B. Mordmüller

发表

A phase 3 trial of RTS,S/AS01 malaria vaccine in African infants.

Kwaku Poku Asante, M. Tanner, K. Marsh, 2012, The New England journal of medicine.

Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial.

Peter G. Kremsner, S. Agnandji, B. Lell, 2015 .

Sterile protection against human malaria by chemoattenuated PfSPZ vaccine

Sumana Chakravarty, Stephen L. Hoffman, Mihály Sulyok, 2017, Nature.

Atypical and classical memory B cells produce Plasmodium falciparum neutralizing antibodies

Beatrix Ueberheide, David Fenyo, Hedda Wardemann, 2013, The Journal of experimental medicine.

Clonal selection drives protective memory B cell responses in controlled human malaria infection

Thomas Höfer, Sumana Chakravarty, Hedda Wardemann, 2018, Science Immunology.

Plasmodia express two threonine-peptidase complexes during asexual development.

C. Gille, A. Nordheim, B. Mordmüller, 2006, Molecular and biochemical parasitology.

Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon

B. Mordmüller, P. Kremsner, A. Kreidenweiss, 2008, Malaria Journal.

Artesunate-clindamycin versus quinine-clindamycin in the treatment of Plasmodium falciparum malaria: a randomized controlled trial.

S. Agnandji, B. Lell, A. Adegnika, 2005, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Effect of Antihelminthic Treatment on Vaccine Immunogenicity to a Seasonal Influenza Vaccine in Primary School Children in Gabon: A Randomized Placebo-Controlled Trial

S. Agnandji, B. Lell, J. Fernandes, 2015, PLoS neglected tropical diseases.

Novel approaches in antimalarial drug discovery

B. Mordmüller, J. Held, A. Kreidenweiss, 2013, Expert opinion on drug discovery.

Nycteria and Polychromophilus parasite infections of bats in Central Gabon.

B. Mordmüller, K. Matuschewski, I. Eckerle, 2019, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Neutrophils and monocytes from subjects with the Mediterranean G6PD variant: effect of Plasmodium falciparum hemozoin on G6PD activity, oxidative burst and cytokine production.

B. Mordmüller, P. Kremsner, P. Arese, 1998, European Cytokine Network.

In vitro activity of new artemisinin derivatives against Plasmodium falciparum clinical isolates from Gabon.

B. Mordmüller, P. Kremsner, J. Held, 2011, International journal of antimicrobial agents.

In Vitro Activity of Mirincamycin (U24729A) against Plasmodium falciparum Isolates from Gabon

B. Mordmüller, P. Kremsner, J. Held, 2009, Antimicrobial Agents and Chemotherapy.

Molecular surveillance and genetic divergence of rotavirus A antigenic epitopes in Gabonese children with acute gastroenteritis

A. Adegnika, B. Mordmüller, P. Kremsner, 2021, EBioMedicine.

[Malaria therapy in the era of chloroquine resistance].

B. Mordmüller, P. Kremsner, W. Graninger, 1998, Wiener klinische Wochenschrift.

Increase in annexin V-positive B cells expressing LILRB1/ILT2/CD85j in malaria.

B. Mordmüller, P. Kremsner, R. Fendel, 2006, European cytokine network.

Use of Capillary Blood Samples Leads to Higher Parasitemia Estimates and Higher Diagnostic Sensitivity of Microscopic and Molecular Diagnostics of Malaria Than Venous Blood Samples

S. Agnandji, B. Lell, A. Adegnika, 2018, The Journal of infectious diseases.

Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon

S. Agnandji, A. Adegnika, B. Mordmüller, 2018, Antimicrobial Agents and Chemotherapy.

Broad-Spectrum Antimalarial Activity of Peptido Sulfonyl Fluorides, a New Class of Proteasome Inhibitors

Arwin J. Brouwer, B. Mordmüller, R. Liskamp, 2013, Antimicrobial Agents and Chemotherapy.

Title : Broad spectrum antimalarial activity of peptido sulfonyl fluorides , a new 1 class of proteasome inhibitors 2 Running title : Antimalarial activity of peptido sulfonyl fluorides 3 4

Arwin J. Brouwer, B. Mordmüller, A. J. Brouwer, 2013 .

DSM265 for Plasmodium falciparum chemoprophylaxis: a randomised, double blinded, phase 1 trial with controlled human malaria infection

S. Hoffman, B. Mordmüller, P. Kremsner, 2017, The Lancet. Infectious diseases.

Molecular epidemiology of respiratory syncytial virus in children in sub‐Saharan Africa

A. Sié, J. Fernandes, A. Adegnika, 2021, Tropical medicine & international health : TM & IH.

Clonal evolution and TCR specificity of the human TFH cell response to Plasmodium falciparum CSP

S. Hoffman, H. Wardemann, B. Mordmüller, 2022, Science Immunology.

Prospective Clinical and Molecular Evaluation of Potential Plasmodium ovale curtisi and wallikeri Relapses in a High-transmission Setting

S. Agnandji, A. Adegnika, B. Mordmüller, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Non-Invasive Antibody Assessment in Saliva to Determine SARS-CoV-2 Exposure in Young Children

B. Mordmüller, P. Kremsner, R. Fendel, 2021, Frontiers in Immunology.

Correlating efficacy and immunogenicity in malaria vaccine trials.

