S. Powell

发表

Pan-cancer analysis of bi-allelic alterations in homologous recombination DNA repair genes

J. Reis-Filho, N. Weinhold, L. Norton, 2017, Nature Communications.

Targeting the DNA damage response for cancer therapy.

S. Powell, R. Bindra, Simon N Powell, 2009, DNA repair.

The Ability of p53 to Activate Downstream Genes p21 WAF1/cip1 and MDM2, and Cell Cycle Arrest following DNA Damage Is Delayed and Attenuated in scid Cells Deficient in the DNA-dependent Protein Kinase*

S. Powell, B. Wu, L. Kachnic, 1999, The Journal of Biological Chemistry.

Differential sensitivity of p53(-) and p53(+) cells to caffeine-induced radiosensitization and override of G2 delay.

S. Friend, M. Eogan, S. Powell, 1995, Cancer research.

Homologous recombination in extrachromosomal plasmid substrates is not suppressed by p53.

S. Powell, J. Dahm-Daphi, H. Willers, 2001, Carcinogenesis.

Cell cycle checkpoint defects contribute to genomic instability in PTEN deficient cells independent of DNA DSB repair

T. Pandita, K. Khanna, R. Parsons, 2009, Cell cycle.

Disassembly of MDC1 Foci Is Controlled by Ubiquitin-Proteasome-dependent Degradation*

Zhefu Ma, S. Powell, S. Scott, 2008, Journal of Biological Chemistry.

Dissociation of p53-mediated suppression of homologous recombination from G1/S cell cycle checkpoint control

S. Powell, H. Wunsch, H. Willers, 2000, Oncogene.

p53 directly enhances rejoining of DNA double-strand breaks with cohesive ends in gamma-irradiated mouse fibroblasts.

S. Powell, W. Tang, H. Willers, 1999, Cancer research.

Clinical Assessment of 2D/3D Registration Accuracy in 4 Major Anatomic Sites Using On-Board 2D Kilovoltage Images for 6D Patient Setup

W. Birkfellner, J. Mechalakos, Guang Li, 2015, Technology in cancer research & treatment.

BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-strand breaks during DNA replication.

S. Powell, R. Fridlich, D. Annamalai, 2015, DNA repair.

Computational methods using genome-wide association studies to predict radiotherapy complications and to identify correlative molecular processes

Joseph O. Deasy, Jung Hun Oh, Barry Rosenstein, 2017, Scientific Reports.

The BRCA1-BRCA2 Pathway of Homologous Recombination and the Opportunity for Synthetic Lethal Approaches to Cancer Therapy

Ciara M. O'Driscoll, E. Balciunaite, S. Powell, 2013 .

Black race as a prognostic factor in triple-negative breast cancer patients treated with breast-conserving therapy: a large, single-institution retrospective analysis

G. Gupta, M. Robson, M. Morrow, 2013, Breast Cancer Research and Treatment.

Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation

S. Powell, L. Kachnic, 2003, Oncogene.

Low local recurrence rate without postmastectomy radiation in node-negative breast cancer patients with tumors 5 cm and larger.

A. Niemierko, T. Buchholz, A. Taghian, 2006, International journal of radiation oncology, biology, physics.

MDC1 interacts with Rad51 and facilitates homologous recombination

Zhefu Ma, S. Powell, Junran Zhang, 2005, Nature Structural &Molecular Biology.

Molecular Pathways: Understanding the Role of Rad52 in Homologous Recombination for Therapeutic Advancement

S. Powell, B. Lok, 2012, Clinical Cancer Research.

Nonhomologous end-joining of ionizing radiation-induced DNA double-stranded breaks in human tumor cells deficient in BRCA1 or BRCA2.

S. Powell, S. DiBiase, Huichen Wang, 2001, Cancer research.

Chest wall radiotherapy: middle ground for treatment of patients with one to three positive lymph nodes after mastectomy.

Barbara L. Smith, A. Niemierko, A. Taghian, 2009, International journal of radiation oncology, biology, physics.

Results of a survey regarding irradiation of internal mammary chain in patients with breast cancer: practice is culture driven rather than evidence based.

R. Jagsi, A. Taghian, A. Makris, 2004, International journal of radiation oncology, biology, physics.

Valproic acid causes radiosensitivity of breast cancer cells via disrupting the DNA repair pathway.

Xiaowei Wang, S. Powell, Zhihui Feng, 2016, Toxicology research.

A DNA repair defect in a radiation-sensitive clone of a human bladder carcinoma cell line.

S. Powell, T. McMillan, S. Edwards, 1992, British Journal of Cancer.

The repair fidelity of restriction enzyme-induced double strand breaks in plasmid DNA correlates with radioresistance in human tumor cell lines.

S. Powell, T. McMillan, 1994, International journal of radiation oncology, biology, physics.

Patterns of Recurrence Among Higher-Risk Patients Receiving Daily External Beam Accelerated Partial-Breast Irradiation to 40 Gy in 10 Fractions

B. Mueller, L. Braunstein, S. Powell, 2019, Advances in radiation oncology.

Interim Results of a Phase I/II Trial of 3D-conformal External Beam Accelerated Partial Breast Irradiation in Patients with Early Breast Cancer

Barbara L. Smith, M. Specht, A. Recht, 2008 .

Bi‐allelic alterations in DNA repair genes underpin homologous recombination DNA repair defects in breast cancer

J. Reis-Filho, William Lee, B. Weigelt, 2017, The Journal of pathology.

A Marker of Homologous Recombination Predicts Pathologic Complete Response to Neoadjuvant Chemotherapy in Primary Breast Cancer

S. Powell, R. Mutter, 2011 .

Radiation field design and regional control in sentinel lymph node‐positive breast cancer patients with omission of axillary dissection

Clifford Hudis, H. Cody, M. Morrow, 2012, Cancer.

Patterns of utilization of adjuvant radiotherapy and outcomes in black women after breast conservation at a large multidisciplinary cancer center.

L. Jacks, S. Powell, Zhigang Zhang, 2011, International journal of radiation oncology, biology, physics.

Mammalian Rad9 Plays a Role in Telomere Stability, S- and G2-Phase-Specific Cell Survival, and Homologous Recombinational Repair

T. Pandita, S. Powell, S. Davey, 2006, Molecular and Cellular Biology.

Chk 2 Phosphorylation of BRCA 1 Regulates DNA Double-Strand Break Repair

S. Powell, J. C. Ghosh, D. Weaver, 2003 .

Perineural invasion as a risk factor for locoregional recurrence of invasive breast cancer

B. Mueller, L. Braunstein, S. Powell, 2021, Scientific Reports.

p53-null cells are more sensitive to ultraviolet light only in the presence of caffeine.

