S. Radhakrishnan

发表

Lost in transcription: p21 repression, mechanisms, and consequences.

A. Gartel, S. Radhakrishnan, 2005, Cancer research.

Identification of Estrogen-responsive Genes Using a Genome-wide Analysis of Promoter Elements for Transcription Factor Binding Sites*

Sitharthan Kamalakaran, S. Radhakrishnan, W. T. Beck, 2005, Journal of Biological Chemistry.

Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.

R. Deshaies, S. Radhakrishnan, Candy S. Lee, 2010, Molecular cell.

Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity

Carolyn R. Bertozzi, Tadashi Suzuki, Malte Paulsen, 2017, ACS central science.

Trash Talk: Mammalian Proteasome Regulation at the Transcriptional Level.

S. Radhakrishnan, H. E. Kamber Kaya, Hatem Elif Kamber Kaya, 2020, Trends in genetics : TIG.

Disabling the Protease DDI2 Attenuates the Transcriptional Activity of NRF1 and Potentiates Proteasome Inhibitor Cytotoxicity

S. Radhakrishnan, J. R. Vangala, A. Feygin, 2020, International journal of molecular sciences.

Liver-specific deletion of Ngly1 causes abnormal nuclear morphology and lipid metabolism under food stress.

L. Steinmetz, Petra Jakob, S. Radhakrishnan, 2019, Biochimica et biophysica acta. Molecular basis of disease.

Proteotoxic stress-induced Nrf1 transcriptional program requires a functional TIP60 complex

S. Radhakrishnan, J. R. Vangala, J. Vangala, 2018, bioRxiv.

Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex

S. Radhakrishnan, J. R. Vangala, J. Vangala, 2018, The Journal of Biological Chemistry.

QPI Allows in vitro Drug Screening of Triple Negative Breast Cancer PDX Tumors and Fine Needle Biopsies

D. Guest, S. Radhakrishnan, J. Harrell, 2019, Front. Phys..

FOXM1: The Achilles' heel of cancer?

A. Gartel, S. Radhakrishnan, 2008, Nature Reviews Cancer.

Detection of Salt Tolerant Rice Genotypes at the Seedling Stage Using Molecular Markers: A Genotypic Analysis

S. Radhakrishnan, H. S. Adnan, A. Selvam, 2017 .

Nrf1 can be processed and activated in a proteasome-independent manner

R. Deshaies, E. Krüger, S. Radhakrishnan, 2016, Current Biology.

Proapoptotic compound ARC targets Akt and N-myc in neuroblastoma cells

A. Gartel, P. Houghton, S. Radhakrishnan, 2008, Oncogene.

Time to harness the pro-apoptotic property of NFκB?

S. Radhakrishnan, S. Kamalakaran, 2006, Nature Reviews Cancer.

Pro-apoptotic role of NF-kappaB: implications for cancer therapy.

S. Radhakrishnan, S. Kamalakaran, 2006, Biochimica et biophysica acta.

BET Inhibitors Synergize with Carfilzomib to Induce Cell Death in Cancer Cells via Impairing Nrf1 Transcriptional Activity and Exacerbating the Unfolded Protein Response

S. Radhakrishnan, J. Vangala, Ajay Potluri, 2020, Biomolecules.

Information : Nrf 1 can be processed and activated in a proteasome-independent manner

S. Radhakrishnan, Franziska Sotzny, J. Vangala, 2016 .

A novel transcriptional inhibitor induces apoptosis in tumor cells and exhibits antiangiogenic activity.

A. Gartel, S. Radhakrishnan, 2006, Cancer research.

Pest management services through conservation of biological control agents: review, case studies and field experiences

S. Radhakrishnan, A. Verghese, N. K. Krishna Kumar, 2018, Biocontrol Science and Technology.

A novel anticancer agent ARC antagonizes HIV-1 and HCV

A. Gartel, S. Radhakrishnan, T. Layden, 2007, Oncogene.

RNA interference as a new strategy against viral hepatitis.

A. Gartel, S. Radhakrishnan, T. Layden, 2004, Virology.

Identification of a chemical inhibitor of the oncogenic transcription factor forkhead box M1.

A. Gartel, S. Radhakrishnan, U. Bhat, 2006, Cancer research.

Multiple alternate p21 transcripts are regulated by p53 in human cells

A. Gartel, S. Radhakrishnan, J. Gierut, 2006, Oncogene.

Lost in Transcription : p 21 Repression , Mechanisms , and Consequences

A. Gartel, S. Radhakrishnan, 2005 .

The PPAR-? Agonist Pioglitazone Post-Trancriptionally Induces p21 in PC3 Prostate Cancer but Not in Other Cell Lines

A. Gartel, S. Radhakrishnan, 2005, Cell cycle.

Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle

A. Gartel, E. Kandel, A. Haegebarth, 2004, Oncogene.

p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition

R. Deshaies, S. Radhakrishnan, W. den Besten, 2013, bioRxiv.

Regulation of NRF1, a master transcription factor of proteasome genes: implications for cancer and neurodegeneration

S. Radhakrishnan, Amy Northrop, Holly A. Byers, 2020, Molecular biology of the cell.

A novel p21WAF1/CIP1 transcript is highly dependent on p53 for its basal expression in mouse tissues

A. Gartel, A. Tyner, S. Radhakrishnan, 2004, Oncogene.

Pro-apoptotic role of NF-κB: Implications for cancer therapy

S. Radhakrishnan, S. Kamalakaran, 2006 .

CDK9 Phosphorylates p53 on Serine Residues 33, 315 and 392

A. Gartel, S. Radhakrishnan, 2006, Cell cycle.

P-TEFb inhibitors interfere with activation of p53 by DNA-damaging agents

A. Gartel, S. Radhakrishnan, M. Halasi, 2007, Oncogene.

Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy

S. Radhakrishnan, A. Cuervo, S. Kaushik, 2023, bioRxiv.

Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer

S. Radhakrishnan, A. Feygin, Jacqueline M. Grible, 2023, Scientific reports.

Oncogenic Mutant p53 Sensitizes Non-Small Cell Lung Cancer Cells to Proteasome Inhibition via Oxidative Stress-Dependent Induction of Mitochondrial Apoptosis

S. Radhakrishnan, S. Deb, S. Deb, 2024, bioRxiv.

Targeting of SUMOylation leads to cBAF complex stabilization and disruption of the SS18::SSX transcriptome in Synovial Sarcoma

S. Radhakrishnan, Richard I. J. Kurupi, A. Banito, 2024, bioRxiv.

AI is a viable alternative to high throughput screening: a 318-target study

Eva M García-Cuesta, Frederick S. Vizeacoumar, Stephen J. Capuzzi, 2024, Scientific reports.