B. Mordmüller, P. Kremsner, M. McCall, 2018, Seminars in immunology.

Workshop report: Malaria vaccine development in Europe--preparing for the future.

A. Craig, B. Mordmüller, P. Kremsner, 2015, Vaccine.

A retinal model of cerebral malaria

T. Schubert, N. Tanimoto, S. Beck, 2019, Scientific Reports.

Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial

S. Hoffman, B. Lell, A. Adegnika, 2022, Malaria journal.

Effect of IL-15 on IgG versus IgE antibody-secreting cells in vitro.

B. Mordmüller, P. Kremsner, J. Forster, 2012, Journal of immunological methods.

Reduced CD3/TCR complex expression leads to immunosuppression during Plasmodium falciparum malaria

B. Mordmüller, P. Kremsner, M. Grobusch, 2009, Parasitology Research.

Parasites and pregnancy

B. Mordmüller, Meral Esen, M. Esen, 1996, Wiener klinische Wochenschrift.

Phase 1 Trials of rVSV Ebola Vaccine in Africa and Europe.

M. Altfeld, S. Yerly, M. Addo, 2016, The New England journal of medicine.

An efficient single‐cell based method for linking human T cell phenotype to T cell receptor sequence and specificity

S. Hoffman, C. Busse, H. Wardemann, 2021, European journal of immunology.

Notch ligands Delta‐like1, Delta‐like4 and Jagged1 differentially regulate activation of peripheral T helper cells

S. Rutz, A. Scheffold, B. Mordmüller, 2005, European journal of immunology.

Plasmodium falciparum 7G8 challenge provides conservative prediction of efficacy of PfNF54-based PfSPZ Vaccine in Africa

Joana C. Silva, S. Hoffman, B. Mordmüller, 2022, Nature Communications.

Life-span of in vitro differentiated Plasmodium falciparum gametocytes

B. Mordmüller, P. Kremsner, A. Lalremruata, 2017, Malaria Journal.

Heterologous protection against malaria by a simple chemoattenuated PfSPZ vaccine regimen in a randomized trial

S. Hoffman, B. Mordmüller, P. Kremsner, 2021, Nature Communications.

A PfSPZ vaccine immunization regimen equally protective against homologous and heterologous controlled human malaria infection

S. Hoffman, B. Mordmüller, P. Kremsner, 2022, NPJ vaccines.

Bats are rare reservoirs of Staphylococcus aureus complex in Gabon.

B. Mordmüller, K. Matuschewski, I. Eckerle, 2017, Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases.

Monitoring of efficacy, tolerability and safety of artemether–lumefantrine and artesunate–amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Lambaréné, Gabon: an open-label clinical trial

S. Agnandji, B. Lell, A. Adegnika, 2019, Malaria Journal.

Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon.

B. Cissé, B. Lell, B. Mordmüller, 2008, The Journal of infectious diseases.

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon

A. Adegnika, B. Mordmüller, P. Kremsner, 2012, Malaria Journal.

Genetic Diversity of Enteric Viruses in Children under Five Years Old in Gabon

A. Adegnika, B. Mordmüller, P. Kremsner, 2021, Viruses.

Induction of Plasmodium falciparum-Specific CD4+ T Cells and Memory B Cells in Gabonese Children Vaccinated with RTS,S/AS01E and RTS,S/AS02D

M. Demoitié, S. Agnandji, B. Lell, 2011, PloS one.

A call to caution when hydroxychloroquine is given to elderly patients with COVID-19

S. Kubicka, M. Addo, B. Mordmüller, 2021, International Journal of Infectious Diseases.

Extended follow-up of children in a phase2b trial of the GMZ2 malaria vaccine.

B. Mordmüller, P. Kremsner, S. Sirima, 2021, Vaccine.

Analysis of polymorphic sites in the promoter of the nitric oxide synthase 2 gene.

B. Mordmüller, J. Dengjel, G. Destro‐Bisol, 2005, Biochemical and biophysical research communications.

In vitro growth of Plasmodium falciparum in neonatal blood

B. Mordmüller, P. Kremsner, J. Mackanga, 2014, Malaria Journal.

Synthesis and study of cytotoxic activity of 1,2,4-trioxane- and egonol-derived hybrid molecules against Plasmodium falciparum and multidrug-resistant human leukemia cells.

T. Efferth, B. Mordmüller, S. Tsogoeva, 2014, European journal of medicinal chemistry.

Characterization of Plasmodium infections among inhabitants of rural areas in Gabon

B. Mordmüller, A. Lalremruata, M. Gmeiner, 2019, Scientific Reports.

Species and genotype diversity of Plasmodium in malaria patients from Gabon analysed by next generation sequencing

B. Mordmüller, P. Kremsner, M. Ramharter, 2017, Malaria Journal.

Natural infection of Plasmodium brasilianum in humans: Man and monkey share quartan malaria parasites in the Venezuelan Amazon

B. Mordmüller, D. J. Perkins, M. Magris, 2015, EBioMedicine.

Impact of Helminth Infections during Pregnancy on Vaccine Immunogenicity in Gabonese Infants

S. Agnandji, B. Lell, A. Adegnika, 2020, Vaccines.

Controlled Human Malaria Infection of Healthy Adults With Lifelong Malaria Exposure to Assess Safety, Immunogenicity, and Efficacy of the Asexual Blood Stage Malaria Vaccine Candidate GMZ2

B. Lell, A. Adegnika, B. Mordmüller, 2019 .

Controlled human malaria infection of healthy lifelong malaria-exposed adults to assess safety, immunogenicity and efficacy of the asexual blood stage malaria vaccine candidate GMZ2.