S. Powell, J. DeFrank, W. Tang, 1996, Cancer research.

Can ICAM modulation prevent lung injury from ionizing radiation?

S. Powell, L. Kachnic, 2002, Journal of the National Cancer Institute.

Enhancing radiotherapy through a greater understanding of homologous recombination.

C. Barker, S. Powell, 2010, Seminars in radiation oncology.

Enhancing radiotherapy through a greater understanding of homologous recombination.

C. Barker, S. Powell, 2010, Seminars in radiation oncology.

Novel patterns of complex structural variation revealed across thousands of cancer genome graphs

Lucian P. Smith, Julie M. Behr, M. Zody, 2019, bioRxiv.

Molecular assays of radiation-induced DNA damage.

S. Powell, T. McMillan, S. Whitaker, 1991, European Journal of Cancer.

Regional Lymph Node Involvement Among Patients With De Novo Metastatic Breast Cancer

G. Plitas, E. Morris, B. Mueller, 2020, JAMA network open.

Characteristics and Outcomes of Sentinel Node–Positive Breast Cancer Patients after Total Mastectomy without Axillary-Specific Treatment

H. Cody, M. Morrow, S. Powell, 2012, Annals of Surgical Oncology.

Fractionation for whole breast irradiation: an American Society for Radiation Oncology (ASTRO) evidence-based guideline.

Benjamin D. Smith, F. Vicini, A. Recht, 2011, International journal of radiation oncology, biology, physics.

Workshop on partial breast irradiation: state of the art and the science, Bethesda, MD, December 8-10, 2002.

H. Bartelink, C. Coleman, A. Giuliano, 2004, Journal of the National Cancer Institute.

Radiotherapy for Breast Cancer in the 21st Century

S. Powell, 2010, The breast journal.

The Radiobiology of Accelerated Partial Breast Irradiation

S. Powell, 2006 .

COMMENTARY Workshop on Partial Breast Irradiation: State of the Art and the Science, Bethesda, MD,

H. Bartelink, C. Coleman, A. Giuliano, 2004 .

BRCA1- and BRCA2-Deficient Cells Are Sensitive to Etoposide-Induced DNA Double-Strand Breaks via Topoisomerase II

S. Powell, L. Kachnic, Zhihui Feng, 2007 .

Harnessing the DNA Repair Pathway in Breast Cancer: Germline Mutations/Polymorphisms in Breast Radiation.

S. Powell, Michael D. Green, C. Bergom, 2022, Seminars in radiation oncology.

A P53-Independent DNA Damage Response Suppresses Oncogenic Proliferation and Genome Instability.

Lisle E. Mose, J. Parker, J. Reis-Filho, 2020, Cell reports.

In reply to Hannoun-Levi et al.

A. Taghian, S. Powell, J. Hattangadi, 2012, International journal of radiation oncology, biology, physics.

Phase III Multi-Center, Prospective, Randomized Trial Comparing Single Dose 24 Gy Radiotherapy to a 3-Fraction SBRT Regimen in the Treatment of Oligometastatic Cancer.

Y. Yamada, M. Zelefsky, M. Bilsky, 2021, International journal of radiation oncology, biology, physics.

Model‐based predictions of BRCA1/2 mutation status in breast carcinoma patients treated at an academic medical center

Barbara L. Smith, Barbara L. Smith, D. Finkelstein, 2002, Cancer.

Repair of radiation damage to DNA

S. Powell, J. Dahm-Daphi, H. Willers, 2004, British Journal of Cancer.

Pazopanib radio-sensitization of human sarcoma tumors

G. Schwartz, S. Powell, E. de Stanchina, 2018, Oncotarget.

Reduction in low-dose to normal tissue with the addition of deep inspiration breath hold (DIBH) to volumetric modulated arc therapy (VMAT) in breast cancer patients with implant reconstruction receiving regional nodal irradiation

S. Powell, V. Dumane, Ying Zhou, 2018, Radiation Oncology.

Long-Term Pulmonary Outcomes of a Feasibility Study of Inverse-Planned, Multibeam Intensity Modulated Radiation Therapy in Node-Positive Breast Cancer Patients Receiving Regional Nodal Irradiation.

G. Gupta, Guang Li, B. Mueller, 2019, International journal of radiation oncology, biology, physics.

Early toxicity in patients treated with postoperative proton therapy for locally advanced breast cancer.

A. Goenka, S. Powell, O. Cahlon, 2015, International journal of radiation oncology, biology, physics.

Sorting out the Survival Impact of Radiation Therapy in Early-Stage Invasive Breast Cancer

H. Kuerer, S. Powell, B. Haffty, 2014, Annals of Surgical Oncology.

Quantifying the impact of immediate reconstruction in postmastectomy radiation: a large, dose-volume histogram-based analysis.

P. Cordeiro, W. Shi, A. Ballangrud, 2012, International journal of radiation oncology, biology, physics.

Video surface image guidance for external beam partial breast irradiation.

S. Wahab, E. Klein, S. Powell, 2012, Practical radiation oncology.

Locally advanced breast cancer.

Guang Li, A. Ballangrud, S. Powell, 1996 .

Risk of pneumonitis in breast cancer patients treated with radiation therapy and combination chemotherapy with paclitaxel.

A. Niemierko, A. Taghian, S. Powell, 2001, Journal of the National Cancer Institute.

Prospective evaluation of concurrent paclitaxel and radiation therapy after adjuvant doxorubicin and cyclophosphamide chemotherapy for Stage II or III breast cancer.

E. Winer, J. Bellon, R. Gelman, 2006, International journal of radiation oncology, biology, physics.

A 3-Dimensional Mapping Analysis of Regional Nodal Recurrences in Breast Cancer.

J. Tisnado, S. Powell, E. Gillespie, 2019, International journal of radiation oncology, biology, physics.

Radiation treatment, ATM, BRCA1/2, and CHEK2*1100delC pathogenic variants, and risk of contralateral breast cancer.

Jennifer D. Brooks, W. Woodward, E. John, 2020, Journal of the National Cancer Institute.

