Y. Le Marchand-Brustel

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Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2010, Molecular Cancer Therapeutics.

From insulin receptor signalling to Glut 4 translocation abnormalities in obesity and insulin resistance.

Y. Le Marchand-Brustel, J. Tanti, J. Ricort, 1999, Journal of receptor and signal transduction research.

Overexpression of a Constitutively Active Form of Phosphatidylinositol 3-Kinase Is Sufficient to Promote Glut 4 Translocation in Adipocytes*

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1996, The Journal of Biological Chemistry.

Differential effects of insulin and exercise on Rab4 distribution in rat skeletal muscle.

Y. Le Marchand-Brustel, L. Goodyear, M. Hirshman, 1996, Endocrinology.

Different effects of insulin and platelet-derived growth factor on phosphatidylinositol 3-kinase at the subcellular level in 3T3-L1 adipocytes. A possible explanation for their specific effects on glucose transport.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1996, European journal of biochemistry.

Wortmannin inhibits the action of insulin but not that of okadaic acid in skeletal muscle: comparison with fat cells.

E. Van Obberghen, Y. Le Marchand-Brustel, M. Cormont, 1995, Endocrinology.

Effected of insulin and insulin-like growth factor-I on glucose transport and its transporters in soleus muscle of lean and obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, N. Gautier, 1995, Metabolism: clinical and experimental.

Parallel changes in Glut 4 and Rab4 movements in two insulin‐resistant states

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1994, FEBS letters.

Rosiglitazone increases cell surface GLUT4 levels in 3T3-L1 adipocytes through an enhancement of endosomal recycling.

Y. Le Marchand-Brustel, M. Bruce, Laurène Martinez, 2010, Biochemical pharmacology.

Diverse effects of Glut 4 ablation on glucose uptake and glycogen synthesis in red and white skeletal muscle.

Y. Le Marchand-Brustel, R. Burcelin, T. Tsao, 1996, The Journal of clinical investigation.

Fatty acid-induced insulin resistance: role of insulin receptor substrate 1 serine phosphorylation in the retroregulation of insulin signalling.

Y. Le Marchand-Brustel, J. Tanti, Y. Marchand-Brustel, 2003, Biochemical Society transactions.

Dimethyl sulfoxide enhances GLUT4 translocation through a reduction in GLUT4 endocytosis in insulin-stimulated 3T3-L1 adipocytes.

Jinzhong Zhang, Y. Le Marchand-Brustel, A. A. Gurtovenko, 2011, Biochimie.

Subcellular distribution of low molecular weight guanosine triphosphate-binding proteins in adipocytes: colocalization with the glucose transporter Glut 4.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1991, Endocrinology.

Effect of fasting and streptozotocin diabetes on insulin binding and action in the isolated mouse soleus muscle.

Y. Le Marchand-Brustel, Y. Marchand-Brustel, P. Freychet, 1979, The Journal of clinical investigation.

A Crk-II/TC10 Signaling Pathway Is Required For Osmotic Shock-stimulated Glucose Transport*

M. Kanzaki, Y. Le Marchand-Brustel, J. Tanti, 2002, The Journal of Biological Chemistry.

Positive and negative regulation of glucose uptake by hyperosmotic stress.

Y. Le Marchand-Brustel, P. Gual, J. Tanti, 2003, Diabetes & metabolism.

Cannabinoid CB2 Receptor Potentiates Obesity-Associated Inflammation, Insulin Resistance and Hepatic Steatosis

Andreas Zimmer, Sophie Lotersztajn, Alexandre Louvet, 2009, PloS one.

Elevated Expression of Osteopontin May Be Related to Adipose Tissue Macrophage Accumulation and Liver Steatosis in Morbid Obesity

K. Clément, Y. Le Marchand-Brustel, J. Gugenheim, 2009, Diabetes.

Hepatocyte Growth Factor Induces Glucose Uptake in 3T3-L1 Adipocytes through A Gab1/Phosphatidylinositol 3-Kinase/Glut4 Pathway*

Y. Le Marchand-Brustel, J. Tanti, M. Cormont, 2007, Journal of Biological Chemistry.

Hepatic Expression Patterns of Inflammatory and Immune Response Genes Associated with Obesity and NASH in Morbidly Obese Patients

Y. Le Marchand-Brustel, J. Gugenheim, A. Iannelli, 2010, PloS one.

Effects and binding of insulin-like growth factor I in the isolated soleus muscle of lean and obese mice: comparison with insulin.