S. Hoffman, B. Lell, J. Fernandes, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

The GMZ2 malaria vaccine: from concept to efficacy in humans

B. Mordmüller, M. Theisen, Subhash Singh, 2017, Expert review of vaccines.

Controlled human malaria infection by intramuscular and direct venous inoculation of cryopreserved Plasmodium falciparum sporozoites in malaria-naïve volunteers: effect of injection volume and dose on infectivity rates

S. Hoffman, A. Garcia-Basteiro, B. Mordmüller, 2015, Malaria Journal.

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

S. Hoffman, B. Mordmüller, P. Kremsner, 2015, Malaria Journal.

Polymorphism in promoter region of inducible nitric oxide synthase gene and protection against malaria

B. Lell, B. Mordmüller, P. Kremsner, 1998, The Lancet.

Tumor necrosis factor in Plasmodium falciparum malaria: high plasma level is associated with fever, but high production capacity is associated with rapid fever clearance.

B. Mordmüller, P. Kremsner, B. Brinkman, 1997, European cytokine network.

Regional Variation of Extended-Spectrum Beta-Lactamase (ESBL)-Producing Enterobacterales, Fluoroquinolone-Resistant Salmonella enterica and Methicillin-Resistant Staphylococcus aureus Among Febrile Patients in Sub-Saharan Africa

A. Sié, E. Owusu-Dabo, J. Fernandes, 2020, Frontiers in Microbiology.

Increased levels of anti-PfCSP antibodies in post-pubertal females versus males immunized with PfSPZ Vaccine does not translate into increased protective efficacy

S. Hoffman, B. Mordmüller, P. Kremsner, 2022, Frontiers in Immunology.

Immunological profiles associated with distinct parasitemic states in volunteers undergoing malaria challenge in Gabon

S. Hoffman, B. Lell, A. Adegnika, 2022, Scientific Reports.

The frontline of controlled human malaria infections: A report from the controlled human infection models Workshop in Leiden University Medical Centre 5 May 2016.

B. Mordmüller, P. Kremsner, C. Ockenhouse, 2017, Vaccine.

First results of phase 3 trial of RTS,S/AS01 malaria vaccine in African children.

Pedro Alonso, Trudie Lang, Bernhards Ogutu, 2011, The New England journal of medicine.

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

S. Hoffman, A. Scheffold, B. Mordmüller, 2022, NPJ vaccines.

In vitro activity of ferroquine (SAR97193) is independent of chloroquine resistance in Plasmodium falciparum.

K. Dietz, B. Mordmüller, P. Kremsner, 2006, The American journal of tropical medicine and hygiene.

Recombinase Polymerase Amplification and Lateral Flow Assay for Ultrasensitive Detection of Low-Density Plasmodium falciparum Infection from Controlled Human Malaria Infection Studies and Naturally Acquired Infections

S. Hoffman, S. Agnandji, B. Lell, 2020, Journal of Clinical Microbiology.

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

B. Mordmüller, S. Issifou, M. Theisen, 2012, Malaria Journal.

In vitro activity of eravacycline, a novel synthetic halogenated tetracycline, against the malaria parasite Plasmodium falciparum.

S. Agnandji, A. Adegnika, B. Mordmüller, 2020, Journal of global antimicrobial resistance.

Ferroquine and artesunate in African adults and children with Plasmodium falciparum malaria: a phase 2, multicentre, randomised, double-blind, dose-ranging, non-inferiority study.

A. Sié, B. Lell, B. Mordmüller, 2015, The Lancet. Infectious diseases.

Effect of immune regulatory pathways after immunization with GMZ2 malaria vaccine candidate in healthy lifelong malaria-exposed adults.

S. Hoffman, S. Agnandji, B. Lell, 2020, Vaccine.

Ivermectin for causal malaria prophylaxis: a randomised controlled human infection trial

S. Hoffman, B. Mordmüller, P. Kremsner, 2019, Tropical medicine & international health : TM & IH.

Impact of Sickle Cell Trait and Naturally Acquired Immunity on Uncomplicated Malaria after Controlled Human Malaria Infection in Adults in Gabon

S. Hoffman, B. Lell, A. Adegnika, 2017, The American journal of tropical medicine and hygiene.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

S. Hoffman, H. Wardemann, J. Julien, 2018, Science.

First-in-human, Randomized, Double-blind Clinical Trial of Differentially Adjuvanted PAMVAC, A Vaccine Candidate to Prevent Pregnancy-associated Malaria

S. Reed, T. Theander, B. Mordmüller, 2019, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Delayed hemolysis after treatment with parenteral artesunate in African children with severe malaria--a double-center prospective study.

