Yuxing Li

发表

Proof of principle for epitope-focused vaccine design

David Baker, Eric Stevens, Man Chen, 2014, Nature.

High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site

J. Mascola, R. Wyatt, Yuxing Li, 2012, Science Translational Medicine.

Immune selection of equine infectious anemia virus env variants during the long-term inapparent stage of disease.

S. Carpenter, Yuxing Li, J. Oaks, 2007, Virology.

Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

Mario Roederer, Tongqing Zhou, Gary J. Nabel, 2010, Science.

Diverse Antibody Genetic and Recognition Properties Revealed following HIV-1 Envelope Glycoprotein Immunization

J. Mascola, R. Wyatt, Yuxing Li, 2015, The Journal of Immunology.

HIV-1 Cross-Reactive Primary Virus Neutralizing Antibody Response Elicited by Immunization in Nonhuman Primates

J. Mascola, R. Wyatt, N. Doria-Rose, 2017, Journal of Virology.

Vaccine-elicited primate antibodies use a distinct approach to the HIV-1 primary receptor binding site informing vaccine redesign

Richard Wilson, Richard T. Wyatt, Robyn L. Stanfield, 2014, Proceedings of the National Academy of Sciences.

IgG3 regulates tissue-like memory B cells in HIV-infected individuals

Weiqi Wang, T. Chun, J. Justement, 2018, Nature Immunology.

Abnormal B cell memory subsets dominate HIV-specific responses in infected individuals.

N. Shah, T. Chun, A. Fauci, 2014, The Journal of clinical investigation.

Identification and Characterization of a Broadly Cross-Reactive HIV-1 Human Monoclonal Antibody That Binds to Both gp120 and gp41

D. Dimitrov, Yuxing Li, Richard Wilson, 2012, PloS one.

Identification and Characterization of a Broadly Cross-Reactive HIV-1 Human Monoclonal Antibody That Binds to Both gp 120 and gp

D. Dimitrov, Yuxing Li, Richard Wilson, 2012 .

HIV-1 Neutralizing Antibodies Display Dual Recognition of the Primary and Coreceptor Binding Sites and Preferential Binding to Fully Cleaved Envelope Glycoproteins

J. Mascola, R. Wyatt, M. Connors, 2012, Journal of Virology.

Sundling the HIV Primary Receptor Binding Site High-Resolution Definition of Vaccine-Elicited B Cell Responses Against

J. Mascola, R. Wyatt, Yuxing Li, 2012 .

Glycosylation, hypogammaglobulinemia, and resistance to viral infections.

M. Hegde, T. Chun, J. Justement, 2014, The New England journal of medicine.

De novo protein design enables precise induction of functional antibodies in vivo

B. Correia, P. Corthésy, J. Bates, 2020 .

Immunization-Elicited Broadly Protective Antibody Reveals Ebolavirus Fusion Loop as a Site of Vulnerability

J. Dye, A. Kuehne, K. Chandran, 2017, Cell.

Structural basis for broad neutralization of ebolaviruses by an antibody targeting the glycoprotein fusion loop

Cinque S. Soto, Nydia van Dyk, N. V. Dyk, 2018, Nature Communications.

HIV-1 Envgp140 trimers elicit neutralizing antibodies without efficient induction of conformational antibodies.

R. Wyatt, Yuxing Li, T. Ross, 2006, Vaccine.

147 Rational Design of Envelope Surface Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

J. Mascola, R. Wyatt, M. Connors, 2011 .

Early human B cell signatures of the primary antibody response to mRNA vaccination

W. Lau, T. Chun, A. Fauci, 2022, Proceedings of the National Academy of Sciences of the United States of America.

Analysis of Neutralization Speciﬁcities in Polyclonal Sera Derived from Human Immunodeﬁciency Virus Type 1-Infected Individuals (cid:1)

J. Mascola, R. Wyatt, S. Migueles, 2008 .

Influence of Novel CD4 binding-defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T Cell Responses in Non- human Primates Running title: Novel CD4 binding-defective HIV-1 Env immunogens

J. Mascola, R. Wyatt, Yuxing Li, 2009 .

One dose of COVID-19 nanoparticle vaccine REVC-128 protects against SARS-CoV-2 challenge at two weeks post-immunization

A. Ward, Yuxing Li, J. Torres, 2021, Emerging microbes & infections.

Broad HIV-1 neutralization mediated by CD4-binding site antibodies

Mark Connors, John R Mascola, J. Mascola, 2007, Nature Medicine.

