C. M. Joyce

发表

Conformational transitions in DNA polymerase I revealed by single-molecule FRET

J. Torella, A. Kapanidis, Y. Santoso, 2009, Proceedings of the National Academy of Sciences.

Conformational changes during normal and error-prone incorporation of nucleotides by a Y-family DNA polymerase detected by 2-aminopurine fluorescence.

C. M. Joyce, N. Grindley, A. Delucia, 2007, Biochemistry.

Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn903.

C. M. Joyce, N. Grindley, 1980, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of the structure and function of the kanamycin-resistance transposon Tn903.

C. M. Joyce, N. Grindley, 1981, Cold Spring Harbor symposia on quantitative biology.

Polymerase structures and function: variations on a theme?

T. Steitz, C. M. Joyce, 1995, Journal of bacteriology.

Can DNA polymerase I (Klenow fragment) serve as a model for other polymerases

C. M. Joyce, 1991 .

Structure-function analysis of 3'-->5'-exonuclease of DNA polymerases.

C. M. Joyce, V. Derbyshire, J. Pinsonneault, 1995, Methods in enzymology.

Genetic mapping and DNA sequence analysis of mutations in the polA gene of Escherichia coli.

C. M. Joyce, N. Grindley, C. Hughes, 1985, Journal of molecular biology.

Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment).

C. M. Joyce, N. Grindley, X. C. Sun, 1992, The Journal of biological chemistry.

A unified polymerase mechanism for nonhomologous DNA and RNA polymerases.

T. Steitz, S. Smerdon, C. M. Joyce, 1994, Science.

Genetic and crystallographic studies of the 3',5'-exonucleolytic site of DNA polymerase I.

T. Steitz, P. Freemont, L. Beese, 1988, Science.

The fidelity of DNA synthesis catalyzed by derivatives of Escherichia coli DNA polymerase I.

T. Kunkel, M. Fitzgerald, K. Bebenek, 1990, The Journal of biological chemistry.

Distinct Roles of the Active-site Mg2+ Ligands, Asp882 and Asp705, of DNA Polymerase I (Klenow Fragment) during the Prechemistry Conformational Transitions*

C. M. Joyce, N. Grindley, Oya Bermek, 2010, The Journal of Biological Chemistry.

Fingers-closing and other rapid conformational changes in DNA polymerase I (Klenow fragment) and their role in nucleotide selectivity.

C. M. Joyce, O. Potapova, N. Grindley, 2008, Biochemistry.

DNA polymerase fidelity: kinetics, structure, and checkpoints

S. Benkovic, C. M. Joyce, 2004 .

Genetic and DNA sequence analysis of the kanamycin resistance transposon Tn 903 ( transposable element / insertion sequence / in vitro mutagenesis / " transposase " )

C. M. Joyce, N. Grindley, 2022 .

Deoxynucleoside Triphosphate and Pyrophosphate Binding Sites in the Catalytically Competent Ternary Complex for the Polymerase Reaction Catalyzed by DNA Polymerase I (Klenow Fragment) (*)

C. M. Joyce, N. Grindley, M. Astatke, 1995, The Journal of Biological Chemistry.

An error-prone family Y DNA polymerase (DinB homolog from Sulfolobus solfataricus) uses a 'steric gate' residue for discrimination against ribonucleotides.

C. M. Joyce, N. Grindley, Angela M DeLucia, 2003, Nucleic acids research.

A single side chain prevents Escherichia coli DNA polymerase I (Klenow fragment) from incorporating ribonucleotides.

C. M. Joyce, N. Grindley, K. Ng, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Choosing the right sugar: how polymerases select a nucleotide substrate.

C. M. Joyce, C M Joyce, Catherine M. Joyce, 1997, Proceedings of the National Academy of Sciences of the United States of America.

DNA polymerase I: from crystal structure to function via genetics

T. Steitz, C. M. Joyce, 1987 .

A domain of the klenow fragment of Escherichia coli DNA polymerase I has polymerase but no exonuclease activity

T. Steitz, D. Ollis, P. Freemont, 1986, Proteins.

Side chains involved in catalysis of the polymerase reaction of DNA polymerase I from Escherichia coli.

S. Benkovic, C. M. Joyce, N. Grindley, 1992, The Journal of biological chemistry.

FUNCTIONAL EVIDENCE THAT THE 3'-5' EXONUCLEASE DOMAIN OF ESCHERICHIA COLI DNA POLYMERASE I EMPLOYS A DIVALENT METAL ION IN LEAVING GROUP STABILIZATION

J. Piccirilli, C. M. Joyce, J. Curley, 1997 .

UmuD2 Inhibits a Non-covalent Step during DinB-mediated Template Slippage on Homopolymeric Nucleotide Runs*

James J Foti, C. M. Joyce, G. Walker, 2010, The Journal of Biological Chemistry.