T. Rolling, A. Adegnika, B. Mordmüller, 2014, The Journal of infectious diseases.

8‐Aminoquinolines with an Aminoxyalkyl Side Chain Exert in vitro Dual‐Stage Antiplasmodial Activity

E. Winzeler, S. Meister, D. Plouffe, 2019, ChemMedChem.

Haematological and biochemical reference intervals for infants and children in Gabon

B. Lell, B. Mordmüller, P. Kremsner, 2011, Tropical medicine & international health : TM & IH.

IspC as target for antiinfective drug discovery: synthesis, enantiomeric separation, and structural biology of fosmidomycin thia isosters.

W. Eisenreich, A. Bacher, B. Mordmüller, 2013, Journal of medicinal chemistry.

Novel reverse thia-analogs of fosmidomycin: Synthesis and antiplasmodial activity.

A. Bacher, B. Mordmüller, T. Kurz, 2019, European journal of medicinal chemistry.

Binding modes of reverse fosmidomycin analogs toward the antimalarial target IspC.

A. Bacher, B. Mordmüller, T. Kurz, 2014, Journal of medicinal chemistry.

Loa loa-does it deserve to be neglected?

B. Mordmüller, W. Metzger, 2014, The Lancet. Infectious diseases.

Discovery of HDAC inhibitors with potent activity against multiple malaria parasite life cycle stages.

E. Winzeler, S. Meister, B. Mordmüller, 2014, European journal of medicinal chemistry.

Hemolysis Is Associated with Low Reticulocyte Production Index and Predicts Blood Transfusion in Severe Malarial Anemia

B. Mordmüller, P. Kremsner, W. Berdel, 2010, PloS one.

Boromycin has Rapid-Onset Antibiotic Activity Against Asexual and Sexual Blood Stages of Plasmodium falciparum

B. Mordmüller, P. Kremsner, J. Held, 2022, Frontiers in Cellular and Infection Microbiology.

High efficacy of short-term quinine-antibiotic combinations for treating adult malaria patients in an area in which malaria is hyperendemic

B. Mordmüller, P. Kremsner, W. Graninger, 1995, Antimicrobial agents and chemotherapy.

Emerging drugs for malaria

B. Mordmüller, P. Kremsner, S. Tschan, 2012, Expert opinion on emerging drugs.

Clinical and parasitological characteristics of puerperal malaria.

S. Agnandji, B. Lell, A. Adegnika, 2005, The Journal of infectious diseases.

Experimental infection of human volunteers.

B. Mordmüller, M. Yazdanbakhsh, M. Roestenberg, 2018, The Lancet. Infectious diseases.

A single-dose antihelminthic treatment does not influence immunogenicity of a meningococcal and a cholera vaccine in Gabonese school children.

S. Agnandji, B. Lell, J. Fernandes, 2016, Vaccine.

In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays

B. Mordmüller, P. Kremsner, M. Ramharter, 2009, Malaria Journal.

Ivermectin Impairs the Development of Sexual and Asexual Stages of Plasmodium falciparum In Vitro

B. Mordmüller, P. Kremsner, R. Fendel, 2019, Antimicrobial Agents and Chemotherapy.

Mosquito Passage Dramatically Changes Var Gene Expression in Controlled Human Plasmodium Falciparum Infections Author Summary

S. Hoffman, B. Mordmüller, P. Kremsner, 2022 .

Progress with Plasmodium falciparum sporozoite (PfSPZ)-based malaria vaccines

Pedro Alonso, Ogobara K. Doumbo, Robert W. Sauerwein, 2015, Vaccine.

Mitochondrial localization of the threonine peptidase PfHslV, a ClpQ ortholog in Plasmodium falciparum.

B. Mordmüller, Y. Stierhof, R. Fendel, 2010, International journal for parasitology.

Associations Between Helminth Infections, Plasmodium falciparum Parasite Carriage and Antibody Responses to Sexual and Asexual Stage Malarial Antigens.

T. Bousema, A. Adegnika, B. Mordmüller, 2016, The American journal of tropical medicine and hygiene.

Exploratory analysis of the effect of helminth infection on the immunogenicity and efficacy of the asexual blood-stage malaria vaccine candidate GMZ2

S. Hoffman, S. Agnandji, B. Lell, 2021, PLoS neglected tropical diseases.

Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

B. Lell, A. Adegnika, B. Mordmüller, 2019, Parasites & Vectors.

Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

B. Lell, A. Adegnika, B. Mordmüller, 2019, Parasites & Vectors.

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

A. Adegnika, B. Mordmüller, S. Issifou, 2017, Malaria Journal.

Assessment of malaria transmission intensity and insecticide resistance mechanisms in three rural areas of the Moyen Ogooué Province of Gabon

A. Adegnika, B. Mordmüller, P. Kremsner, 2022, Parasites & vectors.

Alterations of blood coagulation in controlled human malaria infection

S. Hoffman, B. Mordmüller, P. Kremsner, 2016, Malaria Journal.

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children.

M. Christiansen, B. Mordmüller, S. Issifou, 2016, Vaccine.

The malaria vaccine candidate GMZ2 elicits functional antibodies in individuals from malaria endemic and non-endemic areas.