A general approach for receptor and antibody-targeted detection of native proteins utilizing split-luciferase reassembly.

R. Wyatt, Yuxing Li, I. Ghosh, 2010, ACS chemical biology.

Maturational characteristics of HIV-specific antibodies in viremic individuals.

T. Chun, A. Fauci, E. Meffre, 2016, JCI insight.

Overexpression of T-bet in HIV infection is associated with accumulation of B cells outside germinal centers and poor affinity maturation

S. Pittaluga, T. Chun, J. Tsang, 2019, Science Translational Medicine.

Selective Expansion of HIV-1 Envelope Glycoprotein-Specific B Cell Subsets Recognizing Distinct Structural Elements Following Immunization1

J. Hoxie, R. Wyatt, Yuxing Li, 2009, The Journal of Immunology.

Following Immunization Recognizing Distinct Structural Elements Glycoprotein-Specific B Cell Subsets Selective Expansion of HIV-1 Envelope

J. Hoxie, R. Wyatt, Yuxing Li, 2009 .

Key gp120 Glycans Pose Roadblocks to the Rapid Development of VRC01-Class Antibodies in an HIV-1-Infected Chinese Donor.

J. Mascola, R. Wyatt, I. Wilson, 2016, Immunity.

Selection Pressure on HIV-1 Envelope by Broadly Neutralizing Antibodies to the Conserved CD4-Binding Site

Richard T. Wyatt, John R. Mascola, Mark Connors, 2012, Journal of Virology.

Prominent Neutralizing Antibody Response Targeting the Ebolavirus Glycoprotein Subunit Interface Elicited by Immunization

J. Dye, K. Chandran, E. Saphire, 2021, Journal of Virology.

HIV-1 Fitness Cost Associated with Escape from the VRC01 Class of CD4 Binding Site Neutralizing Antibodies

J. Mascola, Yuxing Li, S. O'dell, 2015, Journal of Virology.

Mechanism of Neutralization by the Broadly Neutralizing HIV-1 Monoclonal Antibody VRC01

Barney S. Graham, Richard T. Wyatt, John R. Mascola, 2011, Journal of Virology.

Analysis of Neutralization Specificities in Polyclonal Sera Derived from Human Immunodeficiency Virus Type 1-Infected Individuals

John R. Mascola, Mark K. Louder, Mark Connors, 2008, Journal of Virology.

Subpopulations of Equine Infectious Anemia Virus Rev Coexist In Vivo and Differ in Phenotype

J. Cornette, S. Carpenter, K. Dorman, 2003, Journal of Virology.

Rhesus Macaque B-Cell Responses to an HIV-1 Trimer Vaccine Revealed by Unbiased Longitudinal Repertoire Analysis

J. Mascola, R. Wyatt, K. Mckee, 2015, mBio.

Bone Marrow Plasma Cells Are a Primary Source of Serum HIV-1–Specific Antibodies in Chronically Infected Individuals

T. Chun, A. Fauci, S. Rosenzweig, 2015, The Journal of Immunology.

Analysis of the neutralizing antibody response elicited in rabbits by repeated inoculation with trimeric HIV-1 envelope glycoproteins.

Christoph Grundner, Joseph Sodroski, J. Sodroski, 2005, Virology.

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Richard T. Wyatt, Michael S. Seaman, John R. Mascola, 2009, Nature.

HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization

J. Mascola, R. Wyatt, K. Mckee, 2014, PLoS pathogens.

One dose of COVID-19 nanoparticle vaccine REVC-128 provides protection against SARS-CoV-2 challenge at two weeks post immunization

A. Ward, Yuxing Li, J. Torres, 2021, bioRxiv.

Characterization of Human Immunodeficiency Virus Type 1 Monomeric and Trimeric gp120 Glycoproteins Stabilized in the CD4-Bound State: Antigenicity, Biophysics, and Immunogenicity

Peter D. Kwong, John R. Mascola, Marie Pancera, 2007, Journal of Virology.