Y. Le Marchand-Brustel, Y. Marchand-Brustel, E. Froesch, 1979, Endocrinology.

Peroxovanadate induces tyrosine phosphorylation of phosphoinositide-dependent protein kinase-1 potential involvement of src kinase.

A. Casamayor, D. Alessi, Y. Le Marchand-Brustel, 2000, European journal of biochemistry.

A new composite model including metabolic syndrome, alanine aminotransferase and cytokeratin‐18 for the diagnosis of non‐alcoholic steatohepatitis in morbidly obese patients

F. Berthier, Y. Le Marchand-Brustel, J. Gugenheim, 2010, Alimentary pharmacology & therapeutics.

Osmotic regulation of cellular glucose uptake.

Y. Le Marchand-Brustel, J. Tanti, P. Gual, 2007, Methods in enzymology.

Enigma interacts with adaptor protein with PH and SH2 domains to control insulin-induced actin cytoskeleton remodeling and glucose transporter 4 translocation.

Y. Le Marchand-Brustel, J. Tanti, J. Gugenheim, 2006, Molecular endocrinology.

The role of small G-proteins in the regulation of glucose transport (review).

Y. Le Marchand-Brustel, M. Cormont, 2001, Molecular membrane biology.

Potential role of protein kinase B in glucose transporter 4 translocation in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Endocrinology.

Insulin and okadaic acid induce Rab4 redistribution in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The Journal of biological chemistry.

Expression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase B.

Y. Le Marchand-Brustel, M. Cormont, N. Gautier, 2001, The Biochemical journal.

Deciphering the role of GLUT4 N-glycosylation in adipocyte and muscle cell models.

Y. Le Marchand-Brustel, M. Berenguer, R. Govers, 2012, The Biochemical journal.

Rab4b Is a Small GTPase Involved in the Control of the Glucose Transporter GLUT4 Localization in Adipocyte

Y. Le Marchand-Brustel, J. Gugenheim, M. Cormont, 2009, PloS one.

Hypoxia inhibits Cavin-1 and Cavin-2 expression and down-regulates caveolae in adipocytes.

Y. Le Marchand-Brustel, J. Tanti, P. Valet, 2015, Endocrinology.

Alteration in insulin action: role of IRS-1 serine phosphorylation in the retroregulation of insulin signalling.

Y. Le Marchand-Brustel, J. Tanti, Y. Marchand-Brustel, 2004, Annales d'endocrinologie.

Differential effects of okadaic acid on insulin-stimulated glucose and amino acid uptake and phosphatidylinositol 3-kinase activity.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The Journal of biological chemistry.

Defect in skeletal muscle phosphatidylinositol-3-kinase in obese insulin-resistant mice.

Dominique, Stanley, E. Van Obberghen, 1993, The Journal of clinical investigation.

Glucose transporter in insulin sensitive tissues of lean and obese mice. Effect of the thermogenic agent BRL 26830A.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1990, Endocrinology.

Characterization of 6-deoxy-6-iodo-D-glucose: a potential new tool to assess glucose transport.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Nuclear medicine and biology.

Effects of okadaic acid, an inhibitor of protein phosphatases-1 and -2A, on glucose transport and metabolism in skeletal muscle.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1991, The Journal of biological chemistry.

Potential Role of Protein Kinase B in Glucose Transporter 4 Translocation in Adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, Endocrinology.

Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from gold thioglucose obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, N. Gautier, 1995, The American journal of physiology.

Insulin receptor kinase is hyperresponsive in adipocytes of young obese Zucker rats.

E. Van Obberghen, A. Debant, Y. Le Marchand-Brustel, 1987, The American journal of physiology.

Assays of glucose entry, glucose transporter amount, and translocation.

