T. Jin

发表

The Wnt signaling pathway effector TCF7L2 and type 2 diabetes mellitus.

T. Jin, Ling Liu, 2008, Molecular endocrinology.

Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output

T. Jin, Kun Yang, R. Wei, 2019, EBioMedicine.

Combined Oral Administration of GABA and DPP-4 Inhibitor Prevents Beta Cell Damage and Promotes Beta Cell Regeneration in Mice

T. Jin, Qinghua Wang, G. Prud’homme, 2017, Front. Pharmacol..

Abnormal splicing of SHP-1 protein tyrosine phosphatase in human T cells. Implications for lymphomagenesis.

Yulia Katsman, T. Jin, Xuezhong Ma, 2003, Experimental hematology.

POU Homeodomain Protein Oct-1 Functions as a Sensor for Cyclic AMP*

T. Jin, Ling Liu, Peixiang Wang, 2009, The Journal of Biological Chemistry.

Cell Type-specific Autoregulation of theCaudal-related Homeobox Gene Cdx-2/3 *

T. Jin, Fenghao Xu, F. Xu, 1999, The Journal of Biological Chemistry.

Cyclic AMP signaling stimulates proteasome degradation of thioredoxin interacting protein (TxNIP) in pancreatic beta-cells.

I. G. Fantus, T. Jin, W. Shao, 2010, Cellular signalling.

POU Homeodomain Protein OCT1 Is Implicated in the Expression of the Caudal-related Homeobox Gene Cdx-2*

T. Jin, H. Li, Huiqin Li, 2001, The Journal of Biological Chemistry.

Identification of Domains Mediating Transcriptional Activation and Cytoplasmic Export in the Caudal Homeobox Protein Cdx-3*

D. Drucker, T. Jin, K. Trinh, 1999, The Journal of Biological Chemistry.

Current Understanding on Role of the Wnt Signaling Pathway Effector TCF7L2 in Glucose Homeostasis.

T. Jin, 2016, Endocrine reviews.

CEREBROVASCULAR SAFETY OF SULFONYLUREAS : THE ROLE OF KATP CHANNELS IN NEUROPROTECTION AND STROKE RISK IN SULFONYLUREA TREATMENT OF TYPE 2 DIABETES

R. Liu, T. Jin, Zhong-Ping Feng, 2017 .

Current understanding and controversies on the clinical implications of fibroblast growth factor 21

T. Jin, Yasaman Badakhshi, 2020, Critical reviews in clinical laboratory sciences.

Mechanisms underlying the metabolic beneficial effect of curcumin intervention: Beyond anti-inflammation and anti-oxidative stress

T. Jin, 2019, Obesity Medicine.

Diet Polyphenol Curcumin Stimulates Hepatic Fgf21 Production and Restores Its Sensitivity in High-Fat-Diet–Fed Male Mice

T. Jin, Ling Liu, J. Weng, 2016, Endocrinology.

Both Wnt and mTOR signaling pathways are involved in insulin-stimulated proto-oncogene expression in intestinal cells.

T. Jin, Jane Q. J. Sun, Jane Sun, 2008, Cellular signalling.

The incretin hormone GLP‐1 and mechanisms underlying its secretion

T. Jin, L. Tian, 2016, Journal of diabetes.

Hormones that are involved in metabolic homeostasis: Overview of the past century and future perspectives

T. Jin, J. Feng, 2022, Obesity Medicine.

Dietary Cyanidin-3-Glucoside Attenuates High-Fat-Diet-Induced Body-Weight Gain and Impairment of Glucose Tolerance in Mice via Effects on the Hepatic Hormone FGF21.

T. Jin, W. Ling, Burton B. Yang, 2020, The Journal of nutrition.

Dietary Curcumin Intervention Targets Mouse White Adipose Tissue Inflammation and Brown Adipose Tissue UCP1 Expression

T. Jin, M. Woo, D. Winer, 2018, Obesity.

Hepatic FGF21 is Under the Regulation of the Canonical Wnt Signaling Pathway by Yasaman Badakhshi A thesis submitted in conformity with the requirements

T. Jin, W. Shao, Yasaman Badakhshi, 2020 .

Insulin stimulates the expression of carbohydrate response element binding protein (ChREBP) by attenuating the repressive effect of Pit-1, Oct-1/Oct-2, and Unc-86 homeodomain protein octamer transcription factor-1.