HIV-1 gp120–CD4-Induced Antibody Complex Elicits CD4 Binding Site–Specific Antibody Response in Mice

J. Mascola, A. Grishaev, N. Doria-Rose, 2020, The Journal of Immunology.

The HIV-1 Envelope Glycoprotein C3/V4 Region Defines a Prevalent Neutralization Epitope following Immunization

R. Wyatt, A. Ward, Yuxing Li, 2019, Cell reports.

An HIV-1 Env–Antibody Complex Focuses Antibody Responses to Conserved Neutralizing Epitopes

J. Mascola, R. Wyatt, Yuxing Li, 2016, The Journal of Immunology.

Biochemical and Immunogenic Characterization of Soluble Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers Expressed by Semliki Forest Virus

J. Mascola, R. Wyatt, Yuxing Li, 2005, Journal of Virology.

Structure-Based Stabilization of HIV-1 gp120 Enhances Humoral Immune Responses to the Induced Co-Receptor Binding Site

Tongqing Zhou, Gary J. Nabel, Peter D. Kwong, 2009, PLoS pathogens.

Reversible Reprogramming of Circulating Memory T Follicular Helper Cell Function during Chronic HIV Infection

S. Migueles, M. Connors, R. Koup, 2015, The Journal of Immunology.

Influence of Novel CD4 Binding-Defective HIV-1 Envelope Glycoprotein Immunogens on Neutralizing Antibody and T-Cell Responses in Nonhuman Primates

J. Mascola, R. Wyatt, Yuxing Li, 2009, Journal of Virology.

Characterization of Plasmablasts in the Blood of HIV-Infected Viremic Individuals: Evidence for Nonspecific Immune Activation

T. Chun, A. Fauci, Yuxing Li, 2013, Journal of Virology.

De novo protein design enables the precise induction of RSV-neutralizing antibodies

Luciano A. Abriata, John T. Bates, Bruno E. Correia, 2020, Science.

Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs

R. Wyatt, Yuxing Li, K. Tran, 2019, Front. Microbiol..

Maintenance of HIV-Specific Memory B-Cell Responses in Elite Controllers Despite Low Viral Burdens.

T. Chun, J. Justement, A. Fauci, 2016, The Journal of infectious diseases.

Focused dampening of antibody response to the immunodominant variable loops by engineered soluble gp140.

R. Doms, R. Wyatt, D. Burton, 2008, AIDS research and human retroviruses.

Rational design of a trispecific antibody targeting the HIV-1 Env with elevated anti-viral activity

J. Mascola, R. Bailer, M. Louder, 2018, Nature Communications.

Single-Cell and Deep Sequencing of IgG-Switched Macaque B Cells Reveal a Diverse Ig Repertoire following Immunization

J. Mascola, R. Wyatt, Zhenhai Zhang, 2014, The Journal of Immunology.

Tracking B cell responses to the SARS-CoV-2 mRNA-1273 vaccine

T. Chun, J. Tsang, S. Kleinstein, 2023, Cell reports.

HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation

J. Mascola, R. Wyatt, K. Mckee, 2016, Scientific Reports.

High-Resolution Longitudinal Study of HIV-1 Env Vaccine–Elicited B Cell Responses to the Virus Primary Receptor Binding Site Reveals Affinity Maturation and Clonal Persistence

J. Mascola, R. Wyatt, Yuxing Li, 2016, The Journal of Immunology.

Post-exposure immunotherapy for two ebolaviruses and Marburg virus in nonhuman primates

J. Dye, X. Qiu, G. Wong, 2019, Nature Communications.

Characterization of Antibody Responses Elicited by Human Immunodeficiency Virus Type 1 Primary Isolate Trimeric and Monomeric Envelope Glycoproteins in Selected Adjuvants

J. Mascola, R. Wyatt, Yuxing Li, 2006, Journal of Virology.

Pre-vaccination and early B cell signatures predict antibody response to SARS-CoV-2 mRNA vaccine

W. Lau, T. Chun, R. Davey, 2021, medRxiv.