ATR-p53 Restricts Homologous Recombination in Response to Replicative Stress but Does Not Limit DNA Interstrand Crosslink Repair in Lung Cancer Cells

S. Powell, J. Dahm-Daphi, H. Willers, 2011, PloS one.

Moving beyond PARP Inhibition in ATM-Deficient Prostate Cancer

S. Powell, J. Setton, 2020, Cancer Research.

Tolerability of Breast Radiotherapy Among Carriers of ATM Germline Variants

M. Robson, Z. Stadler, L. Braunstein, 2021, JCO precision oncology.

The Effect of Surgeon Referral and a Radiation Oncologist Productivity-Based Metric on Radiation Therapy Receipt Among Elderly Women With Early Stage Breast Cancer: Analysis From a Tertiary Cancer Network

M. Morrow, L. Braunstein, S. Powell, 2021, Advances in radiation oncology.

BRCA1- and BRCA2-deficient cells are sensitive to etoposide-induced DNA double-strand breaks via topoisomerase II.

S. Powell, L. Kachnic, Zhihui Feng, 2005, Cancer research.

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

C. Sander, A. Olshen, B. Taylor, 2011, Nature Genetics.

BRCA1 loses the ring but lords over resistance.

S. Powell, 2016, The Journal of clinical investigation.

An unexpected product from a 2 – base pair deletion

S. Powell, 2016 .

AN ANTI-TUMOR IMMUNE RESPONSE IS EVOKED BY PARTIAL-VOLUME SINGLE DOSE RADIATION IN TWO MURINE MODELS

J. Humm, J. Deasy, J. Wolchok, 2019 .

Long-term cosmetic outcomes and toxicities of proton beam therapy compared with photon-based 3-dimensional conformal accelerated partial-breast irradiation: a phase 1 trial.

Barbara L. Smith, M. Specht, A. Recht, 2014, International journal of radiation oncology, biology, physics.

Accelerated partial-breast irradiation using proton beams: initial clinical experience.

Barbara L. Smith, M. Specht, A. Recht, 2006, International journal of radiation oncology, biology, physics.

Breast Radiation Therapy Under COVID-19 Pandemic Resource Constraints—Approaches to Defer or Shorten Treatment From a Comprehensive Cancer Center in the United States

B. Mueller, S. Bakhoum, L. Braunstein, 2020, Advances in Radiation Oncology.

Detection of Internal Mammary Adenopathy in Patients With Breast Cancer by PET/CT and MRI.

E. Morris, D. Dershaw, S. Jacobs, 2015, AJR. American journal of roentgenology.

Radiation Therapy With Iridium Interstitial Implant Brachytherapy After Lumpectomy for T1N0 Breast Cancer: Mammographic Findings

Barbara L. Smith, M. Gadd, A. Taghian, 2001 .

3–5 Risk of Breast Cancer Recurrence and Contralateral Breast Cancer in Relation to BRCA1 and BRCA2 Mutation Status Following Breast-Conserving Surgery and Radiotherapy

S. Powell, 2006 .

The role of RPA2 phosphorylation in homologous recombination in response to replication arrest.

S. Gonzalo, S. Powell, Zhihui Feng, 2010, Carcinogenesis.

The interaction of p53 with replication protein A mediates suppression of homologous recombination

S. Powell, M. Blagosklonny, H. Willers, 2004, Oncogene.

Advances in Brief p 53 Directly Enhances Rejoining of DNA Double-Strand Breaks with Cohesive Ends in g-Irradiated Mouse Fibroblasts 1

S. Powell, H. Willers, Wei Tang, 2000 .

A pilot study of 13 N-ammonia cardiac PET imaging to assess subacute cardiotoxicity following adjuvant intensity-modulated radiotherapy for locally advanced breast cancer

S. Nehmeh, Dipti Gupta, A. Ballangrud, 2021 .

DNA damage and repair following treatment with ionizing radiation.

S. Powell, T. McMillan, 1990, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Advances in Brief p 53-null Cells Are More Sensitive to Ultraviolet Light Only in the Presence of Caffeine '

Jeffrey, S. Powell, Wei Tang, 2006 .

Fhit and CHK1 have opposing effects on homologous recombination repair.

K. Huebner, S. Powell, Hua-Rui Lu, 2005, Cancer research.

Randomized Phase II Trial of Proton Craniospinal Irradiation Versus Photon Involved-Field Radiotherapy for Patients With Solid Tumor Leptomeningeal Metastasis

M. Kris, D. Correa, L. Deangelis, 2022, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Synthetic Lethality in Cancer Therapeutics: The Next Generation.

D. Durocher, J. Reis-Filho, M. Koehler, 2021, Cancer discovery.

Lung dose-volume parameters and the risk of pneumonitis for patients treated with accelerated partial-breast irradiation using three-dimensional conformal radiotherapy.

A. Recht, A. Taghian, S. Powell, 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Overall Survival of Breast Cancer Patients With Locoregional Failures Involving Internal Mammary Nodes

L. Braunstein, S. Powell, E. Gillespie, 2019, Advances in radiation oncology.

How do cells repair DNA damage caused by ionizing radiation

S. Powell, L. Kachnic, P. Anné, 1996 .

Emerging Roles of RAD52 in Genome Maintenance

S. Powell, Manisha Jalan, Kyrie S Olsen, 2019, Cancers.

Accelerated partial breast irradiation using proton beams: Initial dosimetric experience.

A. Taghian, Hsiao-Ming Lu, T. Delaney, 2006, International journal of radiation oncology, biology, physics.

Distinct Mechanisms of Nonhomologous End Joining in the Repair of Site-Directed Chromosomal Breaks with Noncomplementary and Complementary Ends

S. Powell, J. Dahm-Daphi, H. Willers, 2006, Radiation research.

Determinants of surgeon referral and radiation therapy receipt following breast conservation among older women with early-stage breast cancer

M. Morrow, L. Braunstein, S. Powell, 2021 .

Long‐term outcomes in breast cancer patients undergoing immediate 2‐stage expander/implant reconstruction and postmastectomy radiation

Jean L Wright, P. Cordeiro, J. Disa, 2012, Cancer.

External beam accelerated partial-breast irradiation using 32 gy in 8 twice-daily fractions: 5-year results of a prospective study.

Barbara L. Smith, M. Specht, A. Recht, 2012, International journal of radiation oncology, biology, physics.