Construction of a plasmid that overproduces the large proteolytic fragment (Klenow fragment) of DNA polymerase I of Escherichia coli.

C. M. Joyce, N. Grindley, 1983, Proceedings of the National Academy of Sciences of the United States of America.

DNA polymerase catalysis in the absence of Watson-Crick hydrogen bonds: analysis by single-turnover kinetics.

C. M. Joyce, O. Potapova, N. Grindley, 2006, Biochemistry.

Function and structure relationships in DNA polymerases.

T. Steitz, C. M. Joyce, 1994, Annual review of biochemistry.

Use of 2-aminopurine fluorescence to examine conformational changes during nucleotide incorporation by DNA polymerase I (Klenow fragment).

C. M. Joyce, N. Grindley, V. Purohit, 2003, Biochemistry.

Novel blunt-end addition reactions catalyzed by DNA polymerase I of Escherichia coli.

C. M. Joyce, J. Clark, G. P. Beardsley, 1987, Journal of molecular biology.

Method for determining whether a gene of Escherichia coli is essential: application to the polA gene

C. M. Joyce, N. Grindley, 1984, Journal of bacteriology.

Characterization of four new β-tubulin genes and their expression during male flower development in maize (Zea mays L.)

C. M. Joyce, C. Silflow, R. Villemur, 2004, Plant Molecular Biology.

α-Tubulin gene family of maize (Zea mays L.). Evidence for two ancient α-tubulin genes in plants

P. Hussey, C. M. Joyce, C. Silflow, 1992 .

Tubulin gene expression in maize (Zea mays L.). Change in isotype expression along the developmental axis of seedling root.

C. M. Joyce, C. Silflow, R. Villemur, 1992, Journal of molecular biology.

Affinity chromatography of aminoacyl-tRNA synthetases on specific tRNA columns without prior purification of tRNA.

C. M. Joyce, J. Knowles, 1974, Biochemical and biophysical research communications.

The 3′‐5′ exonuclease of DNA polymerase I of Escherichia coli: contribution of each amino acid at the active site to the reaction.

C. M. Joyce, N. Grindley, V. Derbyshire, 1991, The EMBO journal.

Biochemical and mutational studies of the 5'-3' exonuclease of DNA polymerase I of Escherichia coli.

C. M. Joyce, N. Grindley, V. Derbyshire, 1997, Journal of molecular biology.

A Thumb Subdomain Mutant of the Large Fragment of Escherichia coli DNA Polymerase I with Reduced DNA Binding Affinity, Processivity, and Frameshift Fidelity*

T. Kunkel, C. M. Joyce, D. T. Minnick, 1996, The Journal of Biological Chemistry.

Kinetic analysis of the unique error signature of human DNA polymerase ν.

T. Kunkel, C. M. Joyce, O. Potapova, 2011, Biochemistry.

Identification of two genes immediately downstream from the polA gene of Escherichia coli

C. M. Joyce, N. Grindley, 1982, Journal of bacteriology.

Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I.

C. M. Joyce, N. Grindley, W. S. Kelley, 1982, The Journal of biological chemistry.

How DNA travels between the separate polymerase and 3'-5'-exonuclease sites of DNA polymerase I (Klenow fragment).

C. M. Joyce, 1989, The Journal of biological chemistry.

The Mutational Specificity of the Dbh Lesion Bypass Polymerase and Its Implications*

C. M. Joyce, O. Potapova, N. Grindley, 2002, The Journal of Biological Chemistry.

Side Chains That Influence Fidelity at the Polymerase Active Site of Escherichia coli DNA Polymerase I (Klenow Fragment)*

T. Kunkel, K. Bebenek, W. Osheroff, 1999, The Journal of Biological Chemistry.

Identification of residues critical for the polymerase activity of the Klenow fragment of DNA polymerase I from Escherichia coli.

T. Steitz, C. M. Joyce, N. Grindley, 1990, The Journal of biological chemistry.

How E. coli DNA polymerase I (Klenow fragment) distinguishes between deoxy- and dideoxynucleotides.

C. M. Joyce, N. Grindley, M. Astatke, 1998, Journal of molecular biology.

Techniques used to study the DNA polymerase reaction pathway.

C. M. Joyce, 2010, Biochimica et biophysica acta.

No Job Name

S. Benkovic, C. M. Joyce, 2005 .

Comparative Kinetics of Nucleotide Analog Incorporation by Vent DNA Polymerase*

C. M. Joyce, A. F. Gardner, W. Jack, 2004, Journal of Biological Chemistry.

No Job Name

S. Benkovic, C. M. Joyce, 2022 .

Conformational landscapes of DNA polymerase I and mutator derivatives establish fidelity checkpoints for nucleotide insertion

Timothy D. Craggs, A. Kapanidis, Louise Aigrain, 2013, Nature Communications.

