M. Holmes

发表

Proof of principle for epitope-focused vaccine design

David Baker, Eric Stevens, Man Chen, 2014, Nature.

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.

L. Stamatatos, David Baker, Y. Ban, 2010, Structure.

Structure of thermolysin refined at 1.6 A resolution.

B. Matthews, M. Holmes, B W Matthews, 1982, Journal of molecular biology.

Structure of ribose 5-phosphate isomerase from Plasmodium falciparum.

T. Earnest, J. Luft, F. Buckner, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

Crystallographic data for sturgeon holo-D-glyceraldehyde-3-phosphate dehydrogenase: a holo-D-glyceraldehyde-3-phosphate dehydrogenase with crystallographic 2-fold symmetry.

B. Matthews, S. Remington, M. Holmes, 1977, Journal of molecular biology.

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron

Shizuo Akira, Alan Aderem, S. Akira, 2004, Nature.

Structure of the conserved hypothetical protein MAL13P1.257 from Plasmodium falciparum.

Oleksandr Kalyuzhniy, Ethan A Merritt, Wim G J Hol, 2006, Acta crystallographica. Section F, Structural biology and crystallization communications.

High‐resolution structure prediction of a circular permutation loop

Po-Ssu Huang, W. Schief, B. Correia, 2011, Protein science : a publication of the Protein Society.

Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10

S. Elledge, L. Stamatatos, R. Strong, 2014, PLoS pathogens.

The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition.

R. Strong, M. Holmes, K. Raymond, 2002, Molecular cell.

on a Humanized Anti-Lysozyme Antibody Structural Effects of Framework Mutations

M. Holmes, J. Foote, T. Buss, 2001 .

CORRELATING DIFFERENTIAL EXPRESSION, PEPTIDE AFFINITIES, CRYSTAL STRUCTURES, AND THERMAL STABILITIES*

R. Strong, M. Holmes, D. Geraghty, 2003 .

Structures of deoxy and oxy hemerythrin at 2.0 A resolution.

L. Sieker, M. Holmes, S. Turley, 1991, Journal of molecular biology.

Structures of met and azidomet hemerythrin at 1.66 A resolution.

M. Holmes, R. Stenkamp, 1991, Journal of molecular biology.

Siderocalin/Lcn2/NGAL/24p3 Does Not Drive Apoptosis Through Gentisic Acid Mediated Iron Withdrawal in Hematopoietic Cell Lines

R. Strong, C. Correnti, A. Bandaranayake, 2012, PloS one.

Binding of hydroxamic acid inhibitors to crystalline thermolysin suggests a pentacoordinate zinc intermediate in catalysis.

B. Matthews, M. Holmes, B W Matthews, 1982, Biochemistry.

Structural Studies of Allelic Diversity of the MHC Class I Homolog MIC-B, a Stress-Inducible Ligand for the Activating Immunoreceptor NKG2D1

R. Strong, M. Holmes, E. Petersdorf, 2002, The Journal of Immunology.

Structural analysis of the inhibition of thermolysin by an active-site-directed irreversible inhibitor.

D E Tronrud, B. Matthews, M. Holmes, 1983, Biochemistry.

Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA

R. Strong, M. Holmes, T. Spies, 2011, Proceedings of the National Academy of Sciences.

Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestration.

Colin Ratledge, R. Strong, M. Holmes, 2005, Structure.

HLA-E Allelic Variants

R. Strong, M. Holmes, D. Geraghty, 2003, The Journal of Biological Chemistry.

“Superhumanized” Antibodies: Reduction of Immunogenic Potential by Complementarity-Determining Region Grafting with Human Germline Sequences: Application to an Anti-CD281

M. Holmes, J. Foote, C. Anasetti, 2002, The Journal of Immunology.

Structural Effects of Framework Mutations on a Humanized Anti-Lysozyme Antibody1

M. Holmes, J. Foote, Timothy N. Buss, 2001, The Journal of Immunology.

Conformational Correction Mechanisms Aiding Antigen Recognition by a Humanized Antibody

M. Holmes, J. Foote, Timothy N. Buss, 1998, The Journal of experimental medicine.

An oscillation data collection system for high‐resolution protein crystallography

B. Matthews, M. Schmid, D. Ohlendorf, 1981 .

Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity

L. Stamatatos, E. Reinherz, R. Strong, 2009, Journal of Virology.

Alternative metal-binding sites in rubrerythrin

L. Sieker, M. Holmes, B. Santarsiero, 1999, Nature Structural Biology.

Structure of a Trypanosoma brucei alpha/beta-hydrolase fold protein with unknown function.

E. Phizicky, J. Luft, F. Buckner, 2008, Acta crystallographica. Section F, Structural biology and crystallization communications.

Structural genomics of pathogenic protozoa: an overview.

David Baker, Thomas Earnest, Jürgen Bosch, 2008, Methods in molecular biology.

Immune interference in Mycobacterium tuberculosis intracellular iron acquisition through siderocalin recognition of carboxymycobactins.

R. Strong, M. Holmes, K. Raymond, 2011, ACS chemical biology.

Structural consequences of humanizing an antibody.

M. Holmes, J. Foote, M A Holmes, 1997, Journal of immunology.

Ribose 5-phosphate isomerase from Plasmodium falciparum

E. Merritt, M. Holmes, 2005 .

The 1.9 Å crystal structure of the “as isolated” rubrerythrin from Desulfovibrio vulgaris: some surprising results

L. Sieker, M. Holmes, S. Turley, 2000, JBIC Journal of Biological Inorganic Chemistry.

Crystal structures and proposed structural/functional classification of three protozoan proteins from the isochorismatase superfamily

K. Hodgson, T. Earnest, P. Myler, 2005, Protein Science.

Computational design of epitope-scaffolds allows induction of antibodies specific for a poorly immunogenic HIV vaccine epitope.

L. Stamatatos, David Baker, Y. Ban, 2010, Structure.