T. Jin, Ling Liu, K. Adeli, 2009, Endocrinology.

Gut Microbiota Metabolism of Anthocyanin Promotes Reverse Cholesterol Transport in Mice Via Repressing miRNA-10b

T. Jin, W. Ling, Dan Li, 2012, Circulation research.

Purified anthocyanin supplementation improves endothelial function via NO-cGMP activation in hypercholesterolemic individuals.

Y. Hao, T. Jin, W. Ling, 2011, Clinical chemistry.

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective

T. Jin, Y. Chiang, Wilfred Ip, 2012, Cell & Bioscience.

GLP-1-derived nonapeptide GLP-1(28-36)amide represses hepatic gluconeogenic gene expression and improves pyruvate tolerance in high-fat diet-fed mice.

T. Jin, W. Shao, Y. Chiang, 2013, American journal of physiology. Endocrinology and metabolism.

Nucleic Acid-Targeting Pathways Promote Inflammation in Obesity-Related Insulin Resistance.

C. Liu, M. Glogauer, E. Engleman, 2016, Cell reports.

Nucleic Acid-Targeting Pa thways Promote Inflammation in Obesity-Related Insulin Resistance Graphical

C. Liu, M. Glogauer, E. Engleman, 2016 .

Role of cyclic AMP signaling in the production and function of the incretin hormone glucagon-like peptide-l Zhiwen Yu ' : "

T. Jin, 2009 .

Hepatic functions of GLP-1 and its based drugs: current disputes and perspectives.

T. Jin, J. Weng, 2016, American journal of physiology. Endocrinology and metabolism.

Hepatic Fibroblast Growth Factor 21 Is Involved in Mediating Functions of Liraglutide in Mice With Dietary Challenge

H. He, T. Jin, W. Ling, 2021, Hepatology.

Brain function of the metabolic hormone fibroblast growth factor 21

T. Jin, Yasaman Badakhshi, 2020 .

Role of the exchange protein directly activated by cyclic adenosine 5'-monophosphate (Epac) pathway in regulating proglucagon gene expression in intestinal endocrine L cells.

T. Jin, Peixiang Wang, M. Rahimi, 2006, Endocrinology.

Ectopic expression of glucagon receptor in skeletal muscles improves glucose homeostasis in a mouse model of diabetes

T. Jin, H. Li, L. Zhu, 2012, Diabetologia.

A site-specific genomic integration strategy for sustained expression of glucagon-like peptide-1 in mouse muscle for controlling energy homeostasis.

T. Jin, W. Jia, Qinghua Wang, 2010, Biochemical and biophysical research communications.

Role of Cdx-2 in insulin and proglucagon gene expression: a study using the RIN-1056A cell line with an inducible gene expression system.

I. G. Fantus, T. Jin, Qinghua Wang, 2005, The Journal of endocrinology.

Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice.

T. Jin, J. Chernoff, W. Shao, 2014, Endocrinology.

-catenin signaling in β cAMP/PKA/n-induced diabetic mice and activates -cell mass and glucose disposal

T. Jin, Qinghua Wang, W. Shao, 2016 .

GLP-1(28-36) improves β-cell mass and glucose disposal in streptozotocin-induced diabetic mice and activates cAMP/PKA/β-catenin signaling in β-cells in vitro.

T. Jin, Qinghua Wang, T. Chai, 2013, American journal of physiology. Endocrinology and metabolism.

Redundant and synergistic effect of Cdx-2 and Brn-4 on regulating proglucagon gene expression.

T. Jin, Peixiang Wang, Xuezhong Ma, 2006, Endocrinology.

The caudal homeobox protein cdx-2/3 activates endogenous proglucagon gene expression in InR1-G9 islet cells.