Radiosensitive human tumour cell lines show misrepair of DNA termini.

S. Powell, T. McMillan, J. Mills, 1998, The British journal of radiology.

Breast ACCELERATED PARTIAL-BREAST IRRADIATION USING PROTON BEAMS : INITIAL CLINICAL EXPERIENCE

Barbara L. Smith, M. Specht, A. Recht, 2006 .

Capitalizing on Cancer Replication Stress by Preventing PAR Chain Turnover: A New Type of Synthetic Lethality.

S. Powell, N. McDermott, Erika S. Buechelmaier, 2019, Cancer cell.

A multi‐institutional prediction model to estimate the risk of recurrence and mortality after mastectomy for T1‐2N1 breast cancer

W. Woodward, H. Kuerer, Benjamin D. Smith, 2022, Cancer.

The radiotherapeutic management of breast cancer: treatment practice in the United States

A. Taghian, S. Powell, L. Kachnic, 2001 .

Partial breast irradiation using external beams: a comparison of 3-d conformal, IMRT and proton therapy treatment planning using dose-volume histogram analysis

A. Taghian, D. Gierga, K. Doppke, 2002 .

Accelerated partial breast irradiation with low-dose-rate interstitial implant brachytherapy after wide local excision: 12-year outcomes from a prospective trial.

Phoebe E. Freer, Barbara L. Smith, M. Gadd, 2012, International journal of radiation oncology, biology, physics.

Reproducibility of chestwall and heart position using surface‐guided versus RPM‐guided DIBH radiotherapy for left breast cancer

J. Mechalakos, E. Yorke, Guang Li, 2022, Journal of applied clinical medical physics.

Early outcomes of breast cancer patients treated with post-mastectomy uniform scanning proton therapy.

L. Braunstein, S. Powell, Henry Tsai, 2019, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

2074 Increased risk of radiation pneumonitis in breast cancer patients treated by concomitant taxol and radiation therapy

A. Taghian, S. Powell, I. Kuter, 1999 .

10-Year Breast Cancer Outcomes in Women ≤35 Years of Age.

M. Morrow, P. Razavi, L. Braunstein, 2020, International journal of radiation oncology, biology, physics.

OP-JNCI200033 1275..1278

Jennifer D. Brooks, W. Woodward, E. John, 2020 .

Androgen receptor signaling regulates DNA repair in prostate cancers.

H. Hieronymus, P. Scardino, M. Zelefsky, 2013, Cancer discovery.

Checkpoint kinase 2-mediated phosphorylation of BRCA1 regulates the fidelity of nonhomologous end-joining.

D. Hallahan, Hong Wang, S. Powell, 2006, Cancer research.

Identification of Novel Radiosensitizers in a High-Throughput, Cell-Based Screen for DSB Repair Inhibitors

H. Kluger, S. Powell, R. Bindra, 2014, Molecular Cancer Therapeutics.

Nonhomologous End Joining Homologous Recombination Repair but Independent of ATR Affecting Cell Radiosensitivity Is Dependent on Updated

S. Powell, Huichen Wang, G. Iliakis, 2004 .

Replication Protein A Phosphorylation Facilitates RAD52-Dependent Homologous Recombination in BRCA-Deficient Cells

G. Borgstahl, S. Powell, Rohini Roy, 2021, Molecular and cellular biology.

Lamin A/C Depletion Enhances DNA Damage-Induced Stalled Replication Fork Arrest

Benjamin P. C. Chen, M. Löbrich, T. Pandita, 2013, Molecular and Cellular Biology.

Recombinational DNA Repair in Cancer and Normal Cells: The Challenge of Functional Analysis

S. Powell, H. Willers, F. Xia, 2002, Journal of biomedicine & biotechnology.

Ataxia telangiectasia: an investigation of the repair defect in the cell line AT5BIVA by plasmid reconstitution.

S. Powell, S. Whitaker, J. Peacock, 1993, Mutation research.

Study design in the evaluation of combined radiotherapy plus chemotherapy.

J. Yarnold, P. Hoskin, S. Powell, 1990, European journal of cancer.

DNA repair and synthetic lethality

S. Powell, Fengmei Zhang, Gongshe Guo, 2011, International Journal of Oral Science.

Consolidative Use of Radiotherapy to Block (CURB) Oligoprogression ― Interim Analysis of the First Randomized Study of Stereotactic Body Radiotherapy in Patients With Oligoprogressive Metastatic Cancers of the Lung and Breast

C. Rudin, D. Gomez, S. Powell, 2021, International Journal of Radiation Oncology*Biology*Physics.

Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell

A. Viale, D. Higginson, S. Powell, 2021, Nucleic acids research.

Irradiation in the setting of collagen vascular disease: acute and late complications.

S. Powell, M. Morris, M M Morris, 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

A Randomized Trial of Mometasone Furoate 0.1% to Reduce High-Grade Acute Radiation Dermatitis in Breast Cancer Patients Receiving Postmastectomy Radiation.

M. Lacouture, S. Powell, Zhigang Zhang, 2018, International journal of radiation oncology, biology, physics.

Radiation Biology for Radiation Oncologists

T. Chan, S. Powell, B. Hristov, 2017 .

BACH1 is critical for homologous recombination and appears to be the Fanconi anemia gene product FANCJ.

S. Cantor, S. Powell, P. Andreassen, 2005, Cancer cell.

Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapy

J. Reis-Filho, B. Weigelt, T. Chan, 2020, Nature Cancer.

Rad51 Paralog Complexes BCDX2 and CX3 Act at Different Stages in the BRCA1-BRCA2-Dependent Homologous Recombination Pathway

S. Powell, Jarin Chun, Erika S. Buechelmaier, 2012, Molecular and Cellular Biology.

Human papillomavirus 16 promotes microhomology-mediated end-joining

N. Lee, N. Riaz, P. Blecua, 2019, Proceedings of the National Academy of Sciences.

The therapeutic significance of mutational signatures from DNA repair deficiency in cancer

N. Lee, N. Riaz, S. Powell, 2018, Nature Communications.

PARP Inhibitor Activity Correlates with SLFN11 Expression and Demonstrates Synergy with Temozolomide in Small Cell Lung Cancer

C. Rudin, B. Teicher, N. Rekhtman, 2016, Clinical Cancer Research.

The Role of the BRCA1 Tumor Suppressor in DNA Double-Strand Break Repair

S. Powell, Junran Zhang, 2005, Molecular Cancer Research.

Correction: Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors

S. Powell, A. Haimovitz-Friedman, Z. Fuks, 2016, PloS one.

Targeting Homologous Recombination in Notch-Driven C. elegans Stem Cell and Human Tumors

S. Powell, A. Haimovitz-Friedman, Z. Fuks, 2015, PloS one.

BRCA1 and BRCA2: different roles in a common pathway of genome protection

S. Powell, Rohini Roy, Rohini Roy, 2011, Nature Reviews Cancer.

Chk2 Phosphorylation of BRCA1 Regulates DNA Double-Strand Break Repair

Zhihui Feng, Fen Xia, S. Powell, 2004, Molecular and Cellular Biology.

BRCA1-BARD1 Complexes Are Required for p53Ser-15 Phosphorylation and a G1/S Arrest following Ionizing Radiation-induced DNA Damage*

Kum Kum Khanna, K. Khanna, S. Powell, 2004, Journal of Biological Chemistry.

Homologous recombination deficiency: how genomic signatures are generated.

J. Reis-Filho, S. Powell, J. Setton, 2021, Current opinion in genetics & development.

Inhibition of non-homologous end joining in Fanconi Anemia cells results in rescue of survival after interstrand crosslinks but sensitization to replication associated double-strand breaks.

S. Powell, Laura J. Eccles, Andrew C. Bell, 2018, DNA repair.

DNA double-strand repair by nonhomologous end joining and its clinical relevance

S. Powell, J. Setton, R. Bindra, 2016 .

RAD52 inactivation is synthetically lethal with deficiencies in BRCA1 and PALB2 in addition to BRCA2 through RAD51-mediated homologous recombination

S. Powell, A. Carley, B. Lok, 2013, Oncogene.

Tumour-specific PI3K inhibition via nanoparticle-targeted delivery in head and neck squamous cell carcinoma

J. Humm, J. Baselga, J. Healey, 2017, Nature Communications.

DNA Damage Induces p53-dependent BRCA1 Nuclear Export*

Zhihui Feng, Fen Xia, S. Powell, 2004, Journal of Biological Chemistry.

Development of an assay to measure mutagenic non-homologous end-joining repair activity in mammalian cells

S. Powell, R. Bindra, M. Jasin, 2013, Nucleic acids research.

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

T. Pandita, S. Powell, S. Scott, 2010, Proceedings of the National Academy of Sciences.

Chromosomal instability drives metastasis through a cytosolic DNA response

Samuel F. Bakhoum, Subramanian Venkatesan, Nancy Y. Lee, 2017, Nature.

A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer.

Zhihui Feng, Issam M El Naqa, Xiaowei Wang, 2009, Gynecologic oncology.

Pathogenic ATM Mutations in Cancer and a Genetic Basis for Radiotherapeutic Efficacy.

M. Zelefsky, J. Reis-Filho, B. Weigelt, 2020, Journal of the National Cancer Institute.

The implications of genetic testing on radiotherapy decisions: a guide for radiation oncologists.

W. Woodward, N. Riaz, D. Higginson, 2019, International journal of radiation oncology, biology, physics.

The Landscape of Somatic Genetic Alterations in Breast Cancers from CHEK2 Germline Mutation Carriers

J. Reis-Filho, L. Norton, B. Weigelt, 2019, JNCI cancer spectrum.

The Landscape of Somatic Genetic Alterations in Breast Cancers From ATM Germline Mutation Carriers.

Rui Bi, Ronglai Shen, Nadeem Riaz, 2018, Journal of the National Cancer Institute.

The EMSY threonine 207 phospho-site is required for EMSY-driven suppression of DNA damage repair

D. Levine, P. Jelinic, P. Cybulska, 2017, Oncotarget.

Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination

J. Reis-Filho, K. Offit, B. Weigelt, 2021, npj Breast Cancer.

Germline RAD51B variants confer susceptibility to breast and ovarian cancers deficient in homologous recombination

J. Reis-Filho, K. Offit, B. Weigelt, 2021, NPJ breast cancer.

High Frequency and Error-prone DNA Recombination in Ataxia Telangiectasia Cell Lines (*)

S. Powell, K. Mekeel, J. DeFrank, 1996, The Journal of Biological Chemistry.

A DNA repair defect in a radiation-sensitive clone of a human bladder carcinoma cell line.

S. Powell, T. McMillan, S. Edwards, 1992, British Journal of Cancer.

Clonal variation of DNA repair in a human glioma cell line.

S. Powell, T. McMillan, 1991, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Use of tamoxifen with postsurgical irradiation may improve survival in estrogen and progesterone receptor-positive male breast cancer.

A. E. Hirsch, A. Taghian, S. Powell, 2011, Clinical breast cancer.

Precision Radiotherapy: Reduction in Radiation for Oropharyngeal Cancer in the 30 ROC Trial.

Lydia Y. Liu, Takafumi N. Yamaguchi, J. Humm, 2021, Journal of the National Cancer Institute.

Paclitaxel decreases the interstitial fluid pressure and improves oxygenation in breast cancers in patients treated with neoadjuvant chemotherapy: clinical implications.

Y. Boucher, A. Taghian, S. Powell, 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

BRCA2 keeps Rad51 in line. High-fidelity homologous recombination prevents breast and ovarian cancer?

S. Powell, H. Willers, F. Xia, 2002, Molecular cell.

The biology of radioresistance: similarities, differences and interactions with drug resistance

S. Powell, E. Abraham, 2004, Cytotechnology.

The molecular basis of radiosensitivity and chemosensitivity in the treatment of breast cancer.

S. Powell, F. Xia, 2002, Seminars in radiation oncology.

Impact of an In Situ Component on Outcome After In-Breast Tumor Recurrence in Patients Treated with Breast-Conserving Therapy

H. Cody, L. Braunstein, S. Powell, 2017, Annals of Surgical Oncology.

Examining the prevalence of homologous recombination repair defects in ER+ breast cancers

D. Higginson, S. Powell, Atif J. Khan, 2022, Breast Cancer Research and Treatment.

Exponential Increase in Relative Biological Effectiveness Along Distal Edge of a Proton Bragg Peak as Measured by Deoxyribonucleic Acid Double-Strand Breaks.

M. Lovelock, D. Higginson, S. Powell, 2016, International journal of radiation oncology, biology, physics.

Current Perceptions Regarding Surgical Margin Status After Breast-Conserving Therapy: Results of a Survey

Saveli Goldberg, Reshma Jagsi, Alphonse Taghian, 2005, Annals of surgery.

Radiotherapy for invasive breast cancer in North America and Europe: results of a survey.

R. Jagsi, A. Taghian, S. Powell, 2005, International journal of radiation oncology, biology, physics.

The management of ductal carcinoma in situ in North America and Europe

R. Jagsi, A. Taghian, S. Powell, 2004, Cancer.

The Role of the BRCA 1 Tumor Suppressor in DNA Double-Strand Break Repair

S. Powell, Junran Zhang, 2005 .

Risk of lymphedema after regional nodal irradiation with breast conservation therapy.

A. Taghian, S. Powell, L. Kachnic, 2003, International journal of radiation oncology, biology, physics.

Mitotic DNA Damage Response: At the Crossroads of Structural and Numerical Cancer Chromosome Instabilities.

D. Compton, S. Bakhoum, S. Powell, 2017, Trends in cancer.

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

N. Schultz, M. Berger, C. Iacobuzio-Donahue, 2020, Clinical Cancer Research.

Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability

D. Higginson, S. Powell, Z. Fuks, 2021, Cancer Research.

Lamin A/C Depletion Enhances DNA Damage-Induced Stalled Replication Fork Arrest

Benjamin P. C. Chen, M. Löbrich, T. Pandita, 2013, Molecular and Cellular Biology.

Templated insertions are associated specifically with BRCA2 deficiency and overall survival in advanced ovarian cancer.

N. Weinhold, D. Higginson, S. Powell, 2022, Molecular Cancer Research.

Recombinational Repair Survival , and Homologous-Phase-Specific Cell 2 Stability , Sand G Mammalian Rad 9 Plays a Role in Telomere

T. Pandita, S. Powell, S. Davey, 2006 .

Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations

J. Baselga, G. Gupta, C. Chung, 2015, Clinical Cancer Research.

Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM

T. Chan, N. Lee, I. Ganly, 2016, Oncotarget.

The therapeutic significance of mutational signatures from DNA repair deficiency in cancer

N. Riaz, S. Powell, J. Setton, 2018, Nature Communications.

The Effect of Molecular Subtype and Residual Disease on Locoregional Recurrence in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy and Postmastectomy Radiation

M. Morrow, S. Powell, S. Modi, 2015, Annals of Surgical Oncology.

Tubular Carcinoma of the Breast: a Retrospective Analysis and Review of the Literature

Barbara L. Smith, M. Gadd, A. Taghian, 2005, Breast Cancer Research and Treatment.

Inactivation of p53 results in high rates of homologous recombination

S. Powell, L. Kachnic, K. Mekeel, 1997, Oncogene.

Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies

D. Sgroi, A. Taghian, S. Powell, 2009, Molecular Cancer Research.

Localized therapy for male breast cancer: functional advantages with comparable outcomes using breast conservation.

Shannon Fogh, A. Taghian, S. Powell, 2013, Clinical breast cancer.

Breast-Conserving Therapy Achieves Locoregional Outcomes Comparable to Mastectomy in Women with T1-2N0 Triple-Negative Breast Cancer

M. Robson, M. Morrow, S. Powell, 2013, Annals of Surgical Oncology.

Locoregional recurrence rates and prognostic factors for failure in node-negative patients treated with mastectomy: implications for postmastectomy radiation.

R. Jagsi, A. Taghian, S. Powell, 2003, International journal of radiation oncology, biology, physics.

Postmastectomy Radiation in Breast Cancer Patients With Pathologically Positive Lymph Nodes After Neoadjuvant Chemotherapy: Usage Rates and Survival Trends.

M. Mazumdar, S. Powell, E. Moshier, 2017, International journal of radiation oncology, biology, physics.

Therapeutic exploitation of tumor cell defects in homologous recombination.

S. Powell, L. Kachnic, 2008, Anti-cancer agents in medicinal chemistry.

Helical tomotherapy planning for left-sided breast cancer patients with positive lymph nodes: comparison to conventional multiport breast technique.

D. Low, S. Mutic, S. Goddu, 2009, International journal of radiation oncology, biology, physics.

The Effect of Adjuvant Trastuzumab on Locoregional Recurrence of Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer Treated with Mastectomy

M. Morrow, H. McArthur, N. Riaz, 2015, Annals of Surgical Oncology.

A phase 2 clinical trial assessing the efficacy and safety of pembrolizumab and radiotherapy in patients with metastatic triple‐negative breast cancer

H. McArthur, C. Barker, S. Powell, 2019, Cancer.

Dose-volume analysis of radiotherapy for T1N0 invasive breast cancer treated by local excision and partial breast irradiation by low-dose-rate interstitial implant.

Barbara L. Smith, M. Gadd, A. Taghian, 2002, International journal of radiation oncology, biology, physics.

Tumor bed delineation for external beam accelerated partial breast irradiation: a systematic review.

Guang Li, S. Powell, P. Elkhuizen, 2013, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Favorable prognosis in patients with T1a/T1bN0 triple‐negative breast cancers treated with multimodality therapy

C. Hudis, E. Brogi, G. Gupta, 2012, Cancer.

An Antitumor Immune Response Is Evoked by Partial-Volume Single-Dose Radiation in 2 Murine Models.

J. Humm, J. Deasy, J. Wolchok, 2019, International journal of radiation oncology, biology, physics.

Metastasis and immune evasion from extracellular cGAMP hydrolysis.

O. Elemento, M. Salto‐Tellez, J. Reis-Filho, 2020, Cancer discovery.

Chronic hypoxia decreases synthesis of homologous recombination proteins to offset chemoresistance and radioresistance.

Marianne Koritzinsky, Helen Zhao, R. Bristow, 2008, Cancer research.

Axitinib sensitization of high Single Dose Radiotherapy.

S. Powell, A. Haimovitz-Friedman, Z. Fuks, 2014, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Homologous recombination is the principal pathway for the repair of DNA damage induced by tirapazamine in mammalian cells.

Y. Pommier, W. Wilson, S. Powell, 2008, Cancer research.

Dose-escalated total body irradiation and autologous stem cell transplantation for refractory hematologic malignancy.

S. Powell, T. Spitzer, C. Colby, 2002, International journal of radiation oncology, biology, physics.

Single-dose radiotherapy disables tumor cell homologous recombination via ischemia/reperfusion injury

Evis Sala, Howard J. Halpern, Michael J. Zelefsky, 2019, The Journal of clinical investigation.

The role of radiation therapy for primary breast cancer.

A. Taghian, S. Powell, 1999, The Surgical clinics of North America.

A pilot study of 13N-ammonia cardiac PET imaging to assess subacute cardiotoxicity following adjuvant intensity-modulated radiotherapy for locally advanced breast cancer.

S. Nehmeh, Dipti Gupta, A. Ballangrud, 2020, Clinical imaging.

Negative Regulation of AKT Activation by BRCA1.

T. Ludwig, T. Pandita, S. Powell, 2008, Cancer research.

A new role for a tumor-suppressing protein

S. Powell, J. Setton, 2018, eLife.

Detection of Early Human Papillomavirus-Associated Cancers by Liquid Biopsy.

A. Viale, N. E. Babady, N. Lee, 2019, JCO precision oncology.

Nonhomologous end-joining of site-specific but not of radiation-induced DNA double-strand breaks is reduced in the presence of wild-type p53

S. Powell, J. Dahm-Daphi, H. Willers, 2005, Oncogene.

Breast conservation among older patients with early‐stage breast cancer: Locoregional recurrence following adjuvant radiation or hormonal therapy

M. Morrow, B. Mueller, L. Braunstein, 2021, Cancer.

Novel Inpatient Radiation Oncology Consult Service Model Reduces Hospital Length of Stay.

D. Gomez, S. Powell, O. Cahlon, 2021, JCO oncology practice.

Efficacy of Mometasone Furoate in the Reduction of Moderate/Severe Radiation Dermatitis in Breast Cancer Patients Following Mastectomy

G. Gupta, M. Lacouture, S. Powell, 2016 .

A uniform and versatile surface‐guided radiotherapy procedure and workflow for high‐quality breast deep‐inspiration breath‐hold treatment in a multi‐center institution

E. Yorke, Guang Li, S. Powell, 2022, Journal of applied clinical medical physics.

Valproic acid sensitizes breast cancer cells to hydroxyurea through inhibiting RPA2 hyperphosphorylation-mediated DNA repair pathway.

Xiaowei Wang, S. Powell, Zhihui Feng, 2017, DNA repair.

Bilateral implant reconstruction does not affect the quality of postmastectomy radiation therapy.

P. Cordeiro, J. Disa, W. Shi, 2014, Medical dosimetry : official journal of the American Association of Medical Dosimetrists.

A dosimetry study of post‐mastectomy radiation therapy with AeroForm tissue expander

H. Kuo, Guang Li, L. Kuo, 2020, Journal of applied clinical medical physics.

Radiotherapy and breast reconstruction: complications and cosmesis with TRAM versus tissue expander/implant.

A. Niemierko, A. Taghian, S. Powell, 2002, International journal of radiation oncology, biology, physics.

Salvage of locally recurrent breast cancer with repeat breast conservation using 45 Gy hyperfractionated partial breast re-irradiation

H. Cody, B. Mueller, L. Braunstein, 2021, Breast Cancer Research and Treatment.

S. Powell, V. Dumane, Ying Zhou, 2018, Radiation oncology.

Accuracy of Magnetic Resonance Imaging–Guided Biopsy to Verify Breast Cancer Pathologic Complete Response After Neoadjuvant Chemotherapy

Danny F. Martinez, L. Norton, E. Brogi, 2021, JAMA network open.

Clinical experience with a 3D surface patient setup system for alignment of partial-breast irradiation patients.

Christoph Bert, George T. Y. Chen, A. Taghian, 2006, International journal of radiation oncology, biology, physics.

The Effect of Delaying Radiation Therapy for Systemic Chemotherapy on Local-regional Control in Breast Cancer

A. Taghian, S. Powell, L. Kachnic, 2004, Breast Cancer Research and Treatment.

Pragmatic randomised clinical trial of proton versus photon therapy for patients with non-metastatic breast cancer: the Radiotherapy Comparative Effectiveness (RadComp) Consortium trial protocol

C Daniel Mullins, Mark Pankuch, L Christine Fang, 2019, BMJ Open.

1-1-2008 Biomarkers and mechanisms of FANCD 2 function

S. Powell, L. Kachnic, K. Held, 2013 .

Biomarkers and Mechanisms of FANCD2 Function

S. Powell, L. Kachnic, H. Willers, 2008, Journal of biomedicine & biotechnology.

Education and Training for Radiation Scientists: Radiation Research Program and American Society of Therapeutic Radiology and Oncology Workshop, Bethesda, Maryland, May 12–14, 2003

Rosemary S. L. Wong, C. N. Coleman, G. A. Alexander, 2003, Radiation research.

Most Breast Cancer Patients with T1-2 Tumors and One to Three Positive Lymph Nodes Do Not Need Postmastectomy Radiotherapy

M. Morrow, S. Powell, M. Stempel, 2018, Annals of Surgical Oncology.

Abstract GS4-08: Comprehensive genomic profiling of patients with breast cancer identifies germline-somatic interactions mediating therapy resistance

M. Berger, S. Chandarlapaty, J. Reis-Filho, 2022, Cancer Research.

The effect of tumor size and lymph node status on breast carcinoma lethality

Barbara L. Smith, D. Sgroi, A. Taghian, 2003, Cancer.

The effect of age in the outcome and treatment of older women with ductal carcinoma in situ.

H. Cody, A. Goenka, S. Powell, 2011, Breast.

Late-Breaking Abstracts: ASTRO's 64th Annual Meeting (October 23-26, 2022) Study of vs. Followed by

C. Rudin, N. Lee, N. Riaz, 2022 .

The growth of academic radiation oncology: a survey of endowed professorships in radiation oncology.

S. Powell, T. Wasserman, Steven M. Smith, 2009, International journal of radiation oncology, biology, physics.

The nuclear deubiquitinase BAP 1 is commonly inactivated by somatic mutations and 3 p 21 . 1 losses in malignant pleural mesothelioma

C. Sander, A. Olshen, B. Taylor, 2015 .

Final Analysis of Consolidative Use of Radiotherapy to Block (CURB) Oligoprogression Trial - A Randomized Study of Stereotactic Body Radiotherapy for Oligoprogressive Metastatic Lung and Breast Cancers

C. Rudin, J. Reis-Filho, N. Lee, 2022, International Journal of Radiation Oncology*Biology*Physics.

Initial dosimetric experience using simple three-dimensional conformal external-beam accelerated partial-breast irradiation.

Barbara L. Smith, M. Specht, A. Recht, 2006, International journal of radiation oncology, biology, physics.

Locoregional Control Benefit of a Tumor Bed Boost for Ductal Carcinoma In Situ

B. Mueller, L. Braunstein, S. Powell, 2023, Advances in radiation oncology.

Pathogenic Mutations in ATM Predict for Enhanced Local Control in Prostate Cancers Treated with Radiation Thearpy

M. Zelefsky, J. Reis-Filho, T. Chan, 2018, International Journal of Radiation Oncology*Biology*Physics.

Proton Reirradiation for Recurrent or New Primary Breast Cancer in the Setting of Prior Breast Irradiation.

L. Braunstein, S. Powell, D. Mah, 2021, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

BRCA1 and BRCA2: important differences with common interests

S. Powell, Rohini Roy, Jarin Chun, 2012, Nature Reviews Cancer.

IMRT for breast cancer--balancing outcomes, patient selection, and resource utilization.

S. Powell, L. Kachnic, 2011, Journal of the National Cancer Institute.

1–41 Fractionation Sensitivity and Dose Response of Late Adverse Effects in the Breast After Radiotherapy for Early Breast Cancer: Long-Term Results of a Randomised Trial

S. Powell, 2006 .

Accelerated Partial Breast Irradiation: Association of Dosimetric Parameters With Patient-Reported Outcomes

L. Braunstein, S. Powell, K. Lapen, 2023, Advances in radiation oncology.

Phase II Randomized Trial Comparing Proton Craniospinal Irradiation with Photon Involved-Field Radiotherapy for Patients with Solid Tumor Leptomeningeal Metastasis

L. Deangelis, N. Lee, R. Young, 2022, International Journal of Radiation Oncology*Biology*Physics.

Feasibility of breast-conservation therapy and hypofractionated radiation in the setting of prior breast augmentation.

M. Morrow, E. Zabor, L. Braunstein, 2020, Practical radiation oncology.

Radiation Resistance in Cancer Therapy: Meeting Summary and Research Opportunities Report of an NCI Workshop held September 1–3, 2010

P. Glazer, J. Grandis, Q. Le, 2011, Radiation research.

Radiation Resistance in Cancer Therapy: Meeting

P. Glazer, J. Grandis, Q. Le, 2011 .

Inhibition of Phosphatidylinositol-5-Phosphate 4-Kinases (PI5P4Kα and β) Inhibits Proliferation and Radiosensitizes Triple Negative Breast Cancer Cells Harboring p53 Mutations

N. Gray, Tinghu Zhang, L. Cantley, 2015 .

p53 suppresses hyper-recombination by modulating BRCA1 function.

Zhihui Feng, Yue Luo, S. Powell, 2015, DNA repair.

Set-up uncertainty in accelerated partial-breast irradiation using 3D- conformal external beam radiotherapy: A companion study to a prospective phase I ongoing trial

A. Taghian, K. Doppke, S. Powell, 2004 .

Prophylactic Radiation Therapy vs. Standard-of-Care for Patients with High-Risk, Asymptomatic Bone Metastases: A Multicenter, Randomized Phase II Trial

C. Barker, Y. Yamada, R. Kotecha, 2022, International Journal of Radiation Oncology*Biology*Physics.

Dynamic Mutational Landscape of CSF Circulating Tumor DNA and Predictors of Survival after Proton Craniospinal Irradiation for Leptomeningeal Metastases.

M. Berger, N. Weinhold, D. Higginson, 2022, Clinical cancer research : an official journal of the American Association for Cancer Research.

Metaplastic carcinoma of the breast: matched cohort analysis of recurrence and survival

M. Bernstein, B. Mueller, L. Braunstein, 2023, Breast Cancer Research and Treatment.

Homologous recombination research is heating up and ready for therapy

S. Powell, L. Kachnic, 2011, Proceedings of the National Academy of Sciences.

Long-molecule scars of backup DNA repair in BRCA1- and BRCA2-deficient cancers

Julie M. Behr, O. Elemento, J. Reis-Filho, 2023, Nature.

Non-cell-autonomous cancer progression from chromosomal instability

Ashley M. Laughney, J. Reis-Filho, M. Hubisz, 2023, Nature.

Genomic analysis and clinical correlations of non-small cell lung cancer brain metastasis

N. Schultz, J. Reis-Filho, B. Mueller, 2023, Nature communications.

Accelerated partial-breast irradiation using 3D Conformal External Beam Radiotherapy for patients with early-stage breast cancer: Preliminary results of an ongoing Phase I trial

Barbara L. Smith, A. Recht, M. Gadd, 2004 .

Radiation-induced brachial plexus injury: follow-up of two different fractionation schedules.

S. Powell, J. Cooke, C. Parsons, 1990, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

Pathogenic Mutations in ATM As Determinants of Local Control in Non-Small Cell Lung Cancers Treated with Radiation Therapy

J. Reis-Filho, N. Lee, N. Riaz, 2018, International Journal of Radiation Oncology*Biology*Physics.

A local ATR-dependent checkpoint pathway is activated by a 1 site-specific replication fork block in human cells. 2

S. Powell, C. Schildkraut, Settapong T. Kosiyatrakul, 2023 .

Taselisib (GDC-0032), a Potent β-Sparing Small Molecule Inhibitor of PI3K, Radiosensitizes Head and Neck Squamous Carcinomas Containing Activating PIK3CA Alterations

J. Baselga, G. Gupta, C. Chung, 2015, Clinical Cancer Research.

Utility of DNA Repair Protein Foci for the Detection of Putative BRCA1 Pathway Defects in Breast Cancer Biopsies

D. Sgroi, A. Taghian, S. Powell, 2009, Molecular Cancer Research.

Rad52 inactivation is synthetically lethal with BRCA2 deficiency

T. Pandita, S. Powell, S. Scott, 2010, Proceedings of the National Academy of Sciences.

Daily Fractionation of External Beam Accelerated Partial Breast Irradiation to 40 Gy Is Well Tolerated and Locally Effective.

J. Deasy, L. Braunstein, S. Powell, 2019, International journal of radiation oncology, biology, physics.