M. Christiansen, B. Mordmüller, S. Issifou, 2013, The Journal of infectious diseases.

Reduced antibody responses against Plasmodium falciparum vaccine candidate antigens in the presence of Trichuris trichiura.

S. Agnandji, A. Adegnika, B. Mordmüller, 2012, Vaccine.

Demography, maternal health and the epidemiology of malaria and other major infectious diseases in the rural department Tsamba-Magotsi, Ngounie Province, in central African Gabon

S. Agnandji, B. Lell, B. Mordmüller, 2017, BMC Public Health.

Burden of disease in Gabon caused by loiasis: a cross-sectional survey.

S. Agnandji, A. Adegnika, B. Mordmüller, 2020, The Lancet. Infectious diseases.

Behavioural and clinical predictors for Loiasis

B. Mordmüller, J. Mischlinger, M. Ramharter, 2018, Journal of global health.

DNA recovery from archived RDTs for genetic characterization of Plasmodium falciparum in a routine setting in Lambaréné, Gabon

S. Agnandji, B. Lell, A. Adegnika, 2019, Malaria Journal.

Characterization of Plasmodium infections among inhabitants of rural areas in Gabon

B. Mordmüller, A. Lalremruata, M. Gmeiner, 2019, Scientific Reports.

Efficacy and Safety of Fosmidomycin–Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon

B. Lell, A. Adegnika, B. Mordmüller, 2017, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

History and perspectives of medical research at the Albert Schweitzer Hospital in Lambaréné, Gabon

S. Agnandji, B. Lell, A. Adegnika, 2007, Wiener klinische Wochenschrift.

A rapid malaria appraisal in the Venezuelan Amazon

B. Mordmüller, M. Magris, S. Vivas-Martínez, 2009, Malaria Journal.

Genome, proteome, and immunome data explain why 6 month controlled human malaria infection with sporozoites of the Pf7G8 clone of Plasmodium falciparum is a rigorous predictor of the efficacy of the PfNF54-based PfSPZ Vaccine in Africa

Joana C. Silva, S. Hoffman, B. Mordmüller, 2021, medRxiv.

Molecular epidemiology of Mansonella species in Gabon.

B. Mordmüller, M. Ramharter, M. Gmeiner, 2020, The Journal of infectious diseases.

Development and evaluation of a multiplex screening assay for Plasmodium falciparum exposure.

M. Christiansen, B. Mordmüller, D. Cavanagh, 2012, Journal of immunological methods.

Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial

K. Bojang, T. Taylor, B. Mordmüller, 2016, PLoS medicine.

High-throughput tri-colour flow cytometry technique to assess Plasmodium falciparum parasitaemia in bioassays

M. Christiansen, B. Mordmüller, S. Sirima, 2014, Malaria Journal.

Schistosoma co-infection protects against brain pathology but does not prevent severe disease and death in a murine model of cerebral malaria.

K. Dietz, B. Mordmüller, R. Fendel, 2011, International journal for parasitology.

Transcriptional correlates of malaria in RTS,S/AS01-vaccinated African children: a matched case–control study

Lindsay N. Carpp, R. Gottardo, Greg Finak, 2022, eLife.

Randomized, Controlled, Assessor-Blind Clinical Trial To Assess the Efficacy of Single- versus Repeated-Dose Albendazole To Treat Ascaris lumbricoides, Trichuris trichiura, and Hookworm Infection

S. Agnandji, B. Lell, A. Adegnika, 2014, Antimicrobial Agents and Chemotherapy.

Expansion of Functional Myeloid-Derived Suppressor Cells in Controlled Human Malaria Infection

S. Hoffman, B. Mordmüller, P. Kremsner, 2021, Frontiers in Immunology.

Life-span of in vitro differentiated Plasmodium falciparum gametocytes

B. Mordmüller, P. Kremsner, A. Lalremruata, 2017, Malaria Journal.

Limit of blank and limit of detection of Plasmodium falciparum thick blood smear microscopy in a routine setting in Central Africa

B. Lell, B. Mordmüller, T. Engleitner, 2014, Malaria Journal.

Validity and reliability of methods to microscopically detect and quantify malaria parasitaemia

B. Lell, A. Adegnika, B. Mordmüller, 2018, Tropical medicine & international health : TM & IH.

In vitro growth of Plasmodium falciparum in neonatal blood

B. Mordmüller, P. Kremsner, J. Mackanga, 2014, Malaria Journal.

Prospective evaluation of artemether-lumefantrine for the treatment of non-falciparum and mixed-species malaria in Gabon

A. Adegnika, B. Mordmüller, P. Kremsner, 2012, Malaria Journal.

Rare PfCSP C-terminal antibodies induced by live sporozoite vaccination are ineffective against malaria infection

S. Hoffman, H. Wardemann, J. Julien, 2018, The Journal of experimental medicine.

Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial

M. Kieny, S. Agnandji, B. Lell, 2017, PLoS medicine.

Natural Parasite Exposure Induces Protective Human Anti‐Malarial Antibodies

S. Kappe, H. Wardemann, E. Marois, 2017, Immunity.

The effect of immunization schedule with the malaria vaccine candidate RTS,S/AS01E on protective efficacy and anti-circumsporozoite protein antibody avidity in African infants

Kwaku Poku Asante, M. Tanner, S. Agnandji, 2015, Malaria Journal.