D. Drucker, T. Jin, F. Wang, 1997, Molecular endocrinology.

The proglucagon gene upstream enhancer contains positive and negative domains important for tissue-specific proglucagon gene transcription.

D. Drucker, T. Jin, 1995, Molecular endocrinology.

Pak1 mediates the stimulatory effect of insulin and curcumin on hepatic ChREBP expression

T. Jin, Ling Liu, J. Chernoff, 2017, Journal of molecular cell biology.

Characterization of a novel silencer element in the human aromatase gene PII promoter

P. Goss, T. Jin, Huiqin Li, 2000, Breast Cancer Research and Treatment.

Oct-1 functions as a sensor for metabolic and stress signals

T. Jin, Peixiang Wang, 2010, Islets.

Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2

T. Jin, Peixiang Wang, 2010, BMC Cell Biology.

Epac is involved in cAMP-stimulated proglucagon expression and hormone production but not hormone secretion in pancreatic alpha- and intestinal L-cell lines.

T. Jin, Peixiang Wang, Qinghua Wang, 2009, American journal of physiology. Endocrinology and metabolism.

Proglucagon gene expression is induced by gastrin-releasing peptide in a mouse enteroendocrine cell line.

D. Drucker, T. Jin, F. Lü, 1996, Endocrinology.

Uniparental Mitochondrial Transmission in the Cultivated Button Mushroom, Agaricus bisporus

T. Jin, P. A. Horgen, 1994, Applied and environmental microbiology.

Investigation of Mitochondrial Transmission in Selected Matings between Homokaryons from Commercial and Wild-Collected Isolates of Agaricus bisporus (= Agaricus brunnescens)

T. Jin, A. Sonnenberg, P. A. Horgen, 1992, Applied and environmental microbiology.

Characterization of SHP-1 protein tyrosine phosphatase transcripts, protein isoforms and phosphatase activity in epithelial cancer cells.

T. Jin, Xuezhong Ma, D. Branch, 2013, Genomics.

The anti-inflammatory feature of glucagon-like peptide-1 and its based diabetes drugs—Therapeutic potential exploration in lung injury

T. Jin, W. Ling, J. Pang, 2021, Acta pharmaceutica Sinica. B.

Betaine supplement alleviates hepatic triglyceride accumulation of apolipoprotein E deficient mice via reducing methylation of peroxisomal proliferator-activated receptor alpha promoter

T. Jin, Li Chen, Yao-zong Tan, 2013, Lipids in Health and Disease.

GABA exerts protective and regenerative effects on islet beta cells and reverses diabetes

Yiming Li, T. Jin, Qinghua Wang, 2011, Proceedings of the National Academy of Sciences.

Extracellular high dosages of adenosine triphosphate induce inflammatory response and insulin resistance in rat adipocytes.

T. Jin, Zhiwen Yu, 2010, Biochemical and biophysical research communications.

Cerebrovascular Safety of Sulfonylureas: The Role of KATP Channels in Neuroprotection and the Risk of Stroke in Patients With Type 2 Diabetes

T. Jin, Zhong-Ping Feng, Hong-Shuo Sun, 2016, Diabetes.

TCF-4 Mediates Cell Type-specific Regulation of Proglucagon Gene Expression by β-Catenin and Glycogen Synthase Kinase-3β*

T. Jin, P. Brubaker, Fenghua Yi, 2005, Journal of Biological Chemistry.

Mechanisms underlying proglucagon gene expression.

T. Jin, 2008, The Journal of endocrinology.

Pbx1 is a co-factor for Cdx-2 in regulating proglucagon gene expression in pancreatic A cells

T. Jin, D. Branch, Tao Liu, 2006, Molecular and Cellular Endocrinology.

The LIM homeodomain protein ISL1 mediates the function of TCF7L2 in pancreatic beta cells.