Mechanism of DNA replication fidelity for three mutants of DNA polymerase I: Klenow fragment KF(exo+), KF(polA5), and KF(exo-).

S. Benkovic, C. M. Joyce, B. Eger, 1991, Biochemistry.

Interaction of DNA polymerase I (Klenow fragment) with the single-stranded template beyond the site of synthesis.

C. M. Joyce, N. Grindley, R. M. Turner, 2003, Biochemistry.

Determinants of DNA mismatch recognition within the polymerase domain of the Klenow fragment.

C. M. Joyce, E. Thompson, D. Millar, 2002, Biochemistry.

Effects of mutations on the partitioning of DNA substrates between the polymerase and 3'-5' exonuclease sites of DNA polymerase I (Klenow fragment).

C. M. Joyce, D. Millar, W. Lam, 1998, Biochemistry.

Purification of Escherichia coli DNA polymerase I and Klenow fragment.

C. M. Joyce, V. Derbyshire, 1995, Methods in enzymology.

T4 replication: what does "processivity" really mean?

C. M. Joyce, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Prechemistry Nucleotide Selection Checkpoints in the Reaction Pathway of DNA Polymerase I and Roles of Glu710 and Tyr766

C. M. Joyce, N. Grindley, Oya Bermek, 2013, Biochemistry.

The Properties of Steric Gate Mutants Reveal Different Constraints within the Active Sites of Y-family and A-family DNA Polymerases*

C. M. Joyce, O. Potapova, N. Grindley, 2006, Journal of Biological Chemistry.

Discrimination against purine–pyrimidine mispairs in the polymerase active site of DNA polymerase I: A structural explanation

T. Kunkel, C. M. Joyce, N. Grindley, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Coordination between the Polymerase and 5′-Nuclease Components of DNA Polymerase I of Escherichia coli *

C. M. Joyce, N. Grindley, Yang Xu, 2000, The Journal of Biological Chemistry.

DNA Polymerase I, Bacterial

C. M. Joyce, 2013 .

Base Miscoding and Strand Misalignment Errors by Mutator Klenow Polymerases with Amino Acid Substitutions at Tyrosine 766 in the O Helix of the Fingers Subdomain*

T. Kunkel, K. Eckert, C. M. Joyce, 1997, The Journal of Biological Chemistry.

Use of fluorescence resonance energy transfer to investigate the conformation of DNA substrates bound to the Klenow fragment.

S. Balasubramanian, W. S. Furey, M. Osborne, 1998, Biochemistry.

Escherichia coli is essential: application to the Method for determining whether a gene of

C. M. Joyce, N. Grindley, 2013 .

Contacts between the 5′ Nuclease of DNA Polymerase I and Its DNA Substrate*

A. Leschziner, C. M. Joyce, O. Potapova, 2001, The Journal of Biological Chemistry.

Functional implications of the Klenow fragment structure.

T. Steitz, D. Ollis, P. Freemont, 1986, Biochemical Society transactions.

3'-5' exonuclease of Klenow fragment: role of amino acid residues within the single-stranded DNA binding region in exonucleolysis and duplex DNA melting.

C. M. Joyce, O. Potapova, E. Thompson, 2002, Biochemistry.

Nucleotide sequence of the Escherichia coli polA gene and primary structure of DNA polymerase I.

C. M. Joyce, N. Grindley, W. S. Kelley, 1982, The Journal of biological chemistry.

Genetic characterization of early amber mutations in the Escherichia coli polA gene and purification of the amber peptides.

C. M. Joyce, W. S. Kelley, C. Joyce, 1983, Journal of molecular biology.

MethodforDetermining Whether a GeneofEscherichia coli Is Essential: Application tothepolAGene

C. M. Joyce, N. Grindley, 1984 .

THE PRIMARY STRUCTURE OF DNA POLYMERASE I OF E. COLI

C. M. Joyce, N. Grindley, W. S. Kelley, 1980 .

DNA polymerase fidelity: kinetics, structure, and checkpoints.

C. M. Joyce, S. J. Benkovic, 2004, Biochemistry.

Distinct Roles of the Active-site Mg2+ Ligands, Asp882 and Asp705, of DNA Polymerase I (Klenow Fragment) during the Prechemistry Conformational Transitions*

C. M. Joyce, N. Grindley, Oya Bermek, 2010, The Journal of Biological Chemistry.