Safety and immunogenicity of GMZ2 - a MSP3-GLURP fusion protein malaria vaccine candidate.

B. Mordmüller, P. Kremsner, J. Knobloch, 2009, Vaccine.

First-in-human use of a modular capsid virus-like vaccine platform: an open-label, non-randomised, phase 1 clinical trial of the SARS-CoV-2 vaccine ABNCoV2

H. Wertheim, J. Bukh, S. Justesen, 2023, The Lancet Microbe.

Clinical development of a VAR2CSA-based placental malaria vaccine PAMVAC: Quantifying vaccine antigen-specific memory B & T cell activity in Beninese primigravidae.

B. Mordmüller, S. Issifou, K. Moutairou, 2017, Vaccine.

Humoral immune response to Plasmodium falciparum vaccine candidate GMZ2 and its components in populations naturally exposed to seasonal malaria in Ethiopia

B. Mordmüller, M. Theisen, B. Petros, 2013, Malaria Journal.

A flow cytometry-based workflow for detection and quantification of anti-plasmodial antibodies in vaccinated and naturally exposed individuals

B. Mordmüller, S. Issifou, M. Theisen, 2012, Malaria Journal.

Naturally acquired immune responses to malaria vaccine candidate antigens MSP3 and GLURP in Guahibo and Piaroa indigenous communities of the Venezuelan Amazon

B. Mordmüller, L. Avilan, M. Theisen, 2012, Malaria Journal.

A Randomized Controlled Phase Ib Trial of the Malaria Vaccine Candidate GMZ2 in African Children

R. Noor, B. Mordmüller, S. Issifou, 2011, PloS one.

Safety and immunogenicity of the malaria vaccine candidate GMZ2 in malaria-exposed, adult individuals from Lambaréné, Gabon.

R. Noor, W. Kilama, B. Mordmüller, 2010, Vaccine.

New medicines for malaria

B. Mordmüller, 2010, Wiener klinische Wochenschrift.

Clonal evolution and specificity of the human T follicular helper cell response to Plasmodium falciparum circumsporozoite protein

S. Hoffman, H. Wardemann, B. Mordmüller, 2021, bioRxiv.

Human Plasmodium vivax diversity, population structure and evolutionary origin

R. Haque, F. Nosten, L. Musset, 2020, PLoS neglected tropical diseases.

Controlled human malaria infection with Plasmodium falciparum demonstrates impact of naturally acquired immunity on virulence gene expression

S. Hoffman, B. Lell, B. Mordmüller, 2019, PLoS pathogens.

Severe malaria in children leads to a significant impairment of transitory otoacoustic emissions - a prospective multicenter cohort study

A. Adegnika, B. Mordmüller, S. Issifou, 2015, BMC Medicine.

Plasmodium vivax malaria in Duffy-negative individuals from Ethiopia.

B. Mordmüller, P. Kremsner, J. Kun, 2013, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Growth Rate of Plasmodium falciparum: Analysis of Parasite Growth Data from Malaria Volunteer Infection Studies

J. Kublin, J. McCarthy, B. Mordmüller, 2019, The Journal of infectious diseases.

Lymphotoxin and lipopolysaccharide induce NF‐κB‐p52 generation by a co‐translational mechanism

B. Mordmüller, C. Scheidereit, D. Krappmann, 2003, EMBO reports.

Characterisation of a tryptophan-rich Plasmodium falciparum antigen associated with merozoites.

B. Mordmüller, P. Kremsner, A. Uhlemann, 2004, Molecular and biochemical parasitology.

Transcriptome profiling reveals functional variation in Plasmodium falciparum parasites from controlled human malaria infection studies

S. Hoffman, Zbynek Bozdech, B. Mordmüller, 2019, EBioMedicine.

The Influence of Sub-Unit Composition and Expression System on the Functional Antibody Response in the Development of a VAR2CSA Based Plasmodium falciparum Placental Malaria Vaccine

T. Theander, B. Mordmüller, P. Kremsner, 2015, PloS one.

In Vitro Activity of Fluorescent Dyes against Asexual Blood Stages of Plasmodium falciparum

B. Mordmüller, J. Held, Fanny Joanny, 2012, Antimicrobial Agents and Chemotherapy.

Neutrophil alterations in pregnancy‐associated malaria and induction of neutrophil chemotaxis by Plasmodium falciparum

A. Adegnika, B. Mordmüller, V. Brinkmann, 2017, Parasite immunology.

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding domain elicit strong virus neutralization activity

H. Ullum, S. Buus, M. Skrzypczak, 2021, Nature Communications.

Antimalarial Activity of the Myxobacterial Macrolide Chlorotonil A

B. Mordmüller, R. Müller, K. Gerth, 2014, Antimicrobial Agents and Chemotherapy.

Prodrugs of reverse fosmidomycin analogues.

A. Bacher, B. Mordmüller, T. Kurz, 2015, Journal of medicinal chemistry.

A simplified intravenous artesunate regimen for severe malaria.