T. Jin, Zhong-Ping Feng, M. Nostro, 2018, Journal of molecular endocrinology.

The role of insulin signaling in the development of β-cell dysfunction and diabetes

T. Jin, Qinghua Wang, 2009, Islets.

Type I interferon responses drive intrahepatic T cells to promote metabolic syndrome

W. Chapman, M. K. Nøhr, E. Engleman, 2017, Science Immunology.

Epigenetic regulation of TXNIP-mediated oxidative stress and NLRP3 inflammasome activation contributes to SAHH inhibition-aggravated diabetic nephropathy

T. Jin, W. Ling, Honghui Guo, 2021, Redox biology.

Cross talk between the insulin and Wnt signaling pathways: evidence from intestinal endocrine L cells.

I. G. Fantus, T. Jin, P. Brubaker, 2008, Endocrinology.

The involvement of the wnt signaling pathway and TCF7L2 in diabetes mellitus: The current understanding, dispute, and perspective

T. Jin, Y. Chiang, Wilfred Ip, 2012, Cell & Bioscience.

Activation of proglucagon gene transcription through a novel promoter element by the caudal-related homeodomain protein cdx-2/3

D. Drucker, T. Jin, D. Drucker, 1996, Molecular and cellular biology.

The Blimp-1 gene regulatory region directs EGFP expression in multiple hematopoietic lineages and testis in mice

T. Jin, Mingyao Liu, C. Shi, 2008, Transgenic Research.

Insulin alters the expression of components of the Wnt signaling pathway including TCF-4 in the intestinal cells.

T. Jin, Dingyan Wang, Jane Sun, 2010, Biochimica et biophysica acta.

The developmental Wnt signaling pathway effector β-catenin/TCF mediates hepatic functions of the sex hormone estradiol in regulating lipid metabolism

T. Jin, W. Shao, Yasaman Badakhshi, 2019, PLoS biology.

Current understanding and dispute on the function of the Wnt signaling pathway effector TCF7L2 in hepatic gluconeogenesis

T. Jin, 2015, Genes & diseases.

Current Knowledge on the Role of Wnt Signaling Pathway in Glucose Homeostasis

T. Jin, 2016 .

Insulin treatment and high-fat diet feeding reduces the expression of three Tcf genes in rodent pancreas.

T. Jin, Qinghua Wang, D. Irwin, 2010, The Journal of endocrinology.

p21-Activated protein kinases and their emerging roles in glucose homeostasis.

T. Jin, Y. Chiang, 2014, American journal of physiology. Endocrinology and metabolism.

TCF-4 mediates cell type-specific regulation of proglucagon gene expression by beta-catenin and glycogen synthase kinase-3beta.

T. Jin, P. Brubaker, Fenghua Yi, 2005, The Journal of biological chemistry.

Novel GLP-1 Analog Supaglutide Stimulates Insulin Secretion in Mouse and Human Islet Beta-Cells and Improves Glucose Homeostasis in Diabetic Mice

T. Jin, Qinghua Wang, G. Prud’homme, 2019, Front. Physiol..

Insulin detemir enhances proglucagon gene expression in the intestinal L cells via stimulating β-catenin and CREB activities.

T. Jin, Qinghua Wang, Y. Chiang, 2012, American journal of physiology. Endocrinology and metabolism.

MicroRNA-17-5p promotes chemotherapeutic drug resistance and tumour metastasis of colorectal cancer by repressing PTEN expression

T. Jin, Burton B. Yang, Jun Hu, 2014, Oncotarget.

SIRT1 activation attenuates α cell hyperplasia, hyperglucagonaemia and hyperglycaemia in STZ-diabetic mice

T. Jin, K. Thai, Yanling Zhang, 2018, Scientific Reports.

Association between single nucleotide polymorphisms in AKT1 and the risk of prostate cancer in the Chinese Han population.

Z. Huang, Y. Zhu, T. Jin, 2017, Genetics and molecular research : GMR.

Friend or foe? ACE2 inhibitors and GLP-1R agonists in COVID-19 treatment

T. Jin, W. Ling, Mingyao Liu, 2021, Obesity Medicine.

Wnt and beyond Wnt: multiple mechanisms control the transcriptional property of beta-catenin.