Y. Le Marchand-Brustel, J. Tanti, M. Cormont, 2001, Methods in molecular biology.

Y. Le Marchand-Brustel, A. Bado, M. Buyse, 1999 .

Physiological Role of Cholecystokinin B/Gastrin Receptor in Leptin Secretion1.

Y. Le Marchand-Brustel, A. Bado, M. Buyse, 1999, Endocrinology.

Potential role of 3‐phosphoinositide‐dependent protein kinase 1 (PDK1) in insulin‐stimulated glucose transporter 4 translocation in adipocytes

Y. Le Marchand-Brustel, J. Tanti, S. Grillo, 1999, FEBS letters.

The formation of an intrachain disulfide bond in the leptin protein is necessary for efficient leptin secretion.

Y. Le Marchand-Brustel, T. Issad, V. Zilberfarb, 2004, Biochimie.

Molecular mechanisms of insulin action in normal and insulin-resistant states.

Y. Le Marchand-Brustel, 1999, Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.

Insulin binding and effects in isolated soleus muscle of lean and obese mice.

Y. Le Marchand-Brustel, B. Jeanrenaud, P. Freychet, 1978, The American journal of physiology.

Insulin affects only initiation and not elongation in protein synthesis in soleus muscles of lean and obese mice

Y. Le Marchand-Brustel, S. Monier, Solange Monier, 1982, FEBS letters.

Okadaic acid stimulates IGF-II receptor translocation and inhibits insulin action in adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1993, The American journal of physiology.

Tpl2 Kinase Is Upregulated in Adipose Tissue in Obesity and May Mediate Interleukin-1β and Tumor Necrosis Factor-α Effects on Extracellular Signal–Regulated Kinase Activation and Lipolysis

Y. Le Marchand-Brustel, J. Tanti, M. Laville, 2009, Diabetes.

Aminoisobutyric acid transport in soleus muscles of lean and gold thioglucose-obese mice.

Y. Le Marchand-Brustel, P. Freychet, N. Moutard, 1982, The American journal of physiology.

Regulation of glycogen synthase activity in the isolated mouse soleus muscle. Effect of insulin, epinephrine, glucose and anti-insulin receptor antibodies.

Y. Le Marchand-Brustel, P. Freychet, 1981, Biochimica et biophysica acta.

Studies of insulin insensitivity in soleus muscles of obese mice.

Y. Le Marchand-Brustel, P. Freychet, 1978, Metabolism: clinical and experimental.

Effect of cyclic AMP-dependent protein kinase on insulin receptor tyrosine kinase activity.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1987, The Biochemical journal.

Cross-talk between the Platelet-derived Growth Factor and the Insulin Signaling Pathways in 3T3-L1 Adipocytes*

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1997, The Journal of Biological Chemistry.

Polymyxin B inhibits insulin-induced glucose transporter and IGF II receptor translocation in isolated adipocytes.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1992, European journal of biochemistry.

Alteration of insulin receptor kinase in obese, insulin-resistant mice.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1987, Biochimie.

Lipid-induced insulin resistance in cultured hepatoma cells is associated with a decreased insulin receptor tyrosine kinase activity.

Y. Le Marchand-Brustel, C. Staedel, P. Hubert, 1991, Cell regulation.

Effect of a thermogenic agent, BRL 26830A, on insulin receptors in obese mice.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1988, The American journal of physiology.

Polymyxin B selectively inhibits insulin effects on transport in isolated muscle.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1987, The American journal of physiology.

Insulin Promotes Phosphorylation and Activation of Geranylgeranyltransferase II

Y. Le Marchand-Brustel, M. Cormont, M. Goalstone, 1999, The Journal of Biological Chemistry.

Long-Term Treatment with Lopinavir-Ritonavir Induces a Reduction in Peripheral Adipose Depots in Mice

Y. Le Marchand-Brustel, C. Perrin, M. Aouadi, 2006, Antimicrobial Agents and Chemotherapy.

Long-Term Treatment with Lopinavir-Ritonavir Induces a Reduction in Peripheral Adipose Depots in Mice

Y. Le Marchand-Brustel, C. Perrin, M. Aouadi, 2006, Antimicrobial Agents and Chemotherapy.

Rab4 is phosphorylated by the insulin-activated extracellular-signal-regulated kinase ERK1.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1994, European journal of biochemistry.

The insulin receptor kinase.

S. Gammeltoft, E. Van Obberghen, R. Ballotti, 1985, Biochimie.

Galanin can inhibit insulin release by a mechanism other than membrane hyperpolarization or inhibition of adenylate cyclase.

E. Van Obberghen, Y. Le Marchand-Brustel, M. Cormont, 1989, The Journal of biological chemistry.

Increased adipose tissue expression of hepcidin in severe obesity is independent from diabetes and NASH.

Y. Le Marchand-Brustel, N. Luciani, J. Gugenheim, 2006, Gastroenterology.

Insulin Stimulation of Mitogen-activated Protein Kinase, p90rsk, and p70 S6 Kinase in Skeletal Muscle of Normal and Insulin-resistant Mice

Y. Le Marchand-Brustel, D. Moller, P. Chang, 1995, The Journal of Biological Chemistry.

Insulin receptor: tyrosine kinase activity and insulin action.

S. Gammeltoft, E. Van Obberghen, R. Ballotti, 1989, Reproduction, nutrition, development.

Presence of an insulin-stimulated serine kinase in cell extracts from IM-9 cells.

E. Van Obberghen, R. Ballotti, Y. Le Marchand-Brustel, 1986, Biochemical and biophysical research communications.

Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes.

Y. Le Marchand-Brustel, J. Tanti, M. Laville, 2003, Diabetes.

Role of the FYVE Finger and the RUN Domain for the Subcellular Localization of Rabip4*

Y. Le Marchand-Brustel, M. Cormont, M. Mari, 2001, The Journal of Biological Chemistry.

p38MAP Kinase activity is required for human primary adipocyte differentiation

Y. Le Marchand-Brustel, J. Tanti, F. Bost, 2007, FEBS letters.

Pre- and postweaning studies on development of obesity in mdb/mdb mice.

Y. Le Marchand-Brustel, B. Jeanrenaud, 1978, The American journal of physiology.

Insulin activates glycogen synthase in phosphorylase kinase deficient mice

P. Cohen, Y. Le Marchand-Brustel, P. Cohen, 1979, FEBS letters.

Insulin stimulates tyrosine phosphorylation of its receptor beta-subunit in intact rat hepatocytes.

E. Van Obberghen, M. White, R. Ballotti, 1987, The Biochemical journal.

Positive and negative regulation of insulin signaling through IRS-1 phosphorylation.

Y. Le Marchand-Brustel, J. Tanti, P. Gual, 2005, Biochimie.

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2011, Cancer research.

Retinoic acid activation of the ERK pathway is required for embryonic stem cell commitment into the adipocyte lineage.

C. Dani, Y. Le Marchand-Brustel, F. Bost, 2002, The Biochemical journal.

Hypoxia Decreases Insulin Signaling Pathways in Adipocytes

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2009, Diabetes.

Inhibition of p38MAPK increases adipogenesis from embryonic to adult stages.

Y. Le Marchand-Brustel, F. Bost, M. Aouadi, 2006, Diabetes.

Role of MAPKs in development and differentiation: lessons from knockout mice.

Y. Le Marchand-Brustel, F. Bost, M. Aouadi, 2006, Biochimie.

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells.

C. Bertolotto, I. Ben-Sahra, Y. Le Marchand-Brustel, 2010, Cancer research.

Insulin receptor substrate 1 is phosphorylated by the serine kinase activity of phosphatidylinositol 3-kinase.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1994, The Biochemical journal.

Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice

Y. Le Marchand-Brustel, P. Gual, S. Patouraux, 2013, Science Translational Medicine.

Interleukin-1beta-induced insulin resistance in adipocytes through down-regulation of insulin receptor substrate-1 expression.

Y. Le Marchand-Brustel, J. Tanti, M. Cormont, 2007, Endocrinology.

Serum Markers of Hepatocyte Death and Apoptosis Are Non Invasive Biomarkers of Severe Fibrosis in Patients with Alcoholic Liver Disease

Y. Le Marchand-Brustel, P. Gual, S. Patouraux, 2011, PloS one.

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression.

Shelly C. Lu, K. Clément, R. Andrade, 2012, Journal of proteome research.

Insulin Induces REDD1 Expression through Hypoxia-inducible Factor 1 Activation in Adipocytes*

Y. Le Marchand-Brustel, J. Tanti, F. Bost, 2009, The Journal of Biological Chemistry.

Potential role of Rab4 in the regulation of subcellular localization of Glut4 in adipocytes

E. Van Obberghen, Y. Le Marchand-Brustel, Y. Marchand-Brustel, 1996, Molecular and cellular biology.

CD2AP/CMS Regulates Endosome Morphology and Traffic to the Degradative Pathway Through its Interaction with Rab4 and c‐Cbl

P. Monzo, Y. Le Marchand-Brustel, M. Cormont, 2003, Traffic.

Metformin and cancer therapy

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2012, Current opinion in oncology.

EVIDENCES FOR A BENEFICIAL EFFECT OF METFORMIN IN PREVENTING CANCER IN DIABETIC PATIENTS

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2011 .

The extracellular signal-regulated kinase isoform ERK1 is specifically required for in vitro and in vivo adipogenesis.

C. Dani, J. Pouysségur, Y. Le Marchand-Brustel, 2005, Diabetes.

Serine/threonine phosphorylation of insulin receptor substrate 1 modulates insulin receptor signaling.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1994, The Journal of biological chemistry.

Hyperosmotic Stress Inhibits Insulin Receptor Substrate-1 Function by Distinct Mechanisms in 3T3-L1 Adipocytes*

Y. Le Marchand-Brustel, J. Tanti, P. Gual, 2003, Journal of Biological Chemistry.

The Rab4 effector Rabip4 plays a role in the endocytotic trafficking of Glut 4 in 3T3-L1 adipocytes

P. Monzo, Y. Le Marchand-Brustel, M. Cormont, 2006, Journal of Cell Science.

The interaction between the adaptor protein APS and Enigma is involved in actin organisation.

Y. Le Marchand-Brustel, J. Tanti, R. Barrès, 2005, Experimental cell research.

A FYVE-finger-containing protein, Rabip4, is a Rab4 effector involved in early endosomal traffic.

Y. Le Marchand-Brustel, A. Galmiche, M. Cormont, 2001, Proceedings of the National Academy of Sciences of the United States of America.

Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease.

Shelly C. Lu, K. Clément, Y. Le Marchand-Brustel, 2010, Journal of proteome research.

C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients.

K. Clément, T. Sørensen, E. Zimmermann, 2011, Journal of hepatology.

Clues to CD2-associated protein involvement in cytokinesis.

P. Monzo, Y. Le Marchand-Brustel, A. Loubat, 2005, Molecular biology of the cell.

Insulin-like growth factor-I-stimulated glucose transport in myotubes derived from chicken muscle satellite cells.

Y. Le Marchand-Brustel, J. Tanti, J. Simon, 1993, The Journal of endocrinology.

Expression of a dominant-negative mutant human insulin receptor in the muscle of transgenic mice.

Y. Le Marchand-Brustel, H. Benecke, D. Moller, 1994, The Journal of biological chemistry.

The Osteopontin Level in Liver, Adipose Tissue and Serum Is Correlated with Fibrosis in Patients with Alcoholic Liver Disease

Y. Le Marchand-Brustel, P. Gual, S. Patouraux, 2012, PloS one.

Regulated in Development and DNA Damage Responses -1 (REDD1) Protein Contributes to Insulin Signaling Pathway in Adipocytes

Y. Le Marchand-Brustel, J. Tanti, S. Giorgetti-Peraldi, 2012, PloS one.

The small guanosine triphosphate-binding protein Rab4 is involved in insulin-induced GLUT4 translocation and actin filament rearrangement in 3T3-L1 cells.

P. Vollenweider, Y. Le Marchand-Brustel, J. Olefsky, 1997, Endocrinology.

A Serum Factor Induces Insulin-Independent Translocation of GLUT4 to the Cell Surface which Is Maintained in Insulin Resistance

Y. Le Marchand-Brustel, S. Giorgetti-Peraldi, Laurène Martinez, 2010, PloS one.

Essential role of chicken ovalbumin upstream promoter-transcription factor II in insulin secretion and insulin sensitivity revealed by conditional gene knockout.

M. Vasseur-Cognet, Y. Le Marchand-Brustel, J. Tanti, 2005, Diabetes.

The Rab4A Effector Protein Rabip4 Is Involved in Migration of NIH 3T3 Fibroblasts*

P. Monzo, Y. Le Marchand-Brustel, M. Cormont, 2006, Journal of Biological Chemistry.

Insulin induces a change in Rab5 subcellular localization in adipocytes independently of phosphatidylinositol 3-kinase activation.

E. Van Obberghen, M. Zerial, Y. Le Marchand-Brustel, 1996, Endocrinology.

Rab proteins in endocytosis and Glut4 trafficking

Y. Le Marchand-Brustel, M. Cormont, V. Kaddai, 2007, Acta physiologica.

Insulin-stimulated glucose transport in muscle. Evidence for a protein-kinase-C-dependent component which is unaltered in insulin-resistant mice.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1989, The Biochemical journal.

[Mechanisms of insulin resistance].

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1989, Journees annuelles de diabetologie de l'Hotel-Dieu.

The nitric oxide-donating derivative of acetylsalicylic acid, NCX 4016, stimulates glucose transport and glucose transporters translocation in 3T3-L1 adipocytes.

Y. Le Marchand-Brustel, M. Cormont, V Kaddai, 2008, American journal of physiology. Endocrinology and metabolism.

Potential involvement of the carboxy-terminus of the Glut 1 transporter in glucose transport.

E. Van Obberghen, Y. Le Marchand-Brustel, J. Tanti, 1992, Endocrinology.

Identification of G Protein α-Subunits in RINm5F Cells and Their Selective Interaction with Galanin Receptor

E. Van Obberghen, Y. Le Marchand-Brustel, M. Cormont, 1991, Diabetes.

Functional labeling of insulin receptor subunits in live cells. Alpha 2 beta 2 species is the major autophosphorylated form.

E. Van Obberghen, R. Ballotti, Y. Le Marchand-Brustel, 1989, Journal of Biological Chemistry.

Expression of the glucose transporter GLUT4 in the muscular dystrophic mdx mouse.

E. Van Obberghen, Y. Le Marchand-Brustel, N. Gautier, 1993, Biochemical Journal.

CD2AP, Rabip4, and Rabip4': analysis of interaction with Rab4a and regulation of endosomes morphology.

Y. Le Marchand-Brustel, M. Cormont, M. Mari, 2005, Methods in enzymology.

Metformin, independent of AMPK, induces mTOR inhibition and cell-cycle arrest through REDD1.

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2011, Cancer research.

Physiological role of cholecystokinin B/gastrin receptor in leptin secretion.

Y. Le Marchand-Brustel, A. Bado, M. Buyse, 1999, Endocrinology.

Metformin in Cancer Therapy: A New Perspective for an Old Antidiabetic Drug?

I. Ben-Sahra, Y. Le Marchand-Brustel, J. Tanti, 2010, Molecular Cancer Therapeutics.

Expression of a prenylation-deficient Rab4 inhibits the GLUT4 translocation induced by active phosphatidylinositol 3-kinase and protein kinase B.

Y. Le Marchand-Brustel, M. Cormont, Nadine Gautier, 2001, The Biochemical journal.

Regulated in Development and DNA Damage Responses -1 (REDD1) Protein Contributes to Insulin Signaling Pathway in Adipocytes

Y. Le Marchand-Brustel, J. Tanti, S. Giorgetti-Peraldi, 2012, PloS one.

Brown Adipose Tissue in Lean and Obese Mice: Insulin-Receptor Binding and Tyrosine Kinase Activity

Y. Le Marchand-Brustel, J. Tanti, E. Obberghen, 1986, Diabetes.