J. Simpson, T. Taylor, B. Mordmüller, 2012, The Journal of infectious diseases.

Threonine peptidases as drug targets against malaria

B. Mordmüller, J. Kun, S. Tschan, 2011, Expert opinion on therapeutic targets.

Experimental infections in humans—historical and ethical reflections

B. Mordmüller, P. Kremsner, Hans-Jörg Ehni, 2019, Tropical medicine & international health : TM & IH.

3-Hydroxy-propanamidines, a New Class of Orally Active Antimalarials Targeting Plasmodium falciparum.

D. Fidock, B. Mordmüller, John Okombo, 2021, Journal of medicinal chemistry.

Human collectin-11 (COLEC11) and its synergic genetic interaction with MASP2 are associated with the pathophysiology of Chagas Disease

A. Boldt, B. Mordmüller, Meral Esen, 2019, PLoS neglected tropical diseases.

New method to quantify erythrophagocytosis by autologous monocytes

B. Mordmüller, P. Kremsner, W. Berdel, 2007, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

Design and Synthesis of Novel Anti‐Plasmodial Histone Deacetylase Inhibitors Containing an Alkoxyamide Connecting Unit

Jessica A. Engel, B. Mordmüller, F. Hansen, 2017, Archiv der Pharmazie.

Malarial parasites vs. antimalarials: never-ending rumble in the jungle.

B. Mordmüller, P. Kremsner, 2006, Current molecular medicine.

3-Hydroxy-N'-arylidenepropanehydrazonamides with Halo-Substituted Phenanthrene Scaffolds Cure P. berghei Infected Mice When Administered Perorally.

E. Winzeler, S. Meister, B. Mordmüller, 2017, Journal of medicinal chemistry.

Blood schizontocidal and gametocytocidal activity of 3-hydroxy-N'-arylidenepropanehydrazonamides: a new class of antiplasmodial compounds.

B. Mordmüller, K. Kuna, W. Frank, 2014, Journal of medicinal chemistry.

Fosmidomycin as an antimalarial drug: a meta-analysis of clinical trials.

Q. Bassat, S. Agnandji, B. Lell, 2015, Future microbiology.

Assessment of LED fluorescence microscopy for the diagnosis of Plasmodium falciparum infections in Gabon

B. Lell, A. Adegnika, B. Mordmüller, 2011, Malaria Journal.

2A and the Auxin-Based Degron System Facilitate Control of Protein Levels in Plasmodium falciparum

B. Mordmüller, A. Kreidenweiss, Annika V. Hopkins, 2013, PloS one.

A retinal model of cerebral malaria

T. Schubert, N. Tanimoto, S. Beck, 2019, Scientific Reports.

Selection of a trioxaquine as an antimalarial drug candidate

B. Mordmüller, P. Kremsner, J. Maffrand, 2008, Proceedings of the National Academy of Sciences.

Effect of Fluorescent Dyes on In Vitro-Differentiated, Late-Stage Plasmodium falciparum Gametocytes

B. Mordmüller, J. Held, T. Gebru, 2014, Antimicrobial Agents and Chemotherapy.

Real-time measurement of Plasmodium falciparum-infected erythrocyte cytoadhesion with a quartz crystal microbalance

H. Northoff, B. Mordmüller, J. Held, 2016, Malaria Journal.

Systems analysis and controlled malaria infection in Europeans and Africans elucidate naturally acquired immunity

E. Eisemann, J. Goeman, S. Hoffman, 2021, Nature Immunology.

Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry

B. Maček, A. Nordheim, B. Mordmüller, 2012, Amino Acids.

Novel approaches to whole sporozoite vaccination against malaria✩

S. Kappe, B. Mordmüller, B. Sack, 2015, Vaccine.

Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon

S. Agnandji, B. Lell, A. Adegnika, 2021, Wiener klinische Wochenschrift.

Sulfadoxine/pyrimethamine or chloroquine/clindamycin treatment of Gabonese school children infected with chloroquine resistant malaria.

B. Mordmüller, P. Kremsner, W. Graninger, 1995, The Journal of antimicrobial chemotherapy.

Malaria pigment in leucocytes.

B. Mordmüller, P. Kremsner, W. Metzger, 1995, Transactions of the Royal Society of Tropical Medicine and Hygiene.

Efficacy, T cell activation and antibody responses in accelerated Plasmodium falciparum sporozoite chemoprophylaxis vaccine regimens

S. Hoffman, A. Scheffold, B. Mordmüller, 2022, npj Vaccines.

Antimalarial Activity of a Synthetic Endoperoxide (RBx-11160/OZ277) against Plasmodium falciparum Isolates from Gabon

B. Mordmüller, P. Kremsner, S. Krishna, 2006, Antimicrobial Agents and Chemotherapy.

Direct venous inoculation of Plasmodium falciparum sporozoites for controlled human malaria infection: a dose-finding trial in two centres

S. Hoffman, B. Mordmüller, P. Kremsner, 2015, Malaria Journal.

Correction to: Schistosoma haematobium infection morbidity, praziquantel effectiveness and reinfection rate among children and young adults in Gabon

B. Lell, A. Adegnika, B. Mordmüller, 2021, Parasites & vectors.

Cellular and antibody response in GMZ2-vaccinated Gabonese volunteers in a controlled human malaria infection trial

S. Hoffman, B. Lell, A. Adegnika, 2022, Malaria journal.

Recognition of Plasmodium falciparum mature gametocyte-infected erythrocytes by antibodies of semi-immune adults and malaria-exposed children from Gabon

A. Adegnika, B. Mordmüller, S. Issifou, 2017, Malaria Journal.

Antihomotypic affinity maturation improves human B cell responses against a repetitive epitope

S. Hoffman, H. Wardemann, J. Julien, 2018, Science.

The exception that proves the rule: Virulence gene expression at the onset of Plasmodium falciparum blood stage infections

Joana C. Silva, S. Hoffman, T. Gilberger, 2022, medRxiv.