Jane Sun, T. Jin, Tianru Jin, 2008, Cellular signalling.

P21-activated protein kinase 1 (Pak1) mediates the cross talk between insulin and β-catenin on proglucagon gene expression and its ablation affects glucose homeostasis in male C57BL/6 mice.

T. Jin, J. Chernoff, X. Xu, 2013, Endocrinology.

P 21-Activated Protein Kinase 1 ( Pak 1 ) Mediates the Cross Talk between Insulin and-Catenin on Proglucagon Gene Expression and Its Ablation Affects Glucose Homeostasis in Male C 57 BL / 6 Mice

T. Jin, J. Chernoff, X. Xu, 2012 .

PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx‐2 by cyclic AMP

T. Jin, Mingyao Liu, Peixiang Wang, 2005, The FEBS journal.

Activation of proglucagon gene transcription by protein kinase-A in a novel mouse enteroendocrine cell line.

D. Drucker, S. Asa, T. Jin, 1994, Molecular endocrinology.

Curcumin Prevents High Fat Diet Induced Insulin Resistance and Obesity via Attenuating Lipogenesis in Liver and Inflammatory Pathway in Adipocytes

I. G. Fantus, T. Jin, T. Chai, 2012, PloS one.

The rho guanosine 5'-triphosphatase, cell division cycle 42, is required for insulin-induced actin remodeling and glucagon-like peptide-1 secretion in the intestinal endocrine L cell.

T. Jin, P. Brubaker, Jane Sun, 2009, Endocrinology.

The expression of dominant negative TCF7L2 in pancreatic beta cells during the embryonic stage causes impaired glucose homeostasis

T. Jin, T. Liang, J. Weng, 2015, Molecular metabolism.

Liver-Specific Expression of Dominant-Negative Transcription Factor 7-Like 2 Causes Progressive Impairment in Glucose Homeostasis

T. Jin, M. Wheeler, W. Shao, 2015, Diabetes.

The Wnt Signaling Pathway Effector TCF7L2 Controls Gut and Brain Proglucagon Gene Expression and Glucose Homeostasis

Lingyun Zhu, T. Jin, D. Belsham, 2013, Diabetes.

The Wnt signaling pathway effector TCF7L2 is upregulated by insulin and represses hepatic gluconeogenesis.

T. Jin, W. Shao, Y. Chiang, 2012, American journal of physiology. Endocrinology and metabolism.

The role of the Wnt signaling pathway in incretin hormone production and function

T. Jin, Y. Chiang, Wilfred Ip, 2012, Front. Physio..

Inhibition of Dexamethasone-induced Fatty Liver Development by Reducing miR-17-5p Levels.

T. Jin, W. Ling, Yaou Zhang, 2015, Molecular therapy : the journal of the American Society of Gene Therapy.

New insight into the mechanisms underlying the function of the incretin hormone glucagon-like peptide-1 in pancreatic β-cells

T. Jin, W. Shao, X. Xiong, 2012, Islets.

Curcumin represses mouse 3T3-L1 cell adipogenic differentiation via inhibiting miR-17-5p and stimulating the Wnt signalling pathway effector Tcf7l2

T. Jin, Burton B. Yang, W. Du, 2017, Cell Death & Disease.

Short-Term Curcumin Gavage Sensitizes Insulin Signaling in Dexamethasone-Treated C57BL/6 Mice.

I. G. Fantus, T. Jin, Burton B. Yang, 2015, The Journal of nutrition.

Nodal induces apoptosis through activation of the ALK7 signaling pathway in pancreatic INS-1 β-cells.

T. Jin, Qinghua Wang, C. Peng, 2012, American journal of physiology. Endocrinology and metabolism.

Protocatechuic acid, a metabolite of anthocyanins, inhibits monocyte adhesion and reduces atherosclerosis in apolipoprotein E-deficient mice.

T. Jin, W. Ling, Xiaoyi Wei, 2010, Journal of agricultural and food chemistry.

A thorough analysis of diabetes research in China from 1995 to 2015: current scenario and future scope

T. Jin, J. Weng, Zekai Wu, 2018, Science China Life Sciences.

Examination of POU homeobox gene expression in human breast cancer cells

P. Goss, T. Jin, D. Branch, 1999, International journal of cancer.

Glucagon-like peptide-1 receptor mediates the beneficial effect of liraglutide in an acute lung injury mouse model involving the thioredoxin-interacting protein

T. Jin, Yu Zhang, Mingyao Liu, 2020, American journal of physiology. Endocrinology and metabolism.

A thorough analysis of diabetes research in China from 1995 to 2015: current scenario and future scope

T. Jin, J. Weng, Zekai Wu, 2018, Science China Life Sciences.

Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells.

J. Palazzo, M. Witek, S. Waldman, 2006, Gastroenterology.

Cyanidin-3-O-β-glucoside upregulates hepatic cholesterol 7α-hydroxylase expression and reduces hypercholesterolemia in mice.

T. Jin, W. Ling, Y. Zhang, 2012, Molecular nutrition & food research.

Hepatic hormone FGF21 and its analogues in clinical trials

T. Jin, W. Shao, Weijuan Shao, 2021, Chronic diseases and translational medicine.

Short‐term semaglutide treatment improves FGF21 responsiveness in primary hepatocytes isolated from high fat diet challenged mice

T. Jin, W. Shao, J. Feng, 2023, Physiological reports.

Liraglutide stimulates the β-catenin signaling cascade in mouse epididymal fat tissue.

T. Jin, Jianqiu Gu, W. Shao, 2022, Journal of molecular endocrinology.

Comparison of Beneficial Metabolic Effects of Liraglutide and Semaglutide in Male C57BL/6J Mice.

T. Jin, Jianqiu Gu, W. Shao, 2021, Canadian journal of diabetes.

Estrogen-Wnt signaling cascade regulates expression of hepatic fibroblast growth Factor 21.

T. Jin, Jim Hu, Jianqiu Gu, 2021, American journal of physiology. Endocrinology and metabolism.

GABA requires GLP-1R to exert its pancreatic function during STZ challenge.

T. Jin, Qinghua Wang, G. Prud’homme, 2020, The Journal of endocrinology.

Combined use of GABA and sitagliptin promotes human β-cell proliferation and reduces apoptosis.

T. Jin, Qinghua Wang, Wenjuan Liu, 2020, The Journal of endocrinology.

New insights into the role of cAMP in the production and function of the incretin hormone glucagon-like peptide-1 (GLP-1).

T. Jin, Zhiwen Yu, Tianru Jin, 2010, Cellular signalling.

Transcriptional Activation of the Proglucagon Gene by Lithium and β-Catenin in Intestinal Endocrine L Cells*

G. Mills, T. Jin, X. Fang, 2003, The Journal of Biological Chemistry.

The POU homeodomain protein OCT3 as a potential transcriptional activator for fibroblast growth factor-4 (FGF-4) in human breast cancer cells.

P. Goss, G. Schultz, T. Jin, 2003, The Biochemical journal.

Curcumin and other dietary polyphenols: potential mechanisms of metabolic actions and therapy for diabetes and obesity.

I. G. Fantus, T. Jin, J. Weng, 2018, American journal of physiology. Endocrinology and metabolism.

Resveratrol intervention attenuates chylomicron secretion via repressing intestinal FXR-induced expression of scavenger receptor SR-B1

T. Jin, W. Ling, C. Mineo, 2023, Nature communications.

Tirzepatide, a new class of incretin-based drug for diabetes

T. Jin, 2023, Obesity Medicine.

Role of cyclic AMP signaling in the production and function of the incretin hormone glucagon-like peptide-1

T. Jin, Zhiwen Yu, 2008 .

Actin filament associated protein mediates c‐Src related SRE/AP‐1 transcriptional activation

T. Jin, Mingyao Liu, M. Lodyga, 2011, FEBS letters.

Letter to the editor: Comment on GLP-1-based drugs and COVID-19 treatment

T. Jin, Mingyao Liu, 2020, Acta Pharmaceutica Sinica B.