elizabeth Tran, Ye Fang, 2009, Journal of receptor and signal transduction research.

Biosensors: On the Origin of Label-Free Cell Phenotypic Profiles of Drug- Target Interactions

Ye Fang, 2013 .

Label-Free and Non-invasive Biosensor Cellular Assays for Cell Adhesion

Ye Fang, Ye Fang, 2010 .

Probing cytoskeleton modulation by optical biosensors

Ye Fang, Guangshan Li, Ye Fang, 2005, FEBS letters.

Modulating Cell-Cell Communication with a High-Throughput Label-Free Cell Assay

Ye Fang, Guangshan Li, F. Lai, 2012, Journal of laboratory automation.

Interrogation of phosphor-specific interaction on a high-throughput label-free optical biosensor system–Epic® system

M. Eichelberger, A. Frutos, Meng Wu, 2009, Journal of receptor and signal transduction research.

Total Internal Reflection Fluorescence Quantification of Receptor Pharmacology

Ye Fang, 2015, Biosensors.

Resonant Waveguide Grating Imager for Single Cell Monitoring of the Invasion of 3D Speheroid Cancer Cells Through Matrigel.

Ye Fang, Nicole K Febles, Siddarth Chandrasekaran, 2017, Methods in molecular biology.

Label-free tracking of whole-cell response on RGD functionalized surfaces to varied flow velocities generated by fluidic rotation.

C. Hős, B. Szabo, R. Horváth, 2021, Journal of colloid and interface science.

Aspirin metabolites are GPR35 agonists

Ye Fang, Huayun Deng, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

Catalyst-free regioselective hydroxyfluorination and aminofluorination of α,β-unsaturated ketones.

Ye Fang, F. Wang, Jianjun Li, 2019, Organic & biomolecular chemistry.

miR ‐ 30 a ‐ 5 p mitigates autophagy by regulating the Beclin ‐ 1 / ATG 16 pathway in renal ischemia / reperfusion injury

Ye Fang, Lin Zou, He Wei, 2021 .

Anti-Inflammatory Gallic Acid and Wedelolactone Are G Protein-Coupled Receptor-35 Agonists

Ye Fang, Huayun Deng, 2012, Pharmacology.

Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting β-catenin signaling.

Guohui Li, Ye Fang, Xinmiao Liang, 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Resonant waveguide grating biosensor for whole-cell GPCR assays.

Ye Fang, A. Ferrie, Elizabeth Tran, 2009, Methods in molecular biology.

Resonant waveguide grating biosensor for living cell sensing.

Ye Fang, J. Mauro, Ye Fang, 2006, Biophysical journal.

The Three Catecholics Benserazide, Catechol and Pyrogallol are GPR35 Agonists

Ye Fang, Huayun Deng, 2013, Pharmaceuticals.

Thieno[3,2-b]thiophene-2-carboxylic acid derivatives as GPR35 agonists.

Ye Fang, M. He, Huayun Deng, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and Agonistic Activity at the GPR35 of 5,6-Dihydroxyindole-2-carboxylic Acid Analogues.

Ye Fang, Huayun Deng, 2012, ACS medicinal chemistry letters.

Spatial colocalization and functional link of purinosomes with mitochondria

Ye Fang, Chung Yu Chan, Tony Jun Huang, 2016, Science.

Aspirin metabolites are GPR35 agonists

Ye Fang, Huayun Deng, 2012, Naunyn-Schmiedeberg's Archives of Pharmacology.

SAR Studies of N-[2-(1H-Tetrazol-5-yl)phenyl]benzamide Derivatives as Potent G Protein-Coupled Receptor-35 Agonists.

Ye Fang, Xinmiao Liang, Hai-long Piao, 2018, ACS medicinal chemistry letters.

GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis

Ye Fang, Songon An, Stephen J. Benkovic, 2011, Nature chemical biology.

Dynamic mass redistribution assays decode surface influence on signaling of endogenous purinergic P2Y receptors.

Ye Fang, Haiyan Sun, Elizabeth Tran, 2012, Assay and drug development technologies.

G-Protein-Coupled Receptor Microarrays for Multiplexed Compound Screening

J. Lahiri, Ye Fang, Brian L. Webb, 2006, Journal of biomolecular screening.

Liposomal quercetin: evaluating drug delivery in vitro and biodistribution in vivo

Ye Fang, W. Gang, L. Ying, 2012, Expert opinion on drug delivery.

Resonant Waveguide Grating Biosensor for Microarrays

Ye Fang, Ye Fang, 2010 .

Optical Biosensors for Monitoring Dynamic Mass Redistribution in Living Cells Mediated by Epidermal Growth Factor Receptor Activation

Ye Fang, Po Ki Yuen, P. Yuen, 2005, 2005 IEEE Engineering in Medicine and Biology 27th Annual Conference.

Three-Dimensional Cell Cultures in Drug Discovery and Development

Ye Fang, Richard M. Eglen, Ye Fang, 2017, SLAS discovery : advancing life sciences R & D.

Label-free cell phenotypic assessment of the molecular mechanism of action of epidermal growth factor receptor inhibitors

Ye Fang, Chaoming Wang, Ye Fang, 2013 .

Label-free cell-based assays with optical biosensors in drug discovery.

Ye Fang, Ye Fang, 2006, Assay and drug development technologies.

Label-free receptor assays.

Ye Fang, 2010, Drug discovery today. Technologies.

Are label-free investigations the best approach to drug discovery?

Ye Fang, 2015, Future medicinal chemistry.

Resonant waveguide grating imagers for single cell analysis and high throughput screening

Ye Fang, Ye Fang, 2015, SPIE NanoScience + Engineering.

The C-terminal Tail of CRTH2 Is a Key Molecular Determinant That Constrains Gαi and Downstream Signaling Cascade Activation*

L. Pardo, J. M. Mathiesen, E. Kostenis, 2009, Journal of Biological Chemistry.

Chemical genomic analysis of GPR35 signaling.

T. Kenakin, Ye Fang, Xinmiao Liang, 2017, Integrative biology : quantitative biosciences from nano to macro.

G-protein-coupled receptor regulation of de novo purine biosynthesis: a novel druggable mechanism

Ye Fang, S. Benkovic, Hong Zhao, 2013, Biotechnology & genetic engineering reviews.

Air stability of supported lipid membrane spots

Ye Fang, 2011 .

Optical biosensor differentiates signaling of endogenous PAR1 and PAR2 in A431 cells

Ye Fang, Ye Fang, A. Ferrie, 2007, BMC Cell Biology.

Cellular functions of cholesterol probed with optical biosensors.

Ye Fang, Guangshan Li, Ye Fang, 2006, Biochimica et biophysica acta.

Resonant Waveguide Grating Biosensors for Cell Biology and Drug Discovery

Ye Fang, Ye Fang, 2012 .

The Purinosome, a Multi-Protein Complex Involved in the de novo Biosynthesis of Purines in Humans

Ye Fang, Stephen J. Benkovic, S. Benkovic, 2013 .

Label-Free Cell Phenotypic Identification of D-Luciferin as an Agonist for GPR35.

Ye Fang, Huayun Deng, H. Hu, 2016, Methods in molecular biology.

Label-Free Cell Phenotypic Identification of Active Compounds in Traditional Chinese Medicines

Ye Fang, Xinmiao Liang, Xiuli Zhang, 2015 .

Agonist-Directed Desensitization of the β2-Adrenergic Receptor

Ye Fang, Qi Wu, Ann M. Ferrie, 2011, PloS one.

Discovery of 2H-Chromen-2-one Derivatives as G Protein-Coupled Receptor-35 Agonists.

Ye Fang, Xinmiao Liang, Xiuli Zhang, 2017, Journal of medicinal chemistry.

Label-Free Phenotypic Profiling Identified D-Luciferin as a GPR35 Agonist

Ye Fang, Ye Fang, Huayun Deng, 2012, PloS one.

Label-Free Profiling of Ligands for Endogenous Gpcrs Using a Cell-Based High-Throughput Screening Technology

Ye Fang, Guangshan Li, Ann M. Ferrie, 2006 .

Resonant waveguide grating biosensor-enabled label-free and fluorescence detection of cell adhesion.

Ye Fang, Haiyan Sun, Qi Wu, 2013, Sensors and actuators. B, Chemical.

Label-free technologies and pharmacology.

Ye Fang, 2016, Pharmacological Research.

Evaluation of dynamic mass redistribution technology for pharmacological studies of recombinant and endogenously expressed g protein-coupled receptors.

Ye Fang, Alice Gao, Ye Fang, 2008, Assay and drug development technologies.

Discovery of β2- adrenoceptor agonists in Curcuma zedoaria Rosc using label-free cell phenotypic assay combined with two-dimensional liquid chromatography.

Ye Fang, Long Yu, Xinmiao Liang, 2018, Journal of chromatography. A.

G‐Protein‐Coupled Receptor Microarrays

Ye Fang, Anthony G. Frutos, Joydeep Lahiri, 2002, Chembiochem : a European journal of chemical biology.

Editorial: Orphan GPCRs As Emerging Drug Targets

T. Kenakin, Ye Fang, Changlu Liu, 2015, Frontiers in Pharmacology.

GPCR microspot assays on solid substrates.

J. Lahiri, Ye Fang, 2009, Methods in molecular biology.

Membrane protein microarrays.

Ye Fang, Anthony G. Frutos, Joydeep Lahiri, 2002, Journal of the American Chemical Society.

Spreading and segregation of lipids in air-stable lipid microarrays.

Ye Fang, 2006, Journal of the American Chemical Society.

Label-free cell-based assays for GPCR screening.

Ye Fang, Anthony G. Frutos, A. Frutos, 2008, Combinatorial chemistry & high throughput screening.

Functional GPCR microarrays.

E. Mozdy, J. Lahiri, J. Mauro, 2005, Journal of the American Chemical Society.

Solvent-Free Cyanosilylation of Aldehydes and Anti-cervical Cancer Activity of a Highly Porous Zinc-MOF

Ye Fang, Rong Li, Liping Zhang, 2019, Journal of Cluster Science.

Multiplexing G protein-coupled receptors in microarrays: a radioligand-binding assay.

B. Posner, Ye Fang, Brian L. Webb, 2007, Analytical biochemistry.

Label‐free optical biosensor with microfluidics for sensing ligand‐directed functional selectivity on trafficking of thrombin receptor

Ye Fang, Qi Wu, Haiyan Sun, 2011, FEBS letters.

Tyrphostin analogs are GPR35 agonists

Ye Fang, Ye Fang, Huayun Deng, 2011, FEBS letters.

Intensity interrogation near cutoff resonance for label-free cellular profiling

R. Horváth, Y. Nazirizadeh, M. Gerken, 2016, Scientific Reports.