Lessons from a modern review of the smallpox eradication files

B. Mordmüller, W. Metzger, C. Köhler, 2015, Journal of the Royal Society of Medicine.

Molecular and functional properties of human Plasmodium falciparum CSP C‐terminus antibodies

S. Hoffman, H. Wardemann, J. Julien, 2023, bioRxiv.

In vitro activity of tigecycline in Plasmodium falciparum culture-adapted strains and clinical isolates from Gabon.

B. Mordmüller, S. Issifou, P. Kremsner, 2010, International journal of antimicrobial agents.

Unbiased metagenomic next-generation sequencing of blood from hospitalized febrile children in Gabon

M. Docquier, J. Fernandes, B. Mordmüller, 2020, Emerging microbes & infections.

Cytokine and chemokine profile of the innate and adaptive immune response of schistosoma haematobium and plasmodium falciparum single and co-infected school-aged children from an endemic area of Lambaréné, Gabon

A. Adegnika, B. Mordmüller, P. Kremsner, 2015, Malaria Journal.

Molecular epidemiology of Respiratory Syncytial Virus in children in sub-Saharan Africa.

A. Sié, J. Fernandes, B. Mordmüller, 2021, Tropical medicine & international health : TM & IH.

Causes of fever in Gabonese children: a cross-sectional hospital-based study

S. Agnandji, B. Lell, J. Fernandes, 2020, Scientific Reports.

HHV-6 infections in hospitalized young children of Gabon

S. Agnandji, B. Lell, J. Fernandes, 2023, Infection.

Antischistosome IgG4 and IgE responses are affected differentially by chemotherapy in children versus adults.

B. Mordmüller, P. Kremsner, A. Deelder, 1996, The Journal of infectious diseases.

Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon

S. Agnandji, A. Adegnika, B. Mordmüller, 2018, Antimicrobial Agents and Chemotherapy.

Mapping of safe and early chemo-attenuated live Plasmodium falciparum immunization identifies immune signature of vaccine efficacy

S. Hoffman, B. Mordmüller, P. Kremsner, 2020, bioRxiv.

Sporozoite immunization: innovative translational science to support the fight against malaria

Joana C. Silva, S. Hoffman, A. Dicko, 2023, Expert review of vaccines.

Causes of fever in Gabonese children: a cross-sectional hospital-based study

S. Agnandji, B. Lell, J. Fernandes, 2020, Scientific Reports.

Sporozoite Route of Infection Influences In Vitro var Gene Transcription of Plasmodium falciparum Parasites From Controlled Human Infections.

S. Hoffman, B. Mordmüller, P. Kremsner, 2016, The Journal of infectious diseases.

Hyperparasitemia and blood exchange transfusion for treatment of children with falciparum malaria.

B. Mordmüller, P. Kremsner, B. Mordmüller, 1998, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Haematological and biochemical reference intervals for infants and children in Gabon

B. Lell, B. Mordmüller, P. Kremsner, 2011, Tropical medicine & international health : TM & IH.

On-line Detection of Plasmodium falciparum Sequestration By Thickness Shear Mode Sensors

H. Northoff, B. Mordmüller, F. Gehring, 2011 .

Alterations of blood coagulation in controlled human malaria infection

Michael Ramharter, S. Hoffman, B. Mordmüller, 2016, Malaria Journal.

Safety and efficacy of the choline analogue SAR97276 for malaria treatment: results of two phase 2, open-label, multicenter trials in African patients

S. Abdulla, A. Sié, B. Mordmüller, 2017, Malaria Journal.

Quinine plus clindamycin improves chemotherapy of severe malaria in children

B. Mordmüller, P. Kremsner, J. Prada, 1995, Antimicrobial agents and chemotherapy.

Analysis of the Plasmodium falciparum proteasome using Blue Native PAGE and label-free quantitative mass spectrometry

Alfred Nordheim, Karsten Krug, Boris Macek, 2012, Amino Acids.

Broad-Spectrum Antimalarial Activity of Peptido Sulfonyl Fluorides, a New Class of Proteasome Inhibitors

Arwin J. Brouwer, B. Mordmüller, R. Liskamp, 2013, Antimicrobial Agents and Chemotherapy.

Mosquito Passage Dramatically Changes var Gene Expression in Controlled Human Plasmodium falciparum Infections

B. Mordmüller, E. Tannich, Meral Esen, 2016, PLoS pathogens.

A phase 2b randomized, controlled trial of the efficacy of the GMZ2 malaria vaccine in African children.

M. Christiansen, B. Mordmüller, S. Issifou, 2016